Issue 69 of the Genetics Society Newsletter
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From the President's Desk
JAN/FEB 2006 From the President’s desk: 2006, the 75th anniversary of the Genetics Society of America, will be marked by a number of initiatives to reinvigorate the Society’s mission of promoting research and education in genetics. A highlight was the recently held GSA sponsored conference, “Genetic Analysis: From Model Organisms to Human Biology” in San Diego from January 5-7. This conference emphasized the importance of model organism research by illustrating the crucial contributions to human biology resulting from discoveries in these organisms. The National Institutes of Health (NIH) supported this conference both financially and by participation of key NIH administrators, including Jeremy M. Berg, director of the National Institute of General Medical Sciences. In addition to the superb science talks by international leaders the MOHB conference showcased other important and new GSA initiatives including education, public policy advocacy, graduate student support and recognition of outstanding model organism geneticists. Robin Wright, Education Committee chair, led a round table discussion on undergraduate education and the Joint Steering Committee for Public Policy and the Congressional Liaison Committee sponsored a session on science advocacy and public policy. There was a mentor lunch to support graduate students and postdocs in the next steps of their careers, and the three GSA medals were presented during the banquet, with Victor Ambros receiving the GSA Medal, Fred Sherman the Beadle Award, and Masatoshi Nei the Morgan Award. (For research highlights at the meeting, see pages 6 and 7 of this issue.) The 75th anniversary will also usher in changes to our society’s journal, GENETICS. -
Nuclear DNA Analyses in Genetic Studies of Populations: Practice, Problems and Prospects
Molecular Ecology (2003) 12, 563–584 INVITEDBlackwell Publishing Ltd. REVIEW Nuclear DNA analyses in genetic studies of populations: practice, problems and prospects DE-XING ZHANG* and GODFREY M. HEWITT† *State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, 19 Zhongguancun Road, Beijing 100080, PR China, †School of Biological Sciences, University of East Anglia, Norwich NR4 7TJ, UK Abstract Population-genetic studies have been remarkably productive and successful in the last dec- ade following the invention of PCR technology and the introduction of mitochondrial and microsatellite DNA markers. While mitochondrial DNA has proven powerful for genea- logical and evolutionary studies of animal populations, and microsatellite sequences are the most revealing DNA markers available so far for inferring population structure and dynamics, they both have important and unavoidable limitations. To obtain a fuller picture of the history and evolutionary potential of populations, genealogical data from nuclear loci are essential, and the inclusion of other nuclear markers, i.e. single copy nuclear poly- morphic (scnp) sequences, is clearly needed. Four major uncertainties for nuclear DNA analyses of populations have been facing us, i.e. the availability of scnp markers for carry- ing out such analysis, technical laboratory hurdles for resolving haplotypes, difficulty in data analysis because of recombination, low divergence levels and intraspecific multi- furcation evolution, and the utility of scnp markers for addressing population-genetic ques- tions. In this review, we discuss the availability of highly polymorphic single copy DNA in the nuclear genome, describe patterns and rate of evolution of nuclear sequences, sum- marize past empirical and theoretical efforts to recover and analyse data from scnp markers, and examine the difficulties, challenges and opportunities faced in such studies. -
Genetics Society News
