Microbiology Society Has Been Publishing Research for , and Now Has a Portfolio of Children Eating Probiotic Yogurt in Mwanza, Tanzania

Total Page:16

File Type:pdf, Size:1020Kb

Microbiology Society Has Been Publishing Research for , and Now Has a Portfolio of Children Eating Probiotic Yogurt in Mwanza, Tanzania Microbiology Annual Conference 2019 8–11 APRIL, BELFAST WATERFRONT, UK TODAY 45:3 August 2018 Microbiology 45:3 Microbes Today August 2018 and Food Registration and abstract submission open August 2018 Abstract submission deadline: 10 December 2018 Grants deadline: 31 January 2019 Registration closes: 11 March 2019 @MicrobioSoc #Microbio19 Discover more at: microbiologysociety.org/annualconference Email: [email protected] Microbes and Food Using microbes to influence flavour production Microbial diversity in the digestive tract of herbivores Join over 1,400 delegates for three and a half days of Mycoprotein production and food sustainability Foodborne diseases: sequencing for answers presentations, posters and networking. Bacteriophage therapy in livestock: food for thought? Conference Flyer 2019 A4 v5.indd 1 17/04/2018 10:39 5 REASONS Since 2004, I have been committed to giving people in Africa access to probiotics. With amazing colleagues, we are now providing the opportunity for everyday citizens in TO PUBLISH WITH US villages and towns in Tanzania, Kenya and Uganda to produce probiotic fermented food (www.yoba4life.org, www.westernheadseast.ca). WE ARE A LEADING PUBLISHER IN THE These efforts are reaching over FIELD OF MICROBIOLOGY 250,000 people, while in Argentina, a wonderful school programme is doing The Microbiology Society has been publishing research for , and now has a portfolio of Children eating probiotic yogurt in Mwanza, Tanzania. Gregor Reid 69 years 1 the same through a locally discovered six peer-reviewed journals, with over 3,500 articles submitted in 2015. our hospital instituting probiotics as experiments in mice. I suspect less than probiotic yogurt. standard therapy for premature, low 10% of these projects ever make the birth weight newborns, and while the slightest dent in that disease. If we truly Imagine the possibilities! rate of NEC was not overly high at want to understand health and prevent It’s a microbial world, and WE ARE A NOT-FOR-PROFIT ORGANISATION around 3% beforehand, it’s almost zero and treat disease, we need to direct probiotics have an important place Unlike commerical publishers, we invest our publishing surplus to advance the understanding now. The ultimate in clinical translation. funding to studying and replenishing in it. Imagine what we could do as a and impact of microbiology by connecting and empowering communities worldwide, through: But probiotics are not a silver bullet. beneficial microbes in humans. collective? 2 international conferences, professional development, policy, education and outreach. They may never reduce cholesterol as much as statins, but they won’t cause Gregor Reid muscle wasting and terrible side effects. University of Western Ontario, Lawson Health Research They reduce colic in breast-fed babies, Institute, Rm F3-106, 268 Grosvenor Street, London, Ontario WE OFFER FAST AND RIGOROUS reduce the duration of diarrhoea and N6A 4V2, Canada PEER REVIEW respiratory infections and recurrence of e [email protected] UTI. What else can enhance immunity, Gregor Reid is Professor of Microbiology and Immunology, Our Editors and Reviewers provide unbiased, invaluable critical thinking and analysis to ensure 3 reduce side effects of HIV/AIDS and high-quality papers are accepted for publication. Average time to first decision is4–6 weeks, and our Reid Gregor and Surgery at The University of Western Ontario. He has many other drugs, reduce stunting and authors rate the peer review process 4 out of 5. published 520 peer-reviewed papers, been awarded 28 patents and given over improve maternal and infant health? 600 talks in 54 countries. He has many awards, including an Honorary Doctorate In the late eighties I had a grant from Orebro University in Sweden, and being appointed to the Royal Society of rejected on probiotics to prevent UTI with Canada and the Canadian Academy of Health Sciences. OUR JOURNALS HAVE EXPERT a reviewer stating, “why are you doing this when we have antibiotics?” While INTERNATIONAL EDITORIAL BOARDS we now suffer the penalties of excessive What is the most enjoyable bit of your job? 4 Our influential Editors and Editorial Board members are selected antibiotic use, my only satisfaction from The highs. They come in many forms (discoveries, papers accepted, grants won, for their knowledge, expertise and contribution to the microbiology community. rejection is seeing many of these grant awards, student successes, invitations to speak, people personally benefiting panellists now studying probiotics. We from probiotics, etc.), and you need them to offset the lows which are sadly must be doing something right. inevitable in science. What advice would you give to someone starting out in this field? YOUR RESEARCH PUBLISHED ON A NEW AND Translation means to all people, not just the rich Find something to believe in that is real, and make it part of your life. The concept INTERACTIVE JOURNAL PLATFORM of lactobacilli being beneficial for the female urogenital tract made sense from Of the thousands of grants I have read, day one, and made even more sense the more I studied it. I was relentless in its Authors benefit fromenhanced article level metrics so they know where their research is being 5 almost all start with stating a clinical discussed online and how many times their article has been downloaded. Our journals have a pursuit, making the data be the marker, not mythical ideas. Passion is critical if problem their project relates to then global readership, so your article is highly discoverable and citable. what you are passionate about has a foundation in stone, not sand. many describe so-called ‘mechanistic’ Find out more about our journals at microbiologyresearch.org Microbiology Today Aug 18 | www.microbiologysociety.org 149 Editorial Welcome to the August edition of Microbiology Today, hopefully one you are able to enjoy in the summer sun, possibly alongside a cold drink or an ice cream. If you are enjoying this issue with a snack, it is worth stopping for a moment to consider how microbes might be impacting on your experience of that food. Whole Picture icrobes influence our food in digestive tract of ruminants reared for health as well as human health, Prerna an extensive range of ways, human consumption are of particular explains how sequencing technology Mdictating whether or not you commercial interest, as they can impact is being utilised to provide valuable experience a delicious flavour or will be on the energy available for the growth information on the virulence and sick as a result of what you eat. They can of those animals and can also alter zoonotic potential of these microbes. be utilised to produce protein and can greenhouse gas production. With this in mind, up next are the impact on the health of livestock that Given that the production of the microbes which could have a role in are an essential part of the food chain. In food we eat comes at a cost, both helping to combat infection in livestock. this edition we look at all the wonderful monetary and environmental, it is Robert Atterbury turns our attention to and not so wonderful ways in which becoming increasingly important to bacteriophage and the ways in which microbes affect our food. look at lower-cost alternatives. Richard these viruses could be used to reduce To start us off on our journey looking Harrison and Rob Johnson walk us infection and antibiotic use in animals into microbes and food, Christine Dodd through the production of low-carbon destined for the food chain, potentially and Dewi Yunita explain how microbes protein made by fungi and how it can creating a knock-on effect for human can influence the complexity and variety be consumed globally as an alternative health. of flavours and textures in the foods we to meat. Discussing some of the To finish off, Gregor Reid helps eat. Covering a wide diversity of food reasons for the increased demand for us all out with his Comment piece on products, they explain how microbes this type of protein, they outline its probiotics. Answering the questions, can direct flavour development and how origins, manufacture and the direction “what are probiotics and which one using the right starter culture plays a of research which will support an should I take?”, Gregor provides us with major role in producing the desirable increasingly energy-efficient product in an insight into the evidence for some flavours that we come across every day. the future. of the probiotics available to the public As well as being used directly Despite the many positive roles and highlights the impact probiotics can to flavour our food, microbes also microbes can have in food production, have in clinics when used appropriately. impact our food choices through the there are still those few microbes which He also describes how production role they play as an essential part of can cause us distress in the form of of probiotics is being used to benefit the digestive tract of herbivores. Neil foodborne disease. The symptoms human populations on a global scale. McEwan describes how the relationship can range from mild through to life- between host and microbe allows the threatening, and some of the microbes Rowena Jenkins host to utilise nutrients from plants causing these problems are considered Editor that they would be unable to process here by Prerna Vohra. Reminding us that [email protected] alone. The microbes present in the these microbes can impact on animal Microbiology Today Aug 18 | www.microbiologysociety.org 101 Contents Microbiology TODAY Articles A matter of taste: using microbes to 110 influence flavour production Christine Dodd & Dewi Yunita The tastes of different microbes. Microbial diversity in the digestive tract 114 of herbivores Neil McEwan Symbiosis between herbivores and micro-organisms. Mycoprotein production and food 118 sustainability Richard Harrison & Rob Johnson Mycoprotein development and production.
Recommended publications
  • Annual Conference Abstracts
    ANNUAL CONFERENCE 14-17 April 2014 Arena and Convention Centre, Liverpool ABSTRACTS SGM ANNUAL CONFERENCE APRIL 2014 ABSTRACTS (LI00Mo1210) – SGM Prize Medal Lecture (LI00Tu1210) – Marjory Stephenson Climate Change, Oceans, and Infectious Disease Prize Lecture Dr. Rita R. Colwell Understanding the basis of antibiotic resistance University of Maryland, College Park, MD, USA as a platform for early drug discovery During the mid-1980s, satellite sensors were developed to monitor Laura JV Piddock land and oceans for purposes of understanding climate, weather, School of Immunity & Infection and Institute of Microbiology and and vegetation distribution and seasonal variations. Subsequently Infection, University of Birmingham, UK inter-relationships of the environment and infectious diseases Antibiotic resistant bacteria are one of the greatest threats to human were investigated, both qualitatively and quantitatively, with health. Resistance can be mediated by numerous mechanisms documentation of the seasonality of diseases, notably malaria including mutations conferring changes to the genes encoding the and cholera by epidemiologists. The new research revealed a very target proteins as well as RND efflux pumps, which confer innate close interaction of the environment and many other infectious multi-drug resistance (MDR) to bacteria. The production of efflux diseases. With satellite sensors, these relationships were pumps can be increased, usually due to mutations in regulatory quantified and comparatively analyzed. More recent studies of genes, and this confers resistance to antibiotics that are often used epidemic diseases have provided models, both retrospective and to treat infections by Gram negative bacteria. RND MDR efflux prospective, for understanding and predicting disease epidemics, systems not only confer antibiotic resistance, but altered expression notably vector borne diseases.
    [Show full text]
  • Table of Contents
    Table of Contents Verbal Presentations Verbal Presentations – Monday………………………………………………………...................... Page 2 Verbal Presentations – Tuesday……………………………………………………………………… Page 17 Verbal Presentations – Wednesday………………………………………………………..…….….. Page 32 Verbal Presentations – Thursday……………………….……………………………….………..…. Page 46 Poster Presentations Poster Presentations – Monday…………………………………………………………………..…. Page 52 Poster Presentations – Tuesday……………………………………………………………..……… Page 64 Poster Presentations – Wednesday……………………………………………………….……….. Page 77 Poster Presentations – Thursday……………………………………….………………….……….. Page 90 Page 1 of 99 Verbal Presentations Monday, May 15th 8:30 – 10 AM Grumman A Microsimulation Approach to Estimating Annual Risk in QMRA. Coping with Non-Random Variation in Risk Amongst Populations Paul Hunter, The Norwich Medical School, University of East Anglia Additional Author: James Maas Most QMRA studies have focused on refining the estimation of the daily risk comparatively little thought has been given to estimating the annual risk. As pointed out by Karavarsamis and Hamilton most studies have used a relatively simple method of estimating annual risk from the distribution of daily risks, namely 1-(1-Pd)^365 (1). This approach essentially assumes that the daily risk is constant through the year and Karavarsamis and Hamilton, with justification, refer to this approach as "Naϊve". Instead they propose a stochastic approach that essentially samples the distribution of daily risks and then calculates the annual risk as 1-the product of (1- 365 randomly sampled daily risk), calling this the "Gold Standard Approach". We argue that Karavarsamis and Hamilton's gold standard approach is also naϊve. Daily risks in any one individual are neither constant through a year nor are they entirely random. For example, across a population some people drink a lot of water each day and others drink very little. Other factors like the concentration of pathogen in a supply may vary much more randomly.
    [Show full text]
  • Holding Hands with Bacteria the Life and Work of Marjory Stephenson
    SPRINGER BRIEFS IN MOLECULAR SCIENCE HISTORY OF CHEMISTRY Soňa Štrbáňová Holding Hands with Bacteria The Life and Work of Marjory Stephenson 123 SpringerBriefs in Molecular Science History of Chemistry Series editor Seth C. Rasmussen, Fargo, North Dakota, USA More information about this series at http://www.springer.com/series/10127 Soňa Štrbáňová Holding Hands with Bacteria The Life and Work of Marjory Stephenson 1 3 Soňa Štrbáňová Academy of Sciences of the Czech Republic Prague Czech Republic ISSN 2191-5407 ISSN 2191-5415 (electronic) SpringerBriefs in Molecular Science ISSN 2212-991X SpringerBriefs in History of Chemistry ISBN 978-3-662-49734-0 ISBN 978-3-662-49736-4 (eBook) DOI 10.1007/978-3-662-49736-4 Library of Congress Control Number: 2016934952 © The Author(s) 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication.
    [Show full text]
  • Microbiology Society Activities
    MICROBIOLOGY TODAY 48:1 May 2021 Microbiology Today 48:1 May 2021 Life on a Changing Planet Life on a Changing Planet Exploring the relationship between climate change and the microbial world Forest Fire in Dixie National Forest, Utah, USA. santirf/iStock which in turn increase the risk of COVID-19 complications. impact on respiratory health of affected communities. Curr Opin Pulm Wildfire smoke exposure might also increase the likelihood of Med 2019;25:179–187. comorbidities, including cardiovascular diseases, respiratory Wu X, Nethery RC, Sabath MB, Braun D, Dominici F. Air pollution and diseases, diabetes and hypertension, leading to an increased COVID-19 mortality in the United States: strengths and limitations of an ecological regression analysis. Sci Adv 2020;6:eabd4049. COVID-19 risk. Higher daily average PM2.5 concentrations during the wildfire season in western US states were positively Gosling SN, Bryce EK, Dixon PG, Gabriel KMA, Gosling EY et al. associated with increased influenza rates the following A glossary for biometeorology. Int J Biometeorol 2014;58:277–308. winter, indicating strong evidence for delayed effects of wildfire exposure. Research on understanding the underlying mechanisms between wildfire exposure and respiratory Rosa von Borries infection is an area of active investigation. Consultant at World Meteorological Organization, In particular, vulnerable population groups such as socio- Bernhard-Lichtenberg-Str 15, 10407 Berlin, economically disadvantaged populations, individuals with Germany comorbidities and the elderly face higher risks of experiencing [email protected] the combined consequences of COVID-19 and wildfires. @rosavborries In the US, migrant farmworkers who were continuously linkedin.com/in/rosa-von-borries-5b4987197 exposed to wildfire smoke and deemed essential workers during the pandemic faced much higher risks of severe Rosa von Borries holds an MSc in Public Health from London School health consequences from wildfire smoke and COVID-19.
    [Show full text]
  • The Foot-And-Mouth Disease Virus Replication Complex
    The Foot-and-Mouth Disease Virus Replication Complex: Dissecting the Role of the Viral Polymerase (3Dpol) and Investigating Interactions with Phosphatidylinositol-4-kinase (PI4K) Eleni-Anna Loundras Submitted in accordance with the requirements for the degree of Doctor of Philosophy The University of Leeds School of Molecular and Cellular Biology August 2017 The candidate confirms that the work submitted is her own, except where work which has formed part of jointly authored publications has been included. The contribution of the candidate and the other authors to this work has been explicitly indicated below. The candidate confirms that appropriate credit has been given within the thesis where reference has been made to the work of others. The work appearing in Chapter 3 and Chapter 4 of the thesis has appeared in publications as follow: • Employing transposon mutagenesis in investigate foot-and-mouth disease virus replication. Journal of Virology (2015), 96 (12), pp 3507-3518., DOI: 10.1099/jgv.0.000306. Morgan R. Herod (MRH), Eleni-Anna Loundras (EAL), Joseph C. Ward, Fiona Tulloch, David J. Rowlands (DJR), Nicola J. Stonehouse (NJS). The author (EAL) was responsible for assisting with preparation of experiments and production of experimental data. MRH, as primary author drafted the manuscript and designed the experiments. NJS and DJR conceived the idea, supervised the project, and edited the manuscript. • Both cis and trans activities of foot-and-mouth disease virus 3D polymerase are essential for viral replication. Journal of Virology (2016), 90 (15), pp 6864-688., DOI: 10.1128/JVI.00469-16. Morgan R. Herod, Cristina Ferrer-Orta, Eleni-Anna Loundras, Joseph C.
    [Show full text]
  • Qumrter{Y Rn{-}#R.}Rin* Nf Thw S**:Imty Rnicrr:Hl*I*E5r
    F r-nierobiologytodcly i W; vol33i oug06 ,: qumrter{y rn{-}#r.}rin*nf thw s**:imty f'*r 6*[":*l"C*l rnicrr:hl*i*E5r I f vcl33(3) [*j'l-l l.-ili:i i" t'.ir'iliL.i i{:}li 90 News 128 Cradline 134 Reviews 122 Meetings 130 Hotoff the press 139 Addresses 124 Schoolzone132 Coingpublic it'l i:)'i-:il;I i i i::ji-i-l:; 117 Usingmicroscopy to enhanceundergraduate teaching 127 Letter 136 obituaries i:l l'Tl{,-li:}S 96 Fluorescencemicroscopy Canyou seethe asa researchtool in bacterial light? cellbiology lain Hagan , AgnesCrallert & Jeff Errington SteveBagley The revolution of new views of the subcellularorganization Simpleand affordable steps to exploitrecent of bacteria. advancesin ffuorescenceimaging. 100 |nvestigating a bacterial killer usingatomic force microscopy 118 HenryBaker: author of the MeganNufiez & EileenSpain first m icroscopy labo ratory Learnabout the secretlife of the predatorykiller, Bdellovibrio. manual Virusesand intracellular RichardBurns This18th century polymath played a big partin popularizing movement earlymicroscopes. TomWileman How do virusesmanaSe to move within and between the cellsof their host? Comment - Openoption for SCM 108 Studyingsingle molecules in journals microbialsystems RonFraser & RobinDunford ChristophBaumann Openaccess demands by grant-awardingbodies Individualmolecules in livingcells can now be observed. arecausing problems for publishers. {ovr:r inoge Microscopelenses. Tony Craddock / SciencePhoto Library Theviews expressed fditr.rrDrCavinThomas[lcii|*riili{l*"lrdDr5ueAssinder'Professor|ainHagan,ProfessorBertRlma
    [Show full text]
  • 70Th Anniversary Collection of the Microbiology Society: Journal of General Virology Robin A
    Journal of General Virology (2015), 00, 1–3 DOI 10.1099/jgv.0.000286 Commentary 70th Anniversary Collection of the Microbiology Society: Journal of General Virology Robin A. Weiss Correspondence Division of Infection & Immunity, University College London, London WC1E 6BT, UK Robin A. Weiss [email protected] To mark the 70th anniversary of the founding of the Society From its inception, the Journal of General Virology took for General Microbiology (now renamed the Microbiology papers on the structure and design of virus particles, Society) it was decided to showcase 70 salient publications such as human adenovirus type 5. In a superb biochemical from the archives of its various journals. The Journal of Gen- and structural analysis comprising three consecutive eral Virology was allocated 15 papers. I was invited to curate papers, the second paper by Russell et al. (1967) showed them and given a carte blanche which ones to choose. True that when heated to 56 8C, the icosahedral capsid ruptured to the name of the journal, I picked a broad range of viruses at the penton bases and liberated viral DNA. They also cor- and a paper on prion disease. If readers are disappointed not rectly predicted that unknown nucleocore proteins exist to see their own most cherished contribution featured that in later years became important for understanding among them, please consider the odds: only 15 from over cell transformation and early steps in virus replication. 15 000 Journal of General Virology articles could be selected The only paper among the 15 selected that does not present and I gave more weight to older papers to recall contri- primary research data is the commentary on virus diversity butions by the pioneers of virology.
    [Show full text]
  • Microbiologytoday Biology and Pathogenesis Current Technology and Author: Naveed Khan Molecular Biology Applications
    Caister Academic Press New Books for 2009 www.caister.com Acanthamoeba Lactobacillus Real-Time PCR microbiologytoday Biology and Pathogenesis Current Technology and Author: Naveed Khan Molecular Biology Applications ... available now! c. 220 pp., February 2009 From Genomics to Probiotics Edited by: J. Logan, K. Edwards and N. Saunders ISBN: 978-1-904455-43-1 $310 / £150 Edited by: Åsa Ljungh and Torkel Wadström x + 284 pp., January 2009 The first comprehensive review of c. 220 pp., January 2009 ISBN 978-1-904455-39-4 $310 / £150 Acanthamoeba research to be published. ISBN 978-1-904455-41-7 $310 / £150 A comprehensive guide to the latest PCR The current state of research on every aspect An essential reference for all dairy of this organism, detailing major advances platforms, fluorescent chemistries, validation technologists, microbiologists and in areas such as genomics, molecular and software, data analysis, internal and external cellular biology, life cycles, geographical biotechnologists. Includes phylogenetics, controls and a wide range of applications: distribution, role in ecosystem, morphology, taxonomy, comparative genomics, functional clinical diagnostics, biodefense, RNA vol35|nov08 genomics, the intestinal microflora, surface motility, phylogenetics, genotyping, metabolism, expression studies, validation of array data, quarterly regulation of morphogenesis, host-parasite proteins, stress responses, interaction with mutation detection, food authenticity and interactions, the molecular and immunological the immune system, probiotics, anti-cancer legislation, NASBA, and molecular halotyping. basis of pathogenesis, methods of transmission, potential, and much more. Essential reading for magazine of epidemiology, clinical manifestation, diagnosis, all scientists involved with lactic acid bacteria treatment, new target development and drug or probiotic research and a recommended book the society resistance.
    [Show full text]
  • Downloaded from the SGM Website
    F I: t' SGMHeadquarterc MarlborouqhHouse. Articles Basingsto[eRoad, Spencers Thingsthat go rotin the night - Wood,Reading RG7 lAG Tel.01 18 988 1800 a reviewof biodeteriorationGlyn Morton 103 Fax01 189885656 [email protected] Everythingyou wanted to knowaboutthe dry-rot SGMWebsite fungusbutwere afraid to askJohnW Palfreyman http:./www.sgm.ac.uk &NiaA.White 107 Editor Lichens,agents of monumentaldestruction DrMerielJones MarkR.D.Seaward 110 EditorialBoard ProfessorDave Kelly Conservationof monu m ental stones bv bacterial ProfessorTonyNash biomineralizationBrunetla Perito &Giorgio Mastromei 1 13 ManagingEditor JanetHurst Sulfate-red uci n g bacteriain biofiI ms on metalIic Production Editor materialsand corrosion lwonaB. Beech 11 5 lanAtherton AssistantEditorand TheBiodeterioration Centre, University of Herbfordshire BookReviewManager RichardSmith 1 18 JaniceMeekings Pilzkrieg :the German warti me quest for penicil lin Gontributions Theseare always welcome and GilbertShama 120 shouldbe addressed tothe Editor AcuteRespi ratory rome(SARS) (c/o SGM Headquarters), Severe Synd FaveJones 124 CopyDates Lastdates for receipt of copy atMarlborouqh House are aeneratuopv Regular Featunes November2003 issue 1 Sept Februarv2004 issue 8 December MicroShorts 117&141 AOVerUSemen$ (LKl-.l November2003 issue 29 Sept SocietyNews February2004 issue1 9 January MayCouncilMeeting 126 Advertisements Above:Ascanning usuallycaused bysulfate- NewsofMembers 126 (SRB) Allenquiriesshould be sentto: electronmicrograph of the reducingbacteria and StaffNews 126 Domin
    [Show full text]
  • Microbiologytoday
    microbiologytoday microbiology vol36|feb09 quarterly magazine of the society today for general microbiology vol 36 | feb 09 the legacy of fleming ‘that’s funny!’: the discovery of penicillin what manner of man was fleming? the future of antibiotic discovery look who’s talking when good bugs fight bad contents vol36(1) regular features 2 News 38 Schoolzone 46 Hot off the Press 10 Microshorts 42 Gradline 49 Going Public 36 Conferences 45 Addresses 60 Reviews other items 33 The Defra-commissioned independent review of bovine tuberculosis research 54 Education Development Fund report 58 Obituary – Professor Sir James Baddiley FRS 59 Obituary – Emeritus Professor Naomi Datta FRS articles 12 ‘That’s funny!’: the 24 Look who’s talking! discovery and development Julian Davies of penicillin Antibiotics aren’t just for fighting infections; they are part of the bacterial signalling network. Kevin Brown The chance discovery of penicillin 80 years ago made Alexander Fleming a famous scientist. 28 When good bugs fight bad Roy Sleator 16 What manner of man was There are alternative methods available Alexander Fleming? for combating infectious diseases – not just antimicrobial chemotherapy. Philip Mortimer Alexander Fleming, the Society’s first President, did so much more than discover penicillin. 32 A precious memory Norberto Palleroni One of the few people left who met Fleming recounts his 20 Antibiotics and experience. Streptomyces: the future of antibiotic discovery 64 Comment: Debating creationism Flavia Marinelli Many options for drug discovery
    [Show full text]
  • Microbiology Society
    MICROBIOLOGY TODAY 47:1 May 2020 Microbiology Today May 2020 47:1 Why Microbiology Matters – 75th anniversary issue Why Microbiology Matters We are celebrating our 75th anniversary by showcasing why microbiology matters and the impact of microbiologists past, present and future. MICROBIOLOGY TODAY 47:1 May 2020 Microbiology Today May 2020 47:1 Why Microbiology Matters – 75th anniversary issue Why Microbiology Matters We are celebrating our 75th anniversary by showcasing why microbiology matters and the impact of microbiologists past, present and future. Editorial Welcome to Microbiology Today, which has a new look. This issue is the first of two special editions of the magazine to be published in the 75th anniversary year of the Microbiology Society. As we look back and celebrate during 2020, we are also considering ‘Why Microbiology Matters’. The longer you think about it, the more you realise how in so many ways it does. Whole Picture ince the first observations of microbes by Antonie van thrive in extreme conditions and are found in every niche Leeuwenhoek in the 1600s, our understanding of how around the globe. Smicrobes underpin and impact our lives has advanced Part of the reason for the success of microbes in these considerably. From discovering their life cycles and roles within varied environments is their genetic plasticity. Charles Dorman various environmental niches to harnessing them in industrial introduces the next section on microbial genetics and the role processes, and, not least, our ability to utilise them for good, to it has played in advancing modern biotechnology. From the vaccinate and treat diseases, with many diseases now known original discovery of restriction enzymes through to potential to be caused by microbes.
    [Show full text]
  • How Sialic Acid Impacts
    Microbiology TODAY Microbiology Metabolism, 46:2 Today May 2019 Health and Disease 46:2 May 2019 Metabolism, Health and Disease Where bacterial metabolism and virulence intersect How sialic acid impacts on metabolism, health and disease Modelling virus infections of the skin in 3D Human noroviruses and gut bacteria: friends, frenemies or both? The intestinal microbiota in health and disease health and disease are yet to be Ghannoum M, The Scientist. The investigated, and who knows what Mycobiome;2016. https://www.the-scientist. Why does microbiology matter? implications these will hold for human com/features/the-mycobiome-34129 Farhana: Microbes include a hugely health. [accessed 26 February 2019]. versatile range of organisms. They Hall RA, Noverr MC. Fungal interactions with are integral to the functioning of most Further reading the human host: exploring the spectrum of ecosystems, yet we are still in our Dhamgaye S, Qu Y, Peleg AY. Polymicrobial symbiosis. Curr Opin Microbiol 2017;40:58–64. infancy in understanding their impact. infections involving clinically relevant Gram- Quinton, J. Fungal mediated innate immune Courtney: Micro-organisms coat every negative bacteria and fungi. Cell Microbiol memory, what have we learned? Semin Cell surface around us, on us, and in 2016;18:1716–1722. Dev Biol, in press. our bodies. By understanding how microbes function and how they can Courtney Kousser impact us, we can better learn how to Institute of Microbiology and Infection, School of Biosciences, work with them or fight them. University of Birmingham, Edgbaston, Birmingham B15 2TT, UK Rebecca: Studying all aspects of e [email protected] microbiology is important to enhance @cakousser our understanding and to make new Courtney Kousser is a fourth year PhD student in Dr Rebecca discoveries.
    [Show full text]