CURRICULUM VITAE DAVID J. TOLLERUD, M.D., M.P.H.

Address

Department of Environmental and Occupational Health Sciences School of Public Health and Information Sciences University of Louisville 485 East Gray Street, Suite 205-A Louisville, KY 40202 Phone (502) 852-3007 / Fax (502) 852-3291 [email protected]

Education

1990 MPH Harvard School of Public Health, Epidemiology 1978 MD Mayo Medical School, Medicine 1972 BS Stanford University, Mechanical Engineering University of Minnesota, Pre-Medical Course work

Postgraduate Training

1978-1979 Yale-New Haven Medical Center, Intern, Internal Medicine 1979-1981 Beth Israel Hospital, Resident, Internal Medicine 1981-1982 Beth Israel Hospital, Chief Resident, Internal Medicine 1982-1985 NIH National Cancer Institute, Medical Staff Fellow, Environmental Epidemiology 1985-1986 Brigham and Women’s Hospital, Clinical Fellow in Medicine, Pulmonary Medicine 1985-1986 Beth Israel Hospital, Clinical Fellow in Medicine, Pulmonary Medicine 1988-1990 Brigham and Women’s Hospital, Research/Clinical Fellow, Epidemiology

Employment History

1979-1981 Harvard Medical School, Clinical Fellow in Medicine 1981-1982 Harvard Medical School, Instructor in Medicine 1985-1986 Harvard Medical School, Clinical Fellow in Medicine 1986-1988 University of Cincinnati, School of Medicine Assistant Professor of Clinical Medicine, Pulmonary Disease 1988-1990 Harvard Medical School, Instructor in Medicine 1990-1992 University of Pittsburgh, Graduate School of Public Health Assistant Professor, Dept. of Environmental and Occupational Health (EOH) 1990-1996 University of Pittsburgh School of Medicine Assistant Professor, Pulmonary and Critical Care Medicine 1991-1992 University of Pittsburgh, Graduate School of Public Health Interim Director, Division of Occ. and Environmental Medicine, Dept. of EOH 1992-1996 University of Pittsburgh, Graduate School of Public Health Associate Professor, Dept. of EOH 1992-1996 Chief, Division of Occupational and Environmental Medicine University of Pittsburgh, Graduate School of Public Health Associate Chairman, Department of EOH 1996-2003 MCP Hahnemann University, School of Public Health, Professor of Public Health Director, Center for Environmental and Occupational Health 1996-Present University of Pittsburgh, Graduate School of Public Health Adjunct Professor of Environmental and Occupational Health 1997-1998 Allegheny University of the Health Sciences, Philadelphia, PA Director of Population Studies, Institute for Cellular Therapeutics

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1997-1998 Allegheny Univ. of the Health Sciences, Center for Violence and Injury Control Associate Director, Philadelphia Campus 1998-Present University of Louisville, School of Medicine, Louisville, KY, Professor of Medicine Associate Director, Institute for Cellular Therapeutics 2002-Present University of Louisville, School of Public Health and Information Sciences Professor of Public Health and Pharmacology/Toxicology 2002-2003 University of Louisville, School of Public Health and Information Sciences Acting Chair, Department of Environmental and Occupational Health Sciences 2003-Present University of Louisville, School of Public Health and Information Sciences Chair, Department of Environmental and Occupational Health Sciences 2005-2006 University of Louisville, School of Public Health and Information Sciences Associate Director, Masters of Public Health Program 2008-Present University of Louisville, School of Medicine, Associate in Department of Pharmacology/Toxicology

Licensure (Active)

1999-present Medicine Kentucky

Certification

1981 American Board of Internal Medicine (ABIM) 1986 ABIM Subspecialty of Pulmonary Disease 1989 ABIM Subspecialty of Critical Care Medicine 1991 American Board of Preventive Medicine (ABPM: Occupational Medicine)

Membership in Professional Societies

American College of Occupational and Environmental Medicine (ACOEM) American College of Physicians (ACP) American Conference of Governmental Industrial Hygienists (ACGIH) American Industrial Hygiene Association (AIHA) American Public Health Association (APHA) American Society of Hematology (ASH) American Society of Public Health (ASPH) American Society of Transplantation (AST) American Thoracic Society (ATS) European Respiratory Society (ERS) Kentucky Public Health Association (KPHA) The Transplantation Society

Honors and Awards

1972 Tau Beta Pi, Honorary Engineering Society 1985 Scholarship Award, American College of Chest Physicians 1992 Delta Omega, Honorary Society in Public Health 1993 Fellow, American College of Occupational and Environmental Medicine 1997 Fellow, American College of Preventive Medicine 1995 Fellow - American College of Preventive Medicine 1998 Golden Apple Teaching Award 2001 National Associate, National Academies of Science 2004/2008 Distinguished University Scholar Award, University of Louisville (renewed 2008)

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Educational Activities

1. Medical Education (1978-1990)

Courses, lectures, and seminars were given to medical students, residents and fellows during my tenure as a Medical Resident (1979-1981), Chief Resident (1981-1982), Pulmonary Fellow (1985-1986) and as a Faculty Member in Pulmonary and Critical Care Medicine (1986-1990), covering general medical topics as well as pulmonary, critical care, and environmental epidemiology subject matter.

Medical Grand Rounds: Grand rounds presentation on “Nocturnal Asthma” to the Medical staff, residents and medical students at St. Raphael’s Hospital in New Haven, Connecticut, a teaching hospital affiliated with Yale University School of Medicine, in January, 1981.

Pulmonary Medicine Grand Rounds: Seminar Presentation on “Immunological Effects of Cigarette Smoking” to the faculty, residents and fellows of the Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Pittsburgh School of Medicine, October 1990.

Postgraduate Seminar: Lecture on “Environmental Influences on the Immune System” given as part of a postgraduate seminar on Multiple Chemical Sensitivity given at the American College of Occupational Medicine State-of-the-Art Conference, October 1990.

Invited Speaker: “Current Trends in the Treatment of Obstructive Lung Disease,” given at the Annual Meeting of the Massachusetts Society for Respiratory Care, October 1990.

Postgraduate Course: “Medical Surveillance”, American Academy of Industrial Hygiene 1991 Annual Congress, Pittsburgh, PA, September 1991.

Invited Speaker: “Repetitive Motion Disorders” at the Tri-state Occupational Medicine Association Annual Meeting, Pittsburgh, PA, September 1991.

Invited Speaker: “School for Excellence for Health Care Professions” at the PA Governor’s School held at the University of Pittsburgh, July 1993-95.

Medical Grand Rounds: Grand rounds presentation on “TB, the Forgotten Plague” to the medical staff and residents at the Washington Hospital, Washington, PA, October 1995 Invited participant: “USPHS Workshop on Laboratory and Epidemiologic Approach to Determining the Role of Environmental Exposures as Risk Factors for B-Cell Chronic Lymphocytic Leukemia and other B cell Lymphoproliferative Disorders”, held by the Center for Disease Control, Atlanta, GA, June 1995.

Co-sponsor: EPOCH/Environmental Conference, November 1995.

Invited Speaker: “Biological Aspects of Cytokines of Indoor Air Quality:, Drexel University, Philadelphia, PA, May 7, 1998.

2. Graduate School - University of Pittsburgh (1990-1996)

Industrial Environmental Health Sciences: Organized and directed a 3-credit overview course (EOH 2001) for occupational medicine residents and graduate students in allied disciplines.

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Industrial Ergonomics: Organized and taught a 3-credit course in ergonomics (EOH 2063) for occupational medicine residents and graduate students in environmental and occupational health.

Occupational and Environmental Health: Organized and directed a new 3-credit core course for the occupational medicine residency program (EOH 2005). This course will also be available for Continuing Medical Education (CME) credits for occupational medicine practitioners and other health professionals wishing to increase their knowledge about environmental and occupational health.

Health, Disease and Environment: Taught segments on occupational diseases, noise hazards and heat stress, and accidental injury in the workplace in an introductory course for graduate students in the Graduate School of Public Health.

Immunotoxicology: Assisted in an Immunotoxicology course taken by all occupational medicine residents. Topics focus on state of the art immunological concept and their application to occupational and environmental health.

Journal Club: Organized and directed an Occupational Medicine Journal Club for residents in occupational medicine and students and faculty in related disciplines.

Organ Systems Toxicology: Taught segment on Toxicology of the Hematopoietic and Immune Systems.

Repetitive Motion Disorders: Lecture presentation on Cumulative Trauma Syndrome and Repetitive Motion Disorders to the Dean’s Staff of the Graduate School of Public Health, University of Pittsburgh, March 1995.

Presented: “Serum Cytokines in Population Studies of Respiratory Disease” at Environmental and Occupational Health Department Seminar, April 1996.

Presented a review of the Institute of Medicine’s study on Agent Orange to the Risk Science Course, June, 1996.

Student Advising - University of Pittsburgh

Research (Thesis) Advisor Michael Baxley, M.D PGY3 - 9/89 - 8/91 Jay Harper, M.D. PGY3 - 9/90 - 9/92 Sean Muldoon, M.D. PGY3 - 9/90 - 8/92 Angelo Costantino, M.D. PGY3 - 7/91 - 6/93 Theresa Silvaggio, M.D. PGY3 - 9/90 - 8/92 Michael Kuniak, D.O. PGY3 - 8/93 - 7/95 Charles Cortinovitis, M.D. PGY3 - 8/94 - 7/96 Thomas Stone, M.D. PGY3 - 8/95 - 7/97 Mark Farley, J.D. Thesis 6/92 Thomas Campbell, M.D. Thesis 4/94 Toshihiko Satoh, M.D. PGY3 -1/94 Masashi Tsunoda, M.D. PGY3 - 8/93 - 12/94 Clarke T. Miller, M.D. Thesis 3/96

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Master’s Thesis Committees George Bondar, D.O. 8/92 Douglas Adams, M.D. 6/93 Angelo Costantino, M.D. 6/93 William Scorby, M.D. 7/94 Theodore Sofish, M.D. 7/94 Milton H. Black, M.D. 3/92 Edward J. Meros, M.D. 7/95 Thomas Campbell, M.D. 4/94 Fabienne Ransom, D.O. 7/95 Thomas Stone, M.D. 7/96 Rex T. Yang, M.D. 7/96 Janet Halliday 8/96

Doctoral Dissertation Committee Barbara Massuti 1994 Wei Chen 1995

3. Medical School - University of Pittsburgh (1990-1996)

Course Segment Director: “Introduction of Occupational and Environmental Medicine” to First Year Medical Students: - a 2-day course for incoming medical students, August 1992, 1993, 1994, 1995, and 1996.

Course Segment Director: “Occupational Lung Disease” - 2- segments of Epidemiology course taught to medical students, January 1993, 1994, 1995, and 1996.

Course Segment Director: “Ambulatory Care Class” - 1-day per month for first year medical students, Spring 1994, 1995, 1996 and Fall 1993, 1994, 1995, and 1996.

4. School of Public Health, MCP Hahnemann University / Allegheny University of the Health Sciences / Drexel University (1996-2002)

1996-2002 Small Group Facilitator and Block Leader, MPH Curriculum, Epidemiology and EOH Fall, Winter 1996, 1997, 1998, 2001, 2002. Winter 1999, 2000

1998-2002 Lectures, MD/MPH Program, Epidemiology and EOH Winter 1999, 2000, 2001, 2002

1998-2002 Lectures, Sch of Medicine, Asthma Epidemiology, Infectious Disease Epidemiology Fall 1999, 2000, 2001, 2002

Student Advising - MCP Hahnemann Univ Allegheny Univ of Health Sciences, Drexel Univ

Masters of Public Health Advisor Gary Fishbein Rajeswari Jeganathan Patt Panzer, MD Ann Ferraro Sherri Jurgens Uzma Rana Huong Nghiem Flavius Lilly Ericka Stroup Jonathan Cass Farhia Mussa Darius Wolman Dulcine Dinsmore Chau Nguyen Zavan Ghezelashouri Harold Ofori

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Masters of Public Health (EOH Major Discipline) Advisor Doua Xiong Kimberly Pruszko Nisha Bala Monica Reed Amena Husain MyongSin Yi Paula Maurrain Palak Raval-Nelson

Masters Thesis Committee Doua Xiong (Chair) Michael Srulevich Nisha Bala Kimberly Pruszko Dulcine Dinsmore Uzma Rana Amena Husain Darius Wolman Sherri Jurgens Myongsin Yi Flavius Lilly Ericka Stroup Paula Murrain James Yee Chau Nguyen

Ph.D. Advisor Thomas Armstrong Flavius Lilly

5. Medical School - University of Louisville

2000-2001 Lectures in Graduate Course: Introduction to Environmental Health Sciences, Fall 2000 and Fall 2001 2001 Lecture on Outcomes Research in IPHR Public Health Graduate Course 2008- Lectures on Environmental Health Sciences to Pharmacology/Toxicology

6. School of Public Health and Information Sciences, University of Louisville

2003- Development and teaching courses for MPH - Environmental and Occupational Health Concentration, and on-line for Kentucky’s Virtual University 2005- Development and teaching courses for PhD in Public Health - Environmental Health Concentration

Student Advising, University of Louisville Ph.D. Advisor Dissertation Committee Theresa Perry Robert LaRosa Therese Hughes, RN M. Caroline Chan, MPH Ashlee Melendez Natasha DeJarnett, MPH Maria Del Mar Cirino-Marcano, MD Sadiatu Musah Simin Khodadadi, MPH Ray Yeager, MPH

MPH Advisor Cassie Shipp Nikita Tailor Robert Loeb Rita Ann Jung Yu-ting Chen Thomas Boeshart Simin Khodadadi Cindy Elston Angela Perez Thomas Murro Erica Gunnison Natalie Moore Nancy Reinhardt Kaitlin Vollet Tina Brown Ciara Warren Ray Yeager

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Student Awards During Mentorship • Therese Hughes – Recipient of the “Dean’s Award for outstanding and exemplary performance and contributions by a graduating student” from the School of Public Health and “Outstanding Student Award” from the University of Louisville Graduate School, May 2007. • Nancy Reinhardt – Recipient of the “Dean’s Award for outstanding and exemplary performance and contributions by a graduating student” from the School of Public Health and “Graduate Dean’s Citation and “Outstanding Student Award” from the University of Louisville, May 2008 • Caroline Chan – Recipient of the “Dean’s Award for outstanding and exemplary performance and contributions by a graduating student” from the School of Public Health and “Graduate Dean’s Citation and “Outstanding Student Award” from the University of Louisville Graduate School, May 2007 & 2012 • Cindy Elston - Recipient of the “Dean’s Award for outstanding and exemplary performance and contributions by a graduating student” from the School of Public Health and “Graduate Dean’s Citation” from the University of Louisville Graduate School, May 2013. • Natasha DeJarnett - Recipient of the “Dean’s Award for outstanding and exemplary performance and contributions by a graduating student” from the School of Public Health and “Graduate Dean’s Citation” from the University of Louisville Graduate School, May 2013. • Sadiatu Musah – Recipient of University of Louisville Outstanding Student, Dec 2013

Health Care and Public Health Education of the Lay Community 1990 Lecture presentation to St Francis Hospital Health Assistance Program on “Repetitive Motion Disorders” 1992 Lecture presentation to Carnegie Mellon University Library Staff on “Repetitive Motion Disorders” 1992-1996 Annual presentation to G.E. Glass Plant Employees on “Safety to Prevent Lead Poisoning” 1993 Presentation to Pittsburgh Wellness Group on Ergonomics on “Wellness” 1993-1995 Invited speaker to Western PA Safety Council on “Blood Borne Pathogens” 1994 Presentation, Duquesne Light Company “Radiation Safety” seminar 1994-1995 Presentations at Western PA Safety Council conferences on “Protecting Health Care Workers from Tuberculosis” 1995 Presentation sponsored by Allegheny Medicare and Allegheny County Medical Society Occupational and Environmental Medicine Committee Presentation to Duquesne Light Company symposium on “The Threat of TB in Health Care Facilities” Presentation to Kennametal management and laborers on “Cobalt/Tungsten Carbide” Presentation to PA State Nursing Association on “Guidelines for Preventing the Transmission of Mycobacterium tuberculosis in Health Care Facilities 1996 Presentation to Bayer Corporation Health & Safety Retreat on “OSHA TB Standard” Invited Guest: “Medical Frontiers” Radio Broadcast on WWDB 96.5. Topic of Discussion: “What is New in Environmental and Community Health?” Presentation to outpatient physicians at Harmarville Rehabilitation Ctr, Pittsburgh, PA Presentation to Community College of Allegheny County (CCAC) on lead. Presentation to Pennsylvania Self-Insurer’s Association, “Managing Medical Care During the First 30 Days”

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Invited Speaker: Business Executives Advisory Panel, Occupational Health, Department of the University of Pittsburgh, Beaver Valley 1997 Invited speaker: “Assessing Cancer Risks”, one day course: “Environmental Medicine: Tools for Your Practice”, Department of Public Safety, Bureau of Health, City of Chester in collaboration with Chester City Board of Health: Crozer-Chester Medical Center, Department of Family Medicine, Allegheny University of the Health Sciences and the Agency for Toxic Substance Disease Registry (ATSDR), CDC, Philadelphia, PA 1997 Invited Speaker: “Lead Exposures in the Glass Industry”, a two day course: “Management of Environmental Lead Hazards: A Community Challenge” sponsored in part by the US EPA, Commonwealth of Pennsylvania, and the states of Ohio and West Virginia. The regional environmental conference organized through the Allegheny County Health Department Invited speaker to Western PA Safety Council Conference on “Lead - Dangers Invited Guest: “Medical Frontiers” Radio Broadcast on WWDB 96.5. Topic of discussion: “What is New in the Public Health Arena?” Leader and Speaker of Breakout session: Injury and Violence: Psycho/Social Stresses. Topic presented: “Potential Links Between Violence and Other Health Problems” at AUHS 1997 Research Conference, Valley Forge, PA, October. 2002 Invited Speaker: “Agent Orange: Medicine, Science and Policy,” Medical Grand Rounds, University of Louisville, Louisville, KY Invited Speaker: “The Development and Implementation of a Case-based Approach to Address Bioterrorism: An Educational Strategy,” Association of Schools of Public Health, Pittsburgh, PA Invited Speaker: “Policy Issues and the IOM Committee Process,” Board on Health Promotion and Disease Prevention, Institute of Medicine, and National Academies of Science. 2003 Television Program: Louisville Health discussing environmental issues Panel Member: Louisville Forum (Public Television and Public Radio) Television Program: Environmental Issues,” Insight Television, Louisville, KY 2004 Invited speaker: “KI Distribution Strategies in the Event of a Radiological Incident,” CDC, March 2005 Invited speaker: NRC Committee report on “Superfund Site Assessment and Remediation in the Coeur d’Alene River Basin,” EPA, presentations to congress and public, Washington, DC and Coeur d’Alene, OD, July. Invited Speaker: “Overview of Emerging Environmental Health Issues Affecting Women and Children’s Health: What Health Care Professionals Should Know,” Louisville, KY, October. Invited Speaker: “Childhood Asthma.” Jefferson County Public Schools, Louisville, KY, November. 2006 Invited Speaker: “Health.” Tenth Annual Race and Relations Conference, Louisville, KY, January. 2006 Invited Speaker: “Health.” Tenth Annual Race and Relations Conference, Louisville, KY, January. Invited Speaker: “Intellectual Approach to the Problems of Megasites.” Academy of Medicine Annual Superfund Basic Research Meeting, New York, NY, January. Invited Speaker: RHAC Report Release and Briefings to Congressional staff, Veterans Affairs and AFHS for National Academies of Science, Institute of Medicine, Washington, DC, February. Invited Speaker: University of Washington, Seattle, WA, April. Invited Moderator/Speaker: “Last Child in the Woods,” Louisville Metro Parks Advisor Board, Louisville, KY, November. Invited Speaker: Internal Medicine Update, Norton Health Care, Louisville, KY, December.

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2007 Invited Speaker: “Emerging Environmental Health Issues Affecting Women and Children’s Health: Metal Toxicity – Arsenic, Lead and Mercury. What Health Care Professionals Should Know - Local Issues.” UofL continuing education seminar, Louisville, KY, August 2008 Invited Moderator: “Climate Change,” University of Louisville, School of Public Health and Information Sciences, Louisville, KY, April Invited Speaker: “Environmental Health,” American Lung Association’s 2008 Pulmonary Care Symposium, Louisville, KY, May Invited Speaker: “Environmental Health: Exposures and Respiratory Issues,” Southern Kentucky Area Health Education Center (AHEC) Annual Conference, Mt. Vernon, KY, June 2009 Invited Moderator: “Health Care Transition Forum for Obama-Biden Transition Project,” University of Louisville, Louisville, KY, January Moderator: Center for Environmental Genomics and Integrative Biology, “Translational Biomarkers Workshop,” University of Louisville, Louisville, KY, February Invited Speaker: Zhejiang Academy of Medical Sciences, “Superfund Site Assessment and Remediation in the Coeur d’Alene River Basin,” Zhejiang, China, April Invited Speaker: School of Medicine Grand Rounds, “Pulmonary-Toxicology Lung Disease,” University of Louisville, Louisville, KY, June Invited Speaker: University Health Care Board of Director's Mtg, “National Children’s Study,” University of Louisville, Louisville, KY, June Invited Speaker: Department of Pediatrics Grand Rounds, “National Children’s Study,” Norton’s Hospital, Louisville, KY, September 2010 National Academy of Sciences, Institute of Medicine Workshop (Reviewer, panelist/consultant): A Workshop to Obtain Input on the Gulf Long-term Follow-up of Clean-up Workers Study, Tampa, FL, September Invited Speaker: Kentucky Environmental Foundation, Environmental Health Website/Call-in Series, August 2010 Invited Speaker: “National Children’s Study-Jefferson County, KY Center”, School of Public Health Research Incubation, August Invited Speaker: “Paducah Gaseous Diffusion Plant Study Results,” Workers and Community meetings, Paducah, KY, September 2011 Media interviews with WHAS-TV, WDRB-TV, WGTK-AM (Joe Elliott Show) and the Courier- Journal regarding the radiation exposure as it relates to the nuclear situation in Japan, March 2011 Presbyterian Union: “Nuclear Power and Radiation Risks – an Environmental Health Perspective, June Senate and House Committee on Veterans Affairs briefings on report of the Committee on Long- Term Health Consequences of Exposure to Burn Pits in Iraq and Afghanistan – Washington, DC, October Media interviews with Wall street Journal, USA Today, Wired.com, Pittsburgh Tribune-Review, WSJ.com, ABC-TV, November 2013 Research Incubation Meeting, School of Public Health & Information Sciences, University of Louisville, "Clinical Trials using the Facilitating Cell Technology - the Holy Grail of Transplantation", January Grand Rounds, University of Louisville, School of Medicine, “FCRx From Bench to Bedside”, September

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Professional Committees

1. Intramural - University of Pittsburgh

1990-1991 Ad Hoc School-wide Recruitment Committee (GSPH) 1990-1992 School-Wide MPH Committee (GSPH) 1990-91 1990-1991 Curriculum Committee, Department of Environmental and Occupational Health (GSPH) 1990-1996 Chairperson, Curriculum Committee 1990-1995 Faculty Search Committee, Department of Environmental and Occupational Health (GSPH) 1991-1996 University of Pittsburgh Radiation Safety Committee 1993-1996 University of Pittsburgh Medical Center (UPMC) Safety Committee 1993-1995 AIDS Task Force 1993-1996 UPMC Accident Investigation Committee 1994-1996 University’s Accident Investigation Subcommittee; Chairperson 1993-1996 Environmental Health and Safety Committee and Biohazard Committee, UPMC/University of Pittsburgh’s Worker’s compensation Committee including the Claims Administration subcommittee 1993-1995 Pittsburgh Global Environmental Institute Committee initiated by Dr. Detre 1994-1995 University of Pittsburgh Medical Center Airport Health Center, Planning and Business Committee 1993-1996 Budget and Planning Committee, GSPH, University of Pittsburgh 1994-1996 GSPH Laision to create joint MD/MPH program with the School of Medicine 1995-1996 University’s Fact-Finding Committee for the Performance of Dean Mattison

2. Intramural – MCP Hahnemann, Allegheny Univ of the Health Sciences, Drexel Univ

1996 Search Committee for Director of the Institute for Women’s Health Group facilitator for Symposium: Health Education in Cyberspace 1996-1998 School of Public Health Faculty Development Committee 1996-2002 School of Public Health Appointment and Promotions Committee School of Public Health Executive Committee of the Faculty MD-MPH Program Committee School of Public Health Educational Coordinating Committee; Chair 1997 Group Co-Chair “Basic Research/Clinical Interactions”, Clinical Research Conf. 1997-1998 Faculty Representative to University Leadership Committee School of Public Health First Year Curriculum Committee, Chair Faculty Member of the Task Force for Educational Excellence, Office of Education Faculty Representative of the Resource Management Committee, Office of the General Counsel, Corporate Affairs Faculty Representative on the Trustee Award Winners Committee Faculty Representative on Academic Affairs Committee, AUHS Board of Trustees 1997-1999 Chair, Human Studies Review Committee, Institute of Cellular Therapeutics 1998-1999 Chair, Lifelong Learning Subcommittee, Task Force for Excellence Grievance Committee, School of Public Health 1999-2000 Provost Advisory Committee Academic Calendar Task Force Committee Dean Search Committee, School of Public Health University Tenure Committee, MCP Hahnemann University 1999-2002 University Biosafety Committee (Chair 2001-2002)

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3. Intramural – University of Louisville

2002-present University Environmental Safety and Health Taskforce 2002-present Curriculum Committee, School of Public Health and Information Sciences 2003 Chair, Search Committee, Department of Bioinformatics and Biostatistics Chair Chair, Search Committee, Dept. of Epidemiology and Clinical Investigation Sciences Chair 2003-Present University Conflict of Interest Task Force Internal Advisory Committee, NIEHS Program Project Grant: Cardiovascular Toxicology of Environmental Aldehydes, PI: Aruni Bhatnagar 2003-2008 Promotion and Tenure Committee, School of Public Health and Information Sciences 2004 University Distinguished Teaching Award Committee 2005 Chair, Search Committee, SPHIS Dept. of Health Management and Cognitive Sciences Chair Chair, Search Committee, SPHIS Dept. of Health Knowledge and Information Sciences Chair 2005-2006 Associate Director, Master of Public Health, School of Public Health and Information Sciences 2005-2008 Chair, Environment Health Committee, Partnership for a Green City Project 2005-present Research Advisory Team, Community Farm Alliance 2006-present Committee for Review of Individual Financial Interests in Research 2008-present Sustainability Council, Education and Research Committee, Research in Sustainability subcommittee 2010 Member, Ad Hoc committee for Executive Vice President for Health Affairs 2010-present Member, Search committee for Executive Vice President for Health Affairs 2010 Chair, Search Committee for Department of Bioinformatics and Biostatics Chair 2010-2013 Member, Committee for the Review of Individual Financial Interests in Research 2012 Chair, Search Committee for SPHIS Department of Bioinformatics and Biostats Chair 2013-present Institutional Biosafety Committee, Member

4. Extramural Committee and Board Membership 1991-Present American Industrial Hygiene Association Editorial Review Board Member 1992 Agency for Toxic Substances and Disease Registry (ATSDR): Immune Biomarkers - Immunodeficiency Workshop 1992-1994 American College of Occupational and Environmental Medicine (ACOEM): Basic Curriculum Committee Chair 1992 ATSDR Workshop: Pulmonary Study on Methods for Testing and Evaluation of Adult Respiratory Health Effects in Community Investigations 1992-1996 Tri-State Occupational Medical Association: Delegate to ACOEM National Meeting 1992-1993 Institute of Medicine: Vice-Chair for Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides 1992-1994 National Institute for Occupational Safety and Health (NIOSH): Committee on Occupational Safety and Health, Objectives for Healthy People 2000 1992-1996 Allegheny County Medical Society: Occupational Medicine Committee 1993 Pittsburgh Health Group/Pittsburgh Novokuznetsk Sister Cities Committee: Member to visit Novokuznetsk, Russia 1993-1996 Harmarville Rehabilitation Center: Medical Consultant 1994-1995 National Occupational Safety and Health Educators Association (NOSHEA), Secretary 1994 ATSDR Workshop: The Role of Biomarkers in Field Studies of Environmentally Associated Cancers; Group 1, Cancers of Childhood ALA/ATS International Conference: Clinical Topics in Pulmonary Medicine

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Chair, Symposium and Molecular Epidemiology in Enviro and Occ Health 1994-1995 Institute of Medicine: Chair for Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides 1994-1996 ATS/ALA EOH Program Committee 1998-2002 Member: Asthma Task Force, City Health Department, Philadelphia, PA 1995-2002 Western Pennsylvania Safety Council - Board member 1997 ATSDR Conference “Environmental Medicine: Tools for Your Practice”: Planning Committee organized by Dept. of Public Safety, Bureau of Health, City of Chester in collaboration with Chester Board of Health, Crozer-Chester Medical Center, and Dept. of Family Medicine of Allegheny University of the Health Sciences. 1997 Sub-Committee Member: 21st Century Environment Commission authorized by Executive Order of the Governor of Pennsylvania 1997-1998 Institute of Medicine: Chair for Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides Journal of Occupational Hearing Loss, Editorial Board Member American Thoracic Society (ATS) Assembly on Environmental & Occupational Health Long Range Planning Committee - Member 1998-1999 Environmental Health Program Advisory Committee, Temple Univ., Phil, PA 1998-2002 Residency Advisory Committee Member, Thomas Jefferson University / Univ. of Pennsylvania, School of Medicine, Philadelphia, PA 1998-2003 Committee on Exposure Reconstruction Modeling for Agent Orange Exposure in Vietnam Veterans, Institute of Medicine, Washington, DC 1999-2000 Chair, Committee to Review the Evidence Regarding Link Between Exposure to Agent Orange and Diabetes. Institute of Medicine, Washington, DC 2000-2001 Member, Strategies for Small “n” Participant Clinical Research Trials, Institute of Medicine, Washington, DC 2000-2002 Chair, Environmental and Occupational Health Assembly Long Range Planning Committee of the American Thoracic Society. 2000-2005 Scientific Advisory Panel of the Western Canada Study on Animal and Human Health Effects Associated with Flare Emissions 2001-2002 Kiev, Ukraine – Philadelphia PA AIHA Health Partnership Project (funded by USAID) 2001-2007 Board on Health Promotion and Disease Prevention, Institute of Medicine, Washington, DC 2002-2004 Committee to Assess Poison Prevention, Institute of Medicine, Washington, DC 2003-2005 Chair, Committee to Assess Distribution of KI in the event of a Nuclear Incident, National Research Council, Washington, DC Chair, Environmental and Occupational Health Assembly, American Thoracic Society Board, American Thoracic Society Chair, Committee on Superfund Site Assessment and Remediation in the Coeur D’Alene River Basin 2005-2006 Chair, Disposition of the Air Force Health Study Coordinator, Review of Gulf War and Health Phase III

