Anatomy of Cerebral Hemispheres
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Network Architecture of the Cerebral Nuclei (Basal Ganglia) Association and Commissural Connectome
Network architecture of the cerebral nuclei (basal ganglia) association and commissural connectome Larry W. Swansona,1, Olaf Spornsb, and Joel D. Hahna aDepartment of Biological Sciences, University of Southern California, Los Angeles, CA 90089; and bDepartment of Psychological and Brain Sciences, Indiana University, Bloomington, IN 47405 Contributed by Larry W. Swanson, August 10, 2016 (sent for review July 18, 2016; reviewed by Ann M. Graybiel and Liqun Luo) The cerebral nuclei form the ventral division of the cerebral hemi- same basic strategy and methodology applied to the rat cerebral sphere and are thought to play an important role in neural systems cortical association macroconnectome (10) but with additional an- controlling somatic movement and motivation. Network analysis alytical approaches and curation tools. In this approach a macro- was used to define global architectural features of intrinsic cerebral connection is defined as a monosynaptic axonal (directed, from/to) nuclei circuitry in one hemisphere (association connections) and connection between two nervous system gray matter regions or between hemispheres (commissural connections). The analysis was between a gray matter region and another part of the body (such as based on more than 4,000 reports of histologically defined axonal a muscle) (11, 12). All 45 gray matter regions of the cerebral nuclei connections involving all 45 gray matter regions of the rat cerebral on each side of the brain were included in the analysis. The goal of nuclei and revealed the existence of four asymmetrically intercon- this analysis was to provide global, high-level, design principles of nected modules. The modules form four topographically distinct intrinsic cerebral nuclei circuitry as a framework for more detailed research at the meso-, micro-, and nanolevels of analysis (13). -
Distance Learning Program Anatomy of the Human Brain/Sheep Brain Dissection
Distance Learning Program Anatomy of the Human Brain/Sheep Brain Dissection This guide is for middle and high school students participating in AIMS Anatomy of the Human Brain and Sheep Brain Dissections. Programs will be presented by an AIMS Anatomy Specialist. In this activity students will become more familiar with the anatomical structures of the human brain by observing, studying, and examining human specimens. The primary focus is on the anatomy, function, and pathology. Those students participating in Sheep Brain Dissections will have the opportunity to dissect and compare anatomical structures. At the end of this document, you will find anatomical diagrams, vocabulary review, and pre/post tests for your students. The following topics will be covered: 1. The neurons and supporting cells of the nervous system 2. Organization of the nervous system (the central and peripheral nervous systems) 4. Protective coverings of the brain 5. Brain Anatomy, including cerebral hemispheres, cerebellum and brain stem 6. Spinal Cord Anatomy 7. Cranial and spinal nerves Objectives: The student will be able to: 1. Define the selected terms associated with the human brain and spinal cord; 2. Identify the protective structures of the brain; 3. Identify the four lobes of the brain; 4. Explain the correlation between brain surface area, structure and brain function. 5. Discuss common neurological disorders and treatments. 6. Describe the effects of drug and alcohol on the brain. 7. Correctly label a diagram of the human brain National Science Education -
Anatomy of the Temporal Lobe
Hindawi Publishing Corporation Epilepsy Research and Treatment Volume 2012, Article ID 176157, 12 pages doi:10.1155/2012/176157 Review Article AnatomyoftheTemporalLobe J. A. Kiernan Department of Anatomy and Cell Biology, The University of Western Ontario, London, ON, Canada N6A 5C1 Correspondence should be addressed to J. A. Kiernan, [email protected] Received 6 October 2011; Accepted 3 December 2011 Academic Editor: Seyed M. Mirsattari Copyright © 2012 J. A. Kiernan. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Only primates have temporal lobes, which are largest in man, accommodating 17% of the cerebral cortex and including areas with auditory, olfactory, vestibular, visual and linguistic functions. The hippocampal formation, on the medial side of the lobe, includes the parahippocampal gyrus, subiculum, hippocampus, dentate gyrus, and associated white matter, notably the fimbria, whose fibres continue into the fornix. The hippocampus is an inrolled gyrus that bulges into the temporal horn of the lateral ventricle. Association fibres connect all parts of the cerebral cortex with the parahippocampal gyrus and subiculum, which in turn project to the dentate gyrus. The largest efferent projection of the subiculum and hippocampus is through the fornix to the hypothalamus. The choroid fissure, alongside the fimbria, separates the temporal lobe from the optic tract, hypothalamus and midbrain. The amygdala comprises several nuclei on the medial aspect of the temporal lobe, mostly anterior the hippocampus and indenting the tip of the temporal horn. The amygdala receives input from the olfactory bulb and from association cortex for other modalities of sensation. -
Toward a Common Terminology for the Gyri and Sulci of the Human Cerebral Cortex Hans Ten Donkelaar, Nathalie Tzourio-Mazoyer, Jürgen Mai
Toward a Common Terminology for the Gyri and Sulci of the Human Cerebral Cortex Hans ten Donkelaar, Nathalie Tzourio-Mazoyer, Jürgen Mai To cite this version: Hans ten Donkelaar, Nathalie Tzourio-Mazoyer, Jürgen Mai. Toward a Common Terminology for the Gyri and Sulci of the Human Cerebral Cortex. Frontiers in Neuroanatomy, Frontiers, 2018, 12, pp.93. 10.3389/fnana.2018.00093. hal-01929541 HAL Id: hal-01929541 https://hal.archives-ouvertes.fr/hal-01929541 Submitted on 21 Nov 2018 HAL is a multi-disciplinary open access L’archive ouverte pluridisciplinaire HAL, est archive for the deposit and dissemination of sci- destinée au dépôt et à la diffusion de documents entific research documents, whether they are pub- scientifiques de niveau recherche, publiés ou non, lished or not. The documents may come from émanant des établissements d’enseignement et de teaching and research institutions in France or recherche français ou étrangers, des laboratoires abroad, or from public or private research centers. publics ou privés. REVIEW published: 19 November 2018 doi: 10.3389/fnana.2018.00093 Toward a Common Terminology for the Gyri and Sulci of the Human Cerebral Cortex Hans J. ten Donkelaar 1*†, Nathalie Tzourio-Mazoyer 2† and Jürgen K. Mai 3† 1 Department of Neurology, Donders Center for Medical Neuroscience, Radboud University Medical Center, Nijmegen, Netherlands, 2 IMN Institut des Maladies Neurodégénératives UMR 5293, Université de Bordeaux, Bordeaux, France, 3 Institute for Anatomy, Heinrich Heine University, Düsseldorf, Germany The gyri and sulci of the human brain were defined by pioneers such as Louis-Pierre Gratiolet and Alexander Ecker, and extensified by, among others, Dejerine (1895) and von Economo and Koskinas (1925). -
Basic Brain Anatomy
Chapter 2 Basic Brain Anatomy Where this icon appears, visit The Brain http://go.jblearning.com/ManascoCWS to view the corresponding video. The average weight of an adult human brain is about 3 pounds. That is about the weight of a single small To understand how a part of the brain is disordered by cantaloupe or six grapefruits. If a human brain was damage or disease, speech-language pathologists must placed on a tray, it would look like a pretty unim- first know a few facts about the anatomy of the brain pressive mass of gray lumpy tissue (Luria, 1973). In in general and how a normal and healthy brain func- fact, for most of history the brain was thought to be tions. Readers can use the anatomy presented here as an utterly useless piece of flesh housed in the skull. a reference, review, and jumping off point to under- The Egyptians believed that the heart was the seat standing the consequences of damage to the structures of human intelligence, and as such, the brain was discussed. This chapter begins with the big picture promptly removed during mummification. In his and works down into the specifics of brain anatomy. essay On Sleep and Sleeplessness, Aristotle argued that the brain is a complex cooling mechanism for our bodies that works primarily to help cool and The Central Nervous condense water vapors rising in our bodies (Aristo- tle, republished 2011). He also established a strong System argument in this same essay for why infants should not drink wine. The basis for this argument was that The nervous system is divided into two major sec- infants already have Central nervous tions: the central nervous system and the peripheral too much moisture system The brain and nervous system. -
