Product datasheet [email protected]

ARG57939 Package: 100 μl anti-ACTR3B antibody Store at: -20°C

Summary

Product Description Rabbit Polyclonal antibody recognizes ACTR3B

Tested Reactivity Ms

Tested Application WB

Host Rabbit

Clonality Polyclonal

Isotype IgG

Target Name ACTR3B

Antigen Species Human

Immunogen Synthetic peptide of Human ACTR3B.

Conjugation Un-conjugated

Alternate Names ARP3-beta; -related ARP4; Actin-related protein 3B; ARP3BETA; Actin-like protein 3B; ARP11

Application Instructions

Application table Application Dilution

WB 1:500 - 1:1000

Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Positive Control Mouse bladder

Calculated Mw 48 kDa

Observed Size ~ 50 kDa

Properties

Form Liquid

Purification Affinity purified.

Buffer PBS (pH 7.3) and 0.02% Sodium azide.

Preservative 0.02% Sodium azide

Storage instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.

Note For laboratory research only, not for drug, diagnostic or other use.

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Gene Symbol ACTR3B

Gene Full Name ARP3 actin-related protein 3 homolog B (yeast)

Background This gene encodes a member of the actin-related (ARP), which form multiprotein complexes and share 35-55% amino acid identity with conventional actin. The protein encoded by this gene may have a regulatory role in the actin cytoskeleton and induce cell-shape change and motility. Pseudogenes of this gene are located on 2, 4, 10, 16, 22 and Y. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jul 2012]

Function Plays a role in the organization of the actin cytoskeleton. May function as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. May decrease the metastatic potential of tumors. [UniProt]

Cellular Localization Cell projection, Cytoplasm, cytoskeleton. [UniProt]

Images

ARG57939 anti-ACTR3B antibody WB image

Western blot: 25 µg of Mouse bladder lysate stained with ARG57939 anti-ACTR3B antibody.

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