Test Items for Licensing Examination Krok 2 PHARMACY

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MINISTRY OF PUBLIC HEALTH OF UKRAINE

Department of human resources policy, education and science

Testing Board

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Test items for licensing examination

Krok 2 PHARMACY

(російськомовний варіант)

General Instruction

Every one of these numbered questions or unfinished statements in this chapter corresponds to answers or statements endings. Choose the

answer (finished statements) that fits best and fill in the circle with the corresponding Latin letter on the answer sheet.

Authors of items: Andrieiev V.H., Arkhypova N.V., Baihush Yu.V., Bevz N.Yu., Belehay R.I., Beley N.M., Benzel L.V., Bieliaieva O.I., Bilous S.B., Bohdan N.S., Bokshan Ye.V., Bratenko M.K., Bushuieva I.V, Cherkovska L.H., Chornous V.O., Darmohray R.Ye., Dasiuk Ye.V., Denys A.I., Dorokhova L.P., Doroshkevych I.O., Dovzhuk V.V., Drachuk V.M., Dzviniatska O.F., Fizor N.S., Hadiak I.V., Haina Zh.M., Harna N.V., Hasiuk H.D., Herush O.V., Hladyshev V.V., Hlushachenko O.O., Hnidets V.I., Holod A.S., Holopykho L.I., Holovkin V.O., Horbata N.Yu., Horobynska S.M., Horoshko O.M., Hromovyk B.P., Hrozav A.M., Ivaniulyk I.I., Khmelova M.O., Klebansky Ye.O., Kornieva L.O., Korobko D.B., Korovenkova O.M., Kovalchuk T.S., Kovalenko S.I., Kraidashenko O.V., Kraievska Ye.V., Kryvoviaz O.V., Kucherenko N.V., Leleka M.V., Leonova S.H., Levchenko I.O., Levytska O.R., Liapunova O.O., Lopatynska O.I., Maksymchuk N.M., Marchyshyn S.M., Markiv I.M., Mazulin O.V., Muzyka N.Ya., Nedorezaniuk N.S., Nemchenko A.S., Nemiatykh O.D., Ohar S.V., Ohdansky K.M., Okkert I.L., Palamar A.O., Panfilova H.L., Perederiy Ye.O., Peresekina N.M., Podpletnia O.A., Poliak O.B., Popova N.V., Popovych V.P., Romanyshyn N.M., Rykhlitska K.V., Sakhatska I.M., Sasko O.V., Shanaida M.I., Sikoryn U.B., Sincha N.I., Skrylova N.M., Skupa O.O., Soboleva V.O., Sokolova L.V., Stadniychuk R.F., Sterioni I.V., Taller O.Yu., Tereshchuk S.I., Ternynko I.I., Tkachenko O.P., Tkachenko V.H., Trofimova T.S., Tsveiuk N.P., Tykhonov O.I., Tykhonova S.O., Tymchenko A.Yu., Upyr L.V., Vashchenko K.F., Vidavska A.H., Vynnyk I.O., Yakovleva O.O., Yehorov I.A, Yeromina Z.H., Yevtushenko I.S, Zamorsky I.I., Zaruma L.Ie., Zeleniuk V.H., Zhyvora N.V., Zub L.O. and Committees of professional expertise.

Item reviewers: Burian H.O., Darmograi R.Ye., Hala L.O., Holopykho L.I., Hrytsenko B.I., Khokhlenkova N.V., Korobko D.B., Koval A.Ya., Kovalska N.P., Lenchyk L.V., Lesyk R.B., Levytska O.R., Marchyshyn S.M., Moriak Z.B., Nazarkina B.M., Nemiatykh O.D., Otrishko I.A., Pukhalska I.O., Samohalska O.Ye., Unhurian L.M., Vashchenko K.F., Voitenko L.P., Zhadko S.V.

The book includes test items for use at licensing integrated examination “Krok 2 Pharmacy” and further use in teaching.

The book has been developed for students of pharmaceutical faculties and academic staff of higher medical educational establishments.

Approved by Ministry of Public Health of Ukraine as examination and teaching publication based on expert conclusions (Orders of MPH of Ukraine of 14.08.1998 №251, of 27.12.1999 №303, of 16.10.2002 №374, of 16.04.2003 № 239, of 29.05.2003 №233).

1. A pharmacist prepares powders A. Once in a shift with a substance hard to comminute. B. Once in a week What substance should be commi- C. Once every 10 days nuted with a volatile liquid? D. Once every 5 days E. Once every 3 days A. Camphor B. Magnesium oxide 6. Schedule of sanitation actions C. Zinc sulfate in pharmacies is regulated by the D. Copper sulfate relevant regulatory acts. Cleaning E. Glucose day at a pharmacy must be scheduled for at least 1 time: 2. A pharmacist has prepared powders including extract of A. In a month belladonna in the amount of 0,015 B. In a week per dose. For ten doses he had to take C. In 3 days the following amount of dry extract: D. In 10 days E. In 5 days A. 0,3 g B. 0,15 g 7. A pharmaceutical company C. 1,5 g focuses on selling a diverse range of D. 0,03 g products covering different customer E. 0,015 g groups and regions. What kind of organizational structure is typical for 3. A pharmacy has prepared a soluti- such company? on of macromolecular substance with limited swelling capacity. What A. Divisional solution was labelled ”warm up B. Bureaucratic before use”? C. Functional D. Centralized A. Gelatin E. Decentralized B. Trypsin C. Pepsin 8. A pharmaceutical company D. Methyl cellulose produces cordiamin solution. Duri- E. Pancreatin ng the quality control its quantitative content was determined by means 4. A dispensing chemist can of refractometry. For this purpose an recommend a drug made from analytical chemist measured: seeds of Aesculus hippocastanum to be taken as a veintonic and anti- A. Index of refraction thrombotic agent to treat venous B. Viscosity congestion and veins dilatation of C. Density lower extremities. This drug is: D. Intensity of absorption E. Angle of rotation A. Aescusan B. Phytolysin 9. Specify which of the alkaloids gi- C. Flamin ven below will react positively to D. Marelin xanthines (murexide test): E. Ajmaline A. Caffeine 5. A pharmacy prepares drugs by B. Atropine sulfate individual prescriptions. How often C. Papaverine hydrochloride should the floors be mopped down in D. Quinine sulfate the prescription department? E. Ephedrine hydrochloride 10. Which of the following drugs is used for thrombolytic therapy in case Кrok 2 Pharmacy (англомовнi студенти) 2016 рiк 2 of myocardial infarction? ng ingredients are taken: 82 parts of sugar syrup, 1 part of KJ (KBr), A. Streptokinase 12 parts of liquid thyme extract and B. Heparin 5 parts of 96% ethanol. Name this C. Phenylinum drug: D. Ticlopidine E. Acetylsalicylic acid A. Pertussin B. Cholosas 11. A patient, who had a case of C. Ambroxol cardiac infarction, is recommended D. Broncholytin to take acetylsalicylic acid to: E. Licorice syrup A. Decrease thrombocyte aggregati- 16. A pharmaceutical enterprise that on has achieved high sales rates and B. Decrease body temperature customers’ recognition will reach the C. Dilate coronary vessels highest profitatthefollowingstage D. Decrease inflammation of the product life cycle: E. Lower cholesterol rate A. Maturity 12. Stinging nettle (Urtica dioi- B. Market penetration ca) leaves are mostly used as a C. Growth hemostatic in tinctures and liquid D. Decrease extracts to treat lung, intestinal, and E. Development uterine hemorrhages. What bioactive substance provides hemostatic 17. A marketing specialist of a retail effect? pharmacy analyzes price lists of wholesale firms and manufacturers. A. Vitamin K The key factor in the choice of a B. β-carotene supplier is: C. Rutin D. Reserpine A. Selection-price characteristics of E. Digitoxin production B. Production multifunctionality 13. What herbal bioactive substances C. Post-sale service quality yield a positive reaction with ferric D. Supply volume ammonium alum solution? E. Market conditions A. Tannins 18. Suspension workshop introduces B. Saponins production of new drugs. Specify C. Polysaccharides the optimal approach to suspension D. Bitters production: E. Fatty oils A. Grinding in a liquid medium 14. Cumulating drugs - Digitoxin B. Drop method and Соrdigitum - are used to treat C. Repercolation chronic cardiac insufficiency. What D. Percolation plant is used as the raw material in E. Maceration production of these drugs? 19. Aerosol workshop of a A. Digitalis purpurea pharmaceutical plant uses propellants B. Strophanthus kombe of different groups. What propellants C. Adonis vernalis belong to the group of compressed D. Convallaria majalis gases? E. Erysimum canescens 15. To prepare a syrup the followi- Кrok 2 Pharmacy (англомовнi студенти) 2016 рiк 3

A. Nitrogen, nitrous oxide, carbon A. Dissolution in the molten vehicle dioxide B. Emulsification and blending with B. Freons the vehicle C. Propane, butane, isobutane C. Trituration with small amount of D. Vinyl and methyl chloride water E. Methylene chloride, ethylene D. Suspending in the vehicle chloride E. Blending with vaseline oil 20. An analytical chemist confirms 24. Preparations from Althaea offi- the presence of calcium ions in calci- cinalis roots are used for treatment um lactate molecule by means of of upper airways conditions. During reaction with ammonium oxalate. harvesting this herbal raw material The reaction occurs in the medium the following can become an admi- of: xture: A. Acetic acid A. Lavatera thuringiaca B. Ammonia B. Plantago major C. Sodium hydroxide C. Tanacetum vulgare D. Formaldehyde D. Cichorium intybus E. Potassium chloride E. Taraxacum officinale 21. A pharmacist has used 25. A Ukrainian pharmaceutical condensation method to prepare a company established a subsidiary suspension. Select the substances company abroad. What organisati- that make up the precipitate: onal form of international business is it? A. Calcium chloride with sodium hydrocarbonate A. Direct possession B. Caffeine and sodium benzoate B. Direct export with zinc oxide C. Licensing C. Sodium bromide with camphor D. Contractual production of drugs D. Potassium bromide with sodium E. Joint venture benzoate E. Magnesium sulfate with potassium 26. What product strategy is iodide characterized by introducing to the market a product designed for the 22. A pharmacy received a largest market segments and maxi- formula for an extemporaneously mal amount of customers? compounded medication. Specify the document that is used to set the price A. Undifferentiated marketing for such medication: B. Differentiated marketing C. Concentrated marketing A. Retail price list for drugs D. Diversification B. Inventory report E. Var iat io n C. Certificate of quality D. Cash receipt voucher 27. Which of the following anti- E. Certificate of analysis hypertensive drugs has potassium- sparing action? 23. A pharmacist has made polyethylene oxide-based supposi- A. Triamterene tories with Streptocid. Specify the B. Furosemide approach to introducing the active C. Prazosin ingredient into the vehicle: D. Metoprolol E. Diltiazem 28. An essential oil is a component of Кrok 2 Pharmacy (англомовнi студенти) 2016 рiк 4 such compound drugs as: Inhalypt, A. Direct compression without addi- Corvalol, Pinosol, Corvaldin, tooth tional substances drops. What herbal raw material is B. Moulding the source of this essential oil? C. Direct compression with the addition of adjuvants A. Folia Menthae piperitae D. Wet granulation prior to B. Folia Betulae compression C. Folia Urticae E. Dry granulation prior to D. Folia Agavae compression E. Folia Absinthii 33. Various types of dryers can be 29. A pharmacist has been on a busi- used for granule dehumidification. ness trip. What is the deadline for Specify the type of ”СП-30” dryer: submitting a travel expense report? A. Fluidized bed dryer A. Three working days after returning B. Freeze dryer from a trip C. Infrared dryer B. Four working days after returning D. Silica gel dryer from a trip E. Forced air dryer C. Ten working days after returning from a trip 34. Ampoule workshop of a factory D. A week after returning from a trip produces injection solution. Name E. There is no deadline the stabilizer to be added to 1% morphine hydrochloride injection 30. A pharmacy prepares atropine solution: sulfate trituration. What adjuvant should be used to prepare this tri- A. 0,1 N solution of hydrochloric acid turation? B. 0,1 N solution of sodium chloride C. Amino-propylene-glycol A. Lactose D. Rongalite B. Saccharose E. Sodium metabisulfite C. Glucose D. Starch 35. An analyst of a chemical E. Ta l c u m laboratory obtained a glucose substance for analysis. To check its 31. To prepare a suspension a medi- quality he used a polarimeter. The cinal substance should be triturated analyst measured: with a small amount of liquid. Specify the optimal amount of liquid for tri- A. Angle of rotation turation of 10 g of zinc oxide accordi- B. Refractive index ng to the Deryagin’s rule: C. Optical density D. Melting point A. 5ml E. Specificgravity B. 10 ml C. 2ml 36. Rhamnus cathartica herbal raw D. 1ml material can be used as a laxative. E. 0,5 ml What plant parts are harvested for drug producton? 32. A pharmaceutical factory produces tablets of sodium chloride. A. Fruit What is the method of their producti- B. Leaves on? C. Bark D. Roots E. Sprouts 37. Crude drugs CANNOT be tasted Кrok 2 Pharmacy (англомовнi студенти) 2016 рiк 5 if they contain: A. 10 days B. 3 months A. To x i n s C. 1 year B. Essential oils D. 15 days C. Polysaccharides E. 20 days D. Bitter glycosides E. Vitamins 42. Companies producing injectable dosage forms apply different 38. During microscopy of Althaea methods of ampoule sealing. Sealing root it is necessary to determine the against a jet of inert gases (nitrogen, presence of starch granules within argon, carbon dioxide) is suitable for the plant cells. What reagent enables the following injection solutions: such analysis? A. Easily oxidable A. Lugol’s solution B. Viscous B. Ammonium hydroxide C. Thermostable C. Concentrated sulfuric acid D. Hydrolytically unstable D. Alcohol solution of α-naphthol E. Photosensitive E. Thymol solution 43. An analytical chemist of a central 39. Collective labour agreement is industrial laboratory performs concluded by a trade union commi- quantitative determination of peni- ttee with the enterprise owner on cillin sum in benzylpenicillin sodium behalf of the workforce. Any collecti- salt by means of iodometric method. ve agreement is worked out in wri- What indicator is used? tten form. Which article of the Labor Code regulates the duration of the A. Starch collective agreement? B. Phenolphthalein C. Potassium chromate A. 17 D. Methyl orange B. 36 E. Methyl red C. 38 D. 40 44. A pharmacist prepares cocoa E. 41 butter-based round vaginal suppositories with less than 5% of citric acid. 40. For the purpose of sales sti- Specify the most rational approach to mulation a pharmaceutical wholesale introduction of the active ingredient company grants its customers a into the vehicle: discount according to the social contract and on condition of their A. Dissolve in minmal quantity of loyalty. Specify the type of discount: purified water B. Dissolve in Dimexid (Di- Bonus A. methylsulfoxide) B. Dealer Seasonal C. Dissolve in molten cocoa butter C. Dissolve in vaseline oil D. Discounts for quantity of D. purchased goods E. Dissolve in alcohol E. - 45. Suppositories are prepared by 41. Before goods are accepted by a various methods such as rolling, pharmacy, they should be checked pouring, pressing. What base is used for quantity and quality. If there is in the pouring method? no discrepancy, the pharmacy issues a warrant for receipt of goods. This warrant is valid for: Кrok 2 Pharmacy (англомовнi студенти) 2016 рiк 6

