DOCSLIB.ORG

Microbiologytoday Biology and Pathogenesis Current Technology and Author: Naveed Khan Molecular Biology Applications

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text

Load more

Caister Academic Press New Books for 2009 www.caister.com Acanthamoeba Lactobacillus Real-Time PCR microbiologytoday Biology and Pathogenesis Current Technology and Author: Naveed Khan Molecular Biology Applications ... available now! c. 220 pp., February 2009 From Genomics to Probiotics Edited by: J. Logan, K. Edwards and N. Saunders ISBN: 978-1-904455-43-1 $310 / £150 Edited by: Åsa Ljungh and Torkel Wadström x + 284 pp., January 2009 The first comprehensive review of c. 220 pp., January 2009 ISBN 978-1-904455-39-4 $310 / £150 Acanthamoeba research to be published. ISBN 978-1-904455-41-7 $310 / £150 A comprehensive guide to the latest PCR The current state of research on every aspect An essential reference for all dairy of this organism, detailing major advances platforms, fluorescent chemistries, validation technologists, microbiologists and in areas such as genomics, molecular and software, data analysis, internal and external cellular biology, life cycles, geographical biotechnologists. Includes phylogenetics, controls and a wide range of applications: distribution, role in ecosystem, morphology, taxonomy, comparative genomics, functional clinical diagnostics, biodefense, RNA vol35|nov08 genomics, the intestinal microflora, surface motility, phylogenetics, genotyping, metabolism, expression studies, validation of array data, quarterly regulation of morphogenesis, host-parasite proteins, stress responses, interaction with mutation detection, food authenticity and interactions, the molecular and immunological the immune system, probiotics, anti-cancer legislation, NASBA, and molecular halotyping. basis of pathogenesis, methods of transmission, potential, and much more. Essential reading for magazine of epidemiology, clinical manifestation, diagnosis, all scientists involved with lactic acid bacteria treatment, new target development and drug or probiotic research and a recommended book the society resistance. This book is the definitive guide to Clostridia ... available now! current research on this increasingly important for all microbiology laboratories. Molecular Biology in the Post- for general organism. ... available now! genomic Era Edited by: H. Brüggemann and G. Gottschalk microbiology Mycobacterium x + 230 pp., January 2009 Genomics and Molecular Biology ISBN 978-1-904455-38-7 $310 / £150 Bacterial Secreted Edited by: Tanya Parish and Amanda Brown The first coherent picture of the organism's viii + 214 pp., January 2009 molecular and cellular biology in this post- Proteins ISBN 978-1-904455-40-0 $310 / £150 genomic era. Include botulinum and tetanus Secretory Mechanisms and Role in Expert scientists critically review the current neurotoxins, C. difficile large exotoxins, C. Pathogenesis and most recent advances in the genomics and perfringens enterotoxin, pore-forming and Edited by: Karl Wooldridge molecular biology of mycobacteria. The focus binary bacterial toxins, molecular epidemiology, c. 550 pp., April 2009 is on the topical and most relevant aspects metabolic networks, genetic knock-out systems, ISBN: 978-1-904455-42-4 $310 / £150 and the authors aim to give readers an insight surface structures, anti tumor potential, and Extensive publication on bacterial secreted into the current understanding of the subject antibiotic resistance determinants. proteins, secretory systems and their vital role and the future direction of research. Topics in bacterial pathogenesis. Immense value covered include strain variation and evolution, to all microbiologists, molecular biologists, hypervirulent strains, electron transport and public health scientists and other researchers Plant Pathogenic respiration, lipid biosynthesis, DNA repair, and professionals engaged in the study ... available now! of pathogenesis, drug design and vaccine oxygen signaling, sulphur metabolism, protein Bacteria development. A skillful selection of topics and secretion, the protein kinase family, and Genomics and Molecular Biology a panel of acknowledged experts as authors much more. A valuable reference text for all Edited by: Robert W. Jackson have ensured that this volume will become an microbiology laboratories and essential reading xii + 330 pp., January 2009 important reference source for many years to for all scientists and researchers involved with ISBN 978-1-904455-37-0 $310 / £150 come. mycobacteria. An invaluable, up-to-date summary of the molecular biology and genomics of plant pathogenic bacteria. Includes: bacterial Other Books of Interest evolution, diversity and taxonomy, adaptation, Agrobacterium, Leifsonia, Pectobacterium, • Plasmids: Current Research and Future Trends Pseudomonas, Ralstonia, Xanthomonas, and • Pasteurellaceae: Biology, Genomics and Molecular Aspects Xylella, MAMPs and innate immunity, virulence • Vibrio cholerae: Genomics and Molecular Biology factors, regulation, plasmids and bioinformatics. • Pathogenic Fungi: Insights in Molecular Biology • Helicobacter pylori: Molecular Genetics and Cellular Biology ... available now! • Corynebacteria: Genomics and Molecular Biology FULL DETAILS AT Microbial • Staphylococcus: Molecular Genetics • Leishmania: After The Genome Production of • Archaea: New Models for Prokaryotic Biology WWW.CAISTER.COM • Legionella: Molecular Microbiology Biopolymers and • RNA and the Regulation of Gene Expression: A Hidden Layer of Complexity • Molecular Oral Microbiology Polymer Precursors • Epigenetics Applications and Perspectives • Animal Viruses: Molecular Biology Edited by: Bernd H. A. Rehm bugs on bugs • Segmented Double-Stranded RNA Viruses: Structure and Molecular Biology x + 294 pp., January 2009 microbial diseases of bees • Acinetobacter Molecular Biology ISBN 978-1-904455-36-3 $310 / £150 • Pseudomonas: Genomics and Molecular Biology Describes the most important biopolymers produced by microorganisms. Chapters provide fungal farmers of the insect world a molecular insight into biosynthesis pathways, wolbachia and gene transfer For more details or to order any of these books visit our website physical properties and industrial production www.caister.com processes. Includes metabolic engineering. shedding light on photorhabdus ORDER FROM (UK/Europe): Caister Academic Press, c/o Book Systems Plus, BSP House, Station Road, Linton, Cambs CB21 4NW, UK an inside job – bdellovibrio Tel: 01223 894870 Fax: 01223 894871 http://uk.caister.com ORDER FROM (USA): Caister Academic Press, c/o ISBS, Inc., 920 NE 58th Avenue, Suite 300, Portland OR 97213-3786, USA nature’s experiment – bacteriophages Tel: 503 287-3093 Fax: 503 280-8832 http://usa.caister.com contents vol35(4) regular features 159 News 202 Schoolzone 212 Hot off the Press 166 Microshorts 206 Gradline 215 Going Public 199 Conferences 209 Addresses 218 Reviews other items 196 National Subject Profiles 210 Obituary – Professor Chris Thurston articles 168 Microbial diseases of bees 184 An inside job: Bdellovibrio Travis Glare & Maureen O’Callaghan bacteriovorus Bees play an essential role in the world’s ecosystems, but Liz Sockett microbial diseases are posing a big threat to these vital These predatory bacteria hunt down and eat their fellow insects. organisms. 172 Ancient fungal farmers 188 Bacteriophages: nature’s most of the insect world successful experiment Garret Suen & Cameron Graham Hatfull Currie Phages could well be the world’s biggest reservoir of Leaf-cutter ants not only grow fungi to eat. They unidentified genetic material. weed their ‘gardens’ and apply pesticides too. 192 1983: a vintage year for 176 Bacterial sequences in an pathogen discovery invertebrate genome Robin Weiss Important findings about three major infectious Julie Dunning Hotopp & Jason Rasgon diseases were made 25 years ago. Some arthropods and nematodes need their bacterial inhabitants to survive. 220 Comment: 180 Photorhabdus: shedding light Scotoma in contemporary on symbioses microbiology Susan Joyce and David Clarke Howard Gest Which amazing microbe can make nematodes glow in the Are some bacteria really ‘unculturable’? Probably not dark and yet kill certain insects? according to this writer. Cover image Macrophotograph of the head of a worker honey bee (Apis mellifera). Dr Jeremy Burgess / Science Photo Library The views expressed Editor Dr Matt Hutchings––Editorial Board Dr Sue Assinder, Dr Paul Hoskisson, Professor Bert Rima––Managing Editor Janet Hurst––Assistant Editors Lucy Goodchild & Faye Stokes by contributors are not Editorial Assistant Yvonne Taylor––Design & Production Ian Atherton––Contributions are always welcome and should be addressed to the Editor c/o SGM HQ, Marlborough House, necessarily those of the Basingstoke Road, Spencers Wood, Reading RG7 1AG–Tel. 0118 988 1809–Fax 0118 988 5656–email [email protected]–web www.sgm.ac.uk Society; nor can the Advertising David Lancaster, Ten Alps Publishing, London Office, 10 Savoy Street, London WC2E 7HR–t 0207 878 2316–f 0207 379 7118–e [email protected] Regular feature images pp. 159 SGM; 203, 219 Comstock / Jupiter Images; 207, 213 Stockbyte; 209 Digital Vision / Getty claims of advertisers © 2008 The Society for General Microbiology––ISSN 1464-0570––Printed by Latimer Trend & Company Ltd, Plymouth, UK be guaranteed. Set your PhD on the right track with a New Student NEB Starter Pack news FREE New SGM Prize Medal Surveys on Open Access Journals to all new research Stanley B. Prusiner accepts award for 2009 I represent SGM on the Biosciences Federation (BSF) Journals SGM is pleased to announce that Dr Stanley B. Prusiner, Committee. We have recently carried out surveys
Recommended publications
  • Annual Conference Abstracts

    Annual Conference Abstracts

    ANNUAL CONFERENCE 14-17 April 2014 Arena and Convention Centre, Liverpool ABSTRACTS SGM ANNUAL CONFERENCE APRIL 2014 ABSTRACTS (LI00Mo1210) – SGM Prize Medal Lecture (LI00Tu1210) – Marjory Stephenson Climate Change, Oceans, and Infectious Disease Prize Lecture Dr. Rita R. Colwell Understanding the basis of antibiotic resistance University of Maryland, College Park, MD, USA as a platform for early drug discovery During the mid-1980s, satellite sensors were developed to monitor Laura JV Piddock land and oceans for purposes of understanding climate, weather, School of Immunity & Infection and Institute of Microbiology and and vegetation distribution and seasonal variations. Subsequently Infection, University of Birmingham, UK inter-relationships of the environment and infectious diseases Antibiotic resistant bacteria are one of the greatest threats to human were investigated, both qualitatively and quantitatively, with health. Resistance can be mediated by numerous mechanisms documentation of the seasonality of diseases, notably malaria including mutations conferring changes to the genes encoding the and cholera by epidemiologists. The new research revealed a very target proteins as well as RND efflux pumps, which confer innate close interaction of the environment and many other infectious multi-drug resistance (MDR) to bacteria. The production of efflux diseases. With satellite sensors, these relationships were pumps can be increased, usually due to mutations in regulatory quantified and comparatively analyzed. More recent studies of genes, and this confers resistance to antibiotics that are often used epidemic diseases have provided models, both retrospective and to treat infections by Gram negative bacteria. RND MDR efflux prospective, for understanding and predicting disease epidemics, systems not only confer antibiotic resistance, but altered expression notably vector borne diseases.
  • The Bdellovibrio Bacteriovorus Twin-Arginine Transport System Has Roles in Predatory and Prey-Independent Growth

    The Bdellovibrio Bacteriovorus Twin-Arginine Transport System Has Roles in Predatory and Prey-Independent Growth

    Microbiology (2011), 157, 3079–3093 DOI 10.1099/mic.0.052449-0 The Bdellovibrio bacteriovorus twin-arginine transport system has roles in predatory and prey-independent growth Chien-Yi Chang,1 Laura Hobley,1 Rob Till,1 Michael Capeness,1 Machi Kanna,23 William Burtt,1 Pratik Jagtap,34 Shin-Ichi Aizawa2 and R. Elizabeth Sockett1 Correspondence 1Institute of Genetics, School of Biology, University of Nottingham Medical School, R. Elizabeth Sockett Nottingham NG7 2UH, UK [email protected] 2Prefectural University of Hiroshima, 562 Nanatsuka, Shobara, Hiroshima 727-0023, Japan 3Max-Planck Institute for Developmental Biology, 72076 Tu¨bingen, Germany Bdellovibrio bacteriovorus grows in one of two ways: either (i) predatorily [in a host-dependent (HD) manner], when it invades the periplasm of another Gram-negative bacterium, exporting into the prey co-ordinated waves of soluble enzymes using the prey cell contents for growth; or (ii) in a host-independent (HI) manner, when it grows (slowly) axenically in rich media. Periplasmic invasion potentially exposes B. bacteriovorus to extremes of pH and exposes the need to scavenge electron donors from prey electron transport components by synthesis of metalloenzymes. The twin-arginine transport system (Tat) in other bacteria transports folded metalloenzymes and the B. bacteriovorus genome encodes 21 potential Tat-transported substrates and Tat transporter proteins TatA1, TatA2 and TatBC. GFP tagging of the Tat signal peptide from Bd1802, a high-potential iron–sulfur protein (HiPIP), revealed it to be exported into the prey bacterium during predatory growth. Mutagenesis showed that the B. bacteriovorus tatA2 and tatC gene products are essential for both HI and HD growth, despite the fact that they partially complement (in SDS resistance assays) the corresponding mutations in Escherichia coli where neither TatA nor TatC are essential for life.
  • 1471-2164-13-670.Pdf

    1471-2164-13-670.Pdf

    Hobley et al. BMC Genomics 2012, 13:670 http://www.biomedcentral.com/1471-2164/13/670 RESEARCH ARTICLE Open Access Genome analysis of a simultaneously predatory and prey-independent, novel Bdellovibrio bacteriovorus from the River Tiber, supports in silico predictions of both ancient and recent lateral gene transfer from diverse bacteria Laura Hobley1,3, Thomas R Lerner1,4, Laura E Williams2, Carey Lambert1, Rob Till1, David S Milner1, Sarah M Basford1, Michael J Capeness1, Andrew K Fenton1,5, Robert J Atterbury1,6, Maximilian ATS Harris1 and R Elizabeth Sockett1* Abstract Background: Evolution equipped Bdellovibrio bacteriovorus predatory bacteria to invade other bacteria, digesting and replicating, sealed within them thus preventing nutrient-sharing with organisms in the surrounding environment. Bdellovibrio were previously described as “obligate predators” because only by mutations, often in gene bd0108, are 1 in ~1x107 of predatory lab strains of Bdellovibrio converted to prey-independent growth. A previous genomic analysis of B. bacteriovorus strain HD100 suggested that predatory consumption of prey DNA by lytic enzymes made Bdellovibrio less likely than other bacteria to acquire DNA by lateral gene transfer (LGT). However the Doolittle and Pan groups predicted, in silico, both ancient and recent lateral gene transfer into the B. bacteriovorus HD100 genome. Results: To test these predictions, we isolated a predatory bacterium from the River Tiber- a good potential source of LGT as it is rich in diverse bacteria and organic pollutants- by enrichment culturing with E. coli prey cells. The isolate was identified as B. bacteriovorus and named as strain Tiberius. Unusually, this Tiberius strain showed simultaneous prey-independent growth on organic nutrients and predatory growth on live prey.
  • Holding Hands with Bacteria the Life and Work of Marjory Stephenson