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2005-2008 Committee Member, Environmental Roundtable-Centers for Health Research, Institute of Medicine, Washington, DC 2006-2008 Committee Member, STAR 5.30 Stakeholder Group, Air Pollution Control District, Louisville, KY 2006-present Committee Member, Wet Weather Team Stakeholder Group, Metro Louisville Government 2010-2011 Chair, National Academy of Sciences, Institute of Medicine Committee on the Long-Term Health Consequences of Exposure to Burn Pits in Iraq and Afghanistan 2010-present NIH/NICHD National Children’s Study Publications Committee 2011-present NIH/NICHD National Children’s Study Publications Committee liaison for Environmental Sample Challenges Writing Team; lead reviewer for team 16’s manuscript 2011-present Chair, IOM Committee on Air Force Health Study (Ranch Hand) Data and Biospecimens Available for Research, Washington, DC 2011-present Chair, National Academy of Sciences, Institute of Medicine Committee on Epidemiologic Study: Shipboard Hazard and Defense II (SHAD II) 2012 Member, IOM Group on Pre-Study Guidance Materials for Committee Chairs

Study Sections and Grant Review Committees 1990 Member of an NIH Extramural Ad Hoc Review Committee to evaluate responses to a National Cancer Institute RFP for support services for epidemiological and immunological studies of retro viral diseases 1990 Member of special NIH study section: Small Grants for Epidemiology (NCI) 1991 Member of Grant Review Committee for the International Society of Environmental Epidemiology to review grants commissioned by the Mexican Government to address environmental concerns in Latin America Member of National Institute of Occupational Safety and Health Site Visit Team: California-North Educational Resource Center 1994 Member of Site Visit Team to review NIOSH funded Occupational and Environmental Medicine Training Program; University of Florida at Tampa, FL ,University of Southern California at Los Angeles, CA, and University of Texas Health Science Center in Houston, TX 1994-1995 Member of the Competitive Medical Research Fund (CMRF) Grant Review Committee, University of Pittsburgh Medical Center, Research-Health Sciences, May 1995 Member of Site Visit Team to review NIOSH funded Occupational and Environmental Medicine training Program; Meharry Medical College of Nashville, TN Member of Pittsburgh Cancer Institute (PCI) Internal Grant Review Committee Member of West Virginia University External Grant Review Committee 1996 Member of External Review Committee to review NIOSH Grant Funding Strategies Member of Site Visit Team to review the University of Cincinnati graduate program in the Department of Environmental Health/Division of Occupational Medicine Member of Site Visit Team to review Educational Resource Center at the University of Washington, Seattle, WA Member of Site Visit Team to review ERC in Department of Work Environmental at University of Massachusetts - Lowell 1997 Primary Viewer of the Reverse Site Visit Team to review ERC of Interamerican College of Physicians (Occupational Medicine) Long CV- 3/24/14 Page 13 of 35 CURRICULUM VITAE DAVID J. TOLLERUD, M.D., M.P.H.

Member of Reverse Site Visit Team to evaluate University of Massachusetts - Lowell (EPI Program Member of Site Visit Team to evaluate the training grant application for the University of Utah Educational Resource Center, Salt Lake City, UT Member of Site Team to review grant application for University of Alabama ERC, Birmingham, AL Member, ATSDR Peer Review Committee to review the draft protocol for "Evaluation and Other Health Effects from a Chlorine Release" 1997 Member, ATSDR/CDC Peer Review Committee to review the Draft Final Report entitled, “A Medical Follow-Up of Immune Biomarkers in Children with Elevated Blood Levels”. 1998 Member, ATSDR/CDC Peer Review Committee to review the Draft Final Report “Alberton Chlorine Spill” Member, NIH/NIEHS Peer Review Committee to evaluate RFA 97-004, “Centers for Children’s Environmental Health and Disease Prevention” proposal submissions 1998 Member, NHLBI Peer Review Committee to evaluate RFA HL 98-0005, “Origins of Asthma in Early Life” 1998-2003 Member, NIEHS Study Sections 2000-2005 Member, International Scientific Advisory Panel to Canadian Government to oversee multi- million dollar environmental study of oil and gas industry in Western Canada. 2001-2003 Chair of NIEHS Peer Review Committees to review K23 Grant Applications 2003 Chair, NIEHS Special Emphasis Panel to Review Innovative Environmental Toxicology proposals 2003 Review Coordinator of NAS Committee on Gulf War and Health: Literature Review of Pesticides and Solvents. Board on Health Promotion and Disease Prevention. Gulf War and Health Volume 2, Insecticides and Solvents, National Academies Press, Washington, DC, 2003. 2004 Review Coordinator of NAS Committee to review National Research Council Reports. Final draft, Veterans and Agent Orange: Presumptive of Association between Exposure and Respiratory Cancers, National Academies, 2004. 2004 Reviewer Coordinator of NAS Committee on Gulf War and Health: Literature Review of Selected Environmental Particulates, Pollutants, and Synthetic Chemical Compounds. Board on Health Promotion and Disease Prevention. Gulf War and Health Volume 3, Fuels, Combustion Products, and Propellants, National Academies Press, Washington, DC, 2004. 2005- Member, Institute of Medicine Peer-Review Reports, NIH Study Sections and Editorial Boards 2005-Present Member NIEHS Study Sections 2006 Reviewer, National Institute for Environmental Health Science, Environmental Health Perspective, “Microarray Analysis of Gene Expression in Peripheral Blood Mononuclear Cells from Dioxin-Exposed Human Subjects 2009 Reviewer, NIOSH Education and Research Center Site Visit, University of Washington, Seattle, WA, Dec 17-18 Review Committee Chair, National Institute for Environmental Health Science, RFA ES09-001, “Research to Action: Assessing and Addressing Community Exposures to Environmental Contaminants” 2010 Chair, NIEHS Special Emphasis Panel: Breast Cancer and Environmental Research Center Review (ZES1-LKB-V02), Mar 11-13

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Reviewer, RFA ES-09-008, Limited Competition: Continuation of Studies on Early Environmental Exposures and Human Puberty (U01), May Chair, NIEHS Special Emphasis Panel: Pathway to Independence/Career Development Review (ZES1 LKB-J-K9), July 19 Reviewer and Panelist, National Academy of Sciences, Institute of Medicine, Committee to Review the Federal Response to the Health Effects Associated with the Gulf of Mexico Oil Spill, Tampa, FL, Sep 21-22 2011 Chair, NIH/NIEHS Review of Deepwater Horizon Disaster Research Consortia (U19), Research Triangle Park, NC, Apr 6-8 2012 Reviewer, International Journal of Mass Emergencies and Disasters Chair, NIEHS Review of Planning Grants for Hubs of Interdisciplinary Research & Training in Global Environmental & Occupational Health (ZES1-SET-D(GH)1), Chapel Hill, NC. Jun 25-26 2013 Chair, NIEHS P30 Core Centers Program applications review committee, Research Triangle Park, NC, Jul 24-26

PUBLICATIONS

Original Reports in Peer Reviewed Journals: 1. Tollerud DJ, Weiss ST, Elting EH, Speizer FE, Ferris BG, Jr. The relationship of respiratory symptoms in tunnel and turnpike workers to cigarette smoking and automobile exhaust. Arch Environ Health 1983; 38:334-340. 2. Tollerud DJ, Blattner WA, Fraser MC, Brown LM, Pottern L, Shapiro E, Kirkemo A, Shawker TH, Javadpour N, O'Connell K, Stutzman RE, Fraumeni JF. Familial testicular cancer and urogenital developmental anomalies. Cancer 1985; 55:1849-1854. 3. Tollerud DJ, Brinton LA, Stone BJ, Tobacman JK, Blattner WA. Mortality from multiple myeloma in North Carolina furniture workers. JNCI 1985; 74:799-801. 4. Ildstad ST, Tollerud DJ, Bigelow ME, Remensnyder JP. Squamous cell carcinoma of the head and neck at the Massachusetts General Hospital: a comparison of biologic characteristics in men and women. Surgery 1986:99:7-13. 5. Ildstad ST, Tollerud DJ, Bigelow ME, Remensnyder JP. Early Recognition of oral cancers in the elderly. Geriatric Med Today 1986; 5(12):33-38. 6. Newman MJ, Light BA, Weston A, Tollerud DJ, Clark JW, Mann DL, Blackman JP, Harris CC. Detection and characterization of human serum antibodies to polycyclic aromatic hydrocarbon diol-epoxide DNA adducts. J Clin Investigation 1988; 82:145-153. 7. Ildstad ST, Tollerud DJ, Weiss RG, Ryan DP, McGowan MA, Martin LW. Duplications of the alimentary tract: clinical characteristics, preferred treatment, and associated malformations. Ann Surgery 1988; 208:184-189. 8. Tollerud DJ, Clark JW, Brown LM, Neuland CY, Mann DL, Pankiw-Trost LK, Blattner WA, Hoover RN. Association of cigarette smoking with decreased numbers of circulating natural killer cells. Am Rev Resp Dis. 1989; 139-194-198. 9. Tollerud DJ, Wesseler TA, Kim CK, Baughman RP. Use of a rapid differential stain for identifying pneumocystis carinii in bronchoalveolar lavage fluid. Chest 1989; 95-494-497. 10. Ildstad ST, Tollerud DJ, Bigelow ME, Remensnyder JP. A multivariate analysis of determinants of survival for patients with squamous cell carcinoma of the head and neck. Ann Surg. 1989; 209:237-241.

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11. Tollerud DJ, Clark JW, Brown LM, Neuland CY, Mann DL, Pankiw-Trost, LK, Blattner WA, Hoover RN. The effects of cigarette smoking on T-cell subsets: a population-based survey of healthy caucasians. Am Rev Resp Dis 1989; 139:1446-1451. 12. Brown LM, Tollerud DJ, Pottern LM, Clark JW, Kase R, Blattner WA, Hoover RN. Biochemical epidemiology in community-based studies: practical lesions from a study of T-cell subsets. J Clin Epidemiology 1989;42:561-568. 13. Tollerud DJ, Clark JW, Brown LM, Neuland CY, Pankiw-Trost LK, Blattner WA, Hooker RN. The influence of age, race, and gender on peripheral blood mononuclear cell subsets in healthy nonsmokers. J Clin Immunology 1989; 9:214-222. 14. Ildstad ST, Tollerud DJ, Noseworthy J, Ryckman F, Sheldan CA, McEnery PT, Martin LW. Renal transplantation in pediatric recipients. Transplantation Proceedings 1989; 21:1936-7. 15. Ildstad ST, Tollerud DJ, Weiss RG, Cox JA, Martin LW. Cardiac contusion in pediatric patients with blunt thoracic trauma. J Ped Surg 1990; 25:287-289. 16. Tollerud DJ, Brown LM, Blattner WA, Hoover RN. The influence of race on T-cell subset distributions. Mechanisms of B Cell Neoplasia. Springer-Verlag. New York, 1990. 17. Ildstad ST, Tollerud DJ, Noseworthy J, Ryckman F, Sheldon CA, Martin LW. The influence of donor age on graft survival in renal transplantation. J Ped Surg 1990; 25(1):134-139. 18. Ildstad ST, Stevenson RJ, Tollerud DJ, Martin LW. High apical insertion of the right diaphragm in an infant with right-sided bochdalek diaphragmatic hernia. J Pediatric Surgery 1990; 25(5):553-555. 19. Ildstad ST, Tollerud DJ, Weiss RG, Cox JA, Martin LW. Cardiac contusion in pediatric patients with blunt thoracic trauma. Journal of Pediatric Surgery 1990; 25(3):287-289. 20. Tollerud DJ, Ildstad ST, Brown LM, Clark JW, Blattner WA, Mann DL, Neuland CY, Pankiw-Trost L, Hoover RN. T-cell subsets in healthy teenagers: the transition to the adult phenotype. Clin Imm Immunopathol 1990; 56:88-96. 21. Caporaso NE, Tucker MA, Hoover RN, Hayes RB, Pickle LW, Issaq HJ, Muschik GM, Green-Gallo L, Buivys D, Aisner S, Resau JH, Trump BF, Tollerud DJ, Weston A, Harris CC. Lung cancer and the debrisoquine metabolic phenotype. J Natl Cancer Inst 1990; 82:1264-1272. 22. Boggs SS, Patrene KD, Austin CA, Vecchini F, Tollerud DJ. Latent deficiency of the hematopoietic microenvironment of aged mice as revealed in W/Wv mice given +/+ cells. Experimental Hematology 1991. 23. Tollerud DJ, O'Connor GT, Sparrow D, Weiss ST. Asthma, hay fever, and phlegm production are associated with distinct patterns of allergy skin test reactivity, eosinophilia, and serum IgE level: The normative aging study. Am Rev Resp Dis 1991; 144:776-781. 24. Tollerud DJ, Brown LM, Clark JW, Neuland CY, Mann DL, Pankiw-Trost L, Blattner WA. Cryopreservation and long-term liquid nitrogen storage of peripheral blood mononuclear cells for flow cytometry analysis: Effects on cell subset proportions and fluorescence intensity. J Clin Lab Analysis 1991; 5:255-261. 25. Tollerud DJ, Brown LM, Blattner WA, Mann DL, Pankiw-Trost L, Hoover RA. T-cell subsets in healthy black smokers and nonsmokers. Evidence for ethnic group as an important response modifier. Am Rev Resp Dis 1991; 144:612-616. 26. Tollerud DJ, Weiss ST, Leung DYM. Elevated soluble interleukin-2 receptors in young healthy cigarette smokers. Int Arch Allergy Appl Immunol 1992; 97:25-30. 27. Baughman R, Lower EE, Flessa H, Tollerud DJ. Thrombocytopenia in the Intensive Care Unit. Chest 1993;1234-7. 28. Sherman CB, Tollerud DJ, Heffner LJ, Speizer FE, Weiss ST. Airways Responsiveness in Young Black and White Women. Am Rev Resp Dis 1993; 148:98-102.

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29. Tollerud DJ, Kurman CC, Morris-Brown L, Nelson DL, Blattner WA. Racial Variation in Serum Soluble Interleukin-2 Receptor Levels: A Population-based Study of Healthy Smokers and Nonsmokers. J Immunol Immunopathol 1994; Vol.70, No.3, March, 274-279. 30. Karol MH, Tollerud DJ, Campbell TP, Fabbri L, Maestrelli P, Saetta M, Mapp Ce. The Predictive Value of Airways Hyperresponsiveness and Circulating IgE for Identifying Types of Responses to Toluene Diisocyanate Inhalation Challenge. Am Rev Resp Dis 1994; 149:611-615. 31. Diamondstone LS, Tollerud DJ, Fuchs D, Wachter H, Brown LM, Maloney E, Kurman CC, Nelson DL, Blattner WA. Factors Influencing Serum Neopterin and 2-Microglobulin Levels in a Healthy Diverse Population. J Clin Immunol 1994; Vol 14, No.6:368-374. 32. Neas LM, Dockery DW, Koutrakis P, Tollerud DJ, Speizer FE. The association of ambient ir pollution with twice daily peak expiratory flow rate measurements in children. Am J Epidem 1995; 141:111-22. 33. Tollerud DJ, Brown LM, Blattner WA, Weiss ST, Maloney EM, Kurman CC, Nelson DL, Hoover RN. Racial Differences in Serum Immunoglobulin Levels: Relationship to Cigarette Smoking, T-cell Subsets and Soluble Interleukin-2 Receptors. J Clin Lab Analysis 1995;9:37-41. 34. Satoh S, Kramarik JA, Tollerud DJ, Karol MH. A Model for Assessing the Respiratory Hypersensitivity Potential of Chemical Allergens. Toxicology Letters 1995;78:57-66. 35. Satoh T, Tollerud DJ, Guevarra L, Rake Y, Nakadate T, Kagawa J. Chemiluminescence assays for cytokines in serum: influence of age, smoking, and race in health subjects. Japanese J of Allergology 1995;44(7):661-9. 36. Shvedova AA, Satoh T, Tollerud DJ, Guevarra L, Karol MH. Elevated Levels of IL-6, INF-, and TNF- in Mice in Response to Cotton Dust are Modulated by ANTI-TNF- Antiserum. Experimental Lung Research 1996;22:149-161. 37. Krasnow JS, Tollerud DJ, Naus G, DeLoia JA. Endometrial Th2 cytokine expression throughout the menstrual cycle and early pregnancy. Human Reproduction 1996; 11 (8):1747-54. 38. Moyna NM, Acker GR, Fulton JR, Weber K, Goss FL, Robertson RJ, Tollerud DJ, Rabin BS. Lymphocyte function and cytokine production during incremental exercise in active and sedentary males and females. Int J Sports Med 1996; 17(8):585-591. 39. Newton-Nash DK, Tollerud DJ, Guevarra L, Gill JC. Interferon- Secretion Defects in Hemophilia A Patients Receiving Highly Purified Plasma-Derived or Recombinant Factor VIII. Br J of Hematology 1996 Dec; 95(3):554-560. 40. Maloney E, Brown LM, Diamondstone L, Blattner WA, Fuchs D, Wachter H, Tollerud DJ. Longitudinal Changes in Cellular & Soluble Immune Parameters in Healthy Adults. J Clin Lab Anal 1997;11(4):190-195. 41. Keman S, Willemse B, Tollerud DJ, Guevarra L, Schins RP, Borm PJA. Blood Interleukin-8 Production in Chemical Workers with Bronchitic Symptoms. Am J Ind Med 1997 Dec; 32(6):670-673. 42. Satoh T, Brown LM, Maloney E, Blattner WA, Tollerud DJ. Soluble Interleukin-2 Receptors, Beta-2 Microglobulin, and Neopterin Levels in Healthy Teenagers: Relationship to Age, Gender, Race and T-cell Subsets. Clin Immunol Immunopathol 1998; 88 (2):176-182. 43. Hacken N, Oosterhoff Y, Kauffman H, Guevarra L, Satoh T, Tollerud DJ, Dirkje P. Elevated Levels of Serum Interferon- in Subjects with Atopic Asthma Correlate with Increased airway Responsiveness and 16-04 h PEF-variation. Eur Resp J 1998; 11(2):312-316. 44. Woodin MA, Hauser R, Siegel PD, Tollerud DJ, Lewis DM, Liu Y, Smith T, Christiani DC. Nasal Lavage Inflammatory Mediators as Biomarkers of Upper Airway Exposure to Fuel Oil Ash. Am J Resp Crit Care Med 1998; 158(1):182-187. 45. Peele P, Tollerud DJ. Managed Care in Workers’ Compensation Plans. Ann Rev Public Health 2001; 22:1-14.

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46. Rodricks JV, Collins JJ, Farland WH, Tollerud DJ. Contrasting Roles of Epidemiology in Dioxin-Related Policy: Lessons Learned. Amer Journal of Epidemiology 2001 Dec 15; 154(12 Suppl):S43-9. 47. Litonjua A, Sparrow D, Guevarra L, O’Connor G, Weiss ST, Tollerud DJ. Serum interferon-gamma is associated with longitudinal decline in lung function among asthmatic patients: the Normative Aging Study. Ann Allergy, Asthma & Immunology 2003; 90:422-428 . 48. Tsunoda M, Litonjua A, Kuniak MP, Weiss ST, Satoh S, Tollerud DJ. Serum cytokine levels, cigarette smoking and airway responsiveness among pregnant women. Int Arch Allergy and Immunol 2003; 130:158-164. 49. Tsunoda M, Tsunoda H, Guevarra L, Tollerud DJ. The relationship between serum cytokine levels and common laboratory tests in healthy Japanese men. Env Health and Prev Med 2003; 8:6-12. 50. Peele PB, Tollerud DJ. Depression and Occupational Injury: Results of a pilot investigation. Journal of Occupational and Environmental Medicine 2005, Apr;47(4):424-7. 51. Min Li, McDow SR, Tollerud DJ, Mazurek MA. Quantitation, Detection and Measurement Precision of Organic Molecular Markers in Urban Particulate Matter from Philadelphia, PA. Journal of Air & Waste Management Association, Proceedings from 98th Annual Conference and Exhibition, June 2005. 52. Min L, McDow SR, Tollerud DJ, Mazurek MA. Seasonal abundance of organic molecular markers in urban particulate matter from Philadelphia, PA. Atmospheric Environment Vol 40, Issue 13, April 2006, Pages 2260-2273. 53. Hughes TS, Muldoon SB, Tollerud DJ. Underestimation of mortality due to chronic obstructive pulmonary disease (COPD) in Kentucky. Journal of the Kentucky Medical Assoc 104(8):331-9, August 2006. 54. Rice C, Brewer D, Hornung R, Ho M, Tollerud DJ. When 4/2 Does Not Equal 2: Approaches To Extending A Categorical Exposure Rank to a Quantitative Exposure Range. Compendium publication of Collegium Ramazzini meeting, Capri, Italy. October 2007. 55. Mo Y, Zhu X, Hu X, Tollerud DJ, Zhang Q. Cytokine and NO release from peripheral blood neutrophils after exposure to metal nanoparticles: in vitro and in vivo studies. Nanotoxicology. June 2008; 2(2):79-87 56. Wan R, Mo Y, Zhang X, Chien S, Tollerud DJ, Zhang Q. Matrix metalloproteinase 2 and 9 are induced differently by metal nanoparticles in human monocytes: The role of oxidative stress and protein tryosine kinase activation. Toxicology and Applied Pharmacology 2008; 233:276-285. PMID: 18835569 57. Mo Y, Wan R, Chien S, Tollerud, DJ, Zhang Q. Activation of endothelial cells after exposure to ambient ultrafine particles: the role of NADPH oxidase. Toxicology and Applied Pharmacology 2009; 236:183-193. PMID: 19371610 58. Mo Y*, Wan R*, Wang J, Chien S, Tollerud DJ, Zhang Q (*co-first author). Diabetes is associated with increased sensitivity of alveolar macrophages to urban particulate matter exposure. Toxicology, 2009; 262: 130-137. PMID: 19505525 59. Bahr, DE, Hughes T, Aldrich TE, Silver KZ, Brion GM, Tollerud D “Cohort Follow-up: the 21st Century Procedures,” Journal of Registry Management, 2009, 36:1:16-20. 60. Adams KJ, DeBeliso M, Sevene-Adams P, Berning J, Miller T, Tollerud DJ. “Physiological and Psychophysical Comparison Between a Lifting Task with Identical Weight but Different Coupling Factors.” Journal of Strength and Conditioning Research, Feb 2010, Vol 24, 2:307-312. 61. Chan MC, Hughes TS, Muldoon S, Aldrich T, Rice C, Hornung R, Brion G, Tollerud D, and The Paducah Gaseous Diffusion Plant Project Team. “Mortality Patterns Among Paducah Gaseous Diffusion Plant Workers” JOEM, Jul 2010, 52(7):725-732. 62. Aldrich TE, Seidu D, Bahr D, Freitas S, Brion GM, Tollerud D. and The Paducah Gaseous Diffusion Plant Project Team. “Time-Period Mortality Patterns in a Gaseous Diffusion Plant Workforce.” IJOMEH, 2010; 23(2): 145-151.

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63. Mo Y*, Wan R*, Wang J, Yu J, Tollerud DJ, Chien S, Zhang Q. (*co-first author) Intracellular delivery of ATP enhanced healing process in full thickness skin wounds in diabetic animals. American Journal of Surgery, 2010; 199: 823-832. PMID: 20609726 64. Bahr DE, Aldrich TE, Seidu D, Brion GM, Tollerud DJ, and the Paducah Gaseous Diffusion Plant Project Team. “Occupational Exposure to Trichloroethylene in Paducah Gaseous Diffusion Plant Workers” [IJOMEH, 2011;24(1):1 – 11; DOI 10.2478/s13382-011-0007-1] 65. Wan R*, Mo Y*, Chien S, Li Y, Li Y, Tollerud DJ, and Zhang Q. (*co-first author) The role of hypoxia inducible factor-1α in the increased MMP-2 and MMP-9 production by human monocytes exposed to nickel nanoparticles. Nanotoxicology 2011, 5, 568-582. PMID: 21401309 66. Mo Y*, Wan R*, Feng L, Chien S, Tollerud DJ, Zhang Q (* co-first author). Combination effects of cigarette smoke extract and ambient ultrafine particles on endothelial cells. Toxicology in Vitro 2012, 26: 295-303. PMID: 22178768 67. Leventhal J, Abecassis M, Miller J, Gallon L, Ravindra K, Tollerud DJ, King B, Elliott MJ, Herzig G, Herzig R, Ildstad S. Chimerism and Tolerance Without GVHD or Engraftment Syndrome in HLA-Mismatched Combined Kidney and Hematopoietic Stem Cell Transplantation. Sci Transl Med 7 March 2012: Vol. 4, Issue 124, p. 124ra28.

68. Wan R*, Mo Y*, Feng L, Chien S, Tollerud DJ, Zhang Q. DNA damage caused by metal nanoparticles: the involvement of oxidative stress and activation of ATM. Chemical Research in Toxicology, 2012;25: 1402-1411 (Highlight in issue; 2012; 25(7):1283). PMID:22559321

69. J Leventhal, J Miller, M Abecassis, DJ Tollerud, and ST Ildstad. Evolving Approaches of Hematopoietic Stem Cell–Based Therapies to Induce Tolerance to Organ Transplants: The Long Road to Tolerance. J. Clinical Pharmacology & Therapeutics, 2012; 93(1):36-45. PMC3621140

70. Leventhal J, Abecassis M, Miller J, Gallon L, Tollerud D, King B, Elliott MJ, Bozulic LD, Houston C, Ildstad ST. Tolerance induction in HLA disparate living donor kidney transplantation by donor stem cell infusion: durable chimerism predicts outcome. Transplantation. 2013 Jan 15;95(1):169-76. PMC3531567 71. Feng L *, Zhang Y*, Jiang M, Mo Y, Wan R, Jia Z, Tollerud DJ, Zhang X, Zhang Q. (*co-first author). Up- regulation of Gadd45α after Exposure to Metal Nanoparticles: the Role of Hypoxia Inducible Factor 1α. Environmental Toxicology, 2014 [in press] 72. Figgs L, Holsinger H, Freitas S, Aldrich TE, Brion GM, Tollerud DJ. Suicide among Arsenic Exposed Workers at the Paducah Gaseous Diffusion Plant in Paducah, KY (1953 – 2003) [In revision] 73. Aldrich TE, Freitas S, Brion GM, Tollerud DJ, and the Paducah Gaseous Diffusion Plant Project Team. “Impact of Adding Cancer Incidence Data to a Cohort Mortality Study” [In-preparation]. 74. Aldrich TE, Freitas S, Brion GM, Tollerud D, and the Paducah Gaseous Diffusion Plant Project Team. ”Case-Comparison Study of Suicides in a Cohort Mortality Study of an Uranium Enrichment Facility” [In Preparation] 75. Freitas S, Aldrich TE, Brion GM, Tollerud D, and the Paducah Gaseous Diffusion Plant Project Team. “Smoking-Attributable Lung Cancer Mortality in an Occupational Cohort” [In Preparation] 76. Hornung R, Rice C, Brewer D, Ho M, Aldrich T, Brion G, Tollerud D and the Paducah Gaseous Diffusion Plant Project Team. “Cancer risk among workers at the Paducah Gaseous Diffusion Plant” [In preparation]

Letters, Case Reports, and Book Chapters: 1. Tollerud DJ, Albano BA, Bia FJ. Anaerobic septic bursitis. Ann Intern Med 1979; 91:494. 2. Tollerud DJ, Clark JW, Brown LM, Neuland CY, Mann DL, Blattner WA, Hoover RN. Systemic lupus erythematosus with deficiency of the T4 epitope on T4 helper/inducer cells. N Engl J Med 1985; 313:1544.

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3. Wang HH, Tollerud DJ, Danar D, Hanff P, Gottesdiener K, Rosen S. Another Whipple-like disease in AIDS? N Engl J Med 1986; 314:1577-1588. 4. Tollerud DJ. Pleural Effusions in Manual of Clinical Evaluation: Strategies for Cost-Effective Care. Eds. Aronson and Delbanco. Little, Brown and Company, New York, 1988. 5. Ildstad ST, Stevenson RJ, Tollerud DJ, Martin LW. High apical insertion of the right diaphragm in an infant with right bochdalek diaphragmatic Hernia. J Pediatric Surgery 1990; 25:553-555. 6. Fallon H, Tollerud DJ (Committee Vice-Chair), Breslow N, Berlin J, Bolla K, Colditz G, Goetz C, Kaminski N, Kriebel D, Mottet NK, Neugut A, Nicholson W, Olshan A, Rodgers K, Sprince N, Weisel C. Institute of Medicne. Veterans and Agent Orange. Committee to Review The Health Effects of Herbicides Used in Vietnam. National Academy Press, Washington DC, 1993. 7. Tollerud DJ. Educational Opportunities in Occupational Medicine. A Practical Approach to Occupational and Environmental Medicine. McCunney RJ, ed. Little, Brown and Company, New York, 1994. 8. Muldoon SR, Tollerud DJ. Foundries and Steelmaking. Occupational and Environmental Respiratory Disease. Harper P, Balmes J. Schenker M. eds. Mosby, 1994;VIII:39. 9. Kuniak MP, Tollerud DJ. BULLETIN of the Allegheny County Medical Society. TB: Protecting Healthcare Workers. Allegheny County Medical Society, February 10, 1996;Vol.85, No.3. 10. Tollerud DJ, (Committee Chair). Institute of Medicne. Veterans and Agent Orange. Update 1996. Committee to Review The Health Effects of Herbicides Used in Vietnam. National Academy Press, Washington DC, 1997. 11. Hoel DG, Hammond SK, Koller LD, Loomis DP, Rappaport SM, Smith TJ, Tollerud DJ, Zeise L. Institute of Medicine. Characterizing Exposure of Veterans to Agent Orange and Other Herbicides Used in Vietnam: Scientific Considerations Regarding a Request for Proposals for Research.” Committee on the Assessment of Wartime Exposure to Herbicides Used in Vietnam. National Academy Press, Washington DC, 1997. 12. Tollerud DJ, (Committee Chair). Institute of Medicine, Veterans and Agent Orange. Update 1996. Committee to Review The Health Effects of Herbicides Used in Vietnam. National Academy Press, Washington, DC 1998 13. Tollerud DJ, (Committee Chair). Institute of Medicine, Herbicide/Doxin Exposure and Type 2 Diabetes, Committee to Review The Health Effects of Herbicides Used in Vietnam. National Academy Press, Washington, DC 2000 14. Ildstad ST, Centor RM, Davis E, Levin B, Miller ED, Olkin I, Tollerud DJ, Tugwell P. Institute of Medicine, Small Clinical Trials: Issues and Challenges, Committee on Strategies for Small-Number Participant Clinical Research Trials, National Academy Press, Washington, DC 2001 15. Hoel DG, Hammond SK, Koller LD, Loomis DP, Rappaport SM, Smith TJ, Tollerud DJ, Zeise L. Institute of Medicine. Characterizing Exposure of Veterans to Agent Orange and Other Herbicides Used in Vietnam: Interim Findings and Recommendations. Committee on the Assessment of Wartime Exposure to Herbicides Used in Vietnam. National Academy Press, Washington DC, 2003. 16. Tollerud, DJ, Emmett, EA. A Practical Approach to Occupational and Environment Medicine, 3rd edition. Editor: Robert McCunney. Chapter: Educational Opportunities. Lippencott Williams, Wilkins, PA, 2003; 209-217. 17. Tollerud DJ, Becker DV, Braverman LE, Keller RL, Langley KS, Maher TJ, Miller K, Reiners C H-J, Russel JJ, Volland RH, Wildsw EL, Williams ED, Zeise LA. National Research Council Distribution and Administration of Potassium Iodide in the Event of a Nuclear Incident. National Academies Press, Washington DC, 2004. 18. Guyer BG, Alexander JA, Blanc P, Emerson D, Hedges JR, Kamlet MS, Mickalide A, Pentel, Rumack BH, Schor DP, Spyker DA, Stergachis A, Tollerud DJ, Walker DK. Committee on Poison Prevention and

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Control. Forging a Poison Prevention and Control System. National Academies Press, Washington DC, 2004. 19. McDow, S, Tollerud, DJ. Occupational, Industrial, and Environmental Toxicology, 2nd Edition. Editor: Michael Greenberg. Chapter: Outdoor Air Pollution. 2003/2005: 622(14). 20. Weinrich M, Tollerud DJ, Hornung C, Ildstad S. Chapter: Small Clinical Experiments Translational and Experimental Clinical Research. Lippincott, Williams & Wilkins, 2005:19, 203-208. 21. Tollerud, DJ (Committee Chair): National Academy of Sciences, Institute of Medicine. Committee on the Dispositon of the Air Force Health Study. National Academies Press, Washington, DC. 2006. 22. Tollerud, DJ (Committee Chair): National Academy of Sciences, Institute of Medicine. Long-Term Health Consequences of Exposure to Burn Pits in Iraq and Afghanistan (Committee Report). National Academies Press, Washington, DC. 2011 23. Mo Y, Wan R, Tollerud DJ, Zhang Q. Cancer and Inflammation Mechanisms: Chemical, Biological, and Clinical Aspects, Chapter: Nanomaterials. John Wiley & Sons ISBN: 978-1-118-16030-5, 2014 (in press)

SELECTED ABSTRACTS/PRESENTATIONS 1. Ildstad ST, Tollerud DJ, Bigelow ME, Remensnyder JP. Squamous cell carcinoma of the head and neck at the Massachusetts General Hospital: A fifteen year survey. (Meeting Abstract). Combined British and American Societies of Head and Neck Surgeons and Society of Surgical Oncology Annual Meeting, London, England, May 1987. 2. Ildstad ST, Tollerud DJ, Blattner W, Martin LW, Hoover R. Peripheral blood mononuclear cell subsets (PBMC) in healthy children. (Meeting Abstract). Annual meeting of the Federation of American Societies for Experimental Biology (FASEB), Las Vegas, NV, May 1988. 3. Ildstad ST, Tollerud DJ, Hoover RN. T-cell subsets in healthy children. (Meeting Abstract). American Pediatric Surgical Association Annual Meeting, Tucson, AZ, May 1988. 4. Ildstad ST, Tollerud DJ, Noseworthy J, Sheldon CA, Ryckman FC, Martin LW. Influence of pediatric donor age on graft survival in cadaveric renal transplantation. (Meeting Abstract). The XII Congress of The Transplantation Society, Sydney, Australia, August 1988 5. ldstad ST, Tollerud DJ, Noseworthy J. Ryckman FC, Sheldon CA, Martin LW. Factors which influence renal allograft survival in pediatric transplant recipients. (Meeting Abstract). Clinical Immunology Society Annual Meeting, San Francisco, CA, November 1988. 6. Ildstad ST, Tollerud DJ, Noseworthy J, Ryckman FC, Sheldon CA, Martin LW. Influence of donor age on graft survival in renal transplantation (Meeting Abstract). American Pediatric Surgical Association Annual Meeting, Baltimore, MD, May 1989. 7. Tollerud DJ, Kurman CC, Morris-Brown L, Nelson DL, Blattner WA. The influence of race, gender and cigarette smoking on serum soluble interleukin-2 receptor levels. J Cellular Biochem 1991; Suppl. 15F:P562. (Presented at Keystone Symposium: Cytokines and Their Receptors, Keystone, CO. 1991). 8. Tollerud DJ, Morris-Brown LM, Blattner WA, Mann DL, Pankiw-Trost L, Hoover RN. Evidence for the influence of race on T-cell subset alterations associated with cigarette smoking. (Presented at the FASEB annual meeting, Atlanta GA, 1991). 9. Tollerud DJ, Blattner WA, Weiss ST, Brown LM, Maloney E, Hoover RN. The influence of race and cigarette smoking on serum immunoglobulin levels. Am Rev Resp Dis 1991; 143:A276 (Presented at the American Thoracic Society 1991 International Conference, Anaheim, CA. 1991). 10. Tollerud DJ, Mapp CE, Kramerik JA, Zocca E, Karol MH. The predictive value of airways hyperresponsiveness, circulating IgE and allergy skin testing for identifying responders to toluene diisocyanate inhalation challenge. Am Rev Resp Dis 1991; 143:A438 (Presented at the American Thoracic Society 1991 International Conference, Anaheim, CA. 1991). 11. Tollerud DJ, Harper JD, Kurman CC, Brown LM, Maloney E, Nelson DA, Blattner WA. Racial differences in serum soluble Interleukin-2 receptors among healthy teenagers. Journal of Cellular Biochemistry 1992; Suppl. 16B:281. (Presented at the Keystone Symposium: Cytokines in Growth, Development and Pathogenesis, Keystone, CO. 1992).

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12. Tollerud DJ, Fuchs D, Brown L, Maloney E, Blattner W. Influence of race and age on serum levels of beta-2 microglobulin. FASEB Journal 1992; 6:A1326. (Presented at the FASEB annual meeting, Anaheim, CA. 1992). 13. Tollerud DJ, Weiss ST, Brown LM, Maloney EM, Blattner WA. Racial differences in serum IgE level and eosinophil count in healthy smokers and nonsmokers. Am Rev Resp Dis 1992;145:A538. (Presented at the American Thoracic Society 1992 International Conference, Miami, FL. 1992). 14. Tollerud DJ, Guevarra L. Chemiluminescence Assays for Cytokines in Bronchoalveolar Lavage (BAL). Am Rev Resp Dis vol 146 April Suppl, 1993. Am Rev Resp Dis 1993;147:A229. (Presented at the 1993 American Thoracic Society Scientific Conference, San Francisco, CA. 1993). 15. Tollerud DJ, Sparrow D, Weiss S, Guevarra L. Chemiluminescence Assays for Human Cytokines. Journal of Cellular Biochemistry 1994; Suppl. 18A:26.(Presented at the 1994 Keystone Symposia, Keystone, CO. 1994). 16. Tollerud DJ, Sparrow DW, Guevarra L, O'Connor GT, Weiss ST. Relationship of Serum IL-5 Level to Longitudinal Rate of FEV1 Decline Among Asthmatics. Am Rev Resp Dis 1994;149:A913. (Presented at American Thoracic Society International Conference, Boston, MA. 1994). 17. Satoh T, Kramarik JA, Guevarra L, Tollerud DJ, Karol MH. Development of a Murine Model for Chemical Induced Asthma. (Presented at the American Thoracic Society International Conference, Boston, MA. 1994). 18. Guevarra L, Hanrahan JP, Tager IB, Tollerud DJ. Chemiluminescence ELIZA Assays for Cytokines in Cord Blood Samples: Application to Studies of Respiratory Disease in Infancy. Am Rev Resp Dis 1994;149:A391. (Presented at American Thoracic Society International Conference, Boston, MA. 1994). 19. Muldoon SR, Guevarra L, Calhoun WJ, Tollerud DJ. Evidence for Down-regulation of Monocyte IL-6 and GM-CSF Production by IL-10 in vitro: Application of Chemiluminescence ELIZA. (Presented at American Thoracic Society International Conference, Boston, MA. 1994). 20. Tollerud DJ, Sparrow DW, Guevarra L, O'Connor GT, Weiss ST. Serum Cytokines and Longitudinal Change in Pulmonary Function Among Asthmatics. Am J Resp Crit Care Med 1995;151:A566. (Presented at the 1995 American Thoracic Society International Conference, Seattle, WA. 1995.) 21. Satoh T, Siegel P, Short S, Petsonk E, Guevarra L, Tollerud DJ. Nasal Lavage Cytokine Levels Correlate with Seasonal Rhinitis. Am J Resp Crit Care Med 1995;151:A564. (Presented at the 1995 American Thoracic Society International Conference, Seattle, WA. 1995). 22. Kuniak MP, Tsunoda M, Weiss ST, Satoh T, Guevarra L, Tollerud DJ. Cigarette Smoking and Serum Cytokine Levels.AM J Resp Crit Care Med 1995;151:A565.(Presented at the 1995 American Thoracic Society International Conference, Seattle, WA. 1995). 23. Tsunoda M, Kuniak MP, Weiss ST, Satoh T, Guevarra L, Tollerud DJ. Serum Interferon (IFN-) and Airway Responsiveness. AM J Resp Crit Care Med 1995;151:A565. (Presented at the 1995 American Thoracic Society International Conference, Seattle, WA. 1995). 24. Newton Nash D, Tollerud DJ, Guevarra L, Foster PA, Gill JC, and Hemophilia Research Society Inhibitor Study Group. Aberrant Nitrogen-Stimulated Cytokine Production Profiles in Patients with Hemophilia A Treated with High Purity Factor VIII Concentrate. J Am Society Hema 1995; 3518:883A (Presented at American Society of Hematology, Seattle, WA. 1995). 25. Tollerud DJ, Guevarra L, Kuniak MP, Tager IB, Hanrahan JP. Serum Cytokine Levels: Effects of Ethnicity and Smoking. Am J Resp Crit Care Med 1996;153:A102 (Presented at 1996 International Conference of the American Thoracic Society, 1996). 26. Tsunoda M, Guevarra L, Tollerud DJ. Serum Cytokine Levels, Cigarette Smoking and Ethnicity Among Healthy Men. Am J Resp Crit Care Med 1996;153:A794 Am J Resp Crit Care Med 1996; 153:A794 (Presented at 1996 International Conference of the American Thoracic Society, 1996). 27. Keman S, Willemse B, Schins RPF, Guevarra L, Tollerud DJ, Borm PJA. Blood Cytokines as Markers of Respiratory Impairment in Chemical Workers. Am J Resp Crit Care Med 1996;153:A794 (Presented at 1996 International Conference of the American Thoracic Society, 1996).

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28. Woodin MA, Hauser R, Siegel PD, Tollerud DJ, Lewis DM, Liu Y, Smith T, Christiani DC. Nasal Lavage Inflammatory Mediators as Biomarkers of Upper Airway Exposure to Fuel Oil Ash. Am J Resp Crit Care Med 1996;153:A475 (Presentation at 1996 International Conference of the American Thoracic Society, 1996). 29. Ildstad S, Deeks S, Kaufman C, Michaels M, Colson Y, Hunt S, Tollerud DJ, Swift P, Daman L, Gutta P, Rimaklo C Heneine W, Capper J, Getty J, Volberding P. A Case Report of Baboon to Human Bone Marrow Transplantation. Am Public Health Assoc 1996;263:2005 (Presented at 1996 APHA Annual Meeting and Exposition, New York, NY. Nov. 1996). 30. Claycamp HG, Fromme KC, Sussman NB, Tollerud DJ. The Future of Risk Assessment: Machine Learning Applications in Characterizing Individual Risk. (Presentation at Biannual International Meeting of Risk Assessment & Policy Association, Alexandria, VA. March 1997). 31. Mangione S, Tollerud DJ. Asthma in Pennsylvania (PA): A Statewide Survey of All School Nurses. (Presented at CHEST 1997, 63rd Annual International Scientific Assembly of the American College of Chest Physicians, New Orleans, LA. 1997). 32. Mangione S., El-Gendy AL, Tollerud, DJ. Asthma in Pennsylvania: A State-Wide Comparison of Public and non-Public Schools. Proceedings from “The Challenge of Asthma”, an International Conference; 1997: page 14. The Lancet, London. 33. El-Gendy AI, Mangione S., and Tollerud, DJ. Asthma in Pennsylvania: A State-Wide Survey of All School Nurses. Chest 1997: 112(3):113S. Present at American Thoracic Society, 1999 International Conference, April 1999 34. Mangione S., El-Gendy AI and Tollerd, DJ. “Asthma in Pennsylvania School Children: A State-Wide Survey.” American Thoracic Society Annual Meeting (Abstract). Resp Crit Care Med 1998: 157(3):A64 35. Xiong D, Srulevich M, Francis A, Peele PB, & Tollerud DJ. The Effectiveness of a Training and Back Belt Program with Municipal Employees: Safety and Injury Prevention, American Public Health Association (Abstract)(1998) 36. Xiong D, Srulevich M, Francis A, Peele PB & Tollerud DJ. The Impact of a Muncipal Education and Back Belt Safety Program: Injury Prevention and Time Lost From Work. Pennsylvania Public Health Association Annual Meeting, (Abstract)(1998) 37. Tollerud DJ, Srulevich M, Xiong D, Francis A, Peele P. Cost-Effectiveness of a Back Safety Training and Back Belt Intervention.(Abstract). SOTAC Conference, Phoenix, AZ. 1998 38. Woodruff PG, Tollerud DJ, Nadel ES, Camargo, Jr. CA, Gillett M, Shapiro N, Giffey R, Guevarra L, Hanrahan JP. Serum IFN-, IL-4, and IL-5 Levels in Acute Asthma. Massachusetts Gen. Hosp., Beth Israel/Deaconess Medical Center, Brigham and Women’s Hospital, Boston, MA, and Allegheny University of the Health Sciences, Philadelphia, PA, USA (Present at American Thoracic Society, 1999 International Conference, San Diego, CA. April 1999) 39. Wright RJ, Kindlon DJ, Tollerud DJ, Guevarra L, Tager IB, Hanrahan JP. Does Maternal Stress Influence Polarization of TH2-Dominated Cytokine Production and Total IGE in Maternal and Cord Blood? (Present at American Thoracic Society, 1999 International Conference, April 1999) 40. Elia J, Bauer N, Villanueva A, Tollerud DJ. Asthma Prevalence Among Inner-City School Children: A Survey of 12 Philadelphia Middle Schools. Chest 1999;116:300S (Presented at American College of Chest Physicians, 1999 International Conference, October 1999). 41. Peele P, Tollerud DJ. Capitated Payment Systems: Provider Incentives and Patient Care. Southern Economic Association Meeting, New Orleans, LA. November 99 (Abstract) 42. Ildstad S, Crilley P, Kaufman C, Tollerud DJ, Cerrito P, Shadduck R, Lister J, Champlin R. Wingard J, LeMaistre F, Kanz L, Topolsky D, Lowder J, Herzig R. Graft engineering (II): A multivariate analysis of the facilitating cell protocol in advanced hematologic malignancy for mismatched donors. (Presented at Annual Meeting of the American Society of Hematology, New Orleans, LA. December 1999.) 43. Phillips BZ, Peele PB, Tollerud DJ: The Impact of Managed Care on the Treatment of Knee Injuries Among Municipal workers. (Presented at PPHA Meeting 1999)

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44. Peele P, Catullo VJ, Tollerud DJ. Capitated Payment Systems: Do Patients Get Adequate Care? Research to Action: The Role of Health Services Research, Association for Health Services. Washington, D.C. 1999 45. Ildstad S, Crilley P, Kaufman C, Tollerud D, Cerrito P, Shadduck R, Lister J, Champlin R. Wingard J, LeMaistre F, Kanz L, Topolsky D, Lowder J, Herzig R. Graft engineering (II): A multivariate analysis of the facilitating cell protocol in advanced hematologic malignancy for mismatched donors. (Meeting Abstract). 1999 Annual Meeting of the American Society of Hematology, New Orleans, LA, December 6, 1999 46. Tollerud DJ, Peele P, Stockman CK. “A Low Cost Approach to Evaluating Workplace Safety Programs.” American College of Preventive Medicine, Prevention 2000, Atlanta, GA. March 2000. 47. Mangione S, Elia J, Clayton R, Bauer N, Villanueva A, Tollerud DJ. Asthma Prevalence Among Inner-City School Children: A Three Year Follow-up of Two Philadelphia Middle Schools. Am J Resp Crit Care Med 2000;161:A796 (Presented at American Thoracic Society, 2000 International Conference, May 2000) 48. Lilly FRW, Tollerud DJ, Polansky M, Webb D. Urban Air Pollution & Childhood Asthma. Philadelphia Public Health Association (PPHA), Philadelphia, PA. April 2000 49. Ildstad ST, Crilley P, Kaufman CL, Tollerud DJ, Cerrito P, Perry T, Shadduck R, Lister J, Champlin R, Wingard J, LeMaistre C, Kanz L, Topolsky D, Bashey A, Herzig R.. A Graft Engineering Method to Allow Bone Marrow Transplantation (BMT) for more Highly Mismatched Recipients with Leukemia: Multivariate Analysis of a Phase I/II Protocol. Transplant 2000 Joint Meeting, Chicago, IL. May 2000 50. Ildstad ST, Herzig R, Kaufman C, Crilley P, Brozena S, McCarthy P, Granger D, Jones J, Dowling R, Baxter-Lowe LA, Tollerud DJ, Bentley F. Summary of a Phase II Protocol to Attempt to Induce Mixed Chimerism and Donor-Specific Tolerance to Renal and Cardiac Allografts. Transplant 2000 Joint Meeting, Chicago, IL. May 2000. 51. Bartle NA, Lloyd L, Villanueva A, Tollerud DJ. School of Public Health and Community Agencies Collaborate to Train Students and Improve Population Health. JACCHO/ASTHO Annual Meeting, Los Angeles, CA. July 2000. 52. Peele P, Tollerud DJ. “Capitation in Workers’ Compensation Insurance: Cost and Care.” Research in Health Financial Management (RHFM), Baltimore, MD. August 2000. 53. Peele P, Stockman CK, Tollerud DJ. Injury Surveillance Using Existing Workers’ Compensation Medical Claims Data, National Occup Injury Research Symposium, Pittsburgh, PA. October 2000. 54. Ildstad ST, Herzig R, Kaufman C, Tollerud DJ, Cerrito P, Perry T, Shadduck R, Lister J, Champlin R, Wingard J, LeMaistre C, Kanz L, Topolsky D, Bashey A, Venuto D, Herzig R. A Graft Engineering Method to Allow Bone Marrow Transplantation (BMT) for More Highly Mismatched Recipients with Leukemia: Multivariate Analysis of a Phase I/II Protocol. XVIII International Congress of the Transplantation Society, Rome. August 2000. 55. Rana U, Jurgens S, Mangione S, Elia J, Tollerud DJ. Asthma Prevalence Among High Absentees of Tow Philadelphia Middle Schools. Chest 2000;118:79S (Presented at American College of Chest Physicians, 1999 International Conference, October 1999) 56. Mangione S, Rana U, Jurgens S, Elia J, Tollerud DJ. Asthma Prevalence in Children with High Absenteeism. Am J Resp Crit Care Med 2001;163:A367 (Presented at American Thoracic Society, 2001 International Conference, May 2001) 57. Pruszko KL, Tollerud DJ, McDow S, Webb D, Li M. Asthma Morbidity and Exposure to Chemical Species in Particulates. (Presented at the American Public Health Association, October 2001) 58. Bartle N, Lloyd LE, Tollerud DJ, Villanueva A. School of Public Health and Community Agencies Collaborate to Train Practitioners and Improve Population Health. (Presented at the American Public Health Association, October 2001) 59. Erichsen HC, Bell EM, Tollerud DJ, Choi E, Jayaprakash A, Rothman N, Chanock SJ. Single Nucleotide Polymorphism in the IL12A Gene, Encoding for IL12-p35 is Associated with Plasma Levels of IL12 and GM-CSF. (Presented at American Society of Hematology Annual Meeting, December 2001)

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60. Murrain P, Paranzino G, Fine M, Tollerud DJ. Managing the environmental and public health impact of controlled building implosions: the Philadelphia experiment. (Presented at the American Public Health Association Annual Meeting, November 2002) 61. Yi M-S, Scott B, Tollerud DJ. Characterizing the health effects of occupational exposures among urban firefighters. (Presented at the American Public Health Association Annual Meeting, November 2002) 62. Raval-Nelson P, Hirschorn R, Tollerud DJ. An evaluation of the existing environmental health and safety training program for childcare providers in the City of Philadelphia. (Presented at the American Public Health Association Annual Meeting, November 2002) 63. Hussain A, Elia J, Mangione S, Tollerud DJ. Relationships between asthma morbidity and exposure to violence among school-aged, inner-city children. (Presented at the American Public Health Association Annual Meeting, November 2002) 64. Murrain P, Fine M, Tollerud DJ. Environmental and public health impacts of building implosions. (Presented at CDC meeting: Meeting the Challenge of Healthy People 2010: Preventing and Controlling Asthma, June 2003) 65. Husain A, Wright R, Tollerud DJ. Maternal and Cord Blood Cytokine Levels in Environmental Research: Importance of Ethnic Background. (Presented at American Public Health Association Annual Meeting, Nov 2003) 66. Husain A, Wright R, Tollerud DJ. Impact of Maternal Smoking on Maternal and Infant Cord Blood Cytokine Levels. (Presented at American Thoracic Society International Conference, May 2004) 67. Felker JM, Adams KJ, Fabian N, Hare J, Stamford BA, Harris C, Tollerud DJ. Metabolic costs of weight carrying exercise. (Presented at the American College of Sports Medicine Annual Meeting, Indianapolis, IN, June 2004) 61. Adams KJ, Fabian N, Sevene-Adams PG, DeBeliso M, Harris C, Berning JM, Tollerud DJ. Metabolic response to repetitive lifting tasks in females. (Presented at the American College of Sports Medicine Annual Meeting, Indianapolis, IN, June 2004) 62. Fabian NM, Adams KJ, Felker J, Hare J, Welgosh J, DeBeliso M, Tollerud DJ. Metabolic response to repetitive lifting protocols; predetermined vs. self-selected pace. (Presented at the American College of Sports Medicine Annual Meeting, Indianapolis, IN,. June 2004) 63. Peele PB, Tollerud DJ. Depression and occupational injury: results of a pilot investigation. J Occup Environ Med 2005. Apr;47(4):424-7. 64. Min Li, McDow SR, Tollerud DJ, Mazurek MA. Quantitation, Detection and Measurement Precision of Organic Molecular Markers in Urban Particulate Matter from Philadelphia, PA. Air & Waste Management Association, Proceedings from 98th Annual Conference and Exhibition, June 2005. 65. Hahn K, Moser A, Rice C, Hornung, R, Tollerud DJ. Estimating Chemical Exposure in a Uranium Enrichment, Gaseous Diffusion Plant. (Presented at American Industrial Hygiene Conference, San Diego, 2005) 66. Zhang Q, Zhang X, Kusaka Y, Tollerud DJ. Cytokines and NO release from peripheral blood neutrophils after exposure to metal nanoparticles: in vitro and in vivo study. 2nd International Symposium on Nanotechnology and Occupational Health, Radisson Hotel Metrodome, Minneapolis, Minnesota. Oct 2005. 67. Min L, McDow SR, Tollerud DJ, Mazurek MA. Seasonal abundance of organic molecular markers in urban particulate matter from Philadelphia, PA. Atmospheric Environment, Vol 40, Issue 13, April 2006, Pages 2260-2273. 68. Zhang Q, Zhu X, Dziubla T, Yu K, Tollerud DJ, Fisher AB. Oxidative-Stress Potency of Ultrafine Particles in Mouse Pulmonary Microvascular Endothelial Oxidative-Stress Cells. (Presented at American Thoracic Society Annual Conference, San Diego, CA, 2006) Published in Communique, May 2006. 69. Zhang Q, Mo Y, Shah N, Tollerud DJ. Activation of pulmonary microvascular endothelial cells in lungs following exposure to ultrafine particles. p77, Health Effect Institute Annual Conference, Chicago, Illinois, April 2007.

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70. Zhang Q, Yang Q, Mo Y, Tollerud DJ. Metalloproteinase and inflammatory cytokines produced by macrophages in response to different type of metal nanoparticles. (Oral presentation, ATS International Conference San Francisco, California, May 2007.) American Journal of Respiratory and Critical Care Medicine 2007; 175: A246. 71. Rice C, Brewer D, Hornung R, Ho M, Tollerud DJ. When 4/2 Does Not Equal 2: Approaches to Extending a Categorical Exposure Rank to a Quantitative Exposure Range. (Poster presentation at the Collegium Ramazzini meeting, Carpi, Italy. October 2007) 72. Edwards M, Lefebvre J, Carrico R, Tollerud DJ. Understanding the Impact of Asthma Among School-Age Children: A Pilot Study of Conducted at One Jefferson County Public Middle School. (Poster presentation at ResearchLouisville, Louisville, KY, October 2007) 73. Zhang Q, Wan R, Yang Y, Mo Y, Tollerud DJ. Induction of Matrix Metallopreteinase Expression in Human Macrophanges in Response to Different Types of Metal Nanoparticles. (Poster presentation at ResearchLouisville, Louisville, KY, October 2007) 74. Mo Y, Wan R, Shah N, Tollerud DJ, Zhang Q. Activation of Endothelial Cells After Exposure to Ultrafine Particles. (Poster presentation at ResearchLouisville, Louisville, KY, October 2007) 75. Reinhart N, Hughes T, Muldoon S, Aldrich T, Tollerud DJ. A Model for Occupational Health Studies of Uranium Enrichment Plants: The Paducah Gaseous Diffusion Plant. (Poster presentation at Research Louisville, Louisville, KY. October 2007 and APHA, Washington, DC, November 2007) 76. Zhang Q, Wan R, Yang Q, Mo Y, Tollerud DJ. Induction of matrix metalloproteinase 2 and 9 by human monocytes in response to different types of metal nanoparticles. (Poster presentation at 47th Annual Meeting of the Society of Toxicology, March 16-20, 2008) 77. Zhang Q, Mo Y, Wan Y, Shah N, Tollerud DJ. Activation of endothelial cells after exposure to ultrafine particles. (Poster presentation at the Health Effect Institute Annual Conference; Philadelphia, PA, April 27– 29, 2008) 78. Zhang Q, Mo Y, Wan R, Tollerud DJ. Activation of endothelial cells after exposure to ultrafine particles. 2008 ATS International Conference, Toronto, Canada, May 16-21, 2008, American Journal of Respiratory and Critical Care Medicine 2008; 177: A47 79. Ildstad ST, Cheerva A, Dampier C, Bertolone S, Kaufman C, Tollerud D, Herzig G, Herzig R. Campath Lymphodepletion Allows Reduced Intensity Conditioning to Establish Durable Mixed Chimerism in Patients with Sickle Cell Disease. (Meeting Abstract). American Transplant Congress, Toronto, ON, Canada, May, 2008. 80. Ildstad S, Cheerva A, Dampier C, Bertolone S, Tollerud D, Herzig G, Herzig R. Campath Lymphodepletion Allows Reduced Intensity Conditioning to Establish Durable Mixed Chimerism in Patients with Sickle Cell Disease. (Presented at Transplantation Society Conference, Sydney, Australia, Aug 10-14, 2008) 81. Wan R, Mo Y, Tollerud DJ, Zhang Q. Matrix metalloproteinase-2 and- 9 are induced differently by metal nanoparticler in human monocytes: the role of oxidative stress and protein tyrosine kinase activation. Nanotechnology Symposium 2008, October 03-04, 2008, Sullivan University, Louisville, Kentucky 82. Zhang Q, Mo Y, Wan R, Tollerud DJ. Pulmonary and systemic effects of transition nanoparticles. Nanotechnology Symposium 2008, October 03-04, 2008, Sullivan University, Louisville, Kentucky 83. Ildstad ST, Cheerva A, Tollerud D, Bertolone S, Herzig G, Herzig R. Stable mixed chimerism after non- myeloablative transplant for Sickle Cell Disease: normal hematopoiesis dominates over abnormal in mixed chimerism. (Meeting Abstract). American Society of Blood and Marrow Transplantation (ASBMT), Tampa, FL, Feb 11-15, 2009. 84. Zhang Q, Mo Y, Wan R, Chien S, Tollerud DJ. Activation of Endothelial Cells After Exposure to Ambient Ultra Fine particles: The Role of NADPH Oxidase. KY Innovation and Enterpreneurship Conference, Louisville, KY, April 7, 2009, 85. Zhang Q, Mo Y, Ran R, Chien S, Tollerud DJ. Activation of Endothelial Cells After Exposure to Ambient Ultra Fine particles: The Role of NADPH Oxidase. Health Effects Institute (HEI) Annual Conference, Portland, OR, May 3-5, 2009.

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86. Wan R, Mo Y, Tollerud DJ, Zhang Q. Differential Genotoxic Effects of Transition Metal Nanoparticles: The Role of Oxicative Stress. American Thoracic Society International Conference, San Diego, CA, May 15-20, 2009. 87. Mo Y, Wan R, Chien S, Wang J, Tollerud DJ, Zhang Q. Diabetes associated with increased sensitivity of macrophages to particulate matter exposure. American Thoracic Society International Conference, San Diego, CA, May 15-20, 2009. 88. Wan R, Mo Y, Duan X, Yu M, Chien S, Tollerud DJ, Zhang Q. The role of hyposia-inducible factors in MMP-2 and MMP-9 production by human monocytes exposed to nickel nanoparticles. American Thoracic Society International Conference, San Diego, CA, May 15-20, 2009. 89. Mo Y, Ran R, Chien S, Tollerud DJ, Zhang Q. Activation of Endothelial Cells After Exposure to Ambient Ultra Fine particles: The Role of NADPH Oxidase. American Thoracic Society International Conference, San Diego, CA, May 15-20, 2009. 90. Chan MC, Jacobs RR,. Heinbokel J, Tollerud DJ. Building a Dynamic Model Linking Human Exposure to Mercury Emission Regulations: Step One: Risk to susceptible Populations, NIEHS Environmental Health Sciences: Regional Showcase of Fellows, Cincinnati, OH, Sept 18, 2009 91. Tollerud, DJ. Environmental Assessments and Biological Specimen/Biobank Activities. American Public Health Association (APHA) Annual Meeting, Philadelphia, PA, Nov 7-11, 2009. 92. Chan C, Hughes T, Muldoon S, Aldrich T, Rice C, Brion G, Hornung R, Tollerud DJ. Paducah Gaseous Diffusion Plant Mortality Study: Job Title Analysis. American Public Health Association (APHA) Annual Meeting, Philadelphia, PA, Nov 7-11, 2009. 93. R Wan, Y Mo, S Chien, DJ Tollerud, Q Zhang. DNA damage caused by metal nanoparticles: the role of oxidative stress and activation of ATM. American Thoracic Society International Conference, New Orleans, LA,, May 14-19, 2010, 94. Wan R, Mo Y, Chien S, Tollerud DJ, Zhang Q. Combined effects of diesel exhaust particles and high glucose on MMP-2 expression in human monocytes. 50th Annual Meeting of the Society of Toxicology, Washington, DC, March 6-10, 2011. 95. Wan R, Mo Y, Yu M, Chien S, Tollerud, DJ, Zhang Q. Regulation of plasminogen activator inhibitor-1 expression in endothelial cells with exposure to metal nanoparticles. Platform presentation, 49th Annual Meeting of the Society of Toxicology, Salt Lake, UT, March 7-11, 2010. 96. Mo Y, Wan R, Tollerud DJ, Zhang Q. The role of hypoxia-inducible factor in MMP-2 and MMP-9 production by human monocytes exposed to nickel nanoparticles. 49th Annual Meeting of the Society of Toxicology, Salt Lake, UT, March 7-11, 2010. 97. Mo Y, Wan R, Tollerud DJ, Zhang Q. Cigarette smoke extract enhances the effect of ambient ultrafine particles on endothelial cells. 6th Kentucky Innovation and Entrepreneurship Conference, Lexington, KY, P42, April 6, 2010, 98. Wan R, Mo Y, Chien S, Tollerud DJ, Zhang Q. DAN damage caused by metal nanoparticles: the role of oxidative stress and activation of ATM. Am J Respir Crit Care Med 181;2010:A3100; American Thoracic Society (ATS) International Conference; New Orleans, LA, May 14-19, 2010. 99. DeJarnett N, Prabhu S, Bhatnagar A, Tollerud D, Wagner S, Hamzeh I, Chugh A, Zahn M, Troutman A, Meyers J, Becher C, Higdon D, Wyatt B, McCracken J, Riggs D, Abplanalp W, Ciszewski T, Conklin D. Contribution of Air Pollutant Combustion Product Acrolein to Circulating Endothelia Progenitor Cell Level and Cardiovascular Disease Risk, Research Louisville, 3rd Place Student Winner, University of Louisville, Louisville, KY, Oct 2010. 100. Chan MC, Tollerud DJ, Jacobs RR. Building a dynamic model linking human exposure to mercury emission regulations: Step one-Risk to susceptible populations, APHA Annual Meeting, Denver, CO, Nov 2010. 101. Mo Y, Wan R, Chien S, Tollerud DJ, Zhang Q. Cigarette smoke extract enhances the effect of ambient ultrafine particles on endothelial cells. Platform presentation, 50th Annual Meeting of the Society of Toxicology, Washington, DC, March 6-10, 2011.

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102. Leventhal J, Abecassis M, Miller J, Gallon L, Ravindra K, Herzig R, Tollerud DJ, King B, Ildstad ST. Chimerism and Tolerance in HLA-mismatched renal-stem cell transplantation. (Meeting Abstract). International Hand and Composite Tissue Allotransplantation Society (IHCTAS) 2011, Atlanta, GA, April 7- 9, 2011. 103. Leventhal J, Gallon L, Miller J, Mehta J, Zakarija A, Abecassis M, Tollerud D, Herzig R, Ravindra K, Ildstad S. Induction of Donor Specific Tolerance in Recipients of HLA Disparate Living Donor Kidney Allografts by Donor Stem Cell Infusion. (Meeting Abstract). American Transplant Congress, Philadelphia, PA, April 30-May 3, 2011. 104. Mo Y, Wan R, Chien S, Tollerud DJ, Zhang Q. MMP-2 induction in endothelial cells with exposure to urban particulate matter. American Thoracic Society (ATS) International Conference; Denver, Colorado, May 16-20, 2011. 105. Leventhal J, Abecassis M, Miller J, Gallon L, Ravindra K, Tollerud DJ, King BJ, Herzig G, Herzig R, Ildstad ST. Durable chimerism, absence of graft-versus-host disease and the induction of donor specific tolerance in recipients of HLA disparate living donor kidney transplants and therapeutic cell transfer. (Meeting Abstract). 53rd ASH Annual Meeting, San Diego, CA, December 10-13, 2011. 106. Zhang Q, Mo Y, Wan R, Tollerud DJ. Activation of endothelial cells after exposure to ambient ultrafine particles. 2012 HEI Annual Conference, The Drake Hotel, Chicago, IL, April 15-17, 2012, Annual Conference 2012, program and Abstract, page 64. 107. Leventhal J, Abecassis M, Miller J, Gallon L, Herzig R, Tollerud DJ, King BJ, Ildstad ST. A Phase 2 Clinical Trial of Donor Specific Tolerance Induction in Recipients of HLA Disparate Living Donor Kidney Allografts by Donor Stem Cell Infusion. (Meeting Abstract). The American Transplant Congress, Boston, MA, June 2-6, 2012. 108. Feng L, Mo Y, Wan R, Jia Z, Zhang X, Tollerud DJ, Zhang Q. Up-regulation of Gadd45a in Mouse Embryo Fibroblasts with Exposure to Metal Nanoparticles: the Role of Hypoxia Inducible Factor-1α. The 10th China-Japan International Symposium on Health Sciences. Hangzhou, China, June 06-07, 2012. 109. Leventhal J, Abecassis M, Miller J, Gallon L, Herzig R, Tollerud DJ, King B, Ildstad ST. A Phase 2 Clinical Trial of Donor Specific Tolerance Induction in Recipients of HLA Disparate Living Donor Kidney Allografts by Donor Stem Cell Infusion. (Meeting Abstract). The Transplantation Society, Berlin, Germany, July 15-19, 2012. 110. Zhang Q, Wan R, Mo Y, Chien S, Tollerud DJ. DNA Damage Caused by Metal Nanoparticles: Involvement of Oxidative Stress and Activation of ATM. 2012 Research Louisville, Louisville, Sep. 18-21, 2012 111. Leventhal J, Abecassis M, Miller J, Gallon L, Herzig R, Tollerud DJ, King B, Ildstad ST. A phase 2 clinical trial of donor specific tolerance Induction in recipients of HLA disparate living donor kidney allografts by donor stem cell infusion. (Meeting Abstract). The American Society for Reconstructive Transplantation (ASRT) 3rd Biennial Meeting, Chicago, IL, November 15-17, 2012. 112. Leventhal J, Abecassis M, Miller J, Gallon L, Ravindra K, Tollerud DJ, King B, Elliott MJ, Herzig G, Herzig R, Ildstad ST. Update on phase 2 clinical trial to induce tolerance in mismatched living donor renal transplant recipients. (Meeting Abstract). The American Transplant Congress, Seattle, WA, May 18-21, 2013. 113. Leventhal JR, Abecassis M, Miller J, Gallon L, Tollerud DJ, Elliott MJ, Ildstad S. Chimerism and Tolerance without GVHD in Mismatched Recipients of Combined Hematopoietic Stem Cell/Kidney\Transplants: Donor-Specific Hyporeactivity is not a Reliable Biomarker for Tolerance. (Meeting Abstract). 2013 ASH Annual Meeting, New Orleans, LA, December 7-10, 2013. 114. Leventhal JR, Abecassis M, Miller J, Gallon L, Tollerud DJ, Ildstad ST. Update on Phase 2 Clinical Trial to Induce Tolerance in Mismatched Living Donor Renal Transplant Recipients. (Meeting Abstract). 2013 ASH Annual Meeting, New Orleans, LA, December 7-10, 2013.

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Invited Speaker: 1990 Invited Speaker, National Cancer Institute Workshop: Epidemiology of Multiple Myeloma and Black/White Factors, Presentation, “Age and Racial Variations of Immune Function and Hematologic Parameters”, Bethesda, MD, March 1994 Invited Participant: Chair, Scientific Session on “Molecular Epidemiology and Occupational Health” and spoke on “Biomarkers of Response: Immunological, Oxidative Stress and Markers of Tissue Damage” for Agency of Toxic Substances and Disease Registry (ATSDR), CDC, Atlanta, GA 1995 Invited Speaker: “Cytokines in Populations Research: Potential Application in Reproductive Epidemiology”, Magee Women’s Research Institute Seminar, Magee-Women’s Hospital, Pittsburgh, PA. January 1995 Invited Speaker: “Immunotoxicology”, Aspen Environmental Medicine Conference - Conference on Multiple Chemical Sensitivity Issues, Aspen, CO 1996 Invited Speaker: Business Executives Advisory Panel, Occupational Health, Department of the University of Pittsburgh, Beaver Valley 1996 Invited Guest: “Medical Frontiers” Radio Broadcast on WWDB 96.5. Topic of Discussion: “What is New in Environmental and Community Health?” 1996 Invited Speaker: “Cytokines as Immune Biomarkers in Respiratory Epidemiology”, Drexel University, Philadelphia, PA. November 1997 Invited speaker: “Assessing Cancer Risks”, one day course: “Environmental Medicine: Tools for Your Practice”, Department of Public Safety, Bureau of Health, City of Chester in collaboration with Chester City Board of Health: Crozer-Chester Medical Center, Department of Family Medicine, Allegheny University of the Health Sciences and the Agency for Toxic Substance Disease Registry (ATSDR), CDC, Philadelphia, PA 1997 Invited Speaker: “Lead Exposures in the Glass Industry”, two day course: “Management of Environmental Lead Hazards: A Community Challenge” sponsored in part by the US EPA, Commonwealth of Pennsylvania, and the states of Ohio and West Virginia, the regional environmental conference organized through the Allegheny County Health Department 1997 Invited speaker to Western PA Safety Council Conference on “Lead Dangers” 1997 Leader and Speaker of Breakout session: Injury and Violence: Psycho/Social Stresses. Topic presented: “Potential Links Between Violence and Other Health Problems” at AUHS 1997 Research Conference, Valley Forge, PA, October 1997 Invited Speaker: “Assessing Cancer Risks”, one day course: “Environmental Medicine: Tools for Your Practice”, Department of Public Safety, Bureau of Health, City of Chester in collaboration with Chester City Board of Health: Crozer-Chester Medical Center, Department of Family Medicine, Allegheny University of the Health Sciences and the Agency for Toxic Substance Disease Registry (ATSDR), CDC, Philadelphia, PA, April 1997 Invited Speaker: “Lead Exposures in the Glass Industry”, a two day course: “Management of Environmental Lead Hazards: A Community Challenge” sponsored in part by the US EPA, Commonwealth of Pennsylvania, and the states of Ohio and West Virginia. The regional environmental conference organized through the Allegheny County Health Department, June 1997 Leader and Speaker of Breakout session: Injury and Violence: Psycho/Social Stresses. Topic presented: “Potential Links Between Violence and Other Health Problems” at AUHS 1997 Research Conference, King of Prussia, PA, October 1997 Invited Guest: “Medical Frontiers” Radio Broadcast on WWDB 96.5. Topic of discussion: “What is New in the Public Health Arena?”

