Radiodiagnosis Training Program Curriculum Version 2
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Educational Paper Ciliopathies
Eur J Pediatr (2012) 171:1285–1300 DOI 10.1007/s00431-011-1553-z REVIEW Educational paper Ciliopathies Carsten Bergmann Received: 11 June 2011 /Accepted: 3 August 2011 /Published online: 7 September 2011 # The Author(s) 2011. This article is published with open access at Springerlink.com Abstract Cilia are antenna-like organelles found on the (NPHP) . Ivemark syndrome . Meckel syndrome (MKS) . surface of most cells. They transduce molecular signals Joubert syndrome (JBTS) . Bardet–Biedl syndrome (BBS) . and facilitate interactions between cells and their Alstrom syndrome . Short-rib polydactyly syndromes . environment. Ciliary dysfunction has been shown to Jeune syndrome (ATD) . Ellis-van Crefeld syndrome (EVC) . underlie a broad range of overlapping, clinically and Sensenbrenner syndrome . Primary ciliary dyskinesia genetically heterogeneous phenotypes, collectively (Kartagener syndrome) . von Hippel-Lindau (VHL) . termed ciliopathies. Literally, all organs can be affected. Tuberous sclerosis (TSC) . Oligogenic inheritance . Modifier. Frequent cilia-related manifestations are (poly)cystic Mutational load kidney disease, retinal degeneration, situs inversus, cardiac defects, polydactyly, other skeletal abnormalities, and defects of the central and peripheral nervous Introduction system, occurring either isolated or as part of syn- dromes. Characterization of ciliopathies and the decisive Defective cellular organelles such as mitochondria, perox- role of primary cilia in signal transduction and cell isomes, and lysosomes are well-known -
Unresolved, Atraumatic Breast Hematoma: Post-Irradiation Or Secondary Breast Angiosarcoma
Breast Disease 33 (2011/2012) 139142 139 DOI 10.3233/BD-2012-0331 IOS Press Case Report Unresolved, atraumatic breast hematoma: Post-irradiation or secondary breast angiosarcoma Glenn Hanna, Samuel J. Lin, Michael D. Wertheimer and Ranjna Sharma Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA Department of Plastic and Reconstructive Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA Abstract. Post-irradiation or secondary angiosarcoma of the breast was rst described in the 1980s in patients treated with breast conserving therapy for cancer. The primary management of radiation-induced breast angiosarcoma has focused on surgical resection with an emphasis on achieving negative tumor margins. While surgery remains a key component of treatment, novel therapeutic approaches have surfaced. Despite such advances in treatment, prognosis remains poor. Keywords: Breast cancer, breast conservation therapy, secondary angiosarcoma 1. Clinical scenario amination showed the left breast to be larger than the right, with a 10 15cm areaofa clinicalhematomalo- A 64-year-old post-menopausal Caucasian female cated in the superior and inferior outer quadrants. The presented to our institution with a seven month history overlying skin was hemorrhagic, necrotic and had in- of an unresolved left breast hematoma. Of note, she durated features with areas of active bleeding. Initially, had a history of left breast inltrating ductal carcinoma no discrete underlying mass was identied on physical that was Her-2/Neu negative with estrogen and proges- examination. Areas of peau de orange surrounded the terone receptor positivity seven years prior. She had lesion. She had no palpable lymphadenopathy. -
The Acetabular Blood Supply: Implications for Periacetabular Osteotomies