A. Butyrolum thermolabile compounds? B. Paraffin C. Cocoa butter A. Freeze dryer D. Vaseline B. Roller dryer E. Coriander oil C. Band dryer D. Drying oven 46. A pharmacist has made an injecti- E. Drum dryer on solution with 0,1 M of sodium hydroxide solution as a stabilizer. 51. An analytical laboratory has What substance requires such stabili- received a procaine hydrochloride zer? substance for analysis. According to the State Pharmacopoeia of Ukraine A. Caffeine and sodium benzoate limit content of heavy metals should B. Dibazol (Bendazol) be determined with the following C. Sodium hydrocarbonate reagent: D. Sodium chloride E. Glucose A. Thioacetamide B. Methoxyphenylacetic acid 47. Anesthesin is a substance with C. Hypophosphite local anesthetic activity and a deri- D. Aminomethyl alizarin acetic acid vative of the following acid: E. Sulfomolybdenum A. Para-aminobenzoic 52. Select a reagent that should be B. Para-aminosalicylic applied by an analytical chemist to C. Para-aminobenzolsulfonic detect alkaloids in the herbal raw D. Para-chlorbenzoic material: E. Para-aminophthalic A. Dragendorff reagent 48. Paracetamol substance has been B. Bromine water received for analysis. Reaction wi- C. Alkaline solution th the solution of iron (III) chlori- D. Stahl’s reagent de resulted in blue-purple color. This E. Trim-Hill reagent indicates the presence of: 53. A warehouse received a batch A. Phenolic hydroxyl of herbal raw material consisting B. Aldehyde group of peppermint leaves. Specify the C. Keto group storage conditions for this herbal D. Ester group material: E. Alcoholic hydroxyl A. Separately from other herbal raw 49. Production of tablets requires materials stage-to-stage quality control. What B. Under the regular conditions devices are used to determine the C. In metal storage containers particle size distribution (fraction) of D. Protected against CO2 granules? E. At the temperature of -5oC A. Standard set of sieves 54. For a month a pharmacy has B. Various vibrosieves been receiving multiple deliveries C. Blade friabilators from various suppliers. What accrual D. Laboratory identifiers document is used to record the goods E. Microscope received by the pharmacy? 50. Various dryer types are used in production of herbal and animal- derived drugs. What dryer would be optimal for dehumidification of Кrok 2 Pharmacy (англомовнi студенти) 2016 рiк 7

A. Merchandise activity report A. Samples of director’s and chief B. Invoice register accountant’s signatures C. Receipt log book B. Record card D. Cash book C. Payment document for registration E. Debit/credit invoice fee D. Payment document confirming 55. A set of values, traditions, behavi- owner’s assessed contribution oral norms and views inherent to an E. Constituent documents organisation characterize its following feature: 59. For better coverage of various markets the Lubnyfarm company A. Culture sells a portion of its production B. Success through its chain of pharmacies, C. Profitability another portion is being sold through D. Capitalization level distributors, and the third - through E. Self-development capability pharmacies of another owners. What marketing system of distribution is 56. Products differentiation (advantages) used by this company? pursued by a pharmaceutical company with the aim to surpass its A. Multichannel competitors in satisfying customers’s B. Horizontal demands is called: C. Corporate D. Contractual A. Product leadership E. Administered B. Benchmarking C. Porter’s generic strategies model 60. One of the most important D. Penetration strategy market characteristics is a goods E. Concentration strategy economic trend. What economic trend can be characterized by relati- 57. Sterilization methods used for the ve stability of high prices and the hi- preparation of drugs under aseptic ghest activity of manufacturers and conditions can be differentiated into customers? physical, mechanical, and chemical ones. Specify the chemical method of A. High (stable) sterilization: B. Subsiding C. Downward A. Addition of preservatives D. Sluggish B. Dry heat sterilization E. Low C. Radiation sterilization D. Pressure steam sterilization 61. A patient has been administered E. UV light sterilization powders containing menthol. What is the best way to achieve the required 58. One of the first stages of busi- extent of menthol comminution? ness activity is to register an enterprise with public authorities. What A. To triturate it with alcohol or ether documents NEED NOT be submi- B. To triturate it with glycerine or tted to the local authorities for state chloroform registration of an enterprise? C. To triturate it with purified water D. To triturate it with other components of the formula E. To triturate it thoroughly with sugar 62. An analytical laboratory received a sample of alpha-aminobutyric acid for analysis. What reagent should Кrok 2 Pharmacy (англомовнi студенти) 2016 рiк 8 be used by the analytical chemist to A. Paddle, flow-through cell identify this substance? B. Rotating basket, flow-through cell C. Paddle, rotating basket A. Ninhydrin D. Flow-through cell B. Sodium nitrate E. Rotating basket C. Benzene D. Aniline 67. When doing calculations to E. Calcium bromide determine the limit of the cash balance, an accountant must speci- 63. A retail pharmacy has been fy the actual amount of cash receipts. purchasing goods within an accounti- What time period should be taken ng period. What changes to the into account? balance will result from this business transactions? A. Three months prior to calculation B. Six months prior to calculation A. Increase in assets and liabilities C. 1 year prior to calculation B. Decrease in assets and liabilities D. 10 days prior to calculation C. Changes will affect only the assets E. 7 days prior to calculation D. Changes will affect only the liabilities 68. A certain plant is used for E. - production of tinctures and extracts that are a part of complex drugs, such 64. Which of the following non- as Bellataminal, Becarbon, Besalol, steroid anti-inflammatory agents etc. Specify the grass that is used for has the least harmful effect on the this purpose: mucosa of gastrointestinal tract? A. Belladonna A. Nimesulide B. Lily of the valley B. Diclofenac C. Astragalus C. Indomethacin D. Beggarticks D. Piroxicam E. Celandine E. Acetylsalicylic acid 69. A pharmacist has prepared a drug 65. When preparing an ointment wi- by the following prescription: th castor oil and vaseline a pharmaci- Rp.: Streptocidi st failed to obtain a homogeneous Dermatoli ana 1,0 system. What is the most likely cause Lanolini of incompatibility between these Vaselini ana 5,0 components? M.D.S.: Apply to the affected area of skin. Specify the type of the disperse A. Immiscibility of the ingredients system: B. Limited solubility C. Release of crystallization water A. Suspension ointment D. Coagulation B. Solution ointment E. Adsorption C. Hydrophilic ointment D. Combined ointment 66. Tablet quality is assessed E. Extraction ointment through various indicators. Name the apparatuses used to measure tablet 70. Which of the following antibiotics dissolution: can be identified by means of maltol test? Кrok 2 Pharmacy (англомовнi студенти) 2016 рiк 9

