Toxicological Profile for Bromomethane

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BROMOMETHANE 72 CHAPTER 4. CHEMICAL AND PHYSICAL INFORMATION 4.1 CHEMICAL IDENTITY Table 4-1 lists common synonyms, trade names, and other pertinent identification information for bromomethane. Table 4-1. Chemical Identity of Bromomethane Characteristic Information Reference Chemical name Bromomethane Windholz 1983 Synonym(s) and registered Methyl bromide; monobromomethane; EPA 1986b; IRIS 2002 trade name(s) methyl fume; Embafume; Terabol Chemical formula CH3Br Windholz 1983 Chemical structure H Windholz 1983 H C Br H CAS Registry Number 74-83-9 Sax and Lewis 1987 CAS = Chemical Abstracts Service 4.2 PHYSICAL AND CHEMICAL PROPERTIES Table 4-2 lists important physical and chemical properties of bromomethane. Table 4-2. Physical and Chemical Properties of Bromomethane Property Information Reference Molecular weight 94.94 HSDB 2014 Color Colorless HSDB 2014 Physical state Gas HSDB 2014 Melting point -93.68°C HSDB 2014 Boiling point 3.5°C HSDB 2014 Density at 20°Ca 3.97 at 20°C (gas); 1.73 at 0°C (liquid) HSDB 2014 Odor Usually odorless; sweetish chloroform-like odor at HSDB 2014 high concentrations Odor threshold: Water No data Air 80 mg/m3 (20 ppm) Ruth 1986 BROMOMETHANE 73 4. CHEMICAL AND PHYSICAL INFORMATION Table 4-2. Physical and Chemical Properties of Bromomethane Solubility: Water at 20°C 15.2 g/L at 25°C HSDB 2014 18.5 g/L at 20°C 13.4 g/L at 25°C Organic solvents Readily soluble in lower alcohols, ethers, esters, HSDB 2014 ketones, halogenated hydrocarbons, aromatic hydrocarbons, and carbon disulfide; freely soluble in benzene, carbon tetrachloride, and carbon disulfide; miscible in ethanol and chloroform Partition coefficients: Log Kow 1.19 HSDB 2014 Log Koc 0.95–1.3 Yates et al. 2003 Vapor pressure at 20°C 1,420 mmHg HSDB 2014 Henry's law constant at 25°C 0.00734 atm m3/mole HSDB 2014 Autoignition temperature Nonflammable EPA 1986b Flashpoint Nonflammable EPA 1986b Flammability limits Nonflammable EPA 1986b Conversion factorsb 1 ppm=3.88 mg/m3 1 mg/m3=0.26 ppm Explosive limits Nonflammable EPA 1986b aDensity of vapor relative to air. bBased on the following formulas: ppm = (mg/m3) (24.45)/ (molecular weight), and mg/m3 = (ppm) (molecular weight)/ 24.45. .

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Bromomethane CAS #: 74-83-9 Revised By: RRD Toxicology Unit Revision Date: August 14, 2015
CHEMICAL UPDATE WORKSHEET Chemical Name: Bromomethane CAS #: 74-83-9 Revised By: RRD Toxicology Unit Revision Date: August 14, 2015 (A) Chemical-Physical Properties Part 201 Value Updated Value Reference Source Comments Molecular Weight (g/mol) 94.94 94.94 EPI EXP Physical State at ambient temp Liquid Gas MDEQ Melting Point (˚C) 179 -93.70 EPI EXP Boiling Point (˚C) 3.5 3.50 EPI EXP Solubility (ug/L) 1.45E+7 1.52E+07 EPI EXP Vapor Pressure (mmHg at 25˚C) 1672 1.62E+03 EPI EXP HLC (atm-m³/mol at 25˚C) 1.42E-2 7.34E-03 EPI EXP Log Kow (log P; octanol-water) 1.18 1.19 EPI EXP Koc (organic carbon; L/Kg) 14.5 13.22 EPI EST Ionizing Koc (L/kg) NR NA NA Diffusivity in Air (Di; cm2/s) 0.08 1.00E-01 W9 EST Diffusivity in Water (Dw; cm2/s) 8.0E-6 1.3468E-05 W9 EST CHEMICAL UPDATE WORKSHEET Bromomethane (74-83-9) Part 201 Value Updated Value Reference Source Comments Soil Water Partition Coefficient NR NR NA NA (Kd; inorganics) Flash Point (˚C) NA 194 PC EXP Lower Explosivity Level (LEL; 0.1 0.1 CRC EXP unit less) Critical Temperature (K) 467.00 EPA2004 EXP Enthalpy of Vaporization 5.71E+03 EPA2004 EXP (cal/mol) Density (g/mL, g/cm3) 1.6755 CRC EXP EMSOFT Flux Residential 2 m 2.69E-05 2.80E-05 EMSOFT EST (mg/day/cm2) EMSOFT Flux Residential 5 m 6.53E-05 6.86E-05 EMSOFT EST (mg/day/cm2) EMSOFT Flux Nonresidential 2 m 3.83E-05 4.47E-05 EMSOFT EST (mg/day/cm2) EMSOFT Flux Nonresidential 5 m 9.24E-05 1.09E-04 EMSOFT EST (mg/day/cm2) 2 CHEMICAL UPDATE WORKSHEET Bromomethane (74-83-9) (B) Toxicity Values/Benchmarks Source/Reference/ Comments/Notes Part 201 Value Updated Value Date /Issues Reference Dose 1.4E-3 2.0E-2 OPP, 2013 (RfD) (mg/kg/day) Rat subchronic Tier 1 Source: Complete gavage study EPA-OPP: (Danse et al., Basis: OPP is the more current than IRIS, PPRTV and ATSDR.
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