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Curriculum Vitae Kenji Mizuseki, M.D., Ph.D Curriculum Vitae Kenji Mizuseki, M.D., Ph.D. Personal Information Office address Allen Institute for Brain Science 551 N 34th Street, Seattle, WA 98103, U.S.A. Office phone 1-206-548-8417 Cell phone 1-973-202-4325 E-mail [email protected] [email protected] Web http://www.alleninstitute.org/our-institute/our-team/profiles/kenji-mizuseki Research Experience Senior Scientist, September 2012 – present Allen Institute for Brain Science, WA, U.S.A Research Assistant Professor, March 2012 – August 2012 Neuroscience Institute, New York University, NY, U.S.A. Advisor: Prof. György Buzsáki Research Assistant Professor, March 2009 – March 2012 Center for Molecular and Behavioral Neuroscience, Rutgers University, NJ, U.S.A. Advisor: Prof. György Buzsáki Post-doctoral Fellow, April 2004 – March 2009 Center for Molecular and Behavioral Neuroscience, Rutgers University, NJ, U.S.A. Advisor: Prof. György Buzsáki Staff Research Scientist, March 2002 – March 2004 Center for Developmental Biology, RIKEN, Kobe, Japan Advisor: late Dr. Yoshiki Sasai, Group Leader Research Fellow, Japan Society for the Promotion of Science, April 2000 – February 2002 Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan Advisor: late Prof. Yoshiki Sasai Page 1 of 8 Kenji Mizuseki Education Ph.D. in Medicine, March 2000 Graduate School of Medicine, Kyoto University, Kyoto, Japan Advisors: Prof. Shigetada Nakanishi and late Associate Prof. Yoshiki Sasai M.D., March 1996 Faculty of Medicine, Kyoto University, Kyoto, Japan Publications Diba,K., Amarasingham. A., Mizuseki,K., and Buzsáki, G. (2014). Millisecond timescale synchrony among hippocampal neurons. J. Neurosci. 34, 14984-14994. Schomburg, E.W., Fernández-Ruiz, A., Mizuseki, K., Berényi, A., Anastassiou, C.A., Koch, C., and Buzsáki, G. (2014). Theta phase segregation of input-specific gamma patterns in entorhinal-hippocampal networks. Neuron 84, 470-485. Mizuseki,K.*, Diba,K., Pastalkova,E., Teeters,J., Sirota,A., and Buzsáki,G.* (*corresponding author) (2014). Neurosharing: Large-scale data sets (spike, LFP) recorded from the hippocampal-entorhinal system in behaving rats. F1000 Research. 3:98. Agarwal,G., Stevenson,I.H., Berenyi,A., Mizuseki,K., Buzsaki,G., and Sommer,F.T. (2014). Spatially distributed local fields in the hippocampus encode rat position. Science 344, 626-630. Buzsaki,G., and Mizuseki,K. (2014). The log-dynamic brain: how skewed distributions affect network operations. Nat. Rev. Neurosci. 15, 264-278. Sullivan,D., Mizuseki,K., Sorgi,A., and Buzsaki,G. (2014). Comparison of sleep spindles and theta oscillations in the hippocampus. J. Neurosci. 34, 662-674. Mizuseki,K., and Buzsaki,G. (2014). Theta oscillations decrease spike synchrony in the hippocampus and entorhinal cortex. Philos. Trans. R. Soc. Lond B Biol. Sci. 369, 20120530. Mizuseki,K.* and Buzsaki,G.* (*corresponding author) (2013). Preconfigured, skewed distribution of firing rates in the hippocampus and entorhinal cortex. Cell Rep. 4, 1010-1021. Taxidis,J., Mizuseki,K., Mason,R., and Owen,M.R. (2013). Influence of slow oscillation on hippocampal activity and ripples through cortico-hippocampal synaptic interactions, analyzed by a cortical-CA3-CA1 network model. Front Comput. Neurosci. 7, 3. Stevenson,I.H., London,B.M., Oby,E.R., Sachs,N.A., Reimer,J., Englitz,B., David,S.V., Shamma,S.A., Blanche,T.J., Mizuseki,K., Zandvakili,A., Hatsopoulos,N.G., Miller,L.E., and Kording,K.P. (2012). Page 2 of 8 Kenji Mizuseki Functional connectivity and tuning curves in populations of simultaneously recorded neurons. PLoS. Comput. Biol. 8, e1002775. Grosmark,A.D., Mizuseki,K., Pastalkova,E., Diba,K., and Buzsaki,G. (2012). REM sleep reorganizes hippocampal excitability. Neuron 75, 1001-1007. Vandecasteele,M., M S, Royer,S., Belluscio,M., Berenyi,A., Diba,K., Fujisawa,S., Grosmark,A., Mao,D., Mizuseki,K., Patel,J., Stark,E., Sullivan,D., Watson,B., and Buzsaki,G. (2012). Large-scale recording of neurons by movable silicon probes in behaving rodents. J. Vis. Exp. e3568. Mizuseki,K., Royer,S., Diba,K., and Buzsaki,G. (2012). Activity dynamics and behavioral correlates of CA3 and CA1 hippocampal pyramidal neurons. Hippocampus 22, 1659-1680. Belluscio,M., Mizuseki,K., Schmidt,R., Kempter,R., and Buzsaki,G. (2012). Cross-frequency phase-phase coupling between theta and gamma oscillations in the hippocampus. J. Neurosci. 32, 423-435. Mizuseki,K., Diba,K., Pastalkova,E., and Buzsaki,G. (2011). Hippocampal CA1 pyramidal cells form functionally distinct sublayers. Nat. Neurosci. 14, 1174-1181. Sullivan,D., Csicsvari,J., Mizuseki,K., Montgomery,S., Diba,K., and Buzsaki,G. (2011). Relationships between hippocampal sharp waves, ripples, and fast gamma oscillation: influence of dentate and entorhinal cortical activity. J. Neurosci. 31, 8605-8616. Geisler,C., Diba,K., Pastalkova,E., Mizuseki,K., Royer,S., and Buzsaki,G. (2010). Temporal delays among place cells determine the frequency of population theta oscillations in the hippocampus. Proc. Natl. Acad. Sci. U. S. A. 107, 7957-7962. Mizuseki,K., Sirota,A., Pastalkova,E., and Buzsaki,G. (2009). Theta oscillations provide temporal windows for local circuit computation in the entorhinal-hippocampal loop. Neuron 64, 267-280. Itskov,V., Pastalkova,E., Mizuseki,K., Buzsaki,G., and Harris,K.D. (2008). Theta-mediated dynamics of spatial information in hippocampus. J. Neurosci. 28, 5959-5964. Isomura,Y., Sirota,A., Ozen,S., Montgomery,S., Mizuseki,K., Henze,D.A., and Buzsaki,G. (2006). Integration and segregation of activity in entorhinal-hippocampal subregions by neocortical slow oscillations. Neuron 52, 871-882. Yamazoe,H., Kobori,M., Murakami,Y., Yano,K., Satoh,M., Mizuseki,K., Sasai,Y., and Iwata,H. (2006). One-step induction of neurons from mouse embryonic stem cells in serum-free media containing vitamin B12 and heparin. Cell Transplant. 15, 135-145. Ikeda,H., Osakada,F., Watanabe,K., Mizuseki,K., Haraguchi,T., Miyoshi,H., Kamiya,D., Honda,Y., Sasai,N., Yoshimura,N., Takahashi,M., and Sasai,Y. (2005). Generation of Rx+/Pax6+ neural retinal precursors Page 3 of 8 Kenji Mizuseki from embryonic stem cells. Proc. Natl. Acad. Sci. U. S. A 102, 11331-11336. Yamazoe,H., Murakami,Y., Mizuseki,K., Sasai,Y., and Iwata,H. (2005). Collection of neural inducing factors from PA6 cells using heparin solution and their immobilization on plastic culture dishes for the induction of neurons from embryonic stem cells. Biomaterials 26, 5746-5754. Watanabe,K., Kamiya,D., Nishiyama,A., Katayama,T., Nozaki,S., Kawasaki,H., Watanabe,Y., Mizuseki,K., and Sasai,Y. (2005). Directed differentiation of telencephalic precursors from embryonic stem cells. Nat. Neurosci. 8, 288-296. Irioka,T., Watanabe,K., Mizusawa,H., Mizuseki,K., and Sasai,Y. (2005). Distinct effects of caudalizing factors on regional specification of embryonic stem cell-derived neural precursors. Brain Res. Dev. Brain Res. 154, 63-70. Mizuseki,K., Sakamoto,T., Watanabe,K., Muguruma,K., Ikeya,M., Nishiyama,A., Arakawa,A., Suemori,H., Nakatsuji,N., Kawasaki,H., Murakami,F., and Sasai,Y. (2003). Generation of neural crest-derived peripheral neurons and floor plate cells from mouse and primate embryonic stem cells. Proc. Natl. Acad. Sci. U. S. A 100, 5828-5833. Kawasaki,H., Suemori,H., Mizuseki,K., Watanabe,K., Urano,F., Ichinose,H., Haruta,M., Takahashi,M., Yoshikawa,K., Nishikawa,S., Nakatsuji,N., and Sasai,Y. (2002). Generation of dopaminergic neurons and pigmented epithelia from primate ES cells by stromal cell-derived inducing activity. Proc. Natl. Acad. Sci. U. S. A 99, 1580-1585. Kawasaki,H., Mizuseki,K., and Sasai,Y. (2002). Selective neural induction from ES cells by stromal cell-derived inducing activity and its potential therapeutic application in Parkinson's disease. Methods Mol. Biol. 185, 217-227. Sasai,N., Mizuseki,K., and Sasai,Y. (2001). Requirement of FoxD3-class signaling for neural crest determination in Xenopus. Development 128, 2525-2536. Kawasaki,H., Mizuseki,K., Nishikawa,S., Kaneko,S., Kuwana,Y., Nakanishi,S., Nishikawa,S.I., and Sasai,Y. (2000). Induction of midbrain dopaminergic neurons from ES cells by stromal cell-derived inducing activity. Neuron 28, 31-40. Matsui,M.*, Mizuseki,K.* (* equal contribution), Nakatani,J., Nakanishi,S., and Sasai,Y. (2000). Xenopus kielin: A dorsalizing factor containing multiple chordin-type repeats secreted from the embryonic midline. Proc. Natl. Acad. Sci. U. S. A 97, 5291-5296. Nakatani,J., Mizuseki,K., Tsuda,H., Nakanishi,S., and Sasai,Y. (2000). Xenopus Xenf: an early endodermal nuclear factor that is regulated in a pathway distinct from Sox17 and Mix-related gene pathways. Mech. Dev. 91, 81-89. Page 4 of 8 Kenji Mizuseki Kishi,M., Mizuseki,K., Sasai,N., Yamazaki,H., Shiota,K., Nakanishi,S., and Sasai,Y. (2000). Requirement of Sox2-mediated signaling for differentiation of early Xenopus neuroectoderm. Development 127, 791-800. Mizuseki,K., Kishi,M., Shiota,K., Nakanishi,S., and Sasai,Y. (1998). SoxD: an essential mediator of induction of anterior neural tissues in Xenopus embryos. Neuron 21, 77-85. Mizuseki,K., Kishi,M., Matsui,M., Nakanishi,S., and Sasai,Y. (1998). Xenopus Zic-related-1 and Sox-2, two factors induced by chordin, have distinct activities in the initiation of neural induction. Development 125, 579-587. Data sharing Mizuseki,K., Sirota,A., Pastalkova,E., Diba,K., and Buzsáki,G. (2013). Multiple single unit recordings from different rat hippocampal and entorhinal regions while the animals were performing multiple behavioral
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