View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by RERO DOC Digital Library Surg Radiol Anat (2003) 25: 361–367 DOI 10.1007/s00276-003-0149-3 ANATOMIC BASES OF MEDICAL, RADIOLOGICAL AND SURGICAL TECHNIQUES M. Beck Æ M. Leunig Æ T. Ellis Æ J. B. Sledge Æ R. Ganz The acetabular blood supply: implications for periacetabular osteotomies Received: 22 April 2002 / Accepted: 27 February 2003 / Published online: 16 August 2003 Ó Springer-Verlag 2003 Abstract As the popularity of juxta-acetabular osteot- noise, une e´ tude anatomique apre` s injection de latex omies in adults increases, concern arises that such a colore´ ae´ te´ re´ alise´ e. La vascularisation du versant ex- procedure will potentially cause avascular necrosis of the terne du fragment pe´ ri-ace´ tabulaire a e´ te´ e´ tudie´ e sur 16 acetabular fragment. In order to verify the remaining hanches apre` s injection de latex colore´ dans l’aorte ab- vascularization after a Bernese periacetabular osteoto- dominale et celle de son versant interne sur 4 hanches. my, an injection study with colored latex was performed. Pour confirmer les conclusions tire´ es du travail anato- The vascularity of the outside of the periacetabular bone mique, une oste´ otomie pe´ ri-ace´ tabulaire bernoise a e´ te´ was studied in 16 hips after injection of colored latex re´ alise´ e sur deux hanches supple´ mentaires apre` s injec- into the abdominal aorta and the inside in four hips. To tion de latex. Cette e´ tude a montre´ que, par une voie confirm the conclusions drawn from the anatomic study, d’abord de Smith-Petersen modifie´ eetenre´ alisant a Bernese periacetabular osteotomy was performed in l’oste´ otomie a` partir du versant interne du bassin, le two additional hips after latex injection. -
Massachusetts Breastfeeding Resource Guide
Massachusetts Breastfeeding Resource Guide 2008 Edition © 254 Conant Road Weston, MA 02493 781 893-3553 Fax 781 893-8608 www.massbfc.org Massachusetts Breastfeeding Coalition Leadership Chair Board Member Melissa Bartick, MD, MS Lauren Hanley, MD Treasurer Board Member Gwen MacCaughey Marsha Walker, RN, IBCLC NABA, Lactation Associates Clerk Xena Grossman, RD, MPH Board Member Anne Merewood, MPH, IBCLC Board Member Lucia Jenkins, RN, IBCLC La Leche League of MA RI VT 10th edition (2008) Compiled and edited by Rachel Colchamiro, MPH, RD, LDN, CLC and Jan Peabody Cover artwork courtesy of Peter Kuper Funding for the printing and distribution of the Massachusetts Breastfeeding Resource Guide is provided by the Massachusetts Department of Public Health-Bureau of Family and Community Health, Nutrition Division. Permission is granted to photocopy this guide except for the three reprinted articles from the American Academy of Pediatrics and two articles from the American Academy of Family Physicians. Adapted from the Philadelphia Breastfeeding Resource Handbook. hhhhhhhhhhhhhhhhhhhhTable of Contents Organizational statements on breastfeeding…………………………………………………………….2 Breastfeeding and the Use of Human Milk, American Academy of Pediatrics…………………….6 Breastfeeding Position Paper, American Academy of Family Physicians……………………...…19 Breastfeeding initiatives………………………...……………………………………………………...…37 Breastfeeding support and services…………………………………………...………………...…....…39 La Leche League International leaders………….…………………………………………………...….40 Lactation consultants………………………………………………………………………………….…..44 -
The Anatomy of Th-E Blood Vascular System of the Fox ,Squirrel
THE ANATOMY OF TH-E BLOOD VASCULAR SYSTEM OF THE FOX ,SQUIRREL. §CIURUS NlGER. .RUFIVENTEB (OEOEEROY) Thai: for the 009m of M. S. MICHIGAN STATE COLLEGE Thomas William Jenkins 1950 THulS' ifliillifllfllilllljllljIi\Ill\ljilllHliLlilHlLHl This is to certifg that the thesis entitled The Anatomy of the Blood Vascular System of the Fox Squirrel. Sciurus niger rufiventer (Geoffroy) presented by Thomas William Jenkins has been accepted towards fulfillment of the requirements for A degree in MEL Major professor Date May 23’ 19500 0-169 q/m Np” THE ANATOMY OF THE BLOOD VASCULAR SYSTEM OF THE FOX SQUIRREL, SCIURUS