Drugs, bytes and Standards: The Future of Radiology

11th Biennial International Symposium of the International Society for Strategic Studies in Radiology IS3R 2015 /The Netherlands August 27–29, 2015 Scientific Program 1 Imprint Vienna, July 2015 © IS3R, www.is3r.org Coordination: Monika Hierath, Katharina Krischak Design: Sonja Huber, www.diehuber.at Print2 office: druck.at Table of Contents

Letter from the President 4 Letter from the Program Chairs 5 About the IS3R 6 IS3R Organization 7 IS3R Gold Medal 8 Program Overview 10 Scientific Program Schedule 11 Venue 15 Practical Information 16 Corporate Members 17 List of Participants 19

3 Letter from the President

Dear Fellow Members, Colleagues, and Friends,

On behalf of the Executive Board of the In- The program of this year’s symposium is outstanding. I am extremely grateful to Ralph ternational Society for Strategic Studies in Weissleder and all the members of the Program Committee for including truly timely and Radiology, it is my great pleasure to wel- stimulating topics. The large number of panel discussions will enable interactive exchange of come you to the 11th Biennial International opinions between our distinguished members and our industrial partners. It is this exchange Symposium of our Society, August 27–29, to which we are particularly looking forward as it brings a very special flavor to our meetings: 2015, in Amsterdam, the Netherlands. I am the interaction between professionals and companies involved in the field of imaging with extremely pleased that the Executive Board the intention to improve the health and well-being of our patients. On behalf of our entire of IS3R has chosen the capital of my country society, I would like to thank our corporate members for their support and active participa- as the venue of our meeting as I feel that this tion. vibrant city with its international flair com- bining history and tradition with extreme In addition to the program-related interaction, I hope that participants will benefit from tolerance and unconventional thinking fits the possibility to establish new and intensify old relationships, to start new and expand old perfectly with the aims of our Society and friendships, and to experience stimulating conversations in a relaxed environment. But I also with the atmosphere of our meetings. hope that all attendees will take advantage of Dutch hospitality and of the social events that offer a small taste of the history of Amsterdam as well as providing some food for thought. During the past two years the IS3R has implemented a number of new activities: an “Interim Meeting” was held in December 2014 in Chicago revisiting the developments in our field. This may be the start of an increasingly intense dialogue over the coming years. At the 2015 International Symposium, we, for the first time, welcome a group of young leaders, who we hope will boldly and resolutely guide our profession into a challenging but very promis- ing future. I hope that the information received in our meetings and the contacts with our members and partners from industry will spur their careers so that they may indeed play a meaningful role during the years to come.

As my tenure as President of the IS3R is coming to an end, I would like to express my gratitude to all members of the Executive Board for their support and hard work. A special word of thanks goes to Hedi Hricak, our Past President, on whose wisdom I could always rely with trust and confidence. I would like to congratulate Jonathan Lewin, our incoming President, and wish him a successful term. I am convinced that under his expert and dedicated guidance the IS3R will continue to flourish as a unique platform for high-level strategic exchange in Medical Imaging.

Best wishes,

Gabriel Krestin, MD, PhD IS3R President

4 Letter from the Program Chairs

Dear Colleagues, on behalf of the Program Committee for our This year’s symposium will focus on three distinct areas: imaging and molecular therapeutics, 11th Biennial International Symposium held information technology and standards in radiology. These areas were chosen by the Program this week in Amsterdam, the Netherlands, Committee as they will likely change our specialty over the years to come. Session 1 focuses August 27–29, 2015, it is our pleasure to on “imaging in the molecular era” where molecular diagnostics and targeted therapeutics present the final program and details for the are ever more pervasive. The session also encompasses discussions on unique growth oppor- meeting. We anticipate a very thought-pro- tunities and barriers to commercialization. Session 2 focuses on clinical applications of PET voking meeting as well as lively discussion imaging technologies and their different challenges in penetrating the market while session from our usual gathering of academic, clini- 3 addresses changes and opportunities in healthcare informatics, clinical decision support cal, and industrial leaders. and next generation information technologies in radiology. Finally, session 4 focuses on di- verse restructuring efforts in and affecting radiology as well as the need for more rigorous standards. We hope that you are as excited by these topics as we are as we look forward to engaging discussions.

Two keynote lectures will be presented by distinguished experts to lay the foundation for continued conversations on the future of healthcare, global changes and challenges and scientific opportunities. A hallmark of our meetings is time for panels and interactive discus- sions to facilitate the exchange of ideas. We have tailored the program to ensure that there is sufficient time after each session for these discussions. As in the past, we will prepare a summary of the meeting outcomes which will be distributed to our members.

We would like to thank the entire Program Committee for its tireless efforts in organizing this year’s meeting. Together, we would also like to thank the IS3R office staff and the rest of the IS3R board for their support in preparing for the meeting. Last but not least, we would like to thank all the invited speakers, moderators, and panelists for their invaluable contributions. It is their input that will hopefully make this meeting a huge success. We look forward to welcoming you in Amsterdam.

With best regards,

Ralph Weissleder, MD, PhD gabriel Krestin, MD, PhD hedvig Hricak, MD, PhD Chair of the President and local host of Co-Chair of the Program Committee the Program Committee Program Committee

5 ABOUT THE IS3R

Mission of the IS3R Committees

The International Society for Strategic Studies in Radiology is a non-political, not-for-profit PUBLICATIONs COMMITTEE organization whose purpose is to define and investigate strategic, scientific and economic Chair issues of global importance to the field of radiology. Christian Herold (Vienna/AT) Members By forming a partnership between academia and industry, the Society seeks to anticipate Byung Ihn Choi (Seoul/KR) national and global developments in radiology and allied fields, define areas of common in- Adrian K. Dixon (Cambridge/UK) terest to both partners, and encourage cooperation. It aims to communicate important issues Hedvig Hricak (New York/US) to radiologists, physicians in other medical fields, industry and governments, and to influence Gabriel P. Krestin (Rotterdam/NL) healthcare management and the flow of financial and human resources into the scientific and Jonathan S. Lewin (Baltimore/US) strategic fields most likely to advance biomedical imaging and patient care. Stefan Schönberg (Mannheim/DE) James H. Thrall (Boston/US)

MEMBERSHIP & NOMINATING COMMITTEE Chair IS3R Executive Board Maximilian F. Reiser (Munich/DE) Co-Chair President By-Laws & Rules Committee Herbert Y. Kressel (Boston/US) Gabriel P. Krestin (Rotterdam/NL) Chair: James Thrall (Boston/US) Members Boris Brkljacic (Zagreb/HR) Past President Corporate Advisory BOARD Bruce Hillman (Charlottesville/US) Hedvig Hricak (New York/US) Chair: William G. Bradley (San Diego/US) Pek-Lan Khong (Pokfulam Hong Kong/CN) Norbert J. Pelc (Stanford/US) Founding President Program Committee Mitchell D. Schnall (Philadelphia/US) Alexander R. Margulis (New York/US) Chair: Ralph Weissleder (Boston/US) Valentin Sinitsyn (Moscow/RU)

President-Elect COMPLIANCE COMMITTEE BY-LAWS & RULES COMMITTEE Jonathan S. Lewin (Baltimore/US) Chair: Guy Frija (Paris/FR) Chair James Thrall (Boston/US) Vice President AWARDS AND HONOURS COMMITTEE Co-Chair Xiaoyuan Feng (Shanghai/CN) Chair: Hedvig Hricak (New York/US) Stefan Schönberg (Mannheim/DE) Members Treasurer YOUNG LEADERS CLUB COMMITTEE Dieter Enzmann (Los Angeles/US) Luis Donoso (Barcelona/ES) Chair: Carlo Catalano (Rome/IT) Moshe Graif (Tel Aviv/IL) Sachio Kuribayashi (Tokyo/JP) Secretary EXECUTIVE BOARD Members at Large András Palkó (Szeged/HU) Norman J. Beauchamp (Washington/US) Ronald Arenson (San Francisco/US) Boris Brkljacic (Zagreb/HR) CORPORATE ADVISORY BOARD Publications Committee Giovanni Cerri (Sao Paulo/BR) Chair Chair: Christian J. Herold (Vienna/AT) Sanjiv S. Gambhir (Stanford/US) William G. Bradley (San Diego/US) Stefan Schönberg (Mannheim/DE) Co-Chair Membership & Nominating Committee Kazuro Sugimura (Kobe/JP) Bernd K. Hamm (Berlin/DE) Chair: Maximilian Reiser (Munich/DE) Members Norman J. Beauchamp (Seattle/US) James A. Brink (Boston/US)

6 IS3R Organization

Administration

Byung Ihn Choi (Seoul/KR) AWARDS AND HONOURS COMMITTEE IS3R – European Office Luis Donoso (Barcelona/ES) Chair Society and Symposium Secretariat Xiaoyuan Feng (Shanghai/CN) Hedvig Hricak (New York/US) Monika Hierath & Katharina Krischak Christian J. Herold (Vienna/AT) Members Neutorgasse 9/2, 1010 Vienna, AUSTRIA Hedvig Hricak (New York/US) Adrian K. Dixon (Cambridge/UK) Phone: +43-1-533-4064-20 Valerie Jackson (Indianapolis/US) Philippe Grenier (Paris/FR) Fax: +43-1-535-7041 Gabriel P. Krestin (Rotterdam/NL) Gabriel P. Krestin (Rotterdam/NL) E-mail: [email protected] Jonathan S. Lewin (Baltimore/US) Barbara McNeil (Boston/US) Carolyn C. Meltzer (Atlanta/US) IS3R – US Office Maximilian F. Reiser (Munich/DE) YOUNG LEADERS CLUB COMMITTEE Society Secretariat Chair Pamela F. Mechler PROGRAM COMMITTEE Carlo Catalano (Rome/IT) 1891 Preston White Drive Chair Co-Chair Reston, VA 20191, USA Ralph Weissleder (Boston/US) Hedvig Hricak (New York/US) Phone: +1-703-716-7545 Co-Chairs Members Fax: +1-703-716-4487 Hedvig Hricak (New York/US) N. Reed Dunnick (Ann Arbor/US) E-mail: [email protected] Gabriel P. Krestin (Rotterdam/NL) Xiaoyuan Feng (Shanghai/CN) Members Christian J. Herold (Vienna/AT) www.is3r.org James A. Brink (Boston/US) Herbert Y. Kressel (Boston/US) William R. Brody (La Jolla/US) Gabriel P. Krestin (Rotterdam/NL) R. Nick Bryan (Philadelphia/US) Maximilian F. Reiser (Munich/DE) Philippe Grenier (Paris/FR) Thomas M. Grist (Madison/US) Christian J. Herold (Vienna/AT) Zhengyu Jin (Beijing/CN) Jonathan S. Lewin (Baltimore/US) Maximilian F. Reiser (Munich/DE) Hans Ringertz (Linköping/SE) Stefan Schönberg (Mannheim/DE) Markus Schwaiger (Munich/DE) James H. Thrall (Boston/US) Elias Zerhouni (Baltimore/US)

COMPLIANCE COMMITTEE Chair Guy Frija (Paris/FR) Co-Chair Kazuro Sugimura (Kobe/JP) Members Ronald Arenson (San Francisco/US) Lorenzo Bonomo (Rome/IT) Bernd K. Hamm (Berlin/DE) Hiroshi Honda (Fukuoka/JP) Jonathan S. Lewin (Baltimore/US)

7 IS3R GOLD MEDAL

Hans G. Ringertz, MD, PhD, F.F.R.RCSI, FRCR(Hon), FACR(Hon), FHKCR(Hon)

Dr. Hans G. Ringertz will be awarded the Dr. Ringertz began his studies in 1958 in biophysics research; earned his M.D. in 1964 and 2015 IS3R Gold Medal at the 11th Biennial his PhD in biophysics in 1969. He held the position of Associate Professor in biophysics from Symposium. 1969 to 1973 and in diagnostic radiology from 1973 to 1983. Dr. Ringertz served as Professor of radiology at the Karolinska Institute from 1984 to 2006 before being named Professor Emeritus in 2006; a position he continues to hold. During his tenure at Karolinska Institute he held the following hospital positions: Assistant Head of Paediatric Radiology at Karolinska 1973-77; Head of Radiology, Sachs Paediatric Hospital Stockholm 1977-83; Chairman, Diag- nostic Radiology, Huddinge University Hospital 1984-87 and Karolinska Hospital 1987-2006. From 2006 to 2013 he was Professor and Chairman of the Board for the Center for Medical Imaging Science and Visualization, Linkoping University. Since 2013 he has served as a Con- sulting Professor at the Department of Radiology, Stanford University.

Dr. Ringertz has also been recognized as a Fellow in Pediatric Cardiac Imaging at UCSF in 1975; a visiting Professor responsible for pediatric MRI at UCSF 1983-84; a visiting Professor at Stanford University 2004-2012; co-director of the Strategic Center for Biomedical Imaging at Stanford 2007-2010; and Adjunct Professor of Radiology at UCSF 1984-2009 and Michi- gan State since 1991.

Dr. Ringertz is the author of 240 scientific articles and six books. He served as a permanent member of the Nobel Assembly for Physiology and Medicine from 1986 to 2006 and held the positions of President Elect and President in 2002 and 2003. He was a Trustee of the Nobel Foundation from 2002 to 2007. He was a member of the International Commission on Ra- diological Protection, committee 3, Medicine from 1992 to 2013. Dr. Ringertz is an honorary member of 15 national and regional radiological societies, including the Society for Pediatric Radiology and the European Society of Paediatric Radiology, and an honorary fellow of four Colleges. He has been awarded Gold Medals from Tokyo University, Japan, the European Society of Radiology, and the Asian Oceanian Society of Radiology.

Dr. Ringertz held the position of President for the International Congress of Paediatric Ra- diology 1991; the Swedish Society of Medical Radiology 1995-97; the European Congress of Radiology 1995-97; the European Association of Radiology 1997-99; the Swedish Union of Radiologists 1999-2005; and the International Society for Strategic Studies in Radiology 1999-2003. He served the International Society of Radiology as Treasurer 2000-2005; Presi- dent Elect 2006-2008; President 2008-2010; and Past President 2010-2012.

8 IS3R GOLD MEDAL

Hans G. Ringertz, MD, PhD, F.F.R.RCSI, FRCR(Hon), FACR(Hon), FHKCR(Hon) James H. Thrall, MD, FACR

Dr. James H. Thrall will be awarded the 2015 Dr. Thrall served as Chairman of the Department of Radiology, Massachusetts General Hos- IS3R Gold Medal at the 11th Biennial Sympo- pital (MGH) and as the Juan M. Taveras Professor of Radiology at Harvard Medical School sium. (HMS) from 1988 until 2013. He continues his service at MGH and HMS as Chairman Emeri- tus and as the Distinguished Taveras Professor of Radiology.

Dr. Thrall received his M.D. degree from the University of Michigan in 1968 and trained in Radiology and Nuclear Medicine at the Walter Reed Army Medical Center, Washington, D.C. where he also held the position of Assistant Chief of Nuclear Medicine for two years before returning to the University of Michigan in 1975 as an Assistant Professor. He was promoted to Professor of Internal Medicine and Radiology in 1981. He joined the staff of the Henry Ford Hospital as Chairman of Radiology from 1983 until 1988.

Dr. Thrall has held the positions of President, American Roentgen Ray Society and Chairman, Board of Chancellors and President, American College of Radiology (ACR). He served on the Board of Trustees of the Research and Education Foundation of the Radiological Society of North America, the Board of Directors of the Academy of Radiology Research, the Execu- tive Council of the American Roentgen Ray Society, the Board of Trustees of the Society of Nuclear Medicine, the Board of Councilors of the Society of Chiefs of Academic Radiology Departments and the Board of Chancellors of the ACR.

Dr. Thrall is an elected member of the Institute of Medicine (IOM) of the National Acade- mies of the United States. He has served on the Advisory Committee to the Director of the National Institutes of Health (NIH) and the National Advisory Council of the NIBIB. He is a Fellow of the ACR and has received the Gold Medals of the American Roentgen Ray Society, the Radiological Society of North America, the Association of University Radiologists and the American College of Radiology.

Dr. Thrall holds the positions of Chairman of the Board of Directors for WorldCare Limited and Mobile Aspects Incorporated.

Internationally, Dr. Thrall has served on the Board of Directors of the International Society of Radiology and currently serves on the Executive Board of the International Society for Strate- gic Studies in Radiology.

Dr. Thrall is an Honorary Member of the French Society of Radiology and the European Soci- ety of Radiology and an Honorary Fellow of the Royal College of Radiologists of the United Kingdom. He received the Beclère Medal from the International Society of Radiology.

Dr. Thrall is an author of over 350 scientific publications, perspectives and reviews and is the founder and Editor of the Requisites in Radiology textbook series.

9 PROGRAM OVERVIEW

Thursday, August 27* Friday, August 28* Saturday, August 29*

From Breakfast From Breakfast From Breakfast 07:00 (Admiralty) 07:00 (Admiralty) 07:00 (Admiralty)

07:30 Registration 08:30 Session III: Healthcare IT 08:30 Session IV (con.): 08:30 Welcome and Opening Remarks Standards and Changes in 10:30 Break Radiology 09:00 Keynote Address 1 11: 00 P anel Discussion: Next gen 10:30 Break 09:45 Session I: Molecular informatics and clinical Therapies and Imaging decision support 11: 00 P anel Discussion: Standardization of imaging 10:25 Break 12:00 l unch biomarkers across different (Admiralty) vendors 10:55 S ession I (con.): Molecular Therapies and Imaging 13:00 Panel Discussion (con.): Next 12:30 Summary and Closing gen informatics and clinical 11:55 l unch decision support (Admiralty) 14:00 Keynote Address 2 13:00 Farewell Lunch 13:00 Panel Discussion: Companion (Admiralty) imaging diagnostics (CID) 14:45 Break

14:00 Break 15:15 S ession IV: Standards and Changes in Radiology 14:30 S ession II: PET Technologies, MRI-PET P anel Discussion: Changing times of Academic/industry 16:00 Adjourn relationships

16:45 Panel Discussion: 16:00 IS3R General Assembly Non-physician support (members only) 17:45 Adjourn

19:00 Social Event at Rosarium 19:30 Social Event at National Maritime Museum

*All sessions take place in the Council Chamber.

10 SCIENTIFIC PROGRAM Schedule

Thursday, August 27

OPENING SESSION 13:00 PANEL DISCUSSION: Companion SESSION II: PET TECHNOLOGIES, imaging diagnostics (CID) MRI-PET 08:30 Opening Remarks and Welcome Chairs: O. Clément, B. Hillman Chairs: O. Ratib, C. Meltzer, P.-L. Khong 09:00 Keynote address: The future of health-care from company a. Is there a business for CID 14:30 What are the niches for MRI-PET? perspective and how do we get them g. von Schulthess F. van Houten reimbursed? 14:45 What are the European challenges J. Debatin for PET (incl. regulatory hurdles for Session I: MOLECULAR THERAPIES b. CID development from a pharma new tracers)? AND IMAGING company perspective C. Claussen Chairs: B. Hamm, H. Honda M. Mintun 15:00 P ET neuroincubator model – c. CID development from a enabling the field by making PET 09:45 The growing field of theranostics diagnostics company perspective tracers available through a self- and companion imaging diagnostics A. Spinazzi sustaining initiative m. Schwaiger d. CID development from a g. Brophy 10:05 Precision Health: The Baseline Study diagnostics company perspective 15:15 Fifteen years after the introduction S. Gambhir E. Lancelot of PET/CT: the Siemens experience e. CID development from an W. Märzendorfer 10:25 Break equipment manufacturer 15:30 Fifteen years after the introduction perspective of PET/CT: the Toshiba experience 10:55 Interventional approaches for R. Mather R. Mather molecular testing f. NIH perspectives 15:45 Fifteen years after the introduction R. Weissleder R. Pettigrew of PET/CT: the Phillips experience 11:15 Imaging in drug development: h. Pien patient selection or efficacy 14:00 Break H. Hricak 16:00 Adjourn 11:35 Imaging and in vitro biomarkers: challenges and opportunities for integrated diagnostics (academic 16:00 IS3R General Assembly perspective) (members only) g. Krestin

11:55 lunch 19:00 Social Event at Rosarium Meeting point for bus transport in hotel lobby at 18:15

11 SCIENTIFIC PROGRAM Schedule

Friday, August 28

SESSION III: HEALTHCARE IT 13:00 3. What are the challenges g. New models (academic Chairs: M. Reiser, P. Aspelin, developing/implementing Next perspective Brazil) R. Garcia-Monaco Generation IT? G. Cerri W. Kalender, M. Graif h. New models (academic 08:30 Update on clinical decision support perspective Asia) J. Brink 4. Digital connectivity and big data Z. Jin, X. Feng, K. Sugimura 08.50 H ow will “big data” affect radiology for standardised high quality (research/analytics)? outcomes and efficient care 16:45 PANEL DISCUSSION 2: R. Arenson delivery Non-physician support 09:10 What does image mining offer? D. Moulavasilis Chairs: L. Bonomo, B. Choi, Why should we care? H. Gharbi T. Grist 14.00 Key note address: Phenotyping 09:30 How will Apple and Google health- of genetic disorders using in a. Who/what are the drivers care entries change our space? vivo imaging (expand access and decrease J. Lewin J. Penninger costs) 09:50 Opportunities for business analytics S. Golding software 14:45 Break b. Can computers be a radiologist’s D. Enzmann assistant (clinical decision support 10:10 Large scale, vendor neutral solutions SESSION IV: STANDARDS AND software for neuroradiology; m. Prokop CHANGES IN RADIOLOGY a start-up perspective)? R. Bryan 10:30 Break 15:15 PAN EL DISCUSSION 1: Changing c. Outsourcing to other countries times of Academic/industry A. Dixon 11: 00 PAN EL DISCUSSION: Next gen relationships d. Physician extenders informatics and clinical Chairs: N. Dunnick, B. Brkljacic, K. Soyebi decision support S. Ternovoy e. Back to Basics: IQ, Apps and Chairs: V. Jackson, S. Schönberg Automation a. How are the relationships Y. Wedmid 1. What’s on the horizon beyond changing? PACS? P. Grenier 17:45 Adjourn a. Cloud Imaging enabling b. What has worked and what breakthrough analytics and hasn‘t? boundaryless collaboration N. Pelc J. De Witte c. New models (industry 19:30 SOCIAL EVENT at National Maritime b. New IT developments perspective: Siemens) Museum G. Sorensen B. Montag Boat will depart from Sofitel Legend d. New models (industry The Grand at 18:30 2. What are the opportunities and perspective: Philips) barriers to broad adoption of D. Olego clinical decision support? e. New models (academic S. Seltzer, L. Donoso, G. Frija perspective Europe) C. Catalano 12:00 lunch f. New models (academic perspective Russia) V. Sinitsyn

12 SCIENTIFIC PROGRAM Schedule

Saturday, August 29

SESSION IV (con.): STANDARDS AND 11: 00 PAN EL DISCUSSION 3: CHANGES IN RADIOLOGY Standardization of imaging Chairs: C. Herold, S. Baum biomarkers across different vendors 08:30 Partnering and interdisciplinary Chairs: J. Dai, D. Le Bihan, interactions in radiology M. Fuchsjäger (departments vs. service lines/centers) and the importance of a. FDA requirements for multidisciplinary conferences quantitative biomarker approval W. Bradley D. Sullivan 08:50 Conflict of interest and compliance. b. How do we implement How does it work with increasing standardized biomarkers pressure to enter academic/private M. Schnall sector relationships? c. Technology pre-requisites for H. Kressel Imaging Biomarkers: State- 09:10 external factors in finance affecting of-the-art today andfuture radiology utilization directions B. McNeil B. Ohnesorge 09:30 ACOs in the US (i.e. population health management); Imaging 3.0 12.30 SUMMARY and CLOSING (value vs. volume). H. Ringertz, R. Weissleder, G. J. Thrall Krestin 09:50 Companies buying hospitals and practices: what is happening in Europe? A. Palkó 13:00 FAREWELL LUNCH 10:10 Rising cost of imaging and equipment. How to control costs g. Rubin

10:30 Break

13 14 VENUE

Hotel Information

Sofitel Legend The Grand 197 1012 EX Amsterdam, Netherlands Phone: (+31)20 / 5553111

Fax: (+31)20/5553222

Email: [email protected]

Geldersekade

Web: www.sofitel-legend-thegrand.com Anne Frank‘s House

Oosterdok

Sofitel Legend The Grand Amsterdam is a Oudezijds Voorburgwal

Waalseilandsgracht

five-star hotel in the heart of the city of- Royal Palace

fering a unique historical ambiance. From Sofitel Legend The Grand

th a 15 -century convent to royal lodgings to Oude Schans Dutch Admiralty headquarters to the city Kloveniersburgwal hall of Amsterdam, the hotel boasts a rich history. The venue is within walking distance

of Amsterdam’s major landmarks, including the Van Gogh Museum, the Royal Palace, binnenAmstel

Anne Frank’s House, and the new Hermit - age Amsterdam. Hermitage Amsterdam binnenAmstel

Amstel

Van Gogh Museum

15 PRACTICAL INFORMATION

Practical Information

Certificate of Attendance travel insurance are up-to-date and valid for sium hours from Thursday to Saturday. They Participants who would like to receive a use in Amsterdam. will assist you with local information for certificate certifying their attendance at sightseeing in Amsterdam, booking optio- the symposium are encouraged to request Meals nal tours, or any questions regarding your one from the IS3R Office per email after the Buffet breakfast is included at the Sofitel accommodations. The registration desk is event. Legend The Grand in the Admiralty Room. located outside the main lecture hall. Business lunch buffet and coffee breaks for Credit Cards/Currency Exchange all participants will be provided. Thank you Smoking Policy The hotel reception provides currency ex- for your understanding that the IS3R does The symposium meeting sessions are non- change up to $500. The closest exchange not provide lunch and coffee breaks for ac- smoking. However, smoking is permitted in office is located at Amsterdam Central Sta- companying persons. the hotel’s cigar lounge. tion (10 min walk). The nearest ATM can be found in (2 min walk). Major Official Language Speakers‘ Desk Credit Cards are accepted. English (no translation of the meeting will be Speakers are kindly requested to upload provided). their presentation at the Speakers’ Desk lo- Insurance cated in the Bourgomaster Chamber close Neither the IS3R nor the symposium organi- Recording to the main lecture hall at least 90 minutes zers can accept liability for personal injury, or Audio or video recording any part of the before the session starts. At the Speakers‘ loss/damage to property, personal or other- symposium without prior express permission Desk, participants are moreover asked to wise, belonging to meeting participants or is prohibited. complete a conflict of interest form and sign accompanying persons, either during or as a presentation release consent form for ar- a result of the symposium or during all tours Registration chiving purposes and use in the protected or their stay in Amsterdam. Participants and Staff at the symposium registration desk will members area in pdf format. accompanying persons should ensure that be available on Wednesday evening from their own personal health, accident and/or 15:00-19:00, as well as during the sympo-

Social Evening Events

Wednesday 19:00–20:30. interior and the splendid view of the won- museum is housed in a former naval store- Welcome reception at the Sofitel Legend derful rose garden allow for an exceptional house constructed in 1656 and is a reminder The Grand. Drinks and light hors d‘oeuvres dining experience. of how significantly Dutch culture has been will be served in the Admiralty Room and Dress code: Business casual attire, jacket not shaped by the sea. Today, the architecture the courtyard. required blends historic architecture with contem- Dress code: Smart casual Meeting point for bus transport in hotel lob- porary features such as the magnificent in- by at 18:15 ner courtyard with its spectacular glass roof Thursday at 19:00 while retaining all the maritime allure of days Cocktails and dinner will be held at Rosarium, Friday at 19:30 gone by. which is located in the middle of the green The IS3R Gold Medal Dinner will be held at Dress code: Dinner attire, jacket required environment of the beautiful Amstelpark in the National Maritime Museum. The recep- Boat will depart from Sofitel Legend The the south of Amsterdam. The restaurant is tion at the museum will be preceded by a Grand at 18:30 known for its innovative cuisine and superb boat ride along the 17th-century canals of atmosphere. The comfortable and modern Amsterdam. Located at the waterfront, the Please note that pre-registration to the Thursday and Friday social events was required. If your plans have changed, kindly notify the registration desk at 16 your earliest convenience. CORPORATE MEMBERS

Platinum General Electric Healthcare Technologies Philips Healthcare Siemens Healthcare Toshiba America Medical Systems

Gold Affidea Alliance Medical Group Bayer Healthcare LL C Bracco Diagnostics Inc. Hitachi, Ltd. Hologic, Inc. Laboratoire Guerbet, SA Time Medical Systems

Silver Agfa-Gevaert, N.V. Carestream Health Elekta Instrument AB Sirtex Medical Europe GmbH

17 © Dietmar Rabich, rabich.de Rabich, Dietmar ©

18 List of Participants

Bibb Allen Eudes Bouvet-Welby Byung Ihn Choi Chairman, Board of Chancellors Marketing Product Manager EMEA Professor, Department of Radiology American College of Radiology Sirtex Medical Europe GmbH Seoul National University Hospital Reston, VA/US Bonn/DE Seoul/KR

Ronald Arenson William G. Bradley Claus D. Claussen Alexander R. Margulis Distinguished Professor and Chairman Emeritus Professor of Radiology Professor and Chairman, Department of University of California, San Diego Eberhard-Karls-Universität Tübingen Radiology and Biomedical Imaging San Diego, CA/US Tübingen/DE University of California, San Francisco San Francisco, CA/US James A. Brink Olivier Clément Radiologist-in-Chief, Juan M. Taveras Professor and Chairman of the Imaging Peter Aspelin Professor of Radiology Department Professor, Department of Radiology Massachusetts General Hospital, Harvard Hôpital Européen Georges Pompidou, Karolinska Institute Medical School Université René Descartes Paris Stockholm/SE Boston, MA/US Paris/FR

Peter Baierl Boris Brkljacic Jian-Ping Dai Executive Director Professor and Chairman, Department of Professor and Chairman of Radiology European Society of Radiology (ESR) Radiology Beijing Tian Tan Hospital Vienna/AT Vice-dean, University of Zagreb School of Beijing/CN Medicine Sébastien Ballet University Hospital “Dubrava” Jörg F. Debatin Head of Drug Discovery Zagreb/HR Vice President Guerbet Chief Technology and Medical Officer Aulnay-sous-Bois/FR Ger Brophy GE Healthcare Chief Technology Officer, Life Sciences Waukesha, WI/US Thomas Balzer GE Healthcare VP, Head Medical and Clinical Affairs Amersham/UK Marc Dewey Radiology Heisenberg Professor of Radiology Bayer HealthCare Medical Care R. Nick Bryan Charité – Universitätsmedizin Berlin Whippany, NJ/US Emeritus Professor of Radiology Berlin/DE University of Pennsylvania Stanley Baum Philadelphia, PA/US Jan De Witte Professor of Radiology, Emeritus Chairman President and CEO, Healthcare IT of Radiology Rob Cascella GE Healthcare University of Pennsylvania Executive Vice President, CEO Diagnostic Buc/FR Philadelphia, PA/US Imaging Royal Philips Adrian K. Dixon Guy Blomfield Andover, MA/US and Amsterdam/NL Emeritus Professor of Radiology, Master of Chief Executive Officer Peterhouse, Alliance Medical Group Carlo Catalano University of Cambridge London/UK Department of Radiology Cambridge/UK Sapienza University of Rome Lorenzo Bonomo Rome/IT Luis Donoso Professor of Radiology Director, Diagnostic Imaging Department Università Cattolica Sacro Cuore Giovanni Cerri Hospital Clinic, University of Barcelona Rome/IT Professor and Chairman, Department of Barcelona/ES Radiology University of São Paulo São Paulo/BR

19 List of Participants

N. Reed Dunnick Ricardo D. Garcia-Monaco Bernd K. Hamm Fred Jenner Hodges Professor and Chair, Professor and Chairman, Department of Professor and Chair, Department of Department of Radiology Radiology Radiology University of Michigan Hospital Italiano de Buenos Aires Charité; Humboldt - Universität zu Berlin Ann Arbor, MI/US Buenos Aires/AR and Freie Universität Berlin Berlin/DE Dieter R. Enzmann Jonas Gårding Leo G. Rigler Chair and Distinguished Director Research & Physics, Neuroscience Kevin Harris Professor Elekta Instrument AB Chief Executive officer University of California, Los Angeles Stockholm/SE CureMetrix Los Angeles, CA/US San Diego, CA/US Hassen A. Gharbi Xiaoyuan Feng Professor of Biophysics and Radiology Christian J. Herold Chairman, Department of Radiology, Immediate Past President of the World Professor of Radiology and Chairman, Huashan Hospital, Immediate Past President Federation for Ultrasound in Medicine and Department of Biomedical Imaging and of Chinese Society of Radiology Biology (WFUMB) Image-Guided Therapy Fudan University Tunis/TN Medical University of Vienna Shanghai/CN Vienna/AT Stephen Golding Jürgen Feuerstein Previously Chairman of Radiology, Oxford Bruce J. Hillman Managing Director University Hospitals Professor of Radiology and Medical Imaging b.e.imaging GmbH University College, Oxford and Public Health Sciences Baden-Baden/DE Oxford/UK Editor-in-Chief, Journal of the American College of Radiology Lori Fontaine Moshe Graif University of Virginia Vice President, Clinical Affairs Chair, Department of Medical Imaging Charlottesville, VA/US Hologic, Inc. The Tel Aviv Sourasky Medical Centre Marlborough, MA/US Tel Aviv/IL Mark Holmshaw Director, Vice President Sales, Marketing Micol Fornaroli Philippe A. Grenier and Service Europe Chief Strategy Officer Professor and Chairman of Radiology Toshiba Medical Systems Europe Bracco Imaging SpA Pitié-Salpêtière Hospital and University Zoetermeer/NL Milan/IT Pierre & Marie Curie Paris/FR Hiroshi Honda Guy Frija Professor and Chairman, Department of Professor and Consultant, Imaging Thomas M. Grist Radiology, Graduate School of Medical Department Professor and Chair, Department of Sciences Hôpital Européen Georges Pompidou, Radiology Kyushu University Université René Descartes Paris University of Wisconsin Fukuoka/JP Paris/FR Madison, WI/US Frans van Houten Michael Fuchsjäger Rolf W. Günther Chief Executive Officer Professor of Radiology, Head of Division of Distinguished Professor Royal Philips General Radiology Charité, University Hospital, Institute of Amsterdam/NL Medical University Graz Radiology Graz/AT Berlin/DE Hedvig Hricak Chairman, Department of Radiology Sanjiv Sam Gambhir Micheal Haimour Carroll and Milton Petrie Chair Professor and Chair, Department of General Manager Global Partnership Memorial Sloan Kettering Cancer Center Radiology Programs New York, NY/US Stanford University School of Medicine GE Healthcare Stanford, CA/US Waukesha, WI/US

20 List of Participants

Rowland Illing Herbert Y. Kressel Barbara J. McNeil Chief Medical Officer Miriam H. Stoneman Professor of Radiology, Professor of Radiology Affidea Editor of RADIOLOGY Professor and Chair, Department of Health London/UK Harvard Medical School, Radiological Care Policy Society of North America Harvard Medical School Valerie P. Jackson Boston, MA/US Boston, MA/US Executive Director The American Board of Radiology Gabriel P. Krestin Carolyn C. Meltzer Tucson, AZ/US Professor and Chair, Department of William P. Timmie Professor and Chair of Radiology Radiology and Imaging Sciences, Associate James Jay Erasmus University Medical Center Dean for Research Global Vice President, Imaging IT Solutions Rotterdam/NL Emory University, School of Medicine Agfa HealthCare Atlanta, GA/US Elmwood Park, NJ/US Eric Lancelot Medical and Regulatory Affairs – Europe Mark A. Mintun Zhengyu Jin Manager President & Chief Medical Officer Chair, Department of Radiology Guerbet Avid Radiopharmaceuticals, Inc. Peking Union Medical College Hospital Roissy CDG Cedex/FR Philadelphia, PA/US Beijing/CN Denis Le Bihan Bernd Montag Arthur Kaindl Director CEO Healthcare HC IM SY CEO, Imaging and Therapy NeuroSpin Siemens Healthcare GmbH Systems, Syngo Gif/Yvette/FR Erlangen/DE Siemens Healthcare GmbH Erlangen/DE Jonathan S. Lewin Dimitris Moulavasilis Senior Vice President, Integrated Healthcare Chief Executive Officer Willi A. Kalender Delivery Affidea Professor and Chairman, Institute of Professor and Chairman, Russell H. Morgan Budapest/HU Medical Physics Department of Radiology and Radiological University of Erlangen Science Charles Niehaus Erlangen/DE Johns Hopkins Medical School Chief Medical Officer Baltimore, MD/US Alliance Medical Group Karim Karti London/UK VP & Chief Marketing Officer Q. Y. Ma GE Healthcare Chairman and Chief Executive Officer Loren T. Niklason UK Time Medical Systems Vice President, Imaging Clinical Research Hologic, Inc. Pek-Lan Khong Rich Mather Bedford, MA/US Professor and Head, Department of Senior Director Global Clinical Research Radiology Toshiba Medical Research Institute USA Bernd Ohnesorge The University of Hong Kong, Queen Mary Newport Beach, CA/US CEO Business Unit Magnetic Resonance Hospital Siemens Healthcare GmbH Hong Kong/CN Walter Märzendorfer Erlangen/DE CEO, Computed Tomography & Radiation Keiji Kobashi Oncology Diego Olego Chief Researcher, Research & Development Siemens Healthcare Head of Technology and R&D Group Erlangen/DE Management, Innovation Hitachi, Ltd. Senior Vice President Tokyo/JP Maryanne McHugh Philips Healthcare Global Strategic Advisor Andover, MA/US Toshiba Corporation Healthcare Company Tokyo/JP

21 List of Participants

Noboyuki Osakabe Osman Ratib Steven E. Seltzer Chief Technology Officer, Healthcare Professor and Head of Nuclear Medicine Professor, Department of Radiology Company and Molecular Imaging, Dept. of Medical Harvard Medical School Hitachi, Ltd. Imaging and Information Sciences Boston, MA/US Tokyo/JP University Hospital of Geneva Geneva/CH Valentin Sinitsyn András Palkó Chief, Department of Radiology Chairman and Head of Department of Maximilian F. Reiser Federal Center of Medicine and Radiology Dean of the Medical Faculty, Director of the Rehabilitation University of Szeged Institute of Clinical Radiology Moscow/RU Szeged/HU Ludwig-Maximilians University Hospital, Campus Grosshadern Kofoworola O. Soyebi Norbert J. Pelc Munich/DE Senior Lecturer & Consultant Radiologist Professor of Bioengineering and Radiology, College of Medicine, University of Lagos & Chair of Bioengineering Hans G. Ringertz Lagos University Teaching Hospital Stanford University Medical Center Consulting Professor of Radiology Lagos/NGA Stanford, CA/US Stanford University Medical Center Stanford, CA/US Gregory Sorensen Josef Penninger President and CEO Scientific Director Geoffrey D. Rubin Siemens Healthcare, North America IMBA – Institute of Molecular George Geller Professor of Radiology and Malvern, PA/US Biotechnology of the Austrian Academy of Biomedical Engineering Sciences Duke University School of Medicine Alberto Spinazzi Vienna/AT Chapel Hill, NC/US Senior Vice President, Global Medical and Regulatory Affairs Roderic I. Pettigrew Amit M. Saindane Bracco Diagnostics, Inc. Director Associate Professor, Department of Monroe Township, NJ/US National Institute of Biomedical Imaging Radiology and Imaging Sciences and Bioengineering Emory University School of Medicine Jacob (Bram) Stolk Bethesda, MD/US Atlanta, GA/US VP and General Manager, Global Research GE Healthcare Homer H. Pien Mitchell D. Schnall Waukesha, WI/US Senior Vice President for Lead Innovations Eugene P. Pendergrass Professor of and Chief Technology Officer Imaging Radiology, Chairman Department of Kazuro Sugimura Systems Radiology Professor, Department of Radiology Royal Philips University of Pennsylvania Kobe University Graduate School of Andover, MA/US Philadelphia, PA/US Medicine Kobe/JP Mathias Prokop Stefan O. Schönberg Professor and Chairman, Department of Director, Department of Clinical Radiology Hisashi Tachizaki Radiology and Nuclear Medicine General Manager, Center for Medical Radboud University Medical Centre University Medical Centre Mannheim Research & Development Nijmegen/NL Mannheim/DE Toshiba Medical Systems Corporation Tochigi /JP Eckhard Puchert Markus Schwaiger Head of SBU Radiology Professor and Director, Department of Sergey Ternovoy Bayer HealthCare Medical Care Nuclear Medicine Academician RAS Berlin/DE Technische Universität München Professor and Chairman, Department of Munich/DE Radiology I.M. Sechenov First Moscow State Medical University Moscow/RU

22 List of Participants

William T. Thorwarth Chief Executive Officer American College of Radiology Reston, VA/US

James H. Thrall Chairman Emeritus, Department of Radiology Massachusetts General Hospital Boston, MA/US

Gustav K. von Schulthess Professor, Chairman and Director emeritus Dept. Med. Radiology and Nuclear Medicine Delegate for Special Tasks University Hospital Zurich Zurich/CH

Yuri Wedmid Senior Vice President Business Development Time Medical Systems US

Ralph Weissleder Thrall Family Professor of Radiology and Professor of Systems Biology Director, Center for Systems Biology Massachusetts General Hospital Boston and Harvard Medical School Boston, MA/US

Huadan Xue Associate Professor and Assistant Director, Department of Radiology Peking Union Medical College Hospital Beijing/CN

23 11th Biennial International Symposium of the International Society for Strategic Studies in Radiology IS3R 2015 Amsterdam/The Netherlands August 27–29, 2015 Scientific Program 24