A. Streptomycin sulfate A. Medicaments B. Doxycycline hydrochloride B. Baby food C. Amoxicillin C. Optics D. Lincomycin hydrochloride D. Curative cosmetics E. Kanamycin monosulfate E. Perfumes 71. What concept can be described 75. During processing, drying and as determining the goods specificati- refinement of herbal raw materials ons, special features that distinguish containing saponins the dust parti- these goods from their competitor- cles can cause mucosa irritation. manufactured analogues? Therefore, precautionary measures should be observed when working A. Positioning with: B. Selection C. Quality A. Rhizoma et radices Polemonii D. Demand B. Rhizomata Tormentillae E. Consumer value C. Radices Araliae D. Rhizomata Bistortae 72. Aerosols contain active ingredi- E. Rhizomata et radices Rubiae ents, solvents, propellants. What substances can be used as 76. An analytical chemist identifies propellants? the substance of potassium acetate. What reagent confirms the presence A. Freon 11, carbon monoxide, of potassium cation in the substance? propane/butane mixture B. Isopropyl myristate, neon, sulfur A. Tartaric acid oxide B. Sodium hydroxide C. Glycerine, argon, helium C. Potassium permanganate D. Linaetholum, myristinic acid, D. Iron (III) chloride benzocaine E. Zinc oxide E. Hydrogen sulfide, hydrogen, tri- ethanolamine 77. A pharmacy has received a batch of drugs from a pharmacy depot. 73. White precipitate produced Specify the drug subject to the by the reaction of morphine controlled substance inventory in hydrochloride with ammonia soluti- pharmacies: on dissolves in sodium hydroxide solution due to the presence of the A. Dicaine following group in the structure of B. Paracetamol morphine hydrochloride: C. Analgin D. Novocaine A. Phenolic hydroxyl E. Acetylsalicylic acid B. Carboxyl group C. Aldehyde group 78. A pharmaceutical company D. Alcoholic hydroxyl conducted an age-specific segment E. Keto group analysis of the regional antihistamine market. It revealed the lack of antihi- 74. A pharmacy plans to purchase stamines for children. The company and retail goods of different stock will consider this segment as: record units. Which group of goods does VAT reduction apply to? Кrok 2 Pharmacy (англомовнi студенти) 2016 рiк 10

A. Amarketniche 83. Quality of viscous extracts is B. An unattractive segment assessed based on a variety of indi- C. Amarketshare ces. Specify the maximum allowed D. A segment requiring further moisture content of viscous extracts research according to the regulations of the E. A market door State Pharmacopoeia of Ukraine: 79. The manufacturing pharmaceuti- A. 30% cal company ”Elema” has set up B. 20% its own corporate pharmacy. In this C. 10% case, it uses the following distributi- D. 5% on channel: E. 100% A. Zero level 84. Injection solutions in ampoules B. First level are assessed through various indi- C. Second level cators. What percentage of ampoules D. Third level should be checked for mechanical E. Fourth level impurities? 80. What type of market can be A. 100% characterized by the following condi- B. 98% tions: there are many sellers and C. 95% buyers, who have no influence D. 90% over current prices; similar and E. 50% interchangeable competing goods are available; no price limits? 85. A pharmacy prepares suspensi- ons. What substance can be used for A. Pure competition preparing a suspension without addi- B. Monopolistic competition ng a stabilizer? C. Oligopoly D. Pure monopoly A. Magnesium oxide E. Economic planning B. Camphor C. Sulfur 81. An analytical laboratory recei- D. Menthol ved the task to confirm the presence E. Phenyl salycylate of ethylenediamine in aminophylli- ne. Which of the following reagents 86. During planned inventory of cash allows to detect ethylenediamine? money in a pharmacy cash register there is an unaccounted surplus di- A. Copper (II) sulfate scovered. What should a committee B. Sodium hydroxide do with this surplus? C. Concentrated sulfuric acid D. Silver nitrate A. Record as received E. Barium chloride B. Transfer to authorized capital C. Transfer to accounts payable 82. Specify the indicator that D. Transfer to accounts receivable measures the total contribution E. Transfer to emergency fund of various solutes to the osmotic pressure of the solution: 87. To c o n firm the presence of sulfat ions in the medicinal preparation A. Osmolality of magnesium sulfate an analyti- B. Isohydricity cal chemist of a pharmacy uses the C. Isotonicity following solutions: D. Isoviscosity E. Apyrogenicity Кrok 2 Pharmacy (англомовнi студенти) 2016 рiк 11

A. Barium chloride and hydrochloric 92. A pharmacist working at an acid analytical laboratory is performing B. Ammonium chloride and ammoni- sulfite-ion identification of a drug in um hydrate compliance with the requirements C. Silver nitrate and nitric acid of State Pharmacopoeia of Ukraine. D. Benzenesulfonic acid What reagent becomes colorless in E. Diphenylamine this investigation? 88. Streptocide, sulfacyl sodium, A. Iodine solution norsulfazole or sulfadimezinum can B. Iron (III) chloride solution be identified by means of the reacti- C. Ammonia solution on that forms: D. Potassium iodide solution E. Potassium nitrate solution A. Azo dye B. Murexide 93. An analytic laboratory received C. Iodoform ”Aether anaestheticus” for analysis. D. Fluorescein Which reagent should be used for E. - detection of acetone and aldehyde admixtures according to the State 89. Pharmaceutical market is in such Pharmacopoeia of Ukraine? a situation when there is only one company selling a certain product. A. Alkaline solution of potassium Specify the competitive structure of tetraiodomercurate the market: B. Ammonium solution of argentum nitrate A. Pure monopoly market C. Aqueous solution of potassium B. Pure competition market iodide C. Monopolistic competitive market D. Sodium hydrosulphite D. Oligopolistic market E. Hydroxylamine solution E. Pure monopoly market and oligopolistic market 94. Natural persons registered as small business entities with simpli- 90. A pharmaceutical company has fied taxation scheme (2 group) are made a decision to expand its activiti- subject to the limit of the annual es. The process of the company’s acti- amount of sales proceeds. Specify the vity expansion by penetration into proceeds limit: new fields of the branch is called: A. 1 million UAH A. Diversification B. 750 thousand UAH B. Segmentation C. 100 thousand UAH C. Conglomeration D. 3 million UAH D. Integration E. 5 million UAH E. Centralization 95. Fatty oil containing unsaturated 91. An analytical chemist determines fatty acids is used for the prevention the quantity of a drug by the method of atherosclerosis. Specify the herbal of indirect bromatometry. Which of raw material used in oil production: the following titrated solutions is to be used? A. Seeds of flax B. Seeds of fennelflower A. Sodium thiosulfate C. Fruits of dill B. Calcium bromate D. Fruits of black chokeberry C. Sodium edetate E. Hawthorn berries D. Sodium nitrite E. Silver nitrate 96. Quality of dried extracts is assessed according to several cri- Кrok 2 Pharmacy (англомовнi студенти) 2016 рiк 12 teria. Specify the highest acceptable neurasthenia, insomnia, menopausal amount of moisture in dried disorders? extracts according to the State Pharmacopoeia of Ukraine: A. Novopassit B. Ergotamine A. 5% C. Glaucine hydrochloride B. 25% D. Securinine nitrate C. 20% E. Vinblastine D. 75% E. 95% 102. A pharmacist prepares 3000 ml of valerian root infusion for a hospi- 97. When preparing dermatological tal department. The given amount of ointments the following substance extract should be infused in a water should be introduced by suspending: bath for: A. Xeroform A. 25 minutes B. Camphor B. 45 minutes C. Menthol C. 15 minutes D. Protargol (silver proteinate) D. 10 minutes E. Ephedrine hydrochloride E. 30 minutes 98. Benzathine benzylpenicillin is the 103. A pharmacist has prepared a drug of choice for treatment of the solution of menthol oil. Specify the following disease: dissolution temperature of the active substance: A. Syphilis B. Intestinal infection A. 40-50oC C. Pneumonia B. 60-70oC D. Tonsillitis C. 30-40oC E. Furunculosis D. 70-80oC E. 20-30oC 99. The main active substances of senna leaves and fruits are sennosi- 104. The risk can arise from some des A, B, C, D. They belong to the forms of activity connected wi- following class of biologically active th production of goods and servi- substances: ces, their selling, commodity-money and financial operations, commerce, A. Anthracene derivatives implementation of socioeconomic B. Phenolic acids and scientific-and-technical projects. C. Flavonoids This is the definition of the following D. Iridoids concept: E. Thioglycosides A. Business risk 100. Codeine is used as a cough- B. Loss of property depressant. What herbal raw materi- C. Labour loss al contains this alkaloid? D. Loss of time E. Financial loss A. Pods of opium poppy B. Pods of plume poppy 105. Althaea roots are used as a C. Celandine grass mucolytic agent. Underground parts D. Grass of common periwinkle of this plant are harvested: E. Tea leaves 101. What herbal drug produced form alkaloid-containing raw materials can be recommended for Кrok 2 Pharmacy (англомовнi студенти) 2016 рiк 13