NIGER RUFIVENTER (GEOFFROY) By THOMAS WILLIAM JENKINS w L-Ooffi A THESIS Submitted to the School of Graduate Studies of Michigan State College of Agriculture and Applied Science in partial fulfillment of the requirements for the degree of MASTER OF SCIENCE Department of Zoology 1950 \ THESlSfi ACKNOWLEDGMENTS Grateful acknowledgment is made to the following persons of the Zoology Department: Dr. R. A. Fennell, under whose guidence this study was completed; Mr. P. A. Caraway, for his invaluable assistance in photography; Dr. D. W. Hayne and Mr. Poff, for their assistance in trapping; Dr. K. A. Stiles and Dr. R. H. Manville, for their helpful suggestions on various occasions; Mrs. Bernadette Henderson (Miss Mac), for her pleasant words of encouragement and advice; Dr. H. R. Hunt, head of the Zoology Department, for approval of the research problem; and Mr. N. J. Mizeres, for critically reading the manuscript. Special thanks is given to my wife for her assistance with the drawings and constant encouragement throughout the many months of work. -
Diagnostic Issues in Systemic Lupus Erythematosis
266 Postgrad Med J 2001;77:266–285 Postgrad Med J: first published as 10.1136/pmj.77.906.268 on 1 April 2001. Downloaded from SELF ASSESSMENT QUESTIONS Diagnostic issues in systemic lupus erythematosis N Sofat, C Higgens Answers on p 274. A 24 year old woman was diagnosed with sys- (4) What other tests (apart from 24 hour urine temic lupus erythematosis (SLE) based on a creatinine clearance) are available to measure few months’ history of a photosensitive skin the glomerular filtration rate? rash, predominantly on her face, arthralgia The patient had a 24 hour urinary protein col- involving both hands and wrists, a positive lection, which showed a 24 hour protein measure- antinuclear antibody (ANA) test and a raised ment of 1.8 g. There was no evidence of cellular antinative double stranded DNA antibody casts on urine microscopy. Her blood results were binding level. She was treated with oral as below (normal values are in parentheses): hydroxychloroquine 400 mg daily and short x Sodium 134 mmol/l (135–145) courses of prednisolone during flare-ups. x Potassium 4.5 mmol/l (3.5–5.0) She was reviewed in clinic for her regular x Urea 7.0 mmol/l (2.5–6.7) follow up appointment when she was found to x Creatinine 173 µmol/l (70–115) be hypertensive on repeated measurements of x Haemoglobin 108 g/l (115–160) her blood pressure, an average value being x White cell count 4.5 × 109/l (4.0–11.0) 150/90 mm Hg. She was also urine dipstick x Platelets 130 × 109/l (150–400) positive for blood and protein. -
Research Day 2021 Program
Western Michigan University ScholarWorks at WMU Research Day WMU Homer Stryker M.D. School of Medicine 2021 Research Day 2021 Program Western Michigan University Homer Stryker M.D. School of Medicine Follow this and additional works at: https://scholarworks.wmich.edu/medicine_research_day Part of the Life Sciences Commons, and the Medicine and Health Sciences Commons WMU ScholarWorks Citation Homer Stryker M.D. School of Medicine, Western Michigan University, "Research Day 2021 Program" (2021). Research Day. 298. https://scholarworks.wmich.edu/medicine_research_day/298 This Abstract is brought to you for free and open access by the WMU Homer Stryker M.D. School of Medicine at ScholarWorks at WMU. It has been accepted for inclusion in Research Day by an authorized administrator of ScholarWorks at WMU. For more information, please contact [email protected]. th 38 Annual Kalamazoo Community Medical and Health Sciences Virtual Research Day Wednesday, April 21, 2021 8:00 a.m. – 12:00 p.m. TABLE OF CONTENTS INTRODUCTION ........................................................................................................... 4 KEYNOTE SPEAKER.................................................................................................... 6 SCHEDULE ..................................................................................................................... 7 ORAL PRESENTATIONS ............................................................................................. 8 ORAL ABSTRACTS .................................................................................................... -
PERIPHERAL VASCULATURE Average Vessel Diameter
PERIPHERAL VASCULATURE Average Vessel Diameter A Trio of Technologies. Peripheral Embolization Solutions A Single Solution. Fathom™ Steerable Guidewires Total Hypotube Tip Proximal/ UPN Length (cm) Length (cm) Length (cm) Distal O.D. Hepatic, Gastro-Intestinal and Splenic Vasculature 24 8-10 mm Common Iliac Artery 39 2-4 mm Internal Pudendal Artery M00150 900 0 140 10 10 cm .016 in 25 6-8 mm External Iliac Artery 40 2-4 mm Middle Rectal M00150 901 0 140 20 20 cm .016 in 26 4-6 mm Internal Iliac Artery 41 2-4 mm Obturator Artery M00150 910 0 180 10 10 cm .016 in 27 5-8 mm Renal Vein 42 2-4 mm Inferior Vesical Artery 28 43 M00150 911 0 180 20 20 cm .016 in 15-25 mm Vena Cava 2-4 mm Superficial Epigastric Artery 29 44 M00150 811 0 200 10 10 cm pre-shaped .014 in 6-8 mm Superior Mesenteric Artery 5-8 mm Femoral Artery 30 3-5 mm Inferior Mesenteric Artery 45 2-4 mm External Pudendal Artery M00150 810 0 200 10 10 cm .014 in 31 1-3 mm Intestinal Arteries M00150 814 0 300 10 10 cm .014 in 32 Male 2-4 mm Superior Rectal Artery A M00150 815 0 300 10 10 cm .014 in 33 1-3 mm Testicular Arteries 1-3 mm Middle Sacral Artery B 1-3 mm Testicular Veins 34 2-4 mm Inferior Epigastric Artery Direxion™ Torqueable Microcatheters 35 2-4 mm Iliolumbar Artery Female 36 2-4 mm Lateral Sacral Artery C 1-3 mm Ovarian Arteries Usable 37 D UPN Tip Shape RO Markers 3-5 mm Superior Gluteal Artery 1-3 mm Ovarian Veins Length (cm) 38 2-4 mm Inferior Gluteal Artery E 2-4 mm Uterine Artery M001195200 105 Straight 1 M001195210 130 Straight 1 M001195220 155 Straight 1 Pelvic -
The Nutrition and Food Web Archive Medical Terminology Book
The Nutrition and Food Web Archive Medical Terminology Book www.nafwa. -
Head & Neck Surgery Course
Head & Neck Surgery Course Parapharyngeal space: surgical anatomy Dr Pierfrancesco PELLICCIA Pr Benjamin LALLEMANT Service ORL et CMF CHU de Nîmes CH de Arles Introduction • Potential deep neck space • Shaped as an inverted pyramid • Base of the pyramid: skull base • Apex of the pyramid: greater cornu of the hyoid bone Introduction • 2 compartments – Prestyloid – Poststyloid Anatomy: boundaries • Superior: small portion of temporal bone • Inferior: junction of the posterior belly of the digastric and the hyoid bone Anatomy: boundaries Anatomy: boundaries • Posterior: deep fascia and paravertebral muscle • Anterior: pterygomandibular raphe and medial pterygoid muscle fascia Anatomy: boundaries • Medial: pharynx (pharyngobasilar fascia, pharyngeal wall, buccopharyngeal fascia) • Lateral: superficial layer of deep fascia • Medial pterygoid muscle fascia • Mandibular ramus • Retromandibular portion of the deep lobe of the parotid gland • Posterior belly of digastric muscle • 2 ligaments – Sphenomandibular ligament – Stylomandibular ligament Aponeurosis and ligaments Aponeurosis and ligaments • Stylopharyngeal aponeurosis: separates parapharyngeal spaces to two compartments: – Prestyloid – Poststyloid • Cloison sagittale: separates parapharyngeal and retropharyngeal space Aponeurosis and ligaments Stylopharyngeal aponeurosis Muscles stylohyoidien Stylopharyngeal , And styloglossus muscles Prestyloid compartment Contents: – Retromandibular portion of the deep lobe of the parotid gland – Minor or ectopic salivary gland – CN V branch to tensor -
ARPKD): Kidney-Related and Non-Kidney-Related Phenotypes