01 05 Lateral Surface of the Brain-NOTES.Pdf
Lateral Surface of the Brain Medical Neuroscience | Tutorial Notes Lateral Surface of the Brain 1 MAP TO NEUROSCIENCE CORE CONCEPTS NCC1. The brain is the body's most complex organ. LEARNING OBJECTIVES After study of the assigned learning materials, the student will: 1. Demonstrate the four paired lobes of the cerebral cortex and describe the boundaries of each. 2. Sketch the major features of each cerebral lobe, as seen from the lateral view, identifying major gyri and sulci that characterize each lobe. NARRATIVE by Leonard E. WHITE and Nell B. CANT Duke Institute for Brain Sciences Department of Neurobiology Duke University School of Medicine Overview When you view the lateral aspect of a human brain specimen (see Figures A3A and A102), three structures are usually visible: the cerebral hemispheres, the cerebellum, and part of the brainstem (although the brainstem is not visible in the specimen photographed in lateral view for Fig. 1 below). The spinal cord has usually been severed (but we’ll consider the spinal cord later), and the rest of the subdivisions are hidden from lateral view by the hemispheres. The diencephalon and the rest of the brainstem are visible on the medial surface of a brain that has been cut in the midsagittal plane. Parts of all of the subdivisions are also visible from the ventral surface of the whole brain. Over the next several tutorials, you will find video demonstrations (from the brain anatomy lab) and photographs (in the tutorial notes) of these brain surfaces, and sufficient detail in the narrative to appreciate the overall organization of the parts of the brain that are visible from each perspective. -
The Human Brain Hemisphere Controls the Left Side of the Body and the Left What Makes the Human Brain Unique Is Its Size
About the brain Cerebrum (also known as the The brain is made up of around 100 billion nerve cells - each one cerebral cortex or forebrain) is connected to another 10,000. This means that, in total, we The cerebrum is the largest part of the brain. It is split in to two have around 1,000 trillion connections in our brains. (This would ‘halves’ of roughly equal size called hemispheres. The two be written as 1,000,000,000,000,000). These are ultimately hemispheres, the left and right, are joined together by a bundle responsible for who we are. Our brains control the decisions we of nerve fibres called the corpus callosum. The right make, the way we learn, move, and how we feel. The human brain hemisphere controls the left side of the body and the left What makes the human brain unique is its size. Our brains have a hemisphere controls the right side of the body. The cerebrum is larger cerebral cortex, or cerebrum, relative to the rest of the The human brain is the centre of our nervous further divided in to four lobes: frontal, parietal, occipital, and brain than any other animal. (See the Cerebrum section of this temporal, which have different functions. system. It is the most complex organ in our fact sheet for further information.) This enables us to have abilities The frontal lobe body and is responsible for everything we do - such as complex language, problem-solving and self-control. The frontal lobe is located at the front of the brain. -
Function of Cerebral Cortex