A. After the seeds have ripened, and A. Triple heating of solution to 40- the above-ground part have died off 60oC with 24-hour-long intervals in B. In the period of blossoming between for thermostating C. In the period of fruiting B. Autoclaving at 119-121oC with D. In the period of budding pressure at 1,0-1,1 atm E. In the period of stem extension C. Sterilization with ﬂowing steam at 100oC 106. Substance of calcium pangamate D. Sterilization with dry heat at 180- is to be studied in an analytical 200oC for a lengthy period of time laboratory. Calcium cations form E. Sterilization with high-frequency white precipitate with the following and microwave frequency current reagent: 110. What ﬁnal document is used for A. Ammonium oxalate the preparation of the report on the B. Sodium chloride discrepancies revealed in the course C. Potassium permanganate of the inventory at a pharmacy? D. Potassium bromide E. Sodium cobaltinitrite A. Act on the inventory results B. Inventory item description 107. In cases of inorganic mercury C. Checklist compounds poisoning the following D. Commercial report drug should be used for antidotal E. Invoice therapy: 111. According to the basic regulati- A. Unithiol (Dimercaptopropane ons for supply of medical products, sulfonate) pharmacies should be supplied with B. Naloxone medicaments that have a remaining C. Calcium tetacine shelf life of no less than ...%, and D. Desferal (Deferoxamine) bacterial preparations of no less than E. Dexamethasone ...%: 108. As a pharmacist was serving a A. 60%, 40% customer, who ordered a nonprecri- B. 80%, 60% ption drug, he realized that the pati- C. 50%, 40% ent did not apprehend the verbal D. 40%, 20% information. Name the communicati- E. 60%, 30% ve barriers that arise when words or symbols may have different meani- 112. A pharmaceutical enterprise ngs for the information sender and produces ointments. What base is the receiver: used for production of sulfur ointment simple? A. Semantic barriers B. Neglect of facts A. Emulsion C. Nonverbal barriers B. Vaseline D. Failure to understand the C. Base ”For ophthalmic ointments” importance of information D. Lanolin E. Stereotypes of thinking E. Polyethylene glycol 109. Tyndallization is used at a 113. Powders that quickly enter into pharmaceutical factory as one of a reaction in presence of water and sterilization methods for thermolabi- emit carbon dioxide belong to the le substances. What is the essence of following group: this method? Кrok 2 Pharmacy (англомовнi студенти) 2016 рiк 14

A. Effervescent powder severe pneumonia has been admi- B. Soluble powder nistered ceftriaxone 1 time per day. C. Powders for oral use The drug should be taken once a day D. Nasal powders due to its following property: E. Powders for external use A. Slow excretion 114. While filling hard gelatin B. Presence of bactericidal action capsules such glidants as 0,1% - 0,3% C. Wide range of action aerosil or magnesium stearate along D. Cumulative ability with 0,5% - 1% talcum are often E. Poor absorption from the injection added to the filling agent in order to site improve the following properties: 119. A pharmacist is preparing an oi- A. Flowability ntment under aseptic conditions on B. Homogeneity the sterile ointment base - composi- C. Regulation of moisture content tion of vaseline and lanoline at a D. Homogeneity of mixing ratio 6:4. The drug substance is E. Ability to contact molding incorporated by suspending. Such technology of ointment preparation 115. A patient suffering from is typical for the following substance: bronchial asthma has been diagnosed with essential hypertension. What A. Benzylpenicillin sodium salt antihypertensive drug is contraindi- B. Sodium chloride cated in this case? C. Thiamine chloride D. Pilocarpine hydrochloride A. Propranolol E. Sodium sulfate B. Captopril C. Amlodipine 120. Mixers are used to obtain D. Hypothiazid (Hydrochlorothiazi- a homogeneous mixture of free- de) flowing materials. What mixers have E. Verap am il no rotating details? 116. A female patient in the first tri- A. Fluidized bed mixers mester of her pregnancy has been di- B. Drum mixers agnosed with acute pyelonephritis. C. Blade mixers What is the antibiotic drug of choice D. Double cone blenders for treatment of this patient? E. Centrifugal mixers A. Amoxicillin 121. In the course of isoniazid identi- B. Norfloxacin fication a pharmacy analyst has C. Gentamicin thoroughly boiled the substance wi- D. Chloramphenicol th 2,4-dinitrochlorobenzene. The E. Amikacin substance colored yellow, after addi- ng alkaline solution it colored first 117. Which group of adjuvants violet and then brownish-red. As the includes polyvinyl alcohol allowed result of this reaction the following for use under the State Pharmacopoeia aldehyde derivative is produced: of Ukraine regulations? A. Glutaconic A. Prolongators B. Gluconic B. Preservatives C. Glutamic C. pH adjusters D. Glyoxylic D. Antioxidants E. Hexanic E. Isotonizing agents 122. A routine inventory revealed a 118. A patient with moderately cash shortage. Who has to reimburse Кrok 2 Pharmacy (англомовнi студенти) 2016 рiк 15 the sum of the revealed shortage? A. 1,0 g of anhydrous lanolin and 9,0 g of vaseline A. Cashier B. 1,0 g of anhydrous lanolin and 29,0 B. Pharmacy director g of vaseline C. Deputy director of a pharmacy C. 12,0 g of anhydrous lanolin and D. Department head 18,0gofvaseline E. Deputy head of a department D. 27,0 g of anhydrous lanolin and 3,0 g of vaseline 123. A 43-year-old patient with a E. 10,0 g of anhydrous lanolin and severe form of rheumatoid arthritis 20,0 g of vaseline has been administered a certain drug for background therapy. Specify this 127. Rifampicin is a cytochrome P drug: 450 inducer; therefore, its interaction with other chemically active drugs: A. Methotrexate B. Diclofenac sodium A. Can decrease concentration of C. Nimesulide other drugs D. Prednisolone B. Can increase concentration of E. Methylprednisolone other drugs C. Has no effect on concentration of 124. A process dealing with drawi- other drugs ng the documents, their processi- D. Can result in binding with other ng, circulation and storage is metabolites called records management. If all E. Has no effect on toxicity of other documents circulate through one drugs organisation center, - office desk, - then such system of records 128. Bronchodilatory effect of a management is called: short-acting β2-adrenoceptor agoni- st, - salbutamol, - develops after: A. Centralized B. Decentralized A. 5-10 minutes C. Mixed B. 20-30 minutes D. Referent C. 45-60 minutes E. Specialized D. 2-3 hours E. 4-6 hours 125. A pharmacy received a formula for an alcohol solution of 129. Representatives of the family methylene blue with unspecified Solanaceae are widely used in medi- alcohol concentration. In this case, a cal practice as alkaloid-containing pharmacist should use ethyl alcohol plants. Which representative is the of the following concentration: source for production of semi- synthetic steroid hormones? A. 60% B. 90% A. Solanum laciniatum C. 70% B. Atropa belladonna D. 96% C. Datura Stramonium E. 40% D. Hyoscyamus niger E. Solanum tuberosum 126. A pharmacist needs to prepare 10,0 g of eye ointment vehicle. What 130. Grass of Equisetum arvense amounts of lanolin and vaseline is recommend as a diuretic. What should be taken? herbal raw material can be used as a substitute? Кrok 2 Pharmacy (англомовнi студенти) 2016 рiк 16