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1998 Invited Speaker: “Biological Aspects of Cytokines in Indoor Air Quality”, Drexel Univ., Philadelphia, PA, May 1998 Invited Speaker: “Update in Recognizing, Managing and Treating Asthma”, Delaware Valley Pennsylvania Association of Occupational Health, Concordville, PA, October 2000 Invited Speaker: “Recognition and Prevention of Occupational Lung Disease”: A Surveillance Approach. Philadelphia Pennsylvania Association of Occupational Health Nurses, Highland Park, PA, February 2000 Invited Speaker: “Agent Orange: Environmental Science and Policy”. Public Health Grand Rounds, MCP Hahnemann University, Philadelphia, PA 2000 Invited Speaker: “The Intersection of Epidemiology and Policy: The Agent Orange Debate”. Johns Hopkins University School of Public Health and Hygiene, Baltimore, MD 2001 Invited Speaker: "Methodological Considerations in Evaluating the Evidence". National Academy of Sciences, IOM. Immunization Safety Review Committee, Washington, DC, January 2001 Invited Speaker: “A Problem-based Learning Model to Teach ‘Real World’ Environmental and Occupational Health,” Association of Schools of Public Health, Seattle, WA 2001 Invited Speaker: “Vietnam Exposure to Agent Orange" Haverford School, Haverford, PA, March 2001 Invited Speaker: “Agent Orange: Intersection of Science and Policy.” Toxicology Grand Rounds, University of Louisville, Louisville, KY 2002 Invited Speaker: “Agent Orange: Medicine, Science and Policy,” Medical Grand Rounds, University of Louisville, Louisville, KY 2002 Invited Speaker: “The Development and Implementation of a Case-based Approach to Address Bioterrorism: An Educational Strategy,” Association of Schools of Public Health, Pittsburgh, PA 2002 Invited Speaker: “Policy Issues and the IOM Committee Process,” Board on Health Promotion and Disease Prevention, Institute of Medicine, and National Academies of Science 2003 Invited Speaker for panel on Louisville Forum show (Public Television and Public Radio) 2003 Invited Speaker: Environmental Issues show on Insight Television 2004 Invited speaker: “KI Distribution Strategies in the Event of a Radiological Incident,” CDC, March 2005 Invited speaker: NRC Committee report, “Superfund Site Assessment and Remediation in the Coeur d’Alene River Basin,” EPA, Congress and public, Washington, DC and Coeur d’Alene, OD, July 2005 Invited Speaker: “Overview of Emerging Environmental Health Issues Affecting Women and Children’s Health: What Health Care Professionals Should Know,” Louisville, KY, October 2005 Invited Speaker: “Childhood Asthma,” Jefferson County Public Schools, Louisville, KY, November 2006 Invited Speaker: “Health,” Tenth Annual Race and Relations Conference, Louisville, KY, January 2006 Invited Speaker: “Intellectual Approach to the Problems of Megasites.” Academy of Medicine Annual Superfund Basic Research Meeting, New York, NY, January 2006 Invited Speaker: Veterans Administration and AFHS briefings, Washington, DC, February 2006 Invited Speaker: RHAC Report Release and Briefings to Congressional staff, Veterans Affairs and AFHS for National Academies of Science, Institute of Medicine, Washington, DC, February 2006 Invited Speaker: Grand Rounds, University of Washington, Seattle, WA, April 2006 Invited Moderator/Speaker: “Last Child in the Woods,” Louisville Metro Parks Advisory Board, Louisville, KY, November 2006 Invited Speaker: Internal Medicine Update, Norton Health Care, Louisville, KY, December

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2007 Invited Speaker: “Making the Best Use of the Agent Orange Exposure Reconstruction Model,” IOM Committee meeting, Washington, DC, June Invited Speaker: “Emerging Environmental Health Issues Affecting Women and Children’s Health: Metal Toxicity – Arsenic, Lead and Mercury. What Health Care Professionals Should Know-Local Issues.” U of L continuing education seminar, Louisville, KY, August Invited Speaker: WFPL 89.3 FM State of Affairs radio show. Topic: Environmental Genomics and Integrative Biology,” September 2008 Invited Panelist: “Breaking through Barriers Seminar Series,” University of Louisville, School of Medicine, Office of Minority and Rural Affairs, Louisville, KY, February Invited Moderator: “Climate Change,” University of Louisville, School of Public Health and Information Sciences, Louisville, KY, April Invited Speaker: “Environmental Health,” American Lung Association’s 2008 Pulmonary Care Symposium, Louisville, KY, May Invited Speaker: “Environmental Health: Exposures and Respiratory Issues,” Southern Kentucky Area Health Education Center (AHEC) Annual Conference, Mt. Vernon, KY, June 2009 Invited Moderator: “Health Care Transition Forum for Obama-Biden Transition Project,” University of Louisville, Louisville, KY, January Moderator: Center for Environmental Genomics and Integrative Biology, “Translational Biomarkers Workshop,” University of Louisville, Louisville, KY, February Invited Speaker: Zhejiang Academy of Medical Sciences, “Superfund Site Assessment and Remediation in the Coeur d’Alene River Basin,” Zhejiang, China, April Invited Speaker: School of Medicine Grand Rounds, “Pulmonary-Toxicology Lung Disease,” University of Louisville, Louisville, KY, June Invited Speaker: University Health Care Board of Director's Meeting, “National Children’s Study,” University of Louisville, Louisville, KY, June Invited Speaker: Department of Pediatrics Grand Rounds, “National Children’s Study,” Norton’s Hospital, Louisville, KY, September Invited Speaker/Panelist: National Children’s Study: Landmark Epidemiologic Study of the Environment and Child Health. American Public Health Association (APHA) Annual Meeting, Philadelphia, PA, November Invited Speaker: Department of OB/GYN Grand Rounds, “National Children’s Study,” University of Louisville, Louisville, KY, December 2010 Invited Speaker: “National Children’s Study-Jefferson County, KY Center”, OB/GYN Society meeting, Louisville, KY, March Invited Speaker: “Health Effects of Particulate Air Pollution,” Kentucky Environmental Foundation, Environmental Health Webinar/Call-in Series, August Invited Speaker: “National Children’s Study-Jefferson County, KY Center”, School of Public Health Research Incubation, August Invited Panelist: “A Workshop to Obtain Input on the Gulf Long-term Follow-up of Clean-up Workers Study,” National Academy of Sciences, Institute of Medicine, Tampa, FL, September Invited Speaker: “Paducah Gaseous Diffusion Plant Study Results,” Workers and Community meetings, Paducah, KY, September 2011 Media interviews with WHAS-TV, WDRB-TV, WGTK-AM (Joe Elliott Show) and the Courier-Journal regarding the radiation exposure as it relates to the situation in Japan, March

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Presbyterian Union: “Nuclear Power and Radiation Risks–an Environmental Health Perspective”, June Senate and House Committee on Veterans Affairs briefings on report of the Committee on Long-Term Health Consequences of Exposure to Burn Pits in Iraq and Afghanistan – Washington, DC, October Media interviews with Wall street Journal, USA Today, Wired.com, Pittsburgh Tribune-Review, WSJ.com, ABC-TV, November 2013 Research Incubation Meeting, School of Public Health & Information Sciences, Universlty of Louisville, "Clinical Trials using the Facilitating Cell Technology - the Holy Grail of Transplantation", January Medical Grand Rounds, School of Medicine, University of Louisville, “FCRx from Bench to Bedside”, September

RESEARCH

Ongoing Research

03-0553-09 Ildstad (PI) 09/09/13-09/08/16 Regenerex, LLC/Novartis $2,946,670 DC 0.36 calendar months FCRx Manufacturing The goal of this project is to manufacture a proprietary bone marrow product termed “FCRx”. The subcontract to Regenerex, LLC is for personnel salaries and operating expenses to administer the program, conduct the bone marrow processing activities (training, validation, and clinical trials), conduct immune monitoring of the transplanted subjects, and facilitate the regulatory components of the clinical trials. Role: Co-Investigator

03-0553-09 Ildstad (PI) 09/09/13-09/08/16 Regenerex, LLC/Novartis $5,254,167 DC 0.36 calendar months Mechanism of the Facilitating Cell The goal of this project is to develop an improved understanding of the mechanism of the Facilitating Cell (FC). FC are a rare population of cells found in the bone marrow that enable the long-term, durable engraftment of hematopoietic stem cells across genetic barriers. Under this award, studies will be undertaken to identify the role of the FC in the induction of regulatory cells, develop improved recipient conditioning regimes, establish protocols that will allow engraftment in high PRA settings, and determine gene pathways critical for FC function. Role: Co-Investigator

03-0553-09 Ildstad (PI) 09/09/13-09/08/16 Regenerex, LLC/Novartis $551,148 DC 0.12 calendar months Processing supplies for FCRx Processing and Monitoring The goal of this project is to define the mechanism of facilitating cell function and continue FCRx clinical trials.

T35 ES 014559-01 Prough (PI) 04/01/06-03/30/16 (renewed 2012) NIEHS/NIH 0.00 calendar months Summer Environmental Health Sciences Training Program Summer research training for medical students in the area of basic and clinical environmental health. Role: Mentor

HSRB12-DSHEFS-04XP Anderson (PI) 11/26/12-03/31/15 CDC/NIOSH Study of Cause-Specific Mortality in Combined Cohort of Uranium Enrichment Workers Project will examine the patterns of cause-specific mortality and incidence of cancer and end-stage renal disease in pooled cohort of workers employed at three U.S. uranium enrichment plants (see R01 OH007650). Role: Consultant

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2R42DK074331-03A2 Ildstad (PI) 09/15/11-06/30/14 Regenerex, LLC/NIH $507,703 DC 0.48 calendar months Induction of Donor Tolerance in Renal Transplants (Phase II) Induce tolerance following kidney transplantation by producing an hematopoietic stem cell transplant graft that will achieve engraftment of HLA mismatched donor stem cells in nonmyeloablatively conditioned transplant recipients without causing significant GVHD. Role: Co-Investigator of subcontract

T32 ES11564 Hein (PI) 07/01/04-06/30/14 (renewed 2009) NIEHS/NIH $662,160 Total DC 0.00 calendar months Molecular Epidemiology of Environmental/Occupational Disease This training grant is jointly held between the Department of Pharmacology & Toxicology and Biochemistry & Molecular Biology to support four students per year. Role: Mentor and Internal Advisory Board

Completed Research

NCS-08-21E (RFP) Tollerud (PI) 09/29/08-09/28/13 NIH-NICHD $11,431,492 TC 4.8 calendar months National Children’s Study – East Study Center, Jefferson County, KY This Initiative will provide critical new information regarding environmental influences on children’s health and develop secondary and tertiary sampling units within Jefferson County over a 25-year period. The largest government-funded long-term study of environmental and genetic effects on children’s health to be conducted in the United States.

W81XWH-10-1-0688 Ildstad (PI) 08/18/10-08/17/13 NFCTR/Dept of Defense, Off of Army Res $1,141,221 TC 0.12 calendar months Tolerance Induction for Tissue and Organ Transplants Safely establish mixed chimerism and induce tolerance using facilitating cell (FC)-based therapeutic approaches and nonmyeloablative conditioning. Role: Co-Investigator of subcontract

2R42 HL074579 ldstad (PI) 09/20/08-08/31/12 Regenerex, C/NIH (NHLBI) $579,380 TC 0.36 calendar months Stem Cell Graft Engineering to Treat Sickle Cell Disease (Phase II) Project is to develop an approach to engineer a bone marrow graft to avoid the major complications of HSCT: graft-versus-host reactivity (GVHD); graft failure; and the need for perfect matching. Our approach is superior to current therapies because it involves a proprietary process that enriches for patented facilitating cells (FC) and stem cells but removes GVHD-producing cells. Role: Co-Investigator

1R01AG024040-01A2 Litvan (PI) 07/01/06–06/30/11 Institute for Aging $628,868 TC 0.24 calendar months Genetic and Environmental Risk Factors for PSP The goals of this study are to determine if there is an association between progressive supranuclear palsy (PSP) and the H1/H1 genotype, specific H1 sub-haplotypes, alpha-synuclein polymorphisms or parkin gene deficits, or if there are gene-gene interactions; if there is an association between PSP occupational and/or environmental chemical exposures functionally or structurally similar to rotenone/acetogenins; and if hypertension or traumatic brain injury prior to symptom-onset is associated with PSP. Role: Co-Investigator

1P30ES014443-01A1 K. Ramos (PI) 06/4/07-03/31/11 NIH/NIEHS $3,000,000 DC Center for Environmental Genomics and Integrative Biology The goal of this grant is to support outstanding basic and translational investigations into the etiology of environmental disease and the development of new approaches to manage these conditions. The Integrated Health Sciences Facility Core’s central goal is to provide Center investigators with services and resources that will facilitate the translation of basic research finding into clinical or public health applications. The Community

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Outreach and Education Core’s primary goal will be to educate residents in the Louisville Metropolitan Area (9 counties in Kentucky and 4 in Indiana) on the importance of interactions between genes, environment, culture, and disease focusing on Hispanic communities. Role: Director IHSF Core; Co-investigator on other cores

R01 OH007650 Tollerud (PI) 07/01/02-06/30/09 NIOSH $2,900,041 DC 0.24 calendar months Health Effects of Occupational Exposures in PGDP Workers Study is to carry out a feasibility study and pilot study to evaluate the health impact of occupational exposures on workers at the Paducah, KY Gaseous Diffusion Plant (PGDP) to determine if workers have a mortality rate which exceeds that of the general population, particularly for cancer. This study will be an important contribution to our knowledge about the health of a key occupational cohort of workers that contain 6859 individual names from 1953-2003.

T01 HP01397 McKinney (PI) 09/01/03-08/31/08 HRSA $2,536,387 DC 0.24 calendar months Preparing Health Professions to Respond to Bioterrorism Project is to provide comprehensive continuing training and education programs in bioterrorism preparedness for healthcare professionals throughout Kentucky and the surrounding region. Role: Investigator

(KSTC) LLC/Phase I Tollerud (PI) 05/01/07-06/30/08 Kentucky SBIR/STTR Matching Funds $50,001 TC 0.24 calendar months Tolerance Induction in Renal Transplants Project is to induce donor specific tolerance in five kidney patients.

1 R41 DK074331 Tollerud (PI) 6/03/05-11/30/07 LLC/NIH (NIDDK), STTR Induction of Donor Tolerance in Renal Transplants Project is to test a cell dosing algorithm of processed donor marrow or mpbsc to induce donor specific tolerance in five kidney patients.

RG-872-N Zhang (PI) 07/01/05–12/30/06 American Lung Association $1,625,000 DC Endothelial Generation of Reactive Oxygen Species in Lung Exposure to Ultra Fine Particles The goal of this proposal to investigate the substantial and consistent epidemiological evidence for an association between environmental particles and morbidity, as well as mortality of cardiopulmonary diseases. Role: Co-Investigator

CIF-213-RD Ildstad (PI) 04/01/04-03/31/06 Innovation Group of KSTC Tolerance Induction in Organ Transplant Recipients This grant supports the clinical non-reimbursable costs for cardiac and renal allograft tolerance phase I protocol. Role: Co-Investigator

R01 HL64978 Ildstad (PI) 08/15/99-07/31/05 NIH/HL Mixed Chimerism to Treat Sickle Cell The goal of this project is to apply Bone Marrow Transplantation to treat Sickle Cell disease, yet avoid morbidity and mortality of lethal conditioning, graft-versus-host disease, and lack of suitably matched donors. Role: Co-Investigator

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R01 OH03419-05A1 NIOSH Peele (PI) 07/01/01-09/29/04 Work Related Motor Vehicle Crashes: Reducing the Burden The goal of this project is to comprehensively analyze the nature and causes of occupational motor vehicle crashes involving City vehicles and to develop a risk factor model which accounts for morbidity and economic burden of these events. Role: Consortium PI

RO1 OH 04020-01 NIOSH Tollerud (PI) 1999-2003 Claims-Based Surveillance to Identify Injury Precursors

Synergy, Drexel University Tollerud (PI) 2001-2002 Speciation and Bioavailability of Heavy Metals Associated with Airborne Particulate Matter

EPRI Tollerud (Co-PI) 1997-2000 Ambient Particulates, Allergens and Asthma

NIOSH Tollerud (PI) 1996-2000 Analysis of Capitated Payments in Worker’s Compensation

NIH Tollerud (PI) 1994-1996 Cord Blood Cytokines as Predictors of Childhood Respiratory Disease: Analysis by Chemiluminescence ELIZA

Univ.of Pittsburgh Tollerud (PI) 1992-1996 Training of Physicians in Occupational Medicine

BRSG Tollerud (PI) 1991 Chemiluminescence Assays for Detection of Cytokines

American Cancer Society Tollerud (PI) 1991 Development of Sensitive ELISA Assay for Colony Stimulating Factors

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