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Magnesium Sulfate | Memorial Sloan Kettering Cancer Center PATIENT & CAREGIVER EDUCATION Magnesium Sulfate This information from Lexicomp® explains what you need to know about this medication, including what it’s used for, how to take it, its side effects, and when to call your healthcare provider. Brand Names: US Epsom Salt [OTC]; GoodSense Epsom Salt [OTC]; M2 Magnesium [OTC]; Magnacaps [OTC] [DSC] What is this drug used for? Injection: It is used to treat or prevent low magnesium levels. It is used to prevent and control seizures during pregnancy. Granules used by mouth: It is used to treat constipation. Granules used as soaks: It is used to treat minor sprains or bruises. All products: It may be given to you for other reasons. Talk with the doctor. Magnesium Sulfate 1/8 What do I need to tell my doctor BEFORE I take this drug? All products: If you are allergic to this drug; any part of this drug; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had. Injection: If you have heart block. If you have heart problems. If you are taking any of these drugs: Nifedipine or terbutaline. Granules used by mouth: If you have any of these health problems: Bowel block, belly pain, upset stomach, rectal bleeding, throwing up, or change in bowel habits lasting longer than 2 weeks. This is not a list of all drugs or health problems that interact with this drug. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this drug with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor. What are some things I need to know or do while I take this drug? All products: Tell all of your health care providers that you take this drug. This includes your doctors, nurses, pharmacists, and dentists. If you are on a low-magnesium diet, talk with your doctor. Tell your doctor if you are pregnant, plan on getting pregnant, or are breast- Magnesium Sulfate 2/8 feeding. You will need to talk about the benefits and risks to you and the baby. Injection: Have blood work checked as you have been told by the doctor. Talk with the doctor. This drug may contain aluminum. There is a chance of aluminum toxicity if you are on this drug for a long time. The risk is greater if you have kidney problems. The risk is also higher in premature infants. Talk with the doctor. Do not take if you have myasthenia gravis. Very bad and sometimes deadly breathing problems have happened with this drug in people who have myasthenia gravis. Granules used by mouth: Try to space other drugs from this one by 2 hours. This drug stops many drugs from getting into the body. Do not use this drug for more than 1 week unless told to do so by your doctor. If you have rectal bleeding or you do not have a bowel movement after using this drug, talk with your doctor. Talk with the doctor before you give this drug to a child younger than 6 years old. What are some side effects that I need to call my doctor about right away? WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: All products: Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; Magnesium Sulfate 3/8 trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. Injection: Signs of high magnesium levels like confusion, feeling sluggish, slow movements, shortness of breath, upset stomach, or very bad dizziness or passing out. Signs of low calcium levels like muscle cramps or spasms, numbness and tingling, or seizures. Slow heartbeat. Flushing. Not able to move. Change in eyesight. Feeling cold. Sweating a lot. Call your doctor right away if you have new or worse muscle weakness, trouble chewing or swallowing, trouble breathing, droopy eyelids, or change in eyesight like blurred eyesight or seeing double. These could be signs of a life- threatening muscle problem. Granules used by mouth: Very upset stomach or throwing up. Black, tarry, or bloody stools. Cramps. What are some other side effects of this drug? All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Magnesium Sulfate 4/8 Granules used by mouth: Diarrhea. Upset stomach or throwing up. These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects. You may report side effects to your national health agency. You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch. How is this drug best taken? Use this drug as ordered by your doctor. Read all information given to you. Follow all instructions closely. Injection: It is given as a shot into a muscle or as an infusion into a vein over a period of time. Granules used by mouth: Mix in 8 ounces (240 mL) of water. Lemon juice may be added to make it taste better. Take with a full glass of water. Granules used as soaks: Mix with water as you have been told before using this drug. Soak for as long as you were told by your doctor, then pat dry. Magnesium Sulfate 5/8 What do I do if I miss a dose? Granules: This drug is used on an as needed basis. Do not use more often than told by the doctor. Injection: Call your doctor to find out what to do. How do I store and/or throw out this drug? Granules: Store at room temperature in a dry place. Do not store in a bathroom. Injection: If you need to store this drug at home, talk with your doctor, nurse, or pharmacist about how to store it. All products: Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets. Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area. General drug facts If your symptoms or health problems do not get better or if they become worse, call your doctor. Do not share your drugs with others and do not take anyone else’s drugs. Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, nurse, pharmacist, or Magnesium Sulfate 6/8 other health care provider. Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about this drug, please talk with your doctor, nurse, pharmacist, or other health care provider. If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened. Consumer Information Use and Disclaimer This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine. The use of this information is governed by the Lexicomp End User License Agreement, available at https://www.wolterskluwer.com/en/solutions/lexicomp/about/eula. Last Reviewed Date 2021-03-22 Copyright © 2021 UpToDate, Inc. and its affiliates and/or licensors. All rights reserved. Magnesium Sulfate 7/8 If you have any questions, contact a member of your healthcare team directly. If you're a patient at MSK and you need to reach a provider after 5:00 PM, during the weekend, or on a holiday, call 212-639-2000. For more resources, visit www.mskcc.org/pe to search our virtual library. Magnesium Sulfate - Last updated on August 31, 2021 All rights owned and reserved by Memorial Sloan Kettering Cancer Center Magnesium Sulfate 8/8.
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