A. Herba Aervae lanatae B. Herba Leonuri A. Granules C. Herba Menthae piperitae B. Ta b l e t s D. Herba Convallariae C. Te a E. Herba Adonidis D. Spansules E. Dragee 131. Under the State Pharmacopoeia of Ukraine (appendix 2) leaves of gi- 136. What method is recommended nkgo are standardized by the content by the State Pharmacopoeia of of: Ukraine for quantitative determination of potassium chloride A. Flavonoids substance that is used in treatment B. Saponins of hypokalemia? C. Alkaloids D. Coumarins A. Argentometry E. Chromones B. Bromatometry C. Iodometry 132. During employment a pharmacy D. Cerimetry manager provides a dispensing E. Polarimetry chemist with job description. Such communication is called: 137. A 35-year-old patient with tachycardia has been administered A. Descending propranolol. Which of the following B. Ascending reactions may be caused by the use C. External of beta-blockers? D. Informal E. Non-verbal A. Bronchospasm B. Drug dependence 133. Some of the local buisnesses has C. Cumulation entered into a temporary statutory D. Blood pressure rise association to buy medical goods E. Constipations from foreign manufactures. Name such association: 138. Diazotization reaction with the following azo compound is common A. Consortium for the substances with primary ami- B. Concern no groups. What drug DOES NOT C. Corporation yield this reaction? D. Association E. Syndicate A. Barbital B. Benzocaine 134. A pharmaceutical manufacturer C. Procaine hydrochloride sets the price for a drug basing on D. Procaineamide hydrochloride its prime cost with premium. What E. Sulfanilamide model of pricing is it? 139. Cash receipts and payments A. Cost-based at a pharmacy are recorded in a B. Competitive cashbook. Which of the followi- C. Demand-based ng cash transactions IS NOT D. Supply-based REGARDED as a receipt transacti- E. Breakeven on? 135. A dosage form for internal use, which consists of round or irregular- shaped uncoated grains containing mixture of active ingredients and adjuvants, is called: Кrok 2 Pharmacy (англомовнi студенти) 2016 рiк 17

A. Issuing funds to be accounted for 144. A dispensing chemist with B. Recognizing cash receipts from calculated length of service of 7 years sales at a pharmacy has fallen ill. What percent of the C. Recognizing cash receipts from sum stated in her sick list would she sales at pharmacy stands and outlets receive? D. Return of unused disbursement funds A. 80% E. Recognizing accrued salaries and B. 100% advance payable C. 70% D. 60% 140. Phytochemical workshop of E. 50% a factory manufactures pancreatin. What is the source material for obtai- 145. Quantitative determination of ning pancreatin? sodium tetraborate according to the State Pharmacopoeia of Ukraine A. Pancreas of pigs or cattle regulations is performed by means of B. Gastric mucosa of pigs alkalimetry method in the presence C. Lungs of cattle of: D. Heart of cattle E. Egg white A. Mannitol B. Acetic anhydride 141. The following substance is used C. 96% ethanol as an extractant in production of li- D. Mercury (II) acetate quid extracts: E. Formaldehyde A. Ethanol 146. Quantitative content of a certain B. Acetone medicinal substance can be determi- C. Dichloroethane ned by means of nitritometry only if D. Chloroform hydrolisis had been performed prior E. Glycerine to it. Name this substance: 142. A patient with signs of morphi- A. Streptocide soluble ne intoxication has been delivered B. Norsulfazole into an admission room. Name the C. Benzocaine necessary antidote: D. Dicain (Tetracaine) E. Procaine hydrochloride A. Naloxone B. Collargol 147. Specialists of a pharmaceutical C. Essentiale enterprice conﬁrm the identity of D. Ectericidum Cassia acutifolia herbal raw materi- E. Trental (Pentoxifylline) al. During reaction with alkali it developed cherry-red coloring. What 143. A patient, who had been taki- substances were identiﬁed? ng acetylsalicylic acid, has developed hemorrhages of mucous membranes. A. Anthraquinones This phenomenon is associated with: B. Tannins C. Alkaloids A. Inhibition of prothrombin D. Glycosides synthesis E. Iridoids B. Increased absorption in gastrointestinal tract 148. Menthol has anesthetic and C. Decreased absorption in gastroi- antiseptic effect. What herbal raw ntestinal tract material is the source of menthol? D. Disorder of protein binding E. Changed volume of distribution Кrok 2 Pharmacy (англомовнi студенти) 2016 рiк 18

A. Folia Menthae piperitae ty of this herbal raw material is B. Folia Uvae ursi assessed by the content of: C. Folia Eucalypti D. Folia Salviae A. Essential oil and proazulenes E. Folia Absinthii B. Alkaloids C. Polysaccharides 149. The main method of quantitati- D. Cardiac glycosides ve determination of corticosteroids E. Vitamines is: 153. To analyze market activity and A. Spectrophotometry determine its place within the market B. Potentiometry a pharmaceutical company should C. Cerimetry evaluate its potential: strengths and D. Argentometry weaknesses within the company E. Acidimetry itself (internal factors), as well as opportunities and threats recei- 150. Thyme grass is used for the ved from the market environment production of herbal drugs for the (external factors). It can be done wi- treatment of respiratory tract infecti- th: ons. Under the State Pharmacopoeia of Ukraine the herbal raw materi- A. SWOT analysis al is subject to chromatographic B. Ansoff’s matrix identification by means of thin layer C. Boston Consulting Group chromatography. What substances D. Porter’s matrix are detected on the chromatographic E. ABC analysis plate after its treatment with due reagent? 154. Mercazolil (Thiamazole) is widely applied in medicine as an anti- A. Thymol and carvacrol thyroid agent. What heterocycle is its B. Atropine and hyoscyamine structure based on? C. Quercetin and rutin D. Apigenin and luteolin A. Imidazole E. Arbutin and methyl arbutin B. Triazole C. Pyrazole 151. Eucalyptus leaves contai- D. Pyrrole ns essential oil and are used in E. Imidazoline production of bactericidal herbal drugs. According to the State 155. A 48-year-old woman addressed Pharmacopoeia of Ukraine this a dispensing chemist with complaints herbal raw material can be identifi- of constipations developing after she ed with thin-layer chromatography. had started treatment of her chronic After the chromatographic plate is cardiovascular disease. What drug processed with reagent, the followi- can slow down intestinal peristalsis? ng should be identified: A. Verap am il A. Cineole B. Folic acid B. Quercetin C. Losartan C. Scopoletin D. Ascorbic acid D. Apigenin E. Enalapril E. Glaucine 156. To identify medicinal substances 152. Yarrow grass is a component containing calcium an analytical of herbal gastrointestinal remedi- chemist uses solution of: es and is used to make herbal drugs. According to the State Pharmacopoeia of Ukraine the quali- Кrok 2 Pharmacy (англомовнi студенти) 2016 рiк 19

A. Glyoxal-hydroxyanil A. Bismuth subcitrate B. Potassium thiocyanate B. Famotidine C. β-naphthol C. Omeprazole D. Hexamethylenetetramine D. Lansoprazole E. Potassium permanganate E. Ranitidine 157. Calcium gluconate is tested for 161. A 43-year-old patient was deli- presence of saccharose and reduci- vered to an admission room with ng sugars admixtures with copper- renal colic attack. What group of tartrate reagent. If these admixtures drugs would be the most efficient are present the substance colors: during the attack? A. Red A. Antispasmodics B. Blue B. Hepatoprotectors C. Green C. Antacids D. Turquoise D. Antibiotics E. White E. Cholagogues 158. A drug has just entered the 162. A bus driver addressed a market and requires considerable pharmacy due to his suffering from investments, while does not return allergic rhinitis. What antihistamine substantial profits, and is currently at with minimal sedative action can you the introduction stage. What group recommend? of products (strategic economic units) does this drug belong to according A. Loratadine to the Boston Consulting Group? B. Clemastine C. Astemizole A. Problem children D. Diphenhydramine B. Dogs E. Chloropyramine C. Stars D. Cash cows 163. What antibiotic has beta-lactam E. - cycle in its structure? 159. A 5-year-old boy suffering from A. Benzylpenicillin potassium salt pneumonia has problems with mucus B. Doxycycline hyclate expectoration. A doctor prescribed C. Chloramphenicol him a mucolytic drug that stimulates D. Streptomycin sulfate surfactant synthesis. Name this drug: E. Lincomycin hydrochloride A. Ambroxol 164. A 36-year-old patient complai- B. Carbocisteine ns of general weakness, somnolence, C. Mucaltin increased brittleness of nails, loss of D. Acetylcysteine hair. The patient was diagnosed with E. Potassium iodide iron-deficiency anemia. What drug should be prescribed for treatment? 160. A patient with peptic ulcer disease has developed black- A. Ferric sulfate colored feces during combined B. Cyanocobalamin pharmacotherapy. Name the drug C. Folic acid that can be the cause of this D. Myelosanum (Busulfan) development: E. Riboxin (Inosine) 165. What hypotensive drug is an agent of choice for the patients suffering from arterial hypertension with concomitant type I diabetes Кrok 2 Pharmacy (англомовнi студенти) 2016 рiк 20 mellitus? A. Captopril B. Diltiazem A. Lisinopril C. Hydrochlorothiazide B. Hydrochlorothiazide D. Nebivolol C. Atenolol E. Prestarium (Perindopril) D. Labetalol E. Carvedilol 170. A business entity working in drug retail trade should keep 166. To identify ouabain (a cardi- the documents confirming the fact ac glycoside) an analytical chemi- of a sale, where there are name, st performs a reaction with dini- date, amount and series of a recei- trobenzene solution in alkaline medi- ved drug stated, along with suppli- um. What molecule fragment can be er information and license details. determined by this reaction? These documents are retained for: A. Five-membered unsaturated A. 3 years lactone ring B. 1 year B. β-lactam cycle C. 2 years C. Pyridine cycle D. 6 months D. Benzene ring E. 5 years E. Purine cycle 171. A private pharmacy received a 167. A pharmacy employee has supply of a drug with 2,3-dihydro- to work during night time. What 2-methyl-1,4-naphthoquinone-2- document must be used as a basis for sulfonate sodium as an active pay rise calculation by an employer ingredient. Name this drug: in this case? A. Vicasol (Menadione) A. Collective agreement B. Rutin B. Internal memorandum C. Riboflavin C. Employee’s application D. Ergocalciferol D. Expense report E. Cocarboxylase hydrochloride E. Income summary 172. A 53-year-old woman suffers 168. A pharmacy received a batch from ischemic heart disease and angi- of drugs from a supplier. What type na pectoris. What drug can be used to of drug quality control should be stop angina pectoris attacks? performed in the pharmacy by an authorized person? A. Nitroglycerine B. Drotaverine hydrochloride A. Incoming C. Propranolol B. Chemical D. Dipiridamol C. Physical E. Acetylsalicylic acid D. Laboratory E. Complete chemical 173. A patient is 20 years old. After she was stung by a bee the patient 169. A patient with essenti- developed Quincke’s disease; rash al hypertension complains of in the form of blisters and papulae infrequent occurrences of dry cough. appeared on her torso. First aid in Clinical and X-ray examination of this case should start with admini- the respiratory organs revealed no stering the following drug: pathologies. What drug from those taken by the patient can cause cough as a side effect? Кrok 2 Pharmacy (англомовнi студенти) 2016 рiк 21

A. Prednisolone A. Amount and nature of disintegrati- B. Penicillin ng agents C. Fresh frozen plasma B. Poor flowability D. Rheopolyglukin (Dextran) C. High specific gravity of powders E. Haemodes D. Tablet powder contains lamellar crystals 174. A patient with osteoarthritis E. Heterogeneity of granulated (gonarthrosis) and peptic gastric material ulcer in anamnesis should be prescribed a NSAID (nonsteroidal anti- 179. Cytitonum agitates respiratory inflammatory drug). What NSAID center during asphyxiation, state of would be the safest for this patient? shock, intoxication and respiratory arrest. Seeds of a medicinal herb are A. Meloxicam the source of this drug. Name this B. Acetylsalicylic acid herb: C. Ibuprofen D. Indometacin A. Thermopsis lanceolata E. Metamizole sodium B. Linum usitаtissimum C. Plantago psyllium 175. In the course of clinical D. Cucurbita pepo instrumental examination a 45-year- E. Ricinus communis old patient has been diagnosed with chronic helicobacter-associated 180. During qualitative chemical type B gastritis. What group of drugs analysis of nicotinic acid substance should be prescribed first of all? the reaction was conducted, which resulted in blue coloring. What A. Anti-Helicobacter pylori agents reagent was used? B. Prokinetic agents C. Antacids A. Copper (II) sulfate solution D. Reparative drugs B. Sodium hydroxide solution E. Anti-muscarinic agents C. Iron (III) chloride solution D. Thiocyanogen bromide reagent 176. When servicing customers it E. Nessler’s reagent is necessary to maintain cash desk discipline. A cashier should make 181. Pharmaceutical market subjects records in the cash book: that purchase drugs and medical products for further resale to make A. Immediately after the cash aprofit are called: transaction occurred B. Monthly A. Dealers C. Quarterly B. Manufacturers D. Weekly C. Consumer organisations E. At the end of a workday D. Government authorities E. Individual consumers 177. Name the way of injectabulettae application: 182. A pharmaceutical firm is unable to satisfy the demand for a drug. A. For injection solutions of drugs Specify the type of marketing tasked B. Peroral with decrease of excessive demand C. For implantations for a product by raising prices and D. Vaginal stopping advertising and promotion: E. Sublingual 178. What factors affect tablet disi- ntegration? Кrok 2 Pharmacy (англомовнi студенти) 2016 рiк 22

A. Demarketing A doctor suspects osteoporosis B. Creative marketing development. It is necessary to C. Promotional marketing prescribe the patient calcium D. Synchromarketing preparations and: E. Remarketing A. Vitamin D3 183. Cephalosporin structure is based B. B-group vitamins on the condensed system containing C. Vitamin C two cycles - β-lactam and: D. Vitamin A E. Vitamin E A. Dihydrothiazine B. Thiazolidine 188. A pharmacist has made an oil C. Pyrrolizidine emulsion with vitamin E oil solution D. Phenothiazine intended for internal use. What is the E. Pyridine best approach to vitamin introduction into the emulsion? 184. To prepare eyedrops with antibiotic a dispensing chemist has been A. Dissolve in oil before making using flowing steam sterilization primary emulsion under 100oC for 30 minutes. What B. Suspend in the prepared emulsion antibiotic allows for such sterilizati- C. Dissolve in water for emulsion on? dilution D. Dissolve in glycerine A. Levomycetin (Chloramphenicol) E. Dissolve in water to make primary B. Sodium benzylpenicillin emulsion C. Streptomycin sulfate D. Biomycin 189. Name the professional, who is E. Erythromycin authorized to check financial and economic activity of an enterprise at 185. A 48-year-old patient has the request issued by an enterprise undergone incomplete amputation of or public authority: the thyroid gland. Choose the drug for replacement therapy in case of A. Auditor hypothyroidism: B. Chief accountant C. Pharmacy manager A. L-thyroxin D. Inspector B. Hydrocortisone E. Compliance officer C. Insulin D. Metoprolol 190. A 52-year-old patient has been E. Prednisolone diagnosed with gouty arthritis, phase 2. What drug should be basic in 186. Specify the medicinal substance treatment of this patient? with pronounced hydrophobic properties: A. Allopurinol B. Hydrochlorothiazide A. Sulfur C. Paracetamol B. Basic bismuth nitrate D. Furosemide C. Zinc oxide E. Penicillin D. Sodium bromide E. Magnesium oxide 191. Speed of blend powder dampening can be significantly 187. A 34-year-old patient suffering affected by package material. What from systemic lupus erythematosus capsules protect powders from damp takes methylprednisolone. On air the best? examination the patient’s blood calcium is revealed to be low. Кrok 2 Pharmacy (англомовнi студенти) 2016 рiк 23

A. Waxed 196. During the period when a cash B. Parchment register is inoperable and undergoes C. Soft gelatine repairs it is possible to perform D. Polyethylene payment operations using: E. Paper A. Transactions logbook and receipts 192. Anthracene derivatives B. Payment orders have two main directions of C. Check book pharmacological activity: purgative D. Credit and debit cash orders and litholytic. What leads to the di- E. Accompanying notes fference in pharmacological activity of different anthracene derivatives? 197. An analytical chemist performs identification of lidocaine hydrochlori- A. Hydroxyl group placement de. According to the State B. Amount of sugar residues Pharmacopoeia of Ukraine the C. Presence of methyl groups presence of chloride ions can be D. Presence of carboxyl groups confirmed by means of reaction wi- E. Polymerization th silver nitrate solution resulting in: 193. A pharmacy manager has A. White caseous precipitate calculated a certain indicator of effi- B. Green fluorescence ciency of pharmacy’s economic acti- C. Violet coloring vity as percentage ratio of profits to D. Yellow precipitate turnover in retail prices. What indi- E. Blue coloring cator is it? 198. A pharmacist has dissolved a A. Profitability medicinal substance in sterile puri- B. Turnover growth rate fied water to make an eye ointment. C. Turnover expenditure Specify this medicinal substance: D. Inflation rate E. Trade stock standard A. Pilocarpine hydrochloride B. Xeroform 194. A pharmacy sells standard drugs C. Menthol to population. What is a prime cost D. Basic bismuth nitrate of sold goods, if the retail price is 300 E. Purified sulfur 000 UAH, and the total markup is 120 000 UAH? 199. What tax is registered as a local one in a pharmacy budget? A. 180 000 UAH B. 100 000 UAH A. Single tax C. 50 000 UAH B. Corporate income tax D. 120 000 UAH C. Value-added tax E. 300 000 UAH D. Income tax E. Excise tax 195. Pharmacy employees should meet universal qualification requi- 200. An important indicator of busi- rements. Who has the right to hold ness activity is profitability of a busi- a position of a prescription drugs ness. Specify the indices that can be department manager? used to measure the profitability: A. Dispensing chemist A. Profit/turnover B. Pharmacist B. Turnover/cost price C. Sanitary assistant C. Turnover/income D. Packager D. Income/turnover E. Manager E. Liquidity/solvency

INSTRUCTIONAL BOOK

Testing Board

TEST ITEMS FOR LICENSING EXAMINATION: KROK 2. PHARMACY.

Kyiv. Testing Board. (English language).

Approved to print 01.03/№22. Paper size 60х84 1/8 Offset paper. Typeface. Times New Roman Cyr. Offset print. Conditional print pages 16. Accounting publishing pages 20. Issue. 261 copies

List of abbreviations

A/G Albumin/globulin ratio A-ANON Alcoholics anonymous ACT Abdominal computed tomography ALT Alanin aminotranspherase AP Arterial (blood) pressure AST Aspartat aminotranspherase BP Blood (arterial) pressure BR Breathing rate bpm Beats per minute C.I. Color Index CBC Complete blood count CHF Chronic heart failure CT Computer tomography DIC Disseminated intravascular coagulation DCC Doctoral controlling committee DM-2 Non-Insulin dependent diabetes mellitus DTP Anti diphtheria-tetanus vaccine ECG Electrocardiogram ESR Erythrocyte sedimentation rate FC Function class FEGDS Fibro-esphago-gastro-duodenoscopy Gy Gray GIT Gastrointestinal tract Hb Hemoglobin HbA1c Glycosylated hemoglobin Hct, Ht Hematocrit HDL High-density lipoproteins HRIDDM HeartInsulin rate dependent diabetes mellitus IHD Ischemic heart disease IU International unit MSEC Medical and sanitary expert committee NIDDM Non-Insulin dependent diabetes mellitus pCO2 CO2 partial pressure pO2 O2 partial pressure Pm Per minute Ps Pulse rate R Roentgen RBC Red blood count Rh Rhesus RR Respiratory rate S1 (S1) Heart sound 1 S2 (S2) Heart sound 2 TU Tuberculin unit U Unit USI Ultrasound investigation V/f Vision field WBC White blood count X-ray Roentgenogram