July 2008 . ISSUE 59 GENETICS SOCIETY NEWS www.genetics.org.uk IN THIS ISSUE Genetics Society News is edited by Steve Russell. Items for future issues should be sent to Steve Russell, preferably by email to • Genetics Society Epigenetics Meeting [email protected], or hard copy to Department of Genetics, • Genetics Society Sponsored Meetings University of Cambridge, Downing Street, Cambridge CB2 3EH. The Newsletter is published twice a year, with copy dates of 1st June and • Travel, Fieldwork and Studentship Reports 26th November. • John Evans: an Appreciation Cocoons of the parasitoid wasp Cotesia vestalis on cabbage leaf in Taiwan. From the • Twelve Galton Lectures fieldwork report by Jetske G. de Boer on page 36. • My Favourite Paper A WORD FROM THE EDITOR A word from the editor ow soon until the $1000 based on the results of tests we genome is actually with barely understand! Here in the Hus and individual UK there is currently a sequencing is widespread? The moratorium, adhered to by publication of increasing most insurers, on the use of numbers of individual human genetic testing information for genome sequences suggests assessing life insurance that we should start to consider applications. It is important some of the implications that this remains in place and associated with the availability its effectiveness is reviewed of personal genetic well before the current information. In this issue we moratorium expires in 2011. present two articles reflecting The Human Genetics on his issue: a report from a Commission Genetics Society sponsored (http://www.hgc.gov.uk) meeting recently held in monitor issues relating to Cambridge organised by The genetic discrimination in the Triple Helix, an international UK and are a point of contact undergraduate organisation, as for those with any concerns in the Millennium Technology Prize. -
1 Genomic Analysis of Family Data Reveals Additional Genetic Effects On
bioRxiv preprint doi: https://doi.org/10.1101/106203; this version posted February 6, 2017. The copyright holder for this preprint (which was not certified by peer review) is the author/funder. All rights reserved. No reuse allowed without permission. Genomic analysis of family data reveals additional genetic effects on intelligence and personality W. David Hill1,2*†, Ruben C. Arslan3,4†, Charley Xia†5, Michelle Luciano1,2, Carmen Amador5, Pau Navarro5, Caroline Hayward5, Reka Nagy5, David J. Porteous1,6,8, Andrew M. McIntosh1,9, Ian J. Deary1,2, Chris S. Haley5,10, and Lars Penke1,3,4 1 Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, 7 George Square, Edinburgh EH8 9JZ, UK 2 Department of Psychology, University of Edinburgh, 7 George Square, Edinburgh, EH8 9JZ, UK 3 Georg Elias Müller Institute of Psychology, Georg August University Göttingen, Germany 4 Leibniz ScienceCampus Primate Cognition, Göttingen, Germany 5 MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK 6 Generation Scotland, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK 8 Medical Genetics Section, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh 9 Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh EH10 5HF 10 The Roslin Institute and Royal (Dick) School of Veterinary Sciences, University of Edinburgh, UK * Corresponding author † These authors contributed equally Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, 7 George Square, Edinburgh EH8 9JZ, UK, T: +44 (131) 650 8405, E: [email protected] 1 bioRxiv preprint doi: https://doi.org/10.1101/106203; this version posted February 6, 2017. -
Papers Will Be Uploaded in Due Course
THE UNIVERSITY OF EDINBURGH BUSINESS FOR MEETING OF THE UNIVERSITY COURT to be held in the Raeburn Room, Old College on Monday, 9 December 2013 at 2.00 p.m. A buffet lunch will be available at 1.00 p.m. in the Lord Provost Elder Room, Old College This meeting of Court will be preceded by a presentation on the Research Excellence Framework (REF2014) delivered by Mrs Tracey Slaven, Deputy Secretary, Strategic Planning. A FORMAL BUSINESS 1. Minute of the meeting held on 4 November 2013 A1 2. Senate Assessor A2 B PRINCIPAL'S BUSINESS 1. Principal’s Communications B1 2. Vice-Principal update B2 C SUBSTANTIVE ITEMS 1. Report of the Finance and General Purposes Committee .1 Comments on the Report of the Central Management Group C1.1 .2 Report on Other Items C1.2 2. EUSA President’s Report C2 3. Risk Management Committee year end report C3 4. Risk Management – post year end Assurance Statement C4 5. Audit Committee Annual Report C5 6. Reports and Financial Statements .1 Annual Report and Accounts for year ended 31 July 2013 C6.1 .2 Letter of Representation C6.2 .3 Review of 2012/2013 Outturn versus Forecast C6.3 7. 2014-2017 Draft Outcome Agreement C7 8. Strategic Plan: Targets and KPIs Progress Report C8 9. Annual Review 2012-2013 C9 10. Report from Remuneration Committee C10 11. Report from Knowledge Strategy Committee C11 D ITEMS FOR FORMAL APPROVAL OR NOTE 1. Draft Resolutions D1 2. Risk Management Committee – Terms of Reference D2 3. Donations and Legacies D3 4. -
