Model Name: "Jamshidi2007

SBML Model Report

Model name: “Jamshidi2007 - Genome-scale metabolic network of Mycobacterium tuberculosis (iNJ661)”

2LATEX July 28, 2015

1 General Overview

This is a document in SBML Level 3 Version 1 format. Table1 shows an overview of the quantities of all components of this model.

Table 1: Number of components in this model, which are described in the following sections. Element Quantity Element Quantity compartment types 0 compartments 2 species types 0 species 826 events 0 constraints 0 reactions 1025 function deﬁnitions 0 global parameters 19 unit deﬁnitions 1 rules 0 initial assignments 0

Model Notes Jamshidi2007 - Genome-scale metabolic networkof Mycobacterium tuberculosis (iNJ661) This model is described in the article:Investigating the metabolic capabilities of Mycobac- terium tuberculosis H37Rv using the in silico strain iNJ661 and proposing alternative drug targets.Jamshidi N, Palsson B.BMC Syst Biol 2007; 1: 26 Abstract:

Produced by SBML2LATEX 1 BACKGROUND: Mycobacterium tuberculosis continues to be a major pathogen in the third world, killing almost 2 million people a year by the most recent estimates. Even in industrialized countries, the emergence of multi-drug resistant (MDR) strains of tuberculosis hails the need to develop additional medications for treatment. Many of the drugs used for treatment of tuberculosis target metabolic enzymes. Genome-scale models can be used for analysis, discovery, and as hypothesis generating tools, which will hopefully assist the rational drug development process. These models need to be able to assimilate data from large datasets and analyze them. RESULTS: We completed a bottom up reconstruction of the metabolic network of Mycobac- terium tuberculosis H37Rv. This functional in silico bacterium, iNJ661, contains 661 genes and 939 reactions and can produce many of the complex compounds characteristic to tuberculosis, such as mycolic acids and mycocerosates. We grew this bacterium in silico on various media, analyzed the model in the context of multiple high-throughput data sets, and finally we analyzed the network in an ’unbiased’ manner by calculating the Hard Coupled Reaction (HCR) sets, groups of reactions that are forced to operate in unison due to mass conservation and con- nectivity constraints. CONCLUSION: Although we observed growth rates comparable to experimental observations (doubling times ranging from about 12 to 24 hours) in different media, comparisons of gene essentiality with experimental data were less encouraging (generally about 55%). The reasons for the often conflicting results were multi-fold, including gene expression variability under different conditions and lack of complete biological knowledge. Some of the inconsistencies between in vitro and in silico or in vivo and in silico results highlight specific loci that are worth further experimental investigations. Finally, by considering the HCR sets in the context of known drug targets for tuberculosis treatment we proposed new alternative, but equivalent drug targets. This model is hosted on BioModels Database and identified by: MODEL1507180001. To cite BioModels Database, please use: BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. To the extent possible under law, all copyright and related or neighbouring rights to this en- coded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more information.

2 Unit Deﬁnitions

This is an overview of six unit definitions of which five are predefined by SBML and not men- tioned in the model.

2.1 Unit mmol per gDW per hr −1 Deﬁnition mmol · g−1 · (3600 s)

2.2 Unit substance Notes Mole is the predeﬁned SBML unit for substance.

Deﬁnition mol

2 Produced by SBML2LATEX 2.3 Unit volume Notes Litre is the predeﬁned SBML unit for volume.

Deﬁnition l

2.4 Unit area Notes Square metre is the predeﬁned SBML unit for area since SBML Level 2 Version 1.

Deﬁnition m2

2.5 Unit length Notes Metre is the predeﬁned SBML unit for length since SBML Level 2 Version 1.

Deﬁnition m

2.6 Unit time Notes Second is the predeﬁned SBML unit for time.

Deﬁnition s

3 Compartments

This model contains two compartments.

Table 2: Properties of all compartments. Id Name SBO Spatial Size Unit Constant Outside Dimensions c Cytosol 3 1 litre e Extraorganism 3 1 litre 2 2 3.1 Compartment c This is a three dimensional compartment with a constant size given in litre.

Name Cytosol

3.2 Compartment e This is a three dimensional compartment with a constant size given in litre.

Name Extraorganism

Produced by SBML2LATEX 3 4 4 Species

This model contains 826 species. Section7 provides further details and the derived rates of change of each species.

Table 3: Properties of each species. Id Name Compartment Derived Unit Constant Boundary Condi- tion M 10fthf c 10-Formyltetrahydrofolate c mol · l−1 – – M 12dgr160 c 1,2-Diacyl-sn-glycerol (dihexadecanoyl, c mol · l−1 – – rdcdby Produced n-C16:0) 2 2 − 2 2 M 13dpg c 3-Phospho-D-glyceroyl phosphate c mol · l 1 – – M 1hdecg3p c 1-hexadecanoyl-sn-glycerol 3-phosphate c mol · l−1 – – − 2 2 M 1msg3p c 1-Acyl-sn-glycerol 3-phosphate (branched c mol · l 1 – – 2 2 SBML C19:0) − 2 2 M 1pyr5c c 1-Pyrroline-5-carboxylate c mol · l 1 – –

2 −1 L A M 23dhba c (2,3-Dihydroxybenzoyl)adenylate c mol · l – – T

E −1 2 2

X M 23dhdp c 2,3-Dihydrodipicolinate c mol · l – – − 2 2 M 23dhmb c (R)-2,3-Dihydroxy-3-methylbutanoate c mol · l 1 – – − 2 2 M 23dhmp c (R)-2,3-Dihydroxy-3-methylpentanoate c mol · l 1 – – − 2 2 M 25aics c (S)-2-[5-Amino-1-(5-phospho- c mol · l 1 – – D-ribosyl)imidazole-4- 2 2 carboxamido]succinate 2 2 M 25dhpp c 2,5-Diamino-6-hydroxy-4-(5’- c mol · l−1 – – phosphoribosylamino)-pyrimidine − 2 2 M 25drapp c 2,5-Diamino-6-(ribosylamino)-4-(3H)- c mol · l 1 – – pyrimidinone 5’-phosphate − 2 2 M 26dap DASH LL c LL-2,6-Diaminoheptanedioate c mol · l 1 – – M 26dap DASH M c meso-2,6-Diaminoheptanedioate c mol · l−1 – – 2 2 2 2 Id Name Compartment Derived Unit Constant Boundary Condi- tion M 2agpe160 c 2-Acyl-sn-glycero-3- c mol · l−1 – – phosphoethanolamine (n-C16:0) − 2 2 M 2agpe180 c 2-Acyl-sn-glycero-3- c mol · l 1 – – phosphoethanolamine (n-C18:0) − 2 2 M 2ahbut c (S)-2-Aceto-2-hydroxybutanoate c mol · l 1 – – M 2ahhmd c 2-Amino-4-hydroxy-6-hydroxymethyl- c mol · l−1 – – 7,8-dihydropteridine diphosphate 2 2 −1 2 2 rdcdby Produced M 2ahhmp c 2-Amino-4-hydroxy-6-hydroxymethyl- c mol · l – – 7,8-dihydropteridine − 2 2 M 2c25dho c 2-Carboxy-2,5-dihydro-5-oxofuran-2- c mol · l 1 – – acetate − 2 2 M 2cpr5p c 1-(2-Carboxyphenylamino)-1-deoxy-D- c mol · l 1 – – SBML ribulose 5-phosphate −1 2 2

2 M 2dda7p c 2-Dehydro-3-deoxy-D-arabino-heptonate c mol · l – – L A T

E 7-phosphate

X − 2 2 M 2dglcn c 2-Deoxy-D-gluconate c mol · l 1 – – M 2dhp c 2-Dehydropantoate c mol · l−1 – – − 2 2 M 2dmmq6 c 2-Demethylmenaquinone 6 c mol · l 1 – – − 2 2 M 2dmmq8 c 2-Demethylmenaquinone 8 c mol · l 1 – – − 2 2 M 2dmmql8 c 2-Demethylmenaquinol 8 c mol · l 1 – – − 2 2 M 2dr1p c 2-Deoxy-D-ribose 1-phosphate c mol · l 1 – – − 2 2 M 2dr5p c 2-Deoxy-D-ribose 5-phosphate c mol · l 1 – – − 2 2 M 2ippm c 2-Isopropylmaleate c mol · l 1 – – − 2 2 M 2mahmp c 2-Methyl-4-amino-5- c mol · l 1 – – hydroxymethylpyrimidine diphosphate 2 2 − 2 2 M 2me4p c 2-C-methyl-D-erythritol 4-phosphate c mol · l 1 – – 5 2 2 6 Id Name Compartment Derived Unit Constant Boundary Condi- tion M 2mecdp c 2-C-methyl-D-erythritol 2,4- c mol · l−1 – – cyclodiphosphate − 2 2 M 2mop c 2-Methyl-3-oxopropanoate c mol · l 1 – – M 2obut c 2-Oxobutanoate c mol · l−1 – – − 2 2 M 2p4c2me c 2-phospho-4-(cytidine 5’-diphospho)-2- c mol · l 1 – – C-methyl-D-erythritol 2 2 − 2 2 M 2pg c D-Glycerate 2-phosphate c mol · l 1 – – −1 rdcdby Produced M 2pglyc c 2-Phosphoglycolate c mol · l – – − 2 2 M 2shchc c 2-Succinyl-6-hydroxy-2,4- c mol · l 1 – – cyclohexadiene-1-carboxylate 2 2 − 2 2 M 34hpp c 3-(4-Hydroxyphenyl)pyruvate c mol · l 1 – – M 35cgmp c 3’,5’-Cyclic GMP c mol · l−1 – – SBML − 2 2 M 3c2hmp c 3-Carboxy-2-hydroxy-4- c mol · l 1 – – 2 2

2 methylpentanoate L A − T · 1 2 2 E M 3c3hmp c 3-Carboxy-3-hydroxy-4- c mol l – – X methylpentanoate − 2 2 M 3c4mop c 3-Carboxy-4-methyl-2-oxopentanoate c mol · l 1 – – M 3ddgc c 3-Dehydro-2-deoxy-D-gluconate c mol · l−1 – – − 2 2 M 3dhq c 3-Dehydroquinate c mol · l 1 – – − 2 2 M 3dhsk c 3-Dehydroshikimate c mol · l 1 – – − 2 2 M 3ig3p c C’-(3-Indolyl)-glycerol 3-phosphate c mol · l 1 – – − 2 2 M 3mob c 3-Methyl-2-oxobutanoate c mol · l 1 – – − 2 2 M 3mop c (S)-3-Methyl-2-oxopentanoate c mol · l 1 – – − 2 2 M 3pg c 3-Phospho-D-glycerate c mol · l 1 – – − 2 2 M 3php c 3-Phosphohydroxypyruvate c mol · l 1 – – − 2 2 M 3psme c 5-O-(1-Carboxyvinyl)-3- c mol · l 1 – – 2 2 phosphoshikimate 2 2 Id Name Compartment Derived Unit Constant Boundary Condi- tion M 4abut c 4-Aminobutanoate c mol · l−1 – – M 4abz c 4-Aminobenzoate c mol · l−1 – – − 2 2 M 4adcho c 4-amino-4-deoxychorismate c mol · l 1 – – − 2 2 M 4ahmmp c 4-Amino-5-hydroxymethyl-2- c mol · l 1 – – methylpyrimidine 2 2 − 2 2 M 4ampm c 4-Amino-2-methyl-5- c mol · l 1 – – phosphomethylpyrimidine −1 2 2 rdcdby Produced M 4c2me c 4-(cytidine 5’-diphospho)-2-C-methyl-D- c mol · l – – erythritol − 2 2 M 4h2opntn c 4-Hydroxy-2-oxopentanoate c mol · l 1 – – M 4hba c 4-Hydroxy-benzyl alcohol c mol · l−1 – – − 2 2 M 4hbzACP c 4-hydroxybenzoyl ACP c mol · l 1 – – SBML − 2 2 M 4hbz c 4-Hydroxybenzoate c mol · l 1 – – −1 2 2

2 M 4hthr c 4-Hydroxy-L-threonine c mol · l – – L A − T · 1 2 2 E M 4mhetz c 4-Methyl-5-(2-hydroxyethyl)-thiazole c mol l – –

X − 2 2 M 4mop c 4-Methyl-2-oxopentanoate c mol · l 1 – – − 2 2 M 4mpetz c 4-Methyl-5-(2-phosphoethyl)-thiazole c mol · l 1 – – − 2 2 M 4pasp c 4-Phospho-L-aspartate c mol · l 1 – – − 2 2 M 4per c 4-Phospho-D-erythronate c mol · l 1 – – − 2 2 M 4ppan c D-4’-Phosphopantothenate c mol · l 1 – – − 2 2 M 4ppcys c N-((R)-4-Phosphopantothenoyl)-L- c mol · l 1 – – cysteine 2 2 − 2 2 M 4r5au c 4-(1-D-Ribitylamino)-5-aminouracil c mol · l 1 – – M 5aizc c 5-amino-1-(5-phospho-D- c mol · l−1 – – ribosyl)imidazole-4-carboxylate 2 2 − 2 2 M 5aop c 5-Amino-4-oxopentanoate c mol · l 1 – – 7 2 2 8 Id Name Compartment Derived Unit Constant Boundary Condi- tion M 5aprbu c 5-Amino-6-(5’- c mol · l−1 – – phosphoribitylamino)uracil − 2 2 M 5apru c 5-Amino-6-(5’- c mol · l 1 – – phosphoribosylamino)uracil − 2 2 M 5caiz c 5-phosphoribosyl-5- c mol · l 1 – – carboxyaminoimidazole − 2 2 M 5dglcn c 5-Dehydro-D-gluconate c mol · l 1 – – −1 rdcdby Produced M 5fthf c 5-Formyltetrahydrofolate c mol · l – – − 2 2 M 5mta c 5-Methylthioadenosine c mol · l 1 – – − 2 2 M 5mthf c 5-Methyltetrahydrofolate c mol · l 1 – – − 2 2 M 5mtr c 5-Methylthio-D-ribose c mol · l 1 – – − 2 2 M 5odhf2a c 5-Oxo-4,5-dihydrofuran-2-acetate c mol · l 1 – – SBML − 2 2 M 5oxpro c 5-Oxoproline c mol · l 1 – – −1 2 2

2 M 5prdmbz c N1-(5-Phospho-alpha-D-ribosyl)-5,6- c mol · l – – L A

T 2 2

E dimethylbenzimidazole

X − 2 2 M 6hmhpt c 6-hydroxymethyl dihydropterin c mol · l 1 – – M 6hmhptpp c 6-hydroxymethyl-dihydropterin py- c mol · l−1 – – rophosphate 2 2 − 2 2 M 6pgc c 6-Phospho-D-gluconate c mol · l 1 – – M 6pgl c 6-phospho-D-glucono-1,5-lactone c mol · l−1 – – − 2 2 M 8aonn c 8-Amino-7-oxononanoate c mol · l 1 – – − 2 2 M ACP c acyl carrier protein c mol · l 1 – – − 2 2 M Ac1PIM1 c acyl phosphatidylinositol mannoside (tu- c mol · l 1 – – berculosis) 2 2 − 2 2 M Ac1PIM2 c acyl phosphatidylinositol mannoside di- c mol · l 1 – – mannose (tuberculosis) 2 2 Id Name Compartment Derived Unit Constant Boundary Condi- tion M Ac1PIM3 c acyl phosphatidylinositol mannoside tri- c mol · l−1 – – mannose (tuberculosis) − 2 2 M Ac1PIM4 c acyl phosphatidylinositol mannoside tetra- c mol · l 1 – – mannose (tuberculosis) − 2 2 M Ac2PIM2 c di-acyl phosphatidylinositol mannoside c mol · l 1 – – di-mannose (tuberculosis) − 2 2 M PIM1 c phosphatidylinositol mannoside (tubercu- c mol · l 1 – –

rdcdby Produced losis) − 2 2 M PIM2 c phosphatidylinositol mannoside di- c mol · l 1 – – mannose (tuberculosis) − 2 2 M PIM3 c phosphatidylinositol mannoside tri- c mol · l 1 – – mannose (tuberculosis) SBML − 2 2 M PIM4 c phosphatidylinositol mannoside tetra- c mol · l 1 – –

2 mannose (tuberculosis) L A − T · 1 2 2 E M PIM5 c phosphatidylinositol mannoside penta- c mol l – – X mannose (tuberculosis) − 2 2 M PIM6 c phosphatidylinositol mannoside hexa- c mol · l 1 – – mannose (tuberculosis) − 2 2 M aacoa c Acetoacetyl-CoA c mol · l 1 – – M ac c Acetate c mol · l−1 – – − 2 2 M acac c Acetoacetate c mol · l 1 – – − 2 2 M acald c Acetaldehyde c mol · l 1 – – − 2 2 M accoa c Acetyl-CoA c mol · l 1 – – − 2 2 M acg5p c N-Acetyl-L-glutamyl 5-phosphate c mol · l 1 – – − 2 2 M acg5sa c N-Acetyl-L-glutamate 5-semialdehyde c mol · l 1 – – − 2 2 M acgam1p c N-Acetyl-D-glucosamine 1-phosphate c mol · l 1 – – −1 2 2 9 M acgam6p c N-Acetyl-D-glucosamine 6-phosphate c mol · l – – 2 2 2 2 10 Id Name Compartment Derived Unit Constant Boundary Condi- tion M acgam c N-Acetyl-D-glucosamine c mol · l−1 – – M acglu c N-Acetyl-L-glutamate c mol · l−1 – – − 2 2 M achms c O-Acetyl-L-homoserine c mol · l 1 – – − 2 2 M acorn c N2-Acetyl-L-ornithine c mol · l 1 – – − 2 2 M acser c O-Acetyl-L-serine c mol · l 1 – – − 2 2 M actp c Acetyl phosphate c mol · l 1 – – − 2 2 M acysbmn c acetyl-cystine-bimane c mol · l 1 – – −1 2 2 rdcdby Produced M acysbmn e acetyl-cystine-bimane e mol · l – – − 2 2 M ad c acetamide c mol · l 1 – – − 2 2 M adcobdam c Adenosyl cobyrinate diamide c mol · l 1 – – − 2 2 M adcobhex c adenosyl-cobyric acid c mol · l 1 – – − 2 2 M ade c Adenine c mol · l 1 – – SBML − 2 2 M adfdOX c Oxidized adrenal ferredoxin c mol · l 1 – – −1 2 2

2 M adfdRD c Reduced adrenal ferredoxin c mol · l – – L A − T · 1 2 2 E M adhlam c S-Acetyldihydrolipoamide c mol l – –

X − 2 2 M adn c Adenosine c mol · l 1 – – − 2 2 M adocbi c Adenosyl cobinamide c mol · l 1 – – − 2 2 M adocbip c Adenosyl cobinamide phosphate c mol · l 1 – – − 2 2 M adocbl c Adenosylcobalamin c mol · l 1 – – − 2 2 M adp c ADP c mol · l 1 – – − 2 2 M adpglc c ADPglucose c mol · l 1 – – − 2 2 M agalfragund c arabinofuranose-galactofuranosyl(30)- c mol · l 1 – – rhamanosyl-N-acetylglucosamyl- 2 2 undecaprenyl diphosphate (M tb) 2 2 M agdpcbi c Adenosine-GDP-cobinamide c mol · l−1 – – M agm c Agmatine c mol · l−1 – – − 2 2 M ahcys c S-Adenosyl-L-homocysteine c mol · l 1 – – 2 2 2 2 Id Name Compartment Derived Unit Constant Boundary Condi- tion M ahdt c 2-Amino-4-hydroxy-6-(erythro-1,2,3- c mol · l−1 – – trihydroxypropyl)dihydropteridine triphosphate 2 2 M aicar c 5-Amino-1-(5-Phospho-D- c mol · l−1 – – ribosyl)imidazole-4-carboxamide − 2 2 M air c 5-amino-1-(5-phospho-D- c mol · l 1 – – ribosyl)imidazole −1 2 2 rdcdby Produced M akg c 2-Oxoglutarate c mol · l – – M ala DASH B c beta-Alanine c mol · l−1 – – − 2 2 M ala DASH B e beta-Alanine e mol · l 1 – – − 2 2 M ala DASH D c D-Alanine c mol · l 1 – – − 2 2 M ala DASH D e D-Alanine e mol · l 1 – – SBML − 2 2 M ala DASH L c L-Alanine c mol · l 1 – – −1 2 2

2 M ala DASH L e L-Alanine e mol · l – – L A − T · 1 2 2 E M alaala c D-Alanyl-D-alanine c mol l – –

X − 2 2 M alac DASH S c (S)-2-Acetolactate c mol · l 1 – – − 2 2 M alatrna c L-Alanyl-tRNA(Ala) c mol · l 1 – – − 2 2 M alpam c S-aminomethyldihydrolipoamide c mol · l 1 – – − 2 2 M alpro c S-Aminomethyldihydrolipoylprotein c mol · l 1 – – − 2 2 M amet c S-Adenosyl-L-methionine c mol · l 1 – – − 2 2 M ametam c S-Adenosylmethioninamine c mol · l 1 – – − 2 2 M amob c S-Adenosyl-4-methylthio-2-oxobutanoate c mol · l 1 – – − 2 2 M amp c AMP c mol · l 1 – – − 2 2 M anth c Anthranilate c mol · l 1 – – − 2 2 M apoACP c apoprotein [acyl carrier protein] c mol · l 1 – – − 2 2 M appl c 1-Aminopropan-2-ol c mol · l 1 – –

11 − 2 2 M applp c D-1-Aminopropan-2-ol O-phosphate c mol · l 1 – – 2 2 2 2 12 Id Name Compartment Derived Unit Constant Boundary Condi- tion M aps c Adenosine 5’-phosphosulfate c mol · l−1 – – M arab DASH D c D-Arabinose c mol · l−1 – – − 2 2 M arab DASH D e D-Arabinose e mol · l 1 – – − 2 2 M arab DASH L c L-Arabinose c mol · l 1 – – − 2 2 M arab DASH L e L-Arabinose e mol · l 1 – – − 2 2 M arabinan c arabinan complex (Mtb) c mol · l 1 – – − 2 2 M- arabinan-arabinofuranose- c mol · l 1 – – 2 2 rdcdby Produced arabinanagalfragund-galactofuranosyl(30)-rhamanosyl-N- c acetylglucosamyl-undecaprenyl diphos- 2 2 phate (M tb) M arachACP c eicosanoyl-ACP (n-C20:0) c mol · l−1 – – M arach c Arachidic acid c mol · l−1 – – SBML − 2 2 M arachcoa c arachidyl coenzyme A c mol · l 1 – – −1 2 2

2 M arg DASH L c L-Arginine c mol · l – – L A − T · 1 2 2 E M arg DASH L e L-Arginine e mol l – –

X − 2 2 M argsuc c N(omega)-(L-Arginino)succinate c mol · l 1 – – − 2 2 M arpp c 5-phosphoarabinose pyrophosphate c mol · l 1 – – − 2 2 M asn DASH L c L-Asparagine c mol · l 1 – – − 2 2 M asn DASH L e L-Asparagine e mol · l 1 – – − 2 2 M asp DASH L c L-Aspartate c mol · l 1 – – − 2 2 M asp DASH L e L-Aspartate e mol · l 1 – – − 2 2 M aspsa c L-Aspartate 4-semialdehyde c mol · l 1 – – − 2 2 M atp c ATP c mol · l 1 – – − 2 2 M atp e ATP e mol · l 1 – – − 2 2 M betald c Betaine aldehyde c mol · l 1 – – − 2 2 M bhb c (R)-3-Hydroxybutanoate c mol · l 1 – – − 2 2 M bmn c bimane c mol · l 1 – – 2 2 2 2 Id Name Compartment Derived Unit Constant Boundary Condi- tion M bmn e bimane e mol · l−1 – – M bmnmsh c bimane conjugated mycothiol (mtb) c mol · l−1 – – − 2 2 M btamp c Biotinyl-5’-AMP c mol · l 1 – – − 2 2 M btn c Biotin c mol · l 1 – – − 2 2 M ca2 c Calcium c mol · l 1 – – − 2 2 M ca2 e Calcium e mol · l 1 – – − 2 2 M camp c cAMP c mol · l 1 – – −1 2 2 rdcdby Produced M cbasp c N-Carbamoyl-L-aspartate c mol · l – – − 2 2 M cbi c Cobinamide c mol · l 1 – – − 2 2 M cbl1 c Cob(I)alamin c mol · l 1 – – − 2 2 M cbp c Carbamoyl phosphate c mol · l 1 – – − 2 2 M cdp c CDP c mol · l 1 – – SBML − 2 2 M cdpc16c19g c cdp diacylglycerol (C16:0, C19:0) c mol · l 1 – – −1 2 2

2 M cdpc19c19g c cdp diacylglycerol (C19:0, C19:0) c mol · l – – L A − T · 1 2 2 E M cdpdhdecg c CDP-1,2-dihexadecanoylglycerol c mol l – –

X − 2 2 M cdpdodecg c CDP-1,2-dioctadecanoylglycerol c mol · l 1 – – − 2 2 M cgly c Cys-Gly c mol · l 1 – – − 2 2 M chexccoa c carboxy hexacosanoyl-CoA c mol · l 1 – – − 2 2 M chol c Choline c mol · l 1 – – − 2 2 M chol e Choline e mol · l 1 – – − 2 2 M chor c chorismate c mol · l 1 – – − 2 2 M cigam c cys-1D-myo-inositol 2-deoxy-D- c mol · l 1 – – glucopyranoside 2 2 − 2 2 M cit c Citrate c mol · l 1 – – M cit e Citrate e mol · l−1 – – − 2 2 M citr DASH L c L-Citrulline c mol · l 1 – –

13 − 2 2 M cl c Chloride c mol · l 1 – – 2 2 2 2 14 Id Name Compartment Derived Unit Constant Boundary Condi- tion M cl e Chloride e mol · l−1 – – M clpn160190 c cardiolipin (dihexadecanoyl, dimethyl- c mol · l−1 – – stearoyl) 2 2 − 2 2 M cmcbtt c carboxymycobactin T (R=8 carbon, ﬁnal c mol · l 1 – – carbon is carboxyl group) − 2 2 M cmp c CMP c mol · l 1 – – M co1dam c Cob(I)yrinate a,c diamide c mol · l−1 – – −1 2 2 rdcdby Produced M co2 c CO2 c mol · l – – − 2 2 M co2 e CO2 e mol · l 1 – – − 2 2 M co2dam c Cob(II)yrinate a,c diamide c mol · l 1 – – − 2 2 M co c Carbon monoxide c mol · l 1 – – − 2 2 M co e Carbon monoxide e mol · l 1 – – SBML − 2 2 M coa c Coenzyme A c mol · l 1 – – −1 2 2

2 M coa e Coenzyme A e mol · l – – L A − T · 1 2 2 E M cobalt2 c Co2+ c mol l – –

X − 2 2 M cobalt2 e Co2+ e mol · l 1 – – − 2 2 M cobya c Cobyrinate c mol · l 1 – – − 2 2 M codhpre6 c cobalt-dihydro-precorrin 6 c mol · l 1 – – − 2 2 M copre2 c cobalt-precorrin 2 c mol · l 1 – – − 2 2 M copre3 c cobalt-precorrin 3 c mol · l 1 – – − 2 2 M copre4 c cobalt-precorrin 4 c mol · l 1 – – − 2 2 M copre5 c cobalt-precorrin 5 c mol · l 1 – – − 2 2 M copre6 c cobalt-precorrin 6 c mol · l 1 – – − 2 2 M copre8 c cobalt-precorrin 8 c mol · l 1 – – − 2 2 M cpppg1 c Coproporphyrinogen I c mol · l 1 – – − 2 2 M cpppg3 c Coproporphyrinogen III c mol · l 1 – – − 2 2 M crn c L-Carnitine c mol · l 1 – – 2 2 2 2 Id Name Compartment Derived Unit Constant Boundary Condi- tion M crn e L-Carnitine e mol · l−1 – – M ctp c CTP c mol · l−1 – – − 2 2 M cu2 c Cu2+ c mol · l 1 – – − 2 2 M cu2 e Cu2+ e mol · l 1 – – − 2 2 M cyan c Hydrogen cyanide c mol · l 1 – – − 2 2 M cys DASH L c L-Cysteine c mol · l 1 – – − 2 2 M cyst DASH L c L-Cystathionine c mol · l 1 – – −1 2 2 rdcdby Produced M cytd c Cytidine c mol · l – – − 2 2 M cytd e Cytidine e mol · l 1 – – − 2 2 M dad DASH 2 c Deoxyadenosine c mol · l 1 – – − 2 2 M dadp c dADP c mol · l 1 – – − 2 2 M damp c dAMP c mol · l 1 – – SBML − 2 2 M dann c 7,8-Diaminononanoate c mol · l 1 – – −1 2 2

2 M datp c dATP c mol · l – – L A − T · 1 2 2 E M db4p c 3,4-dihydroxy-2-butanone 4-phosphate c mol l – –

X − 2 2 M dca c Decanoate (n-C10:0) c mol · l 1 – – − 2 2 M dcamp c N6-(1,2-Dicarboxyethyl)-AMP c mol · l 1 – – − 2 2 M dcdp c dCDP c mol · l 1 – – − 2 2 M dcmp c dCMP c mol · l 1 – – − 2 2 M dctp c dCTP c mol · l 1 – – − 2 2 M dcyt c Deoxycytidine c mol · l 1 – – − 2 2 M ddca c Dodecanoate (n-C12:0) c mol · l 1 – – − 2 2 M decd tb c (E,E,E,E,E,E,E,Z,Z) decaprenyl phos- c mol · l 1 – – phate 2 2 − 2 2 M decda tb c decaprenylphosphoryl-beta-D- c mol · l 1 – – arabinofuranose

15 2 2 16 Id Name Compartment Derived Unit Constant Boundary Condi- tion M decdman1p tb c (E,E,E,E,E,E,E,Z,Z) decaprenyl mannose c mol · l−1 – – phosphate − 2 2 M decdp c all trans Decaprenyl diphosphate c mol · l 1 – – M decdp tb c (E,E,E,E,E,E,E,Z,Z) Decaprenyl diphos- c mol · l−1 – – phate 2 2 − 2 2 M decdpa tb c decaprenylphosphoryl-beta-D-5- c mol · l 1 – – phosphoarabinofuranose −1 2 2 rdcdby Produced M decdpr tb c decaprenylphosphoryl-beta-D-5- c mol · l – – phosphoribose − 2 2 M decdr tb c decaprenylphosphoryl-beta-D-5-ribose c mol · l 1 – – M dgdp c dGDP c mol · l−1 – – − 2 2 M dgmp c dGMP c mol · l 1 – – SBML − 2 2 M dgsn c Deoxyguanosine c mol · l 1 – – −1 2 2

2 M dgtp c dGTP c mol · l – – L A − T · 1 2 2 E M dhap c Dihydroxyacetone phosphate c mol l – –

X − 2 2 M dhf c 7,8-Dihydrofolate c mol · l 1 – – − 2 2 M dhlam c Dihydrolipoamide c mol · l 1 – – − 2 2 M dhlpro c Dihydrolipolprotein c mol · l 1 – – − 2 2 M dhna c 1,4-Dihydroxy-2-naphthoate c mol · l 1 – – − 2 2 M dhnpt c Dihydroneopterin c mol · l 1 – – − 2 2 M dhor DASH S c (S)-Dihydroorotate c mol · l 1 – – − 2 2 M dhpmp c Dihydroneopterin monophosphate c mol · l 1 – – − 2 2 M dhpt c Dihydropteroate c mol · l 1 – – − 2 2 M din c Deoxyinosine c mol · l 1 – – − 2 2 M dmarach c di-methyl arachic acid c mol · l 1 – – − 2 2 M dmbhn c di-methyl behenic acid c mol · l 1 – – − 2 2 M dmbzid c 5,6-Dimethylbenzimidazole c mol · l 1 – – 2 2 2 2 Id Name Compartment Derived Unit Constant Boundary Condi- tion M dmlgnc c dimethyl lignoceric acid c mol · l−1 – – M dmlz c 6,7-Dimethyl-8-(1-D-ribityl)lumazine c mol · l−1 – – − 2 2 M dmpp c Dimethylallyl diphosphate c mol · l 1 – – − 2 2 M dnad c Deamino-NAD+ c mol · l 1 – – − 2 2 M dpcoa c Dephospho-CoA c mol · l 1 – – − 2 2 M dscl c dihydrosirohydrochlorin c mol · l 1 – – − 2 2 M dtbt c Dethiobiotin c mol · l 1 – – −1 2 2 rdcdby Produced M dtdp4d6dg c dTDP-4-dehydro-6-deoxy-D-glucose c mol · l – – − 2 2 M dtdp4d6dm c dTDP-4-dehydro-6-deoxy-L-mannose c mol · l 1 – – − 2 2 M dtdp c dTDP c mol · l 1 – – − 2 2 M dtdpglu c dTDPglucose c mol · l 1 – – − 2 2 M dtdprmn c dTDP-L-rhamnose c mol · l 1 – – SBML − 2 2 M dtmp c dTMP c mol · l 1 – – −1 2 2

2 M dttOX c Oxidized dithiothreitol c mol · l – – L A − T · 1 2 2 E M dtt c Dithiothreitol c mol l – –

X − 2 2 M dttp c dTTP c mol · l 1 – – − 2 2 M dudp c dUDP c mol · l 1 – – − 2 2 M dump c dUMP c mol · l 1 – – − 2 2 M duri c Deoxyuridine c mol · l 1 – – − 2 2 M dutp c dUTP c mol · l 1 – – − 2 2 M dxyl5p c 1-deoxy-D-xylulose 5-phosphate c mol · l 1 – – − 2 2 M dxyl c 1-deoxy-D-xylulose c mol · l 1 – – − 2 2 M e4p c D-Erythrose 4-phosphate c mol · l 1 – – − 2 2 M eig3p c D-erythro-1-(Imidazol-4-yl)glycerol c mol · l 1 – – 3-phosphate 2 2 − 2 2 M enter c Enterochelin c mol · l 1 – – 17 M etha c Ethanolamine c mol · l−1 – – 2 2 2 2 18 Id Name Compartment Derived Unit Constant Boundary Condi- tion M etha e Ethanolamine e mol · l−1 – – M f6p c D-Fructose 6-phosphate c mol · l−1 – – − 2 2 M fad c Flavin adenine dinucleotide oxidized c mol · l 1 – – − 2 2 M fadh2 c Flavin adenine dinucleotide reduced c mol · l 1 – – − 2 2 M fald c Formaldehyde c mol · l 1 – – − 2 2 M fc1p c L-Fuculose 1-phosphate c mol · l 1 – – − 2 2 M fcmcbtt c iron(III) chelated carboxymycobactin T c mol · l 1 – – 2 2 rdcdby Produced (R=8 carbon, ﬁnal carbon is carboxyl group) 2 2 M fdox c ferredoxin (oxidized) 2[4Fe-4S] c mol · l−1 – – M fdp c D-Fructose 1,6-bisphosphate c mol · l−1 – – − 2 2 M fdred c ferredoxin (reduced) 2[4Fe-4S] c mol · l 1 – – SBML − 2 2 M fdxox c Oxidized ferredoxin c mol · l 1 – – −1 2 2

2 M fdxrd c Reduced ferredoxin c mol · l – – L A − T · 1 2 2 E M fe2 c Fe2+ c mol l – –

X − 2 2 M fe2 e Fe2+ e mol · l 1 – – − 2 2 M fe3 c Fe3+ c mol · l 1 – – − 2 2 M fe3 e Fe3+ e mol · l 1 – – − 2 2 M fgam c N2-Formyl-N1-(5-phospho-D- c mol · l 1 – – ribosyl)glycinamide 2 2 − 2 2 M ficytc c Ferricytochrome c c mol · l 1 – – M fmcbtt c Iron(II) mycobactin T c mol · l−1 – – − 2 2 M fmettrna c N-Formylmethionyl-tRNA c mol · l 1 – – − 2 2 M fmn c FMN c mol · l 1 – – − 2 2 M focytc c Ferrocytochrome c c mol · l 1 – – − 2 2 M fol c Folate c mol · l 1 – – − 2 2 M for c Formate c mol · l 1 – – 2 2 2 2 Id Name Compartment Derived Unit Constant Boundary Condi- tion M forcoa c Formyl-CoA c mol · l−1 – – M fpram c 2-(Formamido)-N1-(5-phospho-D- c mol · l−1 – – ribosyl)acetamidine 2 2 − 2 2 M fprica c 5-Formamido-1-(5-phospho-D- c mol · l 1 – – ribosyl)imidazole-4-carboxamide − 2 2 M frdp c Farnesyl diphosphate c mol · l 1 – – M frrppdima c fucose rhamnose rhamnose phenol phthio- c mol · l−1 – – 2 2 rdcdby Produced cerol dimycocerosate (Mtb) − 2 2 M fum c Fumarate c mol · l 1 – – M fum e Fumarate e mol · l−1 – – − 2 2 M g1p c D-Glucose 1-phosphate c mol · l 1 – – − 2 2 M g3p c Glyceraldehyde 3-phosphate c mol · l 1 – – SBML − 2 2 M g3pe c sn-Glycero-3-phosphoethanolamine c mol · l 1 – – −1 2 2

2 M g6p c D-Glucose 6-phosphate c mol · l – – L A − T · 1 2 2 E M gal1p c alpha-D-Galactose 1-phosphate c mol l – –

X − 2 2 M gal c D-Galactose c mol · l 1 – – − 2 2 M gal e D-Galactose e mol · l 1 – – − 2 2 M galfragund c galactofuranosyl(30)-rhamanosyl-N- c mol · l 1 – – acetylglucosamyl-undecaprenyl diphos- 2 2 phate (M tb) 2 2 M gam1p c D-Glucosamine 1-phosphate c mol · l−1 – – M gam6p c D-Glucosamine 6-phosphate c mol · l−1 – – − 2 2 M gar c N1-(5-Phospho-D-ribosyl)glycinamide c mol · l 1 – – − 2 2 M gcald c Glycolaldehyde c mol · l 1 – – − 2 2 M gdp c GDP c mol · l 1 – – − 2 2 M gdpddman c GDP-4-dehydro-6-deoxy-D-mannose c mol · l 1 – –

19 − 2 2 M gdpfuc c GDP-L-fucose c mol · l 1 – – 2 2 2 2 20 Id Name Compartment Derived Unit Constant Boundary Condi- tion M gdpmann c GDP-D-mannose c mol · l−1 – – M gdptp c Guanosine 3’-diphosphate 5’-triphosphate c mol · l−1 – – − 2 2 M glc DASH D c D-Glucose c mol · l 1 – – − 2 2 M glc DASH D e D-Glucose e mol · l 1 – – − 2 2 M glcn c D-Gluconate c mol · l 1 – – − 2 2 M gln DASH L c L-Glutamine c mol · l 1 – – − 2 2 M glu1sa c L-Glutamate 1-semialdehyde c mol · l 1 – – −1 2 2 rdcdby Produced M glu5p c L-Glutamate 5-phosphate c mol · l – – − 2 2 M glu5sa c L-Glutamate 5-semialdehyde c mol · l 1 – – − 2 2 M glu DASH D c D-Glutamate c mol · l 1 – – − 2 2 M glu DASH L c L-Glutamate c mol · l 1 – – − 2 2 M glu DASH L e L-Glutamate e mol · l 1 – – SBML − 2 2 M gluala c 5-L-Glutamyl-L-alanine c mol · l 1 – – −1 2 2

2 M glucys c gamma-L-Glutamyl-L-cysteine c mol · l – – L A − T · 1 2 2 E M glutrna c L-Glutamyl-tRNA(Glu) c mol l – –

X − 2 2 M glx c Glyoxylate c mol · l 1 – – − 2 2 M gly c Glycine c mol · l 1 – – − 2 2 M gly e Glycine e mol · l 1 – – − 2 2 M glyb c Glycine betaine c mol · l 1 – – − 2 2 M glyb e Glycine betaine e mol · l 1 – – − 2 2 M glyc3p c Glycerol 3-phosphate c mol · l 1 – – − 2 2 M glyc3p e Glycerol 3-phosphate e mol · l 1 – – − 2 2 M glyc DASH R c (R)-Glycerate c mol · l 1 – – − 2 2 M glyc c Glycerol c mol · l 1 – – − 2 2 M glyc e Glycerol e mol · l 1 – – − 2 2 M glyclt c Glycolate c mol · l 1 – – − 2 2 M glycogen c glycogen c mol · l 1 – – 2 2 2 2 Id Name Compartment Derived Unit Constant Boundary Condi- tion M gmp c GMP c mol · l−1 – – M grdp c Geranyl diphosphate c mol · l−1 – – − 2 2 M gsn c Guanosine c mol · l 1 – – − 2 2 M gthox c Oxidized glutathione c mol · l 1 – – − 2 2 M gthrd c Reduced glutathione c mol · l 1 – – − 2 2 M gthrd e Reduced glutathione e mol · l 1 – – − 2 2 M gtp c GTP c mol · l 1 – – −1 2 2 rdcdby Produced M gua c Guanine c mol · l – – − 2 2 M h2 c H2 c mol · l 1 – – − 2 2 M h2 e H2 e mol · l 1 – – − 2 2 M h2co3 c carbonic acid c mol · l 1 – – − 2 2 M h2co3 e carbonic acid e mol · l 1 – – SBML − 2 2 M h2mb4p c 1-hydroxy-2-methyl-2-(E)-butenyl 4- c mol · l 1 – – 2 2

2 diphosphate L A − T · 1 2 2 E M h2o2 c Hydrogen peroxide c mol l – – X M h2o c H2O c mol · l−1 – – − 2 2 M h2o e H2O e mol · l 1 – – − 2 2 M h2s c Hydrogen sulﬁde c mol · l 1 – – − 2 2 M h2s e Hydrogen sulﬁde e mol · l 1 – – − 2 2 M h c H+ c mol · l 1 – – − 2 2 M h e H+ e mol · l 1 – – − 2 2 M harab DASH D c hexa arabinofuranoside c mol · l 1 – – − 2 2 M hco3 c Bicarbonate c mol · l 1 – – − 2 2 M hcys DASH L c L-Homocysteine c mol · l 1 – – − 2 2 M hdca c Hexadecanoate (n-C16:0) c mol · l 1 – – − 2 2 M hdca e Hexadecanoate (n-C16:0) e mol · l 1 – –

21 − 2 2 M hdcea c Hexadecenoate (n-C16:1) c mol · l 1 – – 2 2 2 2 22 Id Name Compartment Derived Unit Constant Boundary Condi- tion M hdcoa c Hexadecenoyl-CoA (n-C16:1CoA) c mol · l−1 – – M hexc c hexacosanoate (n-C26:0) c mol · l−1 – – − 2 2 M hexccoa c Hexacosanoyl-CoA (n-C26:0CoA) c mol · l 1 – – − 2 2 M hgbam c Hydrogenobyrinate a,c diamide c mol · l 1 – – − 2 2 M hgbyr c Hydrogenobyrinate c mol · l 1 – – − 2 2 M his DASH L c L-Histidine c mol · l 1 – – − 2 2 M his DASH L e L-Histidine e mol · l 1 – – −1 2 2 rdcdby Produced M hisp c L-Histidinol phosphate c mol · l – – − 2 2 M histd c L-Histidinol c mol · l 1 – – − 2 2 M hmbil c Hydroxymethylbilane c mol · l 1 – – − 2 2 M hmocta c hexa-methyl octacosanoate c mol · l 1 – – − 2 2 M hmtria c hexa-methyl triacontanoic acid (C30:0, c mol · l 1 – – SBML plus 6 methyl branches) 2 2 −1 2 2

2 M hom DASH L c L-Homoserine c mol · l – – L A − T · 1 E M homtta c 10 hydroxy octa-methyl tetracontatri- c mol l – – X cosanoic acid (C34:0, 8 methyl-branched 2 2 carbons, 1 hydroxylated carbon) 2 2 M hpglu c Tetrahydropteroyltri-L-glutamate c mol · l−1 – – M hpmdtria c hepta-methyl dotriacontanoic acid (7 c mol · l−1 – – methyl branches) 2 2 − 2 2 M hpmtria c hepta-methyl triacontanoic acid (C30:0, c mol · l 1 – – plus 7 methyl branches) − 2 2 M hxan c Hypoxanthine c mol · l 1 – – M iacgam c 1D-myo-inositol 2-Acetamido-2-deoxy- c mol · l−1 – – D-glucopyranoside 2 2 − 2 2 M iasp c Iminoaspartate c mol · l 1 – – M ichor c Isochorismate c mol · l−1 – – 2 2 2 2 Id Name Compartment Derived Unit Constant Boundary Condi- tion M icit c Isocitrate c mol · l−1 – – M id3acald c Indole-3-acetaldehyde c mol · l−1 – – − 2 2 M id3acald e Indole-3-acetaldehyde e mol · l 1 – – − 2 2 M idp c IDP c mol · l 1 – – − 2 2 M igam c 1D-myo-inositol 2-deoxy-D- c mol · l 1 – – glucopyranoside 2 2 − 2 2 M ile DASH L c L-Isoleucine c mol · l 1 – – −1 rdcdby Produced M ile DASH L e L-Isoleucine e mol · l – – − 2 2 M imacp c 3-(Imidazol-4-yl)-2-oxopropyl phosphate c mol · l 1 – – − 2 2 M imp c IMP c mol · l 1 – – − 2 2 M indole c Indole c mol · l 1 – – − 2 2 M indpyr c Indolepyruvate c mol · l 1 – – SBML − 2 2 M inost c myo-Inositol c mol · l 1 – – −1 2 2

2 M ins c Inosine c mol · l – – L A − T · 1 2 2 E M ipdp c Isopentenyl diphosphate c mol l – –

X − 2 2 M itp c ITP c mol · l 1 – – − 2 2 M k c potassium c mol · l 1 – – − 2 2 M k e potassium e mol · l 1 – – − 2 2 M kmeroacidACP c keto meroacid ACP c mol · l 1 – – − 2 2 M- cyclopropanated keto-meroacid ACP (1 c mol · l 1 – – kmeroacidcyc1ACP- cyclopropane ring) 2 2 c 2 2 M- cyclopropanated keto-meroacid ACP (2 c mol · l−1 – – kmeroacidcyc2ACP- cyclopropane rings) c 2 2 23 24 Id Name Compartment Derived Unit Constant Boundary Condi- tion M- cyclopropanated keto-meroacid AMP (2 c mol · l−1 – – kmeroacidcyc2AMP- cyclopropane rings) c 2 2 M kmycolate c keto mycolate (2 cyclopropanated rings) c mol · l−1 – – M lac DASH L c L-Lactate c mol · l−1 – – − 2 2 M lac DASH L e L-Lactate e mol · l 1 – – − 2 2 M lald DASH L c L-Lactaldehyde c mol · l 1 – – −1 2 2 rdcdby Produced M lcts c Lactose c mol · l – – − 2 2 M lcts e Lactose e mol · l 1 – – − 2 2 M leu DASH L c L-Leucine c mol · l 1 – – − 2 2 M leu DASH L e L-Leucine e mol · l 1 – – − 2 2 M lpam c Lipoamide c mol · l 1 – – SBML − 2 2 M lpro c Lipoylprotein c mol · l 1 – – −1 2 2

2 M lys DASH L c L-Lysine c mol · l – – L A − T · 1 2 2 E M lys DASH L e L-Lysine e mol l – –

X − 2 2 M m1ocdca c methyl octadecanoate c mol · l 1 – – − 2 2 M malACP c Malonyl-[acyl-carrier protein] c mol · l 1 – – − 2 2 M mal DASH L c L-Malate c mol · l 1 – – − 2 2 M mal DASH L e L-Malate e mol · l 1 – – − 2 2 M malcoa c Malonyl-CoA c mol · l 1 – – − 2 2 M malt c Maltose c mol · l 1 – – − 2 2 M malt e Maltose e mol · l 1 – – − 2 2 M malthp c Maltoheptaose c mol · l 1 – – − 2 2 M malthp e Maltoheptaose e mol · l 1 – – − 2 2 M maltpt c Maltopentaose c mol · l 1 – – − 2 2 M man1p c D-Mannose 1-phosphate c mol · l 1 – – − 2 2 M man6p c D-Mannose 6-phosphate c mol · l 1 – – 2 2 2 2 Id Name Compartment Derived Unit Constant Boundary Condi- tion M man c D-Mannose c mol · l−1 – – M marach c methyl arachidic acid c mol · l−1 – – − 2 2 M mbhn c methyl behenic acid c mol · l 1 – – − 2 2 M mcbts c mycobactin S c mol · l 1 – – − 2 2 M mcbtt c mycobactin T c mol · l 1 – – − 2 2 M meoh c Methanol c mol · l 1 – – − 2 2 M meoh e Methanol e mol · l 1 – – −1 2 2 rdcdby Produced M meroacidACP c alpha meroacid ACP c mol · l – – − 2 2 M- cyclopropanated alpha meroacid ACP (1 c mol · l 1 – – meroacidcyc1ACP c cyclopropane ring) 2 2 − 2 2 M- cyclopropanated alpha meroacid ACP (2 c mol · l 1 – – meroacidcyc2ACP c cyclopropane rings) SBML − 2 2 M- cyclopropanated alpha meroacid AMP (2 c mol · l 1 – –

2 meroacidcyc2AMP c cyclopropane rings) L A − T · 1 2 2 E M met DASH L c L-Methionine c mol l – – X M met DASH L e L-Methionine e mol · l−1 – – − 2 2 M methf c 5,10-Methenyltetrahydrofolate c mol · l 1 – – − 2 2 M metsox DASH R- L-methionine-R-sulfoxide c mol · l 1 – – DASH L c 2 2 − 2 2 M metsox DASH S- L-Methionine Sulfoxide c mol · l 1 – – DASH L c − 2 2 M mettrna c L-Methionyl-tRNA (Met) c mol · l 1 – – M mfrrppdima c phenolic glycolipid (Mtb) c mol · l−1 – – − 2 2 M mg2 c magnesium c mol · l 1 – – − 2 2 M mg2 e magnesium e mol · l 1 – – − 2 2 M mharab DASH D c mannose capped hexa arabinofuranoside c mol · l 1 – –

25 − 2 2 M mhpglu c 5-Methyltetrahydropteroyltri-L-glutamate c mol · l 1 – – 2 2 2 2 26 Id Name Compartment Derived Unit Constant Boundary Condi- tion M mi1p DASH D c 1D-myo-Inositol 1-phosphate c mol · l−1 – – M mi3p DASH D c 1D-myo-Inositol 3-phosphate c mol · l−1 – – − 2 2 M mi4p DASH D c 1D-myo-Inositol 4-phosphate c mol · l 1 – – − 2 2 M mkmeroacidACP c methyl hydroxy keto meroacid ACP (1 cy- c mol · l 1 – – clopropane ring) 2 2 − 2 2 M- cyclopropanated methyl hydroxy keto c mol · l 1 – – mkmeroacidcyc1ACP- meroacid ACP (1 cyclopropane ring) 2 2 rdcdby Produced c M- cyclopropanated methyl hydroxy keto c mol · l−1 – – mkmeroacidcyc1AMP- meroacid AMP (1 cyclopropane ring) c 2 2 M mkmycolate c keto mycolate (1 cyclopropanated rings) c mol · l−1 – – SBML M mlthf c 5,10-Methylenetetrahydrofolate c mol · l−1 – – −1 2 2

2 M mmcoa DASH R c (R)-Methylmalonyl-CoA c mol · l – – L A − T · 1 2 2 E M mmcoa DASH S c (S)-Methylmalonyl-CoA c mol l – –

X − 2 2 M mmeroacidACP c methoxy meroacid ACP c mol · l 1 – – − 2 2 M- cyclopropanated methoxy-meroacid ACP c mol · l 1 – – mmeroacidcyc1ACP- (1 cyclopropane ring) 2 2 c 2 2 M- cyclopropanated methoxy-meroacid ACP c mol · l−1 – – mmeroacidcyc2ACP- (2 cyclopropane rings) c 2 2 M- cyclopropanated methoxy-meroacid AMP c mol · l−1 – – mmeroacidcyc2AMP- (2 cyclopropane rings) c 2 2 M mmmeroacidACP c methyl hydroxy methoxy meroacid ACP c mol · l−1 – – 2 2 Id Name Compartment Derived Unit Constant Boundary Condi- tion M- cyclopropanated methyl hydroxy methoxy c mol · l−1 – – mmmeroacidcyc1ACP- meroacid ACP (1 cyclopropane ring) c 2 2 M- cyclopropanated methyl hydroxy methoxy c mol · l−1 – – mmmeroacidcyc1AMP- meroacid AMP (1 cyclopropane ring) c 2 2 M mmmycolate c methoxy mycolate (1 cyclopropanated c mol · l−1 – –

rdcdby Produced ring) − 2 2 M mmycolate c methoxy mycolate (2 cyclopropanated c mol · l 1 – – rings) − 2 2 M mndn c menadione c mol · l 1 – – M mocdca c 10-methylstearic acid c mol · l−1 – – SBML − 2 2 M motre c maltooligosyltrehalose c mol · l 1 – – −1 2 2

2 M mppp9 c Magnesium protoporphyrin c mol · l – – L A − T · 1 2 2 E M mql6 c Menaquinol 6 c mol l – –

X − 2 2 M mql8 c Menaquinol 8 c mol · l 1 – – − 2 2 M mqn6 c Menaquinone 6 c mol · l 1 – – − 2 2 M mqn8 c Menaquinone 8 c mol · l 1 – – − 2 2 M msa c Malonate semialdehyde c mol · l 1 – – − 2 2 M msh c mycothiol (reduced) c mol · l 1 – – − 2 2 M mshfald c mycothiol conjugated methanol c mol · l 1 – – − 2 2 M mshfaldox c mycothiol conjugated aldehyde c mol · l 1 – – − 2 2 M mssg c mycothiol (oxidized - dimer) c mol · l 1 – – − 2 2 M mstrACP c 10methyl stearyoyl-ACP c mol · l 1 – – − 2 2 M mycolate c mycolate (2 cyclopropanated rings) c mol · l 1 – – − 2 2 M na1 c Sodium c mol · l 1 – –

27 − 2 2 M na1 e Sodium e mol · l 1 – – 2 2 2 2 28 Id Name Compartment Derived Unit Constant Boundary Condi- tion M nac c Nicotinate c mol · l−1 – – M nad c Nicotinamide adenine dinucleotide c mol · l−1 – – − 2 2 M nadh c Nicotinamide adenine dinucleotide - re- c mol · l 1 – – duced 2 2 − 2 2 M nadp c Nicotinamide adenine dinucleotide phos- c mol · l 1 – – phate − 2 2 M nadph c Nicotinamide adenine dinucleotide phos- c mol · l 1 – –

rdcdby Produced phate - reduced − 2 2 M ncam c Nicotinamide c mol · l 1 – – M nh4 c Ammonium c mol · l−1 – – − 2 2 M nh4 e Ammonium e mol · l 1 – – − 2 2 M nh4oh c Ammonium hydroxide c mol · l 1 – – SBML − 2 2 M nicrnt c Nicotinate D-ribonucleotide c mol · l 1 – – −1 2 2

2 M no2 c Nitrite c mol · l – – L A − T · 1 2 2 E M no2 e Nitrite e mol l – –

X − 2 2 M no3 c Nitrate c mol · l 1 – – − 2 2 M no3 e Nitrate e mol · l 1 – – − 2 2 M no c Nitric oxide c mol · l 1 – – − 2 2 M no e Nitric oxide e mol · l 1 – – − 2 2 M o2 c O2 c mol · l 1 – – − 2 2 M o2 e O2 e mol · l 1 – – − 2 2 M o2s c Superoxide anion c mol · l 1 – – − 2 2 M oaa c Oxaloacetate c mol · l 1 – – − 2 2 M occoa c Octanoyl-CoA (n-C8:0CoA) c mol · l 1 – – − 2 2 M ocdca c octadecanoate (n-C18:0) c mol · l 1 – – − 2 2 M ocdca e octadecanoate (n-C18:0) e mol · l 1 – – − 2 2 M ocdcea c octadecenoate (n-C18:1) c mol · l 1 – – 2 2 2 2 Id Name Compartment Derived Unit Constant Boundary Condi- tion M octa c octanoate (n-C8:0) c mol · l−1 – – M octdp c all-trans-Octaprenyl diphosphate c mol · l−1 – – − 2 2 M odecoa c Octadecenoyl-CoA (n-C18:1CoA) c mol · l 1 – – − 2 2 M ohpb c 2-Oxo-3-hydroxy-4-phosphobutanoate c mol · l 1 – – − 2 2 M omdtria c octa-methyl dotriacontanoic acid (C32:0 c mol · l 1 – – with 7 methyl branches) 2 2 − 2 2 M omtta c octa-methyl tetracontatricosanoic acid c mol · l 1 – –

rdcdby Produced (C34:0, 8 methyl-branched carbons) − 2 2 M orn c Ornithine c mol · l 1 – – M orn e Ornithine e mol · l−1 – – − 2 2 M orot5p c Orotidine 5’-phosphate c mol · l 1 – – − 2 2 M orot c Orotate c mol · l 1 – – SBML − 2 2 M oxa c Oxalate c mol · l 1 – – −1 2 2

2 M oxalcoa c Oxalyl-CoA c mol · l – – L A − T · 1 2 2 E M pa160190 c 1,2-sn-glycerol 3-phosphate c mol l – –

X − 2 2 M pa160 c 1,2-dihexadecanoyl-sn-glycerol 3- c mol · l 1 – – phosphate 2 2 − 2 2 M pa190190 c 1,2-sn-glycerol 3-phosphate c mol · l 1 – – M pac c Phenylacetic acid c mol · l−1 – – − 2 2 M pac e Phenylacetic acid e mol · l 1 – – − 2 2 M pacald c Phenylacetaldehyde c mol · l 1 – – − 2 2 M palmACP c Palmitoyl-ACP (n-C16:0ACP) c mol · l 1 – – − 2 2 M pan4p c Pantetheine 4’-phosphate c mol · l 1 – – − 2 2 M pant DASH R c (R)-Pantoate c mol · l 1 – – − 2 2 M pap c Adenosine 3’,5’-bisphosphate c mol · l 1 – – − 2 2 M paps c 3’-Phosphoadenylyl sulfate c mol · l 1 – –

29 − 2 2 M pat c penta-acyl trehalose c mol · l 1 – – 2 2 2 2 30 Id Name Compartment Derived Unit Constant Boundary Condi- tion M pdima c phthiocerol dimycocerosate A (Mtb) c mol · l−1 – – M pdima e phthiocerol dimycocerosate A (Mtb) e mol · l−1 – – − 2 2 M pdx5p c Pyridoxine 5’-phosphate c mol · l 1 – – − 2 2 M pe160 c phosphatidylethanolamine (dihexade- c mol · l 1 – – canoyl, n-C16:0) 2 2 − 2 2 M pe180 c phosphatidylethanolamine (dioctade- c mol · l 1 – – canoyl, n-C18:0) −1 2 2 rdcdby Produced M peamn c Phenethylamine c mol · l – – M pep c Phosphoenolpyruvate c mol · l−1 – – − 2 2 M peptido EC c Peptidoglycan subunit of Escherichia coli c mol · l 1 – – − 2 2 M peptido TB1 c peptidoglycan subunit (for Mycobac- c mol · l 1 – – terium tuberculosis) 2 2 SBML − 2 2 M peptido TB2 c peptidoglycan subunit (for Mycobac- c mol · l 1 – –

2 terium tuberculosis) L A − T · 1 2 2 E M pg160190 c Phosphatidylglycerol (hexadecanoyl, c mol l – – X methylstearoyl) − 2 2 M pg160 c Phosphatidylglycerol (dihexadecanoyl, n- c mol · l 1 – – C16:0) − 2 2 M pg190 c Phosphatidylglycerol (dimethylstearoyl, c mol · l 1 – – C19:0) − 2 2 M pgp160190 c Phosphatidylglycerophosphate (hex- c mol · l 1 – – adecanoyl, tuberculostearoyl, C16:0, C19:0) 2 2 M pgp160 c Phosphatidylglycerophosphate (dihexade- c mol · l−1 – – canoyl, n-C16:0) − 2 2 M pgp190 c Phosphatidylglycerophosphate (dituber- c mol · l 1 – – culostearoyl, C19:0) 2 2 Id Name Compartment Derived Unit Constant Boundary Condi- tion M phdcaACP c phenol palmitic acid ACP c mol · l−1 – – M phdca c phenol palmitic acid c mol · l−1 – – − 2 2 M phdca e phenol palmitic acid e mol · l 1 – – − 2 2 M phdcacoa c phenol palmitic coenzyme A c mol · l 1 – – − 2 2 M phe DASH L c L-Phenylalanine c mol · l 1 – – − 2 2 M phe DASH L e L-Phenylalanine e mol · l 1 – – − 2 2 M pheme c Protoheme c mol · l 1 – – −1 2 2 rdcdby Produced M phom c O-Phospho-L-homoserine c mol · l – – − 2 2 M phpyr c Phenylpyruvate c mol · l 1 – – − 2 2 M phthcl c phthiocol (oxidized) c mol · l 1 – – − 2 2 M phthclh2 c phthiocol (reduced) c mol · l 1 – – − 2 2 M phthdl c phthiodolone c mol · l 1 – – SBML − 2 2 M phthiocerol c phthiocerol A c mol · l 1 – – −1 2 2

2 M phthr c O-Phospho-4-hydroxy-L-threonine c mol · l – – L A − T · 1 2 2 E M pi c Phosphate c mol l – –

X − 2 2 M pi e Phosphate e mol · l 1 – – − 2 2 M pmcoa c Pimeloyl-CoA c mol · l 1 – – − 2 2 M pmhexc c penta-methyl hexacosanoate c mol · l 1 – – − 2 2 M pmocta c penta-methyl octacosanoate c mol · l 1 – – − 2 2 M pmtcoa c Palmitoyl-CoA (n-C16:0CoA) c mol · l 1 – – − 2 2 M pnto DASH R c (R)-Pantothenate c mol · l 1 – – − 2 2 M ppa c Propionate (n-C3:0) c mol · l 1 – – − 2 2 M ppa e Propionate (n-C3:0) e mol · l 1 – – − 2 2 M ppal c Propanal c mol · l 1 – – − 2 2 M ppbng c Porphobilinogen c mol · l 1 – – − 2 2 M ppcoa c Propanoyl-CoA c mol · l 1 – –

31 − 2 2 M ppdima c phenol phthiocerol dimycocerosate (Mtb) c mol · l 1 – – 2 2 2 2 32 Id Name Compartment Derived Unit Constant Boundary Condi- tion M ppdima e phenol phthiocerol dimycocerosate (Mtb) e mol · l−1 – – M pphn c Prephenate c mol · l−1 – – − 2 2 M pphthdl c phenolic phthiodiolone c mol · l 1 – – − 2 2 M pphthiocerol c phenolphtiocerol c mol · l 1 – – − 2 2 M ppi c Diphosphate c mol · l 1 – – − 2 2 M ppp9 c Protoporphyrin c mol · l 1 – – − 2 2 M pppg9 c Protoporphyrinogen IX c mol · l 1 – – −1 2 2 rdcdby Produced M pppi c Inorganic triphosphate c mol · l – – − 2 2 M pram c 5-Phospho-beta-D-ribosylamine c mol · l 1 – – − 2 2 M pran c N-(5-Phospho-D-ribosyl)anthranilate c mol · l 1 – – − 2 2 M prbamp c 1-(5-Phosphoribosyl)-AMP c mol · l 1 – – − 2 2 M prbatp c 1-(5-Phosphoribosyl)-ATP c mol · l 1 – – SBML − 2 2 M pre2 c dihydrosirohydrochlorin c mol · l 1 – – −1 2 2

2 M pre3a c Precorrin 3 A c mol · l – – L A − T · 1 2 2 E M pre3b c Precorrin 3B c mol l – –

X − 2 2 M pre4 c Precorrin 4 c mol · l 1 – – − 2 2 M pre5 c Precorrin 5 c mol · l 1 – – − 2 2 M pre6a c Precorrin 6A c mol · l 1 – – − 2 2 M pre6b c Precorrin 6B c mol · l 1 – – − 2 2 M pre8 c Precorrin 8 c mol · l 1 – – − 2 2 M prephthACP c phthiocerol precursor bound ACP c mol · l 1 – – − 2 2 M prephth c phthiocerol precursor c mol · l 1 – – − 2 2 M prephthcoa c phthiocerol precursor bound coenzyme A c mol · l 1 – – − 2 2 M prepphthACP c phenolic phthiocerol precursor bound c mol · l 1 – – ACP 2 2 − 2 2 M prepphth c phenolic phthiocerol precursor c mol · l 1 – – 2 2 Id Name Compartment Derived Unit Constant Boundary Condi- tion M prfp c 1-(5-Phosphoribosyl)-5-[(5- c mol · l−1 – – phosphoribosylamino)methylideneamino]imidazole- 4-carboxamide 2 2 M prlp c 5-[(5-phospho-1-deoxyribulos-1- c mol · l−1 – – ylamino)methylideneamino]-1-(5- phosphoribosyl)imidazole-4-carboxamide 2 2 M pro DASH L c L-Proline c mol · l−1 – – −1 rdcdby Produced M pro DASH L e L-Proline e mol · l – – − 2 2 M prpp c 5-Phospho-alpha-D-ribose 1-diphosphate c mol · l 1 – – − 2 2 M ps160 c phosphatidylserine (dihexadecanoyl, n- c mol · l 1 – – C16:0) 2 2 − 2 2 M ps180 c phosphatidylserine (dioctadecanoyl, n- c mol · l 1 – – SBML C18:0) −1 2 2

2 M psd5p c Pseudouridine 5’-phosphate c mol · l – – L A − T · 1 E M pser DASH L c O-Phospho-L-serine c mol l – –

X − 2 2 M ptcys c N-Pantothenoylcysteine c mol · l 1 – – − 2 2 M ptd1ino160190 c phosphatidyl 1D myo inositol (C16:0, c mol · l 1 – – C19:0) 2 2 − 2 2 M ptd1ino160 c phosphatidyl 1D myo inositol c mol · l 1 – – M ptrc c Putrescine c mol · l−1 – – − 2 2 M ptth c Pantetheine c mol · l 1 – – − 2 2 M pyam5p c Pyridoxamine 5’-phosphate c mol · l 1 – – − 2 2 M pydam c Pyridoxamine c mol · l 1 – – − 2 2 M pydx5p c Pyridoxal 5’-phosphate c mol · l 1 – – − 2 2 M pydx c Pyridoxal c mol · l 1 – – − 2 2 M pydxn c Pyridoxine c mol · l 1 – –

33 − 2 2 M pyr c Pyruvate c mol · l 1 – – 2 2 2 2 34 Id Name Compartment Derived Unit Constant Boundary Condi- tion M pyr e Pyruvate e mol · l−1 – – M q8 c Ubiquinone-8 c mol · l−1 – – − 2 2 M q8h2 c Ubiquinol-8 c mol · l 1 – – − 2 2 M q c Ubiquinone c mol · l 1 – – − 2 2 M qh2 c Ubiquinol c mol · l 1 – – − 2 2 M quln c Quinolinate c mol · l 1 – – − 2 2 M r1p c alpha-D-Ribose 1-phosphate c mol · l 1 – – −1 2 2 rdcdby Produced M r5p c alpha-D-Ribose 5-phosphate c mol · l – – − 2 2 M ragund c rhamanosyl-N-acetylglucosamyl- c mol · l 1 – – undecaprenyl diphosphate 2 2 − 2 2 M rbl DASH D c D-Ribulose c mol · l 1 – – M rbl DASH L c L-Ribulose c mol · l−1 – – SBML − 2 2 M rdmbzi c N1-(alpha-D-ribosyl)-5,6- c mol · l 1 – – 2 2

2 dimethylbenzimidazole L A − T · 1 2 2 E M rhcys c S-Ribosyl-L-homocysteine c mol l – – X M rib DASH D c D-Ribose c mol · l−1 – – − 2 2 M rib DASH D e D-Ribose e mol · l 1 – – − 2 2 M ribflv c Riboﬂavin c mol · l 1 – – − 2 2 M rmyc c mycolate compounds (all) c mol · l 1 – – − 2 2 M rppdima c rhamnose phenol phthiocerol dimyco- c mol · l 1 – – cerosate (Mtb) 2 2 − 2 2 M rrppdima c rhamnose rhamnose phenol phthiocerol c mol · l 1 – – dimycocerosate (Mtb) − 2 2 M ru5p DASH D c D-Ribulose 5-phosphate c mol · l 1 – – M ru5p DASH L c L-Ribulose 5-phosphate c mol · l−1 – – − 2 2 M s7p c Sedoheptulose 7-phosphate c mol · l 1 – – − 2 2 M s c Sulfur c mol · l 1 – – 2 2 2 2 Id Name Compartment Derived Unit Constant Boundary Condi- tion M salc c Salicylate c mol · l−1 – – M sbzcoa c O-Succinylbenzoyl-CoA c mol · l−1 – – − 2 2 M scl2 c sirohydrochlorin 2 c mol · l 1 – – − 2 2 M scl c sirohydrochlorin c mol · l 1 – – − 2 2 M sdhlam c S-Succinyldihydrolipoamide c mol · l 1 – – − 2 2 M selcys c Selenocysteine c mol · l 1 – – − 2 2 M seln c Selenide c mol · l 1 – – −1 2 2 rdcdby Produced M ser DASH D c D-Serine c mol · l – – − 2 2 M ser DASH D e D-Serine e mol · l 1 – – − 2 2 M ser DASH L c L-Serine c mol · l 1 – – − 2 2 M ser DASH L e L-Serine e mol · l 1 – – − 2 2 M seramp c L-seryl-AMP c mol · l 1 – – SBML − 2 2 M sheme c Siroheme c mol · l 1 – – −1 2 2

2 M skm5p c Shikimate 5-phosphate c mol · l – – L A − T · 1 2 2 E M skm c Shikimate c mol l – –

X − 2 2 M skm e Shikimate e mol · l 1 – – − 2 2 M sl1 c sulfonated tetra-acyl trehalose c mol · l 1 – – − 2 2 M sl26da c N-Succinyl-LL-2,6-diaminoheptanedioate c mol · l 1 – – − 2 2 M sl2a6o c N-Succinyl-2-L-amino-6- c mol · l 1 – – oxoheptanedioate 2 2 − 2 2 M so3 c Sulﬁte c mol · l 1 – – M so4 c Sulfate c mol · l−1 – – − 2 2 M so4 e Sulfate e mol · l 1 – – − 2 2 M spmd c Spermidine c mol · l 1 – – − 2 2 M ssaltpp c Succinate semialdehyde-thiamin diphos- c mol · l 1 – – phate anion 2 2

35 − 2 2 M stcoa c Stearoyl-CoA (n-C18:0CoA) c mol · l 1 – – 2 2 36 Id Name Compartment Derived Unit Constant Boundary Condi- tion M sucarg c N2-Succinyl-L-arginine c mol · l−1 – – M sucbz c o-Succinylbenzoate c mol · l−1 – – − 2 2 M succ c Succinate c mol · l 1 – – − 2 2 M succ e Succinate e mol · l 1 – – − 2 2 M succoa c Succinyl-CoA c mol · l 1 – – − 2 2 M sucglu c N2-Succinyl-L-glutamate c mol · l 1 – – − 2 2 M sucgsa c N2-Succinyl-L-glutamate 5-semialdehyde c mol · l 1 – – −1 2 2 rdcdby Produced M suchms c O-Succinyl-L-homoserine c mol · l – – − 2 2 M sucorn c N2-Succinyl-L-ornithine c mol · l 1 – – − 2 2 M sucsal c Succinic semialdehyde c mol · l 1 – – − 2 2 M tamhexc c tetra-methyl hexacosanoate c mol · l 1 – – − 2 2 M tamlgnc c tri-methyl lignoceric acid c mol · l 1 – – SBML − 2 2 M tamocta c tetra-methyl octacosanoate c mol · l 1 – – −1 2 2

2 M tarab DASH D c tetra-arabinofuranoside c mol · l – – L A − T · 1 2 2 E M tartr DASH L c L-tartrate c mol l – –

X − 2 2 M tartr DASH L e L-tartrate e mol · l 1 – – − 2 2 M tat c tetra-acyl trehalose c mol · l 1 – – − 2 2 M tcynt c Thiocyanate c mol · l 1 – – − 2 2 M tdcoa c Tetradecanoyl-CoA (n-C14:0CoA) c mol · l 1 – – − 2 2 M tdm1 c trehalose dimycolate (alpha mycolate + c mol · l 1 – – methoxymycolate) 2 2 − 2 2 M tdm2 c trehalose dimycolate (alpha mycolate + c mol · l 1 – – methoxymycolate) − 2 2 M tdm3 c trehalose dimycolate (alpha mycolate + c mol · l 1 – – ketomycolate) − 2 2 M tdm4 c trehalose dimycolate (alpha mycolate + c mol · l 1 – – methoxymycolate) 2 2 Id Name Compartment Derived Unit Constant Boundary Condi- tion M thdp c 2,3,4,5-Tetrahydrodipicolinate c mol · l−1 – – M thf c 5,6,7,8-Tetrahydrofolate c mol · l−1 – – − 2 2 M thfglu c Tetrahydrofolyl-[Glu](2) c mol · l 1 – – − 2 2 M thm c Thiamin c mol · l 1 – – − 2 2 M thmmp c Thiamin monophosphate c mol · l 1 – – − 2 2 M thmpp c Thiamine diphosphate c mol · l 1 – – − 2 2 M thr DASH L c L-Threonine c mol · l 1 – – −1 2 2 rdcdby Produced M thr DASH L e L-Threonine e mol · l – – − 2 2 M thym c Thymine c mol · l 1 – – − 2 2 M thymd c Thymidine c mol · l 1 – – − 2 2 M tmbhn c tri-methyl behenic acid c mol · l 1 – – − 2 2 M tmha1 c tetramycolyl hexaarabinoside (tdm1 + c mol · l 1 – – SBML tdm2 +tre) (Mtb) 2 2 −1 2 2

2 M tmha2 c tetramycolyl hexaarabinoside (tdm1 + c mol · l – – L A T

E tdm3 + tre) (Mtb)

X − 2 2 M tmha3 c tetramycolyl hexaarabinoside (tdm1 + c mol · l 1 – – tdm4 + tre) (Mtb) − 2 2 M tmha4 c tetramycolyl hexaarabinoside (tdm2 + c mol · l 1 – – tdm3 + tre) (Mtb) − 2 2 M tmha5 c tetramycolyl hexaarabinoside (tdm2 + c mol · l 1 – – tdm4 + tre) (Mtb) − 2 2 M tmha6 c tetramycolyl hexaarabinoside (tdm3 + c mol · l 1 – – tdm4 + tre) (Mtb) − 2 2 M tmhexc c tri-methyl hexacosanoate c mol · l 1 – – M tmlgnc c tri-methyl lignoceric acid c mol · l−1 – – − 2 2 M trdox c Oxidized thioredoxin c mol · l 1 – –

37 − 2 2 M trdrd c Reduced thioredoxin c mol · l 1 – – 2 2 2 2 38 Id Name Compartment Derived Unit Constant Boundary Condi- tion M tre6p c alpha,alpha’-Trehalose 6-phosphate c mol · l−1 – – M tre c Trehalose c mol · l−1 – – − 2 2 M tre e Trehalose e mol · l 1 – – − 2 2 M tres c trehalose 2 sulfate c mol · l 1 – – − 2 2 M triat c tri-acyl trehalose c mol · l 1 – – − 2 2 M trnaala c tRNA(Ala) c mol · l 1 – – − 2 2 M trnaglu c tRNA (Glu) c mol · l 1 – – −1 2 2 rdcdby Produced M trp DASH L c L-Tryptophan c mol · l – – − 2 2 M trp DASH L e L-Tryptophan e mol · l 1 – – − 2 2 M tsul c Thiosulfate c mol · l 1 – – − 2 2 M tsul e Thiosulfate e mol · l 1 – – − 2 2 M ttc c tetracosanoate (n-C24:0) c mol · l 1 – – SBML − 2 2 M ttdca c tetradecanoate (n-C14:0) c mol · l 1 – – −1 2 2

2 M ttdca e tetradecanoate (n-C14:0) e mol · l – – L A − T · 1 2 2 E M tyr DASH L c L-Tyrosine c mol l – –

X − 2 2 M tyr DASH L e L-Tyrosine e mol · l 1 – – − 2 2 M uAgl c UDP-N-acetylmuramoyl-L-alanyl-D- c mol · l 1 – – glutamyl-L-lysine 2 2 − 2 2 M uAgla c UDP-N-acetylmuramoyl-L-alanyl-D- c mol · l 1 – – glutamyl-L-lysyl-D-alanyl-D-alanine − 2 2 M uGgl c UDP-N-acetylmuramoyl-L-alanyl- c mol · l 1 – – gamma-D-glutamyl-L-lysine − 2 2 M uGgla c UDP-N-acetylmuramoyl-L-alanyl- c mol · l 1 – – gamma-D-glutamyl-L-lysyl-D-alanyl-D- alanine 2 2 Id Name Compartment Derived Unit Constant Boundary Condi- tion M uaAgla c Undecaprenyl-diphospho-N- c mol · l−1 – – acetylmuramoyl-L-alanyl-D-glutamyl-L- lysyl-D-alanyl-D-alanine 2 2 M uaGgla c Undecaprenyl-diphospho-N- c mol · l−1 – – acetylmuramoyl-L-alanyl-gamma-D- glutamyl-L-lysyl-D-alanyl-D-alanine 2 2 M uaaAgla c Undecaprenyl-diphospho-N- c mol · l−1 – –

rdcdby Produced acetylmuramoyl-(N-acetylglucosamine)- L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D- 2 2 alanine M uaaAgtla c Undecaprenyl-diphospho-N- c mol · l−1 – – acetylmuramoyl-(N-acetylglucosamine)- SBML L-alanyl-D-glutaminyl-L-lysyl-D-alanyl- 2 2

2 D-alanine L A − T · 1 E M uaaGgla c Undecaprenyl-diphospho-N- c mol l – – X acetylmuramoyl-(N-acetylglucosamine)- L-alanyl-gamma-D-glutamyl-L-lysyl-D- 2 2 alanyl-D-alanine M uaaGgtla c Undecaprenyl-diphospho-N- c mol · l−1 – – acetylmuramoyl-(N-acetylglucosamine)- L-alanyl-D-isoglutaminyl-L-lysyl-D- 2 2 alanyl-D-alanine M uaagmda c Undecaprenyl-diphospho-N- c mol · l−1 – – acetylmuramoyl-(N-acetylglucosamine)- L-ala-D-glu-meso-2,6-diaminopimeloyl- 2 2 D-ala-D-ala 39 40 Id Name Compartment Derived Unit Constant Boundary Condi- tion M uaagtmda c Undecaprenyl-diphospho-N- c mol · l−1 – – acetylmuramoyl-(N-acetylglucosamine)- L-alanyl-D-glutaminyl-meso-2,6- 2 2 diaminopimeloyl-D-alanyl-D-alanine M uaccg c UDP-N-acetyl-3-O-(1-carboxyvinyl)-D- c mol · l−1 – – glucosamine − 2 2 M uacgam c UDP-N-acetyl-D-glucosamine c mol · l 1 – – −1 rdcdby Produced M uagmda c Undecaprenyl-diphospho-N- c mol · l – – acetylmuramoyl-L-alanyl-D-glutamyl- 2 2 meso-2,6-diaminopimeloyl-D-alanyl-D- 2 2 alanine M uama c UDP-N-acetylmuramoyl-L-alanine c mol · l−1 – – SBML M uamag c UDP-N-acetylmuramoyl-L-alanyl-D- c mol · l−1 – – 2 2

2 glutamate L A − T · 1 2 2 E M uamr c UDP-N-acetylmuramate c mol l – – X M udcpdp c Undecaprenyl diphosphate c mol · l−1 – – − 2 2 M udcpp c Undecaprenyl phosphate c mol · l 1 – – − 2 2 M udp c UDP c mol · l 1 – – − 2 2 M udpg c UDPglucose c mol · l 1 – – − 2 2 M udpgal c UDPgalactose c mol · l 1 – – − 2 2 M udpgalfur c UDP-D-galacto-1,4-furanose c mol · l 1 – – − 2 2 M udpglcur c UDP-D-glucuronate c mol · l 1 – – − 2 2 M ugagmda c Undecaprenyl-diphospho- c mol · l 1 – – N-glycolylmuramoyl-(N- 2 2 acetylglucosamine)-L-ala-D-glu-meso- 2 2 2,6-diaminopimeloyl-D-ala-D-ala Id Name Compartment Derived Unit Constant Boundary Condi- tion M ugggmda c Undecaprenyl-diphospho-N- c mol · l−1 – – glycolylmuramoyl-L-alanyl-D-glutamyl- meso-2,6-diaminopimeloyl-D-alanyl-D- 2 2 alanine M uggmd c UDP-N-glycolylmuramoyl-L-alanyl- c mol · l−1 – – D-gamma-glutamyl-meso-2,6- diaminopimelate 2 2 −1 rdcdby Produced M uggmda c UDP-N-glycolylmuramoyl-L-alanyl-D- c mol · l – – glutamyl-meso-2,6-diaminopimeloyl-D- alanyl-D-alanine 2 2 M ugma c UDP-N-glycolylmuramoyl-L-alanine c mol · l−1 – – M ugmag c UDP-N-glycolylmuramoyl-L-alanyl-D- c mol · l−1 – – SBML glutamate 2 2 −1 2 2

2 M ugmd c UDP-N-acetylmuramoyl-L-alanyl- c mol · l – – L A T

E D-gamma-glutamyl-meso-2,6- X diaminopimelate 2 2 M ugmda c UDP-N-acetylmuramoyl-L-alanyl-D- c mol · l−1 – – glutamyl-meso-2,6-diaminopimeloyl-D- alanyl-D-alanine 2 2 M ugmr c UDP-N-glycolylmuramate c mol · l−1 – – M ump c UMP c mol · l−1 – – − 2 2 M unaga c Undecaprenyl diphospho N-acetyl- c mol · l 1 – – glucosamine 2 2 − 2 2 M uppg1 c Uroporphyrinogen I c mol · l 1 – – M uppg3 c Uroporphyrinogen III c mol · l−1 – – − 2 2 M ura c Uracil c mol · l 1 – –

41 − 2 2 M urea c Urea c mol · l 1 – – 2 2 2 2 42 Id Name Compartment Derived Unit Constant Boundary Condi- tion M uri c Uridine c mol · l−1 – – M utp c UTP c mol · l−1 – – − 2 2 M val DASH L c L-Valine c mol · l 1 – – − 2 2 M val DASH L e L-Valine e mol · l 1 – – − 2 2 M xan c Xanthine c mol · l 1 – – − 2 2 M xmp c Xanthosine 5’-phosphate c mol · l 1 – – − 2 2 M xtsn c Xanthosine c mol · l 1 – – −1 2 2 rdcdby Produced M xu5p DASH D c D-Xylulose 5-phosphate c mol · l – – − 2 2 M xyl DASH D c D-Xylose c mol · l 1 – – − 2 2 M xyl DASH D e D-Xylose e mol · l 1 – – − 2 2 M xylu DASH D c D-Xylulose c mol · l 1 – – 2 2

SBML 2 2 2 L A T E X 5 Parameters

This model contains 19 global parameters.

Table 4: Properties of each parameter. Id Name SBO Value Unit Constant cobra- 0000626 −999999.00 mmol · g−1 · default lb (3600 s)−1 cobra- 0000626 999999.00 mmol · g−1 · 2 default ub (3600 s)−1 cobra 0- 0000626 0.00 mmol · g−1 · 2 bound (3600 s)−1 R EX ca2 e- 0000625 −1.00 mmol · g−1 · 2 lower bound (3600 s)−1 R EX cit e- 0000625 −1.00 mmol · g−1 · 2 lower bound (3600 s)−1 R EX cl e- 0000625 −1.00 mmol · g−1 · 2 lower bound (3600 s)−1 R EX cu2 e- 0000625 −1.00 mmol · g−1 · 2 lower bound (3600 s)−1 R EX fe3 e- 0000625 −1.00 mmol · g−1 · 2 lower bound (3600 s)−1 R EX glc- 0000625 −1.00 mmol · g−1 · 2 DASH D e- (3600 s)−1 lower bound 2 R EX glu- 0000625 −1.00 mmol · g−1 · DASH L e- (3600 s)−1 lower bound 2 R EX glyc e- 0000625 −1.00 mmol · g−1 · lower bound (3600 s)−1 R EX h2o e- 0000625 −1.00 mmol · g−1 · 2 lower bound (3600 s)−1 R EX h e- 0000625 −1.00 mmol · g−1 · 2 lower bound (3600 s)−1 R EX k e- 0000625 −1.00 mmol · g−1 · 2 lower bound (3600 s)−1 R EX na1 e- 0000625 −1.00 mmol · g−1 · 2 lower bound (3600 s)−1 R EX nh4 e- 0000625 −1.00 mmol · g−1 · 2 lower bound (3600 s)−1 R EX o2 e- 0000625 −0.98 mmol · g−1 · 2 lower bound (3600 s)−1 2

Produced by SBML2LATEX 43 Id Name SBO Value Unit Constant R EX pi e- 0000625 −1.00 mmol · g−1 · lower bound (3600 s)−1 R EX so4 e- 0000625 −1.00 mmol · g−1 · 2 lower bound (3600 s)−1 2

44 Produced by SBML2LATEX 6 Reactions

This model contains 1025 reactions. All reactions are listed in the following table and are subsequently described in detail. If a reaction is affected by a modiﬁer, the identiﬁer of this species is written above the reaction arrow.

Table 5: Overview of all reactions o N¯ Id Name Reaction Equation SBO 1 R 2AGPEAT160 2-acyl-glycerophospho-ethanolamine acyl- M 2agpe160 c + M atp c + transferase (n-C16:0) M hdca c −→ M amp c + M pe160 c + M ppi c 2 R 2AGPEAT180 2-acyl-glycerophospho-ethanolamine acyl- M 2agpe180 c + M atp c + rdcdby Produced transferase (n-C18:0) M ocdca c −→ M amp c + M pe180 c + M ppi c 3 R 4HTHRS 4-Hydroxy-L-threonine synthase M h2o c + M phthr c −→ M 4hthr c + M pi c 4 R 5DGLCNR 5-dehydro-D-gluconate reductase M 5dglcn c + M h c + M nadph c )−−−−* M glcn c + M nadp c

SBML 5 R AACPS10 acyl-[acyl-carrier-protein] synthetase (tuber- M ACP c + M atp c +

culostearic acid) M mocdca c −→ M amp c + M mstrACP c + 2 L

A M ppi c T E

X 6 R AACPS11 acyl-[acyl-carrier-protein] synthetase M 4hbz c + M ACP c + M atp c −→ M 4hbzACP c + M amp c + M ppi c 7 R AACPS3 acyl-[acyl-carrier-protein] synthetase (n- M ACP c + M atp c + M hdca c −→ M amp c + C16:0) M palmACP c + M ppi c 8 R ABTA 4-aminobutyrate transaminase M 4abut c + M akg c −→ M glu DASH L c + M sucsal c 9 R ACACCT acetyl-CoA:acetoacetyl-CoA transferase M acac c + M accoa c −→ M aacoa c + M ac c 10 R ACACT1r acetyl-CoA C-acetyltransferase 2 M accoa c )−−−−* M aacoa c + M coa c 11 R ACALDi acetaldehyde dehydrogenase (acetylating) M acald c + M coa c + M nad c −→ M accoa c + M h c + M nadh c 12 R ACBIPGT Adenosyl cobinamide phosphate guanyltrans- M adocbip c + M gtp c + ferase M h c −→ M agdpcbi c + M ppi c 45 46 o N¯ Id Name Reaction Equation SBO 13 R ACCC Acyl-CoA Carboxylase M co2 c + M hexccoa c −→ M chexccoa c + M h2o c 14 R ACCOACr acetyl-CoA carboxylase, reversible reaction M accoa c + M atp c + M hco3 c )−−−−* M adp c + M h c + M malcoa c + M pi c 15 R ACChex Hexanoic Acid CoA Ligase M coa c + M h c + M hexc c −→ M h2o c + M hexccoa c 16 R ACGAMPM phosphoacetylglucosamine mutase M acgam6p c )−−−−* M acgam1p c 17 R ACGAMT UDP-N-acetylglucosamine:undecaprenylphosphateM uacgam c + M udcpp c −→ M ump c + N-acetylglucosamine -1-phosphate trans- M unaga c

rdcdby Produced ferase 18 R ACGK acetylglutamate kinase M acglu c + M atp c −→ M acg5p c + M adp c 19 R ACGS N-acetylglutamate synthase M accoa c + M glu DASH L c −→ M acglu c + M coa c + M h c 20 R ACHBS 2-aceto-2-hydroxybutanoate synthase M 2obut c + M h c + M pyr c −→ M 2ahbut c + SBML M co2 c

2 21 R ACKr acetate kinase M ac c + M atp c )−−−−* M actp c + M adp c L A T + −→ + E 22 R ACLS acetolactate synthase M h c 2 M pyr c M alac DASH S c X M co2 c 23 R ACODA acetylornithine deacetylase M acorn c + M h2o c −→ M ac c + M orn c 24 R ACONT aconitase M cit c )−−−−* M icit c 25 R ACOTA acetylornithine transaminase M acorn c + M akg c )−−−−* M acg5sa c + M glu DASH L c 26 R ACP1 FMN acid phosphatase (FMN) M fmn c + M h2o c −→ M pi c + M ribﬂv c 27 R ACPS1 acyl-carrier protein synthase M apoACP c + M coa c −→ M ACP c + M h c + M pap c 28 R ACS acetyl-CoA synthetase M ac c + M atp c + M coa c −→ M accoa c + M amp c + M ppi c 29 R ACS2 acetyl-CoA synthase (propionate) M atp c + M coa c + M ppa c −→ M amp c + M ppcoa c + M ppi c o N¯ Id Name Reaction Equation SBO 30 R ACYSBMNt acysbmn transport (mtb) M acysbmn c )−−−−* M acysbmn e 31 R ADA Adenosine deaminase M adn c + M h2o c + M h c −→ M ins c + M nh4 c 32 R ADCL 4-aminobenzoate synthase M 4adcho c −→ M 4abz c + M h c + M pyr c 33 R ADCPS1 adenosylcobinamide-phosphate synthase M adcobhex c + M appl c + M atp c −→ M adocbi c + M adp c + M h c + M pi c 34 R ADCPS2 adenosylcobinamide-phosphate synthase M adcobhex c + M applp c + M atp c −→ M adocbip c + M adp c + M h c +

rdcdby Produced M pi c 35 R ADCS 4-amino-4-deoxychorismate synthase M chor c + M gln DASH L c −→ M 4adcho c + M glu DASH L c 36 R ADCYRS adenosylcobyric acid synthase (glutamine- M adcobdam c + 4 M atp c + hydrolysing) 4 M gln DASH L c + SBML 4 M h2o c −→ M adcobhex c + 4 M adp c +

2 4 M glu DASH L c + 4 M h c + 4 M pi c L A T + −−* E 37 R ADK1 adenylate kinase M amp c M atp c )−− 2 M adp c X 38 R ADK2 adenylate kinase (Inorganic triphosphate) M amp c + M pppi c )−−−−* M adp c + M ppi c 39 R ADK3 adentylate kinase (GTP) M amp c + M gtp c )−−−−* M adp c + M gdp c 40 R ADK4 adentylate kinase (ITP) M amp c + M itp c )−−−−* M adp c + M idp c 41 R ADMDCr Adenosylmethionine decarboxylase M amet c + M h c )−−−−* M ametam c + M co2 c 42 R ADNCYC adenylate cyclase M atp c −→ M camp c + M ppi c 43 R ADNK1 adenosine kinase M adn c + M atp c −→ M adp c + M amp c + M h c 44 R ADNK3 adenosine kinase M adn c + M gtp c −→ M amp c + M gdp c + M h c 45 R ADNK4 adenosine kinase M adn c + M dgtp c −→ M amp c + M dgdp c + M h c 47 48 o N¯ Id Name Reaction Equation SBO 46 R ADOCBIK Adenosyl cobinamide kinase M adocbi c + M atp c −→ M adocbip c + M adp c + M h c 47 R ADOCBLS Adenosylcobalamin 5’-phosphate synthase M agdpcbi c + M rdmbzi c −→ M adocbl c + M gmp c + M h c 48 R ADPT adenine phosphoribosyltransferase M ade c + M prpp c −→ M amp c + M ppi c 49 R ADSK adenylyl-sulfate kinase M aps c + M atp c −→ M adp c + M h c + M paps c 50 R ADSL1r adenylsuccinate lyase M dcamp c )−−−−* M amp c + M fum c 51 R ADSL2r adenylosuccinate lyase M 25aics c )−−−−* M aicar c + M fum c

rdcdby Produced 52 R ADSS adenylosuccinate synthase M asp DASH L c + M gtp c + M imp c −→ M dcamp c + M gdp c + 2 M h c + M pi c 53 R AFE arabinofuranosyl extension (M tb) M agalfragund c + M arabinan c −→ M arabinanagalfragund c + SBML M h2o c

2 54 R AFTA arabinofuranosyl transferase (M tb) M decda tb c+M galfragund c −→ M agalfragund c+ L A T

E M decd tb c X 55 R AGDC N-acetylglucosamine-6-phosphate deacety- M acgam6p c + M h2o c −→ M ac c + lase M gam6p c 56 R AGMT agmatinase M agm c + M h2o c −→ M ptrc c + M urea c 57 R AGPAT160 1-hexadecanoyl-sn-glycerol 3-phosphate O- M 1hdecg3p c + M palmACP c −→ M ACP c + acyltransferase (n-C16:0) M pa160 c 58 R AGPAT160190 1-hexadecanoyl-sn-glycerol 3-phosphate O- M 1hdecg3p c + M mstrACP c −→ M ACP c + acyltransferase M pa160190 c 59 R AGPAT190 1-hexadecanoyl-sn-glycerol 3-phosphate O- M 1msg3p c + M mstrACP c −→ M ACP c + acyltransferase M pa190190 c 60 R AGPR N-acetyl-g-glutamyl-phosphate reductase M acg5sa c + M nadp c + M pi c )−−−−* M acg5p c + M h c + M nadph c o N¯ Id Name Reaction Equation SBO 61 R AHC adenosylhomocysteinase M ahcys c + M h2o c )−−−−* M adn c + M hcys DASH L c 62 R AHCYSNS S-adenosylhomocysteine nucleosidase M ahcys c + M h2o c −→ M ade c + M rhcys c 63 R AHMMPS 4-amino-5-hydroxymethyl-2- M air c + 2 M h c −→ M 4ahmmp c + methylpyrimidine synthetase M gcald c + M pi c 64 R AICART phosphoribosylaminoimidazolecarboxamide M 10fthf c + M aicar c )−−−−* M fprica c + M thf c formyltransferase 65 R AICART2 phosphoribosylaminoimidazolecarboxamide M aicar c + M atp c + M for c )−−−−* M adp c + formyltransferase 2 M fprica c + M pi c

rdcdby Produced 66 R AIRC2 phosphoribosylaminoimidazole carboxylase M air c + M atp c + M hco3 c −→ M 5caiz c + M adp c + M h c + M pi c 67 R AIRC3 phosphoribosylaminoimidazole carboxylase M 5aizc c )−−−−* M 5caiz c (mutase rxn) 68 R AIRCr phosphoribosylaminoimidazole carboxylase M air c + M co2 c )−−−−* M 5aizc c + M h c SBML 69 R AKGDb oxoglutarate dehydrogenase (dihy- M coa c + M sdhlam c −→ M dhlam c +

2 drolipoamide S-succinyltransferase) M succoa c L A T + −→ E 70 R ALAALAD D-alanine-D-alanine dipeptidase M alaala c M h2o c 2 M ala DASH D c X 71 R ALAALAr D-alanine-D-alanine ligase (reversible) 2 M ala DASH D c + M atp c )−−−−* M adp c + M alaala c + M h c + M pi c 72 R ALAD L L-alanine dehydrogenase M ala DASH L c + M h2o c + M nad c −→ M h c + M nadh c + M nh4 c + M pyr c 73 R ALAR alanine racemase M ala DASH L c )−−−−* M ala DASH D c 74 R ALATA L L-alanine transaminase M akg c+M ala DASH L c )−−−−* M glu DASH L c+ M pyr c 75 R ALATRS Alanyl-tRNA synthetase M ala DASH L c + M atp c + M trnaala c −→ M alatrna c + M amp c + M ppi c 76 R ALAt2r L-alanine reversible transport via proton sym- M ala DASH L e + 49 port M h e )−−−−* M ala DASH L c + M h c 50 o N¯ Id Name Reaction Equation SBO 77 R ALDD1 aldehyde dehydrogenase (formaldehyde, M fald c + M h2o c + M nad c −→ M for c + NAD) 2 M h c + M nadh c 78 R ALDD19x aldehyde dehydrogenase (phenylacetalde- M h2o c + M nad c + M pacald c −→ 2 M h c + hyde, NAD) M nadh c + M pac c 79 R ALDD2x aldehyde dehydrogenase (acetaldehyde, M acald c + M h2o c + M nad c −→ M ac c + NAD) 2 M h c + M nadh c 80 R AMAOTr adenosylmethionine-8-amino-7- M 8aonn c + M amet c )−−−−* M amob c + oxononanoate transaminase M dann c 81 R AMID4 amidase M ad c + M h2o c −→ M ac c + M nh4 c

rdcdby Produced 82 R AMMQT6 S-adenosylmethione M 2dmmq6 c + M amet c −→ M ahcys c + M h c + M mqn6 c 83 R AMMQT8 S-adenosylmethione:2-demthylmenaquinone M 2dmmq8 c + M amet c + methyltransferase (menaquinone 8) M h c −→ M ahcys c + M mql8 c 84 R AMMQT8 2 S-adenosylmethione:2- M 2dmmq8 c + M amet c −→ M ahcys c + SBML demethylmenaquinone methyltransferase M h c + M mqn8 c

2 85 R AMPTASECG alanyl aminopeptidase (cys-gly) M cgly c + M h2o c −→ M cys DASH L c + L A T

E M gly c X 86 R ANPRT anthranilate phosphoribosyltransferase M anth c + M prpp c −→ M ppi c + M pran c 87 R ANS anthranilate synthase M chor c + M gln DASH L c −→ M anth c + M glu DASH L c + M h c + M pyr c 88 R AOXSr 8-amino-7-oxononanoate synthase M ala DASH L c + M h c + M pmcoa c )−−−−* M 8aonn c + M co2 c + M coa c 89 R APATr B-alanine-pyruvate aminotransferase M ala DASH B c + M pyr c )−−−−* M ala DASH L c + M msa c 90 R APRAUR 5-amino-6-(5-phosphoribosylamino)uracil M 5apru c + M h c + reductase M nadph c −→ M 5aprbu c + M nadp c 91 R ARABF arabinan complex formation (M tb) 12 M arab DASH D c+8 M mharab DASH D c+ 12 M tarab DASH D c −→ M arabinan c + 32 M h2o c o N¯ Id Name Reaction Equation SBO 92 R ARABI arabinose isomerase M arab DASH D c )−−−−* M rbl DASH D c 93 R ARACHTA transacylase M ACP c + M arachcoa c )−−−−* M arachACP c + M coa c 94 R ARAI L-arabinose isomerase M arab DASH L c )−−−−* M rbl DASH L c 95 R ARB Dabc L-arabinose transport via ABC system M arab DASH D e + M atp c + M h2o c −→ M adp c + M arab DASH D c + M h c + M pi c 96 R ARBabc L-arabinose transport via ABC system M arab DASH L e + M atp c + M h2o c −→ M adp c + M arab DASH L c +

rdcdby Produced M h c + M pi c 97 R ARBt2r L-arabinose transport via proton symport M arab DASH L e + M h e )−−−−* M arab DASH L c + M h c 98 R ARGDC arginine decarboxylase M arg DASH L c + M h c −→ M agm c + M co2 c SBML 99 R ARGDr arginine deiminase M arg DASH L c +

2 M h2o c )−−−−* M citr DASH L c + M nh4 c L A T −−* + E 100 R ARGSL argininosuccinate lyase M argsuc c )−− M arg DASH L c M fum c X 101 R ARGSS argininosuccinate synthase M asp DASH L c + M atp c + M citr DASH L c −→ M amp c + M argsuc c + M h c + M ppi c 102 R ARGt5r L-arginine transport via diffusion M arg DASH L e )−−−−* M arg DASH L c 103 R ARI arabinose ribose isomerase M arpp c )−−−−* M prpp c 104 R ASAD aspartate-semialdehyde dehydrogenase M aspsa c + M nadp c + M pi c )−−−−* M 4pasp c + M h c + M nadph c 105 R ASNN L-asparaginase M asn DASH L c + M h2o c −→ M asp DASH L c + M nh4 c 106 R ASNS1 asparagine synthase (glutamine-hydrolysing) M asp DASH L c+M atp c+M gln DASH L c+ M h2o c −→ M amp c + M asn DASH L c + 51 M glu DASH L c + M h c + M ppi c 52 o N¯ Id Name Reaction Equation SBO 107 R ASNt2r L-asparagine reversible transport via proton M asn DASH L e + symport M h e )−−−−* M asn DASH L c + M h c 108 R ASP1DC aspartate 1-decarboxylase M asp DASH L c + M h c −→ M ala DASH B c + M co2 c 109 R ASPCT aspartate carbamoyltransferase M asp DASH L c + M cbp c −→ M cbasp c + M h c + M pi c 110 R ASPK aspartate kinase M asp DASH L c + M atp c )−−−−* M 4pasp c + M adp c 111 R ASPO1 L-aspartate oxidase M asp DASH L c + M h2o c +

rdcdby Produced M o2 c −→ M h2o2 c + M nh4 c + M oaa c 112 R ASPO5 L-aspartate oxidase M asp DASH L c + M fum c −→ M h c + M iasp c + M succ c 113 R ASPTA aspartate transaminase M akg c+M asp DASH L c )−−−−* M glu DASH L c+ M oaa c SBML 114 R ASPt2r L-aspartate reversible transport via proton M asp DASH L e +

2 symport M h e )−−−−* M asp DASH L c + M h c L A T + −→ + E 115 R AST Arginine succinyltransferase M arg DASH L c M succoa c M coa c X M h c + M sucarg c 116 R ATPPRT ATP phosphoribosyltransferase M atp c + M prpp c −→ M ppi c + M prbatp c 117 R ATPS1 H+-exporting ATPase M atp c + M h2o c + M h c −→ M adp c + 2 M h e + M pi c 118 R ATPS4r ATP synthase (four protons for one ATP) M adp c + 4 M h e + M pi c )−−−−* M atp c + M h2o c + 3 M h c 119 R BACCL biotin-[acetyl-CoA-carboxylase] ligase M atp c + M btn c + M h c −→ M btamp c + M ppi c 120 R BALAt2r beta-alanine reversible transport via proton M ala DASH B e + symport M h e )−−−−* M ala DASH B c + M h c 121 R BDH (R)-3-Hydroxybutanoate:NAD+ oxidoreduc- M bhb c + M nad c )−−−−* M acac c + M h c + tase M nadh c o N¯ Id Name Reaction Equation SBO 122 R BETALDHx betaine-aldehyde dehydrogenase M betald c + M h2o c + M nad c −→ M glyb c + 2 M h c + M nadh c 123 R BMNMSHS conjugated mycothiol synthesis M bmn c + M msh c −→ M bmnmsh c + 2 M h c 124 R BMNt bimane transport (diffusion) M bmn c )−−−−* M bmn e 125 R BPNT 3’,5’-bisphosphate nucleotidase M h2o c + M pap c −→ M amp c + M pi c 126 R BTS2 biotin synthase (ala-L producing) M cys DASH L c + M dtbt c )−−−−* M ala DASH L c + M btn c + 2 M h c 127 R BTS3r biotin synthase M dtbt c + 2 M s c )−−−−* M btn c + M h2s c

rdcdby Produced 128 R CAATPS Ca ATPase M atp c + 2 M ca2 c + M h2o c −→ M adp c + 2 M ca2 e + M h e + M pi c 129 R CAT catalase 2 M h2o2 c −→ 2 M h2o c + M o2 c 130 R CAt4 calcium transport in/out via proton antiporter M ca2 c + M h e )−−−−* M ca2 e + M h c 131 R CBIAT Cobinamide adenyltransferase M atp c + M cbi c + M h c )−−−−* M adocbi c + SBML M pppi c

2 132 R CBLAT cob(I)alamin adenosyltransferase M atp c + M cbl1 c + M h c )−−−−* M adocbl c + L A T

E M pppi c X 133 R CBPS carbamoyl-phosphate synthase (glutamine- 2 M atp c + M gln DASH L c + M h2o c + hydrolysing) M hco3 c −→ 2 M adp c + M cbp c + M glu DASH L c + 2 M h c + M pi c 134 R CDAPPA160 CDP-Diacylglycerol pyrophostatase (n- M cdpdhdecg c + M h2o c −→ M cmp c + C16:0) 2 M h c + M pa160 c 135 R CDAPPA160190 CDP-Diacylglycerol pyrophostatase (C16:0, M cdpc16c19g c + M h2o c −→ M cmp c + C19:0) 2 M h c + M pa160190 c 136 R CDAPPA190 CDP-Diacylglycerol pyrophostatase (C19:0) M cdpc19c19g c + M h2o c −→ M cmp c + 2 M h c + M pa190190 c 137 R CDPMEK 4-(cytidine 5’-diphospho)-2-C-methyl-D- M 4c2me c + M atp c −→ M 2p4c2me c + erythritol kinase M adp c + M h c 53 54 o N¯ Id Name Reaction Equation SBO 138 R CDPPT160 CDP diacylglycerol inositon 3- M cdpdhdecg c + M inost c −→ M cmp c + phosphatidyltransferase M h c + M ptd1ino160 c 139 R CDPPT160190 CDP diacylglycerol inositon 3- M cdpc16c19g c + M inost c −→ M cmp c + phosphatidyltransferase M h c + M ptd1ino160190 c 140 R CHLabc choline transport via ABC system M atp c + M chol e + M h2o c −→ M adp c + M chol c + M h c + M pi c 141 R CHOLD choline dehydrogenase M chol c + M nad c −→ M betald c + M h c + M nadh c 142 R CHORM chorismate mutase M chor c −→ M pphn c

rdcdby Produced 143 R CHORS chorismate synthase M 3psme c −→ M chor c + M pi c 144 R CHRPL Chorismate pyruvate lyase M chor c −→ M 4hbz c + M pyr c 145 R CIGAMS cys-1D-myo-inositol 2-deoxy-D- M atp c + M cys DASH L c + glucopyranoside synthase M igam c −→ M amp c + M cigam c + 2 M h c + M ppi c SBML 146 R CITL Citrate lyase M cit c −→ M ac c + M oaa c

2 147 R CITLr Citrate lyase (reversible) M cit c )−−−−* M ac c + M oaa c L A T + + −→ + E 148 R CITabc citrate transport via ABC system M atp c M cit e M h2o c M adp c X M cit c + M h c + M pi c 149 R CLPNS160190 cardiolipin synthase (C16:0, C19:0) tubercu- 2 M pg160190 c )−−−−* M clpn160190 c + M glyc c losis 150 R CMCBTFL carboxymycobactin Fe3 loading M cmcbtt c + M fe3 e −→ M fcmcbtt c 151 R CMCBTFU carboxymycobactin Fe3 unloading M fcmcbtt c −→ M cmcbtt c + M fe3 c 152 R CMLDC 4-carboxymuconolactone decarboxylase M 2c25dho c −→ M 5odhf2a c+M co2 c+M h c 153 R CO2t CO2 transporter via diffusion M co2 e )−−−−* M co2 c 154 R COAt CoA transporter M coa e )−−−−* M coa c 155 R COBALTt5 cobalt transport in/out via permease (no H+) M cobalt2 c )−−−−* M cobalt2 e 156 R COCHL cobaltochelatase M atp c + M cobalt2 c + M h2o c + M hgbam c −→ M adp c + M co2dam c + 2 M h c + M pi c o N¯ Id Name Reaction Equation SBO 157 R CODH2r carbon monoxide dehydrogenase / acetyl- M co c + 2 M fdox c + M h2o c )−−−−* M co2 c + CoA synthase 2 2 M fdred c + 2 M h c 158 R CODH3 carbon monoxide dehydrogenase / acetyl- M adfdOX c + 2 M co c + CoA synthase 2 2 M h2o c −→ M adfdRD c+2 M co2 c+2 M h c 159 R COt CO transporter via diffusion M co c )−−−−* M co e 160 R CPC2MT precorrin-2 C20-methyltransferase M amet c + M copre2 c −→ M ahcys c + M copre3 c + M h c 161 R CPC3MT precorrin-3B C17-methyltransferase M amet c + M copre3 c −→ M ahcys c + M copre4 c

rdcdby Produced 162 R CPC4MT precorrin-4 C11-methyltransferase M amet c + M copre4 c −→ M ahcys c + M copre5 c + M h c 163 R CPC6MT precorrin-6Y C5,15-methyltransferase (de- 2 M amet c + M codhpre6 c −→ 2 M ahcys c + carboxylating) M co2 c + M copre8 c + M h c 164 R CPC6R precorrin-6A reductase M copre6 c + M h c + SBML M nadph c −→ M codhpre6 c + M nadp c

2 165 R CPC8MM precorrin-8X methylmutase M copre8 c )−−−−* M cobya c L A T + + −→ + E 166 R CPPPGO coproporphyrinogen oxidase (O2 required) M cpppg3 c 2 M h c M o2 c 2 M co2 c X 2 M h2o c + M pppg9 c 167 R CRNabc L-carnitine transport via ABC system M atp c + M crn e + M h2o c −→ M adp c + M crn c + M h c + M pi c 168 R CS citrate synthase M accoa c + M h2o c + M oaa c −→ M cit c + M coa c + M h c 169 R CTPS1 CTP synthase (NH3) M atp c + M nh4 c + M utp c −→ M adp c + M ctp c + 2 M h c + M pi c 170 R CTPS2 CTP synthase (glutamine) M atp c + M gln DASH L c + M h2o c + M utp c −→ M adp c + M ctp c + M glu DASH L c + 2 M h c + M pi c 171 R CYANST Cyanide sulfurtransferase M cyan c + M tsul c −→ M h c + M so3 c + 55 M tcynt c 56 o N¯ Id Name Reaction Equation SBO 172 R CYO1a cytochrome-c reductase (ubiquinol: 2 pro- 2 M ﬁcytc c + 2 M h c + tons) M qh2 c −→ 2 M focytc c + 2 M h e + M q c 173 R CYO1b cytochrome-c oxidase (2 protons) 2 M focytc c + 0 ·5 M o2 c −→ 2 M ﬁcytc c + M h2o c 174 R CYRDAAT cob(I)yrinic acid a,c-diamide adenosyltrans- M atp c + M co1dam c + ferase M h c −→ M adcobdam c + M pppi c 175 R CYRDAR cob(II)yrinic acid a,c-diamide reductase 2 M co2dam c + M nadh c −→ 2 M co1dam c + M h c + M nad c 176 R CYSS cysteine synthase M acser c + M h2s c −→ M ac c +

rdcdby Produced M cys DASH L c + M h c 177 R CYSTGL cystathionine g-lyase M cyst DASH L c + M h2o c −→ M 2obut c + M cys DASH L c + M nh4 c 178 R CYSTL cystathionine b-lyase M cyst DASH L c + M h2o c −→ M hcys DASH L c + M nh4 c + SBML M pyr c

2 179 R CYSTS cystathionine beta-synthase M hcys DASH L c + L A T −→ + E M ser DASH L c M cyst DASH L c X M h2o c 180 R CYTBD cytochrome oxidase bd (ubiquinol-8: 2 pro- 2 M h c + 0 ·5 M o2 c + M q8h2 c −→ M h2o c + tons) 2 M h e + M q8 c 181 R CYTBD2 cytochrome oxidase bd (menaquinol-8: 2 pro- 2 M h c + M mql8 c + 0 ·5 M o2 c −→ M h2o c + tons) 2 M h e + M mqn8 c 182 R CYTD cytidine deaminase M cytd c + M h2o c + M h c −→ M nh4 c + M uri c 183 R CYTDK2 cytidine kinase (GTP) M cytd c + M gtp c −→ M cmp c + M gdp c + M h c 184 R CYTDt2r cytidine transport in via proton symport, re- M cytd e + M h e )−−−−* M cytd c + M h c versible 185 R CYTK1 cytidylate kinase (CMP) M atp c + M cmp c )−−−−* M adp c + M cdp c o N¯ Id Name Reaction Equation SBO 186 R CYTK2 cytidylate kinase (dCMP) M atp c + M dcmp c )−−−−* M adp c + M dcdp c 187 R Clt chlorideion transport out via diffusion M cl e )−−−−* M cl c 188 R Cuabc Copper transport via ABC system M atp c + M cu2 e + M h2o c −→ M adp c + M cu2 c + M h c + M pi c 189 R Cut1 Copper export via ATPase M atp c + M cu2 c + M h2o c −→ M adp c + M cu2 e + M h c + M pi c 190 R DADA Deoxyadenosine deaminase M dad DASH 2 c + M h2o c + M h c −→ M din c + M nh4 c 191 R DADK deoxyadenylate kinase M atp c + M damp c )−−−−* M adp c + M dadp c

rdcdby Produced 192 R DAGK160 diacylglycerol kinase (n-C16:0) M 12dgr160 c + M atp c −→ M adp c + M h c + M pa160 c 193 R DALAOX D-Alanine Oxidase M ala DASH D c + M h2o c + M o2 c −→ M h2o2 c + M nh4 c + M pyr c 194 R DALAt2r D-alanine transport via proton symport M ala DASH D e + SBML M h e )−−−−* M ala DASH D c + M h c

2 195 R DAPDC diaminopimelate decarboxylase M 26dap DASH M c + M h c −→ M co2 c + L A T

E M lys DASH L c X 196 R DAPE diaminopimelate epimerase M 26dap DASH LL c )−−−−* M 26dap DASH M c 197 R DASYN160 CDP-diacylglycerol synthetase (n-C16:0) M ctp c + M h c + M pa160 c −→ M cdpdhdecg c + M ppi c 198 R DASYN160190 CDP-diacylglycerol synthetase (C16:0, M ctp c + M h c + C19:0) M pa160190 c −→ M cdpc16c19g c + M ppi c 199 R DASYN190190 CDP-diacylglycerol synthetase (C19:0, M ctp c + M h c + C19:0) M pa190190 c −→ M cdpc19c19g c + M ppi c 200 R DB4PS 3,4-Dihydroxy-2-butanone-4-phosphate syn- M ru5p DASH D c −→ M db4p c + M for c + thase M h c 201 R DBTSr dethiobiotin synthase M atp c + M co2 c + M dann c )−−−−* M adp c + M dtbt c + 3 M h c + M pi c 57 58 o N¯ Id Name Reaction Equation SBO 202 R DCPDP decaprenyl-diphosphatase M decdp tb c + M h2o c −→ M decd tb c + M h c + M pi c 203 R DCPDPP decaprenylphosphoryl ribose phosphate de- M decdpr tb c + M h2o c −→ M decdr tb c + phosphatase M pi c 204 R DCPDPP2 decaprenylphosphoryl arabinose phosphate M decdpa tb c + M h2o c −→ M decda tb c + dephosphatase M pi c 205 R DCPDPS Decaprenyl diphosphate synthase M frdp c + 7 M ipdp c −→ M decdp tb c + 7 M ppi c 206 R DCPE decaprenylphosphoryl ribose, arabinofura- M decdr tb c )−−−−* M decda tb c

rdcdby Produced nose isomerization 207 R DCPT phosphoribose transferase (undecaprenyl M decd tb c + M prpp c −→ M decdpr tb c + phosphate) M ppi c 208 R DCPT2 phosphoribose transferase (undecaprenyl M arpp c + M decd tb c −→ M decdpa tb c + phosphate) M ppi c SBML 209 R DCTPD dCTP deaminase M dctp c + M h2o c + M h c −→ M dutp c +

2 M nh4 c L A T + + −→ + E 210 R DCTPD2 dCTP deaminase M ctp c M h2o c M h c M nh4 c X M utp c 211 R DCYTD deoxycytidine deaminase M dcyt c + M h2o c + M h c −→ M duri c + M nh4 c 212 R DDPA 3-deoxy-D-arabino-heptulosonate 7- M e4p c + M h2o c + M pep c −→ M 2dda7p c + phosphate synthetase M pi c 213 R DESAT16 Palmitoyl-CoA desaturase (n-C16:0CoA -> M h c + M nadph c + M o2 c + n-C16:1CoA) M pmtcoa c −→ 2 M h2o c + M hdcoa c + M nadp c 214 R DESAT18 stearoyl-CoA desaturase (n-C18:0CoA -> n- M h c + M nadph c + M o2 c + C18:1CoA) M stcoa c −→ 2 M h2o c + M nadp c + M odecoa c o N¯ Id Name Reaction Equation SBO 215 R DGC3D 2-deoxy-D-gluconate 3-dehydrogenase M 2dglcn c + M nad c −→ M 3ddgc c + M h c + M nadh c 216 R DGK1 deoxyguanylate kinase (dGMP:ATP) M atp c + M dgmp c )−−−−* M adp c + M dgdp c 217 R DHAD1 dihydroxy-acid dehydratase (2,3-dihydroxy- M 23dhmb c −→ M 3mob c + M h2o c 3-methylbutanoate) 218 R DHAD2 Dihydroxy-acid dehydratase (2,3-dihydroxy- M 23dhmp c −→ M 3mop c + M h2o c 3-methylpentanoate) 219 R DHDPRy dihydrodipicolinate reductase (NADPH) M 23dhdp c + M h c + M nadph c −→ M nadp c + M thdp c

rdcdby Produced 220 R DHDPS dihydrodipicolinate synthase M aspsa c + M pyr c −→ M 23dhdp c + 2 M h2o c + M h c 221 R DHFR dihydrofolate reductase M dhf c + M h c + M nadph c )−−−−* M nadp c + M thf c 222 R DHFS dihydrofolate synthase M atp c + M dhpt c + SBML M glu DASH L c −→ M adp c + M dhf c +

2 M h c + M pi c L A T + −→ + E 223 R DHNAOT 1,4-dihydroxy-2-naphthoate octaprenyltrans- M dhna c M octdp c M 2dmmq8 c X ferase M co2 c + M h c + M ppi c 224 R DHNAOT2 1,4-dihydroxy-2-naphthoate octaprenyltrans- M dhna c + M octdp c −→ M 2dmmq6 c + ferase M co2 c + M h c + M ppi c 225 R DHNPA dihydroneopterin aldolase M dhnpt c −→ M 2ahhmp c + M gcald c + M h c 226 R DHNPA2 dihydroneopterin aldolase M dhnpt c −→ M 6hmhpt c + M gcald c 227 R DHORD2 dihydoorotic acid dehydrogenase (quinone8) M dhor DASH S c + M q8 c −→ M orot c + M q8h2 c 228 R DHORD3 dihydroorotic acid dehydrogenase M dhor DASH S c + M mqn6 c )−−−−* M mql6 c + (menaquinone 6) M orot c 229 R DHORD5 dihydroorotic acid (menaquinone-8) M dhor DASH S c + M mqn8 c −→ M mql8 c + M orot c 59 60 o N¯ Id Name Reaction Equation SBO 230 R DHORTS dihydroorotase M dhor DASH S c + M h2o c )−−−−* M cbasp c + M h c 231 R DHPPDA diaminohydroxyphosphoribosylaminopyrimidineM 25dhpp c + M h2o c + M h c −→ M 5apru c + deaminase M nh4 c 232 R DHPPDA2 diaminohydroxyphosphoribosylaminopryrimidineM 25drapp c + M h2o c + M h c −→ M 5apru c + deaminase (25drapp) M nh4 c 233 R DHPS2 dihydropteroate synthase M 4abz c + M 6hmhptpp c −→ M dhpt c + M ppi c 234 R DHQD 3-dehydroquinate dehydratase M 3dhq c )−−−−* M 3dhsk c + M h2o c

rdcdby Produced 235 R DHQS 3-dehydroquinate synthase M 2dda7p c −→ M 3dhq c + M pi c 236 R DMATT dimethylallyltranstransferase M dmpp c + M ipdp c −→ M grdp c + M ppi c 237 R DMPPS 1-hydroxy-2-methyl-2-(E)-butenyl 4- M h2mb4p c + M h c + diphosphate reductase (dmpp) M nadh c −→ M dmpp c + M h2o c + M nad c 238 R DM atp c atp demand M atp c −→ /0 SBML 239 R DNMPPA Dihydroneopterin monophosphate dephos- M dhpmp c + M h2o c −→ M dhnpt c + M pi c

2 phorylase L A T + −→ + + E 240 R DNTPPA Dihydroneopterin triphosphate pyrophos- M ahdt c M h2o c M dhpmp c M h c X phatase M ppi c 241 R DPCOAK dephospho-CoA kinase M atp c + M dpcoa c −→ M adp c + M coa c + M h c 242 R DPPS decaprenyl synthase M frdp c + 7 M ipdp c −→ M decdp c + 7 M ppi c 243 R DPR 2-dehydropantoate 2-reductase M 2dhp c + M h c + M nadph c −→ M nadp c + M pant DASH R c 244 R DRPA deoxyribose-phosphate aldolase M 2dr5p c −→ M acald c + M g3p c 245 R DSERt2r D-serine transport via proton symport M h e + M ser DASH D e )−−−−* M h c + M ser DASH D c 246 R DTMPK dTMP kinase M atp c + M dtmp c )−−−−* M adp c + M dtdp c 247 R DURIK1 deoxyuridine kinase (ATP:Deoxyuridine) M atp c + M duri c −→ M adp c + M dump c + M h c o N¯ Id Name Reaction Equation SBO 248 R DURIPP deoxyuridine phosphorylase M duri c + M pi c )−−−−* M 2dr1p c + M ura c 249 R DUTPDP dUTP diphosphatase M dutp c + M h2o c −→ M dump c + M h c + M ppi c 250 R DXPRIi 1-deoxy-D-xylulose reductoisomerase M dxyl5p c + M h c + M nadph c −→ M 2me4p c + M nadp c 251 R DXPS 1-deoxy-D-xylulose 5-phosphate synthase M g3p c + M h c + M pyr c −→ M co2 c + M dxyl5p c 252 R E4PD Erythrose 4-phosphate dehydrogenase M e4p c + M h2o c + M nad c )−−−−* M 4per c + 2 M h c + M nadh c

rdcdby Produced 253 R ECHH 0 Ech hydrogenase (no electron transport) 2 M fdox c + M h2 c )−−−−* 2 M fdred c + 2 M h c 254 R ENO enolase M 2pg c )−−−−* M h2o c + M pep c 255 R ENTCS enterochelin synthase 3 M 23dhba c + 3 M seramp c −→ 6 M amp c + M enter c + 9 M h c 256 R ETHAt ethanolamine transport via diffusion (extra- M etha e )−−−−* M etha c SBML cellular)

2 257 R EX acysbmn e acetyl-cystine-bimane exchange M acysbmn e −→ /0 L A T −→ E 258 R EX ala DASH- beta-Alanine exchange M ala DASH B e /0 X B e 259 R EX ala DASH- D-Alanine exchange M ala DASH D e −→ /0 D e 260 R EX ala DASH- L-Alanine exchange M ala DASH L e −→ /0 L e 261 R EX arab DASH- D-Arabinose exchange M arab DASH D e −→ /0 D e 262 R EX arab DASH- L-Arabinose exchange M arab DASH L e −→ /0 L e 263 R EX arg DASH- L-Arginine exchange M arg DASH L e −→ /0 L e 61 62 o N¯ Id Name Reaction Equation SBO 264 R EX asn DASH- L-Asparagine exchange M asn DASH L e −→ /0 L e 265 R EX asp DASH- L-Aspartate exchange M asp DASH L e −→ /0 L e 266 R EX atp e ATP exchange M atp e −→ /0 267 R EX bmn e bimane exchange M bmn e −→ /0 268 R EX ca2 e Calcium exchange M ca2 e )−−−−* /0 269 R EX chol e Choline exchange M chol e −→ /0 270 R EX cit e Citrate exchange M cit e )−−−−* /0

rdcdby Produced 271 R EX cl e Chloride exchange M cl e )−−−−* /0 272 R EX co2 e CO2 exchange M co2 e −→ /0 273 R EX co e Carbon monoxide exchange M co e −→ /0 274 R EX coa e Coenzyme A exchange M coa e −→ /0 275 R EX cobalt2 e Co2+ exchange M cobalt2 e −→ /0 SBML 276 R EX crn e L-Carnitine exchange M crn e −→ /0

2 277 R EX cu2 e Cu2+ exchange M cu2 e )−−−−* /0 L A T −→ E 278 R EX cytd e Cytidine exchange M cytd e /0 X 279 R EX etha e Ethanolamine exchange M etha e −→ /0 280 R EX fe2 e Fe2+ exchange M fe2 e −→ /0 281 R EX fe3 e Fe3+ exchange M fe3 e )−−−−* /0 282 R EX fum e Fumarate exchange M fum e −→ /0 283 R EX gal e D-Galactose exchange M gal e −→ /0 284 R EX glc DASH- D-Glucose exchange M glc DASH D e )−−−−* /0 D e 285 R EX glu DASH- L-Glutamate exchange M glu DASH L e )−−−−* /0 L e 286 R EX gly e Glycine exchange M gly e −→ /0 287 R EX glyb e Glycine betaine exchange M glyb e −→ /0 288 R EX glyc3p e Glycerol 3-phosphate exchange M glyc3p e −→ /0 o N¯ Id Name Reaction Equation SBO 289 R EX glyc e Glycerol exchange M glyc e )−−−−* /0 290 R EX gthrd e Reduced glutathione exchange M gthrd e −→ /0 291 R EX h2 e H2 exchange M h2 e −→ /0 292 R EX h2co3 e carbonic acid exchange M h2co3 e )−−−−* /0 293 R EX h2o e H2O exchange M h2o e )−−−−* /0 294 R EX h2s e Hydrogen sulﬁde exchange M h2s e −→ /0 295 R EX h e H+ exchange M h e )−−−−* /0 296 R EX hdca e Hexadecanoate (n-C16:0) exchange M hdca e −→ /0 297 R EX his DASH- L-Histidine exchange M his DASH L e −→ /0

rdcdby Produced L e 298 R EX id3acald e Indole-3-acetaldehyde exchange M id3acald e −→ /0 299 R EX ile DASH- L-Isoleucine exchange M ile DASH L e −→ /0 L e 300 R EX k e K+ exchange M k e )−−−−* /0 SBML 301 R EX lac DASH- L-Lactate exchange M lac DASH L e −→ /0

2 L e L A T −→ E 302 R EX lcts e Lactose exchange M lcts e /0 X 303 R EX leu DASH- L-Leucine exchange M leu DASH L e −→ /0 L e 304 R EX lys DASH- L-Lysine exchange M lys DASH L e −→ /0 L e 305 R EX mal DASH- L-Malate exchange M mal DASH L e −→ /0 L e 306 R EX malt e Maltose exchange M malt e −→ /0 307 R EX malthp e Maltoheptaose exchange M malthp e −→ /0 308 R EX meoh e methanol exchange M meoh e −→ /0 309 R EX met DASH- L-Methionine exchange M met DASH L e −→ /0 L e 63 310 R EX mg2 e Mg exchange M mg2 e −→ /0 64 o N¯ Id Name Reaction Equation SBO 311 R EX na1 e Sodium exchange M na1 e )−−−−* /0 312 R EX nh4 e Ammonia exchange M nh4 e )−−−−* /0 313 R EX no2 e Nitrite exchange M no2 e −→ /0 314 R EX no3 e Nitrate exchange M no3 e −→ /0 315 R EX no e Nitric oxide exchange M no e −→ /0 316 R EX o2 e O2 exchange M o2 e )−−−−* /0 317 R EX ocdca e octadecanoate (n-C18:0) exchange M ocdca e −→ /0 318 R EX orn e Ornithine exchange M orn e −→ /0 319 R EX pac e Phenylacetic acid exchange M pac e −→ /0

rdcdby Produced 320 R EX pdima e phthiocerol dimycocerosate A (Mtb) ex- M pdima e −→ /0 change 321 R EX phdca e phenol palmitic acid exchange M phdca e −→ /0 322 R EX phe DASH- L-Phenylalanine exchange M phe DASH L e −→ /0 L e SBML 323 R EX pi e Phosphate exchange M pi e )−−−−* /0

