EVOLUTIONARY ANALYSIS OF
MAMMALIAN GENOMES AND
ASSOCIATIONS TO HUMAN DISEASE
JESSICA JANAKI VAMATHEVAN
Department of Biology
University College London
2008
Submitted to University College London
for the degree of Doctor of Philosophy
AUTHORSHIP DECLARATION
I, Jessica Janaki Vamathevan, confirm that the work presented in this thesis is my own. Where information has been derived from other sources, I confirm that this has been indicated in the thesis.
2 ABSTRACT
Statistical models of DNA sequence evolution for analysing protein