Issue 84 of the Genetics Society Newsletter
JANUARY 2021 | ISSUE 84 GENETICS SOCIETY NEWS In this issue The Genetics Society News is edited by • Non-canonical Careers: Thinking Outside the Box of Academia and Industry Margherita Colucci and items for future • Celebrating the 35th anniversary of DNA fingerprinting issues can be sent to the editor by email • Genetics Society Summer Studentship Workshop 2020 to [email protected]. • 2020 Heredity best student-led paper prize winners The Newsletter is published twice a year, • Industrious Science: interview with Dr Paul Lavin with copy dates of July and January. Celebrating students’ achievements: 2020 Genetics Society Summer Studentship Workshop, 2020 Heredity best student-led paper prize. Page 30 A WORD FROM THE EDITOR A word from the editor Welcome to Issue 84 elcome to the latest issue of the Thinking Outside the Box of WGenetics Society Newsletter! Academia and Industry”. This little This issue is packed with great news vade mecum for careers in genetics of achievements and good science. The collects inspiring interviews led first Genetics Society virtual workshop by our very own Postgraduate for the 2020 Summer studentship saw Representative, Emily Baker. In exceptional contributions from the Emily’s words, these experiences attending students. You can read more “demonstrate how a PhD in genetics about participants’ experiences in the can be a platform for a career in just interviews with the talk’s winners in about anything. Pursuing a career the Feature section. in academia, industry, publishing or science communication could be for Many more prizes were awarded: you, but so could many others. Why Heredity journal announced the not take a career path less travelled 2020 Heredity best student-led paper by, it might make all the difference?” winners, and James Burgon’s Heredity podcast dedicated an episode to the Enjoy! first prize winner, with insights from Best wishes, Heredity Editor-in-Chief, Barbara Margherita Colucci Mable. -
The Genetic Legacy of the Quaternary Ice Ages
review article The genetic legacy of the Quaternary ice ages Godfrey Hewitt School of Biological Sciences, University of East Anglia, Norwich NR4 7TJ, UK ............................................................................................................................................................................................................................................................................ Global climate has fluctuated greatly during the past three million years, leading to the recent major ice ages. An inescapable consequence for most living organisms is great changes in their distribution, which are expressed differently in boreal, temperate and tropical zones. Such range changes can be expected to have genetic consequences, and the advent of DNA technology provides most suitable markers to examine these. Several good data sets are now available, which provide tests of expectations, insights into species colonization and unexpected genetic subdivision and mixture of species. The genetic structure of human populations may be viewed in the same context. The present genetic structure of populations, species and communities has been mainly formed by Quaternary ice ages, and genetic, fossil and physical data combined can greatly help our understanding of how organisms were so affected. The study of palaeoclimates is a particularly active research field that These severe climatic oscillations produced great changes in species is producing much data and increasingly coherent explanations. distributions, and these have been described in some detail, particularly The Earth’s climate became cooler through the Tertiary (65 million from the fossil records of pollen and beetles in Europe and North years (Myr)) with frequent oscillations that increased in amplitude America1,9. Species went extinct over large parts of their range, some and lead to the series of major ice ages of the Quaternary (2.4 Myr to dispersed to new locations, some survived in refugia and then the present). -
100 Years of Genetics
Heredity (2019) 123:1–3 https://doi.org/10.1038/s41437-019-0230-2 EDITORIAL 100 years of genetics Alison Woollard1 Received: 27 April 2019 / Accepted: 28 April 2019 © The Genetics Society 2019 The UK Genetics Society was founded on 25 June 1919 and “biometricians”; the Genetical Society was very much a this special issue of Heredity, a journal owned by the society of Mendelians. Remarkably, 16 of the original 87 Society, celebrates a century of genetics from the perspec- members were women—virtually unknown in scientific tives of nine past (and present) presidents. societies at the time. Saunders was a vice president from its The founding of the Genetical Society (as it was then beginning and its 4th president from 1936–1938. Perhaps known) is often attributed to William Bateson, although it the new, and somewhat radical, ideas of “genetics” pre- was actually the brain child of Edith Saunders. The enthu- sented a rare opportunity for women to engage in research siasm of Saunders to set up a genetics association is cited in because the field lacked recognition in universities, and was the anonymous 1916 report “Botany at the British Asso- therefore less attractive to men. 1234567890();,: 1234567890();,: ciation”, Nature, 98, 2456, p. 238. Furthermore, the actual Bateson and Saunders (along with Punnett) were also founding of the Society in 1919 “largely through the energy influential in the field of linkage analysis (“partial coupling” as of Miss E.R Saunders” is reported (anonymously) in they referred to it at the time), having made several observa- “Notes”, Nature, 103, 2596, p. -
Issue 82 of the Genetics Society Newsletter
JANUARY 2020 | ISSUE 82 GENETICS SOCIETY NEWS In this issue The Genetics Society News is edited by Margherita Colucci and items for future • Medal and Prize Lecture Announcements issues can be sent to the editor by email • “A Century of Genetics” conference to [email protected]. • Celebrating the centenary of Fisher 1918 The Newsletter is published twice a year, • Research and travel grant reports with copy dates of July and January. Speakers’ dinner at the “A Century of Genetics” conference, November 2019, Edinburgh. (Photo by Douglas Vernimmen) A WORD FROM THE EDITOR A word from the editor Welcome to Issue 82 elcome to the latest issue of reports in the Sectional Interest Wthe GenSoc Newsletter and Groups: Reports section. my first steps (pages?) as new editor. And why not (re)discovering another I am eager to start this journey with great milestone such as the publishing you through the latest Genetics of Fisher’s 1918 paper, “The correlation Society achievements and genetics between relatives on the supposition news! I would like to thank all of Mendelian inheritance”, recently GenSoc committee for giving me this reaching its centenary recurrence? opportunity. I am sure you will greatly enjoy the In this issue, I will bring you back to report in the Features section. the inspiring and lively atmosphere Enjoy! of the GenSoc meeting ‘A Century of Genetics’ in Edinburgh (November Best wishes, 2019) - a really big thanks to all of those Margherita Colucci who kindly contributed. Many Sectional Interest groups have been very active: you will find their In this issue, I will bring you back to the inspiring and lively atmosphere of the GenSoc meeting “A Century of Genetics” in Edinburgh (November 2019) - a really big thanks to all of those who kindly contributed. -
Perspectives
Copyright Ó 2007 by the Genetics Society of America Perspectives Anecdotal, Historical and Critical Commentaries on Genetics Edited by James F. Crow and William F. Dove R. A. Fisher’s 1943 Unravelling of the Rhesus Blood-Group System A. W. F. Edwards1 Gonville and Caius College, Cambridge CB2 1TA, United Kingdom VEN if R. A. Fisher’s elucidation of the human blood- binatorial skills and his relations with A. S. Wiener, and E group system Rhesus in terms of the three linked to add a personal coda. It is best to take first the diagram loci C, D, and E had not proved to be substantially (Figure 1) from Fisher (1947) because it explains the correct, it would still have been an outstanding example relationship between the original Rhesus notation and of the power of analytical thought to unravel a complex that