Pediatr Nephrol (2014) 29:1915–1925 DOI 10.1007/s00467-013-2634-1 EDUCATIONAL REVIEW Clinical manifestations of autosomal recessive polycystic kidney disease (ARPKD): kidney-related and non-kidney-related phenotypes Rainer Büscher & Anja K. Büscher & Stefanie Weber & Julia Mohr & Bianca Hegen & Udo Vester & Peter F. Hoyer Received: 26 April 2013 /Revised: 5 September 2013 /Accepted: 6 September 2013 /Published online: 10 October 2013 # IPNA 2013 Abstract Autosomal recessive polycystic kidney disease disease. In this review we focus on common and uncommon (ARPKD), although less frequent than the dominant form, is kidney-related and non-kidney-related phenotypes. Clinical a common, inherited ciliopathy of childhood that is caused by management of ARPKD patients should include consideration mutations in the PKHD1-gene on chromosome 6. The charac- of potential problems related to these manifestations. teristic dilatation of the renal collecting ducts starts in utero and can present at any stage from infancy to adulthood. Renal Keywords ARPKD . Extrarenal manifestation . Children . insufficiency may already begin in utero and may lead to early Hepatic fibrosis . Portal hypertension . Caroli’ssyndrome abortion or oligohydramnios and lung hypoplasia in the new- born. However, there are also affected children who have no evidence of renal dysfunction in utero and who are born with Introduction normal renal function. Up to 30 % of patients die in the perinatal period, and those surviving the neonatal period reach Autosomal recessive polycystic kidney disease (ARPKD) be- end stage renal disease (ESRD) in infancy, early childhood or longs to the family of cilia-related disorders and is an important adolescence. In contrast, some affected patients have been inherited disease with distinct clinical features and genetics. -
Emergencies in the Treatment of Wandering Spleen Osher Cohen MD1, Arthur Baazov MD1, Inbal Samuk MD1, Michael Schwarz MD2, Dragan Kravarusic MD1 and Enrique Freud MD1
ORIGINAL ARTICLES ,0$-ǯ92/20ǯ-81(2018 Emergencies in the Treatment of Wandering Spleen Osher Cohen MD1, Arthur Baazov MD1, Inbal Samuk MD1, Michael Schwarz MD2, Dragan Kravarusic MD1 and Enrique Freud MD1 1Departments of Pediatric and Adolescent Surgery and 2Pediatric Radiology, Schneider Children’s Medical Center of Israel, Petach Tikva, Israel, affiliated with Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel and nonspecific clinical presentation [2], making diagnosis ABSTRACT: Background: Wandering spleen is a rare entity that may pose difficult and the potential for a delayed diagnosis high [3]. a surgical emergency following torsion of the splenic vessels, Torsion of the splenic vessels has been described in 64% mainly because of a delayed diagnosis. Complications after of children with wandering spleen [4,5]. The splenic veins surgery for wandering spleen may necessitate emergency are the first vessels compromised because of their lower pres- treatment. sure [6], causing splenic engorgement and capsule stretching. Objectives: To describe the clinical course and treatment for Accordingly, abdominal pain, which can be acute, recurrent, children who underwent emergency surgeries for wandering or chronic, is the most common clinical presentation [7]. spleen at a tertiary pediatric medical center over a 21 year Progression of the torsion may lead to ischemic injury to the period and to indicate the pitfalls in diagnosis and treatment spleen and ultimately splenic necrosis [1]. as reflected by our experience and in the literature. Surgery is considered the only safe treatment for wander- Methods: The database of a tertiary pediatric medical center ing spleen [8], although there are a few reports on the use of was searched retrospectively for all children who underwent conservative methods [9].