FUNCTION OF CEREBRAL CORTEX Course: Neuropsychology CC-6 (M.A PSYCHOLOGY SEM II); Unit I By Dr. Priyanka Kumari Assistant Professor Institute of Psychological Research and Service Patna University Contact No.7654991023; E-mail- [email protected] The cerebral cortex—the thin outer covering of the brain-is the part of the brain responsible for our ability to reason, plan, remember, and imagine. Cerebral Cortex accounts for our impressive capacity to process and transform information. The cerebral cortex is only about one-eighth of an inch thick, but it contains billions of neurons, each connected to thousands of others. The predominance of cell bodies gives the cortex a brownish gray colour. Because of its appearance, the cortex is often referred to as gray matter. Beneath the cortex are myelin-sheathed axons connecting the neurons of the cortex with those of other parts of the brain. The large concentrations of myelin make this tissue look whitish and opaque, and hence it is often referred to as white matter. The cortex is divided into two nearly symmetrical halves, the cerebral hemispheres . Thus, many of the structures of the cerebral cortex appear in both the left and right cerebral hemispheres. The two hemispheres appear to be somewhat specialized in the functions they perform. The cerebral hemispheres are folded into many ridges and grooves, which greatly increase their surface area. Each hemisphere is usually described, on the basis of the largest of these grooves or fissures, as being divided into four distinct regions or lobes. The four lobes are: • Frontal, • Parietal, • Occipital, and • Temporal. -
Windows to the Brain: Introduction to Neuroanatomy
VA Mid-Atlantic Health Care Network Windows to the Brain: Introduction to Neuroanatomy Overview Planes of Section Radiographic Perspective Major Divisions Cortical Lobes, Gyri & Sulci General Functions Brodmann’s Areas Basal Forebrain Subcortical Structures Symptoms Cerebellum Structures Symptoms Katherine Taber, PhD, FANPA MIRECC Assistant Director - Education Research Health Scientist W.G. “Bill” Hefner VAMC, Salisbury NC Research Professor, Div Biomedical Sciences Edward Via College of Osteopathic Medicine Robin Hurley, MD, FANPA MIRECC Associate Director - Education ACOS/Research and Academic Affairs Service Line W.G. “Bill” Hefner VAMC, Salisbury NC Professor, Psychiatry and Radiology Wake Forest School of Medicine revised September 2019 Source: http://www.mirecc.va.gov/visn6/Tools-Tips.asp Use of text, images and other content are subject to the following terms and conditions: Fair Use Is Permitted Fair use of copyrighted material includes the use for non-commercial educational purposes, such as teaching, scholarship, research, criticism, commentary, news reporting, and other content. Unless otherwise noted, users who wish to download or print text and image files from this Web site for such uses may do so without the VISN 6 MIRECC’s express permission, provided that they comply with the following conditions: The content may only be used for personal, educational or non- commercial purposes; Users must always specifically cite the author(s) and source of the content every time the material is used, as they would for material from any printed work; None of the content may be altered or modified. Warranty By downloading, printing, or otherwise using text and image files from this website, users agree and warrant that they will limit their use of such files to fair use. -
1. Lateral View of Lobes in Left Hemisphere TOPOGRAPHY
TOPOGRAPHY T1 Division of Cerebral Cortex into Lobes 1. Lateral View of Lobes in Left Hemisphere 2. Medial View of Lobes in Right Hemisphere PARIETAL PARIETAL LIMBIC FRONTAL FRONTAL INSULAR: buried OCCIPITAL OCCIPITAL in lateral fissure TEMPORAL TEMPORAL 3. Dorsal View of Lobes 4. Ventral View of Lobes PARIETAL TEMPORAL LIMBIC FRONTAL OCCIPITAL FRONTAL OCCIPITAL Comment: The cerebral lobes are arbitrary divisions of the cerebrum, taking their names, for the most part, from overlying bones. They are not functional subdivisions of the brain, but serve as a reference for locating specific functions within them. The anterior (rostral) end of the frontal lobe is referred to as the frontal pole. Similarly, the anterior end of the temporal lobe is the temporal pole, and the posterior end of the occipital lobe the occipital pole. TOPOGRAPHY T2 central sulcus central sulcus parietal frontal occipital lateral temporal lateral sulcus sulcus SUMMARY CARTOON: LOBES SUMMARY CARTOON: GYRI Lateral View of Left Hemisphere central sulcus postcentral superior parietal superior precentral gyrus gyrus lobule frontal intraparietal sulcus gyrus inferior parietal lobule: supramarginal and angular gyri middle frontal parieto-occipital sulcus