Description Cy5 LG Cy3 MI Ratio(Cy3/Cy5) C9orf135
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Supplementary Table S2. DNA microarray dataset of top 30 differentially expressed genes and housekeeping genes Up-regulated in SI cancer cells Symbol Description Cy5_LG Cy3_MI Ratio(Cy3/Cy5) C9orf135 Uncharacterized protein C9orf135 1.37 307.8 224.3 KIAA1245 Notch homolog 2 N-terminal like protein 1.82 406.8 223.6 APITD1 Centromere protein S (CENP-S) 2.56 560.3 218.7 PPIL6 Peptidyl-prolyl cis-trans isomerase-like 6 1.85 343.0 185.7 MYCBP2 Probable E3 ubiquitin-protein ligase MYCBP2 2.01 332.1 165.6 ANGPTL4 Angiopoietin-related protein 4 precursor 10.26 1500.1 146.3 C10orf79 Novel protein (Fragment) 2.86 415.5 145.5 NP_653323.1 KPL2 protein isoform 2 1.82 257.5 141.6 ZNF345 Zinc finger protein 345 1.58 215.7 136.8 SIX1 Homeobox protein SIX1 1.59 216.1 136.0 KLHL7 Kelch-like protein 7 1.91 254.4 133.3 TBX1 T-box transcription factor TBX1 1.57 209.0 133.1 PAG1 Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 2.19 290.9 133.0 NOL12 Nucleolar protein 12 1.61 203.7 126.5 ZNF606 Zinc finger protein 606 2.12 267.7 126.0 NFKBIE NF-kappa-B inhibitor epsilon 5.28 658.3 124.7 ZMYND10 Zinc finger MYND domain-containing protein 10 6.85 835.5 121.9 hCG_23177 - 14.94 1758.9 117.7 KIF3A Kinesin-like protein KIF3A 1.94 224.9 116.1 Q9C0K3_HUMAN Actin-related protein Arp11 3.38 368.0 108.9 NP_056263.1 DPCD protein 2.61 270.5 103.7 GBP1 Interferon-induced guanylate-binding protein 1 1.46 149.1 102.3 NP_660151.2 NAD(P) dependent steroid dehydrogenase-like 1.35 137.4 101.5 NP_689672.2 CDNA FLJ90761 fis, clone THYRO1000099 3.68 372.5 101.2 CLIC6 Chloride intracellular channel 6 3.80 384.1 101.0 EFEMP1 EGF-containing fibulin-like extracellular matrix protein 1 precursor 3.81 384.1 100.8 Q9H5T8_HUMAN CDNA: FLJ23049 fis, clone LNG02559 1.90 180.5 94.8 PPP2R2B Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform 1.59 150.3 94.4 IL21 Interleukin-21 precursor 5.74 539.3 94.0 Q8N7G4_HUMAN coiled-coil domain containing 65 1.82 170.8 93.7 Down-regulated in SI cancer cells Symbol Description Cy5_LG Cy3_MI Ratio(Cy3/Cy5) Q9BT26_HUMAN MGC10981 protein 1120.25 5.81 0.0052 TFF2 Trefoil factor 2 precursor 26891.88 211.67 0.0079 RPUSD2 RNA pseudouridylate synthase domain containing protein 2 476.84 7.47 0.0157 ZNF403 Protein ZNF403 364.27 5.97 0.0164 TRIM7 Tripartite motif-containing protein 7 298.72 5.43 0.0182 ZBTB43 Zinc finger and BTB domain-containing protein 43 444.88 8.61 0.0193 TNNT2 Troponin T, cardiac muscle (TnTc) 380.65 7.68 0.0202 PLCG2 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 310.55 6.87 0.0221 DUS3L tRNA-dihydrouridine synthase 3-like 294.05 7.20 0.0245 IMPA1 Inositol monophosphatase 395.55 9.80 0.0248 RBPMS RNA-binding protein with multiple splicing 524.22 13.88 0.0265 CCDC28A Coiled-coil domain-containing protein 28A 275.84 7.56 0.0274 ERCC3 TFIIH basal transcription factor complex helicase XPB subunit 190.63 5.47 0.0287 TMEM9 Transmembrane protein 9 precursor 348.56 10.08 0.0289 LEFTY1 Left-right determination factor B precursor 1773.60 53.48 0.0302 MAP3K5 Mitogen-activated protein kinase kinase kinase 5 477.70 14.45 0.0302 AKR1A1 Alcohol dehydrogenase [NADP+] 702.30 21.34 0.0304 MUC5AC Mucin-5B precursor 58659.88 1800.84 0.0307 TUBB2A Tubulin beta-2A chain 2448.33 75.78 0.0310 FBP2 Fructose-1,6-bisphosphatase isozyme 2 430.55 14.21 0.0330 SDSL Serine dehydratase-like 381.19 12.63 0.0331 NOLA3 H/ACA ribonucleoprotein complex subunit 3 187.52 6.44 0.0343 JMJD2A JmjC domain-containing histone demethylation protein 3A 590.51 20.62 0.0349 MDM4 Mdm4 protein 186.93 6.83 0.0366 C20orf20 MRG-binding protein 152.65 5.59 0.0367 CHAF1A Chromatin assembly factor 1 subunit A 344.47 12.90 0.0375 COQ6 Ubiquinone biosynthesis monooxygenase COQ6 198.67 7.82 0.0393 UCKL1 Uridine/cytidine kinase-like 1 441.44 17.43 0.0395 POLR3D DNA-directed RNA polymerase III subunit D 191.83 7.62 0.0397 NRG4 Pro-neuregulin-4, membrane-bound isoform 203.67 8.13 0.0399 Housekeeping genes Symbol Description Cy5_LG Cy3_MI Ratio(Cy3/Cy5) ATP5F1 ATP synthase B chain, mitochondrial precursor 361.45 732.68 2.0 RPLP0 60S acidic ribosomal protein P0 961.93 1797.41 1.9 RPLP1 60S acidic ribosomal protein P1 20859.88 19989.68 1.0 RPLP2 60S acidic ribosomal protein P2 7688.30 13304.57 1.7 RPS18 40S ribosomal protein S18 11225.88 14512.14 1.3 PPIA Peptidyl-prolyl cis-trans isomerase A 3077.17 3042.43 1.0 TBP TATA-box-binding protein 49.61 46.24 0.9 ACTB Actin, cytoplasmic 1 (Beta-actin). 4756.86 7476.08 1.6 B2M Beta-2-microglobulin precursor 18517.88 23095.28 1.2 GUSB Beta-glucuronidase precursor 45.67 57.89 1.3.