Drug Discovery and Evaluation: Methods in Clinical Pharmacology

H.G. Vogel, J. Maas, A. Gebauer (Eds.) Drug Discovery and Evaluation: Methods in Clinical Pharmacology

▶ These volumes are a landmark in the continuously changing world of drugs ▶ An easy-to-use, method-oriented overview on all aspects of clinical pharmacology ▶ Essential reading for pharmacologists, physicians, medicinal chemists and pharmacists at research institutes and in industry ▶ Of use for governmental institutions and committees working on official guidelines for drug evaluation worldwide

Drug Discovery and Evaluation has become a more and more difficult, expensive and time-consuming process. The effect of a new compound has to be detected by in vitro and 2011, 138 illus. eReference. in vivo methods of pharmacology. The activity spectrum and the potency compared to existing drugs have to be determined.

As these processes can be divided up stepwise we have designed a book series "Drug Discovery and Evaluation" in the form of a recommendation document. The methods to detect drug targets are described in the first volume of this series "Pharmacological Assays" comprising classical methods as well as new technologies. Before going to man, the most suitable compound has to be selected by pharmacokinetic studies and experiments in toxicology. These preclinical methods are described in the second volume „Safety and Pharmacokinetic Assays". Only then are first studies in human beings allowed. Print (Book) Special rules are established for Phase I studies. Clinical pharmacokinetics are performed ▶ 599,99 € | £549.99 | $749.99 in parallel with human studies on tolerability and therapeutic effects. Special studies ▶ **641,99 € (D) | 659,99 € (A) | according to various populations and different therapeutic indications are necessary. CHF 707.50 These items are covered in the third volume: „Methods in Clinical Pharmacology". eReference ▶ 499,99 € | £449.99 | $599.99 ▶ **534,99 € (D) | 499,99 € (A) | CHF 589.50

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