gyrus incision for close-up below OP T preoccipital O notch inferior frontal cerebellum gyrus: O-orbital lateral T-triangular sulcus superior, middle and inferior temporal gyri OP-opercular Lateral View of Insula central sulcus cut surface corresponding to incision in above figure insula superior temporal gyrus Comment: Insula (insular gyri) exposed by removal of overlying opercula (“lids” of frontal and parietal cortex). TOPOGRAPHY T3 Language sites and arcuate fasciculus. MRI reconstruction from a volunteer. central sulcus supramarginal site (posterior Wernicke’s) Language sites (squares) approximated from electrical stimulation sites in patients undergoing operations for epilepsy or tumor removal (Ojeman and Berger). -
Circuits That Link the Cerebral Cortex to the Adrenal Medulla COLLOQUIUM PAPER
The mind–body problem: Circuits that link the cerebral cortex to the adrenal medulla COLLOQUIUM PAPER Richard P. Duma,b, David J. Levinthala,b,c, and Peter L. Stricka,b,1 aUniversity of Pittsburgh Brain Institute, Systems Neuroscience Center, Center for the Neural Basis of Cognition, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261; bDepartment of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261; and cDivision of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261 Edited by Robert H. Wurtz, National Institutes of Health, Bethesda, MD, and approved October 4, 2019 (received for review July 31, 2019) Which regions of the cerebral cortex are the origin of descending shortcoming has been overcome by the introduction of neuro- commands that influence internal organs? We used transneuronal tropic viruses as transneuronal tracers (4–6). transport of rabies virus in monkeys and rats to identify regions of Here,wereviewsomeofourresultsusingtheN2cstrainofrabies cerebral cortex that have multisynaptic connections with a major virus (RV) to reveal the areas of the cerebral cortex that influence sympathetic effector, the adrenal medulla. In rats, we also examined the adrenal medulla of the monkey and rat. We will also review the multisynaptic connections with the kidney. In monkeys, the cortical results of RV transport from the kidney in the rat. The adrenal influence over the adrenal medulla originates from 3 distinct networks medulla and kidney are controlled exclusively by sympathetic ef- that are involved in movement, cognition, and affect. Each of these ferents and are therefore, ideal for defining the cortical areas that networks has a human equivalent. -
Microsurgical and Tractographic Anatomical Study of Insular and Transsylvian Transinsular Approach
Neurol Sci (2011) 32:865–874 DOI 10.1007/s10072-011-0721-2 ORIGINAL ARTICLE Microsurgical and tractographic anatomical study of insular and transsylvian transinsular approach Feng Wang • Tao Sun • XinGang Li • HeChun Xia • ZongZheng Li Received: 29 September 2008 / Accepted: 16 July 2011 / Published online: 24 August 2011 Ó The Author(s) 2011. This article is published with open access at Springerlink.com Abstract This study is to define the operative anatomy of Introduction the insula with emphasis on the transsylvian transinsular approach. The anatomy was studied in 15 brain specimens, In humans, the insula is a highly developed structure, among five were dissected by use of fiber dissection totally encased within the brain. In many clinical and technique; diffusion tensor imaging of 10 healthy volun- experimental studies, a variety of functions have been teers was obtained with a 1.5-T MR system. The temporal attributed to the insula, however, the full and comprehen- stem consists mainly of the uncinate fasciculus, inferior sive role that it plays continues to remain obscure. Oper- occipitofrontal fasciculus, Meyer’s loop of the optic radi- ation of neurosurgery, specifically of epilepsy surgery, is a ation and anterior commissure. The transinsular approach window onto function and dysfunction of the human brain requires an incision of the inferior limiting sulcus. In this [1]. The insula, as part of the paralimbic system, has both procedure, the fibers of the temporal stem can be inter- invasive anatomical and functional connections with the rupted to various degrees. The fiber dissection technique is temporal lobe through white matter fibers [2–6].