Anti-KLRK1 Monoclonal Antibody, Clone 2E22 [PE] (DCABH-6504) This Product Is for Research Use Only and Is Not Intended for Diagnostic Use

Anti-KLRK1 monoclonal antibody, clone 2E22 [PE] (DCABH-6504) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Product Overview Mouse monoclonal to NKG2D (Phycoerythrin)

Antigen Description Receptor for MICA, MICB, ULBP1, ULBP2, ULBP3 (ULBP2> ULBP1> ULBP3) and ULBP4. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Involved in the immune surveillance exerted by T- and B-lymphocytes.

Immunogen Tissue, cells or virus corresponding to Human NKG2D. NKL cell line.

Isotype IgG1

Source/Host Mouse

Species Reactivity Human

Clone 2E22

Purity Size exclusion

Purification Affinity purified

Conjugate PE

Preparation The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use.

Procedure Conjugated Antibodies

Format Liquid

Size 100 μg

Buffer Preservative: 0.1% Sodium azide; Constituents: 99% PBS, 0.2% BSA; BSA is high-grade and protease free.

Preservative 0.1% Sodium Azide

Storage Store at +4°C. Do Not Freeze. Store In the Dark.

Ship Shipped at 4°C.

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Gene Name KLRK1 killer cell lectin-like receptor subfamily K, member 1 [ Homo sapiens ]

Official Symbol KLRK1

Synonyms KLRK1; killer cell lectin-like receptor subfamily K, member 1; D12S2489E, DNA segment on chromosome 12 (unique) 2489 expressed sequence; NKG2-D type II integral membrane protein; CD314; KLR; NKG2 D; NKG2D; NK cell receptor D; NKG2-D-activating NK recepto

Entrez Gene ID 22914

Protein Refseq NP_031386

UniProt ID A0A024RAP8

Chromosome Location 12p13.2-p12.3

Pathway Adaptive Immune System, organism-specific biosystem; Immune System, organism-specific biosystem; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, organism-specific biosystem; Malaria, organism-specific biosystem; Malaria, conserved biosystem; Natural killer cell mediated cytotoxicity, organism-specific biosystem; Natural killer cell mediated cytotoxicity, conserved biosystem;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]