GENETIC CALCULATOR (HORSE COLOUR) Help File
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I . the Color Gene C
THE ABC OF COLOR INHERITANCE IN HORSES W. E. CASTLE Division of Genetics, University of California, Berkeley, California Received October, 27, 1947 HE study of color inheritance in horses was begun in the early days of Tgenetics. Indeed many facts concerning it had already been established earlier, by DARWINin his book on “Variation of Animals and Plants under Domestication.” At irregular inteivals since then, new attempts have been made to collect and classify in terms of genetic factors the records contained in stud books concerning the colors of colts in relation to the colors of their sires and dams. A full bibliography is given by CREWand BuCHANAN-SMITH (19301. By such studies, we have acquired very full information as to what color a colt may be expected to have, when the color of its parents and grandparents is known. This knowledge is empirical rather than experimental in nature. For horses being slow breeding and expensive are rarely available for direct experi- mental study, such as can be made with the small laboratory mammals, mice, rats, rabbits and guinea pigs. We have definite information that color inheritance in horses involves the existence of mutant genes similar to those demonstrated by experimental studies to be involved in color inheritance of other mammals. But the horse genes have been given special names, as they were successively discovered, and it is difficult at present to correlate them with the better known names and geneic symbols used by the experimental breeders. The present paper is an attempt to make such a correlation. Just as in morphological studies comparative anatomy was found useful and still is used to establish homologies between systems of organs, so in mammalian genetics, a comparative study of gene action in the production of coat colors and color patterns may also be of value. -
Use of Genomic Tools to Discover the Cause of Champagne Dilution Coat Color in Horses and to Map the Genetic Cause of Extreme Lordosis in American Saddlebred Horses
University of Kentucky UKnowledge Theses and Dissertations--Veterinary Science Veterinary Science 2014 USE OF GENOMIC TOOLS TO DISCOVER THE CAUSE OF CHAMPAGNE DILUTION COAT COLOR IN HORSES AND TO MAP THE GENETIC CAUSE OF EXTREME LORDOSIS IN AMERICAN SADDLEBRED HORSES Deborah G. Cook University of Kentucky, [email protected] Right click to open a feedback form in a new tab to let us know how this document benefits ou.y Recommended Citation Cook, Deborah G., "USE OF GENOMIC TOOLS TO DISCOVER THE CAUSE OF CHAMPAGNE DILUTION COAT COLOR IN HORSES AND TO MAP THE GENETIC CAUSE OF EXTREME LORDOSIS IN AMERICAN SADDLEBRED HORSES" (2014). Theses and Dissertations--Veterinary Science. 15. https://uknowledge.uky.edu/gluck_etds/15 This Doctoral Dissertation is brought to you for free and open access by the Veterinary Science at UKnowledge. It has been accepted for inclusion in Theses and Dissertations--Veterinary Science by an authorized administrator of UKnowledge. For more information, please contact [email protected]. STUDENT AGREEMENT: I represent that my thesis or dissertation and abstract are my original work. Proper attribution has been given to all outside sources. I understand that I am solely responsible for obtaining any needed copyright permissions. I have obtained needed written permission statement(s) from the owner(s) of each third-party copyrighted matter to be included in my work, allowing electronic distribution (if such use is not permitted by the fair use doctrine) which will be submitted to UKnowledge as Additional File. I hereby grant to The University of Kentucky and its agents the irrevocable, non-exclusive, and royalty-free license to archive and make accessible my work in whole or in part in all forms of media, now or hereafter known. -
Official Standard of the French Bulldog General Appearance
Official Standard of the French Bulldog General Appearance: The French Bulldog has the appearance of an active, intelligent, muscular dog of heavy bone, smooth coat, compactly built, and of medium or small structure. Expression alert, curious, and interested. Any alteration other than removal of dewclaws is considered mutilation and is a disqualification. Proportion and Symmetry - All points are well distributed and bear good relation one to the other; no feature being in such prominence from either excess or lack of quality that the animal appears poorly proportioned. Influence of Sex - In comparing specimens of different sex, due allowance is to be made in favor of bitches, which do not bear the characteristics of the breed to the same marked degree as do the dogs. Size, Proportion, Substance: Weight not to exceed 28 pounds; over 28 pounds is a disqualification. Proportion - Distance from withers to ground in good relation to distance from withers to onset of tail, so that animal appears compact, well balanced and in good proportion. Substance - Muscular, heavy bone. Head: Head large and square. Eyes dark in color, wide apart, set low down in the skull, as far from the ears as possible, round in form, of moderate size, neither sunken nor bulging. In lighter colored dogs, lighter colored eyes are acceptable. No haw and no white of the eye showing when looking forward. Ears Known as the bat ear, broad at the base, elongated, with round top, set high on the head but not too close together, and carried erect with the orifice to the front. The leather of the ear fine and soft. -
Identification of Horses Booklet
colours & marking booklet_10366 21/7/08 14:32 Page 1 1 Introduction The first edition of this booklet was made available to the veterinary profession in 1930. It was in the form of a report from a Sub-Committee, which had been set up by the Council of the RCVS in 1928, to prepare a system of description, colours and markings, etc. of horses for the purpose of identifying individual animals. Since that date there have been several revised editions. Amendments have been made in the light of experience and in response to the changing demands of the equine industry. The significant increase in the international movement of horses and the insistence by a growing number of organisations which hold shows, gymkhanas, events and other competitive functions that horse owners should supply proof of vaccination against equine influenza, have resulted in greater numbers of practitioners being asked to supply the relevant certification. Additionally DEFRA legislation came into force in 2004 requiring all horses to have a passport containing an accurate set of markings. This latest edition (published May 2008) has been produced by Weatherbys, in conjunction with the RCVS and BEVA, in part as a result of the increased use internationally of microchip transponders to identify horses. Nevertheless, the passport, with its recording of a horse’s colour and markings, remains the essential means of identification for Thoroughbred and Non-Thoroughbred horses and ponies under the implementation Regulation of the EC Directives (Commission Regulation (EC) No. 504/2008 of 6 June 2008 and Council Directives 90/426/EEC and 90/427 EEC. -
Special Issue Horse Genetics DIRECTOR’S Message
CENTER FOR EQUINE HEALTH SCHOOL OF VETERINARY MEDICINE • UNIVERSITY OF CALIFORNIA, DAVIS SUMMER 2020 Special Issue Horse Genetics DIRECTOR’S Message s an equine genetics researcher, I am particularly excited to share A this special issue of the Horse Report with you. Inside, you will find a roadmap to many of the currently available equine genetic tests, including the AQHA “five-panel” test, and more. The equine genome sequence was published in 2009, the result of a years- long collaborative effort by the international equine research community. This resource drastically changed how researchers approach equine genetics and accelerated the rate of discovery. Increased availability and affordability allowed the application of advanced molecular tools to equine diseases and traits. As a result, genetic tests are available in a variety of breeds. Most available tests are for simple, Mendelian diseases and traits – those caused by a single gene or locus. Complex diseases and traits likely involve more than one gene and may be influenced by environmental effects. The 2018 release of a new equine genome sequence assembly, coupled with cost reductions that make whole-genome sequencing possible for large numbers of horses, are enabling research in these areas. As an equine geneticist and veterinarian, I am especially interested in applying whole genome sequencing and advanced diagnostic tools to equine precision medicine. This highly individualized approach will focus on early detection and prevention of disease, taking into account both genetic information and environmental factors. The idea is to target individuals based on their clinical condition as well as their unique body chemistry and genetics. -
Cob Or Chimera?
Cob or Chimera? UK Expat Sarah Redstone Lee explains why she believes the Cob Normand to be the most versatile cob of them all nce we had decided to take the The origins of the Normandy Cob can be To this day, the Chateau of Versailles is still plunge, sell up, pack up and traced back to Great Britain, the first ‘Norman’ surrounded by carriage driving Normandy make the move to Normandy; horse, to arrive on our shores was during the Cobs in homage to his passion for the breed. code named Operation transportation of a herd of around 2- 3,000, in The National Stud and home of the Overseas ( as but a small preparations for the battle of Hastings of 1066. Normandy Cob was founded by Napoléon in homage to operation Overlord in Normandy, Much of the success of the invasion depended 1806. By 1840, some of the cobs were crossed Owhich formed part of the D-Day landings), it on the horses that were bred for the endurance with King Henry the VIII’s favourite breed, was not long before my husband and I were required in order to carry the weight of the now extinct Norfolk trotter. This further enjoying la belle vie Francaise. We have been armoured suits, weapons and chain mail, yet the enhanced the look of elegance combined here for almost 10 years now, and, aside from superior among them also possessed great speed. with speed. The standard was set and the benefitting from the usual attractions that The Normans, are even to this day well Normandy Cob was then divided in to two France has to offer, that needs no form of known for their breeding of the Percheron groups; heavier horses for work, and lighter introduction, I have been very privileged to and the French Trotter. -
The Occurrence of Silver Dilution in Horse Coat Colours
ISSN 1392-2130. VETERINARIJA IR ZOOTECHNIKA (Vet Med Zoot). T. 60 (82). 2012 THE OCCURRENCE OF SILVER DILUTION IN HORSE COAT COLOURS Erkki Sild, Sirje Värv and Haldja Viinalass Institute of Veterinary Medicine and Animal Sciences, Estonian University of Life Sciences Kreutzwaldi 1, 51014 Tartu, Estonia; Tel: +372 731 3469; Fax: +372 742 2344; e-mail: [email protected] Abstract. The MC1R allele “e” in the homozygous state leads to the production of pheomelanin and is responsible for inhibition of expression of the silver dilution gene (PMEL17 “Z” allele). Horse coat colour is one of the traits breeders select for. A total of 133 horses representing Estonian Native (48), Estonian Heavy Draught (40) and Tori (45) breeds were genotyped for key polymorphisms at C901T in MC1R, the 11 bp deletion in ASIP and C1457T in PMEL17 to determine horse coat colour variation and selection possibilities to increase silver-diluted colours. Our genotyping results showed the “ee” genotype frequency in the MC1R gene to be as follows: Estonian Native 45.8%, Estonian Heavy Draught 65.0%, and Tori 77.8%, and the “Z_” genotype in PMEL17 to be 10.4%, 12.5%, and 0.0%, respectively. Six of total 133 horses with silver dilution were examined for MCOA. No eye abnormalities were detected. Considering the PMEL17 gene singly, silver coat colour could be expressed phenotypically in 12% of genotyped Estonian Heavy Draught horses, but due to unfavourable covariation with the MC1R “e” allele, it only occurred in two per cent of horses. Keywords: ASIP, horse coat colour, MC1R, MCOA, PMEL17, silver phenotype. -
19/07/2018 Page 1 of 9 Genetic Screening Tests Available Symbol
Genetic Screening Tests available Symbol Name Description of variant effects Genetic Disease Testing CA is a neurological disorder that affects the cells in the cerebellum, causing head tremors, ataxia and other effects. Affected horses are more likely to fall and are generally not safe to ride. Symptoms appear from 6 weeks to around 4 months old. CA has been linked to a mutation in the TOE1 Cerebellar CA gene and is a recessive disorder, meaning that a horse must Abiotrophy be homozygous (CA/CA) to be affected. If a horse is a carrier (CA/n), it will not show any clinical signs of CA, but it will pass the variant on to approximately half its offspring. Mating to other carriers should be avoided to prevent the birth of an affected foal. LFS causes neurological dysfunction in foals. The symptoms include seizures, hyperextension of the limbs, neck and back, leg paddling, and inability to stand. As the name suggests, LFS also dilutes to the coat to a pale lavender pink or silver colour. The foal will not improve and will die, so it should be euthanised. LFS is a recessive disorder so two copies of the Lavender Foal defective version of the MYO5A gene must be inherited LFS Syndrome (LFS/LFS) for a foal to be affected. If a horse is a carrier (LFS/n), it will not show any clinical signs of LFS. However, there is a 50% chance it will pass the variant to its offspring, so mating to other carriers should be avoided to prevent the birth of an affected foal. -
The Show of Colours
THE SHOW OF COLOURS Celebration of every horse SHOWING CLASSES FOR ALL colour – classes for all WITH EVENING PERFORMANCE SPECTACULAR Sunday 7th July 2019 CLASSES FOR ALL HORSES AND PONIES COLOURED, TWO TONE AND SOLID £13.00 Pre entry £15.00 entry on the day Fun classes £10.00 – pre entry and on the day EVENING PERFORMANCE INCLUDING COLOUR PARADE, CLASS AND COLOUR CHAMPIONSHIPS QUALIFYING SHOW FOR CHAPS (UK) OPPORTUNITY TO GAIN POINTS FOR THE HOWE GRAND FINALE AND STEP TOWARDS THE CHANCE TO WIN £500 FOR YOURSELF AND £500 FOR YOU CHOSEN CHARITY QUALIFYING SHOW FOR OUR NEW ECOSSE ELITE TROPHY FOR SCOTTISH BREEDS THE CHANCE TO WIN £100 FOR YOURSELF AND £100 FOR YOU CHOSEN CHARITY QUALIFYING SHOW FOR THE CALEDONIAN SHOWING CHAMPIONSHIPS Please be aware that “Not Before Times” are only as a guide, classes will not start before these times but may start considerably later depending on entries Pre enter on Equo Pre entries close on 3rd July 2019 THE SHOW OF COLOURS – SUNDAY 7th JULY 2019 Welcome to the schedule of the Show of Colours which run in four rings; Ring 1 - Coloured Ring – for all Skewbald and Piebald Ring 2 -Two Tone Ring – for all Roan, Palomino, Spotted and Dun/Buckskin Ring 3 - Solid Ring – for all Black, Grey, Chestnut and Bay Ring 4 - Fun Ring - for all colours Ring 5 - TGCA Scottish Regional Show - The day of showing classes for all horses and ponies of all breeds and types will culminate in an Evening Performance Spectacular. EVENING PERFORMANCE (not before 4.30pm) CONCOURS DE ELEGANCE COLOUR PARADE Free entry – open to all please take part in hand or ridden, details on next page. -
Horse Coat Color Test Results Dt34839
HORSE COAT COLOR TEST RESULTS TONI PERDEW Case: DT34839 3005 LEXINGTON CT Date Received: 05-Aug-2013 BEDFORD, IA 50833 Report Date: 07-Aug-2013 Report ID: 3263-6964-9709-4059 Verify report at https://www.vgl.ucdavis.edu/myvgl/verify.html Horse: HI JACD SILVER Reg: 5220615 DOB: 05/31/2009 Breed: QH Sex:M Alt. ID: Sire: MAINLY MERLIN Reg: Dam: BAILEYS BADLAND BUCK Reg: W10 DOMINANT RED FACTOR Not requested. Not requested. WHITE SPLASHED AGOUTI Not requested. Not requested. WHITE CREAM Not requested. TOBIANO Not requested. PEARL Not requested. LEOPARD Not requested. SILVER Not requested. GRAY Not requested. Horse is homozygous for the Dun gene. All DUN ROAN Not requested. D/D offspring should be dun dilute. CHAMPAGNE Not requested. LETHAL WHITE Not requested. OVERO SABINO 1 Not requested. For more details on horse coat color tests, please visit: www.vgl.ucdavis.edu/services/coatcolorhorse.php Tests for Gray, Leopard/Appalossa and Lethal White Overo are performed under license. Horse Coat Color Results with Explanations Red Factor Silver e/e - Only the red factor detected. Basic color is sorrel or chestnut in the absence of other N/N - No evidence of the altered sequence detected. modifying genes. N/Z - One copy of the altered sequence detected. Black-based horses will be chocolate with flaxen E/e - Both black and red factors detected. Either E or e transmitted to offspring. Basic color is or lightened mane and tail. Bay-based horses will have lightened black pigment on lower legs, mane black, bay or brown in the absence of other modifying genes. -
Homozygous Tobiano and Homozygous Black Could Be Winners for Your Breeding Program, If You Know How to Play Your Cards
By IRENE STAMATELAKYS Homozygous tobiano and homozygous black could be winners for your breeding program, if you know how to play your cards. L L I T S K C O T S N N A Y S E T R U O C n poker, a pair is not much to brag gets one of the pair from the sire and the in equine color genetics. If your goal about. Two pairs are just a hair bet - other of the pair from the dam.” is a black foal, and you’ve drawn the ter. But in equine color genetics, a Every gene has an address—a spe - Agouti allele, you’re out of luck. pair—or, even better, two—could cific site on a specific chromosome. be one of the best hands you’ll ever We call this address a locus—plural The Agouti effect hold. We’re talking about a sure bet— being loci. Quite often, geneticists use Approximately 20 percent of horses a pair of tobiano or black genes. the locus name to refer to a gene. registered with the APHA are bay. If Any Paint breeder will tell you that When a gene comes in different you also include the colors derived producing a quality foal that will forms, those variations are called alle - from bay—buckskin, dun, bay roan bring in top dollar is a gamble. In this les. For example, there is a tobiano and perlino—almost one-quarter of business, there are no guarantees. But allele and a non-tobiano allele. Either registered Paints carry and express the what if you could reduce some of the one can occur at the tobiano locus, Agouti allele, symbolized by an upper - risk in your breeding program as well but each chromosome can only carry case A. -
Gene C Profile Test Results
GeneGc Profile Test Results Horse: ByeMe Champagne Owner: Wendall, Jane Horse and Owner Informaon Horse ByeMe Champagne DOB 6/1/2007 Breed Paint Age 7 Color Classic Champagne Sex S Discipline Western Height 14.2 Registry APHA Reg. Number 12345 Sire Bye Bye Baby Dam Super Champagne Sire Reg. 9058-234 Dam Reg. 4314-334 Comments: Excellent Temperament Owner Wendall, Jane Address Tinseltown Phone 555-1212 City Hollywood, CA E-mail [email protected] Zip Code 91604 GeneGc Profile Test Results Horse: ByeMe Champagne Owner: Wendall, Jane Results Summary Coat Color : ByeMe Champagne has one Black allele and one Red allele making the Base coat appear Black. Also detected were single Champagne and Cream alleles; likely resulUng in a rare Champagne Cream color. One copy of the Frame Overo allele is also detected, indicang underlying white patches (hidden By CH). As a result of single gene copies in each of the following, he has a 50% chance of passing Black or Red, Cream and/or Champagne, AgouU and/or Frame Overo alleles to his offspring. Allele Summary: Aa, Ee, Ch, Cr, LWO/n Traits: ByeMe Champagne is a not a carrier of any known recessive disease genes. CauUon is recommended however, as any mare Bred to him should Be Frame Overo negave as to avoid a 25% chance of foal death (+/+ LWO results in a lethal condiUon at Birth). He may also throw Gaited foals when Bred to Gaited (+) mares. Notes: Please note that your analysis is ongoing and may include some regions marked with an asterisk denoUng the following: * Discovery – This gene detecUon is in the