    Holding Hands with Bacteria the Life and Work of Marjory Stephenson

    SPRINGER BRIEFS IN MOLECULAR SCIENCE HISTORY OF CHEMISTRY Soňa Štrbáňová Holding Hands with Bacteria The Life and Work of Marjory Stephenson 123 SpringerBriefs in Molecular Science History of Chemistry Series editor Seth C. Rasmussen, Fargo, North Dakota, USA More information about this series at http://www.springer.com/series/10127 Soňa Štrbáňová Holding Hands with Bacteria The Life and Work of Marjory Stephenson 1 3 Soňa Štrbáňová Academy of Sciences of the Czech Republic Prague Czech Republic ISSN 2191-5407 ISSN 2191-5415 (electronic) SpringerBriefs in Molecular Science ISSN 2212-991X SpringerBriefs in History of Chemistry ISBN 978-3-662-49734-0 ISBN 978-3-662-49736-4 (eBook) DOI 10.1007/978-3-662-49736-4 Library of Congress Control Number: 2016934952 © The Author(s) 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication.
  • Microbiology Society Activities

    Microbiology Society Activities

    MICROBIOLOGY TODAY 48:1 May 2021 Microbiology Today 48:1 May 2021 Life on a Changing Planet Life on a Changing Planet Exploring the relationship between climate change and the microbial world Forest Fire in Dixie National Forest, Utah, USA. santirf/iStock which in turn increase the risk of COVID-19 complications. impact on respiratory health of affected communities. Curr Opin Pulm Wildfire smoke exposure might also increase the likelihood of Med 2019;25:179–187. comorbidities, including cardiovascular diseases, respiratory Wu X, Nethery RC, Sabath MB, Braun D, Dominici F. Air pollution and diseases, diabetes and hypertension, leading to an increased COVID-19 mortality in the United States: strengths and limitations of an ecological regression analysis. Sci Adv 2020;6:eabd4049. COVID-19 risk. Higher daily average PM2.5 concentrations during the wildfire season in western US states were positively Gosling SN, Bryce EK, Dixon PG, Gabriel KMA, Gosling EY et al. associated with increased influenza rates the following A glossary for biometeorology. Int J Biometeorol 2014;58:277–308. winter, indicating strong evidence for delayed effects of wildfire exposure. Research on understanding the underlying mechanisms between wildfire exposure and respiratory Rosa von Borries infection is an area of active investigation. Consultant at World Meteorological Organization, In particular, vulnerable population groups such as socio- Bernhard-Lichtenberg-Str 15, 10407 Berlin, economically disadvantaged populations, individuals with Germany comorbidities and the elderly face higher risks of experiencing [email protected] the combined consequences of COVID-19 and wildfires. @rosavborries In the US, migrant farmworkers who were continuously linkedin.com/in/rosa-von-borries-5b4987197 exposed to wildfire smoke and deemed essential workers during the pandemic faced much higher risks of severe Rosa von Borries holds an MSc in Public Health from London School health consequences from wildfire smoke and COVID-19.
  • An Inside Job: Bdellovibrio Bacteriovorus Some Predatory ‘Bugs’ Eat Other ‘Bugs’ from Inside, As Liz Sockett and Her Research Group Have Found

    An Inside Job: Bdellovibrio Bacteriovorus Some Predatory ‘Bugs’ Eat Other ‘Bugs’ from Inside, As Liz Sockett and Her Research Group Have Found

    An inside job: Bdellovibrio bacteriovorus Some predatory ‘bugs’ eat other ‘bugs’ from inside, as Liz Sockett and her research group have found. dellovibrio are small (0.25× Bdellovibrio where the acquisition of a large number of genes periplasmic growth phase, during which they reside inside the 1.0 µm), flagellate, motile, for hydrolytic enzymes, and for penetrating and resealing dead prey cell, degrading it by secreting enzymes across the Gram-negative deltapro- the prey cell, give access to an intracellular niche, bounded prey cytoplasmic membrane to digest prey macromolecules, teobacteria which invade by the prey-cell outer membrane, where the Bdellovibrio can and taking up the products for Bdellovibrio growth. Bdellovibrio and kill other Gram-nega- ‘dine privately’ on the inner contents of the prey cell without seem to be mostly ‘locked on’ to predatory growth in dilute tive bacteria, entering the competition for nutrients from other bacteria. This contrasts environments and cannot productively switch to HI growth to Bprey cell’s periplasm, replicating within with the ‘eating habits’ of other deltaproteobacteria such survive, but depend on finding prey for replication. During the it and using the contents of that as the myxobacteria which digest prey externally and take free-swimming attack phase, rapid prey location, attachment bacterium as their nutrient source. up digested prey nutrients partly in competition with other and recognition are vital to the successful replication of the Bdellovibrio bacteriovorus HD100 is the bacteria in their surroundings. Bdellovibrio, as they typically have a half-life of about 10 sequenced strain and has a 3.8 Mb gen- hours during starvation in buffered environments.
  • Qumrter{Y Rn{-}#R.}Rin* Nf Thw S**:Imty Rnicrr:Hl*I*E5r

    Qumrter{Y Rn{-}#R.}Rin* Nf Thw S**:Imty Rnicrr:Hl*I*E5r

    F r-nierobiologytodcly i W; vol33i oug06 ,: qumrter{y rn{-}#r.}rin*nf thw s**:imty f'*r 6*[":*l"C*l rnicrr:hl*i*E5r I f vcl33(3) [*j'l-l l.-ili:i i" t'.ir'iliL.i i{:}li 90 News 128 Cradline 134 Reviews 122 Meetings 130 Hotoff the press 139 Addresses 124 Schoolzone132 Coingpublic it'l i:)'i-:il;I i i i::ji-i-l:; 117 Usingmicroscopy to enhanceundergraduate teaching 127 Letter 136 obituaries i:l l'Tl{,-li:}S 96 Fluorescencemicroscopy Canyou seethe asa researchtool in bacterial light? cellbiology lain Hagan , AgnesCrallert & Jeff Errington SteveBagley The revolution of new views of the subcellularorganization Simpleand affordable steps to exploitrecent of bacteria. advancesin ffuorescenceimaging. 100 |nvestigating a bacterial killer usingatomic force microscopy 118 HenryBaker: author of the MeganNufiez & EileenSpain first m icroscopy labo ratory Learnabout the secretlife of the predatorykiller, Bdellovibrio. manual Virusesand intracellular RichardBurns This18th century polymath played a big partin popularizing movement earlymicroscopes. TomWileman How do virusesmanaSe to move within and between the cellsof their host? Comment - Openoption for SCM 108 Studyingsingle molecules in journals microbialsystems RonFraser & RobinDunford ChristophBaumann Openaccess demands by grant-awardingbodies Individualmolecules in livingcells can now be observed. arecausing problems for publishers. {ovr:r inoge Microscopelenses. Tony Craddock / SciencePhoto Library Theviews expressed fditr.rrDrCavinThomas[lcii|*riili{l*"lrdDr5ueAssinder'Professor|ainHagan,ProfessorBertRlma
  • 70Th Anniversary Collection of the Microbiology Society: Journal of General Virology Robin A

    70Th Anniversary Collection of the Microbiology Society: Journal of General Virology Robin A

    Journal of General Virology (2015), 00, 1–3 DOI 10.1099/jgv.0.000286 Commentary 70th Anniversary Collection of the Microbiology Society: Journal of General Virology Robin A. Weiss Correspondence Division of Infection & Immunity, University College London, London WC1E 6BT, UK Robin A. Weiss [email protected] To mark the 70th anniversary of the founding of the Society From its inception, the Journal of General Virology took for General Microbiology (now renamed the Microbiology papers on the structure and design of virus particles, Society) it was decided to showcase 70 salient publications such as human adenovirus type 5. In a superb biochemical from the archives of its various journals. The Journal of Gen- and structural analysis comprising three consecutive eral Virology was allocated 15 papers. I was invited to curate papers, the second paper by Russell et al. (1967) showed them and given a carte blanche which ones to choose. True that when heated to 56 8C, the icosahedral capsid ruptured to the name of the journal, I picked a broad range of viruses at the penton bases and liberated viral DNA. They also cor- and a paper on prion disease. If readers are disappointed not rectly predicted that unknown nucleocore proteins exist to see their own most cherished contribution featured that in later years became important for understanding among them, please consider the odds: only 15 from over cell transformation and early steps in virus replication. 15 000 Journal of General Virology articles could be selected The only paper among the 15 selected that does not present and I gave more weight to older papers to recall contri- primary research data is the commentary on virus diversity butions by the pioneers of virology.
  • Microbiology@UCL Virtual Symposium 2020

    Microbiology@UCL Virtual Symposium 2020

    Microbiology@UCL Virtual Symposium 2020 Day 1: 28th July 9:00 – 12:30 08:50 – 09:00 Welcome and housekeeping (opening slides) 09:00 Opening: Joanne Santini (Structural & Molecular Biology and Domain lead) Session 1 (Chair: Snezana Djordjevic, Structural & Molecular Biology) 09:05 Keynote: Rotem Sorek (Weizmann Institute of Science) The immune system of bacteria: Beyond CRISPR 09:35 Mark Marsh (MRC Laboratory for Molecular Cell Biology) Membrane trafficking plays an essential role in lentiviral pathogenesis 09:50 George Blundell-Hunter (Pharmaceutics) Characterisation of bacteriophage-encoded depolymerases selective for key Klebsiella pneumoniae capsular exopolysaccharides 09:55 Georgina Benn (London Centre for Nanotechnology and Institute of Structural & Molecular Biology) Imaging the surface of live bacteria with nanometre resolution 10:00 Samuel Ellis (Infection, Immunity & Inflammation, GOSH Institute of Child Health) Impact of binding respiratory syncytial virus G protein on pneumococcal cell division and antibiotic sensitivity 10:05 Poster Session 1 (Chair: China Hanson, Microbiology@UCL Domain Manager) 10:30 Jason Mercer (MRC Laboratory for Molecular Cell Biology) Seeing is believing: Super-resolving poxvirus protein architecture 10:45 15min break Session 2 (Chair: TBA) 11:00 Jürg Bähler (Genetics, Evolution & Environment) Natural variant of pyruvate kinase in fission yeast tunes energy metabolism and triggers systems-wide adaptations in cellular regulation and physiology 11:15 Gabriel Tarrason Risa (MRC Laboratory for Molecular
  • Downloaded from the SGM Website

    Downloaded from the SGM Website

    F I: t' SGMHeadquarterc MarlborouqhHouse. Articles Basingsto[eRoad, Spencers Thingsthat go rotin the night - Wood,Reading RG7 lAG Tel.01 18 988 1800 a reviewof biodeteriorationGlyn Morton 103 Fax01 189885656 [email protected] Everythingyou wanted to knowaboutthe dry-rot SGMWebsite fungusbutwere afraid to askJohnW Palfreyman http:./www.sgm.ac.uk &NiaA.White 107 Editor Lichens,agents of monumentaldestruction DrMerielJones MarkR.D.Seaward 110 EditorialBoard ProfessorDave Kelly Conservationof monu m ental stones bv bacterial ProfessorTonyNash biomineralizationBrunetla Perito &Giorgio Mastromei 1 13 ManagingEditor JanetHurst Sulfate-red uci n g bacteriain biofiI ms on metalIic Production Editor materialsand corrosion lwonaB. Beech 11 5 lanAtherton AssistantEditorand TheBiodeterioration Centre, University of Herbfordshire BookReviewManager RichardSmith 1 18 JaniceMeekings Pilzkrieg :the German warti me quest for penicil lin Gontributions Theseare always welcome and GilbertShama 120 shouldbe addressed tothe Editor AcuteRespi ratory rome(SARS) (c/o SGM Headquarters), Severe Synd FaveJones 124 CopyDates Lastdates for receipt of copy atMarlborouqh House are aeneratuopv Regular Featunes November2003 issue 1 Sept Februarv2004 issue 8 December MicroShorts 117&141 AOVerUSemen$ (LKl-.l November2003 issue 29 Sept SocietyNews February2004 issue1 9 January MayCouncilMeeting 126 Advertisements Above:Ascanning usuallycaused bysulfate- NewsofMembers 126 (SRB) Allenquiriesshould be sentto: electronmicrograph of the reducingbacteria and StaffNews 126 Domin
  • Microbiologytoday

