Anti-ACTR3B Antibody (ARG57950)

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Product datasheet [email protected] ARG57950 Package: 100 μl anti-ACTR3B antibody Store at: -20°C Summary Product Description Rabbit Polyclonal antibody recognizes ACTR3B Tested Reactivity Hu Tested Application WB Host Rabbit Clonality Polyclonal Isotype IgG Target Name ACTR3B Antigen Species Human Immunogen Recombinant fusion protein corresponding to aa. 189-418 of Human ACTR3B (NP_065178.1). Conjugation Un-conjugated Alternate Names ARP3-beta; Actin-related protein ARP4; Actin-related protein 3B; ARP3BETA; Actin-like protein 3B; ARP11 Application Instructions Application table Application Dilution WB 1:500 - 1:2000 Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. Positive Control HeLa Calculated Mw 48 kDa Observed Size 47 kDa Properties Form Liquid Purification Affinity purified. Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. Preservative 0.02% Sodium azide Stabilizer 50% Glycerol Storage instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. Note For laboratory research only, not for drug, diagnostic or other use. www.arigobio.com 1/2 Bioinformation Gene Symbol ACTR3B Gene Full Name ARP3 actin-related protein 3 homolog B (yeast) Background This gene encodes a member of the actin-related proteins (ARP), which form multiprotein complexes and share 35-55% amino acid identity with conventional actin. The protein encoded by this gene may have a regulatory role in the actin cytoskeleton and induce cell-shape change and motility. Pseudogenes of this gene are located on chromosomes 2, 4, 10, 16, 22 and Y. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jul 2012] Function Plays a role in the organization of the actin cytoskeleton. May function as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. May decrease the metastatic potential of tumors. [UniProt] Cellular Localization Cell projection, Cytoplasm, cytoskeleton. [UniProt] Images ARG57950 anti-ACTR3B antibody WB image Western blot: 25 µg of HeLa cell lysate stained with ARG57950 anti- ACTR3B antibody at 1:1000 dilution. www.arigobio.com 2/2 Powered by TCPDF (www.tcpdf.org).

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