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Rabbit Anti-KLRC4/FITC Conjugated antibody

SL16782R-FITC

Product Name: Anti-KLRC4/FITC Chinese Name: FITC标记的杀伤细胞凝集素样受体C亚家族成员4抗体 killer cell lectin-like receptor subfamily C, member 4; KLRC4; NK cell receptor F; Alias: NKG2 F; NKG2-F type II integral membrane ; NKG2-F-activating NK receptor; NKG2F; NKG2F_HUMAN. Organism Species: Rabbit Clonality: Polyclonal React Species: Human, ICC=1:50-200IF=1:50-200 Applications: not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. Molecular weight: 18kDa Form: Lyophilized or Liquid Concentration: 1mg/ml immunogen: KLH conjugated synthetic peptide derived from human KLRC4 Lsotype: IgG Purification: affinity purified by Protein A Storage Buffer: 0.01Mwww.sunlongbiotech.com TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year Storage: when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. background: Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium- Product Detail: dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. This is a member of the NKG2 group of that are expressed primarily in natural killer (NK) cells. These family members encode transmembrane that are characterized by a type II membrane orientation (have an extracellular C-terminus) and the presence of a C-type lectin domain. This family member is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells. Read-through transcription exists between this gene and the downstream KLRK1 (killer cell lectin-like receptor subfamily K, member 1) family member. [provided by RefSeq, Dec 2010]

Function: May play a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells.

Subunit: Can form disulfide-bonded heterodimer with CD94.

Subcellular Location: Membrane.

Tissue Specificity: Natural killer cells.

Database links:

Entrez Gene: 8302 Human

Omim: 602893 Human

SwissProt: O43908 Human

Unigene: 721094 Human

Important Note: This product as supplied is intended for research use only, not for use in human, therapeuticwww.sunlongbiotech.com or diagnostic applications.