2 324 R EX ppa e Propionate exchange M ppa e −→ /0 L A T −→ E 325 R EX ppdima e phenol phthiocerol dimycocerosate (Mtb) ex- M ppdima e /0 X change 326 R EX pro DASH- L-Proline exchange M pro DASH L e −→ /0 L e 327 R EX pyr e Pyruvate exchange M pyr e −→ /0 328 R EX rib DASH- D-Ribose exchange M rib DASH D e −→ /0 D e 329 R EX ser DASH- D-Serine exchange M ser DASH D e −→ /0 D e 330 R EX ser DASH- L-Serine exchange M ser DASH L e −→ /0 L e 331 R EX skm e Shikimate exchange M skm e −→ /0 332 R EX so4 e Sulfate exchange M so4 e )−−−−* /0 o N¯ Id Name Reaction Equation SBO 333 R EX succ e Succinate exchange M succ e −→ /0 334 R EX tartr- L-tartrate exchange M tartr DASH L e −→ /0 DASH L e 335 R EX thr DASH- L-Threonine exchange M thr DASH L e −→ /0 L e 336 R EX tre e Trehalose exchange M tre e −→ /0 337 R EX trp DASH- L-Tryptophan exchange M trp DASH L e −→ /0 L e 338 R EX tsul e Thiosulfate exchange M tsul e −→ /0

rdcdby Produced 339 R EX ttdca e tetradecanoate (n-C14:0) exchange M ttdca e −→ /0 340 R EX tyr DASH- L-Tyrosine exchange M tyr DASH L e −→ /0 L e 341 R EX val DASH- L-Valine exchange M val DASH L e −→ /0 L e SBML 342 R EX xyl DASH- D-Xylose exchange M xyl DASH D e −→ /0

2 D e L A T + −→ + + E 343 R FACOAE140 fatty-acid-CoA thioesterase (tetradecanoate) M h2o c M tdcoa c M coa c M h c X M ttdca c 344 R FACOAE160 fatty-acid-CoA thioesterase (hexadecanoate) M h2o c + M pmtcoa c −→ M coa c + M h c + M hdca c 345 R FACOAE180 fatty-acid-CoA thioesterase (octadecanoate) M h2o c + M stcoa c −→ M coa c + M h c + M ocdca c 346 R FACOAL140 fatty-acid–CoA ligase (tetradecanoate) M atp c + M coa c + M ttdca c )−−−−* M amp c + M ppi c + M tdcoa c 347 R FACOAL160 fatty-acid–CoA ligase (hexadecanoate) M atp c + M coa c + M hdca c )−−−−* M amp c + M pmtcoa c + M ppi c 348 R FACOAL161 fatty-acid–CoA ligase (hexadecenoate) M atp c + M coa c + M hdcea c )−−−−* M amp c + M hdcoa c + M ppi c 65 66 o N¯ Id Name Reaction Equation SBO 349 R FACOAL180 fatty-acid–CoA ligase (octadecanoate) M atp c + M coa c + M ocdca c )−−−−* M amp c + M ppi c + M stcoa c 350 R FACOAL181 fatty-acid–CoA ligase (octadecenoate) M atp c + M coa c + M ocdcea c )−−−−* M amp c + M odecoa c + M ppi c 351 R FACOAL200 fatty-acid–CoA ligase M arach c + M atp c + M coa c )−−−−* M amp c + M arachcoa c + M ppi c 352 R FACOAL80 fatty-acid–CoA ligase (octanoate) M atp c + M coa c + M octa c )−−−−* M amp c + M occoa c + M ppi c 353 R FACOALPHDCA fatty-acid–CoA ligase M atp c + M coa c + M phdca c )−−−−* M amp c +

rdcdby Produced M phdcacoa c + M ppi c 354 R FACOALPREPH fatty-acid–CoA ligase (phthiocerol precursor) M atp c + M coa c + M prephth c )−−−−* M amp c + M ppi c + M prephthcoa c 355 R FAH4 Fatty acid hydroxylase M h c + M nadph c + M o2 c + M omtta c −→ M h2o c+M homtta c+M nadp c SBML 356 R FAMPL1 Fatty Acid Ligase AMP (mycolic acid) M amp c + M h c +

2 M meroacidcyc2ACP c −→ M ACP c + L A T

E M meroacidcyc2AMP c X 357 R FAMPL2 Fatty Acid Ligase AMP (mycolic acid) M amp c + M h c + M mmeroacidcyc2ACP c −→ M ACP c + M mmeroacidcyc2AMP c 358 R FAMPL3 Fatty Acid Ligase AMP (mycolic acid) M amp c + M h c + M kmeroacidcyc2ACP c −→ M ACP c + M kmeroacidcyc2AMP c 359 R FAMPL4 Fatty Acid Ligase AMP (mycolic acid) M amp c + M h c + M mmmeroacidcyc1ACP c −→ M ACP c + M mmmeroacidcyc1AMP c 360 R FAMPL5 Fatty Acid Ligase AMP (mycolic acid) M amp c + M h c + M mkmeroacidcyc1ACP c −→ M ACP c + M mkmeroacidcyc1AMP c o N¯ Id Name Reaction Equation SBO 361 R FAO1 Fatty acid oxidation (tetradecanoate) M atp c + 7 M coa c + 6 M fad c + 6 M h2o c + 6 M nad c + M ttdca c −→ 7 M accoa c + M amp c + 6 M fadh2 c + 6 M h c + 6 M nadh c + M ppi c 362 R FAO10 Fatty acid oxidation (octadecenoate) M atp c + 9 M coa c + 7 M fad c + 8 M h2o c + 8 M nad c + M ocdcea c −→ 9 M accoa c + M amp c + 7 M fadh2 c + 8 M h c + 8 M nadh c + M ppi c 363 R FAO11 Fatty acid oxidation (n-C16:1) M atp c + 8 M coa c + 6 M fad c + 7 M h2o c +

rdcdby Produced M hdcea c + 7 M nad c −→ 8 M accoa c + M amp c + 6 M fadh2 c + 7 M h c + 7 M nadh c + M ppi c 364 R FAO2 Fatty acid oxidation (n-C16:0) M atp c + 8 M coa c + 7 M fad c + 7 M h2o c + M hdca c + 7 M nad c −→ 8 M accoa c + SBML M amp c + 7 M fadh2 c + 7 M h c + 7 M nadh c +

2 M ppi c L A T + + + + E 365 R FAO3 Fatty acid oxidation (octadecanoate) M atp c 9 M coa c 8 M fad c 8 M h2o c X 8 M nad c + M ocdca c −→ 9 M accoa c + M amp c + 8 M fadh2 c + 8 M h c + 8 M nadh c + M ppi c 366 R FAS100 fatty acid synthase (n-C10:0) 3 M h c + M malcoa c + 2 M nadph c + M octa c −→ M co2 c + M coa c + M dca c + M h2o c + 2 M nadp c 367 R FAS120 fatty acid synthase (n-C12:0) M dca c + 3 M h c + M malcoa c + 2 M nadph c −→ M co2 c + M coa c + M ddca c + M h2o c + 2 M nadp c 368 R FAS140 fatty acid synthase (n-C14:0) M ddca c + 3 M h c + M malcoa c + 2 M nadph c −→ M co2 c + M coa c + M h2o c + 67 2 M nadp c + M ttdca c 68 o N¯ Id Name Reaction Equation SBO 369 R FAS160 fatty acid synthase (n-C16:0) 3 M h c + M malcoa c + 2 M nadph c + M ttdca c −→ M co2 c + M coa c + M h2o c + M hdca c + 2 M nadp c 370 R FAS161 fatty acid synthase (n-C16:1) 4 M h c + M malcoa c + 3 M nadph c + M o2 c + M ttdca c −→ M co2 c + M coa c + 3 M h2o c + M hdcea c + 3 M nadp c 371 R FAS180 fatty acid synthase (n-C18:0) 3 M h c + M hdca c + M malcoa c + 2 M nadph c −→ M co2 c + M coa c + M h2o c + 2 M nadp c + M ocdca c

rdcdby Produced 372 R FAS181 fatty acid synthase (n-C18:1) 4 M h c + M hdca c + M malcoa c + 3 M nadph c + M o2 c −→ M co2 c + M coa c + 3 M h2o c + 3 M nadp c + M ocdcea c 373 R FAS200 fatty acid synthase (n-C20:0) 3 M h c + M malcoa c + 2 M nadph c + M ocdca c −→ M arach c + M co2 c + M coa c + SBML M h2o c + 2 M nadp c

2 374 R FAS240 L fatty acid synthase (n-C24:0), lumped reac- 9 M h c + 3 M malcoa c + 6 M nadph c + L A T −→ + + E tion M ocdca c 3 M co2 c 3 M coa c X 3 M h2o c + 6 M nadp c + M ttc c 375 R FAS260 fatty acid synthase (n-C26:0) 3 M h c + M malcoa c + 2 M nadph c + M ttc c −→ M co2 c + M coa c + M h2o c + M hexc c + 2 M nadp c 376 R FAS80 L fatty acid synthase (n-C8:0), lumped reaction M accoa c + 8 M h c + 3 M malcoa c + 6 M nadph c −→ 3 M co2 c + 4 M coa c + 2 M h2o c + 6 M nadp c + M octa c 377 R FASPHDCA fatty-acyl-ACP synthase (phdca) M 4hbzACP c + 24 M h c + 8 M malACP c + 16 M nadph c −→ 8 M ACP c + 8 M co2 c + 8 M h2o c + 16 M nadp c + M phdcaACP c o N¯ Id Name Reaction Equation SBO 378 R FASm1601 fatty acid synthase - methyl octadecanoic acid 3 M h c + M hdca c + M mmcoa DASH S c + 2 M nadph c −→ M co2 c + M coa c + M h2o c + M m1ocdca c + 2 M nadp c 379 R FASm180 fatty acid synthase - tuberculostearic acid 15 M h c + 4 M malcoa c + M mmcoa DASH S c + 10 M nadph c + M octa c −→ 5 M co2 c + 5 M coa c + 5 M h2o c + M mocdca c + 10 M nadp c 380 R FASm1801 fatty acid synthase - dimethyl arachic acid 3 M h c+M m1ocdca c+M mmcoa DASH S c+ 2 M nadph c −→ M co2 c + M coa c +

rdcdby Produced M dmarach c + M h2o c + 2 M nadp c 381 R FASm2001 fatty acid synthase - tri-methyl behenic acid M dmarach c + 3 M h c + M mmcoa DASH S c + 2 M nadph c −→ M co2 c + M coa c + M h2o c + 2 M nadp c + M tmbhn c 382 R FASm2002 fatty acid synthase - methyl-arachidic acid 3 M h c + M mmcoa DASH S c + 2 M nadph c + SBML M ocdca c −→ M co2 c + M coa c + M h2o c +

2 M marach c + 2 M nadp c L A T + + + E 383 R FASm220 fatty acid synthase - methyl-behenic acid M arach c 3 M h c M mmcoa DASH S c X 2 M nadph c −→ M co2 c + M coa c + M h2o c + M mbhn c + 2 M nadp c 384 R FASm2201 fatty acid synthase - tri-methyl lignoceric acid 3 M h c + M mmcoa DASH S c + 2 M nadph c + M tmbhn c −→ M co2 c + M coa c + M h2o c + 2 M nadp c + M tamlgnc c 385 R FASm2202 fatty acid synthase - di-methyl-behenic acid 3 M h c + M marach c + M mmcoa DASH S c + 2 M nadph c −→ M co2 c + M coa c + M dmbhn c + M h2o c + 2 M nadp c 386 R FASm240 fatty acid synthase - di-methyl lignoceric acid 3 M h c + M mbhn c + M mmcoa DASH S c + 2 M nadph c −→ M co2 c + M coa c + M dmlgnc c + M h2o c + 2 M nadp c 69 70 o N¯ Id Name Reaction Equation SBO 387 R FASm2401 fatty acid synthase - penta-methyl hexa- 3 M h c + M mmcoa DASH S c + 2 M nadph c + cosanoic acid M tamlgnc c −→ M co2 c + M coa c + M h2o c + 2 M nadp c + M pmhexc c 388 R FASm2402 fatty acid synthase - tri-methyl-lignoceric M dmbhn c + 3 M h c + M mmcoa DASH S c + acid 2 M nadph c −→ M co2 c + M coa c + M h2o c + 2 M nadp c + M tmlgnc c 389 R FASm260 fatty acid synthase - tri-methyl cerotic acid M dmlgnc c + 3 M h c + M mmcoa DASH S c + 2 M nadph c −→ M co2 c + M coa c + M h2o c + 2 M nadp c + M tmhexc c

rdcdby Produced 390 R FASm2601 fatty acid synthase - hexa-methyl octa- 3 M h c + M mmcoa DASH S c + 2 M nadph c + cosanoic acid M pmhexc c −→ M co2 c + M coa c + M h2o c + M hmocta c + 2 M nadp c 391 R FASm2602 fatty acid synthase - tetra-methyl hexa- 3 M h c + M mmcoa DASH S c + 2 M nadph c + cosanoic acid M tmlgnc c −→ M co2 c + M coa c + M h2o c + SBML 2 M nadp c + M tamhexc c

2 392 R FASm280 fatty acid synthase - tetra-methyl octa- 3 M h c + M mmcoa DASH S c + 2 M nadph c + L A T −→ + + + E cosanoic acid M tmhexc c M co2 c M coa c M h2o c X 2 M nadp c + M tamocta c 393 R FASm2801 fatty acid synthase - hepta-methyl triacon- 3 M h c + M hmocta c + M mmcoa DASH S c + tanoic acid 2 M nadph c −→ M co2 c + M coa c + M h2o c + M hpmtria c + 2 M nadp c 394 R FASm2802 fatty acid synthase - penta-methyl octa- 3 M h c + M mmcoa DASH S c + 2 M nadph c + cosanoic acid M tamhexc c −→ M co2 c+M coa c+M h2o c+ 2 M nadp c + M pmocta c 395 R FASm300 fatty acid synthase - hexa-methyl triacon- 3 M h c + M mmcoa DASH S c + 2 M nadph c + tanoic acid M pmocta c −→ M co2 c + M coa c + M h2o c + M hmtria c + 2 M nadp c o N¯ Id Name Reaction Equation SBO 396 R FASm3001 fatty acid synthase - octa-methyl dotriacon- 3 M h c + M hpmtria c + M mmcoa DASH S c + tanoic acid 2 M nadph c −→ M co2 c + M coa c + M h2o c + 2 M nadp c + M omdtria c 397 R FASm320 fatty acid synthase - hepta-methyl dotriacon- 3 M h c + M hmtria c + M mmcoa DASH S c + tanoic acid 2 M nadph c −→ M co2 c + M coa c + M h2o c + M hpmdtria c + 2 M nadp c 398 R FASm340 fatty acid synthase - octa-methyl tetraconta- 3 M h c+M hpmdtria c+M mmcoa DASH S c+ tricosanoic acid 2 M nadph c −→ M co2 c + M coa c + M h2o c + 2 M nadp c + M omtta c

rdcdby Produced 399 R FBA fructose-bisphosphate aldolase M fdp c )−−−−* M dhap c + M g3p c 400 R FBP fructose-bisphosphatase M fdp c + M h2o c −→ M f6p c + M pi c 401 R FCLPA L-fuculose 1-phosphate aldolase M fc1p c )−−−−* M dhap c + M lald DASH L c 402 R FCLT Ferrochelatase M fe2 c + M ppp9 c −→ 2 M h c + M pheme c 403 R FCLT2 Ferrochelatase M fmcbtt c + M ppp9 c −→ 2 M h c + SBML M mcbtt c + M pheme c

2 404 R FCOAH2 formyl coa hydrolase M forcoa c + M h2o c −→ M coa c + M for c + L A T

E M h c X 405 R FDH formate dehydrogenase M for c + M nad c −→ M co2 c + M nadh c 406 R FE2abc iron (II) transport via ABC system M atp c + M fe2 e + M h2o c −→ M adp c + M fe2 c + M h c + M pi c 407 R FE3Ri Fe(III) reduction M fadh2 c + 2 M fe3 c −→ M fad c + 2 M fe2 c + 2 M h c 408 R FE3abc iron (III) transport via ABC system M atp c + M fe3 e + M h2o c −→ M adp c + M fe3 c + M h c + M pi c 409 R FETRANS Mycobactin Fe transfer M fmcbtt c )−−−−* M fe2 c + M mcbtt c 410 R FHL Formate-hydrogen lyase M for c + M h c −→ M co2 c + M h2 c 411 R FMETTRS Methionyl-tRNA formyltransferase M 10fthf c + M mettrna c −→ M fmettrna c + M h c + M thf c 71 72 o N¯ Id Name Reaction Equation SBO 412 R FMNAT FMN adenylyltransferase M atp c + M fmn c + M h c −→ M fad c + M ppi c 413 R FOLD3 dihydropteroate synthase M 2ahhmd c + M 4abz c −→ M dhpt c + M ppi c 414 R FOLR2 folate reductase M fol c + M nadph c −→ M dhf c + M nadp c 415 R FOMETR aminomethyltransferase M 5fthf c + M h c )−−−−* M h2o c + M methf c 416 R FORMCOAL formyl-coa–CoA ligase M atp c + M coa c + M for c )−−−−* M amp c + M forcoa c + M ppi c 417 R FRD fumarate reductase M fadh2 c + M fum c −→ M fad c + M succ c 418 R FRD2 fumarate reductase M fum c + M mql8 c −→ M mqn8 c + M succ c

rdcdby Produced 419 R FRD3 fumarate reductase M 2dmmql8 c + M fum c −→ M 2dmmq8 c + M succ c 420 R FRD5 fumarate reductase M fum c + M mql6 c )−−−−* M mqn6 c + M succ c 421 R FRDO2r ferredoxin oxidoreductase M adfdRD c + 2 M nadp c )−−−−* M adfdOX c + 2 M nadph c SBML 422 R FRDO3r ferredoxin oxidoreductase M adfdRD c + 2 M nad c )−−−−* M adfdOX c +

2 2 M nadh c L A T + −−* + + E 423 R FRDOr ferredoxin oxidoreductase M fdxrd c M nadp c )−− M fdxox c M h c X M nadph c 424 R FRRPPDIMAS fucose rhamnose rhamnose phenol phthio- M gdpfuc c + M rrppdima c −→ M frrppdima c + cerol dimycocerosate synthesis M gdp c + M h c 425 R FTHFCL 5-formethyltetrahydrofolate cyclo-ligase M 5fthf c + M atp c −→ M adp c + M methf c + M pi c 426 R FTHFD formyltetrahydrofolate deformylase M 10fthf c + M h2o c −→ M for c + M h c + M thf c 427 R FTHFL formate-tetrahydrofolate ligase M atp c + M for c + M thf c )−−−−* M 10fthf c + M adp c + M pi c 428 R FUM fumarase M fum c + M h2o c )−−−−* M mal DASH L c 429 R FUMt2r fumarate reversible transport via symport M fum e + M h e )−−−−* M fum c + M h c o N¯ Id Name Reaction Equation SBO 430 R G16MTM1 Glycolipid 1,6-alpha-D-mannosyltransferase M gdpmann c+M ptd1ino160190 c −→ M PIM1 c+ M gdp c + M h c 431 R G16MTM10 Glycolipid 16-alpha-D-mannosyltransferase M PIM5 c + M gdpmann c −→ M PIM6 c + M gdp c + M h c 432 R G16MTM2 Glycolipid 16-alpha-D-mannosyltransferase M Ac1PIM1 c+M gdpmann c −→ M Ac1PIM2 c+ M gdp c + M h c 433 R G16MTM4 Glycolipid 16-alpha-D-mannosyltransferase M Ac1PIM2 c+M decdman1p tb c −→ M Ac1PIM3 c+ M decd tb c + M h c 434 R G16MTM5 Glycolipid 16-alpha-D-mannosyltransferase M Ac1PIM3 c+M decdman1p tb c −→ M Ac1PIM4 c+

rdcdby Produced M decd tb c + M h c 435 R G16MTM6 Glycolipid 16-alpha-D-mannosyltransferase M PIM1 c + M gdpmann c −→ M PIM2 c + M gdp c + M h c 436 R G16MTM7 Glycolipid 16-alpha-D-mannosyltransferase M PIM2 c + M gdpmann c −→ M PIM3 c + M gdp c + M h c SBML 437 R G16MTM8 Glycolipid 16-alpha-D-mannosyltransferase M PIM3 c + M gdpmann c −→ M PIM4 c +

2 M gdp c + M h c L A T + −→ + E 438 R G16MTM9 Glycolipid 16-alpha-D-mannosyltransferase M PIM4 c M gdpmann c M PIM5 c X M gdp c + M h c 439 R G1PACT glucosamine-1-phosphate N- M accoa c + M gam1p c −→ M acgam1p c + acetyltransferase M coa c + M h c 440 R G1PTT glucose-1-phosphate thymidylyltransferase M dttp c + M g1p c + M h c −→ M dtdpglu c + M ppi c 441 R G1SATi glutamate-1-semialdehyde aminotransferase M glu1sa c −→ M 5aop c 442 R G3PAT160 glycerol-3-phosphate acyltransferase (C16:0) M glyc3p c + M palmACP c −→ M 1hdecg3p c + M ACP c 443 R G3PAT190 glycerol-3-phosphate acyltransferase (C19:0) M glyc3p c + M mstrACP c −→ M 1msg3p c + M ACP c 444 R G3PD1 glycerol-3-phosphate dehydrogenase (NAD) M glyc3p c + M nad c )−−−−* M dhap c + M h c + 73 M nadh c 74 o N¯ Id Name Reaction Equation SBO 445 R G5SADs L-glutamate 5-semialdehyde dehydratase M glu5sa c −→ M 1pyr5c c + M h2o c + M h c (spontaneous) 446 R G5SD glutamate-5-semialdehyde dehydrogenase M glu5p c + M h c + M nadph c −→ M glu5sa c + M nadp c + M pi c 447 R G5SD2 glutamate-5-semialdehyde dehydrogenase M glu5p c + M h c + M nadh c −→ M glu5sa c + M nad c + M pi c 448 R G6PDH2 glucose 6-phosphate dehydrogenase M g6p c + M nadp c −→ M 6pgl c + M h c + M nadph c 449 R GALFT galactofuranose transferse (M tb) M h2o c + M ragund c +

rdcdby Produced 30 M udpgalfur c −→ M galfragund c + 30 M h c + 30 M udp c 450 R GALKr galactokinase M atp c + M gal c )−−−−* M adp c + M gal1p c + M h c 451 R GALT galactose-1-phosphate uridylyltransferase M gal1p c + M h c + M utp c )−−−−* M ppi c + SBML M udpgal c

2 452 R GALUi UTP-glucose-1-phosphate uridylyltransferase M g1p c + M h c + M utp c −→ M ppi c + L A T

E (irreversible) M udpg c X 453 R GALt2 D-galactose transport in via proton symport M gal e + M h e −→ M gal c + M h c 454 R GAPD glyceraldehyde-3-phosphate dehydrogenase M g3p c + M nad c + M pi c )−−−−* M 13dpg c + M h c + M nadh c 455 R GARFT phosphoribosylglycinamide formyltrans- M 10fthf c + M gar c )−−−−* M fgam c + M h c + ferase M thf c 456 R GCC2 glycine-cleavage system (lipoamide) irre- M alpam c + M thf c −→ M dhlam c + versible M mlthf c + M nh4 c 457 R GCCa glycine-cleavage complex M gly c + M h c + M lpro c −→ M alpro c + M co2 c 458 R GCCb glycine cleavage complex M alpro c + M thf c −→ M dhlpro c + M mlthf c + M nh4 c o N¯ Id Name Reaction Equation SBO 459 R GCCc glycine-cleavage complex M dhlpro c + M nad c −→ M h c + M lpro c + M nadh c 460 R GF6PTAr Glutamine-fructose-6-phosphate transami- M f6p c + M gln DASH L c )−−−−* M gam6p c + nase M glu DASH L c 461 R GFUCS GDP-L-fucose synthase M gdpddman c + M h c + M nadph c −→ M gdpfuc c + M nadp c 462 R GGLUCT2 gamma-glutamylcyclotransferase M gluala c −→ M 5oxpro c + M ala DASH L c 463 R GHMT2 glycine hydroxymethyltransferase M ser DASH L c + M thf c −→ M gly c + M h2o c + M mlthf c

rdcdby Produced 464 R GK1 guanylate kinase (GMP:ATP) M atp c + M gmp c )−−−−* M adp c + M gdp c 465 R GLCP glycogen phosphorylase M glycogen c + M pi c −→ M g1p c 466 R GLCS1 glycogen synthase (ADPGlc) M adpglc c −→ M adp c + M glycogen c + M h c 467 R GLCabc D-glucose transport via ABC system M atp c + M glc DASH D e + M h2o c −→ M adp c + M glc DASH D c + SBML M h c + M pi c

2 468 R GLGC glucose-1-phosphate adenylyltransferase M atp c + M g1p c + M h c −→ M adpglc c + L A T

E M ppi c X 469 R GLNS glutamine synthetase M atp c + M glu DASH L c + M nh4 c −→ M adp c + M gln DASH L c + M h c + M pi c 470 R GLNSP1 glutamine synthetase (uaaAgld) M atp c + M nh4 c + M uaaAgla c −→ M adp c + M h c + M pi c + M uaaAgtla c 471 R GLNSP2 glutamine synthetase (uaaGgla) M atp c + M nh4 c + M uaaGgla c −→ M adp c + M h c + M pi c + M uaaGgtla c 472 R GLNSP3 glutamine synthetase (uaagmda) M atp c+M nh4 c+M uaagmda c −→ M adp c+ M h c + M pi c + M uaagtmda c 473 R GLU5K glutamate 5-kinase M atp c + M glu DASH L c −→ M adp c + M glu5p c 75 76 o N¯ Id Name Reaction Equation SBO 474 R GLUCYS gamma-glutamylcysteine synthetase M atp c + M cys DASH L c + M glu DASH L c −→ M adp c + M glucys c + M h c + M pi c 475 R GLUDC Glutamate Decarboxylase M glu DASH L c + M h c −→ M 4abut c + M co2 c 476 R GLUDx glutamate dehydrogenase (NAD) M glu DASH L c + M h2o c + M nad c )−−−−* M akg c + M h c + M nadh c + M nh4 c 477 R GLUPRT glutamine phosphoribosyldiphosphate ami- M gln DASH L c + M h2o c +

rdcdby Produced dotransferase M prpp c −→ M glu DASH L c + M ppi c + M pram c 478 R GLUR glutamate racemase M glu DASH D c )−−−−* M glu DASH L c 479 R GLUSy glutamate synthase (NADPH) M akg c + M gln DASH L c + M h c + M nadph c −→ 2 M glu DASH L c + M nadp c SBML 480 R GLUTRR glutamyl-tRNA reductase M glutrna c + M h c +

2 M nadph c −→ M glu1sa c + M nadp c + L A T

E M trnaglu c X 481 R GLUt2r L-glutamate transport via proton symport, re- M glu DASH L e + versible M h e )−−−−* M glu DASH L c + M h c 482 R GLXO1 glyoxylate oxidase M glx c + M h2o c + M nad c −→ 2 M h c + M nadh c + M oxa c 483 R GLYBabc Glycine betaine transport via ABC system M atp c + M glyb e + M h2o c −→ M adp c + M glyb c + M h c + M pi c 484 R GLYC3Pabc sn-Glycerol 3-phosphate transport via ABC M atp c + M glyc3p e + M h2o c −→ M adp c + system M glyc3p c + M h c + M pi c 485 R GLYCK glycerate kinase M atp c + M glyc DASH R c −→ M 3pg c + M adp c + M h c 486 R GLYCL Glycine Cleavage System M gly c + M nad c + M thf c −→ M co2 c + M mlthf c + M nadh c + M nh4 c o N¯ Id Name Reaction Equation SBO 487 R GLYCTO1 Glycolate oxidase M glyclt c + M o2 c −→ M glx c + M h2o2 c 488 R GLYCTO2 Glycolate oxidase M glyclt c + M q8 c −→ M glx c + M q8h2 c 489 R GLYCTO3 Glycolate oxidase M glyclt c + M mqn8 c −→ M glx c + M mql8 c 490 R GLYCTO4 Glycolate oxidase M 2dmmq8 c + M glyclt c −→ M 2dmmql8 c + M glx c 491 R GLYCt glycerol transport via channel M glyc c )−−−−* M glyc e 492 R GLYK glycerol kinase M atp c + M glyc c −→ M adp c + M glyc3p c + M h c 493 R GLYt2r glycine reversible transport via proton sym- M gly e + M h e )−−−−* M gly c + M h c

rdcdby Produced port 494 R GMAND GDP-D-mannose dehydratase M gdpmann c −→ M gdpddman c + M h2o c 495 R GMPS2 GMP synthase M atp c + M gln DASH L c + M h2o c + M xmp c −→ M amp c + M glu DASH L c + M gmp c + 2 M h c + M ppi c SBML 496 R GMT1 gdp mannosyl phosphate transferase M decd tb c+M gdpmann c −→ M decdman1p tb c+

2 M gdp c L A T + −→ + E 497 R GMT2 gdp mannosyl phosphate transferase 3 M gdpmann c M harab DASH D c 3 M gdp c X 3 M h c + M mharab DASH D c 498 R GND phosphogluconate dehydrogenase M 6pgc c+M nadp c −→ M co2 c+M nadph c+ M ru5p DASH D c 499 R GPDDA2 Glycerophosphodiester phosphodiesterase M g3pe c + M h2o c −→ M etha c + (Glycerophosphoethanolamine) M glyc3p c + M h c 500 R GRTT geranyltranstransferase M grdp c + M ipdp c −→ M frdp c + M ppi c 501 R GSNK guanosine kinase M atp c + M gsn c −→ M adp c + M gmp c + M h c 502 R GTHOr glutathione oxidoreductase M gthox c + M h c + M nadph c )−−−−* 2 M gthrd c + M nadp c 503 R GTHRDt2 glutathione transport M gthrd e −→ M gthrd c 77 78 o N¯ Id Name Reaction Equation SBO 504 R GTHS glutathione synthetase M atp c + M glucys c + M gly c −→ M adp c + M gthrd c + M h c + M pi c 505 R GTMLT g-glutamyltransferase M ala DASH L c + M gthrd c −→ M cgly c + M gluala c 506 R GTPCI GTP cyclohydrolase I M gtp c + M h2o c −→ M ahdt c + M for c + M h c 507 R GTPCII GTP cyclohydrolase II M gtp c+3 M h2o c −→ M 25dhpp c+M for c+ 2 M h c + M ppi c 508 R GTPCII2 GTP cyclohydrolase II (25drapp) M gtp c + 3 M h2o c −→ M 25drapp c +

rdcdby Produced M for c + 2 M h c + M ppi c 509 R GTPDPK GTP diphosphokinase M atp c + M gtp c −→ M amp c + M gdptp c + M h c 510 R GTPH1 GTP diphosphohydrolase M gtp c + 2 M h2o c −→ M gmp c + 2 M h c + 2 M pi c SBML 511 R GUACYC guanylate cyclase M gtp c −→ M 35cgmp c + M ppi c

2 512 R GUAD guanine deaminase M gua c + M h2o c + M h c −→ M nh4 c + L A T

E M xan c X 513 R GUAPRT guanine phosphoribosyltransferase M gua c + M prpp c −→ M gmp c + M ppi c 514 R H2CO3D carboxylic acid dissociation M co2 c + M h2o c )−−−−* M h2co3 c 515 R H2CO3TP H2CO3 transport M h2co3 e )−−−−* M h2co3 c 516 R H2Ot H2O transport via diffusion M h2o e )−−−−* M h2o c 517 R H2St1 h2s transport M h2s c −→ M h2s e 518 R H2td hydrogen transport M h2 c )−−−−* M h2 e 519 R HAS hexa-arabinofuranoside synthesis M arab DASH D c + 5 M decda tb c −→ 5 M decd tb c + M harab DASH D c 520 R HCO3E HCO3 equilibration reaction M co2 c + M h2o c )−−−−* M h c + M hco3 c 521 R HCYSMT homocysteine S-methyltransferase M amet c + M hcys DASH L c −→ M ahcys c + M h c + M met DASH L c o N¯ Id Name Reaction Equation SBO 522 R HDCAt2 Hexadecanoate transport via proton symport M h e + M hdca e −→ M h c + M hdca c 523 R HEX1 hexokinase (D-glucose:ATP) M atp c + M glc DASH D c −→ M adp c + M g6p c + M h c 524 R HISTD histidinol dehydrogenase M h2o c + M histd c + 2 M nad c −→ 3 M h c + M his DASH L c + 2 M nadh c 525 R HISTP histidinol-phosphatase M h2o c + M hisp c −→ M histd c + M pi c 526 R HISt2r L-histidine reversible transport via proton M h e + M his DASH L e )−−−−* M h c + symport M his DASH L c 527 R HMBS hydroxymethylbilane synthase M h2o c + 4 M ppbng c −→ M hmbil c +

rdcdby Produced 4 M nh4 c 528 R HMPK1 hydroxymethylpyrimidine kinase (ATP) M 4ahmmp c + M atp c −→ M 4ampm c + M adp c + M h c 529 R HMPK2 hydroxymethylpyrimidine kinase (CTP) M 4ahmmp c + M ctp c −→ M 4ampm c + M cdp c + M h c SBML 530 R HMPK3 hydroxymethylpyrimidine kinase (UTP) M 4ahmmp c + M utp c −→ M 4ampm c +

2 M h c + M udp c L A T + −→ + E 531 R HMPK4 hydroxymethylpyrimidine kinase (GTP) M 4ahmmp c M gtp c M 4ampm c X M gdp c + M h c 532 R HOPNTAL 4-hydroxy-2-oxopentanoate aldolase M 4h2opntn c −→ M acald c + M pyr c 533 R HPPK 2-amino-4-hydroxy-6- M 2ahhmp c + M atp c −→ M 2ahhmd c + hydroxymethyldihydropteridine diphos- M amp c + M h c phokinase 534 R HPPK2 6-hydroxymethyl-dihydropterin pyrophos- M 6hmhpt c + M atp c −→ M 6hmhptpp c + phokinase M amp c + M h c 535 R HSDx homoserine dehydrogenase (NADH) M hom DASH L c + M nad c )−−−−* M aspsa c + M h c + M nadh c 536 R HSDy homoserine dehydrogenase (NADPH) M hom DASH L c + M nadp c )−−−−* M aspsa c + M h c + M nadph c 79 80 o N¯ Id Name Reaction Equation SBO 537 R HSERTA homoserine O-trans-acetylase M accoa c+M hom DASH L c )−−−−* M achms c+ M coa c 538 R HSK homoserine kinase M atp c + M hom DASH L c −→ M adp c + M h c + M phom c 539 R HSST homoserine O-succinyltransferase M hom DASH L c + M succoa c −→ M coa c + M suchms c 540 R HSTPT histidinol-phosphate transaminase M glu DASH L c + M imacp c −→ M akg c + M hisp c 541 R HXPRT hypoxanthine phosphoribosyltransferase M hxan c + M prpp c −→ M imp c + M ppi c

rdcdby Produced (Hypoxanthine) 542 R IACGAMS 1D-myo-inositol 2-Acetamido-2-deoxy-D- M acgam c+M mi1p DASH D c −→ M iacgam c+ glucopyranoside synthesis M pi c 543 R ICDHy isocitrate dehydrogenase (NADP) M icit c + M nadp c −→ M akg c + M co2 c + M nadph c SBML 544 R ICHORSi Isochorismate Synthase M chor c −→ M ichor c

2 545 R ICL Isocitrate lyase M icit c −→ M glx c + M succ c L A

T −−*

E 546 R ID3ACALDt Indoleacetaldehyde transport (extracellular) M id3acald c )−− M id3acald e X 547 R IG3PS Imidazole-glycerol-3-phosphate synthase M gln DASH L c + M prlp c −→ M aicar c + M eig3p c + M glu DASH L c + M h c 548 R IGAMD 1D-myo-inositol 2-Acetamido-2-deoxy-D- M h2o c + M iacgam c −→ M ac c + M igam c glucopyranoside deacetylase 549 R IGPDH imidazoleglycerol-phosphate dehydratase M eig3p c −→ M h2o c + M imacp c 550 R IGPS indole-3-glycerol-phosphate synthase M 2cpr5p c + M h c −→ M 3ig3p c + M co2 c + M h2o c 551 R ILETA isoleucine transaminase M akg c + M ile DASH L c )−−−−* M 3mop c + M glu DASH L c 552 R ILEt2r L-isoleucine reversible transport via proton M h e + M ile DASH L e )−−−−* M h c + symport M ile DASH L c 553 R IMPC IMP cyclohydrolase M h2o c + M imp c )−−−−* M fprica c o N¯ Id Name Reaction Equation SBO 554 R IMPD IMP dehydrogenase M h2o c + M imp c + M nad c −→ M h c + M nadh c + M xmp c 555 R INDPYRD Indole-3-pyruvate decarboxylase M h c + M indpyr c )−−−−* M co2 c + M id3acald c 556 R INSH Inosine hydrolase M h2o c + M ins c −→ M hxan c + M rib DASH D c 557 R INSK insosine kinase M atp c + M ins c −→ M adp c + M h c + M imp c 558 R IPDDI isopentenyl-diphosphate D-isomerase M ipdp c )−−−−* M dmpp c 559 R IPDPS 1-hydroxy-2-methyl-2-(E)-butenyl 4- M h2mb4p c + M h c + M nadh c −→ M h2o c +

rdcdby Produced diphosphate reductase (ipdp) M ipdp c + M nad c 560 R IPMD 3-isopropylmalate dehydrogenase M 3c2hmp c + M nad c −→ M 3c4mop c + M h c + M nadh c 561 R IPPMIa 3-isopropylmalate dehydratase M 3c2hmp c )−−−−* M 2ippm c + M h2o c 562 R IPPMIb 2-isopropylmalate hydratase M 2ippm c + M h2o c )−−−−* M 3c3hmp c SBML 563 R IPPS 2-isopropylmalate synthase M 3mob c + M accoa c +

2 M h2o c −→ M 3c3hmp c + M coa c + M h c L A T + + E 564 R KARA1i acetohydroxy acid isomeroreductase M alac DASH S c M h c X M nadph c −→ M 23dhmb c + M nadp c 565 R KARA2i ketol-acid reductoisomerase (2-Aceto-2- M 2ahbut c + M h c + hydroxybutanoate) M nadph c −→ M 23dhmp c + M nadp c 566 R Kabc Potassium ABC transporter M atp c + M h2o c + M k e −→ M adp c + M h c + M k c + M pi c 567 R Kt3r potassium proton antiporter M h e + M k c )−−−−* M h c + M k e 568 R LACZ b-galactosidase M h2o c + M lcts c −→ M gal c + M glc DASH D c 569 R LCTSabc lactose transport via ABC system (import) M atp c + M h2o c + M lcts e −→ M adp c + M h c + M lcts c + M pi c 570 R LDH L L-lactate dehydrogenase M lac DASH L c + M nad c )−−−−* M h c + 81 M nadh c + M pyr c 82 o N¯ Id Name Reaction Equation SBO 571 R LEUTA leucine transaminase M akg c + M leu DASH L c )−−−−* M 4mop c + M glu DASH L c 572 R LEUt2r L-leucine reversible transport via proton sym- M h e + M leu DASH L e )−−−−* M h c + port M leu DASH L c 573 R LO L-lactate oxidase M lac DASH L c + M o2 c −→ M ac c + M co2 c + M h2o c 574 R LPLIPAL2E160 Lysophospholipase L2 (2- M 2agpe160 c + M h2o c −→ M g3pe c + acylglycerophosphoethanolamine, n-C16:0) M h c + M hdca c 575 R LPLIPAL2E180 Lysophospholipase L2 (2- M 2agpe180 c + M h2o c −→ M g3pe c +

rdcdby Produced acylglycerophosphoethanolamine, n-C18:0) M h c + M ocdca c 576 R LYSt5r L-lysine transport via diffusion M lys DASH L e )−−−−* M lys DASH L c 577 R L LACD L-Lactate dehydrogenase irreversible 2 M ﬁcytc c+M lac DASH L c −→ 2 M focytc c+ M pyr c 578 R L LACD2 L-Lactate dehydrogenase (ubiquinone) M lac DASH L c + M q8 c −→ M pyr c + SBML M q8h2 c

2 579 R L LACD3 L-Lactate dehydrogenase (menaquinone) M lac DASH L c + M mqn8 c −→ M mql8 c + L A T

E M pyr c X 580 R L LACt2r L-lactate reversible transport via proton sym- M h e + M lac DASH L e )−−−−* M h c + port M lac DASH L c 581 R L LACt3 L-lactate transport out via proton antiport M h e + M lac DASH L c −→ M h c + M lac DASH L e 582 R MALS malate synthase M accoa c + M glx c + M h2o c −→ M coa c + M h c + M mal DASH L c 583 R MALT alpha-glucosidase M h2o c + M malt c −→ 2 M glc DASH D c 584 R MALTHPabc maltoheptaose transport via ABC system M atp c + M h2o c + M malthp e −→ M adp c + M h c + M malthp c + M pi c 585 R MALTabc maltose transport via ABC system M atp c + M h2o c + M malt e −→ M adp c + M h c + M malt c + M pi c o N¯ Id Name Reaction Equation SBO 586 R MALt2r L-malate reversible transport via proton sym- M h e + M mal DASH L e )−−−−* M h c + port M mal DASH L c 587 R MAN1PT mannose-1-phosphate guanylyltransferase M gtp c + M h c + M man1p c −→ M gdpmann c + M ppi c 588 R MAN1PT2 mannose-1-phosphate guanylyltransferase M gdp c + M h c + (GDP) M man1p c −→ M gdpmann c + M pi c 589 R MAN6PI mannose-6-phosphate isomerase M man6p c )−−−−* M f6p c 590 R MANAT1 mannosyl acyl transferase M PIM1 c + M pmtcoa c −→ M Ac1PIM1 c + M coa c

rdcdby Produced 591 R MANAT2 mannosyl acyl transferase M PIM2 c + M pmtcoa c −→ M Ac1PIM2 c + M coa c 592 R MANAT3 mannosyl acyl transferase M Ac1PIM2 c+M pmtcoa c −→ M Ac2PIM2 c+ M coa c 593 R MCBTS mycobactin synthesis M atp c + M bhb c + M h c + SBML 2 M lys DASH L c + 2 M o2 c + M odecoa c +

2 M salc c + M thr DASH L c −→ M adp c + L A T + + + + E M co2 c M coa c 5 M h2o c M mcbts c X M pi c 594 R MCBTS2 mycobactin synthesis M atp c + M bhb c + M h c + 2 M lys DASH L c + 2 M o2 c + M odecoa c + M salc c + M ser DASH L c −→ M adp c + M co2 c + M coa c + 5 M h2o c + M mcbtt c + M pi c 595 R MCBTS3 carboxymycobactin synthesis M atp c + M bhb c + 2 M lys DASH L c + 2 M nadp c + 3 ·5 M o2 c + M occoa c + M salc c + M ser DASH L c −→ M adp c + M cmcbtt c + M co2 c + M coa c + 5 M h2o c + 2 M h c + 2 M nadph c + M pi c 83 596 R MCD Malonyl-CoA Decarboxylase cytoplasmic M h c + M malcoa c −→ M accoa c + M co2 c 84 o N¯ Id Name Reaction Equation SBO 597 R MCOATA Malonyl-CoA-ACP transacylase M ACP c + M malcoa c )−−−−* M coa c + M malACP c 598 R MDFDH mycothiol dependent formaldehyde dehydro- M mshfald c + M nad c )−−−−* M h c + genase M mshfaldox c + M nadh c 599 R MDH malate dehydrogenase M mal DASH L c + M nad c )−−−−* M h c + M nadh c + M oaa c 600 R ME1 malic enzyme (NAD) M mal DASH L c + M nad c −→ M co2 c + M nadh c + M pyr c 601 R MECDPDH 2C-methyl-D-erythritol 2,4 cyclodiphosphate M 2mecdp c + M h c −→ M h2mb4p c + M h2o c

rdcdby Produced dehydratase 602 R MECDPS 2-C-methyl-D-erythritol 2,4- M 2p4c2me c −→ M 2mecdp c + M cmp c cyclodiphosphate synthase 603 R MEOHt2 Methanol diffusion M meoh e )−−−−* M meoh c 604 R MEPCT 2-C-methyl-D-erythritol 4-phosphate cytidy- M 2me4p c + M ctp c + M h c −→ M 4c2me c + SBML lyltransferase M ppi c

2 605 R METAT methionine adenosyltransferase M atp c + M h2o c + L A T −→ + + E M met DASH L c M amet c M pi c X M ppi c 606 R METOX1s methionine oxidation (spontaneous) M h2o2 c + M met DASH L c −→ M h2o c + M metsox DASH S DASH L c 607 R METOX2s methionine oxidation 2 (spontaneous) M h2o2 c + M met DASH L c −→ M h2o c + M metsox DASH R DASH L c 608 R METS methionine synthase M 5mthf c + M hcys DASH L c −→ M h c + M met DASH L c + M thf c 609 R METSOXR1 L-methionine-S-oxide reductase M metsox DASH S DASH L c + M trdrd c −→ M h2o c + M met DASH L c + M trdox c o N¯ Id Name Reaction Equation SBO 610 R METSOXR2 L-methionine-R-sulfoxide reductase M metsox DASH R DASH L c + M trdrd c −→ M h2o c + M met DASH L c + M trdox c 611 R METabc L-methionine transport via ABC system M atp c + M h2o c + M met DASH L e −→ M adp c + M h c + M met DASH L c + M pi c 612 R MGt5 magnesium transport in/out via permease (no M mg2 c )−−−−* M mg2 e H+) 613 R MHPGLUT 5-methyltetrahydropteroyltriglutamate- M hcys DASH L c +

rdcdby Produced homocysteine S-methyltransferase M mhpglu c −→ M hpglu c + M met DASH L c 614 R MI1PP myo-inositol 1-phosphatase M h2o c + M mi1p DASH D c −→ M inost c + M pi c 615 R MI1PS myo-Inositol-1-phosphate synthase M g6p c −→ M mi1p DASH D c 616 R MI3PP myo-inositol 3-phosphatase M h2o c + M mi3p DASH D c −→ M inost c + SBML M pi c

2 617 R MI4PP myo-inositol 4-phosphatase M h2o c + M mi4p DASH D c −→ M inost c + L A T

E M pi c X 618 R MMCD Methylmalonyl-CoA decarboxylase M h c + M mmcoa DASH S c −→ M co2 c + M ppcoa c 619 R MME methylmalonyl-CoA epimerase M mmcoa DASH R c )−−−−* M mmcoa DASH S c 620 R MMM2r Methylmalonyl-CoA mutase M succoa c )−−−−* M mmcoa DASH R c 621 R MMSAD1 methylmalonate-semialdehyde dehydroge- M 2mop c + M coa c + M nad c −→ M co2 c + nase M nadh c + M ppcoa c 622 R MMSAD2 methylmalonate-semialdehyde dehydroge- M coa c + M nad c + M ppal c −→ M h c + nase (propanol) M nadh c + M ppcoa c 623 R MMSAD3 methylmalonate-semialdehyde dehydroge- M coa c + M msa c + M nad c −→ M accoa c + nase (malonic semialdehyde) M co2 c + M nadh c 624 R MN6PP mannose 6-phosphate phosphatase M h2o c + M man6p c −→ M man c + M pi c 85 86 o N¯ Id Name Reaction Equation SBO 625 R MNDNS1 menadione synthase M dhna c + 3 M h c + 2 M nadph c −→ 2 M h2o c + M mndn c + 2 M nadp c 626 R MNDNS2 menadione synthase M dhna c + 3 M h c + 2 M nadh c −→ 2 M h2o c + M mndn c + 2 M nad c 627 R MOHMT 3-methyl-2-oxobutanoate hydroxymethyl- M 3mob c + M h2o c + transferase M mlthf c −→ M 2dhp c + M thf c 628 R MOTH maltooligosyltrehalose trehalohydrolase M h2o c + M motre c −→ M maltpt c + M tre c

rdcdby Produced 629 R MOTS maltooligosyltrehalose synthase M malthp c −→ M motre c 630 R MPML Mg-protoporphyrin IX magnesium-lyase M atp c + M h2o c + M mg2 c + M ppp9 c )−−−−* M adp c + 3 M h c + M mppp9 c + M pi c 631 R MSHAMID conjugated glutathione amidase (Mtb) M bmnmsh c + M h2o c −→ M acysbmn c + SBML M igam c

2 632 R MSHOXH mshfaldox hydrolysis (Mtb) M h2o c + M mshfaldox c −→ M for c + M h c + L A T

E M msh c X 633 R MSHS mycothiol synthase M accoa c + M cigam c −→ M coa c + M msh c 634 R MTAN methylthioadenosine nucleosidase M 5mta c + M h2o c −→ M 5mtr c + M ade c 635 R MTHFC methenyltetrahydrofolate cyclohydrolase M h2o c + M methf c )−−−−* M 10fthf c + M h c 636 R MTHFD methylenetetrahydrofolate dehydrogenase M mlthf c + M nadp c )−−−−* M methf c + (NADP) M nadph c 637 R MTHFD2 methylenetetrahydrofolate dehydrogenase M mlthf c + M nad c )−−−−* M methf c + M nadh c (NAD) 638 R MTHFR2 5,10-methylenetetrahydrofolate reductase 2 M h c+M mlthf c+M nadh c −→ M 5mthf c+ (NADH) M nad c 639 R MTI maltose trehalose isomerase M tre c )−−−−* M malt c 640 R MYC1CYC1 Mycolic Acid Cyclopropanation M amet c + M meroacidACP c −→ M ahcys c + M h c + M meroacidcyc1ACP c o N¯ Id Name Reaction Equation SBO 641 R MYC1CYC2 Mycolic Acid Cyclopropanation M amet c + M mmeroacidACP c −→ M ahcys c + M h c + M mmeroacidcyc1ACP c 642 R MYC1CYC3 Mycolic Acid Cyclopropanation M amet c + M kmeroacidACP c −→ M ahcys c + M h c + M kmeroacidcyc1ACP c 643 R MYC1CYC4 Mycolic Acid Cyclopropanation M amet c+M mmmeroacidACP c −→ M ahcys c+ M h c + M mmmeroacidcyc1ACP c 644 R MYC1CYC5 Mycolic Acid Cyclopropanation M amet c+M mkmeroacidACP c −→ M ahcys c+ M h c + M mkmeroacidcyc1ACP c 645 R MYC1M1 Mycolic Acid Methyl Hydroxyl Addition M amet c + M h2o c +

rdcdby Produced M mmeroacidACP c −→ M ahcys c + M h c + M mmmeroacidACP c 646 R MYC1M2 Mycolic Acid Methyl Hydroxyl Addition M amet c + M h2o c + M kmeroacidACP c −→ M ahcys c + M h c + M mkmeroacidACP c SBML 647 R MYC2CYC1 Mycolic Acid Cyclopropanation M amet c+M meroacidcyc1ACP c −→ M ahcys c+

2 M h c + M meroacidcyc2ACP c L A T + −→ + E 648 R MYC2CYC2 Mycolic Acid Cyclopropanation M amet c M mmeroacidcyc1ACP c M ahcys c X M h c + M mmeroacidcyc2ACP c 649 R MYC2CYC3 Mycolic Acid Cyclopropanation M amet c+M kmeroacidcyc1ACP c −→ M ahcys c+ M h c + M kmeroacidcyc2ACP c 650 R MYCFLUX1 mycolic acid conglomeration flux M mycolate c −→ M rmyc c 651 R MYCFLUX2 mycolic acid conglomeration flux M mmycolate c −→ M rmyc c 652 R MYCFLUX3 mycolic acid conglomeration flux M kmycolate c −→ M rmyc c 653 R MYCFLUX4 mycolic acid conglomeration flux M mmmycolate c −→ M rmyc c 654 R MYCFLUX5 mycolic acid conglomeration flux M mkmycolate c −→ M rmyc c 655 R MYCON1 Mycolic Acid Condensation M chexccoa c + 2 M h2o c + M meroacidcyc2AMP c −→ M amp c + M co2 c + M coa c + 2 M h c + M mycolate c 87 88 o N¯ Id Name Reaction Equation SBO 656 R MYCON2 Mycolic Acid Condensation M chexccoa c + 2 M h2o c + M mmeroacidcyc2AMP c −→ M amp c + M co2 c + M coa c + 2 M h c + M mmycolate c 657 R MYCON3 Mycolic Acid Condensation M chexccoa c + 2 M h2o c + M kmeroacidcyc2AMP c −→ M amp c + M co2 c + M coa c + 2 M h c + M kmycolate c 658 R MYCON4 Mycolic Acid Condensation M chexccoa c + 2 M h2o c + M mmmeroacidcyc1AMP c −→ M amp c + M co2 c + M coa c + 2 M h c + M mmmycolate c

rdcdby Produced 659 R MYCON5 Mycolic Acid Condensation M chexccoa c + 2 M h2o c + M mkmeroacidcyc1AMP c −→ M amp c + M co2 c + M coa c + 2 M h c + M mkmycolate c 660 R MYCSacp50 mycolic acid synthase (C50) 33 M h c + M hexc c + 12 M malACP c + 24 M nadph c −→ 11 M ACP c + 12 M co2 c + SBML 13 M h2o c + M meroacidACP c + 24 M nadp c

2 661 R MYCSacp56 mycolic acid synthase (C56) 42 M h c + M hexc c + 15 M malACP c + L A T −→ + + E 30 M nadph c 14 M ACP c 15 M co2 c X 16 M h2o c + M mmeroacidACP c + 30 M nadp c 662 R MYCSacp58 mycolic acid synthase (C58) 47 M h c + M hexc c + 16 M malACP c + 30 M nadph c −→ 15 M ACP c + 16 M co2 c + 17 M h2o c + M kmeroacidACP c + 30 M nadp c 663 R MYCTR mycothiol reductase (nadp dependent) 2 M msh c + M nadp c )−−−−* M h c + M mssg c + M nadph c 664 R MYCTR2 mycothiol reductase (glutathione exchange) M gthox c + 2 M msh c )−−−−* 2 M gthrd c + M mssg c 665 R NADH10 NADH dehydrogenase (menaquinone-8 & 0 M h c + M mqn8 c + M nadh c −→ M mql8 c + protons) M nad c 666 R NADH2r NADH dehydrogenase M h c + M nadh c + M q c )−−−−* M nad c + M qh2 c o N¯ Id Name Reaction Equation SBO 667 R NADH5 NADH dehydrogenase (ubiquinone-8 ) M h c + M nadh c + M q8 c −→ M nad c + M q8h2 c 668 R NADH9 NADH dehydrogenase M 2dmmq8 c + M h c + (demethylmenaquinone-8 & 0 protons) M nadh c −→ M 2dmmql8 c + M nad c 669 R NADK NAD kinase M atp c + M nad c −→ M adp c + M h c + M nadp c 670 R NADS2 NAD synthase (glutamine-hydrolysing) M atp c + M dnad c + M gln DASH L c + M h2o c −→ M amp c + M glu DASH L c + M h c + M nad c + M ppi c

rdcdby Produced 671 R NADTRHD NAD transhydrogenase M nad c + M nadph c −→ M nadh c + M nadp c 672 R NAKtr potassium sodium antiporter M k c + M na1 e )−−−−* M k e + M na1 c 673 R NAPRTr NAPRTase (rev) M h c + M nac c + M prpp c )−−−−* M nicrnt c + M ppi c 674 R NARK nark M no2 c −→ M no2 e SBML 675 R NAt3 1 sodium proton antiporter (H:NA is 1:1) M h e + M na1 c )−−−−* M h c + M na1 e

2 676 R NDPK1 nucleoside-diphosphate kinase (ATP:GDP) M atp c + M gdp c )−−−−* M adp c + M gtp c L A T + −−* + E 677 R NDPK2 nucleoside-diphosphate kinase (ATP:UDP) M atp c M udp c )−− M adp c M utp c X 678 R NDPK3 nucleoside-diphosphate kinase (ATP:CDP) M atp c + M cdp c )−−−−* M adp c + M ctp c 679 R NDPK4 nucleoside-diphosphate kinase (ATP:dTDP) M atp c + M dtdp c )−−−−* M adp c + M dttp c 680 R NDPK5 nucleoside-diphosphate kinase (ATP:dGDP) M atp c + M dgdp c )−−−−* M adp c + M dgtp c 681 R NDPK6 nucleoside-diphosphate kinase (ATP:dUDP) M atp c + M dudp c )−−−−* M adp c + M dutp c 682 R NDPK7 nucleoside-diphosphate kinase (ATP:dCDP) M atp c + M dcdp c )−−−−* M adp c + M dctp c 683 R NDPK8 nucleoside-diphosphate kinase (ATP:dADP) M atp c + M dadp c )−−−−* M adp c + M datp c 684 R NDPK9 nucleoside-diphosphate kinase (ATP:IDP) M atp c + M idp c )−−−−* M adp c + M itp c 685 R NH4OHDs NH4OH dissociation M h c + M nh4oh c )−−−−* M h2o c + M nh4 c 686 R NH4t ammonia reversible transport M nh4 e )−−−−* M nh4 c 687 R NNAM nicotinamidase M h2o c + M ncam c −→ M nac c + M nh4 c 688 R NNAT nicotinate-nucleotide adenylyltransferase M atp c + M h c + M nicrnt c −→ M dnad c + 89 M ppi c 90 o N¯ Id Name Reaction Equation SBO 689 R NNDMBRT Nicotinate-nucleotide dimethylbenzimida- M dmbzid c + M nicrnt c −→ M 5prdmbz c + zole phosphoribosyltransferase M h c + M nac c 690 R NNDPR nicotinate-nucleotide diphosphorylase (car- 2 M h c + M prpp c + M quln c −→ M co2 c + boxylating) M nicrnt c + M ppi c 691 R NO peroxynitrite formation (spontanous) M no c + M o2s c −→ M no3 c 692 R NO3R1 Nitrate reductase (Ubiquinol-8) 2 M h c + M no3 c + M q8h2 c −→ M h2o c + 2 M h e + M no2 c + M q8 c 693 R NO3R2 Nitrate reductase (Menaquinol-8) 2 M h c + M mql8 c + M no3 c −→ M h2o c + 2 M h e + M mqn8 c + M no2 c

rdcdby Produced 694 R NO3t7 nitrate transport in via nitrite antiport M no2 c + M no3 e −→ M no2 e + M no3 c 695 R NOt NO transport (diffusion) M no e )−−−−* M no c 696 R NPHS naphthoate synthase M sbzcoa c −→ M coa c + M dhna c 697 R NTD1 5’-nucleotidase (dUMP) M dump c + M h2o c −→ M duri c + M pi c 698 R NTD10 5’-nucleotidase (XMP) M h2o c + M xmp c −→ M pi c + M xtsn c SBML 699 R NTD11 5’-nucleotidase (IMP) M h2o c + M imp c −→ M ins c + M pi c

2 700 R NTD2 5’-nucleotidase (UMP) M h2o c + M ump c −→ M pi c + M uri c L A T + −→ + E 701 R NTD3 5’-nucleotidase (dCMP) M dcmp c M h2o c M dcyt c M pi c X 702 R NTD4 5’-nucleotidase (CMP) M cmp c + M h2o c −→ M cytd c + M pi c 703 R NTD5 5’-nucleotidase (dTMP) M dtmp c + M h2o c −→ M pi c + M thymd c 704 R NTD6 5’-nucleotidase (dAMP) M damp c + M h2o c −→ M dad DASH 2 c + M pi c 705 R NTD7 5’-nucleotidase (AMP) M amp c + M h2o c −→ M adn c + M pi c 706 R NTD8 5’-nucleotidase (dGMP) M dgmp c + M h2o c −→ M dgsn c + M pi c 707 R NTD9 5’-nucleotidase (GMP) M gmp c + M h2o c −→ M gsn c + M pi c 708 R NTPP2 Nucleoside triphosphate pyrophosphorylase M gtp c + M h2o c −→ M gmp c + M h c + (gtp) M ppi c 709 R NTPP3 Nucleoside triphosphate pyrophosphorylase M dctp c + M h2o c −→ M dcmp c + M h c + (dctp) M ppi c o N¯ Id Name Reaction Equation SBO 710 R NTPP4 Nucleoside triphosphate pyrophosphorylase M ctp c + M h2o c −→ M cmp c + M h c + (ctp) M ppi c 711 R NTPP5 Nucleoside triphosphate pyrophosphorylase M datp c + M h2o c −→ M damp c + M h c + (datp) M ppi c 712 R NTPP7 Nucleoside triphosphate pyrophosphorylase M dttp c + M h2o c −→ M dtmp c + M h c + (dttp) M ppi c 713 R NTPP8 Nucleoside triphosphate pyrophosphorylase M h2o c + M utp c −→ M h c + M ppi c + (utp) M ump c 714 R NTPTP1 Nucleoside triphosphate tripolyhydrolase M dgtp c + M h2o c −→ M dgsn c + M pppi c

rdcdby Produced 715 R NTPTP2 Nucleoside triphosphate tripolyhydrolase M gtp c + M h2o c −→ M gsn c + M pppi c 716 R NTRIR2x nitrite Reductase (NADH) 5 M h c + 3 M nadh c + M no2 c −→ 2 M h2o c + 3 M nad c + M nh4 c 717 R NTRIRx nitrite reductase (NADH) 4 M h c + 3 M nadh c + M no2 c −→ M h2o c + 3 M nad c + M nh4oh c SBML 718 R NTRIRy nitrite reductase (NADPH) 4 M h c + 3 M nadph c + M no2 c −→ M h2o c +

2 3 M nadp c + M nh4oh c L A T + −→ + E 719 R O16RHAT rhamnosyltransferase (LPS O16 antigen M dtdprmn c M unaga c M dtdp c X biosynthesis) M h c + M ragund c 720 R O2t o2 transport (diffusion) M o2 e )−−−−* M o2 c 721 R OCBT ornithine carbamoyltransferase M cbp c + M orn c )−−−−* M citr DASH L c + M h c + M pi c 722 R OCDCAt2 Octadecanoate transport via proton symport M h e + M ocdca e −→ M h c + M ocdca c 723 R OCOAT1r 3-oxoacid CoA-transferase (Succinyl-CoA: M acac c + M succoa c )−−−−* M aacoa c + acetoacetate) M succ c 724 R OCTDPS Octaprenyl pyrophosphate synthase M frdp c + 5 M ipdp c −→ M octdp c + 5 M ppi c 725 R OHPBAT O-Phospho-4-hydroxy-L-threonine:2- M glu DASH L c + M ohpb c )−−−−* M akg c + oxoglutarate aminotransferase M phthr c 726 R OMCDC 2-Oxo-4-methyl-3-carboxypentanoate decar- M 3c4mop c + M h c −→ M 4mop c + M co2 c 91 boxylation 92 o N¯ Id Name Reaction Equation SBO 727 R OMPDC orotidine-5’-phosphate decarboxylase M h c + M orot5p c −→ M co2 c + M ump c 728 R OPAH 5-Oxoproline amidohydrolase (ATP- M 5oxpro c + M atp c + hydrolysing) 2 M h2o c )−−−−* M adp c + M glu DASH L c + M h c + M pi c 729 R ORNTA ornithine transaminase M akg c + M orn c −→ M glu5sa c + M glu DASH L c 730 R ORNTAC ornithine transacetylase M acorn c + M glu DASH L c )−−−−* M acglu c + M orn c 731 R ORNt ornithine transport via diffusion (extracellular M orn e )−−−−* M orn c

rdcdby Produced to periplasm) 732 R ORPT orotate phosphoribosyltransferase M orot5p c + M ppi c )−−−−* M orot c + M prpp c 733 R OXACOAL oxalate-coa ligase M atp c + M coa c + M oxa c )−−−−* M amp c + M oxalcoa c + M ppi c 734 R OXCDC Oxalyl-CoA decarboxylase M h c + M oxalcoa c −→ M co2 c + M forcoa c SBML 735 R OXGDC 2-oxoglutarate decarboxylase M akg c + M h c −→ M co2 c + M sucsal c

2 736 R OXGDC2 2-oxoglutarate decarboxylase M akg c + M h c + M thmpp c −→ M co2 c + L A T

E M ssaltpp c X 737 R P5CD 1-pyrroline-5-carboxylate dehydrogenase M 1pyr5c c + 2 M h2o c + M nad c −→ M glu DASH L c + M h c + M nadh c 738 R P5CR pyrroline-5-carboxylate reductase M 1pyr5c c + 2 M h c + M nadph c −→ M nadp c + M pro DASH L c 739 R P5CRx pyrroline-5-carboxylate reductase M 1pyr5c c + 2 M h c + M nadh c −→ M nad c + M pro DASH L c 740 R PACt2r phenylacetate transport in via proton sym- M h e + M pac e )−−−−* M h c + M pac c porter 741 R PANTS pantothenate synthase M ala DASH B c + M atp c + M pant DASH R c −→ M amp c + M h c + M pnto DASH R c + M ppi c o N¯ Id Name Reaction Equation SBO 742 R PAPA160 Phosphatidate phosphatase (n-C16:0) M h2o c+M pa160 c −→ M 12dgr160 c+M pi c 743 R PAPPT1 phospho-N-acetylmuramoyl-pentapeptide- M uAgla c + M udcpp c −→ M uaAgla c + transferase (alpha-glutamate) M ump c 744 R PAPPT2 phospho-N-acetylmuramoyl-pentapeptide- M uGgla c + M udcpp c −→ M uaGgla c + transferase (gamma-glutamate) M ump c 745 R PAPPT3 phospho-N-acetylmuramoyl-pentapeptide- M udcpp c + M ugmda c −→ M uagmda c + transferase (meso-2,6-diaminopimelate) M ump c 746 R PAPR Phosphoadenosine phosphosulfate reductase M paps c + M trdrd c )−−−−* 2 M h c + M pap c + M so3 c + M trdox c

rdcdby Produced 747 R PATS penta-acyl trehalose synthesis 5 M h c + M ocdca c + 4 M tmlgnc c + M tre c −→ 5 M h2o c + M pat c 748 R PC pyruvate carboxylase M atp c + M hco3 c + M pyr c −→ M adp c + M h c + M oaa c + M pi c 749 R PC11M precorrin-4 C11-methyltransferase M amet c + M pre4 c −→ M ahcys c + M h c + SBML M pre5 c

2 750 R PC17M precorrin-3B C17-methyltransferase M amet c+M pre3b c −→ M ahcys c+3 M h c+ L A T

E M pre4 c X 751 R PC20M precorrin-2 C20-methyltransferase M amet c + M dscl c −→ M ahcys c + M h c + M pre3a c 752 R PC6AR precorrin-6A reductase M h c + M nadph c + M pre6a c −→ M nadp c + M pre6b c 753 R PC6YM precorrin-6Y C5,15-methyltransferase (de- 2 M amet c + M pre6b c −→ 2 M ahcys c + carboxylating) M co2 c + 2 M h c + M pre8 c 754 R PC8XM precorrin-8X methylmutase M h c + M pre8 c −→ M hgbyr c 755 R PDE1 3’,5’-cyclic-nucleotide phosphodiesterase M camp c + M h2o c −→ M amp c + M h c 756 R PDE4 3’,5’-cyclic-nucleotide phosphodiesterase M 35cgmp c + M h2o c −→ M gmp c + M h c 757 R PDH pyruvate dehydrogenase M coa c + M nad c + M pyr c −→ M accoa c + M co2 c + M nadh c 93 94 o N¯ Id Name Reaction Equation SBO 758 R PDHa pyruvate dehydrogenase (lipoamide) M h c + M lpam c + M pyr c −→ M adhlam c + M co2 c 759 R PDHbr pyruvate dehydrogenase (dihydrolipoamide) M adhlam c + M coa c )−−−−* M accoa c + reversible M dhlam c 760 R PDHc pyruvate dehydrogenase (dihydrolipoamide M dhlam c + M nad c −→ M h c + M lpam c + dehydrogenase) M nadh c 761 R PDHcr Pyruvate dehydrogenase (dihydrolipoamide M dhlam c + M nad c )−−−−* M h c + M lpam c + dehydrogenase) reversible M nadh c 762 R PDIMAS PDIM A synthesis (Mycobacterium Tubercu- 2 M h c + M phthiocerol c +

rdcdby Produced losis) 2 M tamocta c −→ 2 M h2o c + M pdima c 763 R PDIMAT pdima translocase M pdima c −→ M pdima e 764 R PDX5PO pyridoxine 5’-phosphate oxidase M o2 c+M pdx5p c )−−−−* M h2o2 c+M pydx5p c 765 R PEAMNO Phenethylamine oxidase M h2o c + M o2 c + M peamn c −→ M h2o2 c + M nh4 c + M pacald c SBML 766 R PEPCK re phosphoenolpyruvate carboxykinase (GTP) M gtp c + M oaa c )−−−−* M co2 c + M gdp c +

2 M pep c L A T + −−* + + E 767 R PERD Erythronate 4-phosphate (4per) dehydroge- M 4per c M nad c )−− M h c M nadh c X nase M ohpb c 768 R PFK phosphofructokinase M atp c + M f6p c −→ M adp c + M fdp c + M h c 769 R PFL pyruvate formate lyase M coa c + M pyr c −→ M accoa c + M for c 770 R PGAMT phosphoglucosamine mutase M gam1p c )−−−−* M gam6p c 771 R PGCD phosphoglycerate dehydrogenase M 3pg c + M nad c −→ M 3php c + M h c + M nadh c 772 R PGI glucose-6-phosphate isomerase M g6p c )−−−−* M f6p c 773 R PGK phosphoglycerate kinase M 3pg c + M atp c )−−−−* M 13dpg c + M adp c 774 R PGL 6-phosphogluconolactonase M 6pgl c + M h2o c −→ M 6pgc c + M h c 775 R PGLS methoxy fucose rhamnose rhamnose phenol 4 M amet c + M frrppdima c −→ 4 M ahcys c + phthiocerol dimycocerosate synthesis 4 M h c + M mfrrppdima c o N¯ Id Name Reaction Equation SBO 776 R PGLYCP Phosphoglycolate phosphatase M 2pglyc c + M h2o c −→ M glyclt c + M pi c 777 R PGM phosphoglycerate mutase M 2pg c )−−−−* M 3pg c 778 R PGMT phosphoglucomutase M g1p c )−−−−* M g6p c 779 R PGPP160 phosphatidylglycerol phosphate phosphatase M h2o c + M pgp160 c −→ M pg160 c + M pi c (n-C16:0) 780 R PGPP160190 phosphatidylglycerol phosphate phosphatase M h2o c + M pgp160190 c −→ M pg160190 c + (C16:0, C19:0) M pi c 781 R PGPP190 phosphatidylglycerol phosphate phosphatase M h2o c + M pgp190 c −→ M pg190 c + M pi c (C19:0)

rdcdby Produced 782 R PGPPT3 phospho-N-glycolylmuramoyl-pentapeptide- M udcpp c + M uggmda c −→ M ugggmda c + transferase (meso-2,6-diaminopimelate) M ump c 783 R PGSA160 Phosphatidylglycerol synthase (n-C16:0) M cdpdhdecg c + M glyc3p c −→ M cmp c + M h c + M pgp160 c 784 R PGSA160190 Phosphatidylglycerol synthase (C16:0,C19:0) M cdpc16c19g c + M glyc3p c −→ M cmp c + SBML M h c + M pgp160190 c

2 785 R PGSA190 Phosphatidylglycerol synthase (C19:0) M cdpc19c19g c + M glyc3p c −→ M cmp c + L A T + E M h c M pgp190 c X 786 R PHDCATA transacylase M ACP c + M phdcacoa c )−−−−* M coa c + M phdcaACP c 787 R PHDCAt phenol palmitic acid via diffusion (extracellu- M phdca e )−−−−* M phdca c lar) 788 R PHETA1 phenylalanine transaminase M akg c+M phe DASH L c )−−−−* M glu DASH L c+ M phpyr c 789 R PHEt2r L-phenylalanine reversible transport via pro- M h e + M phe DASH L e )−−−−* M h c + ton symport M phe DASH L c 790 R PHTHCLR1 phthiocol reductase (NAD) M nad c + M phthclh2 c )−−−−* M h c + M nadh c + M phthcl c 791 R PHTHCLR2 phthiocol reductase (NAD) M nadp c + M phthclh2 c )−−−−* M h c + 95 M nadph c + M phthcl c 96 o N¯ Id Name Reaction Equation SBO 792 R PHTHCLS phthiocol synthesis M h c + M mndn c + M nadph c + M o2 c −→ M h2o c + M nadp c + M phthcl c 793 R PHTHDLS phthiodolone synthesis M h c + M prephth c −→ M co2 c + M phthdl c 794 R PHTHDLS2 phenolphthiodolone synthesis M h c+M prepphth c −→ M co2 c+M pphthdl c 795 R PHTHS phthiocerol synthesis M amet c + M nadph c + M phthdl c −→ M ahcys c + M nadp c + M phthiocerol c 796 R PHTHS2 phenolphthiocerol synthesis M amet c + M nadph c + M pphthdl c −→ M ahcys c + M nadp c +

rdcdby Produced M pphthiocerol c 797 R PHTO phthiocol oxygenase 2 M o2 c + M phthclh2 c −→ 2 M h c + 2 M o2s c + M phthcl c 798 R PHYCBOXL L-Phenylalanine carboxy-lyase M h c + M phe DASH L c −→ M co2 c + M peamn c SBML 799 R PIabc phosphate transport via ABC system M atp c + M h2o c + M pi e −→ M adp c +

2 M h c + 2 M pi c L A

T −−*

E 800 R PIt Inorganic phosphate exchange, diffusion M pi c )−− M pi e X 801 R PLCD phospholipase C M h2o c + M ptd1ino160 c −→ M 12dgr160 c + M h c + M mi1p DASH D c 802 R PLIPA1E160 Phospholipase A1 (phos- M h2o c + M pe160 c −→ M 2agpe160 c + phatidylethanolamine, n-C16:0) M h c + M hdca c 803 R PLIPA1E180 Phospholipase A1 (phos- M h2o c + M pe180 c −→ M 2agpe180 c + phatidylethanolamine, n-C18:0) M h c + M ocdca c 804 R PMANM phosphomannomutase M man1p c )−−−−* M man6p c 805 R PMDPHT pyrimidine phosphatase M 5aprbu c + M h2o c −→ M 4r5au c + M pi c 806 R PMPK phosphomethylpyrimidine kinase M 4ampm c + M atp c −→ M 2mahmp c + M adp c 807 R PNCDC pantothenoylcysteine decarboxylase M h c + M ptcys c −→ M co2 c + M ptth c o N¯ Id Name Reaction Equation SBO 808 R PNTK pantothenate kinase M atp c + M pnto DASH R c −→ M 4ppan c + M adp c + M h c 809 R PPA inorganic diphosphatase M h2o c + M ppi c −→ M h c + 2 M pi c 810 R PPAtr Propionate transport, diffusion M ppa e )−−−−* M ppa c 811 R PPBNGS porphobilinogen synthase 2 M 5aop c −→ 2 M h2o c + M h c + M ppbng c 812 R PPCDC phosphopantothenoylcysteine decarboxylase M 4ppcys c + M h c −→ M co2 c + M pan4p c 813 R PPCKr phosphoenolpyruvate carboxykinase M atp c + M oaa c )−−−−* M adp c + M co2 c + M pep c 814 R PPCOAC Propionyl-CoA carboxylase M atp c + M hco3 c + M ppcoa c −→ M adp c +

rdcdby Produced M h c + M mmcoa DASH S c + M pi c 815 R PPCSCT Propanoyl-CoA: succinate CoA-transferase M ppcoa c + M succ c −→ M ppa c + M succoa c 816 R PPDIMAS PPDIM synthesis (Mycobacterium Tubercu- 2 M h c + M pphthiocerol c + losis) 2 M tamocta c −→ 2 M h2o c + M ppdima c 817 R PPDIMAT ppdima translocase M ppdima c −→ M ppdima e SBML 818 R PPDK Pyruvate,phosphate dikinase. M atp c + M pi c + M pyr c −→ M amp c +

2 M h c + M pep c + M ppi c L A T + −−* + E 819 R PPGKr Polyphosphate glucokinase reversible M glc DASH D c M pi c )−− M g6p c X M h2o c 820 R PPK2 polyphosphate kinase M atp c + M ppi c −→ M adp c + M pppi c 821 R PPNCL phosphopantothenate-cysteine ligase M 4ppan c + M ctp c + M cys DASH L c −→ M 4ppcys c + M cdp c + M h c + M pi c 822 R PPNCL2 phosphopantothenate-cysteine ligase M 4ppan c + M ctp c + M cys DASH L c −→ M 4ppcys c + M cmp c + M h c + M ppi c 823 R PPNCL3 phosphopantothenate-cysteine ligase M 4ppan c + M atp c + M cys DASH L c −→ M 4ppcys c + M amp c + M h c + M ppi c 97 98 o N¯ Id Name Reaction Equation SBO 824 R PPND prephenate dehydrogenase M nad c + M pphn c −→ M 34hpp c + M co2 c + M nadh c 825 R PPNDH prephenate dehydratase M h c + M pphn c −→ M co2 c + M h2o c + M phpyr c 826 R PPPGO protoporphyrinogen oxidase (aerobic) 1 ·5 M o2 c + M pppg9 c −→ 3 M h2o c + M ppp9 c 827 R PPTGS Peptidoglycan subunit synthesis M uaagmda c −→ M h c + M peptido EC c + M udcpdp c 828 R PPTGS TB1 Peptidoglycan subunit synthesis M uaaAgla c −→ M h c + M peptido TB1 c +

rdcdby Produced M udcpdp c 829 R PPTGS TB2 Peptidoglycan subunit synthesis M uaaGgla c −→ M h c + M peptido TB2 c + M udcpdp c 830 R PRAGSr phosphoribosylglycinamide synthase M atp c + M gly c + M pram c )−−−−* M adp c + M gar c + M h c + M pi c SBML 831 R PRAIS phosphoribosylaminoimidazole synthase M atp c + M fpram c −→ M adp c + M air c +

2 2 M h c + M pi c L A T −→ E 832 R PRAIi phosphoribosylanthranilate isomerase (irre- M pran c M 2cpr5p c X versible) 833 R PRAMPC phosphoribosyl-AMP cyclohydrolase M h2o c + M prbamp c −→ M prfp c 834 R PRASCS phosphoribosylaminoimidazolesuccinocarboxamideM 5aizc c + M asp DASH L c + synthase M atp c )−−−−* M 25aics c + M adp c + M h c + M pi c 835 R PRATPP phosphoribosyl-ATP pyrophosphatase M h2o c + M prbatp c −→ M h c + M ppi c + M prbamp c 836 R PRDX Peroxidase (multiple substrates) M h2o2 c + M meoh c −→ M fald c + 2 M h2o c 837 R PREPHACPH fatty-acyl-ACP hydrolase M h2o c + M prephthACP c −→ M ACP c + M h c + M prephth c 838 R PREPPACPH fatty-acyl-ACP hydrolase M h2o c + M prepphthACP c −→ M ACP c + M h c + M prepphth c o N¯ Id Name Reaction Equation SBO 839 R PREPTHS phthiocerol precursor synthesis M arachACP c + 14 M h c + 2 M malcoa c + 2 M mmcoa DASH S c + 10 M nadph c −→ 2 M co2 c + 4 M coa c + 5 M h2o c + 10 M nadp c + M prephthACP c 840 R PREPTHS2 phenolic phthiocerol precursor synthesis 14 M h c + 2 M malcoa c + 2 M mmcoa DASH S c + 10 M nadph c + M phdcaACP c −→ 2 M co2 c + 4 M coa c + 5 M h2o c + 10 M nadp c + M prepphthACP c 841 R PREPTTA phthiocerol precursor ACP transacylase M ACP c + M prephthcoa c )−−−−* M coa c +

rdcdby Produced M prephthACP c 842 R PRFGS phosphoribosylformylglycinamidine syn- M atp c + M fgam c + M gln DASH L c + thase M h2o c −→ M adp c + M fpram c + M glu DASH L c + M h c + M pi c 843 R PRMICIi 1-(5-phosphoribosyl)-5-[(5- M prfp c −→ M prlp c SBML phosphoribosylamino)methylideneamino)imidazole-

2 4-carboxamide isomerase (irreversible) L A T + −→ + E 844 R PROD2 Proline dehydrogenase M fad c M pro DASH L c M 1pyr5c c X M fadh2 c + M h c 845 R PROabc L-proline transport via ABC system M atp c + M h2o c + M pro DASH L e −→ M adp c + M h c + M pi c + M pro DASH L c 846 R PROt2r L-proline reversible transport via proton sym- M h e + M pro DASH L e )−−−−* M h c + port M pro DASH L c 847 R PRPPS phosphoribosylpyrophosphate synthetase M atp c + M r5p c )−−−−* M amp c + M h c + M prpp c 848 R PSCVT 3-phosphoshikimate 1- M pep c + M skm5p c )−−−−* M 3psme c + M pi c carboxyvinyltransferase 849 R PSD160 Phosphatidylserine decarboxylase (n-C16:0) M h c + M ps160 c −→ M co2 c + M pe160 c 99 850 R PSD180 Phosphatidylserine decarboxylase (n-C18:0) M h c + M ps180 c −→ M co2 c + M pe180 c 100 o N¯ Id Name Reaction Equation SBO 851 R PSERT phosphoserine transaminase M 3php c + M glu DASH L c −→ M akg c + M pser DASH L c 852 R PSP L phosphoserine phosphatase (L-serine) M h2o c + M pser DASH L c −→ M pi c + M ser DASH L c 853 R PSSA160 Phosphatidylserine syntase (n-C16:0) M cdpdhdecg c+M ser DASH L c −→ M cmp c+ M h c + M ps160 c 854 R PSSA180 Phosphatidylserine syntase (n-C18:0) M cdpdodecg c+M ser DASH L c −→ M cmp c+ M h c + M ps180 c 855 R PTAr phosphotransacetylase M accoa c + M pi c )−−−−* M actp c + M coa c

rdcdby Produced 856 R PTPATi pantetheine-phosphate adenylyltransferase M atp c + M h c + M pan4p c −→ M dpcoa c + M ppi c 857 R PUNP1 purine-nucleoside phosphorylase (Adeno- M adn c + M pi c )−−−−* M ade c + M r1p c sine) 858 R PUNP2 purine-nucleoside phosphorylase (De- M dad DASH 2 c + M pi c )−−−−* M 2dr1p c + SBML oxyadenosine) M ade c

2 859 R PUNP3 purine-nucleoside phosphorylase (Guano- M gsn c + M pi c )−−−−* M gua c + M r1p c L A T

E sine) X 860 R PUNP4 purine-nucleoside phosphorylase (De- M dgsn c + M pi c )−−−−* M 2dr1p c + M gua c oxyguanosine) 861 R PUNP5 purine-nucleoside phosphorylase (Inosine) M ins c + M pi c )−−−−* M hxan c + M r1p c 862 R PUNP6 purine-nucleoside phosphorylase (Deoxyino- M din c + M pi c )−−−−* M 2dr1p c + M hxan c sine) 863 R PUNP7 purine-nucleoside phosphorylase (Xantho- M pi c + M xtsn c )−−−−* M r1p c + M xan c sine) 864 R PYAM5PO pyridoxamine 5’-phosphate oxidase M h2o c+M o2 c+M pyam5p c −→ M h2o2 c+ M nh4 c + M pydx5p c 865 R PYDXNO pyridoxine oxidase M o2 c + M pydxn c )−−−−* M h2o2 c + M pydx c 866 R PYDXO pyridoxal oxidase 2 M h2o c + M nh4 c + 0 ·5 M o2 c + M pydx c )−−−−* 2 M h2o2 c + M pydam c o N¯ Id Name Reaction Equation SBO 867 R PYK pyruvate kinase M adp c + M h c + M pep c −→ M atp c + M pyr c 868 R PYRDC pyruvate decarboxylase M h c + M pyr c −→ M acald c + M co2 c 869 R PYRt2r pyruvate reversible transport via proton sym- M h e + M pyr e )−−−−* M h c + M pyr c port 870 R QRr Quinone reductase M h c + M nadph c + M q c )−−−−* M nadp c + M qh2 c 871 R QULNS quinolinate synthase M dhap c + M iasp c −→ 2 M h2o c + M pi c + M quln c

rdcdby Produced 872 R R05217 Precorrin 3A + Oxygen <=> Precorrin 3B M h c + 0 ·5 M o2 c + M pre3a c −→ M pre3b c 873 R R05219 Precorrin 5 <=> Precorrin 6X M amet c + M h2o c + M pre5 c −→ M ac c + M ahcys c + M h c + M pre6a c 874 R R05224 Hydrogenobyrinate <=> Hydrogenobyrinate 2 M atp c + 2 M gln DASH L c + M h2o c + a,c diamide M hgbyr c −→ 2 M adp c + 2 M glu DASH L c + SBML M h c + M hgbam c + M ppi c

2 875 R RBFK riboﬂavin kinase M atp c + M ribﬂv c −→ M adp c + M fmn c + L A T

E M h c X 876 R RBFSa riboflavin synthase M 4r5au c + M db4p c −→ M dmlz c + 2 M h2o c + M pi c 877 R RBFSb riboflavin synthase 2 M dmlz c −→ M 4r5au c + M ribflv c 878 R RBK ribokinase M atp c + M rib DASH D c −→ M adp c + M h c + M r5p c 879 R RBK Dr D-ribulokinase (reversible) M atp c + M rbl DASH D c )−−−−* M adp c + M h c + M ru5p DASH D c 880 R RBK L1r L-ribulokinase (L-ribulose) (reversible) M atp c + M rbl DASH L c )−−−−* M adp c + M h c + M ru5p DASH L c 881 R RIBabc D-ribose transport via ABC system M atp c + M h2o c + M rib DASH D e −→ M adp c + M h c + 101 M pi c + M rib DASH D c 102 o N¯ Id Name Reaction Equation SBO 882 R RNDR1 ribonucleoside-diphosphate reductase (ADP) M adp c + M trdrd c −→ M dadp c + M h2o c + M trdox c 883 R RNDR2 ribonucleoside-diphosphate reductase (GDP) M gdp c + M trdrd c −→ M dgdp c + M h2o c + M trdox c 884 R RNDR3 ribonucleoside-diphosphate reductase (CDP) M cdp c + M trdrd c −→ M dcdp c + M h2o c + M trdox c 885 R RNDR4 ribonucleoside-diphosphate reductase (UDP) M trdrd c + M udp c −→ M dudp c + M h2o c + M trdox c 886 R RNTR4 ribonucleoside-triphosphate reductase (UTP) M trdrd c + M utp c −→ M dutp c + M h2o c +

rdcdby Produced M trdox c 887 R RPE ribulose 5-phosphate 3-epimerase M ru5p DASH D c )−−−−* M xu5p DASH D c 888 R RPI ribose-5-phosphate isomerase M r5p c )−−−−* M ru5p DASH D c 889 R RPPDIMAS rhamnose phenol phthiocerol dimycocerosate M dtdprmn c + M ppdima c −→ M dtdp c + synthesis M h c + M rppdima c SBML 890 R RRPPDIMAS rhamnose rhamnose phenol phthiocerol M dtdprmn c + M rppdima c −→ M dtdp c +

2 dimycocerosate synthesis M h c + M rrppdima c L A T + −→ + E 891 R RZ5PP alpha-ribazole 5-phosphate phosphatase M 5prdmbz c M h2o c M pi c M rdmbzi c X 892 R SADH Succinylarginine dihydrolase 2 M h2o c + 2 M h c + M sucarg c −→ M co2 c + 2 M nh4 c + M sucorn c 893 R SADT sulfate adenylyltransferase M atp c + M h c + M so4 c −→ M aps c + M ppi c 894 R SADT2 Sulfate adenyltransferase M atp c + M gtp c + M h2o c + M so4 c −→ M aps c + M gdp c + M pi c + M ppi c 895 R SALCS salicylate synthase M chor c −→ M pyr c + M salc c 896 R SDPDS succinyl-diaminopimelate desuccinylase M h2o c+M sl26da c −→ M 26dap DASH LL c+ M succ c 897 R SDPTA succinyldiaminopimelate transaminase M akg c + M sl26da c )−−−−* M glu DASH L c + M sl2a6o c o N¯ Id Name Reaction Equation SBO 898 R SELCYSLY selenocysteine lyase M dtt c + M selcys c −→ M ala DASH L c + M dttOX c + M h c + M seln c 899 R SERAT serine O-acetyltransferase M accoa c + M ser DASH L c )−−−−* M acser c + M coa c 900 R SERD D D-serine deaminase M ser DASH D c −→ M nh4 c + M pyr c 901 R SERD L L-serine deaminase M ser DASH L c −→ M nh4 c + M pyr c 902 R SERt2r L-serine reversible transport via proton sym- M h e + M ser DASH L e )−−−−* M h c + port M ser DASH L c 903 R SGDS Succinylglutamate desuccinylase M h2o c + M sucglu c −→ M glu DASH L c +

rdcdby Produced M succ c 904 R SGSAD Succinylglutamic semialdehyde dehydroge- M h2o c + M nad c + M sucgsa c −→ 2 M h c + nase M nadh c + M sucglu c 905 R SHCHCS 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- M ichor c+M sucsal c −→ M 2shchc c+M pyr c carboxylate synthase SBML 906 R SHCHCS2 2-succinyl-6-hydroxy-2,4-cyclohexadiene 1- M ichor c + M ssaltpp c −→ M 2shchc c +

2 carboxylate synthase M pyr c + M thmpp c L A T + −→ + + E 907 R SHCHD2 sirohydrochlorin dehydrogenase (NAD) M dscl c M nad c M h c M nadh c X M scl c 908 R SHCHD3 sirohydrochlorin dehydrogenase (NAD) M nad c + M pre2 c −→ M h c + M nadh c + M scl2 c 909 R SHCHF sirohydrochlorin ferrochelatase M fe2 c + M scl c −→ 3 M h c + M sheme c 910 R SHCHF2 sirohydrochlorin ferrochelatase M fe2 c + M scl2 c −→ 2 M h c + M sheme c 911 R SHCHF3 sirohydrochlorin ferrochelatase (mycobactin) M fmcbtt c + M scl c −→ 3 M h c + M mcbtt c + M sheme c 912 R SHK3Dr shikimate dehydrogenase M 3dhsk c + M h c + M nadph c )−−−−* M nadp c + M skm c 913 R SHKK shikimate kinase M atp c + M skm c −→ M adp c + M h c + M skm5p c 103 104 o N¯ Id Name Reaction Equation SBO 914 R SHSL1r O-succinylhomoserine lyase reversible M cys DASH L c + M suchms c )−−−−* M cyst DASH L c + M h c + M succ c 915 R SHSL4r O-succinylhomoserine lyase (elimination), M h2o c + M suchms c )−−−−* M 2obut c + M h c + reversible M nh4 c + M succ c 916 R SKMt2 shikimate transport in via proton symport M h e + M skm e )−−−−* M h c + M skm c 917 R SOTA Succinylornithine transaminase M akg c + M sucorn c −→ M glu DASH L c + M sucgsa c 918 R SPMS spermidine synthase M ametam c + M ptrc c −→ M 5mta c + M h c +

rdcdby Produced M spmd c 919 R SPODM superoxide dismutase 2 M h c + 2 M o2s c −→ M h2o2 c + M o2 c 920 R SSALx succinate-semialdehyde dehydrogenase M h2o c + M nad c + M sucsal c −→ 2 M h c + (NAD) M nadh c + M succ c 921 R SSALy succinate-semialdehyde dehydrogenase M h2o c + M nadp c + M sucsal c −→ 2 M h c + SBML (NADP) M nadph c + M succ c

2 922 R SUCBZL o-succinylbenzoate-CoA ligase M atp c + M coa c + M sucbz c −→ M amp c + L A T + E M ppi c M sbzcoa c X 923 R SUCBZS O-succinylbenzoate-CoA synthase M 2shchc c −→ M h2o c + M sucbz c 924 R SUCCt2r succinate transport via proton symport M h e + M succ e )−−−−* M h c + M succ c 925 R SUCD1i succinate dehydrogenase M fad c + M succ c −→ M fadh2 c + M fum c 926 R SUCOAS succinyl-CoA synthetase (ADP-forming) M atp c + M coa c + M succ c )−−−−* M adp c + M pi c + M succoa c 927 R SULR sulﬁte reductase (NADPH2) 3 M h2o c + M h2s c + 3 M nadp c )−−−−* 5 M h c + 3 M nadph c + M so3 c 928 R SULabc sulfate transport via ABC system M atp c + M h2o c + M so4 e −→ M adp c + M h c + M pi c + M so4 c 929 R TALA transaldolase M g3p c + M s7p c )−−−−* M e4p c + M f6p c 930 R TARTD L(+)-tartrate dehydratase M tartr DASH L c −→ M h2o c + M oaa c o N¯ Id Name Reaction Equation SBO 931 R TARTRt7 Tartrate/succinate antiporter M succ c + M tartr DASH L e )−−−−* M succ e + M tartr DASH L c 932 R TAS tetra-arabinofuranoside synthesis M arab DASH D c + 3 M decda tb c −→ 3 M decd tb c + M tarab DASH D c 933 R TATS tetra-acyl trehalose synthesis 4 M h c + M hdca c + M hpmtria c + 2 M omtta c + M tre c −→ 4 M h2o c + M tat c 934 R TATSO tetra-acyl trehalose sulfate (sulfolipid-1) syn- 4 M h c + M hdca c + M hpmtria c + thesis 2 M omtta c + M tres c −→ 4 M h2o c + M sl1 c

rdcdby Produced 935 R TDMS1 trehalose dimycolate synthesis 2 M h c + M mmycolate c + M mycolate c + M tre c −→ 2 M h2o c + M tdm1 c 936 R TDMS2 trehalose dimycolate synthesis 2 M h c + M mmmycolate c + M mycolate c + M tre c −→ 2 M h2o c + M tdm2 c 937 R TDMS3 trehalose dimycolate synthesis 2 M h c + M mkmycolate c + M mycolate c + SBML M tre c −→ 2 M h2o c + M tdm3 c

2 938 R TDMS4 trehalose dimycolate synthesis 2 M h c + M kmycolate c + M mycolate c + L A T −→ + E M tre c 2 M h2o c M tdm4 c X 939 R TDPDRE dTDP-4-dehydrorhamnose 3,5-epimerase M dtdp4d6dg c −→ M dtdp4d6dm c 940 R TDPDRR dTDP-4-dehydrorhamnose reductase M dtdp4d6dm c + M h c + M nadph c −→ M dtdprmn c + M nadp c 941 R TDPGDH dTDPglucose 4,6-dehydratase M dtdpglu c −→ M dtdp4d6dg c + M h2o c 942 R THD1 NAD(P) transhydrogenase (B-speciﬁc) M nad c + M nadph c )−−−−* M nadh c + M nadp c 943 R THDPS tetrahydrodipicolinate succinylase M h2o c + M succoa c + M thdp c −→ M coa c + M sl2a6o c 944 R THFGLUS Tetrahydrofolate:L-glutamate gamma-ligase M atp c + M glu DASH L c + (ADP-forming) M thf c )−−−−* M adp c + M h c + M pi c + M thfglu c 945 R THMDP thiamin diphosphatase 2 M h2o c + M thmpp c −→ M h c + 2 M pi c + 105 M thm c 106 o N¯ Id Name Reaction Equation SBO 946 R THRD Lr L-threonine deaminse reversible M thr DASH L c )−−−−* M 2obut c + M nh4 c 947 R THRS threonine synthase M h2o c + M phom c −→ M pi c + M thr DASH L c 948 R THRt2r L-threonine reversible transport via proton M h e + M thr DASH L e )−−−−* M h c + symport M thr DASH L c 949 R THSFST Thiosulfate Sulfurtransferase M cyan c + M tsul c )−−−−* M h c + M so3 c + M tcynt c 950 R THZPSN thiazole phosphate synthesis M atp c + M cys DASH L c + M dxyl5p c + M tyr DASH L c −→ M 4hba c + M 4mpetz c +

rdcdby Produced M ala DASH L c + M amp c + M co2 c + M h2o c + M h c + M ppi c 951 R THZSN thiazole synthesis from xylulose M cys DASH L c + M dxyl c + M tyr DASH L c −→ M 4hba c + M 4mhetz c + M co2 c + M h2o c + M h c + M nh4 c + M pyr c SBML 952 R TKT1 transketolase M r5p c + M xu5p DASH D c )−−−−* M g3p c +

2 M s7p c L A T + −−* + E 953 R TKT2 transketolase M e4p c M xu5p DASH D c )−− M f6p c X M g3p c 954 R TMDK1 thymidine kinase (ATP:thymidine) M atp c + M thymd c −→ M adp c + M dtmp c + M h c 955 R TMDPP thymidine phosphorylase M pi c + M thymd c )−−−−* M 2dr1p c + M thym c 956 R TMDS thymidylate synthase M dump c + M mlthf c −→ M dhf c + M dtmp c 957 R TMHAS1 trehalose dimycolate synthesis M tdm1 c + M tdm2 c + M tre c −→ 2 M h2o c + M tmha1 c 958 R TMHAS2 trehalose dimycolate synthesis M tdm1 c + M tdm3 c + M tre c −→ 2 M h2o c + M tmha2 c 959 R TMHAS3 trehalose dimycolate synthesis M tdm1 c + M tdm4 c + M tre c −→ 2 M h2o c + M tmha3 c o N¯ Id Name Reaction Equation SBO 960 R TMHAS4 trehalose dimycolate synthesis M tdm2 c + M tdm3 c + M tre c −→ 2 M h2o c + M tmha4 c 961 R TMHAS5 trehalose dimycolate synthesis M tdm2 c + M tdm4 c + M tre c −→ 2 M h2o c + M tmha5 c 962 R TMHAS6 trehalose dimycolate synthesis M tdm3 c + M tdm4 c + M tre c −→ 2 M h2o c + M tmha6 c 963 R TMN thiaminase M h2o c + M thm c −→ M 4ahmmp c + M 4mhetz c + M h c 964 R TMPKr thiamine-phosphate kinase M atp c + M thmmp c )−−−−* M adp c + M thmpp c

rdcdby Produced 965 R TMPPP thiamine-phosphate diphosphorylase M 2mahmp c + M 4mpetz c + M h c −→ M ppi c + M thmmp c 966 R TPI triose-phosphate isomerase M dhap c )−−−−* M g3p c 967 R TRDR thioredoxin reductase (NADPH) M h c + M nadph c + M trdox c −→ M nadp c + M trdrd c SBML 968 R TRE6PP trehalose-phosphatase M h2o c + M tre6p c −→ M pi c + M tre c

2 969 R TRE6PS alpha,alpha-trehalose-phosphate synthase M g6p c + M udpg c −→ M h c + M tre6p c + L A T

E (UDP-forming) M udp c X 970 R TRESULT trehalose sulfotransferase M paps c + M tre c −→ M h c + M pap c + M tres c 971 R TREabc trehalose transport via ABC system M atp c + M h2o c + M tre e −→ M adp c + M h c + M pi c + M tre c 972 R TRIATS tri-acyl trehalose sulfonation 3 M h c + 2 M ocdca c + M tmlgnc c + M tre c −→ 3 M h2o c + M triat c 973 R TRPS1 tryptophan synthase (indoleglycerol phos- M 3ig3p c + M ser DASH L c −→ M g3p c + phate) M h2o c + M trp DASH L c 974 R TRPS2 tryptophan synthase (indole) M indole c + M ser DASH L c −→ M h2o c + M trp DASH L c 975 R TRPS3 tryptophan synthase (indoleglycerol phos- M 3ig3p c −→ M g3p c + M indole c 107 phate) 108 o N¯ Id Name Reaction Equation SBO 976 R TRPTA tryptophan transaminase M akg c+M trp DASH L c )−−−−* M glu DASH L c+ M indpyr c 977 R TRPt2r L-tryptophan reversible transport via proton M h e + M trp DASH L e )−−−−* M h c + symport M trp DASH L c 978 R TSULabc thiosulfate transport via ABC system M atp c + M h2o c + M tsul e −→ M adp c + M h c + M pi c + M tsul c 979 R TTDCAt2 Tetradecanoate transport via proton symport M h e + M ttdca e −→ M h c + M ttdca c 980 R TYRTA tyrosine transaminase M akg c + M tyr DASH L c )−−−−* M 34hpp c + M glu DASH L c

rdcdby Produced 981 R TYRt2r L-tyrosine reversible transport via proton M h e + M tyr DASH L e )−−−−* M h c + symport M tyr DASH L c 982 R UAAGDS UDP-N-acetylmuramoyl-L-alanyl-D- M 26dap DASH M c + M atp c + glutamyl-meso-2,6-diaminopimelate syn- M uamag c −→ M adp c + M h c + M pi c + thetase M ugmd c SBML 983 R UAAGLS1 UDP-N-acetylmuramoyl-L-alanyl-D- M atp c + M lys DASH L c +

2 glutamate-lysine synthetase (alpha- M uamag c −→ M adp c + M h c + M pi c + L A T

E glutamate) M uAgl c X 984 R UAAGLS2 UDP-N-acetylmuramoyl-L-alanyl-D- M atp c + M lys DASH L c + glutamyl-L-lysine synthetase (gamma- M uamag c −→ M adp c + M h c + M pi c + glutamate) M uGgl c 985 R UAGCVT UDP-N-acetylglucosamine 1- M pep c + M uacgam c −→ M pi c + M uaccg c carboxyvinyltransferase 986 R UAGDP UDP-N-acetylglucosamine diphosphorylase M acgam1p c + M h c + M utp c −→ M ppi c + M uacgam c 987 R UAGPT1 UDP-N-acetylglucosamine- M uaAgla c + M uacgam c −→ M h c + N-acetylmuramyl- M uaaAgla c + M udp c (pentapeptide)pyrophosphoryl-undecaprenol N-acetylglucosamine transferase o N¯ Id Name Reaction Equation SBO 988 R UAGPT2 UDP-N-acetylglucosamine- M uaGgla c + M uacgam c −→ M h c + N-acetylmuramyl- M uaaGgla c + M udp c (pentapeptide)pyrophosphoryl-undecaprenol N-acetylglucosamine transferase 989 R UAGPT3 UDP-N-acetylglucosamine- M uacgam c + M uagmda c −→ M h c + N-acetylmuramyl- M uaagmda c + M udp c (pentapeptide)pyrophosphoryl-undecaprenol N-acetylglucosamine transferase 990 R UAMAGS UDP-N-acetylmuramoyl-L-alanyl-D- M atp c + M glu DASH D c +

rdcdby Produced glutamate synthetase M uama c −→ M adp c + M h c + M pi c + M uamag c 991 R UAMAS UDP-N-acetylmuramoyl-L-alanine syn- M ala DASH L c + M atp c + thetase M uamr c −→ M adp c + M h c + M pi c + M uama c SBML 992 R UAMRH UDP-MurNAc Hydroxylase M h c + M nadph c + M o2 c +

2 M uamr c −→ M h2o c + M nadp c + M ugmr c L A T + + −→ + E 993 R UAPGR UDP-N-acetylenolpyruvoylglucosamine M h c M nadph c M uaccg c M nadp c X reductase M uamr c 994 R UDCPDP undecaprenyl-diphosphatase M h2o c + M udcpdp c −→ M h c + M pi c + M udcpp c 995 R UDCPDPS Undecaprenyl diphosphate synthase M frdp c + 8 M ipdp c −→ 8 M ppi c + M udcpdp c 996 R UDPDPS undecaprenyl-diphosphate synthase M decdp c + M ipdp c −→ M ppi c + M udcpdp c 997 R UDPDPS2 undecaprenyl-diphosphate synthase M decdp tb c + M ipdp c −→ M ppi c + M udcpdp c 998 R UDPG4E UDPglucose 4-epimerase M udpg c )−−−−* M udpgal c 999 R UDPGALM UDPgalactopyranose mutase M udpgal c −→ M udpgalfur c 1000 R UDPGD UDPglucose 6-dehydrogenase M h2o c + 2 M nad c + M udpg c −→ 3 M h c + 109 2 M nadh c + M udpglcur c 110 o N¯ Id Name Reaction Equation SBO 1001 R UGAGDS UDP-N-glycolylmuramoyl-L-alanyl-D- M 26dap DASH M c + M atp c + glutamyl-meso-2,6-diaminopimelate syn- M ugmag c −→ M adp c + M h c + M pi c + thetase M uggmd c 1002 R UGGPT3 UDP-N-glycolylglucosamine- M uacgam c + M ugggmda c −→ M h c + N-acetylmuramyl- M udp c + M ugagmda c (pentapeptide)pyrophosphoryl-undecaprenol N-acetylglucosamine transferase 1003 R UGLDDS1 UDP-N-acetylmuramoyl-L-alanyl-D- M alaala c + M atp c + M uAgl c −→ M adp c + glutamyl-L-lysyl-D-alanyl-D-alanine syn- M pi c + M uAgla c

rdcdby Produced thetase (alpha-glutamate) 1004 R UGLDDS2 UDP-N-acetylmuramoyl-L-alanyl-D- M alaala c + M atp c + M uGgl c −→ M adp c + glutamyl-L-lysyl-D-alanyl-D-alanine syn- M pi c + M uGgla c thetase (gamma-glutamate) 1005 R UGMAGS UDP-N-glycolylmuramoyl-L-alanyl-D- M atp c + M glu DASH D c + SBML glutamate synthetase M ugma c −→ M adp c + M h c + M pi c +

2 M ugmag c L A T + + E 1006 R UGMAS UDP-N-glycolylmuramoyl-L-alanine syn- M ala DASH L c M atp c X thetase M ugmr c −→ M adp c + M h c + M pi c + M ugma c 1007 R UGMDDS UDP-N-acetylmuramoyl-L-alanyl-D- M alaala c + M atp c + M ugmd c −→ M adp c + glutamyl-meso-2,6-diaminopimeloyl-D- M h c + M pi c + M ugmda c alanyl-D-alanine synthetase 1008 R UGMDDS2 UDP-N-glycolylmuramoyl-L-alanyl-D- M alaala c+M atp c+M uggmd c −→ M adp c+ glutamyl-meso-2,6-diaminopimeloyl-D- M h c + M pi c + M uggmda c alanyl-D-alanine synthetase 1009 R UMPK UMP kinase M atp c + M ump c )−−−−* M adp c + M udp c 1010 R UPP3MT uroporphyrinogen methyltransferase 2 M amet c + M uppg3 c −→ 2 M ahcys c + M dscl c + M h c 1011 R UPP3S uroporphyrinogen-III synthase M hmbil c −→ M h2o c + M uppg3 c o N¯ Id Name Reaction Equation SBO 1012 R UPPDC1 uroporphyrinogen decarboxylase (uropor- 4 M h c + M uppg3 c −→ 4 M co2 c + phyrinogen III) M cpppg3 c 1013 R UPPDC2 uroporphyrinogen decarboxylase (uropor- 4 M h c + M uppg1 c −→ 4 M co2 c + phyrinogen I) M cpppg1 c 1014 R UPPRT uracil phosphoribosyltransferase M prpp c + M ura c −→ M ppi c + M ump c 1015 R UREA urease M h2o c + 2 M h c + M urea c −→ M co2 c + 2 M nh4 c 1016 R URIDK1 uridylate kinase (UMP) M atp c + M ump c −→ M adp c + M udp c 1017 R URIDK2r uridylate kinase (dUMP) M atp c + M dump c )−−−−* M adp c + M dudp c

rdcdby Produced 1018 R URIK2 uridine kinase (GTP:Uridine) M gtp c + M uri c −→ M gdp c + M h c + M ump c 1019 R VALTA valine transaminase M akg c + M val DASH L c )−−−−* M 3mob c + M glu DASH L c 1020 R VALt2r L-valine reversible transport via proton sym- M h e + M val DASH L e )−−−−* M h c + SBML port M val DASH L c

2 1021 R XPPT xanthine phosphoribosyltransferase M prpp c + M xan c −→ M ppi c + M xmp c L A T + −→ + E 1022 R XYLK xylulokinase M atp c M xylu DASH D c M adp c X M h c + M xu5p DASH D c 1023 R XYLabc D-xylose transport via ABC system M atp c + M h2o c + M xyl DASH D e −→ M adp c + M h c + M pi c + M xyl DASH D c 1024 R YUMPS yUMP synthetase M r5p c + M ura c )−−−−* M h2o c + M psd5p c 111 112 o N¯ Id Name Reaction Equation SBO 1025 R biomass Mtb- biomass composition for Mycobacterium tu- 0 ·001681 M Ac1PIM1 c + 9 60atp berculosis (v 0.1) - 60 atp 0 ·001488 M Ac1PIM2 c + 0 ·001335 M Ac1PIM3 c + 0 ·001211 M Ac1PIM4 c + 0 ·001274 M Ac2PIM2 c + 0 ·002076 M PIM1 c + 0 ·00179 M PIM2 c + 0 ·001573 M PIM3 c + 0 ·001403 M PIM4 c + 0 ·001266 M PIM5 c + 0 ·001154 M PIM6 c + 0 ·230181 M acgam1p c +

rdcdby Produced 0 ·405957 M ala DASH L c + 0 ·139026 M amp c + 7.31 · 10−4M arabinanagalfragund c + 0 ·015676 M arach c + 0 ·120416 M arg DASH L c + SBML 0 ·047699 M asn DASH L c +

2 0 ·120308 M asp DASH L c + L A T + · + E 60 M atp c 0 005859 M clpn160190 c X 0 ·250951 M cmp c + 0 ·022 M cys DASH L c + 0 ·003492 M damp c + 0 ·006663 M dcmp c + 0 ·006659 M dgmp c + 0 ·003653 M dtmp c + 0 ·001498 M fcmcbtt c + 0 ·055474 M gal c + 0 ·163152 M glc DASH D c + 0 ·05812 M gln DASH L c + 0 ·090007 M glu DASH L c + 0 ·335808 M gly c + 0 ·025359 M glyc c + 0 ·243651 M gmp c + 60 M h2o c + 0 ·235152 M hdca c + 0 ·01094 M hdcea c + 0 ·058352 M hexc c + 0 ·040617 M his DASH L c + 0 ·087731 M ile DASH L c + 0 ·003338 M kmycolate c + 0 ·204706 M leu DASH L c + 0 ·03909 M lys DASH L c + 0 ·095065 M man c + 0 ·00784 M mbhn c + 0 ·001402 M mcbts c + 0 ·034889 M met DASH L c + 0 ·001184 M mfrrppdima c + 0 ·003291 M mkmycolate c + 0 ·003365 M mmmycolate c + 0 ·095802 M mocdca c + 0 ·011003 M mycolate c + 0 ·034837 M ocdca c + 0 ·009849 M ocdcea c + 0 ·006798 M pa160190 c + 0 ·00724 M pa160 c + 0 ·006407 M pa190190 c + 0 ·001251 M pat c + 2.73 · 10−4M pdima c + 0 ·004061 M pe160 c + 0 ·01885 M peptido TB1 c + 0 ·01885 M peptido TB2 c + 0 ·00613 M pg160190 c + 0 ·006487 M pg160 c + 0 ·00581 M pg190 c + 0 ·006453 M phdca c + 0 ·048102 M phe DASH L c + 2.63 · 10−4M ppdima c + 0 ·138034 M pro DASH L c + 0 ·021723 M rib DASH D c + 0 ·143397 M ser DASH L c + 0 ·001137 M sl1 c + 0 ·001176 M tat c + 0 ·135712 M thr DASH L c + 0 ·001106 M tmha1 c + 0 ·0011 M tmha2 c + 0 ·001104 M tmha3 c + 0 ·001097 M tmha4 c + 0 ·006491 M tre6p c + 0 ·00797 M tre c + 0 ·006474 M tres c + 0 ·020124 M trp DASH L c + 0 ·012193 M ttdca c + 0 ·031756 M tyr DASH L c + 0 ·001008 M uaaAgla c + 0 ·001008 M uaaGgla c + 9.86 · 10−4M uaagmda c + 0 ·002793 M uamr c + 9.77 · 10−4M ugagmda c + 0 ·131604 M ump c + 0 ·205827 M val DASH L c −→ 60 M adp c + 60 M h c + 60 M pi c o N¯ Id Name Reaction Equation SBO rdcdby Produced

SBML 2 L A T E X 113 6.1 Reaction R 2AGPEAT160 This is an irreversible reaction of three reactants forming three products.

Name 2-acyl-glycerophospho-ethanolamine acyltransferase (n-C16:0)

Reaction equation M 2agpe160 c + M atp c + M hdca c −→ M amp c + M pe160 c + M ppi c (1)

Reactants

Table 6: Properties of each reactant. Id Name SBO M 2agpe160 c 2-Acyl-sn-glycero-3-phosphoethanolamine (n-C16:0) M atp c ATP M hdca c Hexadecanoate (n-C16:0)

Products

Table 7: Properties of each product. Id Name SBO M amp c AMP M pe160 c phosphatidylethanolamine (dihexadecanoyl, n-C16:0) M ppi c Diphosphate

Kinetic Law

v1 = not speciﬁed (2)

6.2 Reaction R 2AGPEAT180 This is an irreversible reaction of three reactants forming three products.

Name 2-acyl-glycerophospho-ethanolamine acyltransferase (n-C18:0)

Reaction equation M 2agpe180 c + M atp c + M ocdca c −→ M amp c + M pe180 c + M ppi c (3)

Reactants

114 Produced by SBML2LATEX Table 8: Properties of each reactant. Id Name SBO M 2agpe180 c 2-Acyl-sn-glycero-3-phosphoethanolamine (n-C18:0) M atp c ATP M ocdca c octadecanoate (n-C18:0)

Products

Table 9: Properties of each product. Id Name SBO M amp c AMP M pe180 c phosphatidylethanolamine (dioctadecanoyl, n-C18:0) M ppi c Diphosphate

Kinetic Law

v2 = not speciﬁed (4)

6.3 Reaction R 4HTHRS This is an irreversible reaction of two reactants forming two products.

Name 4-Hydroxy-L-threonine synthase

Reaction equation M h2o c + M phthr c −→ M 4hthr c + M pi c (5)

Reactants

Table 10: Properties of each reactant. Id Name SBO M h2o c H2O M phthr c O-Phospho-4-hydroxy-L-threonine

Products

Produced by SBML2LATEX 115 Table 11: Properties of each product. Id Name SBO M 4hthr c 4-Hydroxy-L-threonine M pi c Phosphate

Kinetic Law

v3 = not speciﬁed (6)

6.4 Reaction R 5DGLCNR This is a reversible reaction of three reactants forming two products.

Name 5-dehydro-D-gluconate reductase

Reaction equation M 5dglcn c + M h c + M nadph c )−−−−* M glcn c + M nadp c (7)

Reactants

Table 12: Properties of each reactant. Id Name SBO M 5dglcn c 5-Dehydro-D-gluconate M h c H+ M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

Products

Table 13: Properties of each product. Id Name SBO M glcn c D-Gluconate M nadp c Nicotinamide adenine dinucleotide phosphate

Kinetic Law

v4 = not speciﬁed (8)

116 Produced by SBML2LATEX 6.5 Reaction R AACPS10 This is an irreversible reaction of three reactants forming three products.

Name acyl-[acyl-carrier-protein] synthetase (tuberculostearic acid)

Reaction equation M ACP c + M atp c + M mocdca c −→ M amp c + M mstrACP c + M ppi c (9)

Reactants

Table 14: Properties of each reactant. Id Name SBO M ACP c acyl carrier protein M atp c ATP M mocdca c 10-methylstearic acid

Products

Table 15: Properties of each product. Id Name SBO M amp c AMP M mstrACP c 10methyl stearyoyl-ACP M ppi c Diphosphate

Kinetic Law

v5 = not speciﬁed (10)

6.6 Reaction R AACPS11 This is an irreversible reaction of three reactants forming three products.

Name acyl-[acyl-carrier-protein] synthetase

Reaction equation M 4hbz c + M ACP c + M atp c −→ M 4hbzACP c + M amp c + M ppi c (11)

Reactants

Produced by SBML2LATEX 117 Table 16: Properties of each reactant. Id Name SBO M 4hbz c 4-Hydroxybenzoate M ACP c acyl carrier protein M atp c ATP

Products

Table 17: Properties of each product. Id Name SBO M 4hbzACP c 4-hydroxybenzoyl ACP M amp c AMP M ppi c Diphosphate

Kinetic Law

v6 = not speciﬁed (12)

6.7 Reaction R AACPS3 This is an irreversible reaction of three reactants forming three products.

Name acyl-[acyl-carrier-protein] synthetase (n-C16:0)

Reaction equation M ACP c + M atp c + M hdca c −→ M amp c + M palmACP c + M ppi c (13)

Reactants

Table 18: Properties of each reactant. Id Name SBO M ACP c acyl carrier protein M atp c ATP M hdca c Hexadecanoate (n-C16:0)

Products

118 Produced by SBML2LATEX Table 19: Properties of each product. Id Name SBO M amp c AMP M palmACP c Palmitoyl-ACP (n-C16:0ACP) M ppi c Diphosphate

Kinetic Law

v7 = not speciﬁed (14)

6.8 Reaction R ABTA This is an irreversible reaction of two reactants forming two products.

Name 4-aminobutyrate transaminase

Reaction equation M 4abut c + M akg c −→ M glu DASH L c + M sucsal c (15)

Reactants

Table 20: Properties of each reactant. Id Name SBO M 4abut c 4-Aminobutanoate M akg c 2-Oxoglutarate

Products

Table 21: Properties of each product. Id Name SBO M glu DASH L c L-Glutamate M sucsal c Succinic semialdehyde

Kinetic Law

v8 = not speciﬁed (16)

Produced by SBML2LATEX 119 6.9 Reaction R ACACCT This is an irreversible reaction of two reactants forming two products.

Name acetyl-CoA:acetoacetyl-CoA transferase

Reaction equation M acac c + M accoa c −→ M aacoa c + M ac c (17)

Reactants

Table 22: Properties of each reactant. Id Name SBO M acac c Acetoacetate M accoa c Acetyl-CoA

Products

Table 23: Properties of each product. Id Name SBO M aacoa c Acetoacetyl-CoA M ac c Acetate

Kinetic Law

v9 = not speciﬁed (18)

6.10 Reaction R ACACT1r This is a reversible reaction of one reactant forming two products.

Name acetyl-CoA C-acetyltransferase

Reaction equation 2M accoa c )−−−−* M aacoa c + M coa c (19)

Reactant

120 Produced by SBML2LATEX Table 24: Properties of each reactant. Id Name SBO M accoa c Acetyl-CoA

Products

Table 25: Properties of each product. Id Name SBO M aacoa c Acetoacetyl-CoA M coa c Coenzyme A

Kinetic Law

v10 = not speciﬁed (20)

6.11 Reaction R ACALDi This is an irreversible reaction of three reactants forming three products.

Name acetaldehyde dehydrogenase (acetylating)

Reaction equation M acald c + M coa c + M nad c −→ M accoa c + M h c + M nadh c (21)

Reactants

Table 26: Properties of each reactant. Id Name SBO M acald c Acetaldehyde M coa c Coenzyme A M nad c Nicotinamide adenine dinucleotide

Products

Table 27: Properties of each product. Id Name SBO M accoa c Acetyl-CoA

Produced by SBML2LATEX 121 Id Name SBO M h c H+ M nadh c Nicotinamide adenine dinucleotide - reduced

Kinetic Law

v11 = not speciﬁed (22)

6.12 Reaction R ACBIPGT This is an irreversible reaction of three reactants forming two products.

Name Adenosyl cobinamide phosphate guanyltransferase

Reaction equation M adocbip c + M gtp c + M h c −→ M agdpcbi c + M ppi c (23)

Reactants

Table 28: Properties of each reactant. Id Name SBO M adocbip c Adenosyl cobinamide phosphate M gtp c GTP M h c H+

Products

Table 29: Properties of each product. Id Name SBO M agdpcbi c Adenosine-GDP-cobinamide M ppi c Diphosphate

Kinetic Law

v12 = not speciﬁed (24)

6.13 Reaction R ACCC This is an irreversible reaction of two reactants forming two products.

122 Produced by SBML2LATEX Name Acyl-CoA Carboxylase

Reaction equation M co2 c + M hexccoa c −→ M chexccoa c + M h2o c (25)

Reactants

Table 30: Properties of each reactant. Id Name SBO M co2 c CO2 M hexccoa c Hexacosanoyl-CoA (n-C26:0CoA)

Products

Table 31: Properties of each product. Id Name SBO M chexccoa c carboxy hexacosanoyl-CoA M h2o c H2O

Kinetic Law

v13 = not speciﬁed (26)

6.14 Reaction R ACCOACr This is a reversible reaction of three reactants forming four products.

Name acetyl-CoA carboxylase, reversible reaction

Reaction equation M accoa c + M atp c + M hco3 c )−−−−* M adp c + M h c + M malcoa c + M pi c (27)

Reactants

Table 32: Properties of each reactant. Id Name SBO M accoa c Acetyl-CoA

Produced by SBML2LATEX 123 Id Name SBO M atp c ATP M hco3 c Bicarbonate

Products

Table 33: Properties of each product. Id Name SBO M adp c ADP M h c H+ M malcoa c Malonyl-CoA M pi c Phosphate

Kinetic Law

v14 = not speciﬁed (28)

6.15 Reaction R ACChex This is an irreversible reaction of three reactants forming two products.

Name Hexanoic Acid CoA Ligase

Reaction equation M coa c + M h c + M hexc c −→ M h2o c + M hexccoa c (29)

Reactants

Table 34: Properties of each reactant. Id Name SBO M coa c Coenzyme A M h c H+ M hexc c hexacosanoate (n-C26:0)

Products

124 Produced by SBML2LATEX Table 35: Properties of each product. Id Name SBO M h2o c H2O M hexccoa c Hexacosanoyl-CoA (n-C26:0CoA)

Kinetic Law

v15 = not speciﬁed (30)

6.16 Reaction R ACGAMPM This is a reversible reaction of one reactant forming one product.

Name phosphoacetylglucosamine mutase

Reaction equation M acgam6p c )−−−−* M acgam1p c (31)

Reactant

Table 36: Properties of each reactant. Id Name SBO M acgam6p c N-Acetyl-D-glucosamine 6-phosphate

Product

Table 37: Properties of each product. Id Name SBO M acgam1p c N-Acetyl-D-glucosamine 1-phosphate

Kinetic Law

v16 = not speciﬁed (32)

6.17 Reaction R ACGAMT

This is an irreversible reaction of two reactants forming two products.

Produced by SBML2LATEX 125 Name UDP-N-acetylglucosamine:undecaprenylphosphate N-acetylglucosamine -1-phosphate transferase

Reaction equation M uacgam c + M udcpp c −→ M ump c + M unaga c (33)

Reactants

Table 38: Properties of each reactant. Id Name SBO M uacgam c UDP-N-acetyl-D-glucosamine M udcpp c Undecaprenyl phosphate

Products

Table 39: Properties of each product. Id Name SBO M ump c UMP M unaga c Undecaprenyl diphospho N-acetyl-glucosamine

Kinetic Law

v17 = not speciﬁed (34)

6.18 Reaction R ACGK This is an irreversible reaction of two reactants forming two products.

Name acetylglutamate kinase

Reaction equation M acglu c + M atp c −→ M acg5p c + M adp c (35)

Reactants

126 Produced by SBML2LATEX Table 40: Properties of each reactant. Id Name SBO M acglu c N-Acetyl-L-glutamate M atp c ATP

Products

Table 41: Properties of each product. Id Name SBO M acg5p c N-Acetyl-L-glutamyl 5-phosphate M adp c ADP

Kinetic Law

v18 = not speciﬁed (36)

6.19 Reaction R ACGS This is an irreversible reaction of two reactants forming three products.

Name N-acetylglutamate synthase

Reaction equation M accoa c + M glu DASH L c −→ M acglu c + M coa c + M h c (37)

Reactants

Table 42: Properties of each reactant. Id Name SBO M accoa c Acetyl-CoA M glu DASH L c L-Glutamate

Products

Table 43: Properties of each product. Id Name SBO M acglu c N-Acetyl-L-glutamate

Produced by SBML2LATEX 127 Id Name SBO M coa c Coenzyme A M h c H+

Kinetic Law

v19 = not speciﬁed (38)

6.20 Reaction R ACHBS This is an irreversible reaction of three reactants forming two products.

Name 2-aceto-2-hydroxybutanoate synthase

Reaction equation M 2obut c + M h c + M pyr c −→ M 2ahbut c + M co2 c (39)

Reactants

Table 44: Properties of each reactant. Id Name SBO M 2obut c 2-Oxobutanoate M h c H+ M pyr c Pyruvate

Products

Table 45: Properties of each product. Id Name SBO M 2ahbut c (S)-2-Aceto-2-hydroxybutanoate M co2 c CO2

Kinetic Law

v20 = not speciﬁed (40)

6.21 Reaction R ACKr This is a reversible reaction of two reactants forming two products.

128 Produced by SBML2LATEX Name acetate kinase

Reaction equation M ac c + M atp c )−−−−* M actp c + M adp c (41)

Reactants

Table 46: Properties of each reactant. Id Name SBO M ac c Acetate M atp c ATP

Products

Table 47: Properties of each product. Id Name SBO M actp c Acetyl phosphate M adp c ADP

Kinetic Law

v21 = not speciﬁed (42)

6.22 Reaction R ACLS This is an irreversible reaction of two reactants forming two products.

Name acetolactate synthase

Reaction equation M h c + 2M pyr c −→ M alac DASH S c + M co2 c (43)

Reactants

Table 48: Properties of each reactant. Id Name SBO M h c H+ M pyr c Pyruvate

Produced by SBML2LATEX 129 Products

Table 49: Properties of each product. Id Name SBO M alac DASH S c (S)-2-Acetolactate M co2 c CO2

Kinetic Law

v22 = not speciﬁed (44)

6.23 Reaction R ACODA This is an irreversible reaction of two reactants forming two products.

Name acetylornithine deacetylase

Reaction equation M acorn c + M h2o c −→ M ac c + M orn c (45)

Reactants

Table 50: Properties of each reactant. Id Name SBO M acorn c N2-Acetyl-L-ornithine M h2o c H2O

Products

Table 51: Properties of each product. Id Name SBO M ac c Acetate M orn c Ornithine

Kinetic Law

v23 = not speciﬁed (46)

130 Produced by SBML2LATEX 6.24 Reaction R ACONT This is a reversible reaction of one reactant forming one product.

Name aconitase

Reaction equation M cit c )−−−−* M icit c (47)

Reactant

Table 52: Properties of each reactant. Id Name SBO M cit c Citrate

Product

Table 53: Properties of each product. Id Name SBO M icit c Isocitrate

Kinetic Law

v24 = not speciﬁed (48)

6.25 Reaction R ACOTA This is a reversible reaction of two reactants forming two products.

Name acetylornithine transaminase

Reaction equation M acorn c + M akg c )−−−−* M acg5sa c + M glu DASH L c (49)

Reactants

Produced by SBML2LATEX 131 Table 54: Properties of each reactant. Id Name SBO M acorn c N2-Acetyl-L-ornithine M akg c 2-Oxoglutarate

Products

Table 55: Properties of each product. Id Name SBO M acg5sa c N-Acetyl-L-glutamate 5-semialdehyde M glu DASH L c L-Glutamate

Kinetic Law

v25 = not speciﬁed (50)

6.26 Reaction R ACP1 FMN This is an irreversible reaction of two reactants forming two products.

Name acid phosphatase (FMN)

Reaction equation M fmn c + M h2o c −→ M pi c + M ribﬂv c (51)

Reactants

Table 56: Properties of each reactant. Id Name SBO M fmn c FMN M h2o c H2O

Products

Table 57: Properties of each product. Id Name SBO M pi c Phosphate

132 Produced by SBML2LATEX Id Name SBO M ribflv c Riboﬂavin

Kinetic Law

v26 = not speciﬁed (52)

6.27 Reaction R ACPS1 This is an irreversible reaction of two reactants forming three products.

Name acyl-carrier protein synthase

Reaction equation M apoACP c + M coa c −→ M ACP c + M h c + M pap c (53)

Reactants

Table 58: Properties of each reactant. Id Name SBO M apoACP c apoprotein [acyl carrier protein] M coa c Coenzyme A

Products

Table 59: Properties of each product. Id Name SBO M ACP c acyl carrier protein M h c H+ M pap c Adenosine 3’,5’-bisphosphate

Kinetic Law

v27 = not speciﬁed (54)

6.28 Reaction R ACS This is an irreversible reaction of three reactants forming three products. Name acetyl-CoA synthetase

Produced by SBML2LATEX 133 Reaction equation M ac c + M atp c + M coa c −→ M accoa c + M amp c + M ppi c (55)

Reactants

Table 60: Properties of each reactant. Id Name SBO M ac c Acetate M atp c ATP M coa c Coenzyme A

Products

Table 61: Properties of each product. Id Name SBO M accoa c Acetyl-CoA M amp c AMP M ppi c Diphosphate

Kinetic Law

v28 = not speciﬁed (56)

6.29 Reaction R ACS2 This is an irreversible reaction of three reactants forming three products.

Name acetyl-CoA synthase (propionate)

Reaction equation M atp c + M coa c + M ppa c −→ M amp c + M ppcoa c + M ppi c (57)

Reactants

Table 62: Properties of each reactant. Id Name SBO M atp c ATP

134 Produced by SBML2LATEX Id Name SBO M coa c Coenzyme A M ppa c Propionate (n-C3:0)

Products

Table 63: Properties of each product. Id Name SBO M amp c AMP M ppcoa c Propanoyl-CoA M ppi c Diphosphate

Kinetic Law

v29 = not speciﬁed (58)

6.30 Reaction R ACYSBMNt This is a reversible reaction of one reactant forming one product.

Name acysbmn transport (mtb)

Reaction equation M acysbmn c )−−−−* M acysbmn e (59)

Reactant

Table 64: Properties of each reactant. Id Name SBO M acysbmn c acetyl-cystine-bimane

Product

Table 65: Properties of each product. Id Name SBO M acysbmn e acetyl-cystine-bimane

Produced by SBML2LATEX 135 Kinetic Law

v30 = not speciﬁed (60)

6.31 Reaction R ADA This is an irreversible reaction of three reactants forming two products.

Name Adenosine deaminase

Reaction equation M adn c + M h2o c + M h c −→ M ins c + M nh4 c (61)

Reactants

Table 66: Properties of each reactant. Id Name SBO M adn c Adenosine M h2o c H2O M h c H+

Products

Table 67: Properties of each product. Id Name SBO M ins c Inosine M nh4 c Ammonium

Kinetic Law

v31 = not speciﬁed (62)

6.32 Reaction R ADCL This is an irreversible reaction of one reactant forming three products.

Name 4-aminobenzoate synthase

Reaction equation M 4adcho c −→ M 4abz c + M h c + M pyr c (63)

136 Produced by SBML2LATEX Reactant

Table 68: Properties of each reactant. Id Name SBO M 4adcho c 4-amino-4-deoxychorismate

Products

Table 69: Properties of each product. Id Name SBO M 4abz c 4-Aminobenzoate M h c H+ M pyr c Pyruvate

Kinetic Law

v32 = not speciﬁed (64)

6.33 Reaction R ADCPS1 This is an irreversible reaction of three reactants forming four products.

Name adenosylcobinamide-phosphate synthase

Reaction equation M adcobhex c + M appl c + M atp c −→ M adocbi c + M adp c + M h c + M pi c (65)

Reactants

Table 70: Properties of each reactant. Id Name SBO M adcobhex c adenosyl-cobyric acid M appl c 1-Aminopropan-2-ol M atp c ATP

Products

Produced by SBML2LATEX 137 Table 71: Properties of each product. Id Name SBO M adocbi c Adenosyl cobinamide M adp c ADP M h c H+ M pi c Phosphate

Kinetic Law

v33 = not speciﬁed (66)

6.34 Reaction R ADCPS2 This is an irreversible reaction of three reactants forming four products.

Name adenosylcobinamide-phosphate synthase

Reaction equation M adcobhex c + M applp c + M atp c −→ M adocbip c + M adp c + M h c + M pi c (67)

Reactants

Table 72: Properties of each reactant. Id Name SBO M adcobhex c adenosyl-cobyric acid M applp c D-1-Aminopropan-2-ol O-phosphate M atp c ATP

Products

Table 73: Properties of each product. Id Name SBO M adocbip c Adenosyl cobinamide phosphate M adp c ADP M h c H+ M pi c Phosphate

138 Produced by SBML2LATEX Kinetic Law

v34 = not speciﬁed (68)

6.35 Reaction R ADCS This is an irreversible reaction of two reactants forming two products.

Name 4-amino-4-deoxychorismate synthase

Reaction equation M chor c + M gln DASH L c −→ M 4adcho c + M glu DASH L c (69)

Reactants

Table 74: Properties of each reactant. Id Name SBO M chor c chorismate M gln DASH L c L-Glutamine

Products

Table 75: Properties of each product. Id Name SBO M 4adcho c 4-amino-4-deoxychorismate M glu DASH L c L-Glutamate

Kinetic Law

v35 = not speciﬁed (70)

6.36 Reaction R ADCYRS This is an irreversible reaction of four reactants forming ﬁve products.

Name adenosylcobyric acid synthase (glutamine-hydrolysing)

Reaction equation M adcobdam c + 4M atp c + 4M gln DASH L c + 4M h2o c −→ M adcobhex c + 4M adp c + 4M glu DASH L c + 4M h c + 4M pi c (71)

Produced by SBML2LATEX 139 Reactants

Table 76: Properties of each reactant. Id Name SBO M adcobdam c Adenosyl cobyrinate diamide M atp c ATP M gln DASH L c L-Glutamine M h2o c H2O

Products

Table 77: Properties of each product. Id Name SBO M adcobhex c adenosyl-cobyric acid M adp c ADP M glu DASH L c L-Glutamate M h c H+ M pi c Phosphate

Kinetic Law

v36 = not speciﬁed (72)

6.37 Reaction R ADK1 This is a reversible reaction of two reactants forming one product.

Name adenylate kinase

Reaction equation M amp c + M atp c )−−−−* 2M adp c (73)

Reactants

Table 78: Properties of each reactant. Id Name SBO M amp c AMP M atp c ATP

140 Produced by SBML2LATEX Product

Table 79: Properties of each product. Id Name SBO M adp c ADP

Kinetic Law

v37 = not speciﬁed (74)

6.38 Reaction R ADK2 This is a reversible reaction of two reactants forming two products.

Name adenylate kinase (Inorganic triphosphate)

Reaction equation M amp c + M pppi c )−−−−* M adp c + M ppi c (75)

Reactants

Table 80: Properties of each reactant. Id Name SBO M amp c AMP M pppi c Inorganic triphosphate

Products

Table 81: Properties of each product. Id Name SBO M adp c ADP M ppi c Diphosphate

Kinetic Law

v38 = not speciﬁed (76)

Produced by SBML2LATEX 141 6.39 Reaction R ADK3 This is a reversible reaction of two reactants forming two products.

Name adentylate kinase (GTP)

Reaction equation M amp c + M gtp c )−−−−* M adp c + M gdp c (77)

Reactants

Table 82: Properties of each reactant. Id Name SBO M amp c AMP M gtp c GTP

Products

Table 83: Properties of each product. Id Name SBO M adp c ADP M gdp c GDP

Kinetic Law

v39 = not speciﬁed (78)

6.40 Reaction R ADK4 This is a reversible reaction of two reactants forming two products.

Name adentylate kinase (ITP)

Reaction equation M amp c + M itp c )−−−−* M adp c + M idp c (79)

Reactants

142 Produced by SBML2LATEX Table 84: Properties of each reactant. Id Name SBO M amp c AMP M itp c ITP

Products

Table 85: Properties of each product. Id Name SBO M adp c ADP M idp c IDP

Kinetic Law

v40 = not speciﬁed (80)

6.41 Reaction R ADMDCr This is a reversible reaction of two reactants forming two products.

Name Adenosylmethionine decarboxylase

Reaction equation M amet c + M h c )−−−−* M ametam c + M co2 c (81)

Reactants

Table 86: Properties of each reactant. Id Name SBO M amet c S-Adenosyl-L-methionine M h c H+

Products

Table 87: Properties of each product. Id Name SBO M ametam c S-Adenosylmethioninamine

Produced by SBML2LATEX 143 Id Name SBO M co2 c CO2

Kinetic Law

v41 = not speciﬁed (82)

6.42 Reaction R ADNCYC This is an irreversible reaction of one reactant forming two products.

Name adenylate cyclase

Reaction equation M atp c −→ M camp c + M ppi c (83)

Reactant

Table 88: Properties of each reactant. Id Name SBO M atp c ATP

Products

Table 89: Properties of each product. Id Name SBO M camp c cAMP M ppi c Diphosphate

Kinetic Law

v42 = not speciﬁed (84)

6.43 Reaction R ADNK1 This is an irreversible reaction of two reactants forming three products.

Name adenosine kinase

144 Produced by SBML2LATEX Reaction equation M adn c + M atp c −→ M adp c + M amp c + M h c (85)

Reactants

Table 90: Properties of each reactant. Id Name SBO M adn c Adenosine M atp c ATP

Products

Table 91: Properties of each product. Id Name SBO M adp c ADP M amp c AMP M h c H+

Kinetic Law

v43 = not speciﬁed (86)

6.44 Reaction R ADNK3 This is an irreversible reaction of two reactants forming three products.

Name adenosine kinase

Reaction equation M adn c + M gtp c −→ M amp c + M gdp c + M h c (87)

Reactants

Table 92: Properties of each reactant. Id Name SBO M adn c Adenosine M gtp c GTP

Produced by SBML2LATEX 145 Products

Table 93: Properties of each product. Id Name SBO M amp c AMP M gdp c GDP M h c H+

Kinetic Law

v44 = not speciﬁed (88)

6.45 Reaction R ADNK4 This is an irreversible reaction of two reactants forming three products.

Name adenosine kinase

Reaction equation M adn c + M dgtp c −→ M amp c + M dgdp c + M h c (89)

Reactants

Table 94: Properties of each reactant. Id Name SBO M adn c Adenosine M dgtp c dGTP

Products

Table 95: Properties of each product. Id Name SBO M amp c AMP M dgdp c dGDP M h c H+

146 Produced by SBML2LATEX Kinetic Law

v45 = not speciﬁed (90)

6.46 Reaction R ADOCBIK This is an irreversible reaction of two reactants forming three products.

Name Adenosyl cobinamide kinase

Reaction equation M adocbi c + M atp c −→ M adocbip c + M adp c + M h c (91)

Reactants

Table 96: Properties of each reactant. Id Name SBO M adocbi c Adenosyl cobinamide M atp c ATP

Products

Table 97: Properties of each product. Id Name SBO M adocbip c Adenosyl cobinamide phosphate M adp c ADP M h c H+

Kinetic Law

v46 = not speciﬁed (92)

6.47 Reaction R ADOCBLS This is an irreversible reaction of two reactants forming three products.

Name Adenosylcobalamin 5’-phosphate synthase

Reaction equation M agdpcbi c + M rdmbzi c −→ M adocbl c + M gmp c + M h c (93)

Produced by SBML2LATEX 147 Reactants

Table 98: Properties of each reactant. Id Name SBO M agdpcbi c Adenosine-GDP-cobinamide M rdmbzi c N1-(alpha-D-ribosyl)-5,6-dimethylbenzimidazole

Products

Table 99: Properties of each product. Id Name SBO M adocbl c Adenosylcobalamin M gmp c GMP M h c H+

Kinetic Law

v47 = not speciﬁed (94)

6.48 Reaction R ADPT This is an irreversible reaction of two reactants forming two products.

Name adenine phosphoribosyltransferase

Reaction equation M ade c + M prpp c −→ M amp c + M ppi c (95)

Reactants

Table 100: Properties of each reactant. Id Name SBO M ade c Adenine M prpp c 5-Phospho-alpha-D-ribose 1-diphosphate

Products

148 Produced by SBML2LATEX Table 101: Properties of each product. Id Name SBO M amp c AMP M ppi c Diphosphate

Kinetic Law

v48 = not speciﬁed (96)

6.49 Reaction R ADSK This is an irreversible reaction of two reactants forming three products.

Name adenylyl-sulfate kinase

Reaction equation M aps c + M atp c −→ M adp c + M h c + M paps c (97)

Reactants

Table 102: Properties of each reactant. Id Name SBO M aps c Adenosine 5’-phosphosulfate M atp c ATP

Products

Table 103: Properties of each product. Id Name SBO M adp c ADP M h c H+ M paps c 3’-Phosphoadenylyl sulfate

Kinetic Law

v49 = not speciﬁed (98)

Produced by SBML2LATEX 149 6.50 Reaction R ADSL1r This is a reversible reaction of one reactant forming two products.

Name adenylsuccinate lyase

Reaction equation M dcamp c )−−−−* M amp c + M fum c (99)

Reactant

Table 104: Properties of each reactant. Id Name SBO M dcamp c N6-(1,2-Dicarboxyethyl)-AMP

Products

Table 105: Properties of each product. Id Name SBO M amp c AMP M fum c Fumarate

Kinetic Law

v50 = not speciﬁed (100)

6.51 Reaction R ADSL2r This is a reversible reaction of one reactant forming two products.

Name adenylosuccinate lyase

Reaction equation M 25aics c )−−−−* M aicar c + M fum c (101)

Reactant

150 Produced by SBML2LATEX Table 106: Properties of each reactant. Id Name SBO M 25aics c (S)-2-[5-Amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido]succinate

Products

Table 107: Properties of each product. Id Name SBO M aicar c 5-Amino-1-(5-Phospho-D-ribosyl)imidazole-4-carboxamide M fum c Fumarate

Kinetic Law

v51 = not speciﬁed (102)

6.52 Reaction R ADSS This is an irreversible reaction of three reactants forming four products.

Name adenylosuccinate synthase

Reaction equation M asp DASH L c + M gtp c + M imp c −→ M dcamp c + M gdp c + 2M h c + M pi c (103)

Reactants

Table 108: Properties of each reactant. Id Name SBO M asp DASH L c L-Aspartate M gtp c GTP M imp c IMP

Products

Produced by SBML2LATEX 151 Table 109: Properties of each product. Id Name SBO M dcamp c N6-(1,2-Dicarboxyethyl)-AMP M gdp c GDP M h c H+ M pi c Phosphate

Kinetic Law

v52 = not speciﬁed (104)

6.53 Reaction R AFE This is an irreversible reaction of two reactants forming two products.

Name arabinofuranosyl extension (M tb)

Reaction equation M agalfragund c + M arabinan c −→ M arabinanagalfragund c + M h2o c (105)

Reactants

Table 110: Properties of each reactant. Id Name SBO M agalfragund c arabinofuranose-galactofuranosyl(30)-rhamanosyl-N-acetylglucosamyl-undecaprenyl diphosphate (M tb) M arabinan c arabinan complex (Mtb)

Products

Table 111: Properties of each product. Id Name SBO M arabinanagalfragund c arabinan-arabinofuranose-galactofuranosyl(30)-rhamanosyl-N-acetylglucosamyl-undecaprenyl diphosphate (M tb) M h2o c H2O

Kinetic Law

v53 = not speciﬁed (106)

152 Produced by SBML2LATEX 6.54 Reaction R AFTA This is an irreversible reaction of two reactants forming two products.

Name arabinofuranosyl transferase (M tb)

Reaction equation M decda tb c + M galfragund c −→ M agalfragund c + M decd tb c (107)

Reactants

Table 112: Properties of each reactant. Id Name SBO M decda tb c decaprenylphosphoryl-beta-D-arabinofuranose M galfragund c galactofuranosyl(30)-rhamanosyl-N-acetylglucosamyl-undecaprenyl diphosphate (M tb)

Products

Table 113: Properties of each product. Id Name SBO M agalfragund c arabinofuranose-galactofuranosyl(30)-rhamanosyl-N-acetylglucosamyl-undecaprenyl diphosphate (M tb) M decd tb c (E,E,E,E,E,E,E,Z,Z) decaprenyl phosphate

Kinetic Law

v54 = not speciﬁed (108)

6.55 Reaction R AGDC This is an irreversible reaction of two reactants forming two products.

Name N-acetylglucosamine-6-phosphate deacetylase

Reaction equation M acgam6p c + M h2o c −→ M ac c + M gam6p c (109)

Reactants

Produced by SBML2LATEX 153 Table 114: Properties of each reactant. Id Name SBO M acgam6p c N-Acetyl-D-glucosamine 6-phosphate M h2o c H2O

Products

Table 115: Properties of each product. Id Name SBO M ac c Acetate M gam6p c D-Glucosamine 6-phosphate

Kinetic Law

v55 = not speciﬁed (110)

6.56 Reaction R AGMT This is an irreversible reaction of two reactants forming two products.

Name agmatinase

Reaction equation M agm c + M h2o c −→ M ptrc c + M urea c (111)

Reactants

Table 116: Properties of each reactant. Id Name SBO M agm c Agmatine M h2o c H2O

Products

Table 117: Properties of each product. Id Name SBO M ptrc c Putrescine

154 Produced by SBML2LATEX Id Name SBO M urea c Urea

Kinetic Law

v56 = not speciﬁed (112)

6.57 Reaction R AGPAT160 This is an irreversible reaction of two reactants forming two products.

Name 1-hexadecanoyl-sn-glycerol 3-phosphate O-acyltransferase (n-C16:0)

Reaction equation M 1hdecg3p c + M palmACP c −→ M ACP c + M pa160 c (113)

Reactants

Table 118: Properties of each reactant. Id Name SBO M 1hdecg3p c 1-hexadecanoyl-sn-glycerol 3-phosphate M palmACP c Palmitoyl-ACP (n-C16:0ACP)

Products

Table 119: Properties of each product. Id Name SBO M ACP c acyl carrier protein M pa160 c 1,2-dihexadecanoyl-sn-glycerol 3-phosphate

Kinetic Law

v57 = not speciﬁed (114)

6.58 Reaction R AGPAT160190 This is an irreversible reaction of two reactants forming two products.

Name 1-hexadecanoyl-sn-glycerol 3-phosphate O-acyltransferase

Produced by SBML2LATEX 155 Reaction equation M 1hdecg3p c + M mstrACP c −→ M ACP c + M pa160190 c (115)

Reactants

Table 120: Properties of each reactant. Id Name SBO M 1hdecg3p c 1-hexadecanoyl-sn-glycerol 3-phosphate M mstrACP c 10methyl stearyoyl-ACP

Products

Table 121: Properties of each product. Id Name SBO M ACP c acyl carrier protein M pa160190 c 1,2-sn-glycerol 3-phosphate

Kinetic Law

v58 = not speciﬁed (116)

6.59 Reaction R AGPAT190 This is an irreversible reaction of two reactants forming two products.

Name 1-hexadecanoyl-sn-glycerol 3-phosphate O-acyltransferase

Reaction equation M 1msg3p c + M mstrACP c −→ M ACP c + M pa190190 c (117)

Reactants

Table 122: Properties of each reactant. Id Name SBO M 1msg3p c 1-Acyl-sn-glycerol 3-phosphate (branched C19:0) M mstrACP c 10methyl stearyoyl-ACP

156 Produced by SBML2LATEX Products

Table 123: Properties of each product. Id Name SBO M ACP c acyl carrier protein M pa190190 c 1,2-sn-glycerol 3-phosphate

Kinetic Law

v59 = not speciﬁed (118)

6.60 Reaction R AGPR This is a reversible reaction of three reactants forming three products.

Name N-acetyl-g-glutamyl-phosphate reductase

Reaction equation M acg5sa c + M nadp c + M pi c )−−−−* M acg5p c + M h c + M nadph c (119)

Reactants

Table 124: Properties of each reactant. Id Name SBO M acg5sa c N-Acetyl-L-glutamate 5-semialdehyde M nadp c Nicotinamide adenine dinucleotide phosphate M pi c Phosphate

Products

Table 125: Properties of each product. Id Name SBO M acg5p c N-Acetyl-L-glutamyl 5-phosphate M h c H+ M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

Produced by SBML2LATEX 157 Kinetic Law

v60 = not speciﬁed (120)

6.61 Reaction R AHC This is a reversible reaction of two reactants forming two products.

Name adenosylhomocysteinase

Reaction equation M ahcys c + M h2o c )−−−−* M adn c + M hcys DASH L c (121)

Reactants

Table 126: Properties of each reactant. Id Name SBO M ahcys c S-Adenosyl-L-homocysteine M h2o c H2O

Products

Table 127: Properties of each product. Id Name SBO M adn c Adenosine M hcys DASH L c L-Homocysteine

Kinetic Law

v61 = not speciﬁed (122)

6.62 Reaction R AHCYSNS This is an irreversible reaction of two reactants forming two products.

Name S-adenosylhomocysteine nucleosidase

Reaction equation M ahcys c + M h2o c −→ M ade c + M rhcys c (123)

158 Produced by SBML2LATEX Reactants

Table 128: Properties of each reactant. Id Name SBO M ahcys c S-Adenosyl-L-homocysteine M h2o c H2O

Products

Table 129: Properties of each product. Id Name SBO M ade c Adenine M rhcys c S-Ribosyl-L-homocysteine

Kinetic Law

v62 = not speciﬁed (124)

6.63 Reaction R AHMMPS This is an irreversible reaction of two reactants forming three products.

Name 4-amino-5-hydroxymethyl-2-methylpyrimidine synthetase

Reaction equation M air c + 2M h c −→ M 4ahmmp c + M gcald c + M pi c (125)

Reactants

Table 130: Properties of each reactant. Id Name SBO M air c 5-amino-1-(5-phospho-D-ribosyl)imidazole M h c H+

Products

Produced by SBML2LATEX 159 Table 131: Properties of each product. Id Name SBO M 4ahmmp c 4-Amino-5-hydroxymethyl-2-methylpyrimidine M gcald c Glycolaldehyde M pi c Phosphate

Kinetic Law

v63 = not speciﬁed (126)

6.64 Reaction R AICART This is a reversible reaction of two reactants forming two products.

Name phosphoribosylaminoimidazolecarboxamide formyltransferase

Reaction equation M 10fthf c + M aicar c )−−−−* M fprica c + M thf c (127)

Reactants

Table 132: Properties of each reactant. Id Name SBO M 10fthf c 10-Formyltetrahydrofolate M aicar c 5-Amino-1-(5-Phospho-D-ribosyl)imidazole-4-carboxamide

Products

Table 133: Properties of each product. Id Name SBO M fprica c 5-Formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide M thf c 5,6,7,8-Tetrahydrofolate

Kinetic Law

v64 = not speciﬁed (128)

160 Produced by SBML2LATEX 6.65 Reaction R AICART2 This is a reversible reaction of three reactants forming three products.

Name phosphoribosylaminoimidazolecarboxamide formyltransferase 2

Reaction equation M aicar c + M atp c + M for c )−−−−* M adp c + M fprica c + M pi c (129)

Reactants

Table 134: Properties of each reactant. Id Name SBO M aicar c 5-Amino-1-(5-Phospho-D-ribosyl)imidazole-4-carboxamide M atp c ATP M for c Formate

Products

Table 135: Properties of each product. Id Name SBO M adp c ADP M fprica c 5-Formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide M pi c Phosphate

Kinetic Law

v65 = not speciﬁed (130)

6.66 Reaction R AIRC2 This is an irreversible reaction of three reactants forming four products.

Name phosphoribosylaminoimidazole carboxylase

Reaction equation M air c + M atp c + M hco3 c −→ M 5caiz c + M adp c + M h c + M pi c (131)

Reactants

Produced by SBML2LATEX 161 Table 136: Properties of each reactant. Id Name SBO M air c 5-amino-1-(5-phospho-D-ribosyl)imidazole M atp c ATP M hco3 c Bicarbonate

Products

Table 137: Properties of each product. Id Name SBO M 5caiz c 5-phosphoribosyl-5-carboxyaminoimidazole M adp c ADP M h c H+ M pi c Phosphate

Kinetic Law

v66 = not speciﬁed (132)

6.67 Reaction R AIRC3 This is a reversible reaction of one reactant forming one product.

Name phosphoribosylaminoimidazole carboxylase (mutase rxn)

Reaction equation M 5aizc c )−−−−* M 5caiz c (133)

Reactant

Table 138: Properties of each reactant. Id Name SBO M 5aizc c 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

Product

162 Produced by SBML2LATEX Table 139: Properties of each product. Id Name SBO M 5caiz c 5-phosphoribosyl-5-carboxyaminoimidazole

Kinetic Law

v67 = not speciﬁed (134)

6.68 Reaction R AIRCr This is a reversible reaction of two reactants forming two products.

Name phosphoribosylaminoimidazole carboxylase

Reaction equation M air c + M co2 c )−−−−* M 5aizc c + M h c (135)

Reactants

Table 140: Properties of each reactant. Id Name SBO M air c 5-amino-1-(5-phospho-D-ribosyl)imidazole M co2 c CO2

Products

Table 141: Properties of each product. Id Name SBO M 5aizc c 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate M h c H+

Kinetic Law

v68 = not speciﬁed (136)

6.69 Reaction R AKGDb This is an irreversible reaction of two reactants forming two products.

Produced by SBML2LATEX 163 Name oxoglutarate dehydrogenase (dihydrolipoamide S-succinyltransferase)

Reaction equation M coa c + M sdhlam c −→ M dhlam c + M succoa c (137)

Reactants

Table 142: Properties of each reactant. Id Name SBO M coa c Coenzyme A M sdhlam c S-Succinyldihydrolipoamide

Products

Table 143: Properties of each product. Id Name SBO M dhlam c Dihydrolipoamide M succoa c Succinyl-CoA

Kinetic Law

v69 = not speciﬁed (138)

6.70 Reaction R ALAALAD This is an irreversible reaction of two reactants forming one product.

Name D-alanine-D-alanine dipeptidase

Reaction equation M alaala c + M h2o c −→ 2M ala DASH D c (139)

Reactants

Table 144: Properties of each reactant. Id Name SBO M alaala c D-Alanyl-D-alanine M h2o c H2O

164 Produced by SBML2LATEX Product

Table 145: Properties of each product. Id Name SBO M ala DASH D c D-Alanine

Kinetic Law

v70 = not speciﬁed (140)

6.71 Reaction R ALAALAr This is a reversible reaction of two reactants forming four products.

Name D-alanine-D-alanine ligase (reversible)

Reaction equation 2M ala DASH D c + M atp c −−)−−* M adp c + M alaala c + M h c + M pi c (141)

Reactants

Table 146: Properties of each reactant. Id Name SBO M ala DASH D c D-Alanine M atp c ATP

Products

Table 147: Properties of each product. Id Name SBO M adp c ADP M alaala c D-Alanyl-D-alanine M h c H+ M pi c Phosphate

Kinetic Law

v71 = not speciﬁed (142)

Produced by SBML2LATEX 165 6.72 Reaction R ALAD L This is an irreversible reaction of three reactants forming four products.

Name L-alanine dehydrogenase

Reaction equation M ala DASH L c + M h2o c + M nad c −→ M h c + M nadh c + M nh4 c + M pyr c (143)

Reactants

Table 148: Properties of each reactant. Id Name SBO M ala DASH L c L-Alanine M h2o c H2O M nad c Nicotinamide adenine dinucleotide

Products

Table 149: Properties of each product. Id Name SBO M h c H+ M nadh c Nicotinamide adenine dinucleotide - reduced M nh4 c Ammonium M pyr c Pyruvate

Kinetic Law

v72 = not speciﬁed (144)

6.73 Reaction R ALAR This is a reversible reaction of one reactant forming one product.

Name alanine racemase

Reaction equation

M ala DASH L c )−−−−* M ala DASH D c (145)

166 Produced by SBML2LATEX Reactant

Table 150: Properties of each reactant. Id Name SBO M ala DASH L c L-Alanine

Product

Table 151: Properties of each product. Id Name SBO M ala DASH D c D-Alanine

Kinetic Law

v73 = not speciﬁed (146)

6.74 Reaction R ALATA L This is a reversible reaction of two reactants forming two products.

Name L-alanine transaminase

Reaction equation M akg c + M ala DASH L c )−−−−* M glu DASH L c + M pyr c (147)

Reactants

Table 152: Properties of each reactant. Id Name SBO M akg c 2-Oxoglutarate M ala DASH L c L-Alanine

Products

Produced by SBML2LATEX 167 Table 153: Properties of each product. Id Name SBO M glu DASH L c L-Glutamate M pyr c Pyruvate

Kinetic Law

v74 = not speciﬁed (148)

6.75 Reaction R ALATRS This is an irreversible reaction of three reactants forming three products.

Name Alanyl-tRNA synthetase

Reaction equation M ala DASH L c + M atp c + M trnaala c −→ M alatrna c + M amp c + M ppi c (149)

Reactants

Table 154: Properties of each reactant. Id Name SBO M ala DASH L c L-Alanine M atp c ATP M trnaala c tRNA(Ala)

Products

Table 155: Properties of each product. Id Name SBO M alatrna c L-Alanyl-tRNA(Ala) M amp c AMP M ppi c Diphosphate

Kinetic Law

v75 = not speciﬁed (150)

168 Produced by SBML2LATEX 6.76 Reaction R ALAt2r This is a reversible reaction of two reactants forming two products.

Name L-alanine reversible transport via proton symport

Reaction equation M ala DASH L e + M h e )−−−−* M ala DASH L c + M h c (151)

Reactants

Table 156: Properties of each reactant. Id Name SBO M ala DASH L e L-Alanine M h e H+

Products

Table 157: Properties of each product. Id Name SBO M ala DASH L c L-Alanine M h c H+

Kinetic Law

v76 = not speciﬁed (152)

6.77 Reaction R ALDD1 This is an irreversible reaction of three reactants forming three products.

Name aldehyde dehydrogenase (formaldehyde, NAD)

Reaction equation M fald c + M h2o c + M nad c −→ M for c + 2M h c + M nadh c (153)

Reactants

Produced by SBML2LATEX 169 Table 158: Properties of each reactant. Id Name SBO M fald c Formaldehyde M h2o c H2O M nad c Nicotinamide adenine dinucleotide

Products

Table 159: Properties of each product. Id Name SBO M for c Formate M h c H+ M nadh c Nicotinamide adenine dinucleotide - reduced

Kinetic Law

v77 = not speciﬁed (154)

6.78 Reaction R ALDD19x This is an irreversible reaction of three reactants forming three products.

Name aldehyde dehydrogenase (phenylacetaldehyde, NAD)

Reaction equation M h2o c + M nad c + M pacald c −→ 2M h c + M nadh c + M pac c (155)

Reactants

Table 160: Properties of each reactant. Id Name SBO M h2o c H2O M nad c Nicotinamide adenine dinucleotide M pacald c Phenylacetaldehyde

Products

170 Produced by SBML2LATEX Table 161: Properties of each product. Id Name SBO M h c H+ M nadh c Nicotinamide adenine dinucleotide - reduced M pac c Phenylacetic acid

Kinetic Law

v78 = not speciﬁed (156)

6.79 Reaction R ALDD2x This is an irreversible reaction of three reactants forming three products.

Name aldehyde dehydrogenase (acetaldehyde, NAD)

Reaction equation M acald c + M h2o c + M nad c −→ M ac c + 2M h c + M nadh c (157)

Reactants

Table 162: Properties of each reactant. Id Name SBO M acald c Acetaldehyde M h2o c H2O M nad c Nicotinamide adenine dinucleotide

Products

Table 163: Properties of each product. Id Name SBO M ac c Acetate M h c H+ M nadh c Nicotinamide adenine dinucleotide - reduced

Kinetic Law

v79 = not speciﬁed (158)

Produced by SBML2LATEX 171 6.80 Reaction R AMAOTr This is a reversible reaction of two reactants forming two products.

Name adenosylmethionine-8-amino-7-oxononanoate transaminase

Reaction equation M 8aonn c + M amet c )−−−−* M amob c + M dann c (159)

Reactants

Table 164: Properties of each reactant. Id Name SBO M 8aonn c 8-Amino-7-oxononanoate M amet c S-Adenosyl-L-methionine

Products

Table 165: Properties of each product. Id Name SBO M amob c S-Adenosyl-4-methylthio-2-oxobutanoate M dann c 7,8-Diaminononanoate

Kinetic Law

v80 = not speciﬁed (160)

6.81 Reaction R AMID4 This is an irreversible reaction of two reactants forming two products.

Name amidase

Reaction equation M ad c + M h2o c −→ M ac c + M nh4 c (161)

Reactants

172 Produced by SBML2LATEX Table 166: Properties of each reactant. Id Name SBO M ad c acetamide M h2o c H2O

Products

Table 167: Properties of each product. Id Name SBO M ac c Acetate M nh4 c Ammonium

Kinetic Law

v81 = not speciﬁed (162)

6.82 Reaction R AMMQT6 This is an irreversible reaction of two reactants forming three products.

Name S-adenosylmethione

Reaction equation M 2dmmq6 c + M amet c −→ M ahcys c + M h c + M mqn6 c (163)

Reactants

Table 168: Properties of each reactant. Id Name SBO M 2dmmq6 c 2-Demethylmenaquinone 6 M amet c S-Adenosyl-L-methionine

Products

Table 169: Properties of each product. Id Name SBO M ahcys c S-Adenosyl-L-homocysteine

Produced by SBML2LATEX 173 Id Name SBO M h c H+ M mqn6 c Menaquinone 6

Kinetic Law

v82 = not speciﬁed (164)

6.83 Reaction R AMMQT8 This is an irreversible reaction of three reactants forming two products.

Name S-adenosylmethione:2-demthylmenaquinone methyltransferase (menaquinone 8)

Reaction equation M 2dmmq8 c + M amet c + M h c −→ M ahcys c + M mql8 c (165)

Reactants

Table 170: Properties of each reactant. Id Name SBO M 2dmmq8 c 2-Demethylmenaquinone 8 M amet c S-Adenosyl-L-methionine M h c H+

Products

Table 171: Properties of each product. Id Name SBO M ahcys c S-Adenosyl-L-homocysteine M mql8 c Menaquinol 8

Kinetic Law

v83 = not speciﬁed (166)

6.84 Reaction R AMMQT8 2 This is an irreversible reaction of two reactants forming three products.

174 Produced by SBML2LATEX Name S-adenosylmethione:2-demethylmenaquinone methyltransferase

Reaction equation M 2dmmq8 c + M amet c −→ M ahcys c + M h c + M mqn8 c (167)

Reactants

Table 172: Properties of each reactant. Id Name SBO M 2dmmq8 c 2-Demethylmenaquinone 8 M amet c S-Adenosyl-L-methionine

Products

Table 173: Properties of each product. Id Name SBO M ahcys c S-Adenosyl-L-homocysteine M h c H+ M mqn8 c Menaquinone 8

Kinetic Law

v84 = not speciﬁed (168)

6.85 Reaction R AMPTASECG This is an irreversible reaction of two reactants forming two products.

Name alanyl aminopeptidase (cys-gly)

Reaction equation M cgly c + M h2o c −→ M cys DASH L c + M gly c (169)

Reactants

Produced by SBML2LATEX 175 Table 174: Properties of each reactant. Id Name SBO M cgly c Cys-Gly M h2o c H2O

Products

Table 175: Properties of each product. Id Name SBO M cys DASH L c L-Cysteine M gly c Glycine

Kinetic Law

v85 = not speciﬁed (170)

6.86 Reaction R ANPRT This is an irreversible reaction of two reactants forming two products.

Name anthranilate phosphoribosyltransferase

Reaction equation M anth c + M prpp c −→ M ppi c + M pran c (171)

Reactants

Table 176: Properties of each reactant. Id Name SBO M anth c Anthranilate M prpp c 5-Phospho-alpha-D-ribose 1-diphosphate

Products

Table 177: Properties of each product. Id Name SBO M ppi c Diphosphate

176 Produced by SBML2LATEX Id Name SBO M pran c N-(5-Phospho-D-ribosyl)anthranilate

Kinetic Law

v86 = not speciﬁed (172)

6.87 Reaction R ANS This is an irreversible reaction of two reactants forming four products.

Name anthranilate synthase

Reaction equation M chor c + M gln DASH L c −→ M anth c + M glu DASH L c + M h c + M pyr c (173)

Reactants

Table 178: Properties of each reactant. Id Name SBO M chor c chorismate M gln DASH L c L-Glutamine

Products

Table 179: Properties of each product. Id Name SBO M anth c Anthranilate M glu DASH L c L-Glutamate M h c H+ M pyr c Pyruvate

Kinetic Law

v87 = not speciﬁed (174)

6.88 Reaction R AOXSr This is a reversible reaction of three reactants forming three products.

Produced by SBML2LATEX 177 Name 8-amino-7-oxononanoate synthase

Reaction equation M ala DASH L c + M h c + M pmcoa c )−−−−* M 8aonn c + M co2 c + M coa c (175)

Reactants

Table 180: Properties of each reactant. Id Name SBO M ala DASH L c L-Alanine M h c H+ M pmcoa c Pimeloyl-CoA

Products

Table 181: Properties of each product. Id Name SBO M 8aonn c 8-Amino-7-oxononanoate M co2 c CO2 M coa c Coenzyme A

Kinetic Law

v88 = not speciﬁed (176)

6.89 Reaction R APATr This is a reversible reaction of two reactants forming two products.

Name B-alanine-pyruvate aminotransferase

Reaction equation M ala DASH B c + M pyr c )−−−−* M ala DASH L c + M msa c (177)

Reactants

178 Produced by SBML2LATEX Table 182: Properties of each reactant. Id Name SBO M ala DASH B c beta-Alanine M pyr c Pyruvate

Products

Table 183: Properties of each product. Id Name SBO M ala DASH L c L-Alanine M msa c Malonate semialdehyde

Kinetic Law

v89 = not speciﬁed (178)

6.90 Reaction R APRAUR This is an irreversible reaction of three reactants forming two products.

Name 5-amino-6-(5-phosphoribosylamino)uracil reductase

Reaction equation M 5apru c + M h c + M nadph c −→ M 5aprbu c + M nadp c (179)

Reactants

Table 184: Properties of each reactant. Id Name SBO M 5apru c 5-Amino-6-(5’-phosphoribosylamino)uracil M h c H+ M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

Products

Produced by SBML2LATEX 179 Table 185: Properties of each product. Id Name SBO M 5aprbu c 5-Amino-6-(5’-phosphoribitylamino)uracil M nadp c Nicotinamide adenine dinucleotide phosphate

Kinetic Law

v90 = not speciﬁed (180)

6.91 Reaction R ARABF This is an irreversible reaction of three reactants forming two products.

Name arabinan complex formation (M tb)

Reaction equation 12M arab DASH D c + 8M mharab DASH D c + 12M tarab DASH D c −→ M arabinan c + 32M h2o c (181)

Reactants

Table 186: Properties of each reactant. Id Name SBO M arab DASH D c D-Arabinose M mharab DASH D c mannose capped hexa arabinofuranoside M tarab DASH D c tetra-arabinofuranoside

Products

Table 187: Properties of each product. Id Name SBO M arabinan c arabinan complex (Mtb) M h2o c H2O

Kinetic Law

v91 = not speciﬁed (182)

180 Produced by SBML2LATEX 6.92 Reaction R ARABI This is a reversible reaction of one reactant forming one product.

Name arabinose isomerase

Reaction equation M arab DASH D c )−−−−* M rbl DASH D c (183)

Reactant

Table 188: Properties of each reactant. Id Name SBO M arab DASH D c D-Arabinose

Product

Table 189: Properties of each product. Id Name SBO M rbl DASH D c D-Ribulose

Kinetic Law

v92 = not speciﬁed (184)

6.93 Reaction R ARACHTA This is a reversible reaction of two reactants forming two products.

Name transacylase

Reaction equation M ACP c + M arachcoa c )−−−−* M arachACP c + M coa c (185)

Reactants

Produced by SBML2LATEX 181 Table 190: Properties of each reactant. Id Name SBO M ACP c acyl carrier protein M arachcoa c arachidyl coenzyme A

Products

Table 191: Properties of each product. Id Name SBO M arachACP c eicosanoyl-ACP (n-C20:0) M coa c Coenzyme A

Kinetic Law

v93 = not speciﬁed (186)

6.94 Reaction R ARAI This is a reversible reaction of one reactant forming one product.

Name L-arabinose isomerase

Reaction equation M arab DASH L c )−−−−* M rbl DASH L c (187)

Reactant

Table 192: Properties of each reactant. Id Name SBO M arab DASH L c L-Arabinose

Product

Table 193: Properties of each product. Id Name SBO M rbl DASH L c L-Ribulose

182 Produced by SBML2LATEX Kinetic Law

v94 = not speciﬁed (188)

6.95 Reaction R ARB Dabc This is an irreversible reaction of three reactants forming four products.

Name L-arabinose transport via ABC system

Reaction equation M arab DASH D e + M atp c + M h2o c −→ M adp c + M arab DASH D c + M h c + M pi c (189)

Reactants

Table 194: Properties of each reactant. Id Name SBO M arab DASH D e D-Arabinose M atp c ATP M h2o c H2O

Products

Table 195: Properties of each product. Id Name SBO M adp c ADP M arab DASH D c D-Arabinose M h c H+ M pi c Phosphate

Kinetic Law

v95 = not speciﬁed (190)

6.96 Reaction R ARBabc This is an irreversible reaction of three reactants forming four products.

Name L-arabinose transport via ABC system

Produced by SBML2LATEX 183 Reaction equation M arab DASH L e + M atp c + M h2o c −→ M adp c + M arab DASH L c + M h c + M pi c (191)

Reactants

Table 196: Properties of each reactant. Id Name SBO M arab DASH L e L-Arabinose M atp c ATP M h2o c H2O

Products

Table 197: Properties of each product. Id Name SBO M adp c ADP M arab DASH L c L-Arabinose M h c H+ M pi c Phosphate

Kinetic Law

v96 = not speciﬁed (192)

6.97 Reaction R ARBt2r This is a reversible reaction of two reactants forming two products.

Name L-arabinose transport via proton symport

Reaction equation M arab DASH L e + M h e )−−−−* M arab DASH L c + M h c (193)

Reactants

184 Produced by SBML2LATEX Table 198: Properties of each reactant. Id Name SBO M arab DASH L e L-Arabinose M h e H+

Products

Table 199: Properties of each product. Id Name SBO M arab DASH L c L-Arabinose M h c H+

Kinetic Law

v97 = not speciﬁed (194)

6.98 Reaction R ARGDC This is an irreversible reaction of two reactants forming two products.

Name arginine decarboxylase

Reaction equation M arg DASH L c + M h c −→ M agm c + M co2 c (195)

Reactants

Table 200: Properties of each reactant. Id Name SBO M arg DASH L c L-Arginine M h c H+

Products

Table 201: Properties of each product. Id Name SBO M agm c Agmatine

Produced by SBML2LATEX 185 Id Name SBO M co2 c CO2

Kinetic Law

v98 = not speciﬁed (196)

6.99 Reaction R ARGDr This is a reversible reaction of two reactants forming two products.

Name arginine deiminase

Reaction equation M arg DASH L c + M h2o c )−−−−* M citr DASH L c + M nh4 c (197)

Reactants

Table 202: Properties of each reactant. Id Name SBO M arg DASH L c L-Arginine M h2o c H2O

Products

Table 203: Properties of each product. Id Name SBO M citr DASH L c L-Citrulline M nh4 c Ammonium

Kinetic Law

v99 = not speciﬁed (198)

6.100 Reaction R ARGSL This is a reversible reaction of one reactant forming two products.

Name argininosuccinate lyase

186 Produced by SBML2LATEX Reaction equation M argsuc c )−−−−* M arg DASH L c + M fum c (199)

Reactant

Table 204: Properties of each reactant. Id Name SBO M argsuc c N(omega)-(L-Arginino)succinate

Products

Table 205: Properties of each product. Id Name SBO M arg DASH L c L-Arginine M fum c Fumarate

Kinetic Law

v100 = not speciﬁed (200)

6.101 Reaction R ARGSS This is an irreversible reaction of three reactants forming four products.

Name argininosuccinate synthase

Reaction equation M asp DASH L c + M atp c + M citr DASH L c −→ M amp c + M argsuc c + M h c + M ppi c (201)

Reactants

Table 206: Properties of each reactant. Id Name SBO M asp DASH L c L-Aspartate M atp c ATP M citr DASH L c L-Citrulline

Produced by SBML2LATEX 187 Products

Table 207: Properties of each product. Id Name SBO M amp c AMP M argsuc c N(omega)-(L-Arginino)succinate M h c H+ M ppi c Diphosphate

Kinetic Law

v101 = not speciﬁed (202)

6.102 Reaction R ARGt5r This is a reversible reaction of one reactant forming one product.

Name L-arginine transport via diffusion

Reaction equation M arg DASH L e )−−−−* M arg DASH L c (203)

Reactant

Table 208: Properties of each reactant. Id Name SBO M arg DASH L e L-Arginine

Product

Table 209: Properties of each product. Id Name SBO M arg DASH L c L-Arginine

Kinetic Law

v102 = not speciﬁed (204)

188 Produced by SBML2LATEX 6.103 Reaction R ARI This is a reversible reaction of one reactant forming one product.

Name arabinose ribose isomerase

Reaction equation M arpp c )−−−−* M prpp c (205)

Reactant

Table 210: Properties of each reactant. Id Name SBO M arpp c 5-phosphoarabinose pyrophosphate

Product

Table 211: Properties of each product. Id Name SBO M prpp c 5-Phospho-alpha-D-ribose 1-diphosphate

Kinetic Law

v103 = not speciﬁed (206)

6.104 Reaction R ASAD This is a reversible reaction of three reactants forming three products.

Name aspartate-semialdehyde dehydrogenase

Reaction equation M aspsa c + M nadp c + M pi c )−−−−* M 4pasp c + M h c + M nadph c (207)

Reactants

Produced by SBML2LATEX 189 Table 212: Properties of each reactant. Id Name SBO M aspsa c L-Aspartate 4-semialdehyde M nadp c Nicotinamide adenine dinucleotide phosphate M pi c Phosphate

Products

Table 213: Properties of each product. Id Name SBO M 4pasp c 4-Phospho-L-aspartate M h c H+ M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

Kinetic Law

v104 = not speciﬁed (208)

6.105 Reaction R ASNN This is an irreversible reaction of two reactants forming two products.

Name L-asparaginase

Reaction equation M asn DASH L c + M h2o c −→ M asp DASH L c + M nh4 c (209)

Reactants

Table 214: Properties of each reactant. Id Name SBO M asn DASH L c L-Asparagine M h2o c H2O

Products

190 Produced by SBML2LATEX Table 215: Properties of each product. Id Name SBO M asp DASH L c L-Aspartate M nh4 c Ammonium

Kinetic Law

v105 = not speciﬁed (210)

6.106 Reaction R ASNS1 This is an irreversible reaction of four reactants forming ﬁve products.

Name asparagine synthase (glutamine-hydrolysing)

Reaction equation M asp DASH L c + M atp c + M gln DASH L c + M h2o c −→ M amp c + M asn DASH L c + M glu DASH L c + M h c + M ppi c (211)

Reactants

Table 216: Properties of each reactant. Id Name SBO M asp DASH L c L-Aspartate M atp c ATP M gln DASH L c L-Glutamine M h2o c H2O

Products

Table 217: Properties of each product. Id Name SBO M amp c AMP M asn DASH L c L-Asparagine M glu DASH L c L-Glutamate M h c H+ M ppi c Diphosphate

Produced by SBML2LATEX 191 Kinetic Law

v106 = not speciﬁed (212)

6.107 Reaction R ASNt2r This is a reversible reaction of two reactants forming two products.

Name L-asparagine reversible transport via proton symport

Reaction equation M asn DASH L e + M h e )−−−−* M asn DASH L c + M h c (213)

Reactants

Table 218: Properties of each reactant. Id Name SBO M asn DASH L e L-Asparagine M h e H+

Products

Table 219: Properties of each product. Id Name SBO M asn DASH L c L-Asparagine M h c H+

Kinetic Law

v107 = not speciﬁed (214)

6.108 Reaction R ASP1DC This is an irreversible reaction of two reactants forming two products.

Name aspartate 1-decarboxylase

Reaction equation M asp DASH L c + M h c −→ M ala DASH B c + M co2 c (215)

192 Produced by SBML2LATEX Reactants

Table 220: Properties of each reactant. Id Name SBO M asp DASH L c L-Aspartate M h c H+

Products

Table 221: Properties of each product. Id Name SBO M ala DASH B c beta-Alanine M co2 c CO2

Kinetic Law

v108 = not speciﬁed (216)

6.109 Reaction R ASPCT This is an irreversible reaction of two reactants forming three products.

Name aspartate carbamoyltransferase

Reaction equation M asp DASH L c + M cbp c −→ M cbasp c + M h c + M pi c (217)

Reactants

Table 222: Properties of each reactant. Id Name SBO M asp DASH L c L-Aspartate M cbp c Carbamoyl phosphate

Products

Produced by SBML2LATEX 193 Table 223: Properties of each product. Id Name SBO M cbasp c N-Carbamoyl-L-aspartate M h c H+ M pi c Phosphate

Kinetic Law

v109 = not speciﬁed (218)

6.110 Reaction R ASPK This is a reversible reaction of two reactants forming two products.

Name aspartate kinase

Reaction equation M asp DASH L c + M atp c )−−−−* M 4pasp c + M adp c (219)

Reactants

Table 224: Properties of each reactant. Id Name SBO M asp DASH L c L-Aspartate M atp c ATP

Products

Table 225: Properties of each product. Id Name SBO M 4pasp c 4-Phospho-L-aspartate M adp c ADP

Kinetic Law

v110 = not speciﬁed (220)

194 Produced by SBML2LATEX 6.111 Reaction R ASPO1 This is an irreversible reaction of three reactants forming three products.

Name L-aspartate oxidase

Reaction equation M asp DASH L c + M h2o c + M o2 c −→ M h2o2 c + M nh4 c + M oaa c (221)

Reactants

Table 226: Properties of each reactant. Id Name SBO M asp DASH L c L-Aspartate M h2o c H2O M o2 c O2

Products

Table 227: Properties of each product. Id Name SBO M h2o2 c Hydrogen peroxide M nh4 c Ammonium M oaa c Oxaloacetate

Kinetic Law

v111 = not speciﬁed (222)

6.112 Reaction R ASPO5 This is an irreversible reaction of two reactants forming three products.

Name L-aspartate oxidase

Reaction equation M asp DASH L c + M fum c −→ M h c + M iasp c + M succ c (223)

Reactants

Produced by SBML2LATEX 195 Table 228: Properties of each reactant. Id Name SBO M asp DASH L c L-Aspartate M fum c Fumarate

Products

Table 229: Properties of each product. Id Name SBO M h c H+ M iasp c Iminoaspartate M succ c Succinate

Kinetic Law

v112 = not speciﬁed (224)

6.113 Reaction R ASPTA This is a reversible reaction of two reactants forming two products.

Name aspartate transaminase

Reaction equation M akg c + M asp DASH L c )−−−−* M glu DASH L c + M oaa c (225)

Reactants

Table 230: Properties of each reactant. Id Name SBO M akg c 2-Oxoglutarate M asp DASH L c L-Aspartate

Products

196 Produced by SBML2LATEX Table 231: Properties of each product. Id Name SBO M glu DASH L c L-Glutamate M oaa c Oxaloacetate

Kinetic Law

v113 = not speciﬁed (226)

6.114 Reaction R ASPt2r This is a reversible reaction of two reactants forming two products.

Name L-aspartate reversible transport via proton symport

Reaction equation M asp DASH L e + M h e )−−−−* M asp DASH L c + M h c (227)

Reactants

Table 232: Properties of each reactant. Id Name SBO M asp DASH L e L-Aspartate M h e H+

Products

Table 233: Properties of each product. Id Name SBO M asp DASH L c L-Aspartate M h c H+

Kinetic Law

v114 = not speciﬁed (228)

6.115 Reaction R AST This is an irreversible reaction of two reactants forming three products.

Produced by SBML2LATEX 197 Name Arginine succinyltransferase

Reaction equation M arg DASH L c + M succoa c −→ M coa c + M h c + M sucarg c (229)

Reactants

Table 234: Properties of each reactant. Id Name SBO M arg DASH L c L-Arginine M succoa c Succinyl-CoA

Products

Table 235: Properties of each product. Id Name SBO M coa c Coenzyme A M h c H+ M sucarg c N2-Succinyl-L-arginine

Kinetic Law

v115 = not speciﬁed (230)

6.116 Reaction R ATPPRT This is an irreversible reaction of two reactants forming two products.

Name ATP phosphoribosyltransferase

Reaction equation M atp c + M prpp c −→ M ppi c + M prbatp c (231)

Reactants

198 Produced by SBML2LATEX Table 236: Properties of each reactant. Id Name SBO M atp c ATP M prpp c 5-Phospho-alpha-D-ribose 1-diphosphate

Products

Table 237: Properties of each product. Id Name SBO M ppi c Diphosphate M prbatp c 1-(5-Phosphoribosyl)-ATP

Kinetic Law

v116 = not speciﬁed (232)

6.117 Reaction R ATPS1 This is an irreversible reaction of three reactants forming three products.

Name H+-exporting ATPase

Reaction equation M atp c + M h2o c + M h c −→ M adp c + 2M h e + M pi c (233)

Reactants

Table 238: Properties of each reactant. Id Name SBO M atp c ATP M h2o c H2O M h c H+

Products

Produced by SBML2LATEX 199 Table 239: Properties of each product. Id Name SBO M adp c ADP M h e H+ M pi c Phosphate

Kinetic Law

v117 = not speciﬁed (234)

6.118 Reaction R ATPS4r This is a reversible reaction of three reactants forming three products.

Name ATP synthase (four protons for one ATP)

Reaction equation M adp c + 4M h e + M pi c )−−−−* M atp c + M h2o c + 3M h c (235)

Reactants

Table 240: Properties of each reactant. Id Name SBO M adp c ADP M h e H+ M pi c Phosphate

Products

Table 241: Properties of each product. Id Name SBO M atp c ATP M h2o c H2O M h c H+

Kinetic Law

v118 = not speciﬁed (236)

200 Produced by SBML2LATEX 6.119 Reaction R BACCL This is an irreversible reaction of three reactants forming two products.

Name biotin-[acetyl-CoA-carboxylase] ligase

Reaction equation M atp c + M btn c + M h c −→ M btamp c + M ppi c (237)

Reactants

Table 242: Properties of each reactant. Id Name SBO M atp c ATP M btn c Biotin M h c H+

Products

Table 243: Properties of each product. Id Name SBO M btamp c Biotinyl-5’-AMP M ppi c Diphosphate

Kinetic Law

v119 = not speciﬁed (238)

6.120 Reaction R BALAt2r This is a reversible reaction of two reactants forming two products.

Name beta-alanine reversible transport via proton symport

Reaction equation M ala DASH B e + M h e )−−−−* M ala DASH B c + M h c (239)

Reactants

Produced by SBML2LATEX 201 Table 244: Properties of each reactant. Id Name SBO M ala DASH B e beta-Alanine M h e H+

Products

Table 245: Properties of each product. Id Name SBO M ala DASH B c beta-Alanine M h c H+

Kinetic Law

v120 = not speciﬁed (240)

6.121 Reaction R BDH This is a reversible reaction of two reactants forming three products.

Name (R)-3-Hydroxybutanoate:NAD+ oxidoreductase

Reaction equation M bhb c + M nad c )−−−−* M acac c + M h c + M nadh c (241)

Reactants

Table 246: Properties of each reactant. Id Name SBO M bhb c (R)-3-Hydroxybutanoate M nad c Nicotinamide adenine dinucleotide

Products

Table 247: Properties of each product. Id Name SBO M acac c Acetoacetate

202 Produced by SBML2LATEX Id Name SBO M h c H+ M nadh c Nicotinamide adenine dinucleotide - reduced

Kinetic Law

v121 = not speciﬁed (242)

6.122 Reaction R BETALDHx This is an irreversible reaction of three reactants forming three products.

Name betaine-aldehyde dehydrogenase

Reaction equation M betald c + M h2o c + M nad c −→ M glyb c + 2M h c + M nadh c (243)

Reactants

Table 248: Properties of each reactant. Id Name SBO M betald c Betaine aldehyde M h2o c H2O M nad c Nicotinamide adenine dinucleotide

Products

Table 249: Properties of each product. Id Name SBO M glyb c Glycine betaine M h c H+ M nadh c Nicotinamide adenine dinucleotide - reduced

Kinetic Law

v122 = not speciﬁed (244)

6.123 Reaction R BMNMSHS This is an irreversible reaction of two reactants forming two products.

Produced by SBML2LATEX 203 Name conjugated mycothiol synthesis

Reaction equation M bmn c + M msh c −→ M bmnmsh c + 2M h c (245)

Reactants

Table 250: Properties of each reactant. Id Name SBO M bmn c bimane M msh c mycothiol (reduced)

Products

Table 251: Properties of each product. Id Name SBO M bmnmsh c bimane conjugated mycothiol (mtb) M h c H+

Kinetic Law

v123 = not speciﬁed (246)

6.124 Reaction R BMNt This is a reversible reaction of one reactant forming one product.

Name bimane transport (diffusion)

Reaction equation M bmn c )−−−−* M bmn e (247)

Reactant

Table 252: Properties of each reactant. Id Name SBO M bmn c bimane

204 Produced by SBML2LATEX Product

Table 253: Properties of each product. Id Name SBO M bmn e bimane

Kinetic Law

v124 = not speciﬁed (248)

6.125 Reaction R BPNT This is an irreversible reaction of two reactants forming two products.

Name 3’,5’-bisphosphate nucleotidase

Reaction equation M h2o c + M pap c −→ M amp c + M pi c (249)

Reactants

Table 254: Properties of each reactant. Id Name SBO M h2o c H2O M pap c Adenosine 3’,5’-bisphosphate

Products

Table 255: Properties of each product. Id Name SBO M amp c AMP M pi c Phosphate

Kinetic Law

v125 = not speciﬁed (250)

Produced by SBML2LATEX 205 6.126 Reaction R BTS2 This is a reversible reaction of two reactants forming three products.

Name biotin synthase (ala-L producing)

Reaction equation M cys DASH L c + M dtbt c −−)−−* M ala DASH L c + M btn c + 2M h c (251)

Reactants

Table 256: Properties of each reactant. Id Name SBO M cys DASH L c L-Cysteine M dtbt c Dethiobiotin

Products

Table 257: Properties of each product. Id Name SBO M ala DASH L c L-Alanine M btn c Biotin M h c H+

Kinetic Law

v126 = not speciﬁed (252)

6.127 Reaction R BTS3r This is a reversible reaction of two reactants forming two products.

Name biotin synthase

Reaction equation M dtbt c + 2M s c )−−−−* M btn c + M h2s c (253)

Reactants

206 Produced by SBML2LATEX Table 258: Properties of each reactant. Id Name SBO M dtbt c Dethiobiotin M s c Sulfur

Products

Table 259: Properties of each product. Id Name SBO M btn c Biotin M h2s c Hydrogen sulﬁde

Kinetic Law

v127 = not speciﬁed (254)

6.128 Reaction R CAATPS This is an irreversible reaction of three reactants forming four products.

Name Ca ATPase

Reaction equation M atp c + 2M ca2 c + M h2o c −→ M adp c + 2M ca2 e + M h e + M pi c (255)

Reactants

Table 260: Properties of each reactant. Id Name SBO M atp c ATP M ca2 c Calcium M h2o c H2O

Products

Produced by SBML2LATEX 207 Table 261: Properties of each product. Id Name SBO M adp c ADP M ca2 e Calcium M h e H+ M pi c Phosphate

Kinetic Law

v128 = not speciﬁed (256)

6.129 Reaction R CAT This is an irreversible reaction of one reactant forming two products.

Name catalase

Reaction equation 2M h2o2 c −→ 2M h2o c + M o2 c (257)

Reactant

Table 262: Properties of each reactant. Id Name SBO M h2o2 c Hydrogen peroxide

Products

Table 263: Properties of each product. Id Name SBO M h2o c H2O M o2 c O2

Kinetic Law

v129 = not speciﬁed (258)

208 Produced by SBML2LATEX 6.130 Reaction R CAt4 This is a reversible reaction of two reactants forming two products.

Name calcium transport in/out via proton antiporter

Reaction equation M ca2 c + M h e )−−−−* M ca2 e + M h c (259)

Reactants

Table 264: Properties of each reactant. Id Name SBO M ca2 c Calcium M h e H+

Products

Table 265: Properties of each product. Id Name SBO M ca2 e Calcium M h c H+

Kinetic Law

v130 = not speciﬁed (260)

6.131 Reaction R CBIAT This is a reversible reaction of three reactants forming two products.

Name Cobinamide adenyltransferase

Reaction equation M atp c + M cbi c + M h c )−−−−* M adocbi c + M pppi c (261)

Reactants

Produced by SBML2LATEX 209 Table 266: Properties of each reactant. Id Name SBO M atp c ATP M cbi c Cobinamide M h c H+

Products

Table 267: Properties of each product. Id Name SBO M adocbi c Adenosyl cobinamide M pppi c Inorganic triphosphate

Kinetic Law

v131 = not speciﬁed (262)

6.132 Reaction R CBLAT This is a reversible reaction of three reactants forming two products.

Name cob(I)alamin adenosyltransferase

Reaction equation M atp c + M cbl1 c + M h c )−−−−* M adocbl c + M pppi c (263)

Reactants

Table 268: Properties of each reactant. Id Name SBO M atp c ATP M cbl1 c Cob(I)alamin M h c H+

Products

210 Produced by SBML2LATEX Table 269: Properties of each product. Id Name SBO M adocbl c Adenosylcobalamin M pppi c Inorganic triphosphate

Kinetic Law

v132 = not speciﬁed (264)

6.133 Reaction R CBPS This is an irreversible reaction of four reactants forming ﬁve products.

Name carbamoyl-phosphate synthase (glutamine-hydrolysing)

Reaction equation 2M atp c + M gln DASH L c + M h2o c + M hco3 c −→ 2M adp c + M cbp c + M glu DASH L c + 2M h c + M pi c (265)

Reactants

Table 270: Properties of each reactant. Id Name SBO M atp c ATP M gln DASH L c L-Glutamine M h2o c H2O M hco3 c Bicarbonate

Products

Table 271: Properties of each product. Id Name SBO M adp c ADP M cbp c Carbamoyl phosphate M glu DASH L c L-Glutamate M h c H+ M pi c Phosphate

Produced by SBML2LATEX 211 Kinetic Law

v133 = not speciﬁed (266)

6.134 Reaction R CDAPPA160 This is an irreversible reaction of two reactants forming three products.

Name CDP-Diacylglycerol pyrophostatase (n-C16:0)

Reaction equation M cdpdhdecg c + M h2o c −→ M cmp c + 2M h c + M pa160 c (267)

Reactants

Table 272: Properties of each reactant. Id Name SBO M cdpdhdecg c CDP-1,2-dihexadecanoylglycerol M h2o c H2O

Products

Table 273: Properties of each product. Id Name SBO M cmp c CMP M h c H+ M pa160 c 1,2-dihexadecanoyl-sn-glycerol 3-phosphate

Kinetic Law

v134 = not speciﬁed (268)

6.135 Reaction R CDAPPA160190 This is an irreversible reaction of two reactants forming three products.

Name CDP-Diacylglycerol pyrophostatase (C16:0, C19:0)

Reaction equation M cdpc16c19g c + M h2o c −→ M cmp c + 2M h c + M pa160190 c (269)

212 Produced by SBML2LATEX Reactants

Table 274: Properties of each reactant. Id Name SBO M cdpc16c19g c cdp diacylglycerol (C16:0, C19:0) M h2o c H2O

Products

Table 275: Properties of each product. Id Name SBO M cmp c CMP M h c H+ M pa160190 c 1,2-sn-glycerol 3-phosphate

Kinetic Law

v135 = not speciﬁed (270)

6.136 Reaction R CDAPPA190 This is an irreversible reaction of two reactants forming three products.

Name CDP-Diacylglycerol pyrophostatase (C19:0)

Reaction equation M cdpc19c19g c + M h2o c −→ M cmp c + 2M h c + M pa190190 c (271)

Reactants

Table 276: Properties of each reactant. Id Name SBO M cdpc19c19g c cdp diacylglycerol (C19:0, C19:0) M h2o c H2O

Products

Produced by SBML2LATEX 213 Table 277: Properties of each product. Id Name SBO M cmp c CMP M h c H+ M pa190190 c 1,2-sn-glycerol 3-phosphate

Kinetic Law

v136 = not speciﬁed (272)

6.137 Reaction R CDPMEK This is an irreversible reaction of two reactants forming three products.

Name 4-(cytidine 5’-diphospho)-2-C-methyl-D-erythritol kinase

Reaction equation M 4c2me c + M atp c −→ M 2p4c2me c + M adp c + M h c (273)

Reactants

Table 278: Properties of each reactant. Id Name SBO M 4c2me c 4-(cytidine 5’-diphospho)-2-C-methyl-D-erythritol M atp c ATP

Products

Table 279: Properties of each product. Id Name SBO M 2p4c2me c 2-phospho-4-(cytidine 5’-diphospho)-2-C-methyl-D-erythritol M adp c ADP M h c H+

Kinetic Law

v137 = not speciﬁed (274)

214 Produced by SBML2LATEX 6.138 Reaction R CDPPT160 This is an irreversible reaction of two reactants forming three products.

Name CDP diacylglycerol inositon 3-phosphatidyltransferase

Reaction equation M cdpdhdecg c + M inost c −→ M cmp c + M h c + M ptd1ino160 c (275)

Reactants

Table 280: Properties of each reactant. Id Name SBO M cdpdhdecg c CDP-1,2-dihexadecanoylglycerol M inost c myo-Inositol

Products

Table 281: Properties of each product. Id Name SBO M cmp c CMP M h c H+ M ptd1ino160 c phosphatidyl 1D myo inositol

Kinetic Law

v138 = not speciﬁed (276)

6.139 Reaction R CDPPT160190 This is an irreversible reaction of two reactants forming three products.

Name CDP diacylglycerol inositon 3-phosphatidyltransferase

Reaction equation M cdpc16c19g c + M inost c −→ M cmp c + M h c + M ptd1ino160190 c (277)

Reactants

Produced by SBML2LATEX 215 Table 282: Properties of each reactant. Id Name SBO M cdpc16c19g c cdp diacylglycerol (C16:0, C19:0) M inost c myo-Inositol

Products

Table 283: Properties of each product. Id Name SBO M cmp c CMP M h c H+ M ptd1ino160190 c phosphatidyl 1D myo inositol (C16:0, C19:0)

Kinetic Law

v139 = not speciﬁed (278)

6.140 Reaction R CHLabc This is an irreversible reaction of three reactants forming four products.

Name choline transport via ABC system

Reaction equation M atp c + M chol e + M h2o c −→ M adp c + M chol c + M h c + M pi c (279)

Reactants

Table 284: Properties of each reactant. Id Name SBO M atp c ATP M chol e Choline M h2o c H2O

Products

216 Produced by SBML2LATEX Table 285: Properties of each product. Id Name SBO M adp c ADP M chol c Choline M h c H+ M pi c Phosphate

Kinetic Law

v140 = not speciﬁed (280)

6.141 Reaction R CHOLD This is an irreversible reaction of two reactants forming three products.

Name choline dehydrogenase

Reaction equation M chol c + M nad c −→ M betald c + M h c + M nadh c (281)

Reactants

Table 286: Properties of each reactant. Id Name SBO M chol c Choline M nad c Nicotinamide adenine dinucleotide

Products

Table 287: Properties of each product. Id Name SBO M betald c Betaine aldehyde M h c H+ M nadh c Nicotinamide adenine dinucleotide - reduced

Kinetic Law

v141 = not speciﬁed (282)

Produced by SBML2LATEX 217 6.142 Reaction R CHORM This is an irreversible reaction of one reactant forming one product.

Name chorismate mutase

Reaction equation M chor c −→ M pphn c (283)

Reactant

Table 288: Properties of each reactant. Id Name SBO M chor c chorismate

Product

Table 289: Properties of each product. Id Name SBO M pphn c Prephenate

Kinetic Law

v142 = not speciﬁed (284)

6.143 Reaction R CHORS This is an irreversible reaction of one reactant forming two products.

Name chorismate synthase

Reaction equation M 3psme c −→ M chor c + M pi c (285)

Reactant

218 Produced by SBML2LATEX Table 290: Properties of each reactant. Id Name SBO M 3psme c 5-O-(1-Carboxyvinyl)-3-phosphoshikimate

Products

Table 291: Properties of each product. Id Name SBO M chor c chorismate M pi c Phosphate

Kinetic Law

v143 = not speciﬁed (286)

6.144 Reaction R CHRPL This is an irreversible reaction of one reactant forming two products.

Name Chorismate pyruvate lyase

Reaction equation M chor c −→ M 4hbz c + M pyr c (287)

Reactant

Table 292: Properties of each reactant. Id Name SBO M chor c chorismate

Products

Table 293: Properties of each product. Id Name SBO M 4hbz c 4-Hydroxybenzoate M pyr c Pyruvate

Produced by SBML2LATEX 219 Kinetic Law

v144 = not speciﬁed (288)

6.145 Reaction R CIGAMS This is an irreversible reaction of three reactants forming four products.

Name cys-1D-myo-inositol 2-deoxy-D-glucopyranoside synthase

Reaction equation M atp c + M cys DASH L c + M igam c −→ M amp c + M cigam c + 2M h c + M ppi c (289)

Reactants

Table 294: Properties of each reactant. Id Name SBO M atp c ATP M cys DASH L c L-Cysteine M igam c 1D-myo-inositol 2-deoxy-D-glucopyranoside

Products

Table 295: Properties of each product. Id Name SBO M amp c AMP M cigam c cys-1D-myo-inositol 2-deoxy-D-glucopyranoside M h c H+ M ppi c Diphosphate

Kinetic Law

v145 = not speciﬁed (290)

6.146 Reaction R CITL This is an irreversible reaction of one reactant forming two products.

Name Citrate lyase

220 Produced by SBML2LATEX Reaction equation M cit c −→ M ac c + M oaa c (291)

Reactant

Table 296: Properties of each reactant. Id Name SBO M cit c Citrate

Products

Table 297: Properties of each product. Id Name SBO M ac c Acetate M oaa c Oxaloacetate

Kinetic Law

v146 = not speciﬁed (292)

6.147 Reaction R CITLr This is a reversible reaction of one reactant forming two products.

Name Citrate lyase (reversible)

Reaction equation M cit c )−−−−* M ac c + M oaa c (293)

Reactant

Table 298: Properties of each reactant. Id Name SBO M cit c Citrate

Products

Produced by SBML2LATEX 221 Table 299: Properties of each product. Id Name SBO M ac c Acetate M oaa c Oxaloacetate

Kinetic Law

v147 = not speciﬁed (294)

6.148 Reaction R CITabc This is an irreversible reaction of three reactants forming four products.

Name citrate transport via ABC system

Reaction equation M atp c + M cit e + M h2o c −→ M adp c + M cit c + M h c + M pi c (295)

Reactants

Table 300: Properties of each reactant. Id Name SBO M atp c ATP M cit e Citrate M h2o c H2O

Products

Table 301: Properties of each product. Id Name SBO M adp c ADP M cit c Citrate M h c H+ M pi c Phosphate

Kinetic Law

v148 = not speciﬁed (296)

222 Produced by SBML2LATEX 6.149 Reaction R CLPNS160190 This is a reversible reaction of one reactant forming two products.

Name cardiolipin synthase (C16:0, C19:0) tuberculosis

Reaction equation 2M pg160190 c )−−−−* M clpn160190 c + M glyc c (297)

Reactant

Table 302: Properties of each reactant. Id Name SBO M pg160190 c Phosphatidylglycerol (hexadecanoyl, methylstearoyl)

Products

Table 303: Properties of each product. Id Name SBO M clpn160190 c cardiolipin (dihexadecanoyl, dimethylstearoyl) M glyc c Glycerol

Kinetic Law

v149 = not speciﬁed (298)

6.150 Reaction R CMCBTFL This is an irreversible reaction of two reactants forming one product.

Name carboxymycobactin Fe3 loading

Reaction equation M cmcbtt c + M fe3 e −→ M fcmcbtt c (299)

Reactants

Produced by SBML2LATEX 223 Table 304: Properties of each reactant. Id Name SBO M cmcbtt c carboxymycobactin T (R=8 carbon, ﬁnal carbon is carboxyl group) M fe3 e Fe3+

Product

Table 305: Properties of each product. Id Name SBO M fcmcbtt c iron(III) chelated carboxymycobactin T (R=8 carbon, ﬁnal carbon is carboxyl group)

Kinetic Law

v150 = not speciﬁed (300)

6.151 Reaction R CMCBTFU This is an irreversible reaction of one reactant forming two products.

Name carboxymycobactin Fe3 unloading

Reaction equation M fcmcbtt c −→ M cmcbtt c + M fe3 c (301)

Reactant

Table 306: Properties of each reactant. Id Name SBO M fcmcbtt c iron(III) chelated carboxymycobactin T (R=8 carbon, ﬁnal carbon is carboxyl group)

Products

Table 307: Properties of each product. Id Name SBO M cmcbtt c carboxymycobactin T (R=8 carbon, ﬁnal carbon is carboxyl group) M fe3 c Fe3+

224 Produced by SBML2LATEX Kinetic Law

v151 = not speciﬁed (302)

6.152 Reaction R CMLDC This is an irreversible reaction of one reactant forming three products.

Name 4-carboxymuconolactone decarboxylase

Reaction equation M 2c25dho c −→ M 5odhf2a c + M co2 c + M h c (303)

Reactant

Table 308: Properties of each reactant. Id Name SBO M 2c25dho c 2-Carboxy-2,5-dihydro-5-oxofuran-2-acetate

Products

Table 309: Properties of each product. Id Name SBO M 5odhf2a c 5-Oxo-4,5-dihydrofuran-2-acetate M co2 c CO2 M h c H+

Kinetic Law

v152 = not speciﬁed (304)

6.153 Reaction R CO2t This is a reversible reaction of one reactant forming one product.

Name CO2 transporter via diffusion

Reaction equation

M co2 e )−−−−* M co2 c (305)

Produced by SBML2LATEX 225 Reactant

Table 310: Properties of each reactant. Id Name SBO M co2 e CO2

Product

Table 311: Properties of each product. Id Name SBO M co2 c CO2

Kinetic Law

v153 = not speciﬁed (306)

6.154 Reaction R COAt This is a reversible reaction of one reactant forming one product.

Name CoA transporter

Reaction equation M coa e )−−−−* M coa c (307)

Reactant

Table 312: Properties of each reactant. Id Name SBO M coa e Coenzyme A

Product

Table 313: Properties of each product. Id Name SBO M coa c Coenzyme A

226 Produced by SBML2LATEX Kinetic Law

v154 = not speciﬁed (308)

6.155 Reaction R COBALTt5 This is a reversible reaction of one reactant forming one product.

Name cobalt transport in/out via permease (no H+)

Reaction equation M cobalt2 c )−−−−* M cobalt2 e (309)

Reactant

Table 314: Properties of each reactant. Id Name SBO M cobalt2 c Co2+

Product

Table 315: Properties of each product. Id Name SBO M cobalt2 e Co2+

Kinetic Law

v155 = not speciﬁed (310)

6.156 Reaction R COCHL This is an irreversible reaction of four reactants forming four products.

Name cobaltochelatase

Reaction equation

M atp c + M cobalt2 c + M h2o c + M hgbam c −→ M adp c + M co2dam c + 2M h c + M pi c (311)

Produced by SBML2LATEX 227 Reactants

228 Produced by SBML2LATEX Table 316: Properties of each reactant. Id Name SBO M atp c ATP M cobalt2 c Co2+ M h2o c H2O M hgbam c Hydrogenobyrinate a,c diamide

Products

Table 317: Properties of each product. Id Name SBO M adp c ADP M co2dam c Cob(II)yrinate a,c diamide M h c H+ M pi c Phosphate

Kinetic Law

v156 = not speciﬁed (312)

6.157 Reaction R CODH2r This is a reversible reaction of three reactants forming three products.

Name carbon monoxide dehydrogenase / acetyl-CoA synthase 2

Reaction equation M co c + 2M fdox c + M h2o c )−−−−* M co2 c + 2M fdred c + 2M h c (313)

Reactants

Table 318: Properties of each reactant. Id Name SBO M co c Carbon monoxide M fdox c ferredoxin (oxidized) 2[4Fe-4S] M h2o c H2O

Produced by SBML2LATEX 229 Products

Table 319: Properties of each product. Id Name SBO M co2 c CO2 M fdred c ferredoxin (reduced) 2[4Fe-4S] M h c H+

Kinetic Law

v157 = not speciﬁed (314)

6.158 Reaction R CODH3 This is an irreversible reaction of three reactants forming three products.

Name carbon monoxide dehydrogenase / acetyl-CoA synthase 2

Reaction equation M adfdOX c + 2M co c + 2M h2o c −→ M adfdRD c + 2M co2 c + 2M h c (315)

Reactants

Table 320: Properties of each reactant. Id Name SBO M adfdOX c Oxidized adrenal ferredoxin M co c Carbon monoxide M h2o c H2O

Products

Table 321: Properties of each product. Id Name SBO M adfdRD c Reduced adrenal ferredoxin M co2 c CO2 M h c H+

230 Produced by SBML2LATEX Kinetic Law

v158 = not speciﬁed (316)

6.159 Reaction R COt This is a reversible reaction of one reactant forming one product.

Name CO transporter via diffusion

Reaction equation M co c )−−−−* M co e (317)

Reactant

Table 322: Properties of each reactant. Id Name SBO M co c Carbon monoxide

Product

Table 323: Properties of each product. Id Name SBO M co e Carbon monoxide

Kinetic Law

v159 = not speciﬁed (318)

6.160 Reaction R CPC2MT This is an irreversible reaction of two reactants forming three products. Name precorrin-2 C20-methyltransferase

Reaction equation M amet c + M copre2 c −→ M ahcys c + M copre3 c + M h c (319)

Reactants

Produced by SBML2LATEX 231 Table 324: Properties of each reactant. Id Name SBO M amet c S-Adenosyl-L-methionine M copre2 c cobalt-precorrin 2

Products

Table 325: Properties of each product. Id Name SBO M ahcys c S-Adenosyl-L-homocysteine M copre3 c cobalt-precorrin 3 M h c H+

Kinetic Law

v160 = not speciﬁed (320)

6.161 Reaction R CPC3MT This is an irreversible reaction of two reactants forming two products.

Name precorrin-3B C17-methyltransferase

Reaction equation M amet c + M copre3 c −→ M ahcys c + M copre4 c (321)

Reactants

Table 326: Properties of each reactant. Id Name SBO M amet c S-Adenosyl-L-methionine M copre3 c cobalt-precorrin 3

Products

232 Produced by SBML2LATEX Table 327: Properties of each product. Id Name SBO M ahcys c S-Adenosyl-L-homocysteine M copre4 c cobalt-precorrin 4

Kinetic Law

v161 = not speciﬁed (322)

6.162 Reaction R CPC4MT This is an irreversible reaction of two reactants forming three products.

Name precorrin-4 C11-methyltransferase

Reaction equation M amet c + M copre4 c −→ M ahcys c + M copre5 c + M h c (323)

Reactants

Table 328: Properties of each reactant. Id Name SBO M amet c S-Adenosyl-L-methionine M copre4 c cobalt-precorrin 4

Products

Table 329: Properties of each product. Id Name SBO M ahcys c S-Adenosyl-L-homocysteine M copre5 c cobalt-precorrin 5 M h c H+

Kinetic Law

v162 = not speciﬁed (324)

Produced by SBML2LATEX 233 6.163 Reaction R CPC6MT This is an irreversible reaction of two reactants forming four products.

Name precorrin-6Y C5,15-methyltransferase (decarboxylating)

Reaction equation 2M amet c + M codhpre6 c −→ 2M ahcys c + M co2 c + M copre8 c + M h c (325)

Reactants

Table 330: Properties of each reactant. Id Name SBO M amet c S-Adenosyl-L-methionine M codhpre6 c cobalt-dihydro-precorrin 6

Products

Table 331: Properties of each product. Id Name SBO M ahcys c S-Adenosyl-L-homocysteine M co2 c CO2 M copre8 c cobalt-precorrin 8 M h c H+

Kinetic Law

v163 = not speciﬁed (326)

6.164 Reaction R CPC6R This is an irreversible reaction of three reactants forming two products.

Name precorrin-6A reductase

Reaction equation M copre6 c + M h c + M nadph c −→ M codhpre6 c + M nadp c (327)

Reactants

234 Produced by SBML2LATEX Table 332: Properties of each reactant. Id Name SBO M copre6 c cobalt-precorrin 6 M h c H+ M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

Products

Table 333: Properties of each product. Id Name SBO M codhpre6 c cobalt-dihydro-precorrin 6 M nadp c Nicotinamide adenine dinucleotide phosphate

Kinetic Law

v164 = not speciﬁed (328)

6.165 Reaction R CPC8MM This is a reversible reaction of one reactant forming one product.

Name precorrin-8X methylmutase

Reaction equation M copre8 c )−−−−* M cobya c (329)

Reactant

Table 334: Properties of each reactant. Id Name SBO M copre8 c cobalt-precorrin 8

Product

Table 335: Properties of each product. Id Name SBO M cobya c Cobyrinate

Produced by SBML2LATEX 235 Id Name SBO

Kinetic Law

v165 = not speciﬁed (330)

6.166 Reaction R CPPPGO This is an irreversible reaction of three reactants forming three products.

Name coproporphyrinogen oxidase (O2 required)

Reaction equation M cpppg3 c + 2M h c + M o2 c −→ 2M co2 c + 2M h2o c + M pppg9 c (331)

Reactants

Table 336: Properties of each reactant. Id Name SBO M cpppg3 c Coproporphyrinogen III M h c H+ M o2 c O2

Products

Table 337: Properties of each product. Id Name SBO M co2 c CO2 M h2o c H2O M pppg9 c Protoporphyrinogen IX

Kinetic Law

v166 = not speciﬁed (332)

6.167 Reaction R CRNabc This is an irreversible reaction of three reactants forming four products. Name L-carnitine transport via ABC system

236 Produced by SBML2LATEX Reaction equation M atp c + M crn e + M h2o c −→ M adp c + M crn c + M h c + M pi c (333)

Reactants

Table 338: Properties of each reactant. Id Name SBO M atp c ATP M crn e L-Carnitine M h2o c H2O

Products

Table 339: Properties of each product. Id Name SBO M adp c ADP M crn c L-Carnitine M h c H+ M pi c Phosphate

Kinetic Law

v167 = not speciﬁed (334)

6.168 Reaction R CS This is an irreversible reaction of three reactants forming three products.

Name citrate synthase

Reaction equation M accoa c + M h2o c + M oaa c −→ M cit c + M coa c + M h c (335)

Reactants

Table 340: Properties of each reactant. Id Name SBO M accoa c Acetyl-CoA

Produced by SBML2LATEX 237 Id Name SBO M h2o c H2O M oaa c Oxaloacetate

Products

Table 341: Properties of each product. Id Name SBO M cit c Citrate M coa c Coenzyme A M h c H+

Kinetic Law

v168 = not speciﬁed (336)

6.169 Reaction R CTPS1 This is an irreversible reaction of three reactants forming four products.

Name CTP synthase (NH3)

Reaction equation M atp c + M nh4 c + M utp c −→ M adp c + M ctp c + 2M h c + M pi c (337)

Reactants

Table 342: Properties of each reactant. Id Name SBO M atp c ATP M nh4 c Ammonium M utp c UTP

Products

238 Produced by SBML2LATEX Table 343: Properties of each product. Id Name SBO M adp c ADP M ctp c CTP M h c H+ M pi c Phosphate

Kinetic Law

v169 = not speciﬁed (338)

6.170 Reaction R CTPS2 This is an irreversible reaction of four reactants forming ﬁve products.

Name CTP synthase (glutamine)

Reaction equation M atp c + M gln DASH L c + M h2o c + M utp c −→ M adp c + M ctp c + M glu DASH L c + 2M h c + M pi c (339)

Reactants

Table 344: Properties of each reactant. Id Name SBO M atp c ATP M gln DASH L c L-Glutamine M h2o c H2O M utp c UTP

Products

Table 345: Properties of each product. Id Name SBO M adp c ADP M ctp c CTP M glu DASH L c L-Glutamate M h c H+

Produced by SBML2LATEX 239 Id Name SBO M pi c Phosphate

Kinetic Law

v170 = not speciﬁed (340)

6.171 Reaction R CYANST This is an irreversible reaction of two reactants forming three products.

Name Cyanide sulfurtransferase

Reaction equation M cyan c + M tsul c −→ M h c + M so3 c + M tcynt c (341)

Reactants

Table 346: Properties of each reactant. Id Name SBO M cyan c Hydrogen cyanide M tsul c Thiosulfate

Products

Table 347: Properties of each product. Id Name SBO M h c H+ M so3 c Sulﬁte M tcynt c Thiocyanate

Kinetic Law

v171 = not speciﬁed (342)

6.172 Reaction R CYO1a This is an irreversible reaction of three reactants forming three products. Name cytochrome-c reductase (ubiquinol: 2 protons)

240 Produced by SBML2LATEX Reaction equation 2M ﬁcytc c + 2M h c + M qh2 c −→ 2M focytc c + 2M h e + M q c (343)

Reactants

Table 348: Properties of each reactant. Id Name SBO M ficytc c Ferricytochrome c M h c H+ M qh2 c Ubiquinol

Products

Table 349: Properties of each product. Id Name SBO M focytc c Ferrocytochrome c M h e H+ M q c Ubiquinone

Kinetic Law

v172 = not speciﬁed (344)

6.173 Reaction R CYO1b This is an irreversible reaction of two reactants forming two products.

Name cytochrome-c oxidase (2 protons)

Reaction equation 2M focytc c + 0·5M o2 c −→ 2M ﬁcytc c + M h2o c (345)

Reactants

Table 350: Properties of each reactant. Id Name SBO M focytc c Ferrocytochrome c M o2 c O2

Produced by SBML2LATEX 241 Products

Table 351: Properties of each product. Id Name SBO M ficytc c Ferricytochrome c M h2o c H2O

Kinetic Law

v173 = not speciﬁed (346)

6.174 Reaction R CYRDAAT This is an irreversible reaction of three reactants forming two products.

Name cob(I)yrinic acid a,c-diamide adenosyltransferase

Reaction equation M atp c + M co1dam c + M h c −→ M adcobdam c + M pppi c (347)

Reactants

Table 352: Properties of each reactant. Id Name SBO M atp c ATP M co1dam c Cob(I)yrinate a,c diamide M h c H+

Products

Table 353: Properties of each product. Id Name SBO M adcobdam c Adenosyl cobyrinate diamide M pppi c Inorganic triphosphate

Kinetic Law

v174 = not speciﬁed (348)

242 Produced by SBML2LATEX 6.175 Reaction R CYRDAR This is an irreversible reaction of two reactants forming three products.

Name cob(II)yrinic acid a,c-diamide reductase

Reaction equation 2M co2dam c + M nadh c −→ 2M co1dam c + M h c + M nad c (349)

Reactants

Table 354: Properties of each reactant. Id Name SBO M co2dam c Cob(II)yrinate a,c diamide M nadh c Nicotinamide adenine dinucleotide - reduced

Products

Table 355: Properties of each product. Id Name SBO M co1dam c Cob(I)yrinate a,c diamide M h c H+ M nad c Nicotinamide adenine dinucleotide

Kinetic Law

v175 = not speciﬁed (350)

6.176 Reaction R CYSS This is an irreversible reaction of two reactants forming three products.

Name cysteine synthase

Reaction equation M acser c + M h2s c −→ M ac c + M cys DASH L c + M h c (351)

Reactants

Produced by SBML2LATEX 243 Table 356: Properties of each reactant. Id Name SBO M acser c O-Acetyl-L-serine M h2s c Hydrogen sulﬁde

Products

Table 357: Properties of each product. Id Name SBO M ac c Acetate M cys DASH L c L-Cysteine M h c H+

Kinetic Law

v176 = not speciﬁed (352)

6.177 Reaction R CYSTGL This is an irreversible reaction of two reactants forming three products.

Name cystathionine g-lyase

Reaction equation M cyst DASH L c + M h2o c −→ M 2obut c + M cys DASH L c + M nh4 c (353)

Reactants

Table 358: Properties of each reactant. Id Name SBO M cyst DASH L c L-Cystathionine M h2o c H2O

Products

244 Produced by SBML2LATEX Table 359: Properties of each product. Id Name SBO M 2obut c 2-Oxobutanoate M cys DASH L c L-Cysteine M nh4 c Ammonium

Kinetic Law

v177 = not speciﬁed (354)

6.178 Reaction R CYSTL This is an irreversible reaction of two reactants forming three products.

Name cystathionine b-lyase

Reaction equation M cyst DASH L c + M h2o c −→ M hcys DASH L c + M nh4 c + M pyr c (355)

Reactants

Table 360: Properties of each reactant. Id Name SBO M cyst DASH L c L-Cystathionine M h2o c H2O

Products

Table 361: Properties of each product. Id Name SBO M hcys DASH L c L-Homocysteine M nh4 c Ammonium M pyr c Pyruvate

Kinetic Law

v178 = not speciﬁed (356)

Produced by SBML2LATEX 245 6.179 Reaction R CYSTS This is an irreversible reaction of two reactants forming two products.

Name cystathionine beta-synthase

Reaction equation M hcys DASH L c + M ser DASH L c −→ M cyst DASH L c + M h2o c (357)

Reactants

Table 362: Properties of each reactant. Id Name SBO M hcys DASH L c L-Homocysteine M ser DASH L c L-Serine

Products

Table 363: Properties of each product. Id Name SBO M cyst DASH L c L-Cystathionine M h2o c H2O

Kinetic Law

v179 = not speciﬁed (358)

6.180 Reaction R CYTBD This is an irreversible reaction of three reactants forming three products.

Name cytochrome oxidase bd (ubiquinol-8: 2 protons)

Reaction equation 2M h c + 0·5M o2 c + M q8h2 c −→ M h2o c + 2M h e + M q8 c (359)

Reactants

246 Produced by SBML2LATEX Table 364: Properties of each reactant. Id Name SBO M h c H+ M o2 c O2 M q8h2 c Ubiquinol-8

Products

Table 365: Properties of each product. Id Name SBO M h2o c H2O M h e H+ M q8 c Ubiquinone-8

Kinetic Law

v180 = not speciﬁed (360)

6.181 Reaction R CYTBD2 This is an irreversible reaction of three reactants forming three products.

Name cytochrome oxidase bd (menaquinol-8: 2 protons)

Reaction equation 2M h c + M mql8 c + 0·5M o2 c −→ M h2o c + 2M h e + M mqn8 c (361)

Reactants

Table 366: Properties of each reactant. Id Name SBO M h c H+ M mql8 c Menaquinol 8 M o2 c O2

Products

Produced by SBML2LATEX 247 Table 367: Properties of each product. Id Name SBO M h2o c H2O M h e H+ M mqn8 c Menaquinone 8

Kinetic Law

v181 = not speciﬁed (362)

6.182 Reaction R CYTD This is an irreversible reaction of three reactants forming two products.

Name cytidine deaminase

Reaction equation M cytd c + M h2o c + M h c −→ M nh4 c + M uri c (363)

Reactants

Table 368: Properties of each reactant. Id Name SBO M cytd c Cytidine M h2o c H2O M h c H+

Products

Table 369: Properties of each product. Id Name SBO M nh4 c Ammonium M uri c Uridine

Kinetic Law

v182 = not speciﬁed (364)

248 Produced by SBML2LATEX 6.183 Reaction R CYTDK2 This is an irreversible reaction of two reactants forming three products.

Name cytidine kinase (GTP)

Reaction equation M cytd c + M gtp c −→ M cmp c + M gdp c + M h c (365)

Reactants

Table 370: Properties of each reactant. Id Name SBO M cytd c Cytidine M gtp c GTP

Products

Table 371: Properties of each product. Id Name SBO M cmp c CMP M gdp c GDP M h c H+

Kinetic Law

v183 = not speciﬁed (366)

6.184 Reaction R CYTDt2r This is a reversible reaction of two reactants forming two products.

Name cytidine transport in via proton symport, reversible

Reaction equation M cytd e + M h e )−−−−* M cytd c + M h c (367)

Reactants

Produced by SBML2LATEX 249 Table 372: Properties of each reactant. Id Name SBO M cytd e Cytidine M h e H+

Products

Table 373: Properties of each product. Id Name SBO M cytd c Cytidine M h c H+

Kinetic Law

v184 = not speciﬁed (368)

6.185 Reaction R CYTK1 This is a reversible reaction of two reactants forming two products.

Name cytidylate kinase (CMP)

Reaction equation M atp c + M cmp c )−−−−* M adp c + M cdp c (369)

Reactants

Table 374: Properties of each reactant. Id Name SBO M atp c ATP M cmp c CMP

Products

Table 375: Properties of each product. Id Name SBO M adp c ADP

250 Produced by SBML2LATEX Id Name SBO M cdp c CDP

Kinetic Law

v185 = not speciﬁed (370)

6.186 Reaction R CYTK2 This is a reversible reaction of two reactants forming two products.

Name cytidylate kinase (dCMP)

Reaction equation M atp c + M dcmp c )−−−−* M adp c + M dcdp c (371)

Reactants

Table 376: Properties of each reactant. Id Name SBO M atp c ATP M dcmp c dCMP

Products

Table 377: Properties of each product. Id Name SBO M adp c ADP M dcdp c dCDP

Kinetic Law

v186 = not speciﬁed (372)

6.187 Reaction R Clt This is a reversible reaction of one reactant forming one product.

Name chlorideion transport out via diffusion

Produced by SBML2LATEX 251 Reaction equation M cl e )−−−−* M cl c (373)

Reactant

Table 378: Properties of each reactant. Id Name SBO M cl e Chloride

Product

Table 379: Properties of each product. Id Name SBO M cl c Chloride

Kinetic Law

v187 = not speciﬁed (374)

6.188 Reaction R Cuabc This is an irreversible reaction of three reactants forming four products.

Name Copper transport via ABC system

Reaction equation M atp c + M cu2 e + M h2o c −→ M adp c + M cu2 c + M h c + M pi c (375)

Reactants

Table 380: Properties of each reactant. Id Name SBO M atp c ATP M cu2 e Cu2+ M h2o c H2O

252 Produced by SBML2LATEX Products

Table 381: Properties of each product. Id Name SBO M adp c ADP M cu2 c Cu2+ M h c H+ M pi c Phosphate

Kinetic Law

v188 = not speciﬁed (376)

6.189 Reaction R Cut1 This is an irreversible reaction of three reactants forming four products.

Name Copper export via ATPase

Reaction equation M atp c + M cu2 c + M h2o c −→ M adp c + M cu2 e + M h c + M pi c (377)

Reactants

Table 382: Properties of each reactant. Id Name SBO M atp c ATP M cu2 c Cu2+ M h2o c H2O

Products

Table 383: Properties of each product. Id Name SBO M adp c ADP M cu2 e Cu2+ M h c H+ M pi c Phosphate

Produced by SBML2LATEX 253 Kinetic Law

v189 = not speciﬁed (378)

6.190 Reaction R DADA This is an irreversible reaction of three reactants forming two products.

Name Deoxyadenosine deaminase

Reaction equation M dad DASH 2 c + M h2o c + M h c −→ M din c + M nh4 c (379)

Reactants

Table 384: Properties of each reactant. Id Name SBO M dad DASH 2 c Deoxyadenosine M h2o c H2O M h c H+

Products

Table 385: Properties of each product. Id Name SBO M din c Deoxyinosine M nh4 c Ammonium

Kinetic Law

v190 = not speciﬁed (380)

6.191 Reaction R DADK This is a reversible reaction of two reactants forming two products.

Name deoxyadenylate kinase

Reaction equation M atp c + M damp c )−−−−* M adp c + M dadp c (381)

254 Produced by SBML2LATEX Reactants

Table 386: Properties of each reactant. Id Name SBO M atp c ATP M damp c dAMP

Products

Table 387: Properties of each product. Id Name SBO M adp c ADP M dadp c dADP

Kinetic Law

v191 = not speciﬁed (382)

6.192 Reaction R DAGK160 This is an irreversible reaction of two reactants forming three products.

Name diacylglycerol kinase (n-C16:0)

Reaction equation M 12dgr160 c + M atp c −→ M adp c + M h c + M pa160 c (383)

Reactants

Table 388: Properties of each reactant. Id Name SBO M 12dgr160 c 1,2-Diacyl-sn-glycerol (dihexadecanoyl, n-C16:0) M atp c ATP

Products

Produced by SBML2LATEX 255 Table 389: Properties of each product. Id Name SBO M adp c ADP M h c H+ M pa160 c 1,2-dihexadecanoyl-sn-glycerol 3-phosphate

Kinetic Law

v192 = not speciﬁed (384)

6.193 Reaction R DALAOX This is an irreversible reaction of three reactants forming three products.

Name D-Alanine Oxidase

Reaction equation M ala DASH D c + M h2o c + M o2 c −→ M h2o2 c + M nh4 c + M pyr c (385)

Reactants

Table 390: Properties of each reactant. Id Name SBO M ala DASH D c D-Alanine M h2o c H2O M o2 c O2

Products

Table 391: Properties of each product. Id Name SBO M h2o2 c Hydrogen peroxide M nh4 c Ammonium M pyr c Pyruvate

Kinetic Law

v193 = not speciﬁed (386)

256 Produced by SBML2LATEX 6.194 Reaction R DALAt2r This is a reversible reaction of two reactants forming two products.

Name D-alanine transport via proton symport

Reaction equation M ala DASH D e + M h e )−−−−* M ala DASH D c + M h c (387)

Reactants

Table 392: Properties of each reactant. Id Name SBO M ala DASH D e D-Alanine M h e H+

Products

Table 393: Properties of each product. Id Name SBO M ala DASH D c D-Alanine M h c H+

Kinetic Law

v194 = not speciﬁed (388)

6.195 Reaction R DAPDC This is an irreversible reaction of two reactants forming two products.

Name diaminopimelate decarboxylase

Reaction equation M 26dap DASH M c + M h c −→ M co2 c + M lys DASH L c (389)

Reactants

Produced by SBML2LATEX 257 Table 394: Properties of each reactant. Id Name SBO M 26dap DASH M c meso-2,6-Diaminoheptanedioate M h c H+

Products

Table 395: Properties of each product. Id Name SBO M co2 c CO2 M lys DASH L c L-Lysine

Kinetic Law

v195 = not speciﬁed (390)

6.196 Reaction R DAPE This is a reversible reaction of one reactant forming one product.

Name diaminopimelate epimerase

Reaction equation M 26dap DASH LL c )−−−−* M 26dap DASH M c (391)

Reactant

Table 396: Properties of each reactant. Id Name SBO M 26dap DASH LL c LL-2,6-Diaminoheptanedioate

Product

Table 397: Properties of each product. Id Name SBO M 26dap DASH M c meso-2,6-Diaminoheptanedioate

258 Produced by SBML2LATEX Kinetic Law

v196 = not speciﬁed (392)

6.197 Reaction R DASYN160 This is an irreversible reaction of three reactants forming two products.

Name CDP-diacylglycerol synthetase (n-C16:0)

Reaction equation M ctp c + M h c + M pa160 c −→ M cdpdhdecg c + M ppi c (393)

Reactants

Table 398: Properties of each reactant. Id Name SBO M ctp c CTP M h c H+ M pa160 c 1,2-dihexadecanoyl-sn-glycerol 3-phosphate

Products

Table 399: Properties of each product. Id Name SBO M cdpdhdecg c CDP-1,2-dihexadecanoylglycerol M ppi c Diphosphate

Kinetic Law

v197 = not speciﬁed (394)

6.198 Reaction R DASYN160190 This is an irreversible reaction of three reactants forming two products.

Name CDP-diacylglycerol synthetase (C16:0, C19:0)

Reaction equation M ctp c + M h c + M pa160190 c −→ M cdpc16c19g c + M ppi c (395)

Produced by SBML2LATEX 259 Reactants

Table 400: Properties of each reactant. Id Name SBO M ctp c CTP M h c H+ M pa160190 c 1,2-sn-glycerol 3-phosphate

Products

Table 401: Properties of each product. Id Name SBO M cdpc16c19g c cdp diacylglycerol (C16:0, C19:0) M ppi c Diphosphate

Kinetic Law

v198 = not speciﬁed (396)

6.199 Reaction R DASYN190190 This is an irreversible reaction of three reactants forming two products.

Name CDP-diacylglycerol synthetase (C19:0, C19:0)

Reaction equation M ctp c + M h c + M pa190190 c −→ M cdpc19c19g c + M ppi c (397)

Reactants

Table 402: Properties of each reactant. Id Name SBO M ctp c CTP M h c H+ M pa190190 c 1,2-sn-glycerol 3-phosphate

Products

260 Produced by SBML2LATEX Table 403: Properties of each product. Id Name SBO M cdpc19c19g c cdp diacylglycerol (C19:0, C19:0) M ppi c Diphosphate

Kinetic Law

v199 = not speciﬁed (398)

6.200 Reaction R DB4PS This is an irreversible reaction of one reactant forming three products.

Name 3,4-Dihydroxy-2-butanone-4-phosphate synthase

Reaction equation M ru5p DASH D c −→ M db4p c + M for c + M h c (399)

Reactant

Table 404: Properties of each reactant. Id Name SBO M ru5p DASH D c D-Ribulose 5-phosphate

Products

Table 405: Properties of each product. Id Name SBO M db4p c 3,4-dihydroxy-2-butanone 4-phosphate M for c Formate M h c H+

Kinetic Law

v200 = not speciﬁed (400)

6.201 Reaction R DBTSr This is a reversible reaction of three reactants forming four products.

Produced by SBML2LATEX 261 Name dethiobiotin synthase

Reaction equation M atp c + M co2 c + M dann c )−−−−* M adp c + M dtbt c + 3M h c + M pi c (401)

Reactants

Table 406: Properties of each reactant. Id Name SBO M atp c ATP M co2 c CO2 M dann c 7,8-Diaminononanoate

Products

Table 407: Properties of each product. Id Name SBO M adp c ADP M dtbt c Dethiobiotin M h c H+ M pi c Phosphate

Kinetic Law

v201 = not speciﬁed (402)

6.202 Reaction R DCPDP This is an irreversible reaction of two reactants forming three products.

Name decaprenyl-diphosphatase

Reaction equation M decdp tb c + M h2o c −→ M decd tb c + M h c + M pi c (403)

Reactants

262 Produced by SBML2LATEX Table 408: Properties of each reactant. Id Name SBO M decdp tb c (E,E,E,E,E,E,E,Z,Z) Decaprenyl diphosphate M h2o c H2O

Products

Table 409: Properties of each product. Id Name SBO M decd tb c (E,E,E,E,E,E,E,Z,Z) decaprenyl phosphate M h c H+ M pi c Phosphate

Kinetic Law

v202 = not speciﬁed (404)

6.203 Reaction R DCPDPP This is an irreversible reaction of two reactants forming two products.

Name decaprenylphosphoryl ribose phosphate dephosphatase

Reaction equation M decdpr tb c + M h2o c −→ M decdr tb c + M pi c (405)

Reactants

Table 410: Properties of each reactant. Id Name SBO M decdpr tb c decaprenylphosphoryl-beta-D-5-phosphoribose M h2o c H2O

Products

Produced by SBML2LATEX 263 Table 411: Properties of each product. Id Name SBO M decdr tb c decaprenylphosphoryl-beta-D-5-ribose M pi c Phosphate

Kinetic Law

v203 = not speciﬁed (406)

6.204 Reaction R DCPDPP2 This is an irreversible reaction of two reactants forming two products.

Name decaprenylphosphoryl arabinose phosphate dephosphatase

Reaction equation M decdpa tb c + M h2o c −→ M decda tb c + M pi c (407)

Reactants

Table 412: Properties of each reactant. Id Name SBO M decdpa tb c decaprenylphosphoryl-beta-D-5-phosphoarabinofuranose M h2o c H2O

Products

Table 413: Properties of each product. Id Name SBO M decda tb c decaprenylphosphoryl-beta-D-arabinofuranose M pi c Phosphate

Kinetic Law

v204 = not speciﬁed (408)

6.205 Reaction R DCPDPS This is an irreversible reaction of two reactants forming two products.

264 Produced by SBML2LATEX Name Decaprenyl diphosphate synthase

Reaction equation M frdp c + 7M ipdp c −→ M decdp tb c + 7M ppi c (409)

Reactants

Table 414: Properties of each reactant. Id Name SBO M frdp c Farnesyl diphosphate M ipdp c Isopentenyl diphosphate

Products

Table 415: Properties of each product. Id Name SBO M decdp tb c (E,E,E,E,E,E,E,Z,Z) Decaprenyl diphosphate M ppi c Diphosphate

Kinetic Law

v205 = not speciﬁed (410)

6.206 Reaction R DCPE This is a reversible reaction of one reactant forming one product.

Name decaprenylphosphoryl ribose, arabinofuranose isomerization

Reaction equation M decdr tb c )−−−−* M decda tb c (411)

Reactant

Table 416: Properties of each reactant. Id Name SBO M decdr tb c decaprenylphosphoryl-beta-D-5-ribose

Produced by SBML2LATEX 265 Product

Table 417: Properties of each product. Id Name SBO M decda tb c decaprenylphosphoryl-beta-D-arabinofuranose

Kinetic Law

v206 = not speciﬁed (412)

6.207 Reaction R DCPT This is an irreversible reaction of two reactants forming two products.

Name phosphoribose transferase (undecaprenyl phosphate)

Reaction equation M decd tb c + M prpp c −→ M decdpr tb c + M ppi c (413)

Reactants

Table 418: Properties of each reactant. Id Name SBO M decd tb c (E,E,E,E,E,E,E,Z,Z) decaprenyl phosphate M prpp c 5-Phospho-alpha-D-ribose 1-diphosphate

Products

Table 419: Properties of each product. Id Name SBO M decdpr tb c decaprenylphosphoryl-beta-D-5-phosphoribose M ppi c Diphosphate

Kinetic Law

v207 = not speciﬁed (414)

266 Produced by SBML2LATEX 6.208 Reaction R DCPT2 This is an irreversible reaction of two reactants forming two products.

Name phosphoribose transferase (undecaprenyl phosphate)

Reaction equation M arpp c + M decd tb c −→ M decdpa tb c + M ppi c (415)

Reactants

Table 420: Properties of each reactant. Id Name SBO M arpp c 5-phosphoarabinose pyrophosphate M decd tb c (E,E,E,E,E,E,E,Z,Z) decaprenyl phosphate

Products

Table 421: Properties of each product. Id Name SBO M decdpa tb c decaprenylphosphoryl-beta-D-5-phosphoarabinofuranose M ppi c Diphosphate

Kinetic Law

v208 = not speciﬁed (416)

6.209 Reaction R DCTPD This is an irreversible reaction of three reactants forming two products.

Name dCTP deaminase

Reaction equation M dctp c + M h2o c + M h c −→ M dutp c + M nh4 c (417)

Reactants

Produced by SBML2LATEX 267 Table 422: Properties of each reactant. Id Name SBO M dctp c dCTP M h2o c H2O M h c H+

Products

Table 423: Properties of each product. Id Name SBO M dutp c dUTP M nh4 c Ammonium

Kinetic Law

v209 = not speciﬁed (418)

6.210 Reaction R DCTPD2 This is an irreversible reaction of three reactants forming two products.

Name dCTP deaminase

Reaction equation M ctp c + M h2o c + M h c −→ M nh4 c + M utp c (419)

Reactants

Table 424: Properties of each reactant. Id Name SBO M ctp c CTP M h2o c H2O M h c H+

Products

268 Produced by SBML2LATEX Table 425: Properties of each product. Id Name SBO M nh4 c Ammonium M utp c UTP

Kinetic Law

v210 = not speciﬁed (420)

6.211 Reaction R DCYTD This is an irreversible reaction of three reactants forming two products.

Name deoxycytidine deaminase

Reaction equation M dcyt c + M h2o c + M h c −→ M duri c + M nh4 c (421)

Reactants

Table 426: Properties of each reactant. Id Name SBO M dcyt c Deoxycytidine M h2o c H2O M h c H+

Products

Table 427: Properties of each product. Id Name SBO M duri c Deoxyuridine M nh4 c Ammonium

Kinetic Law

v211 = not speciﬁed (422)

Produced by SBML2LATEX 269 6.212 Reaction R DDPA This is an irreversible reaction of three reactants forming two products.

Name 3-deoxy-D-arabino-heptulosonate 7-phosphate synthetase

Reaction equation M e4p c + M h2o c + M pep c −→ M 2dda7p c + M pi c (423)

Reactants

Table 428: Properties of each reactant. Id Name SBO M e4p c D-Erythrose 4-phosphate M h2o c H2O M pep c Phosphoenolpyruvate

Products

Table 429: Properties of each product. Id Name SBO M 2dda7p c 2-Dehydro-3-deoxy-D-arabino-heptonate 7-phosphate M pi c Phosphate

Kinetic Law

v212 = not speciﬁed (424)

6.213 Reaction R DESAT16 This is an irreversible reaction of four reactants forming three products.

Name Palmitoyl-CoA desaturase (n-C16:0CoA -> n-C16:1CoA)

Reaction equation M h c + M nadph c + M o2 c + M pmtcoa c −→ 2M h2o c + M hdcoa c + M nadp c (425)

Reactants

270 Produced by SBML2LATEX Table 430: Properties of each reactant. Id Name SBO M h c H+ M nadph c Nicotinamide adenine dinucleotide phosphate - reduced M o2 c O2 M pmtcoa c Palmitoyl-CoA (n-C16:0CoA)

Products

Table 431: Properties of each product. Id Name SBO M h2o c H2O M hdcoa c Hexadecenoyl-CoA (n-C16:1CoA) M nadp c Nicotinamide adenine dinucleotide phosphate

Kinetic Law

v213 = not speciﬁed (426)

6.214 Reaction R DESAT18 This is an irreversible reaction of four reactants forming three products.

Name stearoyl-CoA desaturase (n-C18:0CoA -> n-C18:1CoA)

Reaction equation M h c + M nadph c + M o2 c + M stcoa c −→ 2M h2o c + M nadp c + M odecoa c (427)

Reactants

Table 432: Properties of each reactant. Id Name SBO M h c H+ M nadph c Nicotinamide adenine dinucleotide phosphate - reduced M o2 c O2 M stcoa c Stearoyl-CoA (n-C18:0CoA)

Produced by SBML2LATEX 271 Products

Table 433: Properties of each product. Id Name SBO M h2o c H2O M nadp c Nicotinamide adenine dinucleotide phosphate M odecoa c Octadecenoyl-CoA (n-C18:1CoA)

Kinetic Law

v214 = not speciﬁed (428)

6.215 Reaction R DGC3D This is an irreversible reaction of two reactants forming three products.

Name 2-deoxy-D-gluconate 3-dehydrogenase

Reaction equation M 2dglcn c + M nad c −→ M 3ddgc c + M h c + M nadh c (429)

Reactants

Table 434: Properties of each reactant. Id Name SBO M 2dglcn c 2-Deoxy-D-gluconate M nad c Nicotinamide adenine dinucleotide

Products

Table 435: Properties of each product. Id Name SBO M 3ddgc c 3-Dehydro-2-deoxy-D-gluconate M h c H+ M nadh c Nicotinamide adenine dinucleotide - reduced

272 Produced by SBML2LATEX Kinetic Law

v215 = not speciﬁed (430)

6.216 Reaction R DGK1 This is a reversible reaction of two reactants forming two products.

Name deoxyguanylate kinase (dGMP:ATP)

Reaction equation M atp c + M dgmp c )−−−−* M adp c + M dgdp c (431)

Reactants

Table 436: Properties of each reactant. Id Name SBO M atp c ATP M dgmp c dGMP

Products

Table 437: Properties of each product. Id Name SBO M adp c ADP M dgdp c dGDP

Kinetic Law

v216 = not speciﬁed (432)

6.217 Reaction R DHAD1 This is an irreversible reaction of one reactant forming two products.

Name dihydroxy-acid dehydratase (2,3-dihydroxy-3-methylbutanoate)

Reaction equation M 23dhmb c −→ M 3mob c + M h2o c (433)

Produced by SBML2LATEX 273 Reactant

Table 438: Properties of each reactant. Id Name SBO M 23dhmb c (R)-2,3-Dihydroxy-3-methylbutanoate

Products

Table 439: Properties of each product. Id Name SBO M 3mob c 3-Methyl-2-oxobutanoate M h2o c H2O

Kinetic Law

v217 = not speciﬁed (434)

6.218 Reaction R DHAD2 This is an irreversible reaction of one reactant forming two products.

Name Dihydroxy-acid dehydratase (2,3-dihydroxy-3-methylpentanoate)

Reaction equation M 23dhmp c −→ M 3mop c + M h2o c (435)

Reactant

Table 440: Properties of each reactant. Id Name SBO M 23dhmp c (R)-2,3-Dihydroxy-3-methylpentanoate

Products

274 Produced by SBML2LATEX Table 441: Properties of each product. Id Name SBO M 3mop c (S)-3-Methyl-2-oxopentanoate M h2o c H2O

Kinetic Law

v218 = not speciﬁed (436)

6.219 Reaction R DHDPRy This is an irreversible reaction of three reactants forming two products.

Name dihydrodipicolinate reductase (NADPH)

Reaction equation M 23dhdp c + M h c + M nadph c −→ M nadp c + M thdp c (437)

Reactants

Table 442: Properties of each reactant. Id Name SBO M 23dhdp c 2,3-Dihydrodipicolinate M h c H+ M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

Products

Table 443: Properties of each product. Id Name SBO M nadp c Nicotinamide adenine dinucleotide phosphate M thdp c 2,3,4,5-Tetrahydrodipicolinate

Kinetic Law

v219 = not speciﬁed (438)

Produced by SBML2LATEX 275 6.220 Reaction R DHDPS This is an irreversible reaction of two reactants forming three products.

Name dihydrodipicolinate synthase

Reaction equation M aspsa c + M pyr c −→ M 23dhdp c + 2M h2o c + M h c (439)

Reactants

Table 444: Properties of each reactant. Id Name SBO M aspsa c L-Aspartate 4-semialdehyde M pyr c Pyruvate

Products

Table 445: Properties of each product. Id Name SBO M 23dhdp c 2,3-Dihydrodipicolinate M h2o c H2O M h c H+

Kinetic Law

v220 = not speciﬁed (440)

6.221 Reaction R DHFR This is a reversible reaction of three reactants forming two products.

Name dihydrofolate reductase

Reaction equation M dhf c + M h c + M nadph c )−−−−* M nadp c + M thf c (441)

Reactants

276 Produced by SBML2LATEX Table 446: Properties of each reactant. Id Name SBO M dhf c 7,8-Dihydrofolate M h c H+ M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

Products

Table 447: Properties of each product. Id Name SBO M nadp c Nicotinamide adenine dinucleotide phosphate M thf c 5,6,7,8-Tetrahydrofolate

Kinetic Law

v221 = not speciﬁed (442)

6.222 Reaction R DHFS This is an irreversible reaction of three reactants forming four products.

Name dihydrofolate synthase

Reaction equation M atp c + M dhpt c + M glu DASH L c −→ M adp c + M dhf c + M h c + M pi c (443)

Reactants

Table 448: Properties of each reactant. Id Name SBO M atp c ATP M dhpt c Dihydropteroate M glu DASH L c L-Glutamate

Products

Produced by SBML2LATEX 277 Table 449: Properties of each product. Id Name SBO M adp c ADP M dhf c 7,8-Dihydrofolate M h c H+ M pi c Phosphate

Kinetic Law

v222 = not speciﬁed (444)

6.223 Reaction R DHNAOT This is an irreversible reaction of two reactants forming four products.

Name 1,4-dihydroxy-2-naphthoate octaprenyltransferase

Reaction equation M dhna c + M octdp c −→ M 2dmmq8 c + M co2 c + M h c + M ppi c (445)

Reactants

Table 450: Properties of each reactant. Id Name SBO M dhna c 1,4-Dihydroxy-2-naphthoate M octdp c all-trans-Octaprenyl diphosphate

Products

Table 451: Properties of each product. Id Name SBO M 2dmmq8 c 2-Demethylmenaquinone 8 M co2 c CO2 M h c H+ M ppi c Diphosphate

278 Produced by SBML2LATEX Kinetic Law

v223 = not speciﬁed (446)

6.224 Reaction R DHNAOT2 This is an irreversible reaction of two reactants forming four products.

Name 1,4-dihydroxy-2-naphthoate octaprenyltransferase

Reaction equation M dhna c + M octdp c −→ M 2dmmq6 c + M co2 c + M h c + M ppi c (447)

Reactants

Table 452: Properties of each reactant. Id Name SBO M dhna c 1,4-Dihydroxy-2-naphthoate M octdp c all-trans-Octaprenyl diphosphate

Products

Table 453: Properties of each product. Id Name SBO M 2dmmq6 c 2-Demethylmenaquinone 6 M co2 c CO2 M h c H+ M ppi c Diphosphate

Kinetic Law

v224 = not speciﬁed (448)

6.225 Reaction R DHNPA

This is an irreversible reaction of one reactant forming three products.

Name dihydroneopterin aldolase

Produced by SBML2LATEX 279 Reaction equation M dhnpt c −→ M 2ahhmp c + M gcald c + M h c (449)

Reactant

Table 454: Properties of each reactant. Id Name SBO M dhnpt c Dihydroneopterin

Products

Table 455: Properties of each product. Id Name SBO M 2ahhmp c 2-Amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine M gcald c Glycolaldehyde M h c H+

Kinetic Law

v225 = not speciﬁed (450)

6.226 Reaction R DHNPA2 This is an irreversible reaction of one reactant forming two products.

Name dihydroneopterin aldolase

Reaction equation M dhnpt c −→ M 6hmhpt c + M gcald c (451)

Reactant

Table 456: Properties of each reactant. Id Name SBO M dhnpt c Dihydroneopterin

280 Produced by SBML2LATEX Products

Table 457: Properties of each product. Id Name SBO M 6hmhpt c 6-hydroxymethyl dihydropterin M gcald c Glycolaldehyde

Kinetic Law

v226 = not speciﬁed (452)

6.227 Reaction R DHORD2 This is an irreversible reaction of two reactants forming two products.

Name dihydoorotic acid dehydrogenase (quinone8)

Reaction equation M dhor DASH S c + M q8 c −→ M orot c + M q8h2 c (453)

Reactants

Table 458: Properties of each reactant. Id Name SBO M dhor DASH S c (S)-Dihydroorotate M q8 c Ubiquinone-8

Products

Table 459: Properties of each product. Id Name SBO M orot c Orotate M q8h2 c Ubiquinol-8

Kinetic Law

v227 = not speciﬁed (454)

Produced by SBML2LATEX 281 6.228 Reaction R DHORD3 This is a reversible reaction of two reactants forming two products.

Name dihydroorotic acid dehydrogenase (menaquinone 6)

Reaction equation M dhor DASH S c + M mqn6 c )−−−−* M mql6 c + M orot c (455)

Reactants

Table 460: Properties of each reactant. Id Name SBO M dhor DASH S c (S)-Dihydroorotate M mqn6 c Menaquinone 6

Products

Table 461: Properties of each product. Id Name SBO M mql6 c Menaquinol 6 M orot c Orotate

Kinetic Law

v228 = not speciﬁed (456)

6.229 Reaction R DHORD5 This is an irreversible reaction of two reactants forming two products.

Name dihydroorotic acid (menaquinone-8)

Reaction equation M dhor DASH S c + M mqn8 c −→ M mql8 c + M orot c (457)

Reactants

282 Produced by SBML2LATEX Table 462: Properties of each reactant. Id Name SBO M dhor DASH S c (S)-Dihydroorotate M mqn8 c Menaquinone 8

Products

Table 463: Properties of each product. Id Name SBO M mql8 c Menaquinol 8 M orot c Orotate

Kinetic Law

v229 = not speciﬁed (458)

6.230 Reaction R DHORTS This is a reversible reaction of two reactants forming two products.

Name dihydroorotase

Reaction equation M dhor DASH S c + M h2o c )−−−−* M cbasp c + M h c (459)

Reactants

Table 464: Properties of each reactant. Id Name SBO M dhor DASH S c (S)-Dihydroorotate M h2o c H2O

Products

Table 465: Properties of each product. Id Name SBO M cbasp c N-Carbamoyl-L-aspartate

Produced by SBML2LATEX 283 Id Name SBO M h c H+

Kinetic Law

v230 = not speciﬁed (460)

6.231 Reaction R DHPPDA This is an irreversible reaction of three reactants forming two products.

Name diaminohydroxyphosphoribosylaminopyrimidine deaminase

Reaction equation M 25dhpp c + M h2o c + M h c −→ M 5apru c + M nh4 c (461)

Reactants

Table 466: Properties of each reactant. Id Name SBO M 25dhpp c 2,5-Diamino-6-hydroxy-4-(5’-phosphoribosylamino)-pyrimidine M h2o c H2O M h c H+

Products

Table 467: Properties of each product. Id Name SBO M 5apru c 5-Amino-6-(5’-phosphoribosylamino)uracil M nh4 c Ammonium

Kinetic Law

v231 = not speciﬁed (462)

6.232 Reaction R DHPPDA2 This is an irreversible reaction of three reactants forming two products. Name diaminohydroxyphosphoribosylaminopryrimidine deaminase (25drapp)

284 Produced by SBML2LATEX Reaction equation M 25drapp c + M h2o c + M h c −→ M 5apru c + M nh4 c (463)

Reactants

Table 468: Properties of each reactant. Id Name SBO M 25drapp c 2,5-Diamino-6-(ribosylamino)-4-(3H)-pyrimidinone 5’-phosphate M h2o c H2O M h c H+

Products

Table 469: Properties of each product. Id Name SBO M 5apru c 5-Amino-6-(5’-phosphoribosylamino)uracil M nh4 c Ammonium

Kinetic Law

v232 = not speciﬁed (464)

6.233 Reaction R DHPS2 This is an irreversible reaction of two reactants forming two products.

Name dihydropteroate synthase

Reaction equation M 4abz c + M 6hmhptpp c −→ M dhpt c + M ppi c (465)

Reactants

Table 470: Properties of each reactant. Id Name SBO M 4abz c 4-Aminobenzoate M 6hmhptpp c 6-hydroxymethyl-dihydropterin pyrophosphate

Produced by SBML2LATEX 285 Products

Table 471: Properties of each product. Id Name SBO M dhpt c Dihydropteroate M ppi c Diphosphate

Kinetic Law

v233 = not speciﬁed (466)

6.234 Reaction R DHQD This is a reversible reaction of one reactant forming two products.

Name 3-dehydroquinate dehydratase

Reaction equation M 3dhq c )−−−−* M 3dhsk c + M h2o c (467)

Reactant

Table 472: Properties of each reactant. Id Name SBO M 3dhq c 3-Dehydroquinate

Products

Table 473: Properties of each product. Id Name SBO M 3dhsk c 3-Dehydroshikimate M h2o c H2O

Kinetic Law

v234 = not speciﬁed (468)

286 Produced by SBML2LATEX 6.235 Reaction R DHQS This is an irreversible reaction of one reactant forming two products.

Name 3-dehydroquinate synthase

Reaction equation M 2dda7p c −→ M 3dhq c + M pi c (469)

Reactant

Table 474: Properties of each reactant. Id Name SBO M 2dda7p c 2-Dehydro-3-deoxy-D-arabino-heptonate 7-phosphate

Products

Table 475: Properties of each product. Id Name SBO M 3dhq c 3-Dehydroquinate M pi c Phosphate

Kinetic Law

v235 = not speciﬁed (470)

6.236 Reaction R DMATT This is an irreversible reaction of two reactants forming two products.

Name dimethylallyltranstransferase

Reaction equation M dmpp c + M ipdp c −→ M grdp c + M ppi c (471)

Reactants

Produced by SBML2LATEX 287 Table 476: Properties of each reactant. Id Name SBO M dmpp c Dimethylallyl diphosphate M ipdp c Isopentenyl diphosphate

Products

Table 477: Properties of each product. Id Name SBO M grdp c Geranyl diphosphate M ppi c Diphosphate

Kinetic Law

v236 = not speciﬁed (472)

6.237 Reaction R DMPPS This is an irreversible reaction of three reactants forming three products.

Name 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase (dmpp)

Reaction equation M h2mb4p c + M h c + M nadh c −→ M dmpp c + M h2o c + M nad c (473)

Reactants

Table 478: Properties of each reactant. Id Name SBO M h2mb4p c 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate M h c H+ M nadh c Nicotinamide adenine dinucleotide - reduced

Products

288 Produced by SBML2LATEX Table 479: Properties of each product. Id Name SBO M dmpp c Dimethylallyl diphosphate M h2o c H2O M nad c Nicotinamide adenine dinucleotide

Kinetic Law

v237 = not speciﬁed (474)

6.238 Reaction R DM atp c This is an irreversible reaction of one reactant forming no product.

Name atp demand

Reaction equation M atp c −→ /0 (475)

Reactant

Table 480: Properties of each reactant. Id Name SBO M atp c ATP

Kinetic Law

v238 = not speciﬁed (476)

6.239 Reaction R DNMPPA This is an irreversible reaction of two reactants forming two products.

Name Dihydroneopterin monophosphate dephosphorylase

Reaction equation M dhpmp c + M h2o c −→ M dhnpt c + M pi c (477)

Reactants

Produced by SBML2LATEX 289 Table 481: Properties of each reactant. Id Name SBO M dhpmp c Dihydroneopterin monophosphate M h2o c H2O

Products

Table 482: Properties of each product. Id Name SBO M dhnpt c Dihydroneopterin M pi c Phosphate

Kinetic Law

v239 = not speciﬁed (478)

6.240 Reaction R DNTPPA This is an irreversible reaction of two reactants forming three products.

Name Dihydroneopterin triphosphate pyrophosphatase

Reaction equation M ahdt c + M h2o c −→ M dhpmp c + M h c + M ppi c (479)

Reactants

Table 483: Properties of each reactant. Id Name SBO M ahdt c 2-Amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)dihydropteridine triphosphate M h2o c H2O

Products

Table 484: Properties of each product. Id Name SBO M dhpmp c Dihydroneopterin monophosphate

290 Produced by SBML2LATEX Id Name SBO M h c H+ M ppi c Diphosphate

Kinetic Law

v240 = not speciﬁed (480)

6.241 Reaction R DPCOAK This is an irreversible reaction of two reactants forming three products.

Name dephospho-CoA kinase

Reaction equation M atp c + M dpcoa c −→ M adp c + M coa c + M h c (481)

Reactants

Table 485: Properties of each reactant. Id Name SBO M atp c ATP M dpcoa c Dephospho-CoA

Products

Table 486: Properties of each product. Id Name SBO M adp c ADP M coa c Coenzyme A M h c H+

Kinetic Law

v241 = not speciﬁed (482)

6.242 Reaction R DPPS This is an irreversible reaction of two reactants forming two products.

Produced by SBML2LATEX 291 Name decaprenyl synthase

Reaction equation M frdp c + 7M ipdp c −→ M decdp c + 7M ppi c (483)

Reactants

Table 487: Properties of each reactant. Id Name SBO M frdp c Farnesyl diphosphate M ipdp c Isopentenyl diphosphate

Products

Table 488: Properties of each product. Id Name SBO M decdp c all trans Decaprenyl diphosphate M ppi c Diphosphate

Kinetic Law

v242 = not speciﬁed (484)

6.243 Reaction R DPR This is an irreversible reaction of three reactants forming two products.

Name 2-dehydropantoate 2-reductase

Reaction equation M 2dhp c + M h c + M nadph c −→ M nadp c + M pant DASH R c (485)

Reactants

Table 489: Properties of each reactant. Id Name SBO M 2dhp c 2-Dehydropantoate

292 Produced by SBML2LATEX Id Name SBO M h c H+ M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

Products

Table 490: Properties of each product. Id Name SBO M nadp c Nicotinamide adenine dinucleotide phosphate M pant DASH R c (R)-Pantoate

Kinetic Law

v243 = not speciﬁed (486)

6.244 Reaction R DRPA This is an irreversible reaction of one reactant forming two products.

Name deoxyribose-phosphate aldolase

Reaction equation M 2dr5p c −→ M acald c + M g3p c (487)

Reactant

Table 491: Properties of each reactant. Id Name SBO M 2dr5p c 2-Deoxy-D-ribose 5-phosphate

Products

Table 492: Properties of each product. Id Name SBO M acald c Acetaldehyde M g3p c Glyceraldehyde 3-phosphate

Produced by SBML2LATEX 293 Kinetic Law

v244 = not speciﬁed (488)

6.245 Reaction R DSERt2r This is a reversible reaction of two reactants forming two products.

Name D-serine transport via proton symport

Reaction equation M h e + M ser DASH D e )−−−−* M h c + M ser DASH D c (489)

Reactants

Table 493: Properties of each reactant. Id Name SBO M h e H+ M ser DASH D e D-Serine

Products

Table 494: Properties of each product. Id Name SBO M h c H+ M ser DASH D c D-Serine

Kinetic Law

v245 = not speciﬁed (490)

6.246 Reaction R DTMPK This is a reversible reaction of two reactants forming two products.

Name dTMP kinase

Reaction equation

M atp c + M dtmp c )−−−−* M adp c + M dtdp c (491)

294 Produced by SBML2LATEX Reactants

Table 495: Properties of each reactant. Id Name SBO M atp c ATP M dtmp c dTMP

Products

Table 496: Properties of each product. Id Name SBO M adp c ADP M dtdp c dTDP

Kinetic Law

v246 = not speciﬁed (492)

6.247 Reaction R DURIK1 This is an irreversible reaction of two reactants forming three products.

Name deoxyuridine kinase (ATP:Deoxyuridine)

Reaction equation M atp c + M duri c −→ M adp c + M dump c + M h c (493)

Reactants

Table 497: Properties of each reactant. Id Name SBO M atp c ATP M duri c Deoxyuridine

Products

Produced by SBML2LATEX 295 Table 498: Properties of each product. Id Name SBO M adp c ADP M dump c dUMP M h c H+

Kinetic Law

v247 = not speciﬁed (494)

6.248 Reaction R DURIPP This is a reversible reaction of two reactants forming two products.

Name deoxyuridine phosphorylase

Reaction equation M duri c + M pi c )−−−−* M 2dr1p c + M ura c (495)

Reactants

Table 499: Properties of each reactant. Id Name SBO M duri c Deoxyuridine M pi c Phosphate

Products

Table 500: Properties of each product. Id Name SBO M 2dr1p c 2-Deoxy-D-ribose 1-phosphate M ura c Uracil

Kinetic Law

v248 = not speciﬁed (496)

296 Produced by SBML2LATEX 6.249 Reaction R DUTPDP This is an irreversible reaction of two reactants forming three products.

Name dUTP diphosphatase

Reaction equation M dutp c + M h2o c −→ M dump c + M h c + M ppi c (497)

Reactants

Table 501: Properties of each reactant. Id Name SBO M dutp c dUTP M h2o c H2O

Products

Table 502: Properties of each product. Id Name SBO M dump c dUMP M h c H+ M ppi c Diphosphate

Kinetic Law

v249 = not speciﬁed (498)

6.250 Reaction R DXPRIi This is an irreversible reaction of three reactants forming two products.

Name 1-deoxy-D-xylulose reductoisomerase

Reaction equation M dxyl5p c + M h c + M nadph c −→ M 2me4p c + M nadp c (499)

Reactants

Produced by SBML2LATEX 297 Table 503: Properties of each reactant. Id Name SBO M dxyl5p c 1-deoxy-D-xylulose 5-phosphate M h c H+ M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

Products

Table 504: Properties of each product. Id Name SBO M 2me4p c 2-C-methyl-D-erythritol 4-phosphate M nadp c Nicotinamide adenine dinucleotide phosphate

Kinetic Law

v250 = not speciﬁed (500)

6.251 Reaction R DXPS This is an irreversible reaction of three reactants forming two products.

Name 1-deoxy-D-xylulose 5-phosphate synthase

Reaction equation M g3p c + M h c + M pyr c −→ M co2 c + M dxyl5p c (501)

Reactants

Table 505: Properties of each reactant. Id Name SBO M g3p c Glyceraldehyde 3-phosphate M h c H+ M pyr c Pyruvate

Products

298 Produced by SBML2LATEX Table 506: Properties of each product. Id Name SBO M co2 c CO2 M dxyl5p c 1-deoxy-D-xylulose 5-phosphate

Kinetic Law

v251 = not speciﬁed (502)

6.252 Reaction R E4PD This is a reversible reaction of three reactants forming three products.

Name Erythrose 4-phosphate dehydrogenase

Reaction equation M e4p c + M h2o c + M nad c )−−−−* M 4per c + 2M h c + M nadh c (503)

Reactants

Table 507: Properties of each reactant. Id Name SBO M e4p c D-Erythrose 4-phosphate M h2o c H2O M nad c Nicotinamide adenine dinucleotide

Products

Table 508: Properties of each product. Id Name SBO M 4per c 4-Phospho-D-erythronate M h c H+ M nadh c Nicotinamide adenine dinucleotide - reduced

Kinetic Law

v252 = not speciﬁed (504)

Produced by SBML2LATEX 299 6.253 Reaction R ECHH 0 This is a reversible reaction of two reactants forming two products.

Name Ech hydrogenase (no electron transport)

Reaction equation 2M fdox c + M h2 c )−−−−* 2M fdred c + 2M h c (505)

Reactants

Table 509: Properties of each reactant. Id Name SBO M fdox c ferredoxin (oxidized) 2[4Fe-4S] M h2 c H2

Products

Table 510: Properties of each product. Id Name SBO M fdred c ferredoxin (reduced) 2[4Fe-4S] M h c H+

Kinetic Law

v253 = not speciﬁed (506)

6.254 Reaction R ENO This is a reversible reaction of one reactant forming two products.

Name enolase

Reaction equation M 2pg c )−−−−* M h2o c + M pep c (507)

Reactant

300 Produced by SBML2LATEX Table 511: Properties of each reactant. Id Name SBO M 2pg c D-Glycerate 2-phosphate

Products

Table 512: Properties of each product. Id Name SBO M h2o c H2O M pep c Phosphoenolpyruvate

Kinetic Law

v254 = not speciﬁed (508)

6.255 Reaction R ENTCS This is an irreversible reaction of two reactants forming three products.

Name enterochelin synthase

Reaction equation 3M 23dhba c + 3M seramp c −→ 6M amp c + M enter c + 9M h c (509)

Reactants

Table 513: Properties of each reactant. Id Name SBO M 23dhba c (2,3-Dihydroxybenzoyl)adenylate M seramp c L-seryl-AMP

Products

Table 514: Properties of each product. Id Name SBO M amp c AMP M enter c Enterochelin

Produced by SBML2LATEX 301 Id Name SBO M h c H+

Kinetic Law

v255 = not speciﬁed (510)

6.256 Reaction R ETHAt This is a reversible reaction of one reactant forming one product.

Name ethanolamine transport via diffusion (extracellular)

Reaction equation M etha e )−−−−* M etha c (511)

Reactant

Table 515: Properties of each reactant. Id Name SBO M etha e Ethanolamine

Product

Table 516: Properties of each product. Id Name SBO M etha c Ethanolamine

Kinetic Law

v256 = not speciﬁed (512)

6.257 Reaction R EX acysbmn e

This is an irreversible reaction of one reactant forming no product.

Name acetyl-cystine-bimane exchange

302 Produced by SBML2LATEX Reaction equation M acysbmn e −→ /0 (513)

Reactant

Table 517: Properties of each reactant. Id Name SBO M acysbmn e acetyl-cystine-bimane

Kinetic Law

v257 = not speciﬁed (514)

6.258 Reaction R EX ala DASH B e This is an irreversible reaction of one reactant forming no product.

Name beta-Alanine exchange

Reaction equation M ala DASH B e −→ /0 (515)

Reactant

Table 518: Properties of each reactant. Id Name SBO M ala DASH B e beta-Alanine

Kinetic Law

v258 = not speciﬁed (516)

6.259 Reaction R EX ala DASH D e This is an irreversible reaction of one reactant forming no product. Name D-Alanine exchange

Reaction equation M ala DASH D e −→ /0 (517)

Produced by SBML2LATEX 303 Reactant

Table 519: Properties of each reactant. Id Name SBO M ala DASH D e D-Alanine

Kinetic Law

v259 = not speciﬁed (518)

6.260 Reaction R EX ala DASH L e This is an irreversible reaction of one reactant forming no product.

Name L-Alanine exchange

Reaction equation M ala DASH L e −→ /0 (519)

Reactant

Table 520: Properties of each reactant. Id Name SBO M ala DASH L e L-Alanine

Kinetic Law

v260 = not speciﬁed (520)

6.261 Reaction R EX arab DASH D e This is an irreversible reaction of one reactant forming no product. Name D-Arabinose exchange

Reaction equation M arab DASH D e −→ /0 (521)

Reactant

304 Produced by SBML2LATEX Table 521: Properties of each reactant. Id Name SBO M arab DASH D e D-Arabinose

Kinetic Law

v261 = not speciﬁed (522)

6.262 Reaction R EX arab DASH L e This is an irreversible reaction of one reactant forming no product.

Name L-Arabinose exchange

Reaction equation M arab DASH L e −→ /0 (523)

Reactant

Table 522: Properties of each reactant. Id Name SBO M arab DASH L e L-Arabinose

Kinetic Law

v262 = not speciﬁed (524)

6.263 Reaction R EX arg DASH L e This is an irreversible reaction of one reactant forming no product.

Name L-Arginine exchange

Reaction equation M arg DASH L e −→ /0 (525)

Reactant

Produced by SBML2LATEX 305 Table 523: Properties of each reactant. Id Name SBO M arg DASH L e L-Arginine

Kinetic Law

v263 = not speciﬁed (526)

6.264 Reaction R EX asn DASH L e This is an irreversible reaction of one reactant forming no product.

Name L-Asparagine exchange

Reaction equation M asn DASH L e −→ /0 (527)

Reactant

Table 524: Properties of each reactant. Id Name SBO M asn DASH L e L-Asparagine

Kinetic Law

v264 = not speciﬁed (528)

6.265 Reaction R EX asp DASH L e This is an irreversible reaction of one reactant forming no product.

Name L-Aspartate exchange

Reaction equation M asp DASH L e −→ /0 (529)

Reactant

306 Produced by SBML2LATEX Table 525: Properties of each reactant. Id Name SBO M asp DASH L e L-Aspartate

Kinetic Law

v265 = not speciﬁed (530)

6.266 Reaction R EX atp e This is an irreversible reaction of one reactant forming no product.

Name ATP exchange

Reaction equation M atp e −→ /0 (531)

Reactant

Table 526: Properties of each reactant. Id Name SBO M atp e ATP

Kinetic Law

v266 = not speciﬁed (532)

6.267 Reaction R EX bmn e This is an irreversible reaction of one reactant forming no product.

Name bimane exchange

Reaction equation M bmn e −→ /0 (533)

Reactant

Produced by SBML2LATEX 307 Table 527: Properties of each reactant. Id Name SBO M bmn e bimane

Kinetic Law

v267 = not speciﬁed (534)

6.268 Reaction R EX ca2 e This is a reversible reaction of one reactant forming no product.

Name Calcium exchange

Reaction equation M ca2 e )−−−−* /0 (535)

Reactant

Table 528: Properties of each reactant. Id Name SBO M ca2 e Calcium

Kinetic Law

v268 = not speciﬁed (536)

6.269 Reaction R EX chol e This is an irreversible reaction of one reactant forming no product.

Name Choline exchange

Reaction equation M chol e −→ /0 (537)

Reactant

308 Produced by SBML2LATEX Table 529: Properties of each reactant. Id Name SBO M chol e Choline

Kinetic Law

v269 = not speciﬁed (538)

6.270 Reaction R EX cit e This is a reversible reaction of one reactant forming no product.

Name Citrate exchange

Reaction equation M cit e )−−−−* /0 (539)

Reactant

Table 530: Properties of each reactant. Id Name SBO M cit e Citrate

Kinetic Law

v270 = not speciﬁed (540)

6.271 Reaction R EX cl e This is a reversible reaction of one reactant forming no product.

Name Chloride exchange

Reaction equation M cl e )−−−−* /0 (541)

Reactant

Produced by SBML2LATEX 309 Table 531: Properties of each reactant. Id Name SBO M cl e Chloride

Kinetic Law

v271 = not speciﬁed (542)

6.272 Reaction R EX co2 e This is an irreversible reaction of one reactant forming no product.

Name CO2 exchange

Reaction equation M co2 e −→ /0 (543)

Reactant

Table 532: Properties of each reactant. Id Name SBO M co2 e CO2

Kinetic Law

v272 = not speciﬁed (544)

6.273 Reaction R EX co e This is an irreversible reaction of one reactant forming no product.

Name Carbon monoxide exchange

Reaction equation M co e −→ /0 (545)

Reactant

310 Produced by SBML2LATEX Table 533: Properties of each reactant. Id Name SBO M co e Carbon monoxide

Kinetic Law

v273 = not speciﬁed (546)

6.274 Reaction R EX coa e This is an irreversible reaction of one reactant forming no product.

Name Coenzyme A exchange

Reaction equation M coa e −→ /0 (547)

Reactant

Table 534: Properties of each reactant. Id Name SBO M coa e Coenzyme A

Kinetic Law

v274 = not speciﬁed (548)

6.275 Reaction R EX cobalt2 e This is an irreversible reaction of one reactant forming no product.

Name Co2+ exchange

Reaction equation M cobalt2 e −→ /0 (549)

Reactant

Produced by SBML2LATEX 311 Table 535: Properties of each reactant. Id Name SBO M cobalt2 e Co2+

Kinetic Law

v275 = not speciﬁed (550)

6.276 Reaction R EX crn e This is an irreversible reaction of one reactant forming no product.

Name L-Carnitine exchange

Reaction equation M crn e −→ /0 (551)

Reactant

Table 536: Properties of each reactant. Id Name SBO M crn e L-Carnitine

Kinetic Law

v276 = not speciﬁed (552)

6.277 Reaction R EX cu2 e This is a reversible reaction of one reactant forming no product.

Name Cu2+ exchange

Reaction equation M cu2 e )−−−−* /0 (553)

Reactant

312 Produced by SBML2LATEX Table 537: Properties of each reactant. Id Name SBO M cu2 e Cu2+

Kinetic Law

v277 = not speciﬁed (554)

6.278 Reaction R EX cytd e This is an irreversible reaction of one reactant forming no product.

Name Cytidine exchange

Reaction equation M cytd e −→ /0 (555)

Reactant

Table 538: Properties of each reactant. Id Name SBO M cytd e Cytidine

Kinetic Law

v278 = not speciﬁed (556)

6.279 Reaction R EX etha e This is an irreversible reaction of one reactant forming no product.

Name Ethanolamine exchange

Reaction equation M etha e −→ /0 (557)

Reactant

Produced by SBML2LATEX 313 Table 539: Properties of each reactant. Id Name SBO M etha e Ethanolamine

Kinetic Law

v279 = not speciﬁed (558)

6.280 Reaction R EX fe2 e This is an irreversible reaction of one reactant forming no product.

Name Fe2+ exchange

Reaction equation M fe2 e −→ /0 (559)

Reactant

Table 540: Properties of each reactant. Id Name SBO M fe2 e Fe2+

Kinetic Law

v280 = not speciﬁed (560)

6.281 Reaction R EX fe3 e This is a reversible reaction of one reactant forming no product.

Name Fe3+ exchange

Reaction equation M fe3 e )−−−−* /0 (561)

Reactant

314 Produced by SBML2LATEX Table 541: Properties of each reactant. Id Name SBO M fe3 e Fe3+

Kinetic Law

v281 = not speciﬁed (562)

6.282 Reaction R EX fum e This is an irreversible reaction of one reactant forming no product.

Name Fumarate exchange

Reaction equation M fum e −→ /0 (563)

Reactant

Table 542: Properties of each reactant. Id Name SBO M fum e Fumarate

Kinetic Law

v282 = not speciﬁed (564)

6.283 Reaction R EX gal e This is an irreversible reaction of one reactant forming no product.

Name D-Galactose exchange

Reaction equation M gal e −→ /0 (565)

Reactant

Produced by SBML2LATEX 315 Table 543: Properties of each reactant. Id Name SBO M gal e D-Galactose

Kinetic Law

v283 = not speciﬁed (566)

6.284 Reaction R EX glc DASH D e This is a reversible reaction of one reactant forming no product.

Name D-Glucose exchange

Reaction equation M glc DASH D e )−−−−* /0 (567)

Reactant

Table 544: Properties of each reactant. Id Name SBO M glc DASH D e D-Glucose

Kinetic Law

v284 = not speciﬁed (568)

6.285 Reaction R EX glu DASH L e This is a reversible reaction of one reactant forming no product.

Name L-Glutamate exchange

Reaction equation M glu DASH L e )−−−−* /0 (569)

Reactant

316 Produced by SBML2LATEX Table 545: Properties of each reactant. Id Name SBO M glu DASH L e L-Glutamate

Kinetic Law

v285 = not speciﬁed (570)

6.286 Reaction R EX gly e This is an irreversible reaction of one reactant forming no product.

Name Glycine exchange

Reaction equation M gly e −→ /0 (571)

Reactant

Table 546: Properties of each reactant. Id Name SBO M gly e Glycine

Kinetic Law

v286 = not speciﬁed (572)

6.287 Reaction R EX glyb e This is an irreversible reaction of one reactant forming no product.

Name Glycine betaine exchange

Reaction equation M glyb e −→ /0 (573)

Reactant

Produced by SBML2LATEX 317 Table 547: Properties of each reactant. Id Name SBO M glyb e Glycine betaine

Kinetic Law

v287 = not speciﬁed (574)

6.288 Reaction R EX glyc3p e This is an irreversible reaction of one reactant forming no product.

Name Glycerol 3-phosphate exchange

Reaction equation M glyc3p e −→ /0 (575)

Reactant

Table 548: Properties of each reactant. Id Name SBO M glyc3p e Glycerol 3-phosphate

Kinetic Law

v288 = not speciﬁed (576)

6.289 Reaction R EX glyc e This is a reversible reaction of one reactant forming no product.

Name Glycerol exchange

Reaction equation M glyc e )−−−−* /0 (577)

Reactant

318 Produced by SBML2LATEX Table 549: Properties of each reactant. Id Name SBO M glyc e Glycerol

Kinetic Law

v289 = not speciﬁed (578)

6.290 Reaction R EX gthrd e This is an irreversible reaction of one reactant forming no product.

Name Reduced glutathione exchange

Reaction equation M gthrd e −→ /0 (579)

Reactant

Table 550: Properties of each reactant. Id Name SBO M gthrd e Reduced glutathione

Kinetic Law

v290 = not speciﬁed (580)

6.291 Reaction R EX h2 e This is an irreversible reaction of one reactant forming no product.

Name H2 exchange

Reaction equation M h2 e −→ /0 (581)

Reactant

Produced by SBML2LATEX 319 Table 551: Properties of each reactant. Id Name SBO M h2 e H2

Kinetic Law

v291 = not speciﬁed (582)

6.292 Reaction R EX h2co3 e This is a reversible reaction of one reactant forming no product.

Name carbonic acid exchange

Reaction equation M h2co3 e )−−−−* /0 (583)

Reactant

Table 552: Properties of each reactant. Id Name SBO M h2co3 e carbonic acid

Kinetic Law

v292 = not speciﬁed (584)

6.293 Reaction R EX h2o e This is a reversible reaction of one reactant forming no product.

Name H2O exchange

Reaction equation M h2o e )−−−−* /0 (585)

Reactant

320 Produced by SBML2LATEX Table 553: Properties of each reactant. Id Name SBO M h2o e H2O

Kinetic Law

v293 = not speciﬁed (586)

6.294 Reaction R EX h2s e This is an irreversible reaction of one reactant forming no product.

Name Hydrogen sulﬁde exchange

Reaction equation M h2s e −→ /0 (587)

Reactant

Table 554: Properties of each reactant. Id Name SBO M h2s e Hydrogen sulﬁde

Kinetic Law

v294 = not speciﬁed (588)

6.295 Reaction R EX h e This is a reversible reaction of one reactant forming no product.

Name H+ exchange

Reaction equation M h e )−−−−* /0 (589)

Reactant

Produced by SBML2LATEX 321 Table 555: Properties of each reactant. Id Name SBO M h e H+

Kinetic Law

v295 = not speciﬁed (590)

6.296 Reaction R EX hdca e This is an irreversible reaction of one reactant forming no product.

Name Hexadecanoate (n-C16:0) exchange

Reaction equation M hdca e −→ /0 (591)

Reactant

Table 556: Properties of each reactant. Id Name SBO M hdca e Hexadecanoate (n-C16:0)

Kinetic Law

v296 = not speciﬁed (592)

6.297 Reaction R EX his DASH L e This is an irreversible reaction of one reactant forming no product.

Name L-Histidine exchange

Reaction equation M his DASH L e −→ /0 (593)

Reactant

322 Produced by SBML2LATEX Table 557: Properties of each reactant. Id Name SBO M his DASH L e L-Histidine

Kinetic Law

v297 = not speciﬁed (594)

6.298 Reaction R EX id3acald e This is an irreversible reaction of one reactant forming no product.

Name Indole-3-acetaldehyde exchange

Reaction equation M id3acald e −→ /0 (595)

Reactant

Table 558: Properties of each reactant. Id Name SBO M id3acald e Indole-3-acetaldehyde

Kinetic Law

v298 = not speciﬁed (596)

6.299 Reaction R EX ile DASH L e This is an irreversible reaction of one reactant forming no product.

Name L-Isoleucine exchange

Reaction equation M ile DASH L e −→ /0 (597)

Reactant

Produced by SBML2LATEX 323 Table 559: Properties of each reactant. Id Name SBO M ile DASH L e L-Isoleucine

Kinetic Law

v299 = not speciﬁed (598)

6.300 Reaction R EX k e This is a reversible reaction of one reactant forming no product.

Name K+ exchange

Reaction equation M k e )−−−−* /0 (599)

Reactant

Table 560: Properties of each reactant. Id Name SBO M k e potassium

Kinetic Law

v300 = not speciﬁed (600)

6.301 Reaction R EX lac DASH L e This is an irreversible reaction of one reactant forming no product.

Name L-Lactate exchange

Reaction equation M lac DASH L e −→ /0 (601)

Reactant

324 Produced by SBML2LATEX Table 561: Properties of each reactant. Id Name SBO M lac DASH L e L-Lactate

Kinetic Law

v301 = not speciﬁed (602)

6.302 Reaction R EX lcts e This is an irreversible reaction of one reactant forming no product.

Name Lactose exchange

Reaction equation M lcts e −→ /0 (603)

Reactant

Table 562: Properties of each reactant. Id Name SBO M lcts e Lactose

Kinetic Law

v302 = not speciﬁed (604)

6.303 Reaction R EX leu DASH L e This is an irreversible reaction of one reactant forming no product.

Name L-Leucine exchange

Reaction equation M leu DASH L e −→ /0 (605)

Reactant

Produced by SBML2LATEX 325 Table 563: Properties of each reactant. Id Name SBO M leu DASH L e L-Leucine

Kinetic Law

v303 = not speciﬁed (606)

6.304 Reaction R EX lys DASH L e This is an irreversible reaction of one reactant forming no product.

Name L-Lysine exchange

Reaction equation M lys DASH L e −→ /0 (607)

Reactant

Table 564: Properties of each reactant. Id Name SBO M lys DASH L e L-Lysine

Kinetic Law

v304 = not speciﬁed (608)

6.305 Reaction R EX mal DASH L e This is an irreversible reaction of one reactant forming no product.

Name L-Malate exchange

Reaction equation M mal DASH L e −→ /0 (609)

Reactant

326 Produced by SBML2LATEX Table 565: Properties of each reactant. Id Name SBO M mal DASH L e L-Malate

Kinetic Law

v305 = not speciﬁed (610)

6.306 Reaction R EX malt e This is an irreversible reaction of one reactant forming no product.

Name Maltose exchange

Reaction equation M malt e −→ /0 (611)

Reactant

Table 566: Properties of each reactant. Id Name SBO M malt e Maltose

Kinetic Law

v306 = not speciﬁed (612)

6.307 Reaction R EX malthp e This is an irreversible reaction of one reactant forming no product.

Name Maltoheptaose exchange

Reaction equation M malthp e −→ /0 (613)

Reactant

Produced by SBML2LATEX 327 Table 567: Properties of each reactant. Id Name SBO M malthp e Maltoheptaose

Kinetic Law

v307 = not speciﬁed (614)

6.308 Reaction R EX meoh e This is an irreversible reaction of one reactant forming no product.

Name methanol exchange

Reaction equation M meoh e −→ /0 (615)

Reactant

Table 568: Properties of each reactant. Id Name SBO M meoh e Methanol

Kinetic Law

v308 = not speciﬁed (616)

6.309 Reaction R EX met DASH L e This is an irreversible reaction of one reactant forming no product.

Name L-Methionine exchange

Reaction equation M met DASH L e −→ /0 (617)

Reactant

328 Produced by SBML2LATEX Table 569: Properties of each reactant. Id Name SBO M met DASH L e L-Methionine

Kinetic Law

v309 = not speciﬁed (618)

6.310 Reaction R EX mg2 e This is an irreversible reaction of one reactant forming no product.

Name Mg exchange

Reaction equation M mg2 e −→ /0 (619)

Reactant

Table 570: Properties of each reactant. Id Name SBO M mg2 e magnesium

Kinetic Law

v310 = not speciﬁed (620)

6.311 Reaction R EX na1 e This is a reversible reaction of one reactant forming no product.

Name Sodium exchange

Reaction equation M na1 e )−−−−* /0 (621)

Reactant

Produced by SBML2LATEX 329 Table 571: Properties of each reactant. Id Name SBO M na1 e Sodium

Kinetic Law

v311 = not speciﬁed (622)

6.312 Reaction R EX nh4 e This is a reversible reaction of one reactant forming no product.

Name Ammonia exchange

Reaction equation M nh4 e )−−−−* /0 (623)

Reactant

Table 572: Properties of each reactant. Id Name SBO M nh4 e Ammonium

Kinetic Law

v312 = not speciﬁed (624)

6.313 Reaction R EX no2 e This is an irreversible reaction of one reactant forming no product.

Name Nitrite exchange

Reaction equation M no2 e −→ /0 (625)

Reactant

330 Produced by SBML2LATEX Table 573: Properties of each reactant. Id Name SBO M no2 e Nitrite

Kinetic Law

v313 = not speciﬁed (626)

6.314 Reaction R EX no3 e This is an irreversible reaction of one reactant forming no product.

Name Nitrate exchange

Reaction equation M no3 e −→ /0 (627)

Reactant

Table 574: Properties of each reactant. Id Name SBO M no3 e Nitrate

Kinetic Law

v314 = not speciﬁed (628)

6.315 Reaction R EX no e This is an irreversible reaction of one reactant forming no product.

Name Nitric oxide exchange

Reaction equation M no e −→ /0 (629)

Reactant

Produced by SBML2LATEX 331 Table 575: Properties of each reactant. Id Name SBO M no e Nitric oxide

Kinetic Law

v315 = not speciﬁed (630)

6.316 Reaction R EX o2 e This is a reversible reaction of one reactant forming no product.

Name O2 exchange

Reaction equation M o2 e )−−−−* /0 (631)

Reactant

Table 576: Properties of each reactant. Id Name SBO M o2 e O2

Kinetic Law

v316 = not speciﬁed (632)

6.317 Reaction R EX ocdca e This is an irreversible reaction of one reactant forming no product.

Name octadecanoate (n-C18:0) exchange

Reaction equation M ocdca e −→ /0 (633)

Reactant

332 Produced by SBML2LATEX Table 577: Properties of each reactant. Id Name SBO M ocdca e octadecanoate (n-C18:0)

Kinetic Law

v317 = not speciﬁed (634)

6.318 Reaction R EX orn e This is an irreversible reaction of one reactant forming no product.

Name Ornithine exchange

Reaction equation M orn e −→ /0 (635)

Reactant

Table 578: Properties of each reactant. Id Name SBO M orn e Ornithine

Kinetic Law

v318 = not speciﬁed (636)

6.319 Reaction R EX pac e This is an irreversible reaction of one reactant forming no product.

Name Phenylacetic acid exchange

Reaction equation M pac e −→ /0 (637)

Reactant

Produced by SBML2LATEX 333 Table 579: Properties of each reactant. Id Name SBO M pac e Phenylacetic acid

Kinetic Law

v319 = not speciﬁed (638)

6.320 Reaction R EX pdima e This is an irreversible reaction of one reactant forming no product.

Name phthiocerol dimycocerosate A (Mtb) exchange

Reaction equation M pdima e −→ /0 (639)

Reactant

Table 580: Properties of each reactant. Id Name SBO M pdima e phthiocerol dimycocerosate A (Mtb)

Kinetic Law

v320 = not speciﬁed (640)

6.321 Reaction R EX phdca e This is an irreversible reaction of one reactant forming no product.

Name phenol palmitic acid exchange

Reaction equation M phdca e −→ /0 (641)

Reactant

334 Produced by SBML2LATEX Table 581: Properties of each reactant. Id Name SBO M phdca e phenol palmitic acid

Kinetic Law

v321 = not speciﬁed (642)

6.322 Reaction R EX phe DASH L e This is an irreversible reaction of one reactant forming no product.

Name L-Phenylalanine exchange

Reaction equation M phe DASH L e −→ /0 (643)

Reactant

Table 582: Properties of each reactant. Id Name SBO M phe DASH L e L-Phenylalanine

Kinetic Law

v322 = not speciﬁed (644)

6.323 Reaction R EX pi e This is a reversible reaction of one reactant forming no product.

Name Phosphate exchange

Reaction equation M pi e )−−−−* /0 (645)

Reactant

Produced by SBML2LATEX 335 Table 583: Properties of each reactant. Id Name SBO M pi e Phosphate

Kinetic Law

v323 = not speciﬁed (646)

6.324 Reaction R EX ppa e This is an irreversible reaction of one reactant forming no product.

Name Propionate exchange

Reaction equation M ppa e −→ /0 (647)

Reactant

Table 584: Properties of each reactant. Id Name SBO M ppa e Propionate (n-C3:0)

Kinetic Law

v324 = not speciﬁed (648)

6.325 Reaction R EX ppdima e This is an irreversible reaction of one reactant forming no product.

Name phenol phthiocerol dimycocerosate (Mtb) exchange

Reaction equation M ppdima e −→ /0 (649)

Reactant

336 Produced by SBML2LATEX Table 585: Properties of each reactant. Id Name SBO M ppdima e phenol phthiocerol dimycocerosate (Mtb)

Kinetic Law

v325 = not speciﬁed (650)

6.326 Reaction R EX pro DASH L e This is an irreversible reaction of one reactant forming no product.

Name L-Proline exchange

Reaction equation M pro DASH L e −→ /0 (651)

Reactant

Table 586: Properties of each reactant. Id Name SBO M pro DASH L e L-Proline

Kinetic Law

v326 = not speciﬁed (652)

6.327 Reaction R EX pyr e This is an irreversible reaction of one reactant forming no product.

Name Pyruvate exchange

Reaction equation M pyr e −→ /0 (653)

Reactant

Produced by SBML2LATEX 337 Table 587: Properties of each reactant. Id Name SBO M pyr e Pyruvate

Kinetic Law

v327 = not speciﬁed (654)

6.328 Reaction R EX rib DASH D e This is an irreversible reaction of one reactant forming no product.

Name D-Ribose exchange

Reaction equation M rib DASH D e −→ /0 (655)

Reactant

Table 588: Properties of each reactant. Id Name SBO M rib DASH D e D-Ribose

Kinetic Law

v328 = not speciﬁed (656)

6.329 Reaction R EX ser DASH D e This is an irreversible reaction of one reactant forming no product.

Name D-Serine exchange

Reaction equation M ser DASH D e −→ /0 (657)

Reactant

338 Produced by SBML2LATEX Table 589: Properties of each reactant. Id Name SBO M ser DASH D e D-Serine

Kinetic Law

v329 = not speciﬁed (658)

6.330 Reaction R EX ser DASH L e This is an irreversible reaction of one reactant forming no product.

Name L-Serine exchange

Reaction equation M ser DASH L e −→ /0 (659)

Reactant

Table 590: Properties of each reactant. Id Name SBO M ser DASH L e L-Serine

Kinetic Law

v330 = not speciﬁed (660)

6.331 Reaction R EX skm e This is an irreversible reaction of one reactant forming no product.

Name Shikimate exchange

Reaction equation M skm e −→ /0 (661)

Reactant

Produced by SBML2LATEX 339 Table 591: Properties of each reactant. Id Name SBO M skm e Shikimate

Kinetic Law

v331 = not speciﬁed (662)

6.332 Reaction R EX so4 e This is a reversible reaction of one reactant forming no product.

Name Sulfate exchange

Reaction equation M so4 e )−−−−* /0 (663)

Reactant

Table 592: Properties of each reactant. Id Name SBO M so4 e Sulfate

Kinetic Law

v332 = not speciﬁed (664)

6.333 Reaction R EX succ e This is an irreversible reaction of one reactant forming no product.

Name Succinate exchange

Reaction equation M succ e −→ /0 (665)

Reactant

340 Produced by SBML2LATEX Table 593: Properties of each reactant. Id Name SBO M succ e Succinate

Kinetic Law

v333 = not speciﬁed (666)

6.334 Reaction R EX tartr DASH L e This is an irreversible reaction of one reactant forming no product.

Name L-tartrate exchange

Reaction equation M tartr DASH L e −→ /0 (667)

Reactant

Table 594: Properties of each reactant. Id Name SBO M tartr DASH L e L-tartrate

Kinetic Law

v334 = not speciﬁed (668)

6.335 Reaction R EX thr DASH L e This is an irreversible reaction of one reactant forming no product.

Name L-Threonine exchange

Reaction equation M thr DASH L e −→ /0 (669)

Reactant

Produced by SBML2LATEX 341 Table 595: Properties of each reactant. Id Name SBO M thr DASH L e L-Threonine

Kinetic Law

v335 = not speciﬁed (670)

6.336 Reaction R EX tre e This is an irreversible reaction of one reactant forming no product.

Name Trehalose exchange

Reaction equation M tre e −→ /0 (671)

Reactant

Table 596: Properties of each reactant. Id Name SBO M tre e Trehalose

Kinetic Law

v336 = not speciﬁed (672)

6.337 Reaction R EX trp DASH L e This is an irreversible reaction of one reactant forming no product.

Name L-Tryptophan exchange

Reaction equation M trp DASH L e −→ /0 (673)

Reactant

342 Produced by SBML2LATEX Table 597: Properties of each reactant. Id Name SBO M trp DASH L e L-Tryptophan

Kinetic Law

v337 = not speciﬁed (674)

6.338 Reaction R EX tsul e This is an irreversible reaction of one reactant forming no product.

Name Thiosulfate exchange

Reaction equation M tsul e −→ /0 (675)

Reactant

Table 598: Properties of each reactant. Id Name SBO M tsul e Thiosulfate

Kinetic Law

v338 = not speciﬁed (676)

6.339 Reaction R EX ttdca e This is an irreversible reaction of one reactant forming no product.

Name tetradecanoate (n-C14:0) exchange

Reaction equation M ttdca e −→ /0 (677)

Reactant

Produced by SBML2LATEX 343 Table 599: Properties of each reactant. Id Name SBO M ttdca e tetradecanoate (n-C14:0)

Kinetic Law

v339 = not speciﬁed (678)

6.340 Reaction R EX tyr DASH L e This is an irreversible reaction of one reactant forming no product.

Name L-Tyrosine exchange

Reaction equation M tyr DASH L e −→ /0 (679)

Reactant

Table 600: Properties of each reactant. Id Name SBO M tyr DASH L e L-Tyrosine

Kinetic Law

v340 = not speciﬁed (680)

6.341 Reaction R EX val DASH L e This is an irreversible reaction of one reactant forming no product.

Name L-Valine exchange

Reaction equation M val DASH L e −→ /0 (681)

Reactant

344 Produced by SBML2LATEX Table 601: Properties of each reactant. Id Name SBO M val DASH L e L-Valine

Kinetic Law

v341 = not speciﬁed (682)

6.342 Reaction R EX xyl DASH D e This is an irreversible reaction of one reactant forming no product.

Name D-Xylose exchange

Reaction equation M xyl DASH D e −→ /0 (683)

Reactant

Table 602: Properties of each reactant. Id Name SBO M xyl DASH D e D-Xylose

Kinetic Law

v342 = not speciﬁed (684)

6.343 Reaction R FACOAE140 This is an irreversible reaction of two reactants forming three products.

Name fatty-acid-CoA thioesterase (tetradecanoate)

Reaction equation M h2o c + M tdcoa c −→ M coa c + M h c + M ttdca c (685)

Reactants

Produced by SBML2LATEX 345 Table 603: Properties of each reactant. Id Name SBO M h2o c H2O M tdcoa c Tetradecanoyl-CoA (n-C14:0CoA)

Products

Table 604: Properties of each product. Id Name SBO M coa c Coenzyme A M h c H+ M ttdca c tetradecanoate (n-C14:0)

Kinetic Law

v343 = not speciﬁed (686)

6.344 Reaction R FACOAE160 This is an irreversible reaction of two reactants forming three products.

Name fatty-acid-CoA thioesterase (hexadecanoate)

Reaction equation M h2o c + M pmtcoa c −→ M coa c + M h c + M hdca c (687)

Reactants

Table 605: Properties of each reactant. Id Name SBO M h2o c H2O M pmtcoa c Palmitoyl-CoA (n-C16:0CoA)

Products

346 Produced by SBML2LATEX Table 606: Properties of each product. Id Name SBO M coa c Coenzyme A M h c H+ M hdca c Hexadecanoate (n-C16:0)

Kinetic Law

v344 = not speciﬁed (688)

6.345 Reaction R FACOAE180 This is an irreversible reaction of two reactants forming three products.

Name fatty-acid-CoA thioesterase (octadecanoate)

Reaction equation M h2o c + M stcoa c −→ M coa c + M h c + M ocdca c (689)

Reactants

Table 607: Properties of each reactant. Id Name SBO M h2o c H2O M stcoa c Stearoyl-CoA (n-C18:0CoA)

Products

Table 608: Properties of each product. Id Name SBO M coa c Coenzyme A M h c H+ M ocdca c octadecanoate (n-C18:0)

Kinetic Law

v345 = not speciﬁed (690)

Produced by SBML2LATEX 347 6.346 Reaction R FACOAL140 This is a reversible reaction of three reactants forming three products.

Name fatty-acid–CoA ligase (tetradecanoate)

Reaction equation M atp c + M coa c + M ttdca c )−−−−* M amp c + M ppi c + M tdcoa c (691)

Reactants

Table 609: Properties of each reactant. Id Name SBO M atp c ATP M coa c Coenzyme A M ttdca c tetradecanoate (n-C14:0)

Products

Table 610: Properties of each product. Id Name SBO M amp c AMP M ppi c Diphosphate M tdcoa c Tetradecanoyl-CoA (n-C14:0CoA)

Kinetic Law

v346 = not speciﬁed (692)

6.347 Reaction R FACOAL160 This is a reversible reaction of three reactants forming three products.

Name fatty-acid–CoA ligase (hexadecanoate)

Reaction equation M atp c + M coa c + M hdca c )−−−−* M amp c + M pmtcoa c + M ppi c (693)

Reactants

348 Produced by SBML2LATEX Table 611: Properties of each reactant. Id Name SBO M atp c ATP M coa c Coenzyme A M hdca c Hexadecanoate (n-C16:0)

Products

Table 612: Properties of each product. Id Name SBO M amp c AMP M pmtcoa c Palmitoyl-CoA (n-C16:0CoA) M ppi c Diphosphate

Kinetic Law

v347 = not speciﬁed (694)

6.348 Reaction R FACOAL161 This is a reversible reaction of three reactants forming three products.

Name fatty-acid–CoA ligase (hexadecenoate)

Reaction equation M atp c + M coa c + M hdcea c )−−−−* M amp c + M hdcoa c + M ppi c (695)

Reactants

Table 613: Properties of each reactant. Id Name SBO M atp c ATP M coa c Coenzyme A M hdcea c Hexadecenoate (n-C16:1)

Products

Produced by SBML2LATEX 349 Table 614: Properties of each product. Id Name SBO M amp c AMP M hdcoa c Hexadecenoyl-CoA (n-C16:1CoA) M ppi c Diphosphate

Kinetic Law

v348 = not speciﬁed (696)

6.349 Reaction R FACOAL180 This is a reversible reaction of three reactants forming three products.

Name fatty-acid–CoA ligase (octadecanoate)

Reaction equation M atp c + M coa c + M ocdca c )−−−−* M amp c + M ppi c + M stcoa c (697)

Reactants

Table 615: Properties of each reactant. Id Name SBO M atp c ATP M coa c Coenzyme A M ocdca c octadecanoate (n-C18:0)

Products

Table 616: Properties of each product. Id Name SBO M amp c AMP M ppi c Diphosphate M stcoa c Stearoyl-CoA (n-C18:0CoA)

Kinetic Law

v349 = not speciﬁed (698)

350 Produced by SBML2LATEX 6.350 Reaction R FACOAL181 This is a reversible reaction of three reactants forming three products.

Name fatty-acid–CoA ligase (octadecenoate)

Reaction equation M atp c + M coa c + M ocdcea c )−−−−* M amp c + M odecoa c + M ppi c (699)

Reactants

Table 617: Properties of each reactant. Id Name SBO M atp c ATP M coa c Coenzyme A M ocdcea c octadecenoate (n-C18:1)

Products

Table 618: Properties of each product. Id Name SBO M amp c AMP M odecoa c Octadecenoyl-CoA (n-C18:1CoA) M ppi c Diphosphate

Kinetic Law

v350 = not speciﬁed (700)

6.351 Reaction R FACOAL200 This is a reversible reaction of three reactants forming three products.

Name fatty-acid–CoA ligase

Reaction equation M arach c + M atp c + M coa c )−−−−* M amp c + M arachcoa c + M ppi c (701)

Reactants

Produced by SBML2LATEX 351 Table 619: Properties of each reactant. Id Name SBO M arach c Arachidic acid M atp c ATP M coa c Coenzyme A

Products

Table 620: Properties of each product. Id Name SBO M amp c AMP M arachcoa c arachidyl coenzyme A M ppi c Diphosphate

Kinetic Law

v351 = not speciﬁed (702)

6.352 Reaction R FACOAL80 This is a reversible reaction of three reactants forming three products.

Name fatty-acid–CoA ligase (octanoate)

Reaction equation M atp c + M coa c + M octa c )−−−−* M amp c + M occoa c + M ppi c (703)

Reactants

Table 621: Properties of each reactant. Id Name SBO M atp c ATP M coa c Coenzyme A M octa c octanoate (n-C8:0)

Products

352 Produced by SBML2LATEX Table 622: Properties of each product. Id Name SBO M amp c AMP M occoa c Octanoyl-CoA (n-C8:0CoA) M ppi c Diphosphate

Kinetic Law

v352 = not speciﬁed (704)

6.353 Reaction R FACOALPHDCA This is a reversible reaction of three reactants forming three products.

Name fatty-acid–CoA ligase

Reaction equation M atp c + M coa c + M phdca c )−−−−* M amp c + M phdcacoa c + M ppi c (705)

Reactants

Table 623: Properties of each reactant. Id Name SBO M atp c ATP M coa c Coenzyme A M phdca c phenol palmitic acid

Products

Table 624: Properties of each product. Id Name SBO M amp c AMP M phdcacoa c phenol palmitic coenzyme A M ppi c Diphosphate

Kinetic Law

v353 = not speciﬁed (706)

Produced by SBML2LATEX 353 6.354 Reaction R FACOALPREPH This is a reversible reaction of three reactants forming three products.

Name fatty-acid–CoA ligase (phthiocerol precursor)

Reaction equation M atp c + M coa c + M prephth c )−−−−* M amp c + M ppi c + M prephthcoa c (707)

Reactants

Table 625: Properties of each reactant. Id Name SBO M atp c ATP M coa c Coenzyme A M prephth c phthiocerol precursor

Products

Table 626: Properties of each product. Id Name SBO M amp c AMP M ppi c Diphosphate M prephthcoa c phthiocerol precursor bound coenzyme A

Kinetic Law

v354 = not speciﬁed (708)

6.355 Reaction R FAH4 This is an irreversible reaction of four reactants forming three products.

Name Fatty acid hydroxylase

Reaction equation M h c + M nadph c + M o2 c + M omtta c −→ M h2o c + M homtta c + M nadp c (709)

Reactants

354 Produced by SBML2LATEX Table 627: Properties of each reactant. Id Name SBO M h c H+ M nadph c Nicotinamide adenine dinucleotide phosphate - reduced M o2 c O2 M omtta c octa-methyl tetracontatricosanoic acid (C34:0, 8 methyl-branched carbons)

Products

Table 628: Properties of each product. Id Name SBO M h2o c H2O M homtta c 10 hydroxy octa-methyl tetracontatricosanoic acid (C34:0, 8 methyl-branched carbons, 1 hydroxylated carbon) M nadp c Nicotinamide adenine dinucleotide phosphate

Kinetic Law

v355 = not speciﬁed (710)

6.356 Reaction R FAMPL1 This is an irreversible reaction of three reactants forming two products.

Name Fatty Acid Ligase AMP (mycolic acid)

Reaction equation M amp c + M h c + M meroacidcyc2ACP c −→ M ACP c + M meroacidcyc2AMP c (711)

Reactants

Table 629: Properties of each reactant. Id Name SBO M amp c AMP M h c H+ M meroacidcyc2ACP c cyclopropanated alpha meroacid ACP (2 cyclopropane rings)

Products

Produced by SBML2LATEX 355 Table 630: Properties of each product. Id Name SBO M ACP c acyl carrier protein M meroacidcyc2AMP c cyclopropanated alpha meroacid AMP (2 cyclopropane rings)

Kinetic Law

v356 = not speciﬁed (712)

6.357 Reaction R FAMPL2 This is an irreversible reaction of three reactants forming two products.

Name Fatty Acid Ligase AMP (mycolic acid)

Reaction equation M amp c + M h c + M mmeroacidcyc2ACP c −→ M ACP c + M mmeroacidcyc2AMP c (713)

Reactants

Table 631: Properties of each reactant. Id Name SBO M amp c AMP M h c H+ M mmeroacidcyc2ACP c cyclopropanated methoxy-meroacid ACP (2 cyclopropane rings)

Products

Table 632: Properties of each product. Id Name SBO M ACP c acyl carrier protein M mmeroacidcyc2AMP c cyclopropanated methoxy-meroacid AMP (2 cyclopropane rings)

Kinetic Law

v357 = not speciﬁed (714)

356 Produced by SBML2LATEX 6.358 Reaction R FAMPL3 This is an irreversible reaction of three reactants forming two products.

Name Fatty Acid Ligase AMP (mycolic acid)

Reaction equation M amp c + M h c + M kmeroacidcyc2ACP c −→ M ACP c + M kmeroacidcyc2AMP c (715)

Reactants

Table 633: Properties of each reactant. Id Name SBO M amp c AMP M h c H+ M kmeroacidcyc2ACP c cyclopropanated keto-meroacid ACP (2 cyclopropane rings)

Products

Table 634: Properties of each product. Id Name SBO M ACP c acyl carrier protein M kmeroacidcyc2AMP c cyclopropanated keto-meroacid AMP (2 cyclopropane rings)

Kinetic Law

v358 = not speciﬁed (716)

6.359 Reaction R FAMPL4 This is an irreversible reaction of three reactants forming two products.

Name Fatty Acid Ligase AMP (mycolic acid)

Reaction equation

M amp c + M h c + M mmmeroacidcyc1ACP c −→ M ACP c + M mmmeroacidcyc1AMP c (717)

Produced by SBML2LATEX 357 Reactants

358 Produced by SBML2LATEX Table 635: Properties of each reactant. Id Name SBO M amp c AMP M h c H+ M mmmeroacidcyc1ACP c cyclopropanated methyl hydroxy methoxy meroacid ACP (1 cyclopropane ring)

Products

Table 636: Properties of each product. Id Name SBO M ACP c acyl carrier protein M mmmeroacidcyc1AMP c cyclopropanated methyl hydroxy methoxy meroacid AMP (1 cyclopropane ring)

Kinetic Law

v359 = not speciﬁed (718)

6.360 Reaction R FAMPL5 This is an irreversible reaction of three reactants forming two products.

Name Fatty Acid Ligase AMP (mycolic acid)

Reaction equation M amp c + M h c + M mkmeroacidcyc1ACP c −→ M ACP c + M mkmeroacidcyc1AMP c (719)

Reactants

Table 637: Properties of each reactant. Id Name SBO M amp c AMP M h c H+ M mkmeroacidcyc1ACP c cyclopropanated methyl hydroxy keto meroacid ACP (1 cyclopropane ring)

Products

Produced by SBML2LATEX 359 Table 638: Properties of each product. Id Name SBO M ACP c acyl carrier protein M mkmeroacidcyc1AMP c cyclopropanated methyl hydroxy keto meroacid AMP (1 cyclopropane ring)

Kinetic Law

v360 = not speciﬁed (720)

6.361 Reaction R FAO1 This is an irreversible reaction of six reactants forming six products.

Name Fatty acid oxidation (tetradecanoate)

Reaction equation M atp c + 7M coa c + 6M fad c + 6M h2o c + 6M nad c + M ttdca c −→ 7M accoa c + M amp c + 6M fadh2 c + 6M h c + 6M nadh c + M ppi c (721)

Reactants

Table 639: Properties of each reactant. Id Name SBO M atp c ATP M coa c Coenzyme A M fad c Flavin adenine dinucleotide oxidized M h2o c H2O M nad c Nicotinamide adenine dinucleotide M ttdca c tetradecanoate (n-C14:0)

Products

Table 640: Properties of each product. Id Name SBO M accoa c Acetyl-CoA M amp c AMP M fadh2 c Flavin adenine dinucleotide reduced M h c H+

360 Produced by SBML2LATEX Id Name SBO M nadh c Nicotinamide adenine dinucleotide - reduced M ppi c Diphosphate

Kinetic Law

v361 = not speciﬁed (722)

6.362 Reaction R FAO10 This is an irreversible reaction of six reactants forming six products.

Name Fatty acid oxidation (octadecenoate)

Reaction equation M atp c + 9M coa c + 7M fad c + 8M h2o c + 8M nad c + M ocdcea c −→ 9M accoa c + M amp c + 7M fadh2 c + 8M h c + 8M nadh c + M ppi c (723)

Reactants

Table 641: Properties of each reactant. Id Name SBO M atp c ATP M coa c Coenzyme A M fad c Flavin adenine dinucleotide oxidized M h2o c H2O M nad c Nicotinamide adenine dinucleotide M ocdcea c octadecenoate (n-C18:1)

Products

Table 642: Properties of each product. Id Name SBO M accoa c Acetyl-CoA M amp c AMP M fadh2 c Flavin adenine dinucleotide reduced M h c H+ M nadh c Nicotinamide adenine dinucleotide - reduced M ppi c Diphosphate

Produced by SBML2LATEX 361 Kinetic Law

v362 = not speciﬁed (724)

6.363 Reaction R FAO11 This is an irreversible reaction of six reactants forming six products.

Name Fatty acid oxidation (n-C16:1)

Reaction equation M atp c + 8M coa c + 6M fad c + 7M h2o c + M hdcea c + 7M nad c −→ 8M accoa c + M amp c + 6M fadh2 c + 7M h c + 7M nadh c + M ppi c (725)

Reactants

Table 643: Properties of each reactant. Id Name SBO M atp c ATP M coa c Coenzyme A M fad c Flavin adenine dinucleotide oxidized M h2o c H2O M hdcea c Hexadecenoate (n-C16:1) M nad c Nicotinamide adenine dinucleotide

Products

Table 644: Properties of each product. Id Name SBO M accoa c Acetyl-CoA M amp c AMP M fadh2 c Flavin adenine dinucleotide reduced M h c H+ M nadh c Nicotinamide adenine dinucleotide - reduced M ppi c Diphosphate

Kinetic Law

v363 = not speciﬁed (726)

362 Produced by SBML2LATEX 6.364 Reaction R FAO2 This is an irreversible reaction of six reactants forming six products.

Name Fatty acid oxidation (n-C16:0)

Reaction equation M atp c + 8M coa c + 7M fad c + 7M h2o c + M hdca c + 7M nad c −→ 8M accoa c + M amp c + 7M fadh2 c + 7M h c + 7M nadh c + M ppi c (727)

Reactants

Table 645: Properties of each reactant. Id Name SBO M atp c ATP M coa c Coenzyme A M fad c Flavin adenine dinucleotide oxidized M h2o c H2O M hdca c Hexadecanoate (n-C16:0) M nad c Nicotinamide adenine dinucleotide

Products

Table 646: Properties of each product. Id Name SBO M accoa c Acetyl-CoA M amp c AMP M fadh2 c Flavin adenine dinucleotide reduced M h c H+ M nadh c Nicotinamide adenine dinucleotide - reduced M ppi c Diphosphate

Kinetic Law

v364 = not speciﬁed (728)

6.365 Reaction R FAO3 This is an irreversible reaction of six reactants forming six products. Name Fatty acid oxidation (octadecanoate)

Produced by SBML2LATEX 363 Reaction equation M atp c + 9M coa c + 8M fad c + 8M h2o c + 8M nad c + M ocdca c −→ 9M accoa c + M amp c + 8M fadh2 c + 8M h c + 8M nadh c + M ppi c (729)

Reactants

Table 647: Properties of each reactant. Id Name SBO M atp c ATP M coa c Coenzyme A M fad c Flavin adenine dinucleotide oxidized M h2o c H2O M nad c Nicotinamide adenine dinucleotide M ocdca c octadecanoate (n-C18:0)

Products

Table 648: Properties of each product. Id Name SBO M accoa c Acetyl-CoA M amp c AMP M fadh2 c Flavin adenine dinucleotide reduced M h c H+ M nadh c Nicotinamide adenine dinucleotide - reduced M ppi c Diphosphate

Kinetic Law

v365 = not speciﬁed (730)

6.366 Reaction R FAS100 This is an irreversible reaction of four reactants forming ﬁve products.

Name fatty acid synthase (n-C10:0)

Reaction equation 3M h c + M malcoa c + 2M nadph c + M octa c −→ M co2 c + M coa c + M dca c + M h2o c + 2M nadp c (731)

364 Produced by SBML2LATEX Reactants

Table 649: Properties of each reactant. Id Name SBO M h c H+ M malcoa c Malonyl-CoA M nadph c Nicotinamide adenine dinucleotide phosphate - reduced M octa c octanoate (n-C8:0)

Products

Table 650: Properties of each product. Id Name SBO M co2 c CO2 M coa c Coenzyme A M dca c Decanoate (n-C10:0) M h2o c H2O M nadp c Nicotinamide adenine dinucleotide phosphate

Kinetic Law

v366 = not speciﬁed (732)

6.367 Reaction R FAS120 This is an irreversible reaction of four reactants forming ﬁve products.

Name fatty acid synthase (n-C12:0)

Reaction equation M dca c + 3M h c + M malcoa c + 2M nadph c −→ M co2 c + M coa c + M ddca c + M h2o c + 2M nadp c (733)

Reactants

Table 651: Properties of each reactant. Id Name SBO M dca c Decanoate (n-C10:0)

Produced by SBML2LATEX 365 Id Name SBO M h c H+ M malcoa c Malonyl-CoA M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

Products

Table 652: Properties of each product. Id Name SBO M co2 c CO2 M coa c Coenzyme A M ddca c Dodecanoate (n-C12:0) M h2o c H2O M nadp c Nicotinamide adenine dinucleotide phosphate

Kinetic Law

v367 = not speciﬁed (734)

6.368 Reaction R FAS140 This is an irreversible reaction of four reactants forming ﬁve products.

Name fatty acid synthase (n-C14:0)

Reaction equation M ddca c + 3M h c + M malcoa c + 2M nadph c −→ M co2 c + M coa c + M h2o c + 2M nadp c + M ttdca c (735)

Reactants

Table 653: Properties of each reactant. Id Name SBO M ddca c Dodecanoate (n-C12:0) M h c H+ M malcoa c Malonyl-CoA M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

366 Produced by SBML2LATEX Products

Table 654: Properties of each product. Id Name SBO M co2 c CO2 M coa c Coenzyme A M h2o c H2O M nadp c Nicotinamide adenine dinucleotide phosphate M ttdca c tetradecanoate (n-C14:0)

Kinetic Law

v368 = not speciﬁed (736)

6.369 Reaction R FAS160 This is an irreversible reaction of four reactants forming ﬁve products.

Name fatty acid synthase (n-C16:0)

Reaction equation 3M h c + M malcoa c + 2M nadph c + M ttdca c −→ M co2 c + M coa c + M h2o c + M hdca c + 2M nadp c (737)

Reactants

Table 655: Properties of each reactant. Id Name SBO M h c H+ M malcoa c Malonyl-CoA M nadph c Nicotinamide adenine dinucleotide phosphate - reduced M ttdca c tetradecanoate (n-C14:0)

Products

Table 656: Properties of each product. Id Name SBO M co2 c CO2

Produced by SBML2LATEX 367 Id Name SBO M coa c Coenzyme A M h2o c H2O M hdca c Hexadecanoate (n-C16:0) M nadp c Nicotinamide adenine dinucleotide phosphate

Kinetic Law

v369 = not speciﬁed (738)

6.370 Reaction R FAS161 This is an irreversible reaction of ﬁve reactants forming ﬁve products.

Name fatty acid synthase (n-C16:1)

Reaction equation 4M h c + M malcoa c + 3M nadph c + M o2 c + M ttdca c −→ M co2 c + M coa c + 3M h2o c + M hdcea c + 3M nadp c (739)

Reactants

Table 657: Properties of each reactant. Id Name SBO M h c H+ M malcoa c Malonyl-CoA M nadph c Nicotinamide adenine dinucleotide phosphate - reduced M o2 c O2 M ttdca c tetradecanoate (n-C14:0)

Products

Table 658: Properties of each product. Id Name SBO M co2 c CO2 M coa c Coenzyme A M h2o c H2O M hdcea c Hexadecenoate (n-C16:1) M nadp c Nicotinamide adenine dinucleotide phosphate

368 Produced by SBML2LATEX Kinetic Law

v370 = not speciﬁed (740)

6.371 Reaction R FAS180 This is an irreversible reaction of four reactants forming ﬁve products.

Name fatty acid synthase (n-C18:0)

Reaction equation 3M h c + M hdca c + M malcoa c + 2M nadph c −→ M co2 c + M coa c + M h2o c + 2M nadp c + M ocdca c (741)

Reactants

Table 659: Properties of each reactant. Id Name SBO M h c H+ M hdca c Hexadecanoate (n-C16:0) M malcoa c Malonyl-CoA M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

Products

Table 660: Properties of each product. Id Name SBO M co2 c CO2 M coa c Coenzyme A M h2o c H2O M nadp c Nicotinamide adenine dinucleotide phosphate M ocdca c octadecanoate (n-C18:0)

Kinetic Law

v371 = not speciﬁed (742)

6.372 Reaction R FAS181 This is an irreversible reaction of ﬁve reactants forming ﬁve products.

Produced by SBML2LATEX 369 Name fatty acid synthase (n-C18:1)

Reaction equation 4M h c + M hdca c + M malcoa c + 3M nadph c + M o2 c −→ M co2 c + M coa c + 3M h2o c + 3M nadp c + M ocdcea c (743)

Reactants

Table 661: Properties of each reactant. Id Name SBO M h c H+ M hdca c Hexadecanoate (n-C16:0) M malcoa c Malonyl-CoA M nadph c Nicotinamide adenine dinucleotide phosphate - reduced M o2 c O2

Products

Table 662: Properties of each product. Id Name SBO M co2 c CO2 M coa c Coenzyme A M h2o c H2O M nadp c Nicotinamide adenine dinucleotide phosphate M ocdcea c octadecenoate (n-C18:1)

Kinetic Law

v372 = not speciﬁed (744)

6.373 Reaction R FAS200 This is an irreversible reaction of four reactants forming ﬁve products.

Name fatty acid synthase (n-C20:0)

Reaction equation 3M h c + M malcoa c + 2M nadph c + M ocdca c −→ M arach c + M co2 c + M coa c + M h2o c + 2M nadp c (745)

370 Produced by SBML2LATEX Reactants

Table 663: Properties of each reactant. Id Name SBO M h c H+ M malcoa c Malonyl-CoA M nadph c Nicotinamide adenine dinucleotide phosphate - reduced M ocdca c octadecanoate (n-C18:0)

Products

Table 664: Properties of each product. Id Name SBO M arach c Arachidic acid M co2 c CO2 M coa c Coenzyme A M h2o c H2O M nadp c Nicotinamide adenine dinucleotide phosphate

Kinetic Law

v373 = not speciﬁed (746)

6.374 Reaction R FAS240 L This is an irreversible reaction of four reactants forming ﬁve products.

Name fatty acid synthase (n-C24:0), lumped reaction

Reaction equation 9M h c + 3M malcoa c + 6M nadph c + M ocdca c −→ 3M co2 c + 3M coa c + 3M h2o c + 6M nadp c + M ttc c (747)

Reactants

Table 665: Properties of each reactant. Id Name SBO M h c H+

Produced by SBML2LATEX 371 Id Name SBO M malcoa c Malonyl-CoA M nadph c Nicotinamide adenine dinucleotide phosphate - reduced M ocdca c octadecanoate (n-C18:0)

Products

Table 666: Properties of each product. Id Name SBO M co2 c CO2 M coa c Coenzyme A M h2o c H2O M nadp c Nicotinamide adenine dinucleotide phosphate M ttc c tetracosanoate (n-C24:0)

Kinetic Law

v374 = not speciﬁed (748)

6.375 Reaction R FAS260 This is an irreversible reaction of four reactants forming ﬁve products.

Name fatty acid synthase (n-C26:0)

Reaction equation 3M h c + M malcoa c + 2M nadph c + M ttc c −→ M co2 c + M coa c + M h2o c + M hexc c + 2M nadp c (749)

Reactants

Table 667: Properties of each reactant. Id Name SBO M h c H+ M malcoa c Malonyl-CoA M nadph c Nicotinamide adenine dinucleotide phosphate - reduced M ttc c tetracosanoate (n-C24:0)

372 Produced by SBML2LATEX Products

Table 668: Properties of each product. Id Name SBO M co2 c CO2 M coa c Coenzyme A M h2o c H2O M hexc c hexacosanoate (n-C26:0) M nadp c Nicotinamide adenine dinucleotide phosphate

Kinetic Law

v375 = not speciﬁed (750)

6.376 Reaction R FAS80 L This is an irreversible reaction of four reactants forming ﬁve products.

Name fatty acid synthase (n-C8:0), lumped reaction

Reaction equation M accoa c + 8M h c + 3M malcoa c + 6M nadph c −→ 3M co2 c + 4M coa c + 2M h2o c + 6M nadp c + M octa c (751)

Reactants

Table 669: Properties of each reactant. Id Name SBO M accoa c Acetyl-CoA M h c H+ M malcoa c Malonyl-CoA M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

Products

Table 670: Properties of each product. Id Name SBO M co2 c CO2

Produced by SBML2LATEX 373 Id Name SBO M coa c Coenzyme A M h2o c H2O M nadp c Nicotinamide adenine dinucleotide phosphate M octa c octanoate (n-C8:0)

Kinetic Law

v376 = not speciﬁed (752)

6.377 Reaction R FASPHDCA This is an irreversible reaction of four reactants forming ﬁve products.

Name fatty-acyl-ACP synthase (phdca)

Reaction equation M 4hbzACP c + 24M h c + 8M malACP c + 16M nadph c −→ 8M ACP c + 8M co2 c + 8M h2o c + 16M nadp c + M phdcaACP c (753)

Reactants

Table 671: Properties of each reactant. Id Name SBO M 4hbzACP c 4-hydroxybenzoyl ACP M h c H+ M malACP c Malonyl-[acyl-carrier protein] M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

Products

Table 672: Properties of each product. Id Name SBO M ACP c acyl carrier protein M co2 c CO2 M h2o c H2O M nadp c Nicotinamide adenine dinucleotide phosphate M phdcaACP c phenol palmitic acid ACP

374 Produced by SBML2LATEX Kinetic Law

v377 = not speciﬁed (754)

6.378 Reaction R FASm1601 This is an irreversible reaction of four reactants forming ﬁve products.

Name fatty acid synthase - methyl octadecanoic acid

Reaction equation 3M h c + M hdca c + M mmcoa DASH S c + 2M nadph c −→ M co2 c + M coa c + M h2o c + M m1ocdca c + 2M nadp c (755)

Reactants

Table 673: Properties of each reactant. Id Name SBO M h c H+ M hdca c Hexadecanoate (n-C16:0) M mmcoa DASH S c (S)-Methylmalonyl-CoA M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

Products

Table 674: Properties of each product. Id Name SBO M co2 c CO2 M coa c Coenzyme A M h2o c H2O M m1ocdca c methyl octadecanoate M nadp c Nicotinamide adenine dinucleotide phosphate

Kinetic Law

v378 = not speciﬁed (756)

6.379 Reaction R FASm180 This is an irreversible reaction of ﬁve reactants forming ﬁve products.

Produced by SBML2LATEX 375 Name fatty acid synthase - tuberculostearic acid

Reaction equation 15M h c + 4M malcoa c + M mmcoa DASH S c + 10M nadph c + M octa c −→ 5M co2 c + 5M coa c + 5M h2o c + M mocdca c + 10M nadp c (757)

Reactants

Table 675: Properties of each reactant. Id Name SBO M h c H+ M malcoa c Malonyl-CoA M mmcoa DASH S c (S)-Methylmalonyl-CoA M nadph c Nicotinamide adenine dinucleotide phosphate - reduced M octa c octanoate (n-C8:0)

Products

Table 676: Properties of each product. Id Name SBO M co2 c CO2 M coa c Coenzyme A M h2o c H2O M mocdca c 10-methylstearic acid M nadp c Nicotinamide adenine dinucleotide phosphate

Kinetic Law

v379 = not speciﬁed (758)

6.380 Reaction R FASm1801 This is an irreversible reaction of four reactants forming ﬁve products.

Name fatty acid synthase - dimethyl arachic acid

Reaction equation 3M h c + M m1ocdca c + M mmcoa DASH S c + 2M nadph c −→ M co2 c + M coa c + M dmarach c + M h2o c + 2M nadp c (759)

376 Produced by SBML2LATEX Reactants

Table 677: Properties of each reactant. Id Name SBO M h c H+ M m1ocdca c methyl octadecanoate M mmcoa DASH S c (S)-Methylmalonyl-CoA M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

Products

Table 678: Properties of each product. Id Name SBO M co2 c CO2 M coa c Coenzyme A M dmarach c di-methyl arachic acid M h2o c H2O M nadp c Nicotinamide adenine dinucleotide phosphate

Kinetic Law

v380 = not speciﬁed (760)

6.381 Reaction R FASm2001 This is an irreversible reaction of four reactants forming ﬁve products.

Name fatty acid synthase - tri-methyl behenic acid

Reaction equation M dmarach c + 3M h c + M mmcoa DASH S c + 2M nadph c −→ M co2 c + M coa c + M h2o c + 2M nadp c + M tmbhn c (761)

Reactants

Table 679: Properties of each reactant. Id Name SBO M dmarach c di-methyl arachic acid

Produced by SBML2LATEX 377 Id Name SBO M h c H+ M mmcoa DASH S c (S)-Methylmalonyl-CoA M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

Products

Table 680: Properties of each product. Id Name SBO M co2 c CO2 M coa c Coenzyme A M h2o c H2O M nadp c Nicotinamide adenine dinucleotide phosphate M tmbhn c tri-methyl behenic acid

Kinetic Law

v381 = not speciﬁed (762)

6.382 Reaction R FASm2002 This is an irreversible reaction of four reactants forming ﬁve products.

Name fatty acid synthase - methyl-arachidic acid

Reaction equation 3M h c + M mmcoa DASH S c + 2M nadph c + M ocdca c −→ M co2 c + M coa c + M h2o c + M marach c + 2M nadp c (763)

Reactants

Table 681: Properties of each reactant. Id Name SBO M h c H+ M mmcoa DASH S c (S)-Methylmalonyl-CoA M nadph c Nicotinamide adenine dinucleotide phosphate - reduced M ocdca c octadecanoate (n-C18:0)

378 Produced by SBML2LATEX Products

Table 682: Properties of each product. Id Name SBO M co2 c CO2 M coa c Coenzyme A M h2o c H2O M marach c methyl arachidic acid M nadp c Nicotinamide adenine dinucleotide phosphate

Kinetic Law

v382 = not speciﬁed (764)

6.383 Reaction R FASm220 This is an irreversible reaction of four reactants forming ﬁve products.

Name fatty acid synthase - methyl-behenic acid

Reaction equation M arach c + 3M h c + M mmcoa DASH S c + 2M nadph c −→ M co2 c + M coa c + M h2o c + M mbhn c + 2M nadp c (765)

Reactants

Table 683: Properties of each reactant. Id Name SBO M arach c Arachidic acid M h c H+ M mmcoa DASH S c (S)-Methylmalonyl-CoA M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

Products

Table 684: Properties of each product. Id Name SBO M co2 c CO2

Produced by SBML2LATEX 379 Id Name SBO M coa c Coenzyme A M h2o c H2O M mbhn c methyl behenic acid M nadp c Nicotinamide adenine dinucleotide phosphate

Kinetic Law

v383 = not speciﬁed (766)

6.384 Reaction R FASm2201 This is an irreversible reaction of four reactants forming ﬁve products.

Name fatty acid synthase - tri-methyl lignoceric acid

Reaction equation 3M h c + M mmcoa DASH S c + 2M nadph c + M tmbhn c −→ M co2 c + M coa c + M h2o c + 2M nadp c + M tamlgnc c (767)

Reactants

Table 685: Properties of each reactant. Id Name SBO M h c H+ M mmcoa DASH S c (S)-Methylmalonyl-CoA M nadph c Nicotinamide adenine dinucleotide phosphate - reduced M tmbhn c tri-methyl behenic acid

Products

Table 686: Properties of each product. Id Name SBO M co2 c CO2 M coa c Coenzyme A M h2o c H2O M nadp c Nicotinamide adenine dinucleotide phosphate M tamlgnc c tri-methyl lignoceric acid

380 Produced by SBML2LATEX Kinetic Law

v384 = not speciﬁed (768)

6.385 Reaction R FASm2202 This is an irreversible reaction of four reactants forming ﬁve products.

Name fatty acid synthase - di-methyl-behenic acid

Reaction equation 3M h c + M marach c + M mmcoa DASH S c + 2M nadph c −→ M co2 c + M coa c + M dmbhn c + M h2o c + 2M nadp c (769)

Reactants

Table 687: Properties of each reactant. Id Name SBO M h c H+ M marach c methyl arachidic acid M mmcoa DASH S c (S)-Methylmalonyl-CoA M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

Products

Table 688: Properties of each product. Id Name SBO M co2 c CO2 M coa c Coenzyme A M dmbhn c di-methyl behenic acid M h2o c H2O M nadp c Nicotinamide adenine dinucleotide phosphate

Kinetic Law

v385 = not speciﬁed (770)

6.386 Reaction R FASm240 This is an irreversible reaction of four reactants forming ﬁve products.

Produced by SBML2LATEX 381 Name fatty acid synthase - di-methyl lignoceric acid

Reaction equation 3M h c + M mbhn c + M mmcoa DASH S c + 2M nadph c −→ M co2 c + M coa c + M dmlgnc c + M h2o c + 2M nadp c (771)

Reactants

Table 689: Properties of each reactant. Id Name SBO M h c H+ M mbhn c methyl behenic acid M mmcoa DASH S c (S)-Methylmalonyl-CoA M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

Products

Table 690: Properties of each product. Id Name SBO M co2 c CO2 M coa c Coenzyme A M dmlgnc c dimethyl lignoceric acid M h2o c H2O M nadp c Nicotinamide adenine dinucleotide phosphate

Kinetic Law

v386 = not speciﬁed (772)

6.387 Reaction R FASm2401 This is an irreversible reaction of four reactants forming ﬁve products.

Name fatty acid synthase - penta-methyl hexacosanoic acid

Reaction equation

3M h c + M mmcoa DASH S c + 2M nadph c + M tamlgnc c −→ M co2 c + M coa c + M h2o c + 2M nadp c + M pmhexc c (773)

382 Produced by SBML2LATEX Reactants

Table 691: Properties of each reactant. Id Name SBO M h c H+ M mmcoa DASH S c (S)-Methylmalonyl-CoA M nadph c Nicotinamide adenine dinucleotide phosphate - reduced M tamlgnc c tri-methyl lignoceric acid

Products

Table 692: Properties of each product. Id Name SBO M co2 c CO2 M coa c Coenzyme A M h2o c H2O M nadp c Nicotinamide adenine dinucleotide phosphate M pmhexc c penta-methyl hexacosanoate

Kinetic Law

v387 = not speciﬁed (774)

6.388 Reaction R FASm2402 This is an irreversible reaction of four reactants forming ﬁve products.

Name fatty acid synthase - tri-methyl-lignoceric acid

Reaction equation M dmbhn c + 3M h c + M mmcoa DASH S c + 2M nadph c −→ M co2 c + M coa c + M h2o c + 2M nadp c + M tmlgnc c (775)

Reactants

Table 693: Properties of each reactant. Id Name SBO M dmbhn c di-methyl behenic acid

Produced by SBML2LATEX 383 Id Name SBO M h c H+ M mmcoa DASH S c (S)-Methylmalonyl-CoA M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

Products

Table 694: Properties of each product. Id Name SBO M co2 c CO2 M coa c Coenzyme A M h2o c H2O M nadp c Nicotinamide adenine dinucleotide phosphate M tmlgnc c tri-methyl lignoceric acid

Kinetic Law

v388 = not speciﬁed (776)

6.389 Reaction R FASm260 This is an irreversible reaction of four reactants forming ﬁve products.

Name fatty acid synthase - tri-methyl cerotic acid

Reaction equation M dmlgnc c + 3M h c + M mmcoa DASH S c + 2M nadph c −→ M co2 c + M coa c + M h2o c + 2M nadp c + M tmhexc c (777)

Reactants

Table 695: Properties of each reactant. Id Name SBO M dmlgnc c dimethyl lignoceric acid M h c H+ M mmcoa DASH S c (S)-Methylmalonyl-CoA M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

384 Produced by SBML2LATEX Products

Table 696: Properties of each product. Id Name SBO M co2 c CO2 M coa c Coenzyme A M h2o c H2O M nadp c Nicotinamide adenine dinucleotide phosphate M tmhexc c tri-methyl hexacosanoate

Kinetic Law

v389 = not speciﬁed (778)

6.390 Reaction R FASm2601 This is an irreversible reaction of four reactants forming ﬁve products.

Name fatty acid synthase - hexa-methyl octacosanoic acid

Reaction equation 3M h c + M mmcoa DASH S c + 2M nadph c + M pmhexc c −→ M co2 c + M coa c + M h2o c + M hmocta c + 2M nadp c (779)

Reactants

Table 697: Properties of each reactant. Id Name SBO M h c H+ M mmcoa DASH S c (S)-Methylmalonyl-CoA M nadph c Nicotinamide adenine dinucleotide phosphate - reduced M pmhexc c penta-methyl hexacosanoate

Products

Table 698: Properties of each product. Id Name SBO M co2 c CO2

Produced by SBML2LATEX 385 Id Name SBO M coa c Coenzyme A M h2o c H2O M hmocta c hexa-methyl octacosanoate M nadp c Nicotinamide adenine dinucleotide phosphate

Kinetic Law

v390 = not speciﬁed (780)

6.391 Reaction R FASm2602 This is an irreversible reaction of four reactants forming ﬁve products.

Name fatty acid synthase - tetra-methyl hexacosanoic acid

Reaction equation 3M h c + M mmcoa DASH S c + 2M nadph c + M tmlgnc c −→ M co2 c + M coa c + M h2o c + 2M nadp c + M tamhexc c (781)

Reactants

Table 699: Properties of each reactant. Id Name SBO M h c H+ M mmcoa DASH S c (S)-Methylmalonyl-CoA M nadph c Nicotinamide adenine dinucleotide phosphate - reduced M tmlgnc c tri-methyl lignoceric acid

Products

Table 700: Properties of each product. Id Name SBO M co2 c CO2 M coa c Coenzyme A M h2o c H2O M nadp c Nicotinamide adenine dinucleotide phosphate M tamhexc c tetra-methyl hexacosanoate

386 Produced by SBML2LATEX Kinetic Law

v391 = not speciﬁed (782)

6.392 Reaction R FASm280 This is an irreversible reaction of four reactants forming ﬁve products.

Name fatty acid synthase - tetra-methyl octacosanoic acid

Reaction equation 3M h c + M mmcoa DASH S c + 2M nadph c + M tmhexc c −→ M co2 c + M coa c + M h2o c + 2M nadp c + M tamocta c (783)

Reactants

Table 701: Properties of each reactant. Id Name SBO M h c H+ M mmcoa DASH S c (S)-Methylmalonyl-CoA M nadph c Nicotinamide adenine dinucleotide phosphate - reduced M tmhexc c tri-methyl hexacosanoate

Products

Table 702: Properties of each product. Id Name SBO M co2 c CO2 M coa c Coenzyme A M h2o c H2O M nadp c Nicotinamide adenine dinucleotide phosphate M tamocta c tetra-methyl octacosanoate

Kinetic Law

v392 = not speciﬁed (784)

6.393 Reaction R FASm2801 This is an irreversible reaction of four reactants forming ﬁve products.

Produced by SBML2LATEX 387 Name fatty acid synthase - hepta-methyl triacontanoic acid

Reaction equation 3M h c + M hmocta c + M mmcoa DASH S c + 2M nadph c −→ M co2 c + M coa c + M h2o c + M hpmtria c + 2M nadp c (785)

Reactants

Table 703: Properties of each reactant. Id Name SBO M h c H+ M hmocta c hexa-methyl octacosanoate M mmcoa DASH S c (S)-Methylmalonyl-CoA M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

Products

Table 704: Properties of each product. Id Name SBO M co2 c CO2 M coa c Coenzyme A M h2o c H2O M hpmtria c hepta-methyl triacontanoic acid (C30:0, plus 7 methyl branches) M nadp c Nicotinamide adenine dinucleotide phosphate

Kinetic Law

v393 = not speciﬁed (786)

6.394 Reaction R FASm2802 This is an irreversible reaction of four reactants forming ﬁve products.

Name fatty acid synthase - penta-methyl octacosanoic acid

Reaction equation

3M h c + M mmcoa DASH S c + 2M nadph c + M tamhexc c −→ M co2 c + M coa c + M h2o c + 2M nadp c + M pmocta c (787)

388 Produced by SBML2LATEX Reactants

Table 705: Properties of each reactant. Id Name SBO M h c H+ M mmcoa DASH S c (S)-Methylmalonyl-CoA M nadph c Nicotinamide adenine dinucleotide phosphate - reduced M tamhexc c tetra-methyl hexacosanoate

Products

Table 706: Properties of each product. Id Name SBO M co2 c CO2 M coa c Coenzyme A M h2o c H2O M nadp c Nicotinamide adenine dinucleotide phosphate M pmocta c penta-methyl octacosanoate

Kinetic Law

v394 = not speciﬁed (788)

6.395 Reaction R FASm300 This is an irreversible reaction of four reactants forming ﬁve products.

Name fatty acid synthase - hexa-methyl triacontanoic acid

Reaction equation 3M h c + M mmcoa DASH S c + 2M nadph c + M pmocta c −→ M co2 c + M coa c + M h2o c + M hmtria c + 2M nadp c (789)

Reactants

Table 707: Properties of each reactant. Id Name SBO M h c H+

Produced by SBML2LATEX 389 Id Name SBO M mmcoa DASH S c (S)-Methylmalonyl-CoA M nadph c Nicotinamide adenine dinucleotide phosphate - reduced M pmocta c penta-methyl octacosanoate

Products

Table 708: Properties of each product. Id Name SBO M co2 c CO2 M coa c Coenzyme A M h2o c H2O M hmtria c hexa-methyl triacontanoic acid (C30:0, plus 6 methyl branches) M nadp c Nicotinamide adenine dinucleotide phosphate

Kinetic Law

v395 = not speciﬁed (790)

6.396 Reaction R FASm3001 This is an irreversible reaction of four reactants forming ﬁve products.

Name fatty acid synthase - octa-methyl dotriacontanoic acid

Reaction equation 3M h c + M hpmtria c + M mmcoa DASH S c + 2M nadph c −→ M co2 c + M coa c + M h2o c + 2M nadp c + M omdtria c (791)

Reactants

Table 709: Properties of each reactant. Id Name SBO M h c H+ M hpmtria c hepta-methyl triacontanoic acid (C30:0, plus 7 methyl branches) M mmcoa DASH S c (S)-Methylmalonyl-CoA M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

390 Produced by SBML2LATEX Products

Table 710: Properties of each product. Id Name SBO M co2 c CO2 M coa c Coenzyme A M h2o c H2O M nadp c Nicotinamide adenine dinucleotide phosphate M omdtria c octa-methyl dotriacontanoic acid (C32:0 with 7 methyl branches)

Kinetic Law

v396 = not speciﬁed (792)

6.397 Reaction R FASm320 This is an irreversible reaction of four reactants forming ﬁve products.

Name fatty acid synthase - hepta-methyl dotriacontanoic acid

Reaction equation 3M h c + M hmtria c + M mmcoa DASH S c + 2M nadph c −→ M co2 c + M coa c + M h2o c + M hpmdtria c + 2M nadp c (793)

Reactants

Table 711: Properties of each reactant. Id Name SBO M h c H+ M hmtria c hexa-methyl triacontanoic acid (C30:0, plus 6 methyl branches) M mmcoa DASH S c (S)-Methylmalonyl-CoA M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

Products

Table 712: Properties of each product. Id Name SBO M co2 c CO2

Produced by SBML2LATEX 391 Id Name SBO M coa c Coenzyme A M h2o c H2O M hpmdtria c hepta-methyl dotriacontanoic acid (7 methyl branches) M nadp c Nicotinamide adenine dinucleotide phosphate

Kinetic Law

v397 = not speciﬁed (794)

6.398 Reaction R FASm340 This is an irreversible reaction of four reactants forming ﬁve products.

Name fatty acid synthase - octa-methyl tetracontatricosanoic acid

Reaction equation 3M h c + M hpmdtria c + M mmcoa DASH S c + 2M nadph c −→ M co2 c + M coa c + M h2o c + 2M nadp c + M omtta c (795)

Reactants

Table 713: Properties of each reactant. Id Name SBO M h c H+ M hpmdtria c hepta-methyl dotriacontanoic acid (7 methyl branches) M mmcoa DASH S c (S)-Methylmalonyl-CoA M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

Products

Table 714: Properties of each product. Id Name SBO M co2 c CO2 M coa c Coenzyme A M h2o c H2O M nadp c Nicotinamide adenine dinucleotide phosphate M omtta c octa-methyl tetracontatricosanoic acid (C34:0, 8 methyl-branched carbons)

392 Produced by SBML2LATEX Kinetic Law

v398 = not speciﬁed (796)

6.399 Reaction R FBA This is a reversible reaction of one reactant forming two products.

Name fructose-bisphosphate aldolase

Reaction equation M fdp c )−−−−* M dhap c + M g3p c (797)

Reactant

Table 715: Properties of each reactant. Id Name SBO M fdp c D-Fructose 1,6-bisphosphate

Products

Table 716: Properties of each product. Id Name SBO M dhap c Dihydroxyacetone phosphate M g3p c Glyceraldehyde 3-phosphate

Kinetic Law

v399 = not speciﬁed (798)

6.400 Reaction R FBP This is an irreversible reaction of two reactants forming two products.

Name fructose-bisphosphatase

Reaction equation

M fdp c + M h2o c −→ M f6p c + M pi c (799)

Produced by SBML2LATEX 393 Reactants

394 Produced by SBML2LATEX Table 717: Properties of each reactant. Id Name SBO M fdp c D-Fructose 1,6-bisphosphate M h2o c H2O

Products

Table 718: Properties of each product. Id Name SBO M f6p c D-Fructose 6-phosphate M pi c Phosphate

Kinetic Law

v400 = not speciﬁed (800)

6.401 Reaction R FCLPA This is a reversible reaction of one reactant forming two products.

Name L-fuculose 1-phosphate aldolase

Reaction equation M fc1p c )−−−−* M dhap c + M lald DASH L c (801)

Reactant

Table 719: Properties of each reactant. Id Name SBO M fc1p c L-Fuculose 1-phosphate

Products

Table 720: Properties of each product. Id Name SBO M dhap c Dihydroxyacetone phosphate M lald DASH L c L-Lactaldehyde

Produced by SBML2LATEX 395 Id Name SBO

Kinetic Law

v401 = not speciﬁed (802)

6.402 Reaction R FCLT This is an irreversible reaction of two reactants forming two products.

Name Ferrochelatase

Reaction equation M fe2 c + M ppp9 c −→ 2M h c + M pheme c (803)

Reactants

Table 721: Properties of each reactant. Id Name SBO M fe2 c Fe2+ M ppp9 c Protoporphyrin

Products

Table 722: Properties of each product. Id Name SBO M h c H+ M pheme c Protoheme

Kinetic Law

v402 = not speciﬁed (804)

6.403 Reaction R FCLT2 This is an irreversible reaction of two reactants forming three products.

Name Ferrochelatase

396 Produced by SBML2LATEX Reaction equation M fmcbtt c + M ppp9 c −→ 2M h c + M mcbtt c + M pheme c (805)

Reactants

Table 723: Properties of each reactant. Id Name SBO M fmcbtt c Iron(II) mycobactin T M ppp9 c Protoporphyrin

Products

Table 724: Properties of each product. Id Name SBO M h c H+ M mcbtt c mycobactin T M pheme c Protoheme

Kinetic Law

v403 = not speciﬁed (806)

6.404 Reaction R FCOAH2 This is an irreversible reaction of two reactants forming three products.

Name formyl coa hydrolase

Reaction equation M forcoa c + M h2o c −→ M coa c + M for c + M h c (807)

Reactants

Table 725: Properties of each reactant. Id Name SBO M forcoa c Formyl-CoA M h2o c H2O

Produced by SBML2LATEX 397 Products

Table 726: Properties of each product. Id Name SBO M coa c Coenzyme A M for c Formate M h c H+

Kinetic Law

v404 = not speciﬁed (808)

6.405 Reaction R FDH This is an irreversible reaction of two reactants forming two products.

Name formate dehydrogenase

Reaction equation M for c + M nad c −→ M co2 c + M nadh c (809)

Reactants

Table 727: Properties of each reactant. Id Name SBO M for c Formate M nad c Nicotinamide adenine dinucleotide

Products

Table 728: Properties of each product. Id Name SBO M co2 c CO2 M nadh c Nicotinamide adenine dinucleotide - reduced

Kinetic Law

v405 = not speciﬁed (810)

398 Produced by SBML2LATEX 6.406 Reaction R FE2abc This is an irreversible reaction of three reactants forming four products.

Name iron (II) transport via ABC system

Reaction equation M atp c + M fe2 e + M h2o c −→ M adp c + M fe2 c + M h c + M pi c (811)

Reactants

Table 729: Properties of each reactant. Id Name SBO M atp c ATP M fe2 e Fe2+ M h2o c H2O

Products

Table 730: Properties of each product. Id Name SBO M adp c ADP M fe2 c Fe2+ M h c H+ M pi c Phosphate

Kinetic Law

v406 = not speciﬁed (812)

6.407 Reaction R FE3Ri This is an irreversible reaction of two reactants forming three products.

Name Fe(III) reduction

Reaction equation

M fadh2 c + 2M fe3 c −→ M fad c + 2M fe2 c + 2M h c (813)

Produced by SBML2LATEX 399 Reactants

400 Produced by SBML2LATEX Table 731: Properties of each reactant. Id Name SBO M fadh2 c Flavin adenine dinucleotide reduced M fe3 c Fe3+

Products

Table 732: Properties of each product. Id Name SBO M fad c Flavin adenine dinucleotide oxidized M fe2 c Fe2+ M h c H+

Kinetic Law

v407 = not speciﬁed (814)

6.408 Reaction R FE3abc This is an irreversible reaction of three reactants forming four products.

Name iron (III) transport via ABC system

Reaction equation M atp c + M fe3 e + M h2o c −→ M adp c + M fe3 c + M h c + M pi c (815)

Reactants

Table 733: Properties of each reactant. Id Name SBO M atp c ATP M fe3 e Fe3+ M h2o c H2O

Products

Produced by SBML2LATEX 401 Table 734: Properties of each product. Id Name SBO M adp c ADP M fe3 c Fe3+ M h c H+ M pi c Phosphate

Kinetic Law

v408 = not speciﬁed (816)

6.409 Reaction R FETRANS This is a reversible reaction of one reactant forming two products.

Name Mycobactin Fe transfer

Reaction equation M fmcbtt c )−−−−* M fe2 c + M mcbtt c (817)

Reactant

Table 735: Properties of each reactant. Id Name SBO M fmcbtt c Iron(II) mycobactin T

Products

Table 736: Properties of each product. Id Name SBO M fe2 c Fe2+ M mcbtt c mycobactin T

Kinetic Law

v409 = not speciﬁed (818)

402 Produced by SBML2LATEX 6.410 Reaction R FHL This is an irreversible reaction of two reactants forming two products.

Name Formate-hydrogen lyase

Reaction equation M for c + M h c −→ M co2 c + M h2 c (819)

Reactants

Table 737: Properties of each reactant. Id Name SBO M for c Formate M h c H+

Products

Table 738: Properties of each product. Id Name SBO M co2 c CO2 M h2 c H2

Kinetic Law

v410 = not speciﬁed (820)

6.411 Reaction R FMETTRS This is an irreversible reaction of two reactants forming three products.

Name Methionyl-tRNA formyltransferase

Reaction equation M 10fthf c + M mettrna c −→ M fmettrna c + M h c + M thf c (821)

Reactants

Produced by SBML2LATEX 403 Table 739: Properties of each reactant. Id Name SBO M 10fthf c 10-Formyltetrahydrofolate M mettrna c L-Methionyl-tRNA (Met)

Products

Table 740: Properties of each product. Id Name SBO M fmettrna c N-Formylmethionyl-tRNA M h c H+ M thf c 5,6,7,8-Tetrahydrofolate

Kinetic Law

v411 = not speciﬁed (822)

6.412 Reaction R FMNAT This is an irreversible reaction of three reactants forming two products.

Name FMN adenylyltransferase

Reaction equation M atp c + M fmn c + M h c −→ M fad c + M ppi c (823)

Reactants

Table 741: Properties of each reactant. Id Name SBO M atp c ATP M fmn c FMN M h c H+

Products

404 Produced by SBML2LATEX Table 742: Properties of each product. Id Name SBO M fad c Flavin adenine dinucleotide oxidized M ppi c Diphosphate

Kinetic Law

v412 = not speciﬁed (824)

6.413 Reaction R FOLD3 This is an irreversible reaction of two reactants forming two products.

Name dihydropteroate synthase

Reaction equation M 2ahhmd c + M 4abz c −→ M dhpt c + M ppi c (825)

Reactants

Table 743: Properties of each reactant. Id Name SBO M 2ahhmd c 2-Amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate M 4abz c 4-Aminobenzoate

Products

Table 744: Properties of each product. Id Name SBO M dhpt c Dihydropteroate M ppi c Diphosphate

Kinetic Law

v413 = not speciﬁed (826)

6.414 Reaction R FOLR2 This is an irreversible reaction of two reactants forming two products.

Produced by SBML2LATEX 405 Name folate reductase

Reaction equation M fol c + M nadph c −→ M dhf c + M nadp c (827)

Reactants

Table 745: Properties of each reactant. Id Name SBO M fol c Folate M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

Products

Table 746: Properties of each product. Id Name SBO M dhf c 7,8-Dihydrofolate M nadp c Nicotinamide adenine dinucleotide phosphate

Kinetic Law

v414 = not speciﬁed (828)

6.415 Reaction R FOMETR This is a reversible reaction of two reactants forming two products.

Name aminomethyltransferase

Reaction equation M 5fthf c + M h c )−−−−* M h2o c + M methf c (829)

Reactants

Table 747: Properties of each reactant. Id Name SBO M 5fthf c 5-Formyltetrahydrofolate M h c H+

406 Produced by SBML2LATEX Products

Table 748: Properties of each product. Id Name SBO M h2o c H2O M methf c 5,10-Methenyltetrahydrofolate

Kinetic Law

v415 = not speciﬁed (830)

6.416 Reaction R FORMCOAL This is a reversible reaction of three reactants forming three products.

Name formyl-coa–CoA ligase

Reaction equation M atp c + M coa c + M for c )−−−−* M amp c + M forcoa c + M ppi c (831)

Reactants

Table 749: Properties of each reactant. Id Name SBO M atp c ATP M coa c Coenzyme A M for c Formate

Products

Table 750: Properties of each product. Id Name SBO M amp c AMP M forcoa c Formyl-CoA M ppi c Diphosphate

Produced by SBML2LATEX 407 Kinetic Law

v416 = not speciﬁed (832)

6.417 Reaction R FRD This is an irreversible reaction of two reactants forming two products.

Name fumarate reductase

Reaction equation M fadh2 c + M fum c −→ M fad c + M succ c (833)

Reactants

Table 751: Properties of each reactant. Id Name SBO M fadh2 c Flavin adenine dinucleotide reduced M fum c Fumarate

Products

Table 752: Properties of each product. Id Name SBO M fad c Flavin adenine dinucleotide oxidized M succ c Succinate

Kinetic Law

v417 = not speciﬁed (834)

6.418 Reaction R FRD2 This is an irreversible reaction of two reactants forming two products.

Name fumarate reductase

Reaction equation M fum c + M mql8 c −→ M mqn8 c + M succ c (835)

408 Produced by SBML2LATEX Reactants

Table 753: Properties of each reactant. Id Name SBO M fum c Fumarate M mql8 c Menaquinol 8

Products

Table 754: Properties of each product. Id Name SBO M mqn8 c Menaquinone 8 M succ c Succinate

Kinetic Law

v418 = not speciﬁed (836)

6.419 Reaction R FRD3 This is an irreversible reaction of two reactants forming two products.

Name fumarate reductase

Reaction equation M 2dmmql8 c + M fum c −→ M 2dmmq8 c + M succ c (837)

Reactants

Table 755: Properties of each reactant. Id Name SBO M 2dmmql8 c 2-Demethylmenaquinol 8 M fum c Fumarate

Products

Produced by SBML2LATEX 409 Table 756: Properties of each product. Id Name SBO M 2dmmq8 c 2-Demethylmenaquinone 8 M succ c Succinate

Kinetic Law

v419 = not speciﬁed (838)

6.420 Reaction R FRD5 This is a reversible reaction of two reactants forming two products.

Name fumarate reductase

Reaction equation M fum c + M mql6 c )−−−−* M mqn6 c + M succ c (839)

Reactants

Table 757: Properties of each reactant. Id Name SBO M fum c Fumarate M mql6 c Menaquinol 6

Products

Table 758: Properties of each product. Id Name SBO M mqn6 c Menaquinone 6 M succ c Succinate

Kinetic Law

v420 = not speciﬁed (840)

6.421 Reaction R FRDO2r This is a reversible reaction of two reactants forming two products.

410 Produced by SBML2LATEX Name ferredoxin oxidoreductase

Reaction equation M adfdRD c + 2M nadp c )−−−−* M adfdOX c + 2M nadph c (841)

Reactants

Table 759: Properties of each reactant. Id Name SBO M adfdRD c Reduced adrenal ferredoxin M nadp c Nicotinamide adenine dinucleotide phosphate

Products

Table 760: Properties of each product. Id Name SBO M adfdOX c Oxidized adrenal ferredoxin M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

Kinetic Law

v421 = not speciﬁed (842)

6.422 Reaction R FRDO3r This is a reversible reaction of two reactants forming two products.

Name ferredoxin oxidoreductase

Reaction equation M adfdRD c + 2M nad c )−−−−* M adfdOX c + 2M nadh c (843)

Reactants

Table 761: Properties of each reactant. Id Name SBO M adfdRD c Reduced adrenal ferredoxin M nad c Nicotinamide adenine dinucleotide

Produced by SBML2LATEX 411 Products

Table 762: Properties of each product. Id Name SBO M adfdOX c Oxidized adrenal ferredoxin M nadh c Nicotinamide adenine dinucleotide - reduced

Kinetic Law

v422 = not speciﬁed (844)

6.423 Reaction R FRDOr This is a reversible reaction of two reactants forming three products.

Name ferredoxin oxidoreductase

Reaction equation M fdxrd c + M nadp c )−−−−* M fdxox c + M h c + M nadph c (845)

Reactants

Table 763: Properties of each reactant. Id Name SBO M fdxrd c Reduced ferredoxin M nadp c Nicotinamide adenine dinucleotide phosphate

Products

Table 764: Properties of each product. Id Name SBO M fdxox c Oxidized ferredoxin M h c H+ M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

Kinetic Law

v423 = not speciﬁed (846)

412 Produced by SBML2LATEX 6.424 Reaction R FRRPPDIMAS This is an irreversible reaction of two reactants forming three products.

Name fucose rhamnose rhamnose phenol phthiocerol dimycocerosate synthesis

Reaction equation M gdpfuc c + M rrppdima c −→ M frrppdima c + M gdp c + M h c (847)

Reactants

Table 765: Properties of each reactant. Id Name SBO M gdpfuc c GDP-L-fucose M rrppdima c rhamnose rhamnose phenol phthiocerol dimycocerosate (Mtb)

Products

Table 766: Properties of each product. Id Name SBO M frrppdima c fucose rhamnose rhamnose phenol phthiocerol dimycocerosate (Mtb) M gdp c GDP M h c H+

Kinetic Law

v424 = not speciﬁed (848)

6.425 Reaction R FTHFCL This is an irreversible reaction of two reactants forming three products.

Name 5-formethyltetrahydrofolate cyclo-ligase

Reaction equation M 5fthf c + M atp c −→ M adp c + M methf c + M pi c (849)

Reactants

Produced by SBML2LATEX 413 Table 767: Properties of each reactant. Id Name SBO M 5fthf c 5-Formyltetrahydrofolate M atp c ATP

Products

Table 768: Properties of each product. Id Name SBO M adp c ADP M methf c 5,10-Methenyltetrahydrofolate M pi c Phosphate

Kinetic Law

v425 = not speciﬁed (850)

6.426 Reaction R FTHFD This is an irreversible reaction of two reactants forming three products.

Name formyltetrahydrofolate deformylase

Reaction equation M 10fthf c + M h2o c −→ M for c + M h c + M thf c (851)

Reactants

Table 769: Properties of each reactant. Id Name SBO M 10fthf c 10-Formyltetrahydrofolate M h2o c H2O

Products

414 Produced by SBML2LATEX Table 770: Properties of each product. Id Name SBO M for c Formate M h c H+ M thf c 5,6,7,8-Tetrahydrofolate

Kinetic Law

v426 = not speciﬁed (852)

6.427 Reaction R FTHFL This is a reversible reaction of three reactants forming three products.

Name formate-tetrahydrofolate ligase

Reaction equation M atp c + M for c + M thf c )−−−−* M 10fthf c + M adp c + M pi c (853)

Reactants

Table 771: Properties of each reactant. Id Name SBO M atp c ATP M for c Formate M thf c 5,6,7,8-Tetrahydrofolate

Products

Table 772: Properties of each product. Id Name SBO M 10fthf c 10-Formyltetrahydrofolate M adp c ADP M pi c Phosphate

Kinetic Law

v427 = not speciﬁed (854)

Produced by SBML2LATEX 415 6.428 Reaction R FUM This is a reversible reaction of two reactants forming one product.

Name fumarase

Reaction equation M fum c + M h2o c )−−−−* M mal DASH L c (855)

Reactants

Table 773: Properties of each reactant. Id Name SBO M fum c Fumarate M h2o c H2O

Product

Table 774: Properties of each product. Id Name SBO M mal DASH L c L-Malate

Kinetic Law

v428 = not speciﬁed (856)

6.429 Reaction R FUMt2r This is a reversible reaction of two reactants forming two products.

Name fumarate reversible transport via symport

Reaction equation M fum e + M h e )−−−−* M fum c + M h c (857)

Reactants

416 Produced by SBML2LATEX Table 775: Properties of each reactant. Id Name SBO M fum e Fumarate M h e H+

Products

Table 776: Properties of each product. Id Name SBO M fum c Fumarate M h c H+

Kinetic Law

v429 = not speciﬁed (858)

6.430 Reaction R G16MTM1 This is an irreversible reaction of two reactants forming three products.

Name Glycolipid 1,6-alpha-D-mannosyltransferase

Reaction equation M gdpmann c + M ptd1ino160190 c −→ M PIM1 c + M gdp c + M h c (859)

Reactants

Table 777: Properties of each reactant. Id Name SBO M gdpmann c GDP-D-mannose M ptd1ino160190 c phosphatidyl 1D myo inositol (C16:0, C19:0)

Products

Table 778: Properties of each product. Id Name SBO M PIM1 c phosphatidylinositol mannoside (tuberculosis)

Produced by SBML2LATEX 417 Id Name SBO M gdp c GDP M h c H+

Kinetic Law

v430 = not speciﬁed (860)

6.431 Reaction R G16MTM10 This is an irreversible reaction of two reactants forming three products.

Name Glycolipid 16-alpha-D-mannosyltransferase

Reaction equation M PIM5 c + M gdpmann c −→ M PIM6 c + M gdp c + M h c (861)

Reactants

Table 779: Properties of each reactant. Id Name SBO M PIM5 c phosphatidylinositol mannoside penta-mannose (tuberculosis) M gdpmann c GDP-D-mannose

Products

Table 780: Properties of each product. Id Name SBO M PIM6 c phosphatidylinositol mannoside hexa-mannose (tuberculosis) M gdp c GDP M h c H+

Kinetic Law

v431 = not speciﬁed (862)

6.432 Reaction R G16MTM2 This is an irreversible reaction of two reactants forming three products.

418 Produced by SBML2LATEX Name Glycolipid 16-alpha-D-mannosyltransferase

Reaction equation M Ac1PIM1 c + M gdpmann c −→ M Ac1PIM2 c + M gdp c + M h c (863)

Reactants

Table 781: Properties of each reactant. Id Name SBO M Ac1PIM1 c acyl phosphatidylinositol mannoside (tuberculosis) M gdpmann c GDP-D-mannose

Products

Table 782: Properties of each product. Id Name SBO M Ac1PIM2 c acyl phosphatidylinositol mannoside di-mannose (tuberculosis) M gdp c GDP M h c H+

Kinetic Law

v432 = not speciﬁed (864)

6.433 Reaction R G16MTM4 This is an irreversible reaction of two reactants forming three products.

Name Glycolipid 16-alpha-D-mannosyltransferase

Reaction equation M Ac1PIM2 c + M decdman1p tb c −→ M Ac1PIM3 c + M decd tb c + M h c (865)

Reactants

Produced by SBML2LATEX 419 Table 783: Properties of each reactant. Id Name SBO M Ac1PIM2 c acyl phosphatidylinositol mannoside di-mannose (tuberculosis) M decdman1p tb c (E,E,E,E,E,E,E,Z,Z) decaprenyl mannose phosphate

Products

Table 784: Properties of each product. Id Name SBO M Ac1PIM3 c acyl phosphatidylinositol mannoside tri-mannose (tuberculosis) M decd tb c (E,E,E,E,E,E,E,Z,Z) decaprenyl phosphate M h c H+

Kinetic Law

v433 = not speciﬁed (866)

6.434 Reaction R G16MTM5 This is an irreversible reaction of two reactants forming three products.

Name Glycolipid 16-alpha-D-mannosyltransferase

Reaction equation M Ac1PIM3 c + M decdman1p tb c −→ M Ac1PIM4 c + M decd tb c + M h c (867)

Reactants

Table 785: Properties of each reactant. Id Name SBO M Ac1PIM3 c acyl phosphatidylinositol mannoside tri-mannose (tuberculosis) M decdman1p tb c (E,E,E,E,E,E,E,Z,Z) decaprenyl mannose phosphate

Products

420 Produced by SBML2LATEX Table 786: Properties of each product. Id Name SBO M Ac1PIM4 c acyl phosphatidylinositol mannoside tetra-mannose (tuberculosis) M decd tb c (E,E,E,E,E,E,E,Z,Z) decaprenyl phosphate M h c H+

Kinetic Law

v434 = not speciﬁed (868)

6.435 Reaction R G16MTM6 This is an irreversible reaction of two reactants forming three products.

Name Glycolipid 16-alpha-D-mannosyltransferase

Reaction equation M PIM1 c + M gdpmann c −→ M PIM2 c + M gdp c + M h c (869)

Reactants

Table 787: Properties of each reactant. Id Name SBO M PIM1 c phosphatidylinositol mannoside (tuberculosis) M gdpmann c GDP-D-mannose

Products

Table 788: Properties of each product. Id Name SBO M PIM2 c phosphatidylinositol mannoside di-mannose (tuberculosis) M gdp c GDP M h c H+

Kinetic Law

v435 = not speciﬁed (870)

Produced by SBML2LATEX 421 6.436 Reaction R G16MTM7 This is an irreversible reaction of two reactants forming three products.

Name Glycolipid 16-alpha-D-mannosyltransferase

Reaction equation M PIM2 c + M gdpmann c −→ M PIM3 c + M gdp c + M h c (871)

Reactants

Table 789: Properties of each reactant. Id Name SBO M PIM2 c phosphatidylinositol mannoside di-mannose (tuberculosis) M gdpmann c GDP-D-mannose

Products

Table 790: Properties of each product. Id Name SBO M PIM3 c phosphatidylinositol mannoside tri-mannose (tuberculosis) M gdp c GDP M h c H+

Kinetic Law

v436 = not speciﬁed (872)

6.437 Reaction R G16MTM8 This is an irreversible reaction of two reactants forming three products.

Name Glycolipid 16-alpha-D-mannosyltransferase

Reaction equation M PIM3 c + M gdpmann c −→ M PIM4 c + M gdp c + M h c (873)

Reactants

422 Produced by SBML2LATEX Table 791: Properties of each reactant. Id Name SBO M PIM3 c phosphatidylinositol mannoside tri-mannose (tuberculosis) M gdpmann c GDP-D-mannose

Products

Table 792: Properties of each product. Id Name SBO M PIM4 c phosphatidylinositol mannoside tetra-mannose (tuberculosis) M gdp c GDP M h c H+

Kinetic Law

v437 = not speciﬁed (874)

6.438 Reaction R G16MTM9 This is an irreversible reaction of two reactants forming three products.

Name Glycolipid 16-alpha-D-mannosyltransferase

Reaction equation M PIM4 c + M gdpmann c −→ M PIM5 c + M gdp c + M h c (875)

Reactants

Table 793: Properties of each reactant. Id Name SBO M PIM4 c phosphatidylinositol mannoside tetra-mannose (tuberculosis) M gdpmann c GDP-D-mannose

Products

Produced by SBML2LATEX 423 Table 794: Properties of each product. Id Name SBO M PIM5 c phosphatidylinositol mannoside penta-mannose (tuberculosis) M gdp c GDP M h c H+

Kinetic Law

v438 = not speciﬁed (876)

6.439 Reaction R G1PACT This is an irreversible reaction of two reactants forming three products.

Name glucosamine-1-phosphate N-acetyltransferase

Reaction equation M accoa c + M gam1p c −→ M acgam1p c + M coa c + M h c (877)

Reactants

Table 795: Properties of each reactant. Id Name SBO M accoa c Acetyl-CoA M gam1p c D-Glucosamine 1-phosphate

Products

Table 796: Properties of each product. Id Name SBO M acgam1p c N-Acetyl-D-glucosamine 1-phosphate M coa c Coenzyme A M h c H+

Kinetic Law

v439 = not speciﬁed (878)

424 Produced by SBML2LATEX 6.440 Reaction R G1PTT This is an irreversible reaction of three reactants forming two products.

Name glucose-1-phosphate thymidylyltransferase

Reaction equation M dttp c + M g1p c + M h c −→ M dtdpglu c + M ppi c (879)

Reactants

Table 797: Properties of each reactant. Id Name SBO M dttp c dTTP M g1p c D-Glucose 1-phosphate M h c H+

Products

Table 798: Properties of each product. Id Name SBO M dtdpglu c dTDPglucose M ppi c Diphosphate

Kinetic Law

v440 = not speciﬁed (880)

6.441 Reaction R G1SATi This is an irreversible reaction of one reactant forming one product.

Name glutamate-1-semialdehyde aminotransferase

Reaction equation M glu1sa c −→ M 5aop c (881)

Reactant

Produced by SBML2LATEX 425 Table 799: Properties of each reactant. Id Name SBO M glu1sa c L-Glutamate 1-semialdehyde

Product

Table 800: Properties of each product. Id Name SBO M 5aop c 5-Amino-4-oxopentanoate

Kinetic Law

v441 = not speciﬁed (882)

6.442 Reaction R G3PAT160 This is an irreversible reaction of two reactants forming two products.

Name glycerol-3-phosphate acyltransferase (C16:0)

Reaction equation M glyc3p c + M palmACP c −→ M 1hdecg3p c + M ACP c (883)

Reactants

Table 801: Properties of each reactant. Id Name SBO M glyc3p c Glycerol 3-phosphate M palmACP c Palmitoyl-ACP (n-C16:0ACP)

Products

Table 802: Properties of each product. Id Name SBO M 1hdecg3p c 1-hexadecanoyl-sn-glycerol 3-phosphate M ACP c acyl carrier protein

426 Produced by SBML2LATEX Kinetic Law

v442 = not speciﬁed (884)

6.443 Reaction R G3PAT190 This is an irreversible reaction of two reactants forming two products.

Name glycerol-3-phosphate acyltransferase (C19:0)

Reaction equation M glyc3p c + M mstrACP c −→ M 1msg3p c + M ACP c (885)

Reactants

Table 803: Properties of each reactant. Id Name SBO M glyc3p c Glycerol 3-phosphate M mstrACP c 10methyl stearyoyl-ACP

Products

Table 804: Properties of each product. Id Name SBO M 1msg3p c 1-Acyl-sn-glycerol 3-phosphate (branched C19:0) M ACP c acyl carrier protein

Kinetic Law

v443 = not speciﬁed (886)

6.444 Reaction R G3PD1 This is a reversible reaction of two reactants forming three products.

Name glycerol-3-phosphate dehydrogenase (NAD)

Reaction equation

M glyc3p c + M nad c )−−−−* M dhap c + M h c + M nadh c (887)

Produced by SBML2LATEX 427 Reactants

Table 805: Properties of each reactant. Id Name SBO M glyc3p c Glycerol 3-phosphate M nad c Nicotinamide adenine dinucleotide

Products

Table 806: Properties of each product. Id Name SBO M dhap c Dihydroxyacetone phosphate M h c H+ M nadh c Nicotinamide adenine dinucleotide - reduced

Kinetic Law

v444 = not speciﬁed (888)

6.445 Reaction R G5SADs This is an irreversible reaction of one reactant forming three products.

Name L-glutamate 5-semialdehyde dehydratase (spontaneous)

Reaction equation M glu5sa c −→ M 1pyr5c c + M h2o c + M h c (889)

Reactant

Table 807: Properties of each reactant. Id Name SBO M glu5sa c L-Glutamate 5-semialdehyde

Products

428 Produced by SBML2LATEX Table 808: Properties of each product. Id Name SBO M 1pyr5c c 1-Pyrroline-5-carboxylate M h2o c H2O M h c H+

Kinetic Law

v445 = not speciﬁed (890)

6.446 Reaction R G5SD This is an irreversible reaction of three reactants forming three products.

Name glutamate-5-semialdehyde dehydrogenase

Reaction equation M glu5p c + M h c + M nadph c −→ M glu5sa c + M nadp c + M pi c (891)

Reactants

Table 809: Properties of each reactant. Id Name SBO M glu5p c L-Glutamate 5-phosphate M h c H+ M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

Products

Table 810: Properties of each product. Id Name SBO M glu5sa c L-Glutamate 5-semialdehyde M nadp c Nicotinamide adenine dinucleotide phosphate M pi c Phosphate

Kinetic Law

v446 = not speciﬁed (892)

Produced by SBML2LATEX 429 6.447 Reaction R G5SD2 This is an irreversible reaction of three reactants forming three products.

Name glutamate-5-semialdehyde dehydrogenase

Reaction equation M glu5p c + M h c + M nadh c −→ M glu5sa c + M nad c + M pi c (893)

Reactants

Table 811: Properties of each reactant. Id Name SBO M glu5p c L-Glutamate 5-phosphate M h c H+ M nadh c Nicotinamide adenine dinucleotide - reduced

Products

Table 812: Properties of each product. Id Name SBO M glu5sa c L-Glutamate 5-semialdehyde M nad c Nicotinamide adenine dinucleotide M pi c Phosphate

Kinetic Law

v447 = not speciﬁed (894)

6.448 Reaction R G6PDH2 This is an irreversible reaction of two reactants forming three products.

Name glucose 6-phosphate dehydrogenase

Reaction equation M g6p c + M nadp c −→ M 6pgl c + M h c + M nadph c (895)

Reactants

430 Produced by SBML2LATEX Table 813: Properties of each reactant. Id Name SBO M g6p c D-Glucose 6-phosphate M nadp c Nicotinamide adenine dinucleotide phosphate

Products

Table 814: Properties of each product. Id Name SBO M 6pgl c 6-phospho-D-glucono-1,5-lactone M h c H+ M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

Kinetic Law

v448 = not speciﬁed (896)

6.449 Reaction R GALFT This is an irreversible reaction of three reactants forming three products.

Name galactofuranose transferse (M tb)

Reaction equation M h2o c + M ragund c + 30M udpgalfur c −→ M galfragund c + 30M h c + 30M udp c (897)

Reactants

Table 815: Properties of each reactant. Id Name SBO M h2o c H2O M ragund c rhamanosyl-N-acetylglucosamyl-undecaprenyl diphosphate M udpgalfur c UDP-D-galacto-1,4-furanose

Products

Produced by SBML2LATEX 431 Table 816: Properties of each product. Id Name SBO M galfragund c galactofuranosyl(30)-rhamanosyl-N-acetylglucosamyl-undecaprenyl diphosphate (M tb) M h c H+ M udp c UDP

Kinetic Law

v449 = not speciﬁed (898)

6.450 Reaction R GALKr This is a reversible reaction of two reactants forming three products.

Name galactokinase

Reaction equation M atp c + M gal c )−−−−* M adp c + M gal1p c + M h c (899)

Reactants

Table 817: Properties of each reactant. Id Name SBO M atp c ATP M gal c D-Galactose

Products

Table 818: Properties of each product. Id Name SBO M adp c ADP M gal1p c alpha-D-Galactose 1-phosphate M h c H+

Kinetic Law

v450 = not speciﬁed (900)

432 Produced by SBML2LATEX 6.451 Reaction R GALT This is a reversible reaction of three reactants forming two products.

Name galactose-1-phosphate uridylyltransferase

Reaction equation M gal1p c + M h c + M utp c )−−−−* M ppi c + M udpgal c (901)

Reactants

Table 819: Properties of each reactant. Id Name SBO M gal1p c alpha-D-Galactose 1-phosphate M h c H+ M utp c UTP

Products

Table 820: Properties of each product. Id Name SBO M ppi c Diphosphate M udpgal c UDPgalactose

Kinetic Law

v451 = not speciﬁed (902)

6.452 Reaction R GALUi This is an irreversible reaction of three reactants forming two products.

Name UTP-glucose-1-phosphate uridylyltransferase (irreversible)

Reaction equation M g1p c + M h c + M utp c −→ M ppi c + M udpg c (903)

Reactants

Produced by SBML2LATEX 433 Table 821: Properties of each reactant. Id Name SBO M g1p c D-Glucose 1-phosphate M h c H+ M utp c UTP

Products

Table 822: Properties of each product. Id Name SBO M ppi c Diphosphate M udpg c UDPglucose

Kinetic Law

v452 = not speciﬁed (904)

6.453 Reaction R GALt2 This is an irreversible reaction of two reactants forming two products.

Name D-galactose transport in via proton symport

Reaction equation M gal e + M h e −→ M gal c + M h c (905)

Reactants

Table 823: Properties of each reactant. Id Name SBO M gal e D-Galactose M h e H+

Products

434 Produced by SBML2LATEX Table 824: Properties of each product. Id Name SBO M gal c D-Galactose M h c H+

Kinetic Law

v453 = not speciﬁed (906)

6.454 Reaction R GAPD This is a reversible reaction of three reactants forming three products.

Name glyceraldehyde-3-phosphate dehydrogenase

Reaction equation M g3p c + M nad c + M pi c )−−−−* M 13dpg c + M h c + M nadh c (907)

Reactants

Table 825: Properties of each reactant. Id Name SBO M g3p c Glyceraldehyde 3-phosphate M nad c Nicotinamide adenine dinucleotide M pi c Phosphate

Products

Table 826: Properties of each product. Id Name SBO M 13dpg c 3-Phospho-D-glyceroyl phosphate M h c H+ M nadh c Nicotinamide adenine dinucleotide - reduced

Kinetic Law

v454 = not speciﬁed (908)

Produced by SBML2LATEX 435 6.455 Reaction R GARFT This is a reversible reaction of two reactants forming three products.

Name phosphoribosylglycinamide formyltransferase

Reaction equation M 10fthf c + M gar c )−−−−* M fgam c + M h c + M thf c (909)

Reactants

Table 827: Properties of each reactant. Id Name SBO M 10fthf c 10-Formyltetrahydrofolate M gar c N1-(5-Phospho-D-ribosyl)glycinamide

Products

Table 828: Properties of each product. Id Name SBO M fgam c N2-Formyl-N1-(5-phospho-D-ribosyl)glycinamide M h c H+ M thf c 5,6,7,8-Tetrahydrofolate

Kinetic Law

v455 = not speciﬁed (910)

6.456 Reaction R GCC2 This is an irreversible reaction of two reactants forming three products.

Name glycine-cleavage system (lipoamide) irreversible

Reaction equation M alpam c + M thf c −→ M dhlam c + M mlthf c + M nh4 c (911)

Reactants

436 Produced by SBML2LATEX Table 829: Properties of each reactant. Id Name SBO M alpam c S-aminomethyldihydrolipoamide M thf c 5,6,7,8-Tetrahydrofolate

Products

Table 830: Properties of each product. Id Name SBO M dhlam c Dihydrolipoamide M mlthf c 5,10-Methylenetetrahydrofolate M nh4 c Ammonium

Kinetic Law

v456 = not speciﬁed (912)

6.457 Reaction R GCCa This is an irreversible reaction of three reactants forming two products.

Name glycine-cleavage complex

Reaction equation M gly c + M h c + M lpro c −→ M alpro c + M co2 c (913)

Reactants

Table 831: Properties of each reactant. Id Name SBO M gly c Glycine M h c H+ M lpro c Lipoylprotein

Products

Produced by SBML2LATEX 437 Table 832: Properties of each product. Id Name SBO M alpro c S-Aminomethyldihydrolipoylprotein M co2 c CO2

Kinetic Law

v457 = not speciﬁed (914)

6.458 Reaction R GCCb This is an irreversible reaction of two reactants forming three products.

Name glycine cleavage complex

Reaction equation M alpro c + M thf c −→ M dhlpro c + M mlthf c + M nh4 c (915)

Reactants

Table 833: Properties of each reactant. Id Name SBO M alpro c S-Aminomethyldihydrolipoylprotein M thf c 5,6,7,8-Tetrahydrofolate

Products

Table 834: Properties of each product. Id Name SBO M dhlpro c Dihydrolipolprotein M mlthf c 5,10-Methylenetetrahydrofolate M nh4 c Ammonium

Kinetic Law

v458 = not speciﬁed (916)

438 Produced by SBML2LATEX 6.459 Reaction R GCCc This is an irreversible reaction of two reactants forming three products.

Name glycine-cleavage complex

Reaction equation M dhlpro c + M nad c −→ M h c + M lpro c + M nadh c (917)

Reactants

Table 835: Properties of each reactant. Id Name SBO M dhlpro c Dihydrolipolprotein M nad c Nicotinamide adenine dinucleotide

Products

Table 836: Properties of each product. Id Name SBO M h c H+ M lpro c Lipoylprotein M nadh c Nicotinamide adenine dinucleotide - reduced

Kinetic Law

v459 = not speciﬁed (918)

6.460 Reaction R GF6PTAr This is a reversible reaction of two reactants forming two products.

Name Glutamine-fructose-6-phosphate transaminase

Reaction equation M f6p c + M gln DASH L c )−−−−* M gam6p c + M glu DASH L c (919)

Reactants

Produced by SBML2LATEX 439 Table 837: Properties of each reactant. Id Name SBO M f6p c D-Fructose 6-phosphate M gln DASH L c L-Glutamine

Products

Table 838: Properties of each product. Id Name SBO M gam6p c D-Glucosamine 6-phosphate M glu DASH L c L-Glutamate

Kinetic Law

v460 = not speciﬁed (920)

6.461 Reaction R GFUCS This is an irreversible reaction of three reactants forming two products.

Name GDP-L-fucose synthase

Reaction equation M gdpddman c + M h c + M nadph c −→ M gdpfuc c + M nadp c (921)

Reactants

Table 839: Properties of each reactant. Id Name SBO M gdpddman c GDP-4-dehydro-6-deoxy-D-mannose M h c H+ M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

Products

440 Produced by SBML2LATEX Table 840: Properties of each product. Id Name SBO M gdpfuc c GDP-L-fucose M nadp c Nicotinamide adenine dinucleotide phosphate

Kinetic Law

v461 = not speciﬁed (922)

6.462 Reaction R GGLUCT2 This is an irreversible reaction of one reactant forming two products.

Name gamma-glutamylcyclotransferase

Reaction equation M gluala c −→ M 5oxpro c + M ala DASH L c (923)

Reactant

Table 841: Properties of each reactant. Id Name SBO M gluala c 5-L-Glutamyl-L-alanine

Products

Table 842: Properties of each product. Id Name SBO M 5oxpro c 5-Oxoproline M ala DASH L c L-Alanine

Kinetic Law

v462 = not speciﬁed (924)

6.463 Reaction R GHMT2 This is an irreversible reaction of two reactants forming three products.

Produced by SBML2LATEX 441 Name glycine hydroxymethyltransferase

Reaction equation M ser DASH L c + M thf c −→ M gly c + M h2o c + M mlthf c (925)

Reactants

Table 843: Properties of each reactant. Id Name SBO M ser DASH L c L-Serine M thf c 5,6,7,8-Tetrahydrofolate

Products

Table 844: Properties of each product. Id Name SBO M gly c Glycine M h2o c H2O M mlthf c 5,10-Methylenetetrahydrofolate

Kinetic Law

v463 = not speciﬁed (926)

6.464 Reaction R GK1 This is a reversible reaction of two reactants forming two products.

Name guanylate kinase (GMP:ATP)

Reaction equation M atp c + M gmp c )−−−−* M adp c + M gdp c (927)

Reactants

442 Produced by SBML2LATEX Table 845: Properties of each reactant. Id Name SBO M atp c ATP M gmp c GMP

Products

Table 846: Properties of each product. Id Name SBO M adp c ADP M gdp c GDP

Kinetic Law

v464 = not speciﬁed (928)

6.465 Reaction R GLCP This is an irreversible reaction of two reactants forming one product.

Name glycogen phosphorylase

Reaction equation M glycogen c + M pi c −→ M g1p c (929)

Reactants

Table 847: Properties of each reactant. Id Name SBO M glycogen c glycogen M pi c Phosphate

Product

Table 848: Properties of each product. Id Name SBO M g1p c D-Glucose 1-phosphate

Produced by SBML2LATEX 443 Id Name SBO

Kinetic Law

v465 = not speciﬁed (930)

6.466 Reaction R GLCS1 This is an irreversible reaction of one reactant forming three products.

Name glycogen synthase (ADPGlc)

Reaction equation M adpglc c −→ M adp c + M glycogen c + M h c (931)

Reactant

Table 849: Properties of each reactant. Id Name SBO M adpglc c ADPglucose

Products

Table 850: Properties of each product. Id Name SBO M adp c ADP M glycogen c glycogen M h c H+

Kinetic Law

v466 = not speciﬁed (932)

6.467 Reaction R GLCabc This is an irreversible reaction of three reactants forming four products.

Name D-glucose transport via ABC system

444 Produced by SBML2LATEX Reaction equation M atp c + M glc DASH D e + M h2o c −→ M adp c + M glc DASH D c + M h c + M pi c (933)

Reactants

Table 851: Properties of each reactant. Id Name SBO M atp c ATP M glc DASH D e D-Glucose M h2o c H2O

Products

Table 852: Properties of each product. Id Name SBO M adp c ADP M glc DASH D c D-Glucose M h c H+ M pi c Phosphate

Kinetic Law

v467 = not speciﬁed (934)

6.468 Reaction R GLGC This is an irreversible reaction of three reactants forming two products.

Name glucose-1-phosphate adenylyltransferase

Reaction equation M atp c + M g1p c + M h c −→ M adpglc c + M ppi c (935)

Reactants

Produced by SBML2LATEX 445 Table 853: Properties of each reactant. Id Name SBO M atp c ATP M g1p c D-Glucose 1-phosphate M h c H+

Products

Table 854: Properties of each product. Id Name SBO M adpglc c ADPglucose M ppi c Diphosphate

Kinetic Law

v468 = not speciﬁed (936)

6.469 Reaction R GLNS This is an irreversible reaction of three reactants forming four products.

Name glutamine synthetase

Reaction equation M atp c + M glu DASH L c + M nh4 c −→ M adp c + M gln DASH L c + M h c + M pi c (937)

Reactants

Table 855: Properties of each reactant. Id Name SBO M atp c ATP M glu DASH L c L-Glutamate M nh4 c Ammonium

Products

446 Produced by SBML2LATEX Table 856: Properties of each product. Id Name SBO M adp c ADP M gln DASH L c L-Glutamine M h c H+ M pi c Phosphate

Kinetic Law

v469 = not speciﬁed (938)

6.470 Reaction R GLNSP1 This is an irreversible reaction of three reactants forming four products.

Name glutamine synthetase (uaaAgld)

Reaction equation M atp c + M nh4 c + M uaaAgla c −→ M adp c + M h c + M pi c + M uaaAgtla c (939)

Reactants

Table 857: Properties of each reactant. Id Name SBO M atp c ATP M nh4 c Ammonium M uaaAgla c Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine

Products

Table 858: Properties of each product. Id Name SBO M adp c ADP M h c H+ M pi c Phosphate M uaaAgtla c Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-glutaminyl-L-lysyl-D-alanyl-D-alanine

Produced by SBML2LATEX 447 Kinetic Law

v470 = not speciﬁed (940)

6.471 Reaction R GLNSP2 This is an irreversible reaction of three reactants forming four products.

Name glutamine synthetase (uaaGgla)

Reaction equation M atp c + M nh4 c + M uaaGgla c −→ M adp c + M h c + M pi c + M uaaGgtla c (941)

Reactants

Table 859: Properties of each reactant. Id Name SBO M atp c ATP M nh4 c Ammonium M uaaGgla c Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine

Products

Table 860: Properties of each product. Id Name SBO M adp c ADP M h c H+ M pi c Phosphate M uaaGgtla c Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-isoglutaminyl-L-lysyl-D-alanyl-D-alanine

Kinetic Law

v471 = not speciﬁed (942)

6.472 Reaction R GLNSP3 This is an irreversible reaction of three reactants forming four products.

Name glutamine synthetase (uaagmda)

448 Produced by SBML2LATEX Reaction equation M atp c + M nh4 c + M uaagmda c −→ M adp c + M h c + M pi c + M uaagtmda c (943)

Reactants

Table 861: Properties of each reactant. Id Name SBO M atp c ATP M nh4 c Ammonium M uaagmda c Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-ala-D-glu-meso-2,6-diaminopimeloyl-D-ala-D-ala

Products

Table 862: Properties of each product. Id Name SBO M adp c ADP M h c H+ M pi c Phosphate M uaagtmda c Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-glutaminyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

Kinetic Law

v472 = not speciﬁed (944)

6.473 Reaction R GLU5K This is an irreversible reaction of two reactants forming two products.

Name glutamate 5-kinase

Reaction equation M atp c + M glu DASH L c −→ M adp c + M glu5p c (945)

Reactants

Table 863: Properties of each reactant. Id Name SBO M atp c ATP

Produced by SBML2LATEX 449 Id Name SBO M glu DASH L c L-Glutamate

Products

Table 864: Properties of each product. Id Name SBO M adp c ADP M glu5p c L-Glutamate 5-phosphate

Kinetic Law

v473 = not speciﬁed (946)

6.474 Reaction R GLUCYS This is an irreversible reaction of three reactants forming four products.

Name gamma-glutamylcysteine synthetase

Reaction equation M atp c + M cys DASH L c + M glu DASH L c −→ M adp c + M glucys c + M h c + M pi c (947)

Reactants

Table 865: Properties of each reactant. Id Name SBO M atp c ATP M cys DASH L c L-Cysteine M glu DASH L c L-Glutamate

Products

Table 866: Properties of each product. Id Name SBO M adp c ADP

450 Produced by SBML2LATEX Id Name SBO M glucys c gamma-L-Glutamyl-L-cysteine M h c H+ M pi c Phosphate

Kinetic Law

v474 = not speciﬁed (948)

6.475 Reaction R GLUDC This is an irreversible reaction of two reactants forming two products.

Name Glutamate Decarboxylase

Reaction equation M glu DASH L c + M h c −→ M 4abut c + M co2 c (949)

Reactants

Table 867: Properties of each reactant. Id Name SBO M glu DASH L c L-Glutamate M h c H+

Products

Table 868: Properties of each product. Id Name SBO M 4abut c 4-Aminobutanoate M co2 c CO2

Kinetic Law

v475 = not speciﬁed (950)

6.476 Reaction R GLUDx This is a reversible reaction of three reactants forming four products.

Produced by SBML2LATEX 451 Name glutamate dehydrogenase (NAD)

Reaction equation M glu DASH L c + M h2o c + M nad c )−−−−* M akg c + M h c + M nadh c + M nh4 c (951)

Reactants

Table 869: Properties of each reactant. Id Name SBO M glu DASH L c L-Glutamate M h2o c H2O M nad c Nicotinamide adenine dinucleotide

Products

Table 870: Properties of each product. Id Name SBO M akg c 2-Oxoglutarate M h c H+ M nadh c Nicotinamide adenine dinucleotide - reduced M nh4 c Ammonium

Kinetic Law

v476 = not speciﬁed (952)

6.477 Reaction R GLUPRT This is an irreversible reaction of three reactants forming three products.

Name glutamine phosphoribosyldiphosphate amidotransferase

Reaction equation M gln DASH L c + M h2o c + M prpp c −→ M glu DASH L c + M ppi c + M pram c (953)

Reactants

452 Produced by SBML2LATEX Table 871: Properties of each reactant. Id Name SBO M gln DASH L c L-Glutamine M h2o c H2O M prpp c 5-Phospho-alpha-D-ribose 1-diphosphate

Products

Table 872: Properties of each product. Id Name SBO M glu DASH L c L-Glutamate M ppi c Diphosphate M pram c 5-Phospho-beta-D-ribosylamine

Kinetic Law

v477 = not speciﬁed (954)

6.478 Reaction R GLUR This is a reversible reaction of one reactant forming one product.

Name glutamate racemase

Reaction equation M glu DASH D c )−−−−* M glu DASH L c (955)

Reactant

Table 873: Properties of each reactant. Id Name SBO M glu DASH D c D-Glutamate

Product

Produced by SBML2LATEX 453 Table 874: Properties of each product. Id Name SBO M glu DASH L c L-Glutamate

Kinetic Law

v478 = not speciﬁed (956)

6.479 Reaction R GLUSy This is an irreversible reaction of four reactants forming two products.

Name glutamate synthase (NADPH)

Reaction equation M akg c + M gln DASH L c + M h c + M nadph c −→ 2M glu DASH L c + M nadp c (957)

Reactants

Table 875: Properties of each reactant. Id Name SBO M akg c 2-Oxoglutarate M gln DASH L c L-Glutamine M h c H+ M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

Products

Table 876: Properties of each product. Id Name SBO M glu DASH L c L-Glutamate M nadp c Nicotinamide adenine dinucleotide phosphate

Kinetic Law

v479 = not speciﬁed (958)

454 Produced by SBML2LATEX 6.480 Reaction R GLUTRR This is an irreversible reