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( https://doi.org/10.1017/S0029665116000288 121 ) oee,teefcso statins of effects the However, . . IPaddress: fl ec h icda system circadian the uence fi ayadtoxicity and cacy 170.106.33.19 , on icda euaino iis447 lipids of regulation Circadian fl 30 Sep2021 at14:00:25 – uences activ- ( 124 ) – . h uhrwssll epnil o l set fprep- of paper. aspects this all of for responsible aration solely was author The None. under Singapore, (SHF), Foundation SHF/FG410P/2009. Research and SingHealth Medical NMRC/NIG/1000/2009; the National under the Singapore Science, Council, Singapore; Ministry for the Health, and Agency of Singapore, the Signature Research, Duke-NUS and by Technology, the funded by Program supported Research was work This paper. this carrying in Sleep for described School and experiments Medical Chronobiology out Duke-NUS the at in Laboratory researchers thank We circadian- on obesity metabolism of lipid and for impact risk disorders. eating, and metabolism the night lipid regulated delineate work, to shift lipi- approaches that of expect experimental amplitude can we and pro studies, domics future timing In the rhythms. lipid in substantial are differences there but individual plasma, in oscillations circadian .Bro M unF aa 20)Phototransduc- (2002) M Takao & FA Dunn DM, Berson 7. .Ymzk ,Kreha C okrCG Hocker MC, Kerbeshian S, Yamazaki 6. .Bh D&TkhsiJ 21)Mlclrcmoet of components Molecular (2013) JS Takahashi & ED lipid Buhr of 5. regulation Diurnal (2014) EC Chua & JJ Gooley 4. .ZriprA hi ad 21)diyetn pat- eating daily (2016) S Panda & A Chaix A, Zarrinpar 3. .Abeh 21)Tmn opreto:tebooyo cen- of biology the perfection: to Timing (2012) U Albrecht 2. .Cese A&Goe J(07 le n circadian and Sleep (2007) JJ Gooley & CA Czeisler 1. , subjectto theCambridgeCore termsofuse,available at inb eia aginclsta e h icda clock. circadian the set that cells ganglion Science retinal by tion htmcpoete ftehmtrspahamtcnu- suprachiasmatic hamster the cleus of properties Rhythmic h amla icda clock. 217 circadian lipidomics. Mammalian the circadian of Genomic applications Genet J and metabolism en n hi mato elhaddisease. and health on impact Metab their Endocrinol and terns rladprpea icda clocks. circadian peripheral and tral 72 humans. in rhythms 579 , ,3 nvivo in – 27. – 295 fi 597. igwl eue ncmiainwt other with combination in used be will ling 1070 , . Neurosci J Con Acknowledgements iaca Support Financial – 41 27 1073. 231 , fl ,69 Authorship References odSrn abSm un Biol Quant Symp Harb Spring Cold cso Interest of icts – 18 – 83. 250. 10709 , – ad x Pharmacol Exp Handb 10723. Neuron 74 tal et 246 , (1998) . Trends – 260. https://www.cambridge.org/core/terms Downloaded from Proceedings of the Nutrition Society 448 9 uJ hn H huTC Chou YH, Zhang J, Lu 19. 7 otra E asekA aFerSE Fleur la A, Kalsbeek JE, Oosterman 27. dorsome- The (2006) CB Saper & A Schomer JJ, Gooley 18. JJ Gooley TE, Scammell TC, Chou 17. 6 aaaiS uaoR b M Abe R, Numano S, Yamazaki 16. 5 aaaY uoaH at K Saito H, Kuroda Y, Tahara 25. 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