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Microbiologytoday Biology and Pathogenesis Current Technology and Author: Naveed Khan Molecular Biology Applications Caister Academic Press New Books for 2009 www.caister.com Acanthamoeba Lactobacillus Real-Time PCR microbiologytoday Biology and Pathogenesis Current Technology and Author: Naveed Khan Molecular Biology Applications ... available now! c. 220 pp., February 2009 From Genomics to Probiotics Edited by: J. Logan, K. Edwards and N. Saunders ISBN: 978-1-904455-43-1 $310 / £150 Edited by: Åsa Ljungh and Torkel Wadström x + 284 pp., January 2009 The first comprehensive review of c. 220 pp., January 2009 ISBN 978-1-904455-39-4 $310 / £150 Acanthamoeba research to be published. ISBN 978-1-904455-41-7 $310 / £150 A comprehensive guide to the latest PCR The current state of research on every aspect An essential reference for all dairy of this organism, detailing major advances platforms, fluorescent chemistries, validation technologists, microbiologists and in areas such as genomics, molecular and software, data analysis, internal and external cellular biology, life cycles, geographical biotechnologists. Includes phylogenetics, controls and a wide range of applications: distribution, role in ecosystem, morphology, taxonomy, comparative genomics, functional clinical diagnostics, biodefense, RNA vol35|nov08 genomics, the intestinal microflora, surface motility, phylogenetics, genotyping, metabolism, expression studies, validation of array data, quarterly regulation of morphogenesis, host-parasite proteins, stress responses, interaction with mutation detection, food authenticity and interactions, the molecular and immunological the immune system, probiotics, anti-cancer legislation, NASBA, and molecular halotyping. basis of pathogenesis, methods of transmission, potential, and much more. Essential reading for magazine of epidemiology, clinical manifestation, diagnosis, all scientists involved with lactic acid bacteria treatment, new target development and drug or probiotic research and a recommended book the society resistance. This book is the definitive guide to Clostridia ... available now! current research on this increasingly important for all microbiology laboratories. Molecular Biology in the Post- for general organism. ... available now! genomic Era Edited by: H. Brüggemann and G. Gottschalk microbiology Mycobacterium x + 230 pp., January 2009 Genomics and Molecular Biology ISBN 978-1-904455-38-7 $310 / £150 Bacterial Secreted Edited by: Tanya Parish and Amanda Brown The first coherent picture of the organism's viii + 214 pp., January 2009 molecular and cellular biology in this post- Proteins ISBN 978-1-904455-40-0 $310 / £150 genomic era. Include botulinum and tetanus Secretory Mechanisms and Role in Expert scientists critically review the current neurotoxins, C. difficile large exotoxins, C. Pathogenesis and most recent advances in the genomics and perfringens enterotoxin, pore-forming and Edited by: Karl Wooldridge molecular biology of mycobacteria. The focus binary bacterial toxins, molecular epidemiology, c. 550 pp., April 2009 is on the topical and most relevant aspects metabolic networks, genetic knock-out systems, ISBN: 978-1-904455-42-4 $310 / £150 and the authors aim to give readers an insight surface structures, anti tumor potential, and Extensive publication on bacterial secreted into the current understanding of the subject antibiotic resistance determinants. proteins, secretory systems and their vital role and the future direction of research. Topics in bacterial pathogenesis. Immense value covered include strain variation and evolution, to all microbiologists, molecular biologists, hypervirulent strains, electron transport and public health scientists and other researchers Plant Pathogenic respiration, lipid biosynthesis, DNA repair, and professionals engaged in the study ... available now! of pathogenesis, drug design and vaccine oxygen signaling, sulphur metabolism, protein Bacteria development. A skillful selection of topics and secretion, the protein kinase family, and Genomics and Molecular Biology a panel of acknowledged experts as authors much more. A valuable reference text for all Edited by: Robert W. Jackson have ensured that this volume will become an microbiology laboratories and essential reading xii + 330 pp., January 2009 important reference source for many years to for all scientists and researchers involved with ISBN 978-1-904455-37-0 $310 / £150 come. mycobacteria. An invaluable, up-to-date summary of the molecular biology and genomics of plant pathogenic bacteria. Includes: bacterial Other Books of Interest evolution, diversity and taxonomy, adaptation, Agrobacterium, Leifsonia, Pectobacterium, • Plasmids: Current Research and Future Trends Pseudomonas, Ralstonia, Xanthomonas, and • Pasteurellaceae: Biology, Genomics and