Authors: Pallavi Subhraveti Ron Caspi Peter Midford Peter D Karp An online version of this diagram is available at BioCyc.org. Biosynthetic pathways are positioned in the left of the cytoplasm, degradative pathways on the right, and reactions not assigned to any pathway are in the far right of the cytoplasm. Transporters and membrane are shown on the membrane. Ingrid Keseler Periplasmic (where appropriate) and extracellular reactions and proteins may also be shown. Pathways are colored according to their cellular function. Gcf_000317615Cyc: Dactylococcopsis salina PCC 8305 Cellular Overview Connections between pathways are omitted for legibility. Anamika Kothari

a sulfonate glycine betaine glycine betaine glycine betaine pro pro ammonium ammonium hydrogencarbonate nitrate hydrogencarbonate phosphate phosphate phosphate phosphate pro pro pro nitrate

RS15670 RS08720 RS10615 RS07690 RS05530 RS17475 RS03390 RS06795 RS08115 RS14450 RS15135 RS11065 RS15325 RS07155 RS12795

glycine betaine glycine betaine glycine betaine a sulfonate ammonium ammonium nitrate hydrogencarbonate pro pro pro pro pro hydrogencarbonate phosphate phosphate phosphate phosphate phosphate nitrate

5-amino-5-(4- a reduced an sn-glycero-3- UDP-N-acetyl- an N-terminal- Inorganic Nutrient an oxidized a lipid II H + RS00790 H + Amine and Polyamine Fermentation mixed acid fermentation hydroxybenzyl)- SAM + ferredoxin [iron- phospho-N-(acyl) α-D-muramoyl- L-methionyl-L- 3-sulfino-L-alanine thioredoxin H ADP ATP Biosynthesis 6-(D-ribitylimino) sulfur] cluster ethanolamine L-alanyl-γ-D- alanyl-[] gln Aminoacyl-tRNA Charging glutaminyl-tRNA biosynthesis via transamidation assimilatory selenate reduction -5,6-dihydrouracil glutamyl-meso-2,6- spermidine biosynthesis III phosphoenolpyruvate D-alanyl-D-alanine sulfate reduction IV diaminopimeloyl- type I methionyl SufS family F0F1 ATP ferredoxin glycerophosphoryl carboxypeptidase/ H + H + 7,8-didemethyl- thioredoxin diester D-alanyl-D-alanine D-alanyl-D-alanine- aminopeptidase: ATP synthase glu phosphoenolpyruvate sulfate selenate arg pyruvate kinase: 8-hydroxy-5- reductase phosphodiesterase: endopeptidase: dacB map adenylyltransferase desulfurase: carboxylase: DACSA_RS11410 sulfate sulfate (5',5'''-P-1,P-4- deazariboflavin subunit alpha: DACSA_RS02715 D-alanyl-D-alanine penicillin- type I methionyl sufS SAM putrescine DACSA_RS08730 [+ 2 isozymes] adenylyltransferase: sat adenylyltransferase: sat tetraphosphate F0F1 ATP biosynthetic adenosine 5'- synthase subunit DACSA_RS06960 glycerophosphoryl carboxypeptidase/ binding aminopeptidase: + + biosynthesis I II): H H APS phosphoselenate CofG: cofG ferredoxin:thioredoxin diester D-alanyl-D-alanine- protein map synthase spermidine biosynthesis I DACSA_RS10155 sulfite an L-glutamyl- adenosylmethionine decarboxylase: oxaloacetate pyruvate reductase: phosphodiesterase: endopeptidase: dacB 2: mrdA ala arg adenylyl-sulfate 7,8-didemethyl- gln [tRNA Gln ] decarboxylase: speD speA 8-hydroxy-5- DACSA_RS08985 DACSA_RS05430 biosynthetic kinase: cysC penicillin- an N-terminal L- sulfate RS06830 sulfate SAM deazariboflavin binding a N- met alanyl-[protein] Asp-tRNA(Asn) Asp-tRNA(Asn) dAdoMet agmatine arginine formate C- Ap4A PAPS selenite synthase subunit an oxidized protein D-ala acetylglucosamine- /Glu-tRNA(Gln) /Glu-tRNA(Gln) decarboxylase: acetyltransferase: pflB a reduced sn-glycerol an N- CofH: cofH ferredoxin [iron- 2: mrdA -N-acetylmuramyl- amidotransferase amidotransferase adenosylmethionine speA thioredoxin 3-phosphate acylethanolamine nitrite nitrite subunit GatC: gatC polyamine decarboxylase: speD agmatine (S)-malate (R)-lactate phosphoadenosine sulfur] cluster (tetrapeptide) RS15985 subunit GatC: gatC aminopropyltransferase: phosphosulfate formate formate [+ 2 isozymes] acetyl-CoA formate 7,8-didemethyl- UDP-N- pyrophosphoryl- [+ 9 isozymes] a 5-phosphooxy- DACSA_RS15270 putrescine dAdoMet agmatinase: C: reductase: cysH 5'-deoxyadenosine 8-hydroxy-5- met D-ala acetylmuramoyl- undecaprenol DACSA_RS09075 selenodiglutathione ammonium L-glutamyl- speB citrate synthase: phosphoadenosine deazariboflavin L-alanyl-γ-D- [tRNA Gln ] N 1 -(3-aminopropyl) bifunctional phosphosulfate sulfite RS00840 sulfite polyamine fumarate DACSA_RS12505 glutamyl-meso-2,6- agmatine putrescine acetaldehyde- reductase: cysH diaminopimeloyl- Asp-tRNA(Asn) aminopropyltransferase: CoA/alcohol DACSA_RS15270 fumarate reductase/ citrate acetyl phosphate CO H D-alanine /Glu-tRNA(Gln) dehydrogenase: adhE 2 2 sulfite succinate glutathioselenol Fe 2+ RS03480 Fe 2+ bifunctional amidotransferase dehydrogenase sulfite reductase, aconitate hydratase acetate kinase: N-acetyl-muramoyl-(L- sn-glycero-3- (4R)-4-hydroxy- magnesium- an N-terminal- subunit GatC: gatC spermidine spermidine flavoprotein subunit: acetaldehyde ferredoxin adenosylcobinamide a purine H O alanyl-γ-D-glutamyl-L- diphosphate 2 phospho-N- protoporphyrin IX L-methionyl-L- L-selenocysteine [+ 2 isozymes] 2/2-methylisocitrate DACSA_RS11230 2-oxoglutarate DACSA_RS06815 dependent: sir ribonucleoside lysyl-D-alanyl-D-alanine) (arachidonoyl) 13-monomethyl ester seryl-[protein] a reduced : acnB bifunctional magnesium- acetate 5'-triphosphate ethanolamine H O c-type an L-glutaminyl- succinate acetaldehyde- hydrogen sulfide hydrogen selenide bifunctional protoporphyrin 2 cytochrome tRNA charging cis-aconitate CoA/alcohol D-alanyl-D-alanine RdgB/HAM1 family type I methionyl SufS family ancytochrome oxidized [tRNA Gln ] bifunctional 4-hydroxy-2- IX monomethyl c oxidase dehydrogenase: adhE carboxypeptidase/ non-canonical glycerophosphoryl aminopeptidase: cysteine O c-type bifunctional adenosylcobinamide oxoglutarate ester (oxidative) 2 D-alanyl-D-alanine- purine NTP map desulfurase: UQ UQ cytochrome phe a tRNA Phe aconitate hydratase kinase/ diester aldolase/2- cyclase: acsF RS13760 ethanol pyrophosphatase: sufS NADH NADH Gly 2/2-methylisocitrate endopeptidase: dacB phosphodiesterase: type I methionyl gly a tRNA pyruvate fermentation polyphosphate nitrate reduction VI (assimilatory) adenosylcobinamide- rdgB dehydro-3-deoxy- magnesium- dehydratase: acnB phosphate penicillin-binding DACSA_RS05430 phosphogluconate protoporphyrin aminopeptidase: to ethanol I metabolism inorganic Cys Met Met glu Tyr His phenylalanine- Thr guanylyltransferase: protein 2: mrdA glycerophosphoryl aldolase: IX monomethyl map cys a tRNA elongator tRNA met initiator tRNA met glu a tRNA tyr a tRNA his a tRNA thr a tRNA selenide 2+ 2+ glycine--tRNA -tRNA D-threo-isocitrate nitrate diphosphatase: ala Zn RS03450 Zn arg a tRNA Arg asn tRNA Asn ile a tRNA Ile val a tRNA Val lys a tRNA Lys ser a tRNA ser pro a tRNA Pro leu a tRNA Leu trp a tRNA Trp tRNA asp asp a tRNA Ala ala pyruvate long chain cobU diester DACSA_RS08575 ester (oxidative) subunit alpha: pheS Gln DACSA_RS16185 ligase subunit beta: gln a tRNA NADP-dependent polyphosphate ferredoxin-- adenosyl- N-acetyl-muramoyl-(L- phosphodiesterase: cyclase: acsF an N-terminal Rubisco shunt γ 3,8-divinyl cysteine-- methionine-- methionine-- glutamate-- tyrosine-- histidine-- DACSA_RS12615 phenylalanine--tRNA threonine-- isocitrate nitrate reductase: cobinamide alanyl- -D-glutamyl- D-ala DACSA_RS02715 met L-seryl-[protein] formate C- a tRNA ligase: arginine--tRNA asparagine-- tRNA ligase: tRNA ligase: isoleucine-- tRNA ligase: valine--tRNA ligase: tRNA ligase: lysine--tRNA tRNA ligase: serine--tRNA proline--tRNA glycine--tRNA ligase leucine--tRNA ligase subunit beta: tRNA ligase: tryptophan-- aspartate--tRNA alanine--tRNA DACSA_RS15970 a purine L-lysyl-D-alanine) glyoxylate pyruvate Zn 2+ RS04085 Zn 2+ dehydrogenase: phosphate H + DACSA_RS00395 ligase: argS tRNA ligase: asnS DACSA_RS07340 DACSA_RS07340 tRNA ligase: ileS DACSA_RS07820 DACSA_RS07950 DACSA_RS08705 ligase: lysS DACSA_RS09585 ligase: serS ligase: proS subunit alpha: glyQ ligase: leuS DACSA_RS16245 DACSA_RS14695 tRNA ligase: trpS ligase: aspS ligase: alaS acetyltransferase: polyphosphate ribonucleoside phosphate DACSA_RS02380 F6P sn-glycerol pflB kinase 1: ppk1 nitrite 5'-diphosphate anandamide 2-oxoglutarate 3-phosphate an L-cysteinyl-[tRNA Cys ] an L-arginyl-[tRNA Arg ] an L-asparaginyl-[tRNA Asn ] an L-methionyl-[elongator tRNA Met ] an L-methionyl-[initiator tRNA Met ] an L-isoleucyl-[tRNA Ile ] an L-glutamyl-[tRNA Glu ] an L-valyl-[tRNA Val ] an L-tyrosyl-[tRNA Tyr ] an L-lysyl-[tRNA Lys ] an L-histidyl-[tRNA His ] an L-seryl-[tRNA ser ] an L-prolyl-[tRNA Pro ] a glycyl-[tRNA Gly ] an L-leucyl-[tRNA Leu ] an L-phenylalanyl-[tRNA Phe ] an L-threonyl-[tRNA Thr ] an L-tryptophanyl-[tRNA Trp ] an L-aspartyl-[tRNA asp ] an L-alanyl-[tRNA Ala ] an L-glutaminyl-[tRNA Gln ] transketolase: tkt ferredoxin-- Zn 2+ RS12540 Zn 2+ acetyl-CoA formate nitrite reductase: D-erythrose long chain 10 γ α ε (1S,2R)-1- an N-terminal- an N-terminal- bifunctional DACSA_RS15980 an L-methionyl- an N - L-alanyl- -D-glutamyl-L- N ,N -diacetyl-lysyl- oleoyl-CoA H O 4-phosphate polyphosphate ser C-(indol-3- L-methionyl-L- 2 L-methionyl-L- ser a tRNA sec [initiator tRNA Met ] formyltetrahydrofolate lysyl-D-alanyl-D-alanine D-alanyl-D-alanine acetaldehyde- ammonium yl)glycerol cysteinyl-[protein] valyl-[protein] Zn 2+ RS13135 Zn 2+ CoA/alcohol transaldolase: tal 3-phosphate dehydrogenase: D-alanyl-D-alanine D-alanyl-D-alanine acyl-CoA , Carrier, and Vitamin Biosynthesis methionyl-tRNA type I methionyl type I methionyl serine- adhE glutamine glutamate carboxypeptidase/ carboxypeptidase/ tryptophan thioesterase: D-glyceraldehyde D-sedoheptulose formyltransferase: aminopeptidase: aminopeptidase: -tRNA synthetase: synthase D-alanyl-D-alanine- D-alanyl-D-alanine- synthase DACSA_RS13820 a sugar RS08590 a sugar 3-phosphate 7-phosphate DACSA_RS10990 map map ligase: cob(II)yrinate a,c- acetaldehyde DACSA_RS17490 large endopeptidase: dacB endopeptidase: dacB subunit acyl-CoA [2Fe-2S] iron-sulfur nickel cofactor cob(II)yrinate a,c-diamide flavin biosynthesis I ( and ) glutathione- superpathway of coenzyme A biosynthesis I (bacteria) biotin biosynthesis from 8- NAD de novo biosynthesis lipoate biosynthesis subunit: gltB methionyl-tRNA type I methionyl type I methionyl serS diamide biosynthesis I [+ 2 isozymes] penicillin-binding penicillin- alpha: trpA thioesterase: cluster biosynthesis biosynthesis biosynthesis II (late glutaredoxin amino-7-oxononanoate III I (from aspartate) salvage from cobalamin and incorporation I bifunctional transketolase: tkt formyltransferase: aminopeptidase: aminopeptidase: (early cobalt insertion) 3-methyl-2- a 5,10- protein 2: mrdA binding DACSA_RS09490 a sugar RS13235 a sugar nicotinate adenine cobalt incorporation) redox reactions acetaldehyde- DACSA_RS04890 tryptophan map map -III oxobutanoate methylenetetrahydrofolate (8S)-8-amino-7- protein L-cysteine desulfurase dinucleotide uroporphyrinogen-III GTP glutathione a [protein]-L-lysine asp cob(I)alamin an octanoyl-[acp] CoA/alcohol D- 5- D-xylulose gln glu synthase an L-seryl- oxononanoate sec uroporphyrinogen-III lipoyl(octanoyl) dehydrogenase: phosphate 5-phosphate L-alanyl-γ-D-glutamyl- 2: mrdA subunit [tRNA ] uroporphyrinogen-III 3-methyl-2-oxobutanoate L-aspartate an N-formyl- oleate C-methyltransferase: cysteine adhE D-ala beta: trpB an N-terminal L- an N-terminal 2+ 2+ pyridin-1-ium- C-methyltransferase: bifunctional hypothetical protein: oxidase: nadB L-methionyl- a tetrahydrofolate L-lysyl-D-alanine Co RS07135 Co cobA desulfurase: hydroxymethyltransferase: met cysteinyl-[protein] met L-valyl-[protein] 3,5-dicarboxylate cobA 3,4-dihydroxy- a reduced DACSA_RS17370 2-iminosuccinate cob(II)alamin a [lipoyl-carrier protein]LipB: lipB ribose-5- ribulose-phosphate [initiator tRNA met ] Nα,Nε-diacetyl- uroporphyrinogen-III DACSA_RS16925 panB ethanol D-ala D-glyceraldehyde mononucleotide uroporphyrinogen-III 2-butanone- glutaredoxin N 6 -octanoyl-L-lysine phosphate 3-epimerase: lysyl-D-alanine asp 6 3-phosphate trp C-methyltransferase: an S-sulfanyl-[L- ATP- 4-phosphate a [protein]-N -[(2S quinolinate cob(I)yrinic acid DACSA_RS12965 thiosulfate oxidation III (multienzyme complex) C-methyltransferase: glutaredoxin lipoyl Co 2+ RS10330 Co 2+ cobA dependent synthase 2-dehydropantoate ,3R)-2-amino-8- synthase a,c-diamide RpiA: rpiA cysteine desulfurase] cobA 3: grxC aspartate 1- synthase: lipA precorrin-1 sacrificial RibB/GTP carboxyoctan-3-yl]-L-lysine NadA: nadA adenosyltransferase: precorrin-1 decarboxylase: TCA cycle a [SoxY protein]-L-cysteine sulfur cyclohydrolase glutaredoxin adenosylcobinamide-GDP hypothetical protein: DACSA_RS04460 lipoyl a mature peptidoglycan a 2,3,4-saturated a peptidoglycan an N-terminal- an N-terminal- uroporphyrinogen-III 34 3: grxC DACSA_RS00845 salvage from cobinamide I quinolinate synthase: lipA glycerophosphoserine MoO - a cytidine 2+ 2+ transferase uroporphyrinogen-III II RibA: ribA DACSA_RS17370 cob(I)yrinic acid (meso-diaminopimelate 1,2-diacyl-sn- dimer (S. aureus) L-methionyl-L- 2 L-methionyl- lys Co RS13440 Co C-methyltransferase: a protein with a [lipoyl-carrier partial TCA cycle (obligate autotrophs) ATP Ile2 an S-sulfanyl-[cysteine C-methyltransferase: 2,5-diamino-6- containing) glycerol 3-phosphate CTP threonyl-[protein] molybdopterin glycyl-[protein] in tRNA LarE: larE β carboxylating a,c-diamide 6 cobA (5-phospho-D- reduced L- -alanine (R)-pantoate cob(II)inamide (7R,8S)-8-amino-7- protein]-N -[(R)- cofactor desulfurase]-[disordered- 5-carboxy-1-(5- cobA nicotinate- adenosyltransferase: D-ribulose uroporphyrinogen-III β cysteine residues cob(I)yrinic acid (carboxyamino)nonanoate dihydrolipoyl]-L-lysine a [SoxY protein]-S- D-alanyl-D-alanine glycerophosphoryl form scaffold O-phospho- - uroporphyrinogen-III ribosylamino) cobO phosphoenolpyruvate 5-phosphate membrane-bound phosphatidate tRNA C-methyltransferase: a,c-diamide ATP-dependent sulfosulfanyl-L-cysteine carboxypeptidase/ diester type I methionyl type I methionyl a metal a metal protein] complex D-ribofuranosyl) C-methyltransferase: pyrimidin- cob(II)alamin- phosphoribulokinase: lytic murein cytidylyltransferase: molybdenum cofactor lysidine(34) RS03720 cobA [cysteine desulfurase]-S- bifunctional adenosyltransferase: dethiobiotin diphosphorylase: D-alanyl-D-alanine- phosphodiesterase: aminopeptidase: aminopeptidase: cation cation pyridin-1-ium-3- cobA 4(3H)-one [corrinoid DACSA_RS00600 transglycosylase: DACSA_RS12500 guanylyltransferase: synthetase sulfanylcysteine:[acceptor pantoate--beta- DACSA_RS04460 synthetase DACSA_RS04545 phosphoenolpyruvate cytochrome c: endopeptidase: dacB DACSA_RS02715 map map carbonyl adenylate bifunctional adenosyltranferase] phosphoribulokinase: DACSA_RS14850 DACSA_RS17265 TilS: tilS precorrin-2 protein]-cysteine ATP- alanine ligase/ BioD: bioD thioredoxin carboxylase: acetyl-CoA DACSA_RS11580 phosphatidate penicillin- type I methionyl type I methionyl precorrin-2 diaminohydroxyphosphoribosylaminopyrimidine cob(I)yrinic acid NaMN DACSA_RS08800 glycerophosphoryl sulfurtransferase: dependent (d)CMP kinase: pathway DACSA_RS08730 cytidylyltransferase: binding aminopeptidase: aminopeptidase: a metal RS01165 a metal deaminase/5-amino-6-(5-phosphoribosylamino) DACSA_RS11835 a,c-diamide dethiobiotin D-ribulose-1,5- DACSA_RS06070 diester adenylyl cation cation DACSA_RS16925 sacrificial precorrin-2 C(20)- nicotinate-nucleotide a [SoxY protein]-S- a [SoxY protein]-S a mature peptidoglycan a mature peptidoglycan protein map map a lysidine 34 a [cysteine desulfurase]- uracil reductase RibD: ribD adenosyltransferase: an oxidized bisphosphate phosphodiesterase: molybdenum sulfur methyltransferase: 5-amino-6-(5- adenylyltransferase: cob(I)alamin- disulfanyl-L-cysteine -sulfanyl-L-cysteine with (L-alanyl-γ-D- strand (non- 2: mrdA in tRNA Ile2 S-sulfanyl-[disordered- [corrinoid cobO biotin synthase thioredoxin oxaloacetate DACSA_RS05430 cofactor transferase DACSA_RS04615 D-ribulose phospho-D- DACSA_RS13215 [corrinoid ribulose glutamyl-meso-2,6- reducing terminus) a CDP-2,3,4-saturated- form scaffold (R)-pantothenate adenosyltranferase]- BioB: bioB an N-terminal L- an N-terminal a metal a metal a [LarE]-S-[5-carboxy-LarE: larE 5-phosphate ribosylamino)uracil adenosyltranferase] bisphosphate diaminopimeloyl-D- diacylglycerol met met RS03940 protein] complex precorrin-3A cob(II)inamide nicotinate adenine cob(I)yrinic acid a peptidoglycan threonyl-[protein] glycyl-[protein] cation cation sirohydrochlorin 1-(5-O-phosphono- bifunctional pantothenate citrate synthase: carboxylase alanine) tetrapeptide sn-glycerol cysteine bifunctional 9-mercaptodethiobiotin dinucleotide a,c-diamide thioredoxin- with D,D cross- D-ala ser cobaltochelatase: β-D-ribofuranosyl) diaminohydroxyphosphoribosylaminopyrimidine kinase: DACSA_RS12505 small subunit: 3-phosphate desulfurase: 3,4-dihydroxy- NAD+ synthase: NAD+ synthase: adenosyltransferase: link (S. aureus) DACSA_RS16690 pyridin-1-ium-3- deaminase/5-amino-6-(5-phosphoribosylamino) DACSA_RS03090 DACSA_RS08860 a [SoxY protein]-S-(2- DACSA_RS16925 2-butanone- [corrinoid biotin synthase DACSA_RS13225 DACSA_RS13225 DACSA_RS04460 reductase: (S)-malate a metal a metal an S-sulfanyl-[cysteine carbonyl]-L-cysteine uracil reductase RibD: ribD (R)-4'- citrate sulfodisulfanyl)-L-cysteine RS05665 cobalt- 4-phosphate 5-amino-6-(5- adenosyltranferase]- BioB: bioB trxB 3-phospho- cation cation desulfurase]-S- ATP- cob(I)yrinic acid a peptidoglycan dimer (meso a uridine 38- a peptide with sirohydrochlorin precorrin-3B synthase phosphopantothenate NAD + fumarase C: D-glycerate a nucleoside dependent phospho-D- cob(I)inamide a,c-diamide bifunctional a 5,10-gly a uridine 34 -diaminopimelate containing) KDGP glycerophosphoglycerol an N-terminal cyanate biotin RS04340 biotin sulfanyl-[disordered- RibB/GTP bifunctional biotin DACSA_RS09075 2,3-bisphosphoglycerate- triphosphate RNA 40 in tRNA sacrificial precorrin-3B C(17)- ribitylamino)uracil cob(I)yrinic acid adenosyltransferase: aconitate hydratase methylenetetrahydrofolate in tRNA RluA family L-methionine form scaffold cyclohydrolase phosphopantothenoylcysteine independent a metal a metal protein] complex sulfur methyltransferase: a,c-diamide cobO a reduced 2/2-methylisocitrate urea cycle pseudouridine [cysteine desulfurase]-S- II RibA: ribA decarboxylase/ fumarate phosphoglycerate D-alanyl-D-alanine cyanase: cation cation transferase cobJ adenosyltransferase: adenosylcob(III) thioredoxin dehydratase: acnB bifunctional glycerophosphoryl DNA-directed synthase: RS09140 cobalt-factor III sulfanylcysteine:[acceptor 1-deoxy-L- phosphopantothenate-- mutase: tRNA uridine-5- carboxypeptidase/ type I methionyl cynS LarE: larE DACSA_RS04460 alamin-[corrinoid 4-hydroxy-2- diester RNA polymerase: DACSA_RS09145 protein]-cysteine pyridin-1-ium-3- glycero-tetrulose superpathway of tetrahydrofolate biosynthesis cysteine ligase CoaBC: coaBC cis-aconitate DACSA_RS18090 arg carboxymethylaminomethyl(34) D-alanyl-D-alanine- aminopeptidase: ala ala precorrin-4 ARP cob(I)yrinic acid adenosyltranferase] ammonium oxoglutarate phosphodiesterase: DACSA_RS03235 cyanase: sulfurtransferase: carboxylate-5- 4-phosphate (R)-4'- synthesis MnmG: mnmG endopeptidase: dacB tRNA map a,c-diamide cob(I)yrinic acid 2-phospho- aldolase/2- DACSA_RS05430 DACSA_RS03240 cynS arsenite RS17675 arsenite DACSA_RS16925 thiocarboxylate precorrin-4 C(11)- phosphopantothenoyl- bifunctional carbamoyl- tRNA uridine-5- penicillin-binding pseudouridine(38- type I methionyl a [cysteine adenosyltransferase: a,c-diamide succinate D-glycerate dehydro-3-deoxy- glycerophosphoryl rpoB 40) synthase mononucleotide methyltransferase: GTP L-cysteine cytidylyl molybdenum aconitate hydratase argininosuccinate phosphate synthase carboxymethylaminomethyl(34) protein 2: mrdA aminopeptidase: cobalt-precorrin-3 desulfurase]-(S- ATP- cobM cobO adenosyltransferase: 2/2-methylisocitrate phosphopyruvate phosphogluconate diester [+ 2 isozymes] TruA: truA bifunctional cofactor sulfurylation : argH large subunit: carB synthesis GTPase MnmE: mnmE 38- map ammonium CO sulfanyl) -[disordered- DACSA_RS04460 hydratase: phosphodiesterase: a pseudouridine 2 2 dependent dehydratase: acnB aldolase: 6,7-dimethyl-8-(1- phosphopantothenoylcysteine adenosylcobinamide a peptidoglycan with predicted form scaffold sacrificial precorrin-5 GTP cob(I)yrinic acid cytidylyl molybdenum DACSA_RS09035 glutamine- DACSA_RS08575 DACSA_RS02715 40 in tRNA D-ribityl)lumazine decarboxylase/ 34 ABC protein] complex cyclohydrolase cofactor (trioxo) D-threo-isocitrate phosphoenol hydrolyzing a 5-carboxymethylaminomethyluridine D,D cross-links (meso- D-ala RNA urea urea sulfur phosphopantothenate-- bifunctional a,c-diamide a 7,8-dihydrofolate transporter riboflavin I FolE: folE pyruvate L-arginino-succinate L-ornithine carbamoyl- in tRNA diaminopimelate containing) met a peptide transferase synthase: cysteine ligase CoaBC: coaBC adenosylcobinamide superpathway of thiamine diphosphate biosynthesis II adenosyltransferase: NADP-dependent D-glyceraldehyde glycerol sn-glycerol of urea cobalt-precorrin-4 LarE: larE GTP cobO an [MCD cofactor pyruvate kinase: phosphate synthase pyruvate β ribE kinase/ isocitrate 3-phosphate 3-phosphate 1-(5-O-phospho- - cyclohydrolase 4'-phosphopantetheine chaperone]-MCD DACSA_RS11410 small subunit: carA a [cysteine desulfurase]- D-ribofuranosyl)-5- precorrin-6A adenosylcobinamide- adenosylcobalamin dehydrogenase: riboflavin I FolE: folE cysteine [+ 2 isozymes] [scaffold protein- (sulfanylcarbonyl) 7,8- pantetheine- phosphate cys DACSA_RS02380 ornithine carbamoyl phosphate (2Fe-2S)] complex guanylyltransferase: desulfurase: argininosuccinate a [ribosomal a peptidoglycan a [bis(guanylyl sn-glycero-3- a [histone]-N 6 - D-sedoheptulose pyridin-1-ium-3- bifunctional dihydroneopterin phosphate pyruvate carbamoyltransferase: a sulfurated an L-asparaginyl- cobalt- cysteine DACSA_RS16925 2-oxoglutarate protein S12] dimer (E. faeciums) molybdopterin) cys Asn 1-phosphate carbonyl adenylate 3'-triphosphate adenylyltransferase: cobU synthase: argF [sulfur carrier] phosphoethanolamine acetyl-L-lysine [tRNA ] ATP roseoflavin precorrin-5A ATP- riboflavin kinase/ desulfurase: a [cytidylyl molybdenum DACSA_RS02040 L-aspartate 89 cofactor FAD synthetase: coaD adenosyl-cobinamide 5'-phosphate dependent precorrin-6B DACSA_RS16925 a [ThiS sulfur- cofactor chaperone]- L-citrulline chaperone]- a [co-chaperone]- DACSA_RS12215 3'-dephospho- phosphate 2-carboxy-1,4- NADPH repair () D-alanyl-D-alanine glycerophosphoryl histone - sacrificial SufS family carrier protein] cytidylyl molybdenum 30S ribosomal carboxypeptidase/ L-cysteine aminoacyl-tRNA [scaffold protein- precorrin-6Y C5,15- 7,8- CoA naphthoquinol biosynthesis cofactor (sulfo-dioxo) diester deacetylase: bifunctional bisphosphate sulfur FMN bifunctional cysteine cyanate degradation protein S12 D-alanyl-D-alanine- : cobalt- (2Fe-2S)] complex methyltransferase dihydroneopterin chorismate dephospho- NADPH phosphodiesterase: DACSA_RS15305 riboflavin kinase/ aldolase SSQ1 transferase adenosylcobinamide desulfurase: Respiration methylthiotransferase endopeptidase: dacB cysteine DACSA_RS16870 precorrin-5B subunit CbiT: cbiT 3'-phosphate CoA kinase: chorismate sulfate activation DACSA_RS02715 histone FAD synthetase: class II: fba chaperone: LarE: larE bifunctional aminodeoxychorismate/ kinase/ sufS RimO: rimO desulfurase: cobalt-precorrin- a [LarE]-S-[1-(5-O DACSA_RS15255 isochorismate for sulfonation CO penicillin-binding glycerophosphoryl deacetylase: DACSA_RS12215 dnaK β precorrin-7 riboflavin kinase/ anthranilate synthase adenosylcobinamide- an [L-cysteine a carboxy- 2 DACSA_RS16925 5B (C(1))- -phosphono- -D- synthase: 2-oxoisovalerate decarboxylation to isobutanoyl-CoA carbonic protein 2: mrdA diester DACSA_RS02630 a [chaperone-ATP]- ribofuranosyl)-5- FAD synthetase: component II: coenzyme A phosphate desulfurase]-S- adenylated-[ThiS DACSA_RS00555 glutathione- sulfate anhydrase: a [ribosomal asn tRNA Asn DHAP D-erythrose methyltransferase: [co-chaperone]- precorrin-6Y C5,15- DACSA_RS12215 guanylyltransferase: D-glyceraldehyde sulfanyl-L-cysteine sulfur-carrier protein] 5'-deoxyadenosine an unsulfurated phosphodiesterase: roseoflavin (sulfanylcarbonyl) D-erythro-7,8- DACSA_RS05765 isochorismate peroxide an [apo BCAA sulfate DACSA_RS08840 met protein S12]-3- a peptidoglycan tetramer a [bis(guanylyl DACSA_RS09610 [scaffold protein- methyltransferase cobU 3-phosphate (R)-NADPHX [sulfur carrier] DACSA_RS05430 adenine pyridin-1-ium-3- dihydroneopterin 4-amino-4- gly redox reactions dehydrogenase bifunctional adenylyltransferase: sat methylsulfanyl- with a D,D cross-link D-ala ala molybdopterin) acetate a [histone]-L-lysine cobalt- FAD cysteine 6 (2Fe-2S)] complex subunit CbiT: cbiT 2-succinyl-5- E2 protein] N alpha-ketoacid 89 dinucleotide carbonyl]-L-cysteine dihydroneopterin deoxychorismate adenosylcobinamide- 1-deoxy-D-xylulose- GSSG ADP-dependent APS L-aspartate (Enterococcus faecium) cofactor precorrin-6A desulfurase: enolpyruvyl- -lipoyl-L-lysine dehydrogenase ATP- precorrin-8x aldolase: folB branched-chain GDP glycine 5-phosphate NAD(P)H-hydrate cyanase: chaperone]-S- ethanolamine sn-glycerol cobalt-precorrin- SSQ1 DACSA_RS16925 6-hydroxy-3- subunit beta: dependent oxidase synthase: dihydrolipoyl dehydratase/ adenylyl-sulfate cynS hydrogencarbonate sulfanyl-L-cysteine 3-phosphate 6A reductase: chaperone sacrificial 6-(hydroxymethyl) ThiO: thiO DACSA_RS14860 cyclohexene-1- DACSA_RS06330 NAD(P)H-hydrate DACSA_RS02280 ATPase: dnaK aminotransferase/ a thiocarboxylated- glutathione- dehydrogenase: kinase: cysC cyanase: sulfur -7,8-dihydropterin 1-deoxy-D-xylulose carboxylic-acid epimerase: 4-amino-4- 2-iminoacetate [ThiS sulfur- disulfide lpdA cynS cobalt- transferase 2-amino-4-hydroxy-6- 5-phosphate synthase: menD DACSA_RS09280 PAPS a 5,10- a 2-thiouridine 34 sn-glycerol a CDP- a 1-acyl-2- D-firefly a [chaperone- deoxychorismate carrier protein] 2-succinyl-5-enolpyruvoyl- reductase: an [apo BCAA protoheme H O acetyl-CoA octanoyl-CoA γ-L-glutamyl- precorrin-6B an [2Fe-2S] LarE: larE hydrogenobyrinate hydroxymethyldihydropteridine an [apo BCAA dehydrogenase (S)-NADPHX methylenetetrahydrofolate in tRNA 3-phosphate diacylglycerol arachidonoyl- luciferyl-CoA 2 gly ADP]-[disordered- lyase: AIR 6-hydroxy-3-cyclohexene- gorA dehydrogenase ATP D-alanine cobalt-precorrin- cluster protein pyridin-1-ium-3,5- diphosphokinase: folK E2 protein] N 6 -S-[2- glyphosate sn-glycerol biotin form scaffold DACSA_RS15155 1-deoxy-D-xylulose E2 protein] N 6 15 bisthiocarboxylate (7,8-dihydropterin- 1-carboxylate bifunctional CO 3-phosphate CTP 6B (C )- protein] complex phosphomethylpyrimidine 5-phosphate:thiol methylpropanoyl]dihydrolipoyl- degradation II 2 cyanate tRNA uridine-5- oxygenase acyl-CoA fatty-acid mononucleotide 6-yl)methyl -dihydrolipoyl- ADP-dependent CDP-diacylglycerol-- glutathione methyltransferase non- 4-aminobenzoate pyridoxal 5'-phosphate biosynthesis I synthase: thiC sulfurtransferase: L-lysine carboxymethylaminomethyl(34) (- thioesterase: oxidation protein diphosphate glutathione L-lysine NAD(P)H-hydrate glyphosate glycerol-3-phosphate 3- biotin--[acetyl-CoA- synthase: [decarboxylating]: chaperonin hydrogenobyrinate thiO synthesis enzyme MnmG: mnmG producing): phosphatidate DACSA_RS09490 subunit alpha: (1R,6R)-6-hydroxy-2- dehydratase/ phosphatidyltransferase: carboxylase] ligase: gshB DACSA_RS04375 molecular a,c-diamide D-erythrose HMP-P DACSA_RS12845 cytidylyltransferase: DACSA_RS11870 dihydropteroate 2-[(2R,5Z)-2-carboxy- succinylcyclohexa-2,4- NAD(P)H-hydrate tRNA uridine-5- pgsA acyl-CoA DACSA_RS08945 chaperone pyridin-1-ium- 4-phosphate 2-oxo acid glycine DACSA_RS12500 cobalt-precorrin-7 cobaltochelatase synthase: folP bifunctional 4-methylthiazol-5(2H)- diene-1-carboxylate epimerase: Aromatic Compound Degradation carboxymethylaminomethyl(34) heme oxygenase thioesterase: ATPase: dnaK 3-thioamide-5- dehydrogenase oxidase phosphatidate subunit CobN: cobN vitamin E biosynthesis (tocopherols) hydroxymethylpyrimidine ylidene]ethyl phosphate o-succinylbenzoate DACSA_RS09280 synthesis GTPase MnmE: mnmE 1-(3-sn- (biliverdin- DACSA_RS13820 3-oxodecanoyl- norophthalmate an [Fe-S cluster thiocarboxylate subunit E2: ThiO: thiO CMP cytidylyltransferase: biotinyl-5'- bifunctional cobalt- cob(II)yrinate 7,8- kinase/ synthase: urate conversion to allantoin II phosphatidyl) producing): CoA biosynthesis mononucleotide 3-(4- 4-phospho- DACSA_RS11525 DACSA_RS06070 adenylate precorrin-7 (C(5))- a,c-diamide dihydropteroate phosphomethylpyrimidine DACSA_RS03915 NADPH a 5-aminomethyl-2- -sn-glycerol DACSA_RS09900 methyltransferase/ chaperone]-ATP Ni pincer complex hydroxyphenyl) D-erythronate (aminomethyl) a 7,8-dihydrofolate D-firefly luciferin bifunctional kinase: thiD glyoxylate thiouridine 34 in tRNA 3-phosphate cobalt-precorrin- pyruvate 2-(2-carboxy-4- 2-succinylbenzoate phosphonate urate a CDP-1-acyl- folylpolyglutamate methylthiazol-5- FAD-dependent (Z,Z)- 6B (C(15))- HMP-PP CO Fe 2+ 2-arachidonoyl- synthase/ α methyltransferase: 4-hydroxyphenylpyruvate yl)ethyl phosphate 2-succinylbenzoate- Pentose Phosphate Pathways urate hydroxylase biliverdin-IX glycerol thiamine diphosphate salvage II dihydrofolate (3R)-3-hydroxy-2-oxo- -CoA ligase: HpxO: hpxO DACSA_RS04375 dioxygenase: hppD synthase: molybdopterin biosynthesis 4 phosphooxybutanoate thiamine phosphate DACSA_RS03910 pentose phosphate pathway Secondary Metabolite Degradation (S)-5-hydroxyisourate 4-amino-2-methyl-5- phytyl DACSA_RS00330 synthase: a carboxy- UDP-N-acetylmuramoyl- (+)-7-epi- a very-long-chain an L-cysteinyl- cobalt-precorrin-8 4-(2'-carboxyphenyl) cob(II)inamide γ H O D-glycero-β-D- homogentisate diphosphate hydroxyisourate adenylated- cys L-alanyl- -D- jasmonoyl-CoA 2 fatty aldehyde Cys glu ala pyrimidinemethanol 7,8-dihydrofolate D-glyceraldehyde DACSA_RS06730 cys -4-oxobutyryl-CoA D-glucopyranose ATP ATP manno-heptose [tRNA ] cobalt-precorrin- pyruvate anhydromuropeptides recycling I hydrolase: uraH [ThiS sulfur- glutamyl-meso-2,6- bifunctional monoglutamate 3-phosphate ATP 6-phosphate tRNA-uridine 2-thiolation Macromolecule Modification 1-phosphate 8 methylmutase: 4-phosphooxy- 1,4-dihydroxy-2- carrier protein] diaminopimeloyl- hydroxymethylpyrimidine homogentisate cysteine naphthoyl-CoA glucose-6- and selenation (bacteria) GlcNAc-1,6- (S)-2-oxo-4-hydroxy-4- acyl-CoA aldehyde DACSA_RS04370 L-threonine thiamine phosphate cob(I)yrinic acid a,c-diamide D-alanine aminoacyl-tRNA glutamate- kinase/ phytyltransferase: 1-deoxy-D-xylulose- molybdopterin- desulfurase: synthase: menB phosphate anhMurNAc- carboxy-5-ureidoimidazoline thioesterase: oxygenase 4-hydroxythreonine- γ adenosyltransferase: cobO cysteine D-glycero-beta-D- hydrolase: -cysteine phosphomethylpyrimidine DACSA_RS07480 5-phosphate thiamine- synthase DACSA_RS16925 dehydrogenase: cys L-Ala- -D-Glu- 2-oxo-4-hydroxy- DACSA_RS09490 (deformylating): cobyrinate 4-phosphate 1,4-dihydroxy-2- desulfurase: LD- manno-heptose DACSA_RS16870 ligase: gshA kinase: thiD a 7,8-dihydrofolate synthase: phosphate kinase: adenylyltransferase SufS family DACSA_RS05360 DAP-D-Ala 4-carboxy-5- cob(I)yrinic acid a,c-diamide acyl-CoA DACSA_RS10840 dehydrogenase DACSA_RS14860 GTP naphthoyl-CoA adenosyltransferase: DACSA_RS16925 carboxypeptidase: 1-phosphate cobyrinate A,C- 2-methyl-6-phytyl- DACSA_RS12590 MoeB: moeB cysteine 6-phospho cysteine ureidoimidazoline thioesterase: adenylyltransferase: HMP-P PdxA: pdxA a carboxy- DACSA_RS04460 DACSA_RS15140 γ diamide synthase: 1,4-benzoquinol desulfurase: D-glucono- desulfurase: decarboxylase: uraD DACSA_RS13820 rfaE2 a very long- -L-glutamyl- 3-amino-1- 1-deoxy-D- adenylated a thiocarboxylated- CO cys a tRNA Cys DACSA_RS12730 bifunctional 5-(2-hydroxyethyl) thiamine diphosphate sufS GTP 3',8- 1,5-lactone DACSA_RS16925 chain alkane D-alanine hydroxyacetone xylulose 5- [small subunit of an [L-cysteine N-acetyl-β-D- L-alanyl-γ-D- (S)-(+)-allantoin ala [ThiS sulfur- UDP-N-acetyl-α-D- cob(II)yrinate hydroxymethylpyrimidine -4-methylthiazole 2-methyl-6-phytyl- cyclase 6-phosphogluconolactonase: SufS family adenosylcobinamide AMP a tetrahydrofolate 1-phosphate phosphate molybdopterin desulfurase]-S- 1,4-dihydroxy-2-naphthoate glucosamine-1,6- glutamyl-meso-2,6- triphosphate carrier protein] muramoyl-L-alanyl- (+)-7-epi- ADP-D-glycero-β- a,c-diamide kinase/ 1,4-benzoquinone MoaA: pgl cysteine D-ala methyltransferase: synthase] sulfanyl-L-cysteine moaA anhydro-N-acetyl- diaminopimeloyl- γ-D-glutamyl-meso- jasmonate D-manno-heptose phosphomethylpyrimidine δ pyridoxine 5'- desulfurase: DACSA_RS15250 -tocopherol (8S)-3',8-cyclo-7,8- bis(guanylyl molybdopterin) D-gluconate β-D-muramate D-alanine 2,6-diaminopimelate kinase: thiD phosphate sufS phylloquinol biosynthesis 4-methyl-5-(2- molybdopterin dihydroguanosine cofactor sulfurylation 6-phosphate an [L-cysteine LD- δ-tocopherol synthase: phosphooxyethyl) 2,3-dimethyl- 2-methyladeninyl adeninyl adenosylcobamide synthase 5'-triphosphate decarboxylating desulfurase]-S- carboxypeptidase: HMP-PP methyltransferase: adenosylcobamide biosynthesis DACSA_RS13305 a [DNA]-3'- a 5'-phospho- a mature dihomo γ- β-D-fructofuranose 1,4-dihydroxy- thiazole 6-phytyl-1,4- biosynthesis from sulfurtransferase: cyclic pyranopterin cys NADP(+)-dependent sulfanyl-L-cysteine DACSA_RS15140 cob(II)alamin NAD + H O a RNA-DNA hybrid DACSA_RS07485 1,6-anhydro-N- L-alanyl-γ-D- hydroxyl [DNA] peptidoglycan 2 1-phosphate a protein a protein 2-naphthoate benzoquinol from adenosylcobinamide-GDP adenosylcobinamide-GDP moeB monophosphate phosphogluconate ATP (n) linolenoyl-CoA β (meso-DAP thiamine phosphate β pyridoxine synthase cysteine acetyl- -muramate glutamyl-meso- ATP-dependent zinc ATP-dependent -tocopherol 2-methyladenine dehydrogenase: gnd containing) synthase: 5'-phosphate a thiocarboxylated MoaC: moaC desulfurase: anhydro-N- diaminopimelate NAD- fructose- metalloprotease Clp protease adenine D-ribulose a [TusA sulfur- acyl-CoA ribonuclease DACSA_RS06730 [small subunit of cyclic DACSA_RS16925 acetylmuramic Polymeric Compound cob(I)yrinic acid a,c-diamide dependent bisphosphate FtsH: hflB proteolytic: 2-carboxy-1,4- phytyl pyridoxamine 5-phosphate carrier protein]-S- thioesterase: HI: rnhA γ-tocopherol molybdopterin pyranopterin acid kinase: Degradation adenosyltransferase: DNA ligase membrane-bound aldolase ATP-dependent zinc DACSA_RS01690 naphthoquinone diphosphate 5'-phosphate SufS family sulfanyl-L-cysteine DACSA_RS09490 thiamine oxidase: pdxH synthase] phosphate cysteine ribulose-phosphate DACSA_RS10645 DACSA_RS04460 LigA: ligA lytic murein class II: fba metalloprotease DACSA_RS01695 γ-tocopherol ribose-5- glycogen degradation II acyl-CoA phosphate benzimidazolyl desulfurase: 3-epimerase: N-acetyl-D- cob(I)yrinic acid a,c-diamide transglycosylase: FtsH: hflB [+ 2 isozymes] 2-carboxy-1,4- methyltransferase: 2-methyladenine phosphate thioesterase: DNA a nucleoside 5'- adenosylcobamide biosynthesis PLP sufS DACSA_RS12965 muramate 6- adenosyltransferase: cobO DACSA_RS14850 a peptide a peptide naphthoquinone thiamine- DACSA_RS07485 adenosylcobinamide- ribotide phosphate isomerase a glycogen DACSA_RS13820 monophosphate from adenosylcobinamide-GDP adenine ribotide an [L-cysteine a [TusD sulfur- phosphate [DNA] NMN DHAP D-glyceraldehyde phytyltransferase: phosphate kinase: GDP RpiA: rpiA N-acetylmuramic AMP adenosylcobinamide- phosphate desulfurase]-S- D-xylulose carrier protein]-S- adenosylcobalamin a mature GlcNAc-1,6- DACSA_RS12590 α-tocopherol benzimidazole molybdopterin bis(guanylyl alpha-glucan γ DACSA_RS00560 GDP sulfanyl-L-cysteine sulfanyl-L-cysteine acid 6- triphosphate peptidoglycan anhMurNAc- di-homo- - molybdopterin) 5-phosphate D-ribose 5- family (n) thiamine adenosylcobinamide- 5-methylbenzimidazolyl cysteine phosphate γ linolenate cofactor phosphate phosphorylase: (meso-DAP L-Ala- -D-Glu- diphosphate GDP adenosylcobamide biosynthesis desulfurase: etherase: murQ demethylphylloquinone adenosylcobinamide- glgP containing) DAP-D-Ala ribazoletransferase: from adenosylcobinamide-GDP DACSA_RS16925 N-acetyl-D- benzimidazole DACSA_RS12905 GDP transketolase: tkt a [TusE sulfur glucosamine demethylphylloquinone folate transformations III (E. coli) ribazoletransferase: 5-methylbenzimidazole a [bis(guanylyl carrier protein]-S an α-limit dextrin adenosylcobinamide- ribotide NAD salvage pathway I (PNC VI cycle) a uridine 34 in tRNA 6-phosphate UDP-N-acetyl-α-D-muramoyl- RNase III mRNA dehydrogenase: molybdopterin) [bis-MGD di-trans,octa-cis- + an L-aspartyl- GDP Coα-[α-(2- DACSA_RS12905 D-sedoheptulose D-glyceraldehyde -sulfanylcysteine L-alanyl-γ-D-glutamyl-L- processing glu a (6S)-5- NADPH NAD a tRNA precursor a GGPP N-ethylglycine DACSA_RS06310 phosphate cofactor cofactor N-acetylglucosamine- 4-alpha- Asn a tetrahydrofolate methyladenin-9-yl)]-Co 7-phosphate 3-phosphate undecaprenyl phosphate formyltetrahydrofolate [tRNA ] + 6-phosphate glucanotransferase: lysyl-D-alanyl-D-alanine β Coα-[α-(adenin-9-yl)]- NAD chaperone]-S- chaperone]- tRNA 2- Asp-tRNA(Asn) demethylphylloquinol adenosylcobinamide- -adenosylcobamide deacetylase: nagA malQ Coβ-adenosylcobamide sulfanyl-L-cysteine bis-MGD thiouridine(34) NAD(P)(+) /Glu-tRNA(Gln) glycine GDP 5'-phosphate transaldolase: tal a debranched phospho-N- methionine 5'-phosphate adenosylcobinamide- 5-methylbenzimidazole synthase D-glucosamine ribonuclease bifunctional transhydrogenase ribonuclease D: amidotransferase oxidase ribazoletransferase: NAD+ synthase: α-limit dextrin acetylmuramoyl- synthase synthase: metH GDP ribotide phosphate MnmA: mnmA 6-phosphate III: rnc folylpolyglutamate (Re/Si-specific): DACSA_RS07655 subunit GatC: gatC ThiO: thiO DACSA_RS12905 DACSA_RS13225 D-erythrose pentapeptide- ChlG: chlG NAD+ synthase: F6P phosphoglucosamine ribonuclease synthase/ DACSA_RS04205 [+ 2 isozymes] Coα-[α-(2- sulfo-bis(guanylyl 4-phosphate glycogen transferase: an L-asparaginyl- adenosylcobinamide- DACSA_RS13225 dipyrromethane 34 mutase: III: rnc dihydrofolate DACSA_RS04210 phylloquinol serine Coα-[α- α α a 2-thiouridine Asn methyladenin-7-yl)]-Co Co -[ -(adenin-7-yl)]- nicotinate adenine cofactor biosynthesis molybdopterin) DACSA_RS00715 phosphorylase: DACSA_RS11465 synthase: [tRNA ] geranylgeranyl ethylamine glyoxylate a 7,8-dihydrofolatehydroxymethyltransferase:a 5-methyltetrahydrofolate (benzimidazolyl)]-Co β GDP NMN transketolase: tkt in tRNA DACSA_RS04215 a nucleoside 5'- β-adenosylcobamide Co -adenosylcobamide dinucleotide cofactor α glgP DACSA_RS00330 a tRNA glycine cleavage system β-adenosylcobamide ribazoletransferase: an apo-[hydroxymethylbilane -D-glucosamine D-glucopyranose RNase III monophosphate DACSA_RS14555 tRNA uridine-5- undecaprenyl-diphospho-N- an mRNA fragment protein GcvH: gcvH a (6S)-5-formyltetrahydrofolate 5'-phosphate adenosylcobalamin biosynthesis DACSA_RS12905 nicotinate-nucleotide synthase]-L-cysteine D-glyceraldehyde carboxymethylaminomethyl(34) 1-phosphate α-D- UMP processing bifunctional acetylmuramoyl-L-alanyl-γ-D- + [+ 2 isozymes] from adenosylcobinamide-GDP I adenylyltransferase: 3-phosphate synthesis enzyme MnmG: mnmG bifunctional UDP-N- glucopyranose mRNA a (6S)-5- NADH NADP thiamine diphosphate methylenetetrahydrofolate5-formyltetrahydrofolate Coα-[α-(5- glutamyl-L-lysyl- D-alanyl-D-alanine DACSA_RS13215 acetylglucosamine 1-phosphate glucokinase: formyltetrahydrofolate biosynthesis I (E. coli) dehydrogenase/ cyclo-ligase: S-adenosyl-L- 5,6-dimethylbenzimidazole methylbenzimidazolyl)]- a [hydroxymethylbilane tRNA uridine-5- methylenetetrahydrofolate methenyltetrahydrofolateDACSA_RS09265 Coα-[α- Coβ-adenosylcobamide synthase] ES intermediate carboxymethylaminomethyl(34) diphosphorylase/ DACSA_RS10535 2-[(2R,5Z)- methionine salvage II NaMN nicotinamide 2 alpha-D-glucose reductase: DACSA_RS13850 cyclohydrolase FolD: folD (benzimidazolyl)]-Co synthesis GTPase MnmE: mnmE glucosamine-1- α 2-carboxy-4- 5'-phosphate hydroxymethylbilane phosphate-specific UDP-N-acetyl- -D- (5Z,8Z,11Z,14Z,17Z) DNA with adenine:7,8- a [protein] N- a 5,10-methylenetetrahydrofolate a 5,10-methenyltetrahydrofolate β-adenosylcobamide phosphate N- di-trans,octa-cis- MoO - an L-glutamyl- GGPP acetyl-CoA synthase: hemC a 5-carboxymethylaminomethyl- muramoyl-L-alanyl-γ-D- 2 dihydro-8- terminal-formyl- chlorophyllide b methylthiazol-5(2H SAH acetyltransferase phosphoglucomutase: undecaprenyl phosphate GTP -icosapentaenoyl-CoA [tRNA Gln ] Glycolysis 2-thiouridine 34 in tRNA glutamyl-L-lysyl-D-alanine molybdopterin molybdopterin oxoguanine mismatch L-methionine acetyl-CoA )-ylidene]ethyl bifunctional α-ribazole a [hydroxymethylbilane GlmU: glmU DACSA_RS12025 Asp-tRNA(Asn) HMP-PP adenosylhomocysteinase: adenosylcobinamide- α α nicotinate cofactor carboxylase phosphate methylenetetrahydrofolate 5'-phosphate Co -[ -(5- synthase] ES intermediate protein S-nitrosylation N-acetyl-α-D- acyl-CoA /Glu-tRNA(Gln) DACSA_RS07400 GDP phosphoribosyltransferase: 3 glycolysis III (from glucose) peptide chlorophyll biotin dehydrogenase/ molybdenum methylbenzimidazolyl)]- and denitrosylation glucosamine phospho-N- thioesterase: A/G-specific amidotransferase glutathione L-homocysteine β DACSA_RS13210 hydroxymethylbilane molybdenum cofactor deformylase: synthase carboxylase thiamine phosphate folate polyglutamylation methenyltetrahydrofolate cofactor biosynthesis Co -adenosylcobamide a 5-aminomethyl-2- 1-phosphate acetylmuramoyl- DACSA_RS09490 adenine subunit GatC: gatC biosynthesis adenosylcobinamide- nicotinate synthase: hemC a [protein]- D-glucopyranose guanylyltransferase: def ChlG: chlG subunit: accC synthase: cyclohydrolase FolD: folD D-glucopyranose 34 pentapeptide- glycosylase: [+ 2 isozymes] GDP thiouridine in tRNA L-cysteine bifunctional UDP-N- 6-phosphate DACSA_RS17265 acyl-CoA DACSA_RS06730 methionine molybdopterin a [hydroxymethylbilane transferase: mutY an L-glutaminyl- [+ 3 isozymes] a tetrahydrofolate 10 ribazoletransferase: thioesterase: Gln an N -formyltetrahydrofolate cys glu synthase: metH molybdate synthase] ES intermediate glucokinase: acetylglucosamine DACSA_RS11465 [tRNA ] geranylgeranyl malonyl-CoA DACSA_RS12905 4 DACSA_RS13820 an N-terminal L- bis(guanylyl molybdenum NAD DACSA_RS10535 diphosphorylase/ bis(guanylyl formate thiamine hydroxymethylbilane glucosamine-1- an apurinic site methionyl-[protein] bifunctional serine met cofactor) biosynthesis phosphorylation and D-glucopyranose a 5-methylaminomethyl- a [protein] 3- undecaprenyl-diphospho-N molybdopterin) phosphate glutamate- adenosylcobalamin tetrahydrofolate salvage from synthase: hemC phosphate N- UMP adenine within DNA folylpolyglutamate hydroxymethyltransferase: molybdopterin MoO - transhydrogenation 6-phosphate 2-thiouridine 34 in tRNA nitrosothio- -acetylmuramoyl-L-alanyl-γ- cofactor (5Z,8Z,11Z,14Z,17Z) thiamine- -cysteine 5'-phosphate 2 5,10-methenyltetrahydrofolate a holo-[hydroxymethylbilane acetyltransferase coenzyme A synthase/ DACSA_RS14555 10 methionine molybdopterin + L-alanine D-glutamyl-L-lysyl- D-alanine -icosapentaenoate phosphate kinase: an N - menaquinol-7 biosynthesis ligase: gshA molybdate adenine molybdopterin NAD synthase] glucose-6- GlmU: glmU dihydrofolate formyltetrahydrofolate adenosyltransferase: dinucleotide cofactor NAD(+) kinase: a 5,10- phosphate DACSA_RS12590 DACSA_RS10315 UDP-N-acetyl- synthase: a 5,10- methenyltetrahydrofolate bis(guanylyl tungstenpterin) 6 bifunctional 1,4-dihydroxy- γ DACSA_RS04595 bifunctional isomerase: a 5-methylaminomethyl- α N -(3-methylbut- N-acetyl-D- an unstable thiamine DACSA_RS00330 methylenetetrahydrofolate -L-glutamyl- molybdenum cofactor -D-glucosamine (3E,5Z)-tetradeca- phosphoenol folylpolyglutamate 2-naphthoate molybdopterin NAD(+) kinase: methylenetetrahydrofolate cofactor biosynthesis DACSA_RS10390 2-(S-geranyl) 2-en-1-yl)- galactosamine sarcosine RecA filament- diphosphate L-cysteine SAM adenosylcobalamin guanylyltransferase: UDP-N-acetylglucosamine a sulfurated [sulfur carrier] ATP 3,5-dienoyl-CoA dGDP pyruvate 2'-deoxyadenosine bifunctional molybdotransferase 34 a [protein]- 37 a tRNA precursor synthase/ glutathione DACSA_RS07420 dehydrogenase/ F6P thiouridine in tRNA S-nitrosoglutathione 1-carboxyvinyltransferase: adenosine in tRNA 6-phosphate DNA complexDNA folylpolyglutamate MoeA: DACSA_RS17265 NADP + CTP a tetrahydrofolate dihydrofolate methenyltetrahydrofolate menaquinol-8 biosynthesis L-cysteine adenosine repair synthase/ demethylmenaquinol-7 synthase: DACSA_RS03790 bis(tungstenpterin) GTP murA acyl-CoA synthase: 10 cyclohydrolase FolD: folD S-(hydroxymethyl) N-acetylglucosamine- gshB bis(molybdenum NAD(P) an N - cofactor UDP-N-acetyl-α- tRNA (N6-isopentenyl thioesterase: deaminase: glycine oxidase protein dihydrofolate DACSA_RS00330 glutathione CCA tRNA pyruvate kinase: 6-phosphate bifunctional MoO - cofactor) transhydrogenase formyltetrahydrofolate demethylmenaquinol-8 a 5-methylaminomethyl- D-glucosamine- adenosine(37)-C2)- DACSA_RS09490 DACSA_RS13380 ThiO: thiO RecO: synthase: 10 2 nucleotidyltransferase: an N - glutathione menaquinol-6 biosynthesis menaquinol-9 biosynthesis β 2-(Se-phospho) dehydrogenase/ methylthiotransferase DACSA_RS11410 deacetylase: nagA recO DACSA_RS00330 demethylmenaquinone molybdopterin molybdenum cofactor subunit alpha: phosphoribosylglycinamide bifunctional molybdenum cofactor -D-fructose 1,6- enolpyruvate acyl-CoA a stabilized 34 class III alcohol DACSA_RS06020 [+ 2 isozymes] 2'-deoxyinosine formyltetrahydrofolate methyltransferase/2- cofactor guanylyltransferase: DACSA_RS04210 formyltransferase: demethylmenaquinone guanylyltransferase: bisphosphate selenouridine in tRNA UDP-N- MiaB: miaB RecA filament- menaquinol-4 biosynthesis I a 5,10- dehydrogenase: thioesterase: methoxy-6-polyprenyl- demethylmenaquinol-6 demethylmenaquinol-9 DACSA_RS17265 DACSA_RS05160 methyltransferase/2- DACSA_RS17265 acetylmuramate D-galactosamine DNA complex methylenetetrahydrofolate NADPH DACSA_RS14245 a tRNA DACSA_RS13820 acetate glyoxylate methylamine 1,4-benzoquinol bifunctional bifunctional bis(guanylyl methoxy-6-polyprenyl- fructose- dehydrogenase: N 6 -(3-methylbut-2-en- 6-phosphate demethylmenaquinol-4 a tetrahydrofolate an unsulfurated containing a pyruvate methylase UbiE: ubiE demethylmenaquinone demethylmenaquinone molybdopterin) 1,4-benzoquinol bis(guanylyl bisphosphate a 5-methylaminomethyl- S-(hydroxysulfenamide) murB 5'-deoxyadenosine 1-yl)-2-(methylsulfanyl) met dGTP bifunctional glutathione 37 [sulfur carrier] 3' CCA end (3E,5Z)- NADP methyltransferase/2- methyltransferase/2- cofactor methylase UbiE: ubiE tungstenpterin) cofactor aldolase class I: 2-selenouridine 34 UDP-N-acetyl- adenosine in tRNA coenzyme A demethylmenaquinone menaquinol-7 guanylyl molybdenum α tetradecadienoate biosynthesis methoxy-6-polyprenyl- methoxy-6-polyprenyl- menaquinol-8 DACSA_RS14035 in tRNA -D-muramate methyltransferase/2- cofactor biosynthesis 1,4-benzoquinol 1,4-benzoquinol Fatty Acid and Lipid Biosynthesis methoxy-6-polyprenyl- fructose- UDP-N- + MoO - methylase UbiE: ubiE methylase UbiE: ubiE a nascent peptidoglycan 2251 NAD 2 bisphosphate acetylmuramate:L- quinoxaline-2- phosphoenol guanosine a mismatched 1,4-benzoquinol molybdopterin menaquinol-6 palmitate biosynthesis hydroxylamine O-ureido-L- a phosphate NAD(+) kinase: menaquinol-9 octanoyl-[acyl-carrier aldolase alanyl-γ-D- (meso-DAP containing) aryl-carrier protein carboxyl adenylate adenine pyruvate asp in 23S rRNA DNA base pair methylase UbiE: ubiE cofactor molybdenum cofactor (type II fatty acid synthase) fatty acid elongation -- saturated acyl-CoA hydrolysis dADP homoserine monoester DACSA_RS04595 protein] biosynthesis class II: fba glutamyl-meso- PRPP 23S rRNA alkaline DNA menaquinol-4 guanylyltransferase: (guanosine(2251) mismatch NAD(+) kinase: (mitochondria, yeast) a 2,3,4-saturated diaminopimelate membrane-bound phosphatase: guanylyl DACSA_RS17265 -2'-O)- repair DACSA_RS07420 an acetoacetyl-[acp] an acetoacetyl-[acp] fatty acyl CoA ligase: lytic murein argininosuccinate DACSA_RS08495 + molybdenum acyl-CoA triose-phosphate acyl carrier adenine methyltransferase protein NADP an acetoacetyl-[acp] DACSA_RS06520 transglycosylase: pyruvate kinase: synthase: alkaline cofactor 3-oxoacyl-ACP 3-oxoacyl-ACP thioesterase: isomerase: ammonium protein: acpP phosphoribosyltransferase: RlmB: rlmB MutS: mutS DACSA_RS14850 DACSA_RS11410 DACSA_RS02040 2-O- phosphatase: a properly Other Biosynthesis reductase reductase DACSA_RS13820 DACSA_RS09975D-glyceraldehyde UDP-N-acetyl- DACSA_RS05445 DHAP Carboxylate Degradation [+ 2 isozymes] methylguanosine 2251 DACSA_RS20895 matched FabG: fabG FabG: fabG 3-phosphate α-D-muramoyl- acyl-CoA a mature peptidoglycan a nascent peptidoglycan a quinoxaline-2- in 23S rRNA an alcohol DNA base pair 3-oxoacyl-[acyl- 3-oxoacyl-[acyl- thioesterase: L-alanyl-γ-D- carboxyl-[aryl- canavaninosuccinate ophthalmate pyruvate decarboxylation to acetyl CoA I with (L-alanyl-γ-D-glutamyl- (meso-DAP containing) AMP carrier-protein] carrier-protein] a 3-oxoacyl-[acp] DACSA_RS09490 lipoprotein posttranslational modification glutamyl-meso-2,6- glycolate and carrier protein] pyruvate biosynthesis a 2,3,4-saturated meso-2,6-diaminopimeloyl- with GlcNAc terminus AMP dATP Calvin-Benson-Bassham cycle Carbohydrate Biosynthesis reductase: fabG reductase: fabG diaminopimelate glyoxylate UDP-N-acetyl-D- CMP-pseudaminate biosynthesis dTDP-β-L-rhamnose GDP-L-fucose a (3R)-3- 3-oxoacyl-[acyl- fatty acid a [pyruvate D-alanine) tetrapeptide 2-oxobutanoate a [prolipoprotein]- degradation II glucosamine biosynthesis I biosynthesis biosynthesis I (from a (3R)-3- hydroxybutanoyl-[acp] carrier-protein] 13-DPG dehydrogenase pyruvate L-cysteine 6 CO UDP-N-acetyl-α-D-glucosamine E2 protein] N pyruvate D-ribulose-1,5- 2 α-D-glucopyranose GDP-D-mannose) hydroxybutanoyl-[acp] 3-hydroxyacyl- reductase: fabG glycolate ribulose D-glucopyranose prolipoprotein -lipoyl-L-lysine a ring-opened 7- a 2'- 10 α phosphoglycerate dehydrogenase glycolate a guanine a [protein]-L- bisphosphate 6-phosphate 1-phosphate GDP- -D-mannose 3-hydroxyacyl- ACP dehydratase 3-oxoacyl-ACP diacylglyceryl 3-methylbutanoate a protein with glutathione fumarate carbonic acid (S)-2- bisphosphate glucose-6- glucose-1-phosphate kinase: pgk (acetyl- oxidase methylguanine deoxyribonucleoside [DNA] asp in tRNA methionine aminobutanoate carboxylase UDP-2-acetamido-2,6-dideoxy- GDP-mannose ACP dehydratase FabZ: fabZ beta-ketoacyl- reductase transferase: in DNA a disulfide bond 5'-triphosphate N2,N2- peptide- phosphate β thymidylyltransferase: transferring) subunit -L-arabino-hex-4-ulose alkane biosynthesis I 4,6-dehydratase: FabZ: fabZ ACP synthase FabG: fabG 3-phospho- DACSA_RS03780 glutamate- small subunit: isomerase: DACSA_RS03100 E1 component GlcD: glcD dimethylguanosine methionine UDP-4-amino-4, 6- α gmd a (2E)-but-2-enoyl-[acp] II: fabF D-glycerate a [prolipoprotein]- acetate- L-aspartate carbonic -cysteine DACSA_RS08860 DACSA_RS10390 dTDP- -D-glucose GDP-4-dehydro- a 2,3,4-saturated a (3R)-3-hydroxyacyl- subunit glyoxylate DNA- glutaredoxin group II tRNA (S)-S-oxide phosphoribulokinase: dideoxy-N-acetyl- a long-chain α a (2E)-but-2-enoyl-[acp] 2,3-bisphosphoglycerate- S-1,2-diacyl-sn- -CoA oxidase: anhydrase: ligase: gshA F6P dTDP-glucose 4,6- -D-rhamnose enoyl-ACP fatty acyl-[acp] [acyl-carrier protein] alpha: pdhA formamidopyrimidine 3: grxC intron reverse methyltransferase: reductase DACSA_RS00600 beta-L-altrosamine fatty acidlong-chain-fatty- 3-hydroxyacyl- independent glyceryl-L-cysteine ligase: acs nadB DACSA_RS16015 DACSA_RS08840 MsrA: msrA γ dehydratase: rfbB GDP-L-fucose enoyl-ACP reductase dihydrolipoyl glycosylase: transcriptase/ 2 -L-glutamyl-(S)- D-ribulose phosphoribulokinase: 3-phospho- transaminase: pseC ACP dehydratase phosphoglycerate a [pyruvate a [pyruvate glutaredoxin an N - a protein-L- ribose-5- glutamine-- acid--[acyl-carrier- synthase: dehydrogenase: 10 2-aminobutanoate 5-phosphate D-glycerate dTDP-4-dehydro-6- reductase FabI: fabI lipoprotein dehydrogenase dehydrogenase DACSA_RS05715 3: grxC maturase: ltrA dimethylguanine methionine- DACSA_RS08800phosphate fructose-6- UDP-4-amino-4,6-dideoxy- protein] ligase: DACSA_RS09220 FabZ: fabZ mutase: lpdA 3-methylbutanoyl- deoxy-α-D-glucopyranose FabI: fabI 6 6 [+ 25 isozymes] 2-iminosuccinate succinate in tRNA CO H O (S)-S-oxide glutathione N-acetyl-β-L-altrosamine DACSA_RS18090 signal peptidase: E2 protein] N E2 protein] N -S- diphosphate 2 2 isomerase phosphate a long-chainDACSA_RS11995 GDP-4-dehydro-6- a butanoyl-[acp] (S)-malate a [DNA]- 2,6-diamino-4- AMP CoA synthase: UDP-4-amino-4, 6- dTDP-4- β DACSA_RS04335 -dihydrolipoyl- acetyldihydrolipoyl- a 5'-phospho- a protein with RpiA: rpiA transaminase fatty acyl-[acyl- deoxy- -L-galactose a butanoyl-[acp] 2-phospho- nucleotide- hydroxy-5-(N-methyl) 4-oxo-2-pentenal GSSG gshB D-ribose 5- phosphoglycerate dideoxy-N-acetyl- dehydrorhamnose L-lysine lipoate L-lysine [DNA] reduced L- ribulose-phosphate (isomerizing) carrier protein] GDP-L-fucose beta-ketoacyl- D-glycerate an (S-diacyl- 3'-phosphate formamidopyrimidine [DNA] phosphate kinase: pgk beta-L-altrosamine 3,5-epimerase: rfbC a lipoprotein acetyltransferase: cysteine residues ophthalmate 3-epimerase: : glmS glycogen biosynthesis I (from ADP-D-Glucose) long-chain acyl- synthase: beta-ketoacyl- ACP synthase phosphopyruvate sn-glyceryl) N-acetyltransferase: dTDP-4-dehydro- II: fabF signal peptide lpdA DACSA_RS12965 transketolase: tkt D-glucosamine [acyl-carrier- β DACSA_RS09220 ACP synthase a 2,3,4-saturated enoyl-ACP a trans-2-enoyl- hydratase: -L-cysteinyl- D-xylulose pseH -L-rhamnose signal acetate 13-DPG 6-phosphate D-glucopyranose 6-phosphate protein] reductase: II: fabF fatty acyl-[acp] reductase [acyl-carrier protein] DACSA_RS09035 [apolipoprotein] a 7,8-dihydro- a 2'- an [amino-group carrier β conversion + a negatively 5-phosphate D-sedoheptulose UDP-2,4-diacetamido-2,4,6- dTDP-4- GDP- -L-fucose a 3-oxohexanoyl-[acp] peptide a ferrocytochrome stearoyl-CoA menadione NADH H γ α-amylose phosphoglucosamine DACSA_RS10850 FabI: fabI phosphoenol 8-oxoguanine deoxyribonucleoside [DNA] supercoiled DNA protein]-C-terminal- - 3',5'-ADP 7-phosphate trideoxy-β-L-altropyranose alpha-D-glucose dehydrorhamnose a 3-oxohexanoyl-[acp] apolipoprotein N- peptidase to acetyl-CoA b glyceraldehyde- mutase: a long-chain pyruvate in DNA 5 5'-triphosphate DNA topoisomerase (L-glutamyl)-L-glutamate 1,4-alpha-glucan 3'(2'),5'- transketolase: tkt sedoheptulose UDP-2,4-diacetamido- phosphate-specific reductase: rfbD 3-oxoacyl-ACP acyltransferase: lnt SppA: sppA acetate 3-phosphate DACSA_RS00715 fatty aldehyde acetyl-CoA 4 subunit A: acetylglutamate branching bisphosphate bisphosphatase: 2,4, 6-trideoxy-beta- phosphoglucomutase: β 3-oxoacyl-ACP reductase enoyl-ACP pyruvate kinase: an N-acyl-(S- acetate- NADH-quinone dehydrogenase: α-D-glucosamine dTDP- -L-rhamnose signal DNA- acyl-CoA DNA DACSA_RS07760 kinase: argB protein GlgB: glgB nucleotidase: glpX L-altropyranose DACSA_RS12025 aldehyde reductase FabG: fabG reductase DACSA_RS11410 diacyl-sn-glyceryl) -CoA : DACSA_RS06525 1-phosphate peptide formamidopyrimidine desaturase: polymerase type I DNA 1,4-alpha-glucan- DACSA_RS04730 D-sedoheptulose hydrolase: pseG α oxygenase FabG: fabG 3-oxoacyl-[acyl- FabI: fabI [+ 2 isozymes] -L-cysteinyl- ligase: acs nuoH an [amino-group carrier -D-glucopyranose peptidase glycosylase: DACSA_RS04270 III subunit topoisomerase: branching protein: 1,7-bisphosphate D-glyceraldehyde bifunctional UDP-N- 2,4-diacetamido-2,4,6- (deformylating): heptadecane biosynthesis 3-oxoacyl-[acyl- carrier-protein] [lipoprotein] acetyl-CoA DACSA_RS12520 protein]-C-terminal- F6P 1-phosphate pyruvate SppA: sppA Nucleoside and Nucleotide Degradation DACSA_RS05715 delta: holA topA γ DACSA_RS03145 AMP 3-phosphate acetylglucosamine trideoxy-β-L-altropyranose DACSA_RS10840 carrier-protein] reductase: fabG nuoK -(5-phospho-L- fructose- diphosphorylase/ glucose-1-phosphate [+ 2 isozymes] a relaxed DNA glutamyl)-L-glutamate amylopectin fructose 1,6- a long-chain alkane stearate reductase: fabG a (3R)-3- a peptide a ferricytochrome bisphosphate glucosamine-1- adenylyltransferase: adenosine a [DNA]- oleoyl-CoA bisphosphatase: triose-phosphate stearate--[acyl-carrier- hydroxyhexanoyl-[acp] gondoate biosynthesis UTP and CTP dephosphorylation I a 5'-phospho- 7,8-dihydro- b phosphate N- DACSA_RS04470 a (3R)-3- 4-oxo-2-pentenal 5 + aldolase protein] ligase: (anaerobic) tRNA processing nucleotide- [DNA] 8-oxoguanine NAD menadiol DACSA_RS13600 class II: fba isomerase: acetyltransferase pseudaminate hydroxyhexanoyl-[acp] 3-hydroxyacyl- 3'-phosphate [DNA] a (1->4)-α-D-glucan ADP-α-D-glucose DACSA_RS11995 degradation II UTP [+ 2 isozymes] DACSA_RS09975 GlmU: glmU 3-hydroxyacyl- ACP dehydratase NADH repair (prokaryotes) a stearoyl-[acp] a malonyl-[acp] an oleoyl-[acp] a polycistronic β N-acetyl-α-D- glycogen ACP dehydratase FabZ: fabZ -D-fructose 1,6- UDP-α-D- tRNA precursor AMP CTP synthase: DHAP glucosamine synthase FabZ: fabZ NADH adenine 2503 D-ribulose-1,5- a 2'- a protein-L- bisphosphate CMP-pseudaminate galactose long-chain acyl- a (2E)-hex-2-enoyl-[acp] 5'/3'-nucleotidase DACSA_RS17350 an acyl-[acyl- canavaninosuccinate DHAP 1-phosphate GlgA: glgA in 23S rRNA bisphosphate deoxyribonucleoside met methionine- biosynthesis [acyl-carrier- beta-ketoacyl- SurE: surE carrier protein] [DNA] α a (2E)-hex-2-enoyl-[acp] UDP 5'-triphosphate NAD(P)H- (R)-S-oxide bifunctional UDP-N- a (1->4)- -D-glucan UDP-α-D-glucose protein] reductase: enoyl-ACP ACP synthase 5'/3'-nucleotidase CTP bifunctional peptide- acetylglucosamine dependent glycerol- ornithine UDP-glucose DACSA_RS10850 reductase II: fabF a tRNA precursor a tRNA precursor with SurE: surE 23S rRNA ribulose methionine fructose- diphosphorylase/ 1,4-alpha-glucan- enoyl-ACP adenosine phosphate DNA argininosuccinate 3-phosphate acetyltransferase/ PRPP biosynthesis 4-epimerase FabI: fabI with a 5' extension a 5' extension and (adenine(2503)-C(2) bisphosphate (R)-S-oxide bisphosphate glucosamine-1- branching protein: octadecanal reductase acyltransferase polymerase lyase: argH dehydrogenase: N-acetylglutamate GalE: galE (R)-NADHX and a long 3' trailer a short 3' extension UMP )-methyltransferase carboxylase reductase D-ribose 5- aldolase class I: phosphate N- DACSA_RS03145 FabI: fabI an (11Z)-3-oxo- bifunctional adenosine CDP PlsX: plsX III subunit DACSA_RS00500 synthase: argJ UDP-α-D-galactose a hexanoyl-[acp] ribonuclease P RlmN: rlmN small subunit: MsrB: msrB phosphate DACSA_RS14035 acetyltransferase 1,4-alpha-glucan aldehyde oxygenase icos-11-enoyl-[acp] ADP-dependent ribonuclease D: deaminase: 5'/3'- delta: holA sn-glycerol N-acetyl-L- a [protein]-L- ribose-phosphate (deformylating): a hexanoyl-[acp] DACSA_RS07655 protein component: DACSA_RS08860 3-phosphate fructose- GlmU: glmU branching beta-ketoacyl- 3-oxoacyl-[acyl- NAD(P)H-hydrate ribonuclease D: DACSA_RS13380 nucleotidase [+ 2 isozymes] L-canavanine fumarate methionine methionine pyrophosphokinase: protein GlgB: glgB DACSA_RS10840 DACSA_RS10200 SurE: surE a 2-methyladenine 2503 bisphosphate UDP-N-acetyl- beta-ketoacyl- ACP synthase carrier-protein] dehydratase/ DACSA_RS07655 5'-deoxyadenosine acyl-carrier protein an acyl phosphate DACSA_RS06110 CMP in 23S rRNA met 3-phospho- aldolase α-D-glucosamine ACP synthase II: fabF reductase: fabG NAD(P)H-hydrate a tRNA precursor with inosine 5'/3'- 2-phosphoglycolate PRPP a glycogen heptadecane D-glycerate class II: fba II: fabF 3-oxoacyl-ACP epimerase: a short 3' extension 5'/3'- nucleotidase [DNA] a 3-oxooctanoyl-[acp] DACSA_RS09280 SurE: surE reductase (S)-NADHX a tRNA precursor nucleotidase a 3-oxooctanoyl-[acp] 3-oxoacyl-ACP FabG: fabG with a 5' extension SurE: surE uridine ribonuclease D: a double-stranded an L-1- (3R,5S)-3- reductase a (3R,11Z)-3-hydroxy- bifunctional 5'/3'- an N-terminal an L-phenylalanyl- 2-methylbutanoate an adenosine 37 a peptide with a a (1->4)-α-D-glucan 3-oxoacyl-ACP DACSA_RS07655 DMAPP oligonucleotide phosphatidyl- hydroxy-1- FabG: fabG icos-11-enoyl-[acp] ADP-dependent nucleotidase arginyl-[protein] [tRNA Phe ] leader sequence reductase ribonuclease P in tRNA 1,4-alpha-glucan- bifunctional sn-glycerol pyrroline-5- glucosylglycerol biosynthesis NAD(P)H-hydrate hypoxanthine SurE: surE FabG: fabG 3-oxoacyl-[acyl- 3-hydroxyacyl- protein component: branching protein: oligoribonuclease/ carboxylate dehydratase/ 5'-deoxyadenosine acetate- lipid kinase: pyrroline-5- carrier-protein] ACP dehydratase DACSA_RS10200 cytidine leucyl/phenylalanyl- tRNA (adenosine(37)-N6) DACSA_RS03145 PAP phosphatase 3-oxoacyl-[acyl- D-glucopyranose NAD(P)H-hydrate degradation I -CoA signal DACSA_RS07935 carboxylate peptidoglycan biosynthesis I (meso-diaminopimelate containing) Cell Structure Biosynthesis Polyprenyl Biosynthesis reductase: fabG FabZ: fabZ 5-(methoxycarbonylmethoxy) tRNA--protein -dimethylallyltransferase 1,4-alpha-glucan NrnA: lipid IV biosynthesis (E. coli) carrier-protein] 6-phosphate epimerase: ligase: acs peptidase I: lepB 1-(3-sn- reductase: A uridine biosynthesis transferase: branching DACSA_RS05600 reductase: fabG a (3R)-3- a (2E,11Z)-icosa- DACSA_RS09280 MiaA: miaA signal phosphatidyl) proC UDP-N-acetyl- alpha-D-glucose 5'-deoxyadenosine DACSA_RS12680 protein GlgB: glgB a nucleoside 5'- Peptide RS02645 Peptide α a (3R)-3- trans, trans-farnesyl hydroxyoctanoyl-[acp] 2,11-dienoyl-[acp] -sn-glycerol Hyp -D-glucosamine di-trans,poly-cis-undecaprenyl a (3R)-3- phosphate-specific xanthine (2S)-2- peptidase I: lepB a (1,6)-α-D-glucosyl- monophosphate hydroxytetradecanoyl- UDP-N-acetyl- diphosphate NADH an uncharged tRNA SAM S-methyl-5'- N 6 -(3-methylbut- UDP-N-acetylglucosamine phosphate biosynthesis hydroxyoctanoyl-[acp] 3-hydroxyacyl- enoyl-ACP phosphoglucomutase: prephenate methylbutanoyl- diphosphate (1,4)-α-glucan 3-phosphate [acp] α-D-glucosamine biosynthesis DHAP thioadenosine L-phenylalanyl-L- AMP 2-en-1-yl)- 1-carboxyvinyltransferase: ACP dehydratase reductase DACSA_RS12025 Phe CoA 3-hydroxyacyl- phosphorylase: arginyl-[protein] a tRNA adenosine 37 Zn 2+ Zn 2+ murA (2E,6E)-farnesyl FabZ: fabZ FabI: fabI α-D- a leader sequence a peptide RS12530 acyl-ACP--UDP-N- IPP ACP dehydratase NAD(P)H- 2+ 2+ α diphosphate DACSA_RS08380 in tRNA Mn Mn UDP-N-acetyl- - acetylglucosamine O- isoprenyl FabZ: fabZ dependent glycerol- glucopyranose a (2E)-oct-2-enoyl-[acp] a gondoyl-[acp] urate α D-glucosamine- acyltransferase: lpxA transferase: 3-phosphate 1-phosphate a 5- S-adenosyl-S- 5-deoxy- -D- enolpyruvate di-trans,octa-cisDACSA_RS04110 geranyl diphosphate a (2E)-oct-2-enoyl-[acp] dehydrogenase: glucose-1-phosphate hydroxyuridine 34 carboxymethyl- ribose 1-phosphate DMAPP enoyl-ACP an N-terminal an L-phenylalanyl- a (1->4)-α-D-glucan (2R,3S)-2- an oxidized (7R,8S)- 3+ 3+ UDP-3-O-[(3R)-3- -undecaprenyl adenylyltransferase: H O carbamoyl Fe RS15455 Fe UDP-N- biosynthesis reductase DACSA_RS00500 in tRNA L-homocysteine DL-allothreonine 2 L-ornithine L-lysyl-[protein] [tRNA Phe ] GTP phosphate methylisocitrate factor 420 diaminononanoate acetylmuramate hydroxymyristoyl]-N- prenyltransferase diphosphate enoyl-ACP FabI: fabI DACSA_RS04470 1,4-alpha-glucan- bifunctional coenzyme ATP- α undecaprenyl- reductase sn-glycerol branching protein: dehydrogenase: acetyl- -D-glucosamine UbiA: IPP α tRNA 5- aconitate F420-reducing dependent diphosphate 3-phosphate ADP- -D-glucose murB UDP-3-O-acyl-N- DACSA_RS04785 prenyltransferase FabI: fabI an octanoyl-[acp] methoxyuridine(34) 5-deoxy-D-ribulose leucyl/phenylalanyl- serine ornithine DACSA_RS03145 hydratase 2/2- hydrogenase dethiobiotin acetylglucosamine phosphatase: 1-phosphate GTPase Era: Ca 2+ RS04170 Ca 2+ ala UDP-N-acetyl- geranyl UbiA: Metabolic Regulator /uridine 5-oxyacetic tRNA--protein hydroxymethyltransferase: carbamoyltransferase: 1,4-alpha-glucan methylisocitrate subunit beta: synthetase α deacetylase: DACSA_RS15300 an octanoyl-[acp] glucosylglycerol- DACSA_RS01290 -D-muramate diphosphate DACSA_RS04785 acid(34) synthase transferase: DACSA_RS14555 argF branching dehydratase: acnB DACSA_RS12450 BioD: bioD glu DACSA_RS14795 di-trans,octa-cis geranyl Biosynthesis phosphate [+ 4 isozymes] cis-2- a reduced -undecaprenyl CmoB: cmoB DACSA_RS12680 protein GlgB: glgB dethiobiotin UDP-N- UDP-3-O-(3- prenyltransferase diphosphate beta-ketoacyl- synthase: ggpS methylaconitate factor 420 phosphate ppGpp metabolism starch glutamate hydroxymyristoyl) UbiA: ACP synthase + 2+ 2+ acetylmuramate-- a 5-(carboxymethoxy) H Mg RS09545 Mg α II: fabF oleate biosynthesis 2-O-(α-D- pyrimidine deoxyribonucleotides L-phenylalanyl- acetaldehyde gly phosphate L-citrulline L-alanine ligase: racemase: - -D-glucosamine DACSA_RS04785 34 acetaldehyde DHAP Phe GDP III () uridine in tRNA dephosphorylation L-lysyl-[protein] a tRNA DACSA_RS06520 DACSA_RS09235 UDP-3-O-(3- (2E,6E)-farnesyl pppGpp glucopyranosyl) a 3-oxodecanoyl-[acp] -sn-glycerol nucleoside triphosphate hydroxymyristoyl) diphosphate sn-glycerol UDP-N-acetyl-α-D- D-glt glucosamine N- bifunctional (p)ppGpp a stearoyl-[acp] 3-phosphate pyrophosphohydrolase: 2+ 2+ 3-phosphate Ni RS15690 Ni synthetase/guanosine- guanosine 3'- 3-oxoacyl-ACP mazG an N-formyl-L- a peptidoglycan a peptide with UDP-N-acetyl- a [lipoyl-carrier muramoyl-L-alanine acyltransferase: glucosylglycerol 3- a 5-(methoxycarbonylmethoxy) a purine base a (1->4)-α-D-glucan all-trans 3',5'-bis(diphosphate) 3'- reductase dCTP dCMP methionylaminoacyl- dimer (generic) an N-terminal α-D-glucosamine protein]-N 6 -[(R) lpxD diphosphate 5'- phosphatase: stpA uridine 34 in tRNA S-methyl-5'- lesion in DNA neurosporene pyrophosphohydrolase: FabG: fabG glycerol-3- 1,4-alpha-glucan- UDP-N- UDP-N- UDP-2-N,3-O-bis[(3R)- triphosphate 3'- 2-O-(α-D- thioadenosine tRNA Xaa-L-proline -dihydrolipoyl]- 9,9'-di- acetylmuramoyl- 3-hydroxytetradecanoyl]- DACSA_RS05935 diphosphatase: 3-oxoacyl-[acyl- phosphate 1-O- nucleoside triphosphate degradation II branching protein: acetylglucosamine L-lysine cis-zeta- glucopyranosyl) DNA- membrane-bound dihydrolipoyl a purine RS02175 a purine L-alanine--D- α-D-glucosamine DACSA_RS05935 carrier-protein] acyltransferase pyrophosphohydrolase: S-methyl-5'- DACSA_RS03145 2-epimerase (non- carotene glycerol formamidopyrimidine peptide lytic murein leucyl dehydrogenase: glutamate ligase: lipid IV biosynthesis (P. putida) reductase: fabG PlsY: plsY mazG thioadenosine 1,4-alpha-glucan hydrolyzing): desaturase: A queuosine biosynthesis I (de novo) S-methyl-5'- deformylase: transglycosylase: aminopeptidase: lpdA 6 37 dUTP dUMP glycosylase: DACSA_RS04115 a [lipoyl-carrier DACSA_RS03495 N -L-threonylcarbamoyladenosine def DACSA_RS12440 branching α zds a (3R)-3- thioadenosine DACSA_RS14850 UDP-N-acetyl- - 6 a (3R)-3- GTP ppGpp 1-stearoyl- DACSA_RS05715 protein GlgB: glgB protein]-N -[(R hydroxydecanoyl-[acp] -modified tRNA biosynthesis phosphorylase: D-mannosamine all-trans-lycopene UDP-N-acetyl- hydroxydecanoyl- UDP-N-acetyl- lipid X peptidoglycan maturation (meso-diaminopimelate containing) sn-glycerol preQ )-lipoyl]-L-lysine 0 DACSA_RS08380 a peptide with a GlgE-glycogen meso-diaminopimelate α [acp] α-D-glucosamine 3-hydroxyacyl- 3-phosphate NADPH-dependent 7- 5-hydroxy-CTP 5-hydroxy-CMP a [DNA]- a L-methionylaminoacyl- GlcNAc-1,6- -D-muramoyl-L- biotin-carboxyl carrier thr a 5'-phospho- a modified formate a lipid II a proteinogenic an N-terminal lipid-A- lipid II (meso nucleoside- ACP dehydratase 1-acyl-sn-glycerol- cyano-7-deazaguanine 5-MTR-1-P nucleotide- 4-oxo-2-pentenal tRNA anhydro-MurNAc- alanyl-D-glutamate protein assembly [DNA] nucleobase amino acid L-proline acyl-ACP--UDP-N- disaccharide diaminopimelate containing) diphosphate kinase: GDP FabZ: fabZ 3-phosphate threonylcarbamoyl- reductase QueF: queF 3'-phosphate pentapeptide acetylglucosamine O- synthase: lpxB bifunctional (p)ppGpp acyltransferase: a [biotin carboxyl- AMP synthase: preQ UDP-N- peptidoglycan DACSA_RS03410 pyrophosphokinase: 1 acyltransferase: lpxA lipid A disaccharide : DACSA_RS05935 synthetase/guanosine- a (2E)-dec-2-enoyl-[acp] DACSA_RS06460 carrier protein]-L-lysine DACSA_RS00635 acetylmuramoyl- a methylated 46 (E. coli) DACSA_RS01300 3',5'-bis(diphosphate) 3'- [+ 2 isozymes] biotin--[acetyl-CoA- L-threonylcarbamoyladenylate tRNA guanosine(34) a ferrocytochrome palmitoyl-CoA an (S)-2- an N-modified a [release factor]- a guanine cyclic-AMP 9,9'-di-cis- L-alanyl-D- 2-oxoglutarate nucleobase ζ UDP-3-O-[(3R)-3- pyrophosphohydrolase: enoyl-ACP a 1-stearoyl 2- synthase: DACSA_RS01125 transglycosylase Tgt: tgt b halocarboxylate aminoacyl-[tRNA] L-glutamine in tRNA -carotene glutamate--2, 6- a nascent peptidoglycan carboxylase] ligase: (L-threonylcarbamoyl) 5 within DNA peptide chain tRNA 9,9'-di- hydroxydecanoyl]- γ DACSA_RS05935 reductase acyl-sn-glycerol 3',5'-cyclic-AMP diaminopimelate with (L-alanyl- -D-glutamyl- DACSA_RS08945 adenylate a 7-aminomethyl-7- release factor (guanosine(46)-N7) cis-zeta- D-ala N-acetyl-α-D- FabI: fabI 3-phosphate phosphodiesterase: ligase: meso-2,6-diaminopimeloyl-D- GDP a [biotin carboxyl- deazaguanosine 34 in tRNA Carbohydrate Degradation HAD family glucosamine lipid IV (E. coli) tRNA (adenosine(37)-N6)- acyl-CoA alpha-ketoglutarate- aminoacyl-tRNA N(5)-glutamine -methyltransferase cpdA carotene DACSA_RS16850 A alanyl-D-alanine) pentapeptide carrier protein]-N hydrolase: threonylcarbamoyltransferase tRNA preQ1(34) S- dependent methyltransferase: 7 TrmB: trmB desaturase: D-alanine--D- UDP-3-O-acyl-N- a decanoyl-[acyl-carrier protein] 6 desaturase: hydrolase: an N - -biotinyl-L-lysine D-galactose degradation I (Leloir pathway) DACSA_RS15105 acetylglucosamine complex dimerization adenosylmethionine DACSA_RS04270 dioxygenase AlkB: DACSA_RS16870 prmC 46 zds alanine ligase: UDP-N-acetyl-α-D- D-alanyl-D-alanine penicillin-binding a 1-oleoyl 2- 5 methylguanine AMP beta-ketoacyl- subunit type 1 TsaB: tsaB ribosyltransferase- DACSA_RS17260 [+ 4 isozymes] a [release factor]-N DACSA_RS15175 muramoyl-L-alanyl- deacetylase: carboxypeptidase/ protein 2: acyl-sn-glycerol β-D- in tRNA prolycopene ACP synthase [+ 2 isozymes] isomerase QueA: queA -methyl-L-glutamine γ-D-glutamyl-meso- DACSA_RS14795 D-alanyl-D-alanine- DACSA_RS10090 a mature peptidoglycan with 3-phosphate galactopyranose D-alanyl-D-alanine UDP-3-O-(3- II: fabF a [biotin carboxyl- an N 6 -L- palmitoleoyl-CoA a ferricytochrome a nucleobase a (2R)-2- an N-modified an uncharged γ 34 2,6-diaminopimelate endopeptidase: dacB [+ 2 isozymes] (L-alanyl- -D-glutamyl-meso- carrier-]- 37 an epoxyqueuosine in tRNA galactose b formaldehyde succinate a halide anion amino acid tRNA hydroxydecanoyl) threonylcarbamoyladenine 5 within DNA hydroxy fatty acid α penicillin-binding 2,6-diaminopimeloyl-D-alanyl- N 6 -biotinyl-L-lysine mutarotase: - -D-glucosamine a nascent peptidoglycan a 3-oxododecanoyl-[acp] in tRNA tRNA UDP-N- UDP-3-O-(3- protein 2: mrdA D-alanine) pentapeptide acetyl-CoA DACSA_RS14620 acetylmuramoyl- with D,D cross-links (meso- acetyl-CoA epoxyqueuosine(34) α 3-oxoacyl-ACP carboxylase -D- 34 a thiocarboxylated a β-Gal-(1->3)-α-Gal-(1->2) 37 hydroxymyristoyl) diaminopimelate containing) carboxylase, reductase QueG: queG a uridine an (R)-2- adenosylcobinamide a guanine an unfolded tripeptide--D- glucosamine N- a nascent peptidoglycan reductase biotin galactopyranose ala a pimeloyl-[acp] [SAMP] C- halocarboxylate -[α-(1->6)-oligomannan] in tRNA L-threonine 3- γ carboxyltransferase in tRNA protein alanyl-D- alanine with (L-alanyl- -D-glutamyl- FabG: fabG carboxylase 34 terminal glycine bifunctional polysaccharide tRNA O-phosphate acyltransferase: subunit beta: accD N-end rule pathway I (prokaryotic) a queuosine in tRNA threonine- chaperonin ligase: murF meso-2,6-diaminopimeloyl- subunit: accC adenosylcobinamide pyruvyl (guanosine(37)-N1) lpxD 3-oxoacyl-[acyl- HAD family phosphate GroEL: groL D-alanine) tetrapeptide a mature peptidoglycan a [carboxyl-carrier leucyl/phenylalanyl- tRNA 2- kinase/ transferase -methyltransferase α UDP-2-N-[(3R)-3- carrier-protein] α-D-galactose 8-amino-7- hydrolase: decarboxylase: chaperonin UDP-N-acetyl- -D- with D,D cross-links (meso- 6 tRNA--protein UDP-α-D-glucose thiouridine(34) adenosylcobinamide- CsaB: csaB TrmD: trmD hydroxydodecanoyl]- reductase: fabG protein dimer]-N - 1-phosphate oxononanoate a 4,6-CH (COO-)C-β- an N 1 - GroEL: groL muramoyl-L-alanyl- LD-carboxypeptidase: transferase: DACSA_RS15105 phosphate 3 (R)-1-amino-DACSA_RS03060 3-O-[(3R)-3- diaminopimelate containing) carboxybiotinyl-L-lysine synthase: bioF synthase α 37 γ-D-glutamyl-meso- DACSA_RS15140 a (3R)-3- DACSA_RS12680 a [protein] [+ 4 isozymes] Gal-(1->3)- -Gal-(1->2) methylguanine 2-propanol O a protein hydroxydecanoyl]- an N-terminal MnmA: mnmA guanylyltransferase: α 2,6-diaminopimeloyl- di-trans,octa-cis- a nascent peptidoglycan a nascent peptidoglycan a mature peptidoglycan hydroxydodecanoyl-[acp] N-terminal L- -[ -(1->6)-oligomannan] in tRNA -2-phosphate α-D-glucosamine arginyl-[protein] cobU D-alanyl-D-alanine undecaprenyl phosphate with L,D cross links (meso- a nascent peptidoglycan with with (L-alanyl-γ-D-glutamyl- with (L-alanyl-γ-D-glutamyl- leucyl-L-arginine (8S)-8-amino-7- γ 3-hydroxyacyl- a [SAMP] C- a 2-thiouridine 34 a (2R)-2- adenosyl-cobinamide diaminopimelate containing) (L-alanyl- -D-glutamyl-meso- meso-2,6-diaminopimeloyl- meso-2,6-diaminopimeloyl- oxononanoate acyl-carrier protein a halide anion 2,6-diaminopimelate) tripeptide ACP dehydratase UDP- terminal glycine in tRNA hydroxy fatty acid phosphate phospho-N- glycine) tetrapeptide D-alanine) tetrapeptide FabZ: fabZ leucyl/phenylalanyl- glucose 4- acetylmuramoyl- fatty acid biosynthesis tRNA--protein epimerase pentapeptide- lipid X (P. putida) a mature peptidoglycan a (2E)-dodec-2-enoyl-[acp] initiation (type II) transferase: GalE: galE UDP-N-acetyl- decaprenyl-diphospho-N- an (R)-2- a cytidine 1402 guanine 37 transferase: a mature peptidoglycan with a [protein] α an acyl-CoA H O histidinol lipid-A- with L,D cross-links (meso- a mature peptidoglycan an N-terminal DACSA_RS12680 -D-glucosamine acetylmuramoyl-pentapeptide halocarboxylate 2 a type IV prepilin in 16S rRNA in tRNA Phe his DACSA_RS11465 γ N-terminal L- disaccharide diaminopimelate containing) (L-alanyl- -D-glutamyl-meso- with (L-alanyl-γ-D-glutamyl- enoyl-ACP acetyl-CoA L-lysyl-[protein] 16S rRNA tRNA histidinol leucyl-L-lysine L-histidine N(alpha) synthase: lpxB 2,6-diaminopimelate) tripeptide meso-2,6-diaminopimeloyl- reductase acetyl-CoA undecaprenyldiphospho- (cytidine(1402)-2'-O) (guanosine(37)-N1) dehydrogenase: undecaprenyldiphospho- HAD family acyl-CoA thioesterase: -methyltransferase: lipid A glycine) tetrapeptide FabI: fabI carboxylase, α-D- muramoylpentapeptide beta-N- -methyltransferase: -methyltransferase hisD N-acetylmuramoyl-L- UDP-α-D- hydrolase: DACSA_RS09490 prepilin peptidase: egtD disaccharide carboxyltransferase glucopyranose acetylglucosaminyltransferase: rsmI 1 TrmD: trmD alanyl-γ-D-glutamyl-meso a dodecanoyl-[acp] galactose DACSA_RS15105 acyl-CoA thioesterase: DACSA_RS09910 a 2'-O- an N - (P. putida) subunit beta: accD 1-phosphate murG 1402 37 his -2,6-diaminopimeloyl- [+ 4 isozymes] DACSA_RS13820 methylcytidine methylguanine hercynine malonyl-CoA Phe D-alanyl-D-alanine alpha-D-glucose in 16S rRNA in tRNA L-histidine biosynthesis Amino Acid Biosynthesis decaprenyl-pyrophosphoryl- undecaprenyldiphospho- L-isoleucine biosynthesis II L-arginine biosynthesis II (acetyl cycle) superpathway of L- beta-ketoacyl- ACP S- phosphate-specific UDP a cleaved type lipid IV L-valine biosynthesis L-proline (N-acetylglucosamine)-N- an (S)-2- a peptide muramoylpentapeptide beta-N- A ACP synthase a halide anion a carboxylate threonine biosynthesis biosynthesis I malonyltransferase: phosphoglucomutase: hydroxycarboxylate IV prepilin acetylglucosaminyltransferase: (P. putida) PRPP II: fabF fabD DACSA_RS12025 acetylmuramyl-(pentapeptide) pyruvate N-acetylglutamyl-phosphate (from L-glutamate) murG oxaloacetate pyruvate laurate citramalate N-acetyl-gamma- biosynthetic-type D-glucopyranose lipid II (meso ATP aspartate a malonyl-[acp] 1402 1498 glutamyl-phosphate glu 6-phosphate an (S)-2- phytyl a cytidine a uracil diaminopimelate phosphoribosyltransferase synthase: cimA aminotransferase: acetolactate a 3-oxotetradecanoyl-[acp] a sulfurated [sulfur carrier] SAM a [2-oxoglutarate-dehydrogenase a tRNA precursor chlorophyllide a GGPP reductase: glutamate 5- 6 halocarboxylate 2 diphosphate in 16S rRNA in 16S rRNA GTP containing) regulatory subunit: (R)-citramalate DACSA_RS16220 synthase large sucrose degradation II (sucrose synthase) E2 protein] N -octanoyl-L-lysine bifunctional DACSA_RS06380 kinase: proB beta-ketoacyl-ACP 16S rRNA 16S rRNA DACSA_RS05550 subunit: ilvB γ-L-glutamyl 3-oxoacyl-ACP (cytosine(1402)-N(4) (uracil(1498)-N(3))- geranylgeranyl (R)-2- ornithine L-tryptophan biosynthesis asp lauroyl-CoA synthase III: fabH ATP acetolactate 5-phosphate reductase HAD family chlorophyll )-methyltransferase methyltransferase: diguanylate cyclase: reductase: chlP methylmalate acetyltransferase/ sucrose phosphoribosyltransferase: acetylglutamate synthase small FabG: fabG lipoyl synthase: lipA hydrolase: ribonuclease Z: synthase RsmH: rsmH DACSA_RS10620 DACSA_RS03470 N-acetylglutamate aspartate kinase: glutamate-5- an acetoacetyl-[acp] an N 4 - an N 3 - DACSA_RS17590 hydro-lyase (2- subunit: ilvN 3-oxoacyl-[acyl- lipoyl synthase: lipA DACSA_RS15105 DACSA_RS17310 ChlG: chlG phytyl kinase: argB gln semialdehyde 1402 1498 methylmaleate- synthase: argJ N-acetyl-L-glutamate chorismate DACSA_RS13300 (S)-2-acetolactate carrier-protein] sucrose synthase: [+ 4 isozymes] methylcytidine methyluracil c-di-GMP diphosphate glu gln N-acetyl-L-glutamate dehydrogenase: 1-(5-phospho-β-D-ribosyl)-ATP forming): leuC 5-semialdehyde reductase: fabG DACSA_RS13415 in 16S rRNA in 16S rRNA L-aspartyl- DACSA_RS03295 N-acetylornithine ketol-acid 5'-deoxyadenosine a [2-oxoglutarate dehydrogenase a single-stranded chlorophyll a citraconate anthranilate synthase a (3R)-3- met 6 an unsulfurated [sulfur carrier] an (S)-2- mature tRNA 2 bifunctional carbamoyl- aminotransferase: 4-phosphate reductoisomerase: glutamate-5- CDP-diacylglycerol β-D-fructofuranose UDP-α-D-glucose E2 protein] N -lipoyl-L-lysine a halide anion oligoribonucleotide phosphoribosyl- phosphate bifunctional component I: ilvC hydroxytetradecanoyl-[acp] hydroxycarboxylate Aromatic Compound Biosynthesis β DACSA_RS04130 aspartate- semialdehyde biosynthesis II AMP cyclohydrolase/ -methyl-D- synthase large ornithine DACSA_RS09115 semialdehyde (2R)-2,3-dihydroxy- dehydrogenase: 3-hydroxyacyl- phosphoribosyl-ATP malate hydro- subunit: carB acetyltransferase/ anthranilate synthase DHAP dehydrogenase: 3-methylbutanoate DACSA_RS16820 ACP dehydratase a [glycine-cleavage complex H a [protein]-S- a uridine 34 a [protein]- chorismate biosynthesis I diphosphatase HisIE: lyase (2- N-acetylglutamate component I: trpE NAD(P)H- pimeloyl-CoA phytyl a holo [PedD acyl- roseoflavin pyridoxamine dipicolinate biosynthesis glutamine- FabZ: fabZ α-D-glucopyranose a sulfurated [sulfur carrier] SAM 6 sulfanyl-L-cysteine in tRNA ala chlorophyllide b methylmaleate- synthase: argJ DACSA_RS11675 dihydroxy-acid L-glutamate-5- protein] N -octanoyl-L-lysine 2 diphosphate carrier protein] L-tyrosine 5'-phosphate DACSA_RS10820 hydrolyzing dependent glycerol- 2-deoxy-D-glucose 6- 1-phosphate polysaccharide bifunctional D-erythrose forming): leuC L-aspartate 4- dehydratase: ilvD semialdehyde pyridoxamine carbamoyl- anthranilate PRPP a (2E)-tetradec-2-enoyl-[acp] 3-phosphate phosphate degradation ACP S- biosynthesis riboflavin kinase/ 4-phosphate 1-(5-phospho-β-D-ribosyl)-AMP N-acetyl-L-ornithine semialdehyde alpha-D-glucose tRNA 2- 5'-phosphate 3-deoxy-7- asp (2R,3S)-3-methylmalate phosphate dehydrogenase: chlorophyll malonyltransferase: tyrosine autokinase: FAD synthetase: 3-methyl-2-oxobutanoate 2-deoxy-D- phosphate-specific lipoyl synthase: lipA thiouridine(34) 8-amino-7- oxidase: pdxH phosphoheptulonate aspartate kinase: synthase small homoserine glycine biosynthesis I enoyl-ACP DACSA_RS00500 synthase fabD DACSA_RS15930 DACSA_RS12215 bifunctional anthranilate sn-glycerol glucose 6- phosphoglucomutase: synthase oxononanoate a malonyl- a [protein]- synthase: aroF DACSA_RS13300 subunit: carA dehydrogenase: branched-chain reductase lipoyl synthase: lipA ChlG: chlG roseoflavin 3-deoxy- phosphoribosyl- phosphoribosyltransferase: trpD (S)-1-pyrroline- 3-phosphate phosphatehexitol DACSA_RS12025 MnmA: mnmA synthase: bioF [PedD acyl- L-tyrosine PLP L-aspartyl- L-ornithine DACSA_RS01140 amino acid FabI: fabI 5'-phosphate D-arabino- AMP cyclohydrolase/ 5-carboxylate ser phosphatase D-glucopyranose carrier protein] phosphate 4-phosphate carbamoyl phosphate aminotransferase/ glycerol-3- heptulosonate phosphoribosyl-ATP serine a myristoyl-[acp] 2-deoxy-HxpB: hxpB 6-phosphate a [glycine-cleavage complex H 2-oxobutanoate N-(5-phosphoribosyl)-anthranilate L-homoserine 4-amino-4- pyrroline-5- phosphate 1-O- 5'-deoxyadenosine 34 (8S)-8-amino-7- chlorophyll b 7-phosphate diphosphatase HisIE: met protein] N 6 -[(R)-lipoyl]-L-lysine an unsulfurated [sulfur carrier] a [protein]- a 2-thiouridine coenzyme A 2 aspartate- carboxylate hydroxymethyltransferase: acyltransferase D-glucose glucose-6- oxononanoate 3-dehydroquinate DACSA_RS10820 L-lysine biosynthesis VI deoxychorismate beta-ketoacyl- L-cysteine in tRNA semialdehyde biosynthetic-type phosphoribosylanthranilate homoserine kinase: lyase: reductase: DACSA_RS14555 PlsY: plsY phosphate synthase: gly ACP synthase dehydrogenase: phosphoribosyl-AMP acetolactate isomerase: DACSA_RS14805 DACSA_RS06155 DACSA_RS15155 proC a 1-acyl-sn CDP-diacylglycerol isomerase: DACSA_RS01995 cyclohydrolase: hisI synthase large II: fabF N-acetyl-D-glucosaminyl-N- a 5,6- DACSA_RS11675 ornithine -glycerol 3- biosynthesis I 2-deoxy- DACSA_RS10390 a [pyruvate dehydrogenase E2 a single- sn-glycerol β asp 1-(2-carboxyphenylamino)-1- hν protochlorophyllide a a holo [PedN acyl- 20 a DNA segment 3-dehydroquinate L-aspartate 4- 1-(5-phospho- -D-ribosyl)- subunit: ilvB O-phospho- pro phosphate D-glucono- a sulfurated [sulfur carrier] SAM protein] N 6 -octanoyl-L-lysine acetylmuramoyl-L-alanyl-D-glutamyl- stranded RNA dihydrouracil carbamoyltransferase: aspartate kinase: deoxy-D-ribulose 5-phosphate val a 3-oxohexadecanoyl-[acp] carrier protein] 3-phosphate semialdehyde 5-[(5-phosphoribosylamino) acetolactate L-homoserine 1-acyl-sn-glycerol- DHAP 1,5-lactone F6P 6-carboxy-L-lysyl-D-alanine in tRNA tRNA glycerol-3- type II 3- argF DACSA_RS13300 indole-3-glycerol ACP S- recombinase methylideneamino]imidazole- synthase small threonine 3-phosphate NAD(P)H- dihydrouridine(20/ phosphate dehydroquinate 4-hydroxy- L-aspartyl- phosphate 3-oxoacyl-ACP polyribonucleotide protochlorophyllide malonyltransferase: RecA: recA 4-carboxamide subunit: ilvN synthase: L-alanine acyltransferase: dependent glycerol- 2-deoxy-α-D-ribose 1- 20a) synthase dehydrogenase: dehydratase: aroQ tetrahydrodipicolinate 4-phosphate synthase TrpC: trpC reductase lipoyl synthase: lipA LD-carboxypeptidase: nucleotidyltransferase: reductase: fabD 1-(5-phosphoribosyl)-5- (S)-2-aceto-2- thrC biosynthesis I DACSA_RS06460 3-phosphate phosphate degradation a malonyl[PedN DusA: dusA DACSA_RS09125 a DNA segment synthase: dapA [(5- phosphoribosylamino) FabG: fabG 2-deoxy-D- lipoyl synthase: lipA DACSA_RS15140 DACSA_RS14905 DACSA_RS08540 in reverse hydroxybutanoate (1S,2R)-1-C-(indol-3- [+ 2 isozymes] dehydrogenase: α acyl-carrier 20 DHAP 3-dehydroshikimate (2S,4S)-4- aspartate- [+ 2 isozymes] L-phenylalanine 3-methyl-2- 3-oxoacyl-[acyl- a 1,2-diacyl- gluconate 2-deoxy- -D- a uracil in tRNA methylideneamino]imidazole-4- yl)glycerol 3-phosphate DACSA_RS00500 protein] orientation hydroxy-2,3,4,5- 2-aceto-2-hydroxy- L-citrulline semialdehyde biosynthesis I oxobutanoate carrier-protein] sn-glycerol ribose 1-phosphate shikimate carboxamide isomerase: hisA thr branched-chain sn-glycerol a [pyruvate dehydrogenase N-acetyl-D-glucosaminyl-N- a nucleoside a single- tetrahydrodipicolinate butanoate dehydrogenase: reductase: fabG 3-phosphate 5'-deoxyadenosine chlorophyllide a dehydrogenase: amino acid 3-phosphate met 6 an unsulfurated [sulfur carrier] acetylmuramoyl-L-alanyl-D- D-ala diphosphate stranded RNA phosphoribulosylformimino- isomeroreductase: argininosuccinate DACSA_RS11675 subunit beta: trpB chorismate E2 protein] N -lipoyl-L-lysine DACSA_RS13245 AICAR-phosphate aminotransferase/ a (3R)-3- phosphatidate glycerol-3- 3-dehydro- glutamyl-6-carboxy-L-lysine ilvC synthase: L-aspartate 4- tryptophan synthase L-leucine biosynthesis chorismate 4-amino-4- hydroxyhexadecanoyl-[acp] cytidylyltransferase: phosphate 1-O- 2-deoxy-D- 2-deoxy-D-ribose shikimate dipicolinate (R)-2,3-dihydroxy- DACSA_RS02040 semialdehyde subunit alpha: trpA mutase: aroH deoxychorismate DACSA_RS06070 3-methyl-2- acyltransferase gluconate 5-phosphate imidazole glycerol 3-methylpentanoate ser prephenate lyase: 3-hydroxyacyl- UDP-N-acetyl-α-D-glucosamine undecaprenyl-diphospho-N a DNA containing a ribonucleoside a [protein]- phosphate synthase L-arginino-succinate 4-hydroxy- indole oxobutanoate ACP dehydratase phosphatidate PlsY: plsY -acetylmuramoyl-L-alanyl-γ- isobutanoate an apurinic/ a uracil in DNA a holo [BryP acyl- DNA with lesion shikimate kinase: dihydroxy-acid tetrahydrodipicolinate 2-isopropylmalate DACSA_RS15155 cytidylyltransferase: a 1-acyl-sn carrier protein] 5'-monophosphate L-histidine DACSA_RS03675 subunit HisH: hisH prephenate FabZ: fabZ deoxyribose- D-glutamyl-L-lysyl- D-alanine apyrimidinic site 5'/3'-nucleotidase excinuclease dehydratase: ilvD synthase: dapA synthase: DACSA_RS12500 -glycerol 3- ACP S- imidazole glycerol argininosuccinate tryptophan synthase dehydratase: val phosphate undecaprenyldiphospho- SurE: surE histidine kinase: ABC subunit shikimate 3- (2S,4S)-4- DACSA_RS10365 phosphate uracil-DNA malonyltransferase: phosphate synthase (3S)-3-methyl-2- lyase: argH subunit beta: trpB (2S)-2- pheA a (2E)-hexadec-2-enoyl-[acp] a CDP- aldolase: muramoylpentapeptide beta-N- acetate--CoA DACSA_RS15900 UvrA: uvrA phosphate hydroxy-2,3,4,5- valine--pyruvate 1-acyl-sn-glycerol- endonuclease glycosylase: fabD 5'/3'-nucleotidase subunit HisF: hisF oxopentanoate isopropylmalate diacylglycerol deoC acetylglucosaminyltransferase: ligase: acs a [protein]- [+ 2 isozymes] tetrahydrodipicolinate tryptophan synthase 3-phenyl-2- transaminase: enoyl-ACP 3-phosphate III: nth DACSA_RS04770 a malonyl- SurE: surE DNA without 3-phosphoshikimate 1- branched-chain arg 3-isopropylmalate murG N-phospho- 4-hydroxy- subunit alpha: trpA oxopropanoate DACSA_RS11040 reductase acyltransferase: D-glyceraldehyde [BryP acyl- a ribonucleoside lesion carboxyvinyltransferase: amino acid dehydratase: L-histidine AICAR D-erythro-1-(imidazol-4- tetrahydrodipicolinate aspartate FabI: fabI DACSA_RS06460 acetaldehyde 3-phosphate carrier protein] aroA 3-(4-hydroxyphenyl) aminotransferase/ leuC leuD ditrans,octacis-undecaprenyldiphospho- UDP isobutanoyl-CoA an apyrimidinic uracil 5-enolpyruvoyl- yl)-glycerol 3-phosphate reductase: aminotransferase: ala [+ 2 isozymes] AMP diphosphate a 3'-terminal a 5'-phospho- pyruvate biosynthesis 4-amino-4- DACSA_RS12465 trp DACSA_RS16220 a 1,2-diacyl- bifunctional N-acetyl-(N-acetylglucosaminyl)muramoyl- unsaturated sugar [DNA] site in DNA shikimate 3- imidazoleglycerol- 2-isopropylmaleate a palmitoyl-[acp] γ deoxychorismate sn-glycerol acetaldehyde- L-alanyl- -D-glutamyl-L-lysyl-D-alanine phosphate phosphate glycine biosynthesis II (S)-2,3,4,5- CoA/alcohol tyr lyase: tetrahydrodipicolinate 3-isopropylmalate phe 3-phosphate C1 Compound Utilization and Assimilation chorismate aspartate dehydratase DACSA_RS15155 assimilation cycle III dehydratase: dehydrogenase: a [glycine-cleavage LL-diaminopimelate phosphatidate a [formate C 7,8- γ-glutamyl- synthase: aminotransferase: HisB: hisB leuC leuD adhE a [DNA]-3'- aci-nitroethane a holo [BryU acyl- D-alanyl-D-alanine β-zeacarotene aroC complex H protein] N 6 - aminotransferase: cytidylyltransferase: formaldehyde oxidation acetyltransferase]-glycine a reduced flavodoxin SAM dihydroneopterin hydroxyl isopropylamide 3-(4- DACSA_RS16220 3-(imidazol-4-yl)-2- ile glu L-alanine CO fixation into carrier protein] aminomethyldihydrolipoyl- DACSA_RS04450 L-tyrosine ammonium (2R,3S)-3- palmitate DACSA_RS06070 2 3'-triphosphate D-alanyl-D-alanine ferredoxin: 9,9'-di-cis- hydroxyphenyl) oxopropyl phosphate biosynthesis III II (glutathione-dependent) oxaloacetate (anaplerotic) acetyl-CoA ACP S- chorismate L-lysine biosynthesis I isopropylmalate phosphatidate dipeptidase: DACSA_RS17385 zeta-carotene pyruvate glycine LL-diaminopimelate nitronate malonyltransferase: histidinol-phosphate aminomethyl- 3-isopropylmalate cytidylyltransferase: formaldehyde pyruvate formate exodeoxyribonuclease DACSA_RS16945 ferredoxin: desaturase: cleavage aminotransferase: glutamine CO 6-pyruvoyltetrahydropterin monooxygenase: fabD transaminase: chorismate dehydrogenase: L-cysteine biosynthesis I cys DACSA_RS12500 2 lyase-activating III: xth DACSA_RS01735 zds transferring system gly DACSA_RS11710 synthase: DACSA_RS09405 DACSA_RS10630 a malonyl- γ DACSA_RS02560 chorismate synthetase: leuB cysteine desulfurase: : protein: pflA D-ala N-( -L-glutamyl) γ glycine protein a CDP- [BryU acyl- -carotene L,L- mutase: aroH DACSA_RS17490 DACSA_RS16925 palmitoyl-CoA S-(hydroxymethyl) DACSA_RS08840 -L-alaninol dehydrogenase: GcvH: gcvH (2S)-2-isopropyl- diacylglycerol a 2'- carrier protein] L-histidinol phosphate diaminopimelate [+ 2 isozymes] ser SufS family cysteine glutathione hydrogencarbonate a [formate C acetyltransferase]- (6R)-6-pyruvoyl- a [DNA]-3'- gcvP prephenate 3-oxosuccinate serine O- 5'-deoxyadenosine deoxyribonucleoside acetaldehyde nitrite [+ 2 isozymes] desulfurase: sufS a flavodoxin semiquinone glycin -2-yl radical met 5,6,7,8- triphosphate hydroxyl [+ 2 isozymes]a [glycine-cleavage a [glycine-cleavage diaminopimelate acetyltransferase: S-(hydroxymethyl) phosphoenolpyruvate 5'-monophosphate complex H protein] N 6 complex H protein] N 6 epimerase: prephenate/ ala glutathione tetrahydropterin arogenate gln cysE carboxylase: -dihydrolipoyl-L-lysine -[(R)-lipoyl]-L-lysine DACSA_RS17840 O-acetyl-L-serine dehydrogenase/ dehydrogenase: 4-methyl-2- Biosynthesis DACSA_RS08730 class III alcohol α undecaprenyl-diphospho-N-acetylmuramoyl-L- 527 histidinol meso- DACSA_RS03650 glutamate UDP-N-acetyl- -D-glucosamine lysine within a ribonucleoside a (1->4)- a guanine a [protein]-L- a supercoiled oxopentanoate dehydrogenase: oxaloacetate γ a single α CAIR diaminopimelate 3-(4- synthase large cysteine synthase alanyl- -D-glutamyl-L-lysyl- D-alanyl-D-alanine gcv protein H an octanoyl-[acp] -D-glucan in 16S rRNA proline (ω = 180) duplex DNA branched-chain 3,8-divinyl-chlorophyllide DACSA_RS14245 triphosphate stranded DNA peptidylprolyl histidinol hydroxyphenyl) subunit: gltB A: DACSA_RS00850 3,8-divinyl-chlorophyllide a biosynthesis tetrapyrrole biosynthesis heme a biosynthesis 16S rRNA ATP-dependent 5-(carboxyamino) L-glutamate aminomethyl- diaminopimelate amino acid a biosynthesis I (aerobic, superpathway of biosynthesis from uroporphyrinogen-III undecaprenyldiphospho- isomerase: dehydrogenase: hisD alanine pyruvate cysteine III (aerobic, light independent) I (from glutamate) (guanine(527)-N(7) DNA helicase imidazole biosynthesis III transferring decarboxylase: lysA glu aminotransferase/ light-dependent) S-formylglutathione muramoylpentapeptide beta-N- lipoyl(octanoyl) alpha-glucosidase: DACSA_RS16735 racemization aspartate synthase A: cysK DNA primase: )-methyltransferase RecQ: ribonucleotide histidinal glycine 4-amino-4- uroporphyrinogen-III protoheme acetylglucosaminyltransferase: transferase DACSA_RS09465 uroporphyrinogen-III uroporphyrinogen-III Detoxification 7 RsmG: rsmG [+ 6 isozymes] DACSA_RS16085 mutase: purE aminotransferase: glu protoheme IX S-formylglutathione murG DACSA_RS03855 an N - a [protein]-L- a single 2-oxoglutarate dehydrogenase: lys deoxychorismate cys uroporphyrinogen uroporphyrinogen LipB: lipB 527 ala DACSA_RS16220 glutamate-- uroporphyrinogen : hydrolase: fghA methylguanine ω AIR histidinol glutamate gcvP lyase: decarboxylase: decarboxylase: proline ( = 0) stranded DNA tRNA ligase: decarboxylase: DACSA_RS00805 superoxide a (1->4)- in 16S rRNA dehydrogenase: hisD synthase large [+ 3 isozymes] alanine racemase: tyr DACSA_RS15155 DACSA_RS02210 DACSA_RS02210 arsenate arginine ditrans,octacis-undecaprenyldiphospho-N- UDP a [glycine-cleavage ssDNA/pppN(pN) α D-glucopyranose DACSA_RS07820 DACSA_RS02210 ferroheme o formate radicals degradation -D-glucan subunit: gltB DACSA_RS07275 coproporphyrinogen III coproporphyrinogen III an L-glutamyl- detoxification dependent acetyl-(N-acetyl-β-D-glucosaminyl)muramoyl-L- acyl-carrier protein complex H protein] hybrid 6 n -1 Glu γ N -octanoyl-L-lysine his glu D-ala leu [tRNA ] superoxide II (glutaredoxin) acid resistance alanyl- -D-glutamyl-L-lysyl-D-alanyl-D-alanine oxygen-dependent oxygen-dependent coproporphyrinogen III heme A synthase: DACSA_RS00800 superoxide arsenate Secondary Metabolite Biosynthesis coproporphyrinogen coproporphyrinogen glutamyl-tRNA arg dismutase: arsenate 966 (3Z)-hex- oxidase: hemF oxidase: hemF reductase: oxygen-dependent oxygen-independent biosynthetic dethiobiotin a sulfurated hydrogen selenide D-threo-7,8- a double stranded DNA a guanine 15-cis-phytoene ferroheme i DACSA_RS12685 reductase, SAM O-acetyl-L-serine 3-en-1-ol asp DACSA_RS12260 coproporphyrinogen coproporphyrinogen arginine [sulfur carrier] dihydroneopterin in 16S rRNA methylerythritol protoporphyrinogen IX protoporphyrinogen IX superoxide glutathione/ DNA gyrase 16S rRNA CHAT domain- 15-cis- trans-lycopene biosynthesis myo-inositol preQ biosynthesis (S)-4-amino-5- oxidase: hemF III oxidase: hemN heme A synthase: decarboxylase: subunit A: gyrA containing protein: aspartate phosphate pathway II 0 dismutase, glutaredoxin (guanine(966)-N(2) phytoene biosynthesis Nucleoside and Nucleotide Biosynthesis oxopentanoate speA aminotransferase: II (oxygenic phototrophs protoporphyrinogen protoporphyrinogen DACSA_RS00800 Ni: sodN type: arsC biotin cysteine dihydroneopterin DNA topoisomerase )-methyltransferase DACSA_RS16265 desaturase: D-glyceraldehyde and green sulfur bacteria) glutamate-1- hydrogen agmatine DACSA_RS16220 pyruvate D-glucopyranose oxidase: hemG oxidase: hemG protoporphyrinogen IX protoporphyrinogen IX arsenite synthase synthase aldolase: folB 4 subunit A: 2 RsmD: rsmD [+ 2 isozymes] pds 3-phosphate superpathway of pyrimidine semialdehyde hydroxyferroheme i peroxide an N - (3Z)-hex-3- 9,15,9'-tri-cis 6-phosphate GTP superpathway of superpathway of guanosine 5-aminoimidazole ribonucleotide biosynthesis I BioB: bioB A: cysK DACSA_RS07760 966 oxaloacetate GGPP ribonucleotides de novo biosynthesis adenine and methylguanine ζ GTP adenosine nucleotides nucleotides de novo biosynthesis I protoporphyrin IX protoporphyrin IX 2,1- a negatively en-1-yl acetate - -carotene 1-deoxy-D-xylulose- phytoene synthase: adenosine aminomutase: protoporphyrinogen 6-(hydroxymethyl) supercoiled DNA in 16S rRNA cyclohydrolase de novo biosynthesis I an unsulfurated glycolaldehyde 5-phosphate DACSA_RS07385 gln salvage VI PRPP magnesium magnesium hemL oxidase: hemG biotin 5'-deoxyadenosine met acetate L-selenocysteine -7,8-dihydropterin Ins(3)P I FolE: folE hydrogencarbonate [sulfur carrier] synthase: prephytoene diphosphate IMP chelatase ATPase subunit I: bchI O arsenite GTP IMP 2 DACSA_RS14860 inositol asp adenosine amidophosphoribosyltransferase: ATPase magnesium chelatase 5-aminolevulinate ferroheme a cyclohydrolase DACSA_RS17030 protoporphyrin IX phytoene synthase: monophosphatase: carbamoyl- subunit I: bchI subunit H: DACSA_RS16935 7,8- adenosine kinase: an (S-diacyl-sn- a 3,5,7,9,11,13,15- 1939 1-deoxy-D-xylulose I FolE: folE 5-phospho-β- porphobilinogen : an L-1- 3-aci- S-(2-hydroxyacyl) a uracil DACSA_RS07385 DACSA_RS17320 dihydroneopterin phosphate DACSA_RS07905 gly magnesium glyceryl)-L-cysteinyl- hepta-oxo- a [protein] Ser/Thr propanoate 15-cis-phytoene 5-phosphate adenylosuccinate D-ribosylamine Mg-protoporphyrin synthase: hemB DACSA_RS17365 phosphatidylethanolamine nitropropanoate glutathione in 23S rRNA 3'-triphosphate synthase chelatase subunit H: [apolipoprotein] hexadecanoyl-[PKS-acp] serine/threonine 23S rRNA 15-cis- 1-deoxy-D-xylulose- 15-cis-phytoene myo-inositol synthase: AMP aldo/keto large DACSA_RS16935 magnesium protoporphyrin porphobilinogen ferrochelatase: chlorophyll cycle protein kinase: (uracil(1939)-C(5)) acetate kinase: phytoene 5-phosphate DACSA_RS13375 phosphoribosylamine- nitronate reductase: subunit: carB XMP IX methyltransferase: DACSA_RS09475 hydroxyacylglutathione DACSA_RS15655 -methyltransferase DACSA_RS11230 desaturase: reductoisomerase: 15-cis-phytoene -glycine ligase: purD Mg-protoporphyrin Amine and Polyamine Degradation apolipoprotein N- monooxygenase: DACSA_RS02475 glutamine- DACSA_RS17830 hydroxymethylbilane hydrolase: gloB [+ 3 isozymes] RlmD: rlmD pds 6-carboxy-5,6,7,8- protoheme chlorophyllide a acyltransferase: lnt [+ 4 isozymes] 1939 propanoyl DACSA_RS11560 desaturase: pds adenylo-succinate glutamine- synthase: hemC DACSA_RS10630 9-hydroxy-3,5,7,11,13,15- a [protein] (L-serine/L- a 5-methyluracil all-trans tetrahydropterin hydrolyzing magnesium magnesium-protoporphyrin phosphate hydrolyzing GMP GAR N-acetylglucosamine hexaoxohexadecanoyl- threonine) phosphate in 23S rRNA phytofluene MEP 15,9'-di-cis-phytofluene carbamoyl- adenylosuccinate protoporphyrin IX IX 13-monomethyl ester allantoin degradation urea degradation II an N-acyl-(S-diacyl- 7-carboxy-7- synthase: guaA preuroporphyrinogen chlorophyll degradation I a 2-acyl-1-lyso- [unspecified a 2-hydroxy [PKS-acp] fluoroacetate and phosphate lyase: methyltransferase: magnesium-protoporphyrin to ureidoglycolate sn-glyceryl)-L- glutathione deazaguanine phosphoribosylglycinamide synthase ChlG: chlG N-acetyl-D- phosphatidylethanolamine 3-oxopropanoate nitrite degradation carboxylate 2-C-methyl-D- 15-cis-phytoene fluorothreonine biosynthesis synthase DACSA_RS10815 DACSA_RS17830 IX monomethyl ester uroporphyrinogen- I (urea producing) cysteinyl-[lipoprotein] synthase QueE: small GMP formyltransferase: magnesium- glucosamine urea products] erythritol 4-phosphate desaturase: pds (oxidative) cyclase: acsF III synthase: chlorophyll a 7 1 -hydroxychlorophyllide a (S)-(+)-allantoin DACSA_RS09665 subunit: carA DACSA_RS05160 protoporphyrin IX 6-phosphateN-acetylglucosamine- urease: ureC cytidylyltransferase: magnesium-protoporphyrin DACSA_RS15260 allantoinase ζ 7-carboxy-7- AMP 1 6-phosphate DACSA_RS06755 α DACSA_RS15700 9,15,9'-tri-cis- -carotene guanylate kinase: FGAR 13-monomethyl ester IX monomethyl ester 7 -hydroxychlorophyll pyridin-1-ium-3-carboxylate-5- D-xylulose (R)-S- -L-fucosyl-(1->3)- an insertion sequence a [protein]- a [protein]- SAM-dependent deazaguanine magnesium- deacetylase: nagA PuuE: puuE ureA a [LarE]-L-cysteine β GGPP π 4-(cytidine 5'- carbamoyl DACSA_RS12710 (oxidative) cyclase: acsF uroporphyrinogen-III a reductase: D-glucosamine thiocarboxylate mononucleotide 5-phosphate lactoylglutathione -D-glucopyranosyl- element IS30 N -phospho- N-phospho- chlorinase/fluorinase: 7-cyano-7- asp phosphoribosylformylglycinamidine protoporphyrin allantoate urease: ureC L-histidine L-histidine diphospho)-2-C- phosphate adenylate kinase: 1 DACSA_RS12450 6-phosphate diphosphoundecaprenolcolanic acid transposase: DACSA_RS12945 deazaguanine synthase: purS purQ IX monomethyl 13 -hydroxy-magnesium- DACSA_RS08085 phosphohistidine phosphohistidine methyl-D-erythritol DACSA_RS18035 7 1 -hydroxychlorophyll a 7 1 -dihydroxychlorophyllide a biosynthesis DACSA_RS01420 phytoene synthase: GDP ester (oxidative) protoporphyrin IX 13-monomethyl ester DACSA_RS08090 ATP-dependent phosphatase phosphatase 4-(cytidine 5'- 5'-deoxy-5'-fluoroadenosine synthase phosphoribosylformylglycinamidine phosphoketolase: hydroxyacylglutathione acetyltransferase [+ 8 isozymes] DACSA_RS07385 9,9'-di-cis-ζ-carotene aspartate cyclase: acsF magnesium-protoporphyrin ammonium sacrificial sulfur SixA: sixA SixA: sixA diphospho)- QueC: queC synthase subunit PurL: purL DACSA_RS03305 hydrolase: gloB α WcaF: wcaF an insertion carbamoyltransferase ADP IX monomethyl ester α-D-glucosamine transferase LarE: larE [2/3-O-acetyl- -L-fucosyl]- a [protein]- a [protein]- 2-C-methyl-D- magnesium- β sequence IS30 with 15-cis-phytoene 9,9'-di-cis- preQ catalytic subunit: FGAM (oxidative) cyclase: acsF biosynthesis 6-phosphate (S)-ureidoglycolate (1->3)- -D-glucopyranosyl- L-histidine L-histidine erythritol kinase: zeta-carotene 0 DACSA_RS06125 nucleoside- inosine-5'-phosphate biosynthesis I protoporphyrin diphosphoundecaprenol integrated transposon DACSA_RS07355 diphosphate kinase: magnesium-protoporphyrin pyridin-1-ium-3,5- D-glyceraldehyde desaturase: zds 5-fluoro-5-deoxy-D- phosphoribosylformylglycinamidine IX monomethyl chlorophyll b chlorophyllide b a [LarE]-dehydroalanine acetyl phosphate 3-phosphate (R)-lactate glutathione 2-phospho-4-(cytidine DACSA_RS03410 ester (oxidative) IX monomethyl ester uroporphyrinogen-III bisthiocarboxylate mononucleotide ribose 1-phosphate AIR cyclo-ligase: DACSA_RS05465 5'-diphospho)-2-C- 7,9,9'-cis-neurosporene N-carbamoyl- cyclase: acsF (oxidative) cyclase: acsF uroporphyrinogen-III C- dGDP F6P methyl-D-erythritol L-aspartate 13 1 -hydroxy- 13 1 -oxo-magnesium-protoporphyrin methyltransferase: cobA 2-C-methyl-D- 9,9'-di-cis- 5-(carboxyamino)imidazole AIR chlorophyll pyridin-1-ium-3,5- a nucleoside a long-linear an N-terminal L- a [protein]- dADP magnesium- IX 13-monomethyl ester uroporphyrinogen-III C- D-fructofuranose α-D-glucopyranose τ zeta-carotene phytyl diphosphate dihydroorotase: GTP nucleoside- ribonucleotide synthase: synthase ChlG: chlG a [LarE]-L-cysteine diphosphate- α-D-glucan alanyl-[S18 protein a cytosine in DNA an acyl phosphate N -phospho- gly erythritol 2,4- 5-fluoro-5-deoxy-D- protoporphyrin IX methyltransferase: cobA dicarboxylate mononucleotide desaturase: zds biosynthesis DACSA_RS04705 diphosphate kinase: DACSA_RS12495 magnesium-protoporphyrin glucose of 30S ribosome] DNA cytosine L-histidine cyclodiphosphate ribulose 1-phosphate nucleoside- 13-monomethyl ester precorrin-1 ribosomal protein dihydroorotase: DACSA_RS03410 superpathway of pyrimidine IX monomethyl ester methyltransferase: acylphosphatase: phosphohistidine glycine synthase: diphosphate kinase: N5-CAIR magnesium- 4-alpha- S18-alanine N- prolycopene GGPP pyrC nucleobases salvage (oxidative) cyclase: acsF uroporphyrinogen-III C- Amino Acid Degradation ATP-dependent dcm DACSA_RS05560 phosphatase oxidase DACSA_RS12365 DACSA_RS03410 protoporphyrin sucrose synthase: glucanotransferase: acetyltransferase: geranylgeranyl dGTP magnesium-protoporphyrin methyltransferase: cobA sacrificial sulfur [+ 7 isozymes] SixA: sixA ThiO: thiO (S)-dihydroorotate 5-(carboxyamino)imidazole uracil IX monomethyl biosynthesis DACSA_RS13415 malQ an N-terminal N-acetyl-rimI 2-C-methyl-D-erythritol- carotene reductase: chlP IX monomethyl ester uroporphyrinogen-III C- L-glutamate transferase LarE: larE a 5-methylcytosine a carboxylate a [protein]- glyoxylate dATP ribonucleotide mutase: purE bifunctional pyr operon ester (oxidative) L-citrulline degradation L-alanyl-[S18 protein 2,4-cyclodiphosphate isomerase: crtH fluoroacetaldehyde dihydrogeranylgeranyl (oxidative) cyclase: acsF methyltransferase: cobA degradation VI L-glutamate in DNA L-histidine diphosphate quinone-dependent asp transcriptional regulator/uracil cyclase: acsF protoheme degradation II a nucleoside sucrose a short 1,4- of 30S ribosome] (E)-4-hydroxy- CAIR (to pyruvate) pyridin-1-ium-3-carboxylate-5- α all-trans-lycopene dihydroorotate phosphoribosyltransferase magnesium- 3,8-divinyl protochlorophyllide a precorrin-2 heme b biosynthesis a [LarE]-dehydroalanine diphosphate -D-glucan 3-methylbut- fluoroacetaldehyde geranylgeranyl L-citrulline thiocarboxylate mononucleotide dehydrogenase: PyrR: pyrR protoporphyrin I (aerobic) glu glu 2-enyl- dehydrogenase: reductase: chlP ferredoxin:protochlorophyllide ornithine DACSA_RS08250 phosphoribosylaminoimidazolesuccinocarboxamide uracil IX monomethyl (Z,Z)- aspartate diphosphate DACSA_RS12670 reductase (ATP-dependent) carbamoyltransferase: a [protein]- tetrahydrogeranylgeranyl PRPP synthase: DACSA_RS02865 phosphoribosyltransferase: ester (oxidative) uroporphyrinogen-III biliverdin-IX α aminotransferase: 3-methyl-2- 5,10-methylene- adenine 1518 / a guanosine 18 synthase: ispG 4-fluorothreonine orotate subunit N: DACSA_RS06015 argF protochlorophyllide a citrate an mRNA DACSA_RS05115 1519 L-tyrosine D-ala (E)-4-hydroxy-3- diphosphate CMP phosphorylation cyclase: acsF uroporphyrinogen phycocyanobilin:ferredoxin carbamoyl phosphate DACSA_RS16220 oxobutanoate tetrahydromethanopterin adenine in 16S rRNA in tRNA fluoroacetate UMP 13 1 -oxo-magnesium- ferredoxin:protochlorophyllide sirohydrochlorin decarboxylase: oxidoreductase: asp ferredoxin:protochlorophyllide 16S rRNA tRNA bifunctional phosphate methylbut-2-en- IPP orotate SAICAR mRNA protein-tyrosine- glycine geranylgeranyl protoporphyrin IX reductase (ATP-dependent) DACSA_RS02210 DACSA_RS06955 (2S, 3S)-3- reductase (ATP-dependent) (adenine(1518)-N(6)/ (guanosine(18)-2'-O) aconitate hydratase 1-yl diphosphate phosphoribosyltransferase: CMP UMP kinase: sirohydrochlorin carbamoyl-phosphate 3-methyl-2-oxobutanoate interferase PemK: phosphatase: oxidase reductase: chlP 13-monomethyl ester subunit B: DACSA_RS09180 coproporphyrinogen III methylaspartate aspartate subunit N: DACSA_RS06015 adenine(1519)-N(6))- -methyltransferase 2/2-methylisocitrate DACSA_RS02070 bifunctional pantoate--beta- adenylosuccinate lyase: DACSA_RS04750 chelatase: (2R,3Z)- synthase large hydroxymethyltransferase: DACSA_RS15445 DACSA_RS03120 ThiO: thiO ammonia-lyase: ferredoxin:protochlorophyllide dimethyltransferase TrmH: trmH dehydratase: acnB phytyl alanine ligase/(d)CMP DACSA_RS10815 UDP magnesium- chlorophyllide a DACSA_RS16690 phycocyanobilin subunit: carB panB a 2'-O- a [protein]- 2 oxygen-dependent RsmA: rsmA an mRNA fragment protoporphyrin DACSA_RS09075 reductase (ATP-dependent) 6 1518 18 D-threo-isocitrate pyruvate diphosphate orotidine 5'- kinase: DACSA_RS11835 sirohydrochlorin coproporphyrinogen glutamine-hydrolyzing N -dimethyladenine methylguanosine L-tyrosine CDP AICAR nucleoside-diphosphate IX monomethyl subunit B: DACSA_RS09180 6 1519 in tRNA phosphate chelatase: oxidase: hemF carbamoyl-phosphate fumarate /N -dimethyladenine DMAPP kinase: DACSA_RS03410 ester (oxidative) 2-dehydropantoate THMPT chlorophyllide a in 16S rRNA nucleoside-diphosphate bifunctional DACSA_RS14435 mesaconate synthase small orotidine-5'- UTP cyclase: acsF protoporphyrinogen IX (2R,3E)- kinase: DACSA_RS03410 phosphoribosylaminoimidazolecarboxamide phycocyanobilin subunit: carA phosphate magnesium- siroheme decarboxylase: CTP formyltransferase/IMP cyclohydrolase: purH CTP synthase: protoporphyrin protoporphyrinogen carbamate 5-amino-4- DNA combined with a [2-oxoglutarate 4-hydroxy-3- pyrF DACSA_RS17350 PRPP maltohexaose uroporphyrinogen-I a glycogen FAICAR IX monomethyl oxidase: hemG imidazolecarboxyamide exogenous DNA to form dehydrogenase E2 protein] octaprenylbenzoate Ins(1)P CTP 6 glycogen UMP ester (oxidative) (S)-citramalate L-methionine degradation a recombinational junction N -dihydrolipoyl-L-lysine uroporphyrinogen UbiD family bifunctional protoporphyrin IX Holliday junction dihydrolipoyl inositol debranching cyclase: acsF I (to L-homocysteine) decarboxylase: decarboxylase: UMP kinase: phosphoribosylaminoimidazolecarboxamide adenine resolvase RuvX: ruvX alpha-glucosidase: dehydrogenase: monophosphatase: protein 3,8-divinyl ferrochelatase: citramalate CO phosphoribosyltransferase: crossover junction DACSA_RS09465 lpdA DACSA_RS02210 DACSA_RS17220 DACSA_RS17320 DACSA_RS04750 formyltransferase/IMP cyclohydrolase: purH 2 GlgX: glgX protochlorophyllide a DACSA_RS17365 synthase: met DACSA_RS05445 endodeoxyribonuclease a [2-oxoglutarate UDP coproporphyrinogen I 2-octaprenylphenol myo-inositol a maltodextrin pyrimidine deoxyribonucleotide phosphorylation protochlorophyllide ferrochelatase: cimA methionine resolution of recombinationalRuvC: ruvC dehydrogenase E2 IMP protein] N 6 -lipoyl-L-lysine nucleoside- reductase: DACSA_RS09475 adenosyltransferase: junction formation D-glucopyranose maltopentaose diphosphate kinase: dTMP dCMP DACSA_RS08540 DACSA_RS10315 AICAR acetate pyruvate of two intact strands DACSA_RS03410 dTMP kinase: bifunctional pantoate--beta- protoheme SAM gln DACSA_RS04665 alanine ligase/(d)CMP chlorophyllide a 2 UTP dTDP kinase: DACSA_RS11835 a double nucleoside-diphosphate dCDP acetyl-CoA malonyl-CoA NADPH H + D-glucopyranose a maltodextrin maltoheptaose ethylphosphate oxaloacetate Ins(2)P acetamide CTP synthase: stranded DNA kinase: DACSA_RS03410 DACSA_RS17350 nucleoside-diphosphate L-arginine degradation III alkaline phosphatase: DNA/RNA inositol acetamidase/ kinase: DACSA_RS03410 (arginine decarboxylase/ SAH citrate synthase: dTTP 4-alpha- alpha-glucosidase: DACSA_RS20895 nuclease monophosphatase: formamidase: agmatinase pathway) fatty-acid synthase: DACSA_RS12505 CTP dCTP glucanotransferase: DACSA_RS09465 alkaline phosphatase: SfsA: sfsA DACSA_RS17320 DACSA_RS04445 adenosylhomocysteinase: DACSA_RS14940 malQ DACSA_RS08495 1,2-dihydroxypropane- arg a 5'-phosphooligonucleotide myo-inositol acetate DACSA_RS07400 ethanol 1,2,3-tricarboxylate biosynthetic a long-chain D-glucopyranose maltohexaose arginine L-homocysteine a maltodextrin maltose decarboxylase: fatty acyl-CoA speA agmatine a soluble 967 L-glutamine UDP-N-acetyl-α-D-muramoyl- D-glucopyranose a cytosine (S)-2-aceto-2- (2R,3S)-3- a D-hexose D-alanyl-D-alanine heteroglycan maltopentaose formamide agmatinase: degradation I L-alanyl-γ-D-glutamyl-L-lysine in 16S rRNA hydroxybutanoate isopropylmalate 16S rRNA ketol-acid 3-isopropylmalate acetamidase/ speB L-glutamine glucokinase: gln 4-alpha- (cytosine(967)-C(5)) reductoisomerase: dehydrogenase: DACSA_RS10535 formamidase: degradation II UDP-N-acetylmuramoyl- alpha-glucosidase: -methyltransferase: putrescine Asp-tRNA(Asn) tripeptide--D-alanyl-D- glucanotransferase: DACSA_RS09465 ilvC leuB DACSA_RS04445 malQ DACSA_RS14975 (R)-2,3-dihydroxy- 4-methyl-2- D-hexose 6- /Glu-tRNA(Gln) alanine ligase: murF a 5-methylcytosine 967 gln phosphate formate amidotransferase in 16S rRNA 3-methylpentanoate oxopentanoate glutamate subunit GatC: gatC a plant soluble synthase large UDP-N-acetyl-α-D-muramoyl-L-alanyl- maltose D-glucopyranose maltotetraose [+ 9 isozymes] γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine heteroglycan L-asparagine subunit: gltB glu degradation I glu UDP-4-amino-D-fucose a supercoiled geranylgeranyl D-glucopyranose maltopentaose D-glucopyranose maltotetraose maltotriose pyruvate precorrin-6B asn UDP-4-amino-4, 6- duplex DNA chlorophyll a phosphoenolpyruvate precorrin-6Y C5,15- ATP-dependent asparaginase: dideoxy-N-acetyl- geranylgeranyl 4-alpha- 4-alpha- synthase: methyltransferase helicase: DACSA_RS09360 L-aspartate alpha-glucosidase: beta-L-altrosamine reductase: chlP glucanotransferase: glucanotransferase: DACSA_RS15875 subunit CbiT: cbiT DACSA_RS00740 asp degradation I DACSA_RS09465 transaminase: pseC malQ malQ UDP-4-dehydro-6- phosphoenol precorrin-8x a single chlorophyll a α asp deoxy- -D-glucose pyruvate stranded DNA aspartate maltose maltotetraose maltose maltotriose D-glucopyranose maltose aminotransferase: L-alanine DACSA_RS16220 oxaloacetate an [amino-group carrier protein]- degradation IV 3-phospho- a uridine 55 7,8-dihydro- adenosyl-cob(III) D-glucopyranose maltohexaose maltotriose a glucan γ L-cysteate C-terminal- -(L-glutamate 5- D-glycerate in tRNA 8-oxoguanine yrinate a,c-diamide ala semialdehyde-2-yl)-L-glutamateN-acetyl-gamma- phosphoglycerate tRNA aspartate 8-oxoguanine cobyric acid alanine 4-alpha- 4-alpha- glutamyl-phosphate dehydrogenase: pseudouridine(55) aminotransferase: deaminase: synthase dehydrogenase: ald glucanotransferase: glucanotransferase: reductase: DACSA_RS09415 synthase TruB: truB DACSA_RS16220 DACSA_RS02105 CobQ: cobQ malQ malQ DACSA_RS06380 a pseudouridine 55 pyruvate an [amino-group carrier protein]- 3-phosphooxypyruvate 3-sulfopyruvate urate adenosylcobyrate C-terminal-γ-(5-phospho- in tRNA L-glutamyl)-L-glutamate Alcohol Degradation maltopentaose maltose a glucan D-glucopyranose

glycerol and glycerophosphodiester degradation 2,5-diamino-6-(5- 2-amino-6-[1-hydroxyethyl]- UDP-4-amino-4-deoxy- (2R,3S)-3- D-mannitol ethanol uroporphyrinogen-III β an adenine in DNA ferroheme o phospho-D-ribitylamino) 7-methyl-7,8-dihydropterin -L-arabinopyranose isopropylmalate 1-phosphate degradation II UDP-4-amino-4, 6- a glycerophosphodiester pyrimidin-4(3H)-one 2-amino-4-hydroxy-6- uroporphyrinogen-III C- DNA adenine 3-isopropylmalate hexitol bifunctional dideoxy-N-acetyl- heme A synthase: ethanol hydroxymethyldihydropteridine methyltransferase: cobA methylase: dehydratase: phosphatase glycerol diaminohydroxyphosphoribosylaminopyrimidine beta-L-altrosamine DACSA_RS00800 bifunctional diphosphokinase: folK uroporphyrinogen-III C- DACSA_RS00215 leuC leuD HxpB: hxpB glycerophosphoryl deaminase/5-amino-6-(5-phosphoribosylamino) transaminase: pseC acetaldehyde- [1-(2-amino-7-methyl-4-oxo- methyltransferase: cobA β an N 6 -methyladenine (2S)-2- diester uracil reductase RibD: ribD UDP- -L-threo- ferroheme a D-mannitol CoA/alcohol 5-amino-6-(5-phospho- 7,8-dihydro-3H-pteridin- precorrin-2 in DNA isopropylmalate phosphodiesterase: pentapyranos-4-ulose dehydrogenase: D-ribitylamino)uracil 6-yl)]ethyl diphosphate DACSA_RS02715 glycerol adhE glycerophosphoryl acetaldehyde 34 D-sorbitol diester glycerol a 5-carboxymethylaminomethyluridine a glucosylated glycogenin 3-phenyl-2- 2'-deoxycytidine wound RNA maltose phosphoenol in tRNA Leu oxopropanoate pyruvate 6-phosphate phosphodiesterase: kinase acetaldehyde 1,4-alpha-glucan-branching nucleoside deaminase: tRNA (uridine(34)/cytosine(34)/5- DNA/RNA helicase: pyruvate kinase: hexitol DACSA_RS05430 GlpK: glpK dehydrogenase: protein: DACSA_RS03145 4-hydroxyphenylpyruvate DACSA_RS15905 alpha-glucosidase: carboxymethylaminomethyluridine(34) DACSA_RS16980 DACSA_RS11410 phosphatase adhE dioxygenase: hppD nucleoside deaminase: DACSA_RS09465 -2'-O)- methyltransferase TrmL: trmL 1,4-alpha-glucan branching [+ 3 isozymes] [+ 2 isozymes] HxpB: hxpB sn-glycerol DACSA_RS17895 acetate a 5-carboxymethylaminomethyl- protein GlgB: glgB (2-hydroxyphenyl) 3-phosphate 2'-deoxyuridine an unwound RNA D-glucopyranose pyruvate D-sorbitol 2'-O-methyluridine 34 in tRNA Leu a glycogen acetate glycerol-3- acetate--CoA phosphate ligase: acs dehydrogenase: 4a-hydroxy-N 10 - UDP-2-acetamido-4-amino- cytidine sucrose 6 F a cytidine 34 in tRNA α an α-limit dextrin GDP-β-L-fucose acetyl-CoA formyltetrahydrofolate 2,4,6-trideoxy- -D-galactose -phosphate DACSA_RS09125 UDP-4-amino-4, 6- nucleoside deaminase: tRNA (uridine(34)/cytosine(34)/5- 4a-hydroxytetrahydrobiopterin 4-alpha- GDP-L-fucose sucrose-phosphate dideoxy-N-acetyl- DACSA_RS15905 DHAP carboxymethylaminomethyluridine(34) dehydratase: glucanotransferase: synthase: phosphatase: beta-L-altrosamine nucleoside deaminase: -2'-O)- methyltransferase TrmL: trmL DACSA_RS03920 malQ DACSA_RS09220 DACSA_RS03375 transaminase: pseC a α-limit dextrin DACSA_RS17895 GDP-4-dehydro- ethanol a 2'-O-methylcytidine 34 an N 10 -formyl- UDP-2-acetamido-2,6- uridine α sucrose degradation I in tRNA 7,8-dihydrofolate dideoxy-α-D-xylo-hex-4-ulose with short branches -D-rhamnose

ethanol bifunctional acetaldehyde- CoA/alcohol dehydrogenase: adhE acetaldehyde

bifunctional acetaldehyde- CoA/alcohol dehydrogenase: adhE

acetyl-CoA

a reduced a reduced plastocyanin an amino folate plastocyanin acid an oxidized a branched- a branched- phosphonate sodium a 7,8- an alkylphosphonate an oxidized an inorganic an inorganic an amino phosphonate glutamate plastocyanin an amino chain chain phosphonate dihydrobiopterin an (aminoalkyl)phosphonate plastocyanin anion anion acid a carbohydrate a carbohydrate phosphite acid amino acid amino acid a lipopolysaccharide a lipopolysaccharide chromate a polysaccharide predicted ABC predicted ABC cytochrome RS06300 RS17195 RS02000 RS11070 RS00790 RS17080 RS11805 RS17485 transporter RS08270 RS02250 RS12165 RS08585 RS10835 RS07350 RS10825 RS11070 transporter of RS11065 RS07860 RS15525 c oxidase of an phosphonate amino acid a branched- a branched- sodium an alkylphosphonate an inorganic an inorganic an amino a carbohydrate a carbohydrate phosphonate glutamate a 7,8- chain chain phosphonate bicarbonate an (aminoalkyl)phosphonate O anion anion acid an amino a lipopolysaccharide a lipopolysaccharide phosphite chromate a polysaccharide dihydrobiopterin 2 O amino acid amino acid phosphonate H O 2 an amino acid 2 H O folate 2 acid This diagram was automatically generated by SRI International Pathway Tools version 25.0, authors S. Paley and P.D. Karp.