proposed by Fisher. As Fisher writes, ‘‘We may repre- array of genetical data. In fact, as a recent review relates sent the eight heritable antigen complexes geometrically (Avent et al. 2006), D is one gene (carrying the D anti- as the corners of a cube, while the six elementary antigens gen) and C and E are different splicing forms of another are represented by the faces; each allelomorphic pair of (CE carrying the C or c antigens and the E or e antigens). antigens is then a pair of opposite faces, and the three Fisher’s solution is recognizable beneath the modern faces meeting in any point specify the antigens in each molecular detail. complex.’’ (Ry) and (CdE) are in parentheses because The story of the unravelling of the Rhesus puzzle is the anti-d antibody had not yet been discovered (nor has told in chapter 13 of Joan Fisher Box’s R. -
Genetics Society of America
Genetics Society of America 1992 Records, Proceedings and Reports Published as supplementary material in GENETICS, Volume 131 Prepared by The Secretary Shirleen Roeder Department of Biology Yale University New Haven, Connecticut s2 BOARDS, COMMITTEES AND REPRESENTATIVES FOR 1992 BOARD OF DIRECTORS John C. Lucchesi, President Karen Artzt A. Dale Kaiser, Vice-president Welcome Bender Shirleen Roeder, Secretary Nina V. Fedoroff Carol S. Newlon, Treasurer Barry S. Ganetzky Leland H. Hartwell, Past President Christine Guthrie John W. Drake, Editor H. Robert Horvitz GENETICSEDITORIAL BOARD John W. Drake, Editor Maureen R. Hanson Sally Lyman Allen Robert K. Herman Karen Artzt Alan G. Hinnebusch Douglas E. Berg Richard R. Hudson David Botstein Nancy A. Jenkins John E. Boynton Mark Johnston Anthony H. D. Brown Elizabeth Jones Benjamin Burr Cathy C. Laurie Marian Carlson Wen-Hsiung Li Deborah Charlesworth Trudy F. C. Mackay Peter Cherbas Patricia J. Pukkila Arthur Chovnick Trudi Schiipbach Andrew G. Clark William F. Sheridan Thomas W. Cline Michael J. Simmons Rowland H. Davis Montgomery Slatkin Robin E. Denell Gerald R. Smith Norman R. Drinkwater Steven D. Tanksley Walter F. Eanes Elizabeth Thompson Victoria G. Finnerty Bruce S. Weir Margaret T. Fuller Fred Winston Roger E. Ganschow ADMINISTRATIVE OFFICE Elaine Strass, Executive Director Barbara Abbott, Publicat~nsAssistant/ASHG Membership Coordinator Sharon Adler, Accounting Assistant Judy Ashton, Oflce Coordinator Candis Galkin, Accounting Assistant Gloria Garber, Membership and Meetings Assistant Karen Gould, Comptroller/Manager of Administration Margot Kiley, GSA Membership Coordinator Krista Koziol, Publications Manager Anne Marie Langevin, GSA Meetings Manager Marsha Ryan, ASHG Meetings Manager Jane Salomon, ASHG Special Projects Manager COMMITTEES Leland H. -
BSCB Newsletter 2019A:BSCB Aut2k7
2019 BSCB Magazine BRITISH SOCIETY FOR CELL BIOLOGY 2019 CONTENTS BSCB Magazine News 2 Book reviews 8 Features 9 Meeting Reports 21 Summer students 25 Society Business 32 Editorial Front cover: microscopic Welcome to the 2019 BSCB Magazine! This year Mustafa Aydogan (University of Oxford), as well as to structure of pectoral fin and Susana and Stephen are filling in for our Newsletter BSCB postdoc poster of the year winners Dr Anna hypaxial muscles of a zebrafish Editor Ann Wheeler. We hope you will enjoy this Caballe (University of Oxford) and Dr Agata Gluszek- Danio rerio larvae at four days year’s magazine! Kustusz (University of Edinburgh). post fertilization. The immunostaining highlights the This year we had a number of fantastic one day In 2019, we will have our jointly BSCB-BSDB organization of fast (red) and meetings sponsored by BSCB. These focus meetings Spring meeting at Warwick University from 7th–10th slow (green) myosins. All nuclei are great way to meet and discuss your science with April, organised by BSCB members Susana Godinho are highlighted in blue (hoechst). experts in your field and to strengthen your network of and Vicky Sanz-Moreno. The programme for this collaborators within the UK. You can read more about meeting, which usually provides a broad spectrum of these meetings in the magazine. If you have an idea themes, has a focus on cancer biology: cell for a focus one day meeting, check how to apply for migration/invasion, organelle biogenesis, trafficking, funding on page 4. Our ambassadors have also been cell-cell communication.