    Microbiologytoday

    microbiologytoday microbiology vol36|feb09 quarterly magazine of the society today for general microbiology vol 36 | feb 09 the legacy of fleming ‘that’s funny!’: the discovery of penicillin what manner of man was fleming? the future of antibiotic discovery look who’s talking when good bugs fight bad contents vol36(1) regular features 2 News 38 Schoolzone 46 Hot off the Press 10 Microshorts 42 Gradline 49 Going Public 36 Conferences 45 Addresses 60 Reviews other items 33 The Defra-commissioned independent review of bovine tuberculosis research 54 Education Development Fund report 58 Obituary – Professor Sir James Baddiley FRS 59 Obituary – Emeritus Professor Naomi Datta FRS articles 12 ‘That’s funny!’: the 24 Look who’s talking! discovery and development Julian Davies of penicillin Antibiotics aren’t just for fighting infections; they are part of the bacterial signalling network. Kevin Brown The chance discovery of penicillin 80 years ago made Alexander Fleming a famous scientist. 28 When good bugs fight bad Roy Sleator 16 What manner of man was There are alternative methods available Alexander Fleming? for combating infectious diseases – not just antimicrobial chemotherapy. Philip Mortimer Alexander Fleming, the Society’s first President, did so much more than discover penicillin. 32 A precious memory Norberto Palleroni One of the few people left who met Fleming recounts his 20 Antibiotics and experience. Streptomyces: the future of antibiotic discovery 64 Comment: Debating creationism Flavia Marinelli Many options for drug discovery
  • Microbiology Society

    Microbiology Society

    MICROBIOLOGY TODAY 47:1 May 2020 Microbiology Today May 2020 47:1 Why Microbiology Matters – 75th anniversary issue Why Microbiology Matters We are celebrating our 75th anniversary by showcasing why microbiology matters and the impact of microbiologists past, present and future. MICROBIOLOGY TODAY 47:1 May 2020 Microbiology Today May 2020 47:1 Why Microbiology Matters – 75th anniversary issue Why Microbiology Matters We are celebrating our 75th anniversary by showcasing why microbiology matters and the impact of microbiologists past, present and future. Editorial Welcome to Microbiology Today, which has a new look. This issue is the first of two special editions of the magazine to be published in the 75th anniversary year of the Microbiology Society. As we look back and celebrate during 2020, we are also considering ‘Why Microbiology Matters’. The longer you think about it, the more you realise how in so many ways it does. Whole Picture ince the first observations of microbes by Antonie van thrive in extreme conditions and are found in every niche Leeuwenhoek in the 1600s, our understanding of how around the globe. Smicrobes underpin and impact our lives has advanced Part of the reason for the success of microbes in these considerably. From discovering their life cycles and roles within varied environments is their genetic plasticity. Charles Dorman various environmental niches to harnessing them in industrial introduces the next section on microbial genetics and the role processes, and, not least, our ability to utilise them for good, to it has played in advancing modern biotechnology. From the vaccinate and treat diseases, with many diseases now known original discovery of restriction enzymes through to potential to be caused by microbes.