crystals Article Potential Therapeutic Effects of New Ruthenium (III) Complex with Quercetin: Characterization, Structure, Gene Regulation, and Antitumor and Anti-Inflammatory Studies (RuIII/Q Novel Complex Is a Potent Immunoprotective Agent) Moamen S. Refat 1,*, Reham Z. Hamza 2,* , Abdel Majid A. Adam 1, Hosam A. Saad 1,* , Adil A. Gobouri 1, Fawziah A. Al-Salmi 2, Tariq A. Altalhi 1 and Samy M. El-Megharbel 1 1 Department of Chemistry, Faculty of Science, Main Campus, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia;
[email protected] (A.M.A.A.);
[email protected] (A.A.G.);
[email protected] (T.A.A.);
[email protected] (S.M.E.-M.) 2 Biology Department, Faculty of Science, Main Campus, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia;
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[email protected] (R.Z.H.);
[email protected] (H.A.S.) Citation: Refat, M.S.; Hamza, R.Z.; Abstract: The aim of this study was to evaluate the antioxidant and anti-inflammatory effects of the Adam, A.M.A.; Saad, H.A.; Gobouri, III new [Ru(Q)(Cl)2(H2O)2] complex (Ru /Q). A new vital complex containing quercetin flavonoid A.A.; Al-Salmi, F.A.; Altalhi, T.A.; compound (Q) with ruthenium (III) ions was synthesized. The molar conductivity of the RuIII/Q El-Megharbel, S.M. Potential complex was measured in dimethylsulfoxide (DMSO) with value 12 (W−1 mol−1 cm−1, indicating Therapeutic Effects of New their non-electrolytic nature.