Molecular Aspects Xylella, MAMPs and innate immunity, virulence • Vibrio cholerae: Genomics and Molecular Biology factors, regulation, plasmids and bioinformatics. • Pathogenic Fungi: Insights in Molecular Biology • Helicobacter pylori: Molecular Genetics and Cellular Biology ... available now! • Corynebacteria: Genomics and Molecular Biology FULL DETAILS AT Microbial • Staphylococcus: Molecular Genetics • Leishmania: After The Genome Production of • Archaea: New Models for Prokaryotic Biology WWW.CAISTER.COM • Legionella: Molecular Microbiology Biopolymers and • RNA and the Regulation of Gene Expression: A Hidden Layer of Complexity • Molecular Oral Microbiology Polymer Precursors • Epigenetics Applications and Perspectives • Animal Viruses: Molecular Biology Edited by: Bernd H. A. Rehm bugs on bugs • Segmented Double-Stranded RNA Viruses: Structure and Molecular Biology x + 294 pp., January 2009 microbial diseases of bees • Acinetobacter Molecular Biology ISBN 978-1-904455-36-3 $310 / £150 • Pseudomonas: Genomics and Molecular Biology Describes the most important biopolymers produced by microorganisms. Chapters provide fungal farmers of the insect world a molecular insight into biosynthesis pathways, wolbachia and gene transfer For more details or to order any of these books visit our website physical properties and industrial production www.caister.com processes. Includes metabolic engineering. shedding light on photorhabdus ORDER FROM (UK/Europe): Caister Academic Press, c/o Book Systems Plus, BSP House, Station Road, Linton, Cambs CB21 4NW, UK an inside job – bdellovibrio Tel: 01223 894870 Fax: 01223 894871 http://uk.caister.com ORDER FROM (USA): Caister Academic Press, c/o ISBS, Inc., 920 NE 58th Avenue, Suite 300, Portland OR 97213-3786, USA nature’s experiment – bacteriophages Tel: 503 287-3093 Fax: 503 280-8832 http://usa.caister.com contents vol35(4) regular features 159 News 202 Schoolzone 212 Hot off the Press 166 Microshorts 206 Gradline 215 Going Public 199 Conferences 209 Addresses 218 Reviews other items 196 National Subject Profiles 210 Obituary – Professor Chris Thurston articles 168 Microbial diseases of bees 184 An inside job: Bdellovibrio Travis Glare & Maureen O’Callaghan bacteriovorus Bees play an essential role in the world’s ecosystems, but Liz Sockett microbial diseases are posing a big threat to these vital These predatory bacteria hunt down and eat their fellow insects. organisms. 172 Ancient fungal farmers 188 Bacteriophages: nature’s most of the insect world successful experiment Garret Suen & Cameron Graham Hatfull Currie Phages could well be the world’s biggest reservoir of Leaf-cutter ants not only grow fungi to eat. They unidentified genetic material. weed their ‘gardens’ and apply pesticides too. 192 1983: a vintage year for 176 Bacterial sequences in an pathogen discovery invertebrate genome Robin Weiss Important findings about three major infectious Julie Dunning Hotopp & Jason Rasgon diseases were made 25 years ago. Some arthropods and nematodes need their bacterial inhabitants to survive. 220 Comment: 180 Photorhabdus: shedding light Scotoma in contemporary on symbioses microbiology Susan Joyce and David Clarke Howard Gest Which amazing microbe can make nematodes glow in the Are some bacteria really ‘unculturable’? Probably not dark and yet kill certain insects? according to this writer. Cover image Macrophotograph of the head of a worker honey bee (Apis mellifera). Dr Jeremy Burgess / Science Photo Library The views expressed Editor Dr Matt Hutchings––Editorial Board Dr Sue Assinder, Dr Paul Hoskisson, Professor Bert Rima––Managing Editor Janet Hurst––Assistant Editors Lucy Goodchild & Faye Stokes by contributors are not Editorial Assistant Yvonne Taylor––Design & Production Ian Atherton––Contributions are always welcome and should be addressed to the Editor c/o SGM HQ, Marlborough House, necessarily those of the Basingstoke Road, Spencers Wood, Reading RG7 1AG–Tel. 0118 988 1809–Fax 0118 988 5656–email [email protected]–web www.sgm.ac.uk Society; nor can the Advertising David Lancaster, Ten Alps Publishing, London Office, 10 Savoy Street, London WC2E 7HR–t 0207 878 2316–f 0207 379 7118–e [email protected] Regular feature images pp. 159 SGM; 203, 219 Comstock / Jupiter Images; 207, 213 Stockbyte; 209 Digital Vision / Getty claims of advertisers © 2008 The Society for General Microbiology––ISSN 1464-0570––Printed by Latimer Trend & Company Ltd, Plymouth, UK be guaranteed. Set your PhD on the right track with a New Student NEB Starter Pack news FREE New SGM Prize Medal Surveys on Open Access Journals to all new research Stanley B. Prusiner accepts award for 2009 I represent SGM on the Biosciences Federation (BSF) Journals SGM is pleased to announce that Dr Stanley B. Prusiner, Committee. We have recently carried out surveys
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