Anti-KLRK1 monoclonal antibody, clone 2E22 [PE] (DCABH-6504) This product is for research use only and is not intended for diagnostic use. PRODUCT INFORMATION Product Overview Mouse monoclonal to NKG2D (Phycoerythrin) Antigen Description Receptor for MICA, MICB, ULBP1, ULBP2, ULBP3 (ULBP2> ULBP1> ULBP3) and ULBP4. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Involved in the immune surveillance exerted by T- and B-lymphocytes. Immunogen Tissue, cells or virus corresponding to Human NKG2D. NKL cell line. Isotype IgG1 Source/Host Mouse Species Reactivity Human Clone 2E22 Purity Size exclusion Purification Affinity purified Conjugate PE Preparation The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. Procedure Conjugated Antibodies Format Liquid Size 100 μg Buffer Preservative: 0.1% Sodium azide; Constituents: 99% PBS, 0.2% BSA; BSA is high-grade and protease free. Preservative 0.1% Sodium Azide Storage Store at +4°C. Do Not Freeze. Store In the Dark. Ship Shipped at 4°C. 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved GENE INFORMATION Gene Name KLRK1 killer cell lectin-like receptor subfamily K, member 1 [ Homo sapiens ] Official Symbol KLRK1 Synonyms KLRK1; killer cell lectin-like receptor subfamily K, member 1; D12S2489E, DNA segment on chromosome 12 (unique) 2489 expressed sequence; NKG2-D type II integral membrane protein; CD314; KLR; NKG2 D; NKG2D; NK cell receptor D; NKG2-D-activating NK recepto Entrez Gene ID 22914 Protein Refseq NP_031386 UniProt ID A0A024RAP8 Chromosome Location 12p13.2-p12.3 Pathway Adaptive Immune System, organism-specific biosystem; Immune System, organism-specific biosystem; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, organism-specific biosystem; Malaria, organism-specific biosystem; Malaria, conserved biosystem; Natural killer cell mediated cytotoxicity, organism-specific biosystem; Natural killer cell mediated cytotoxicity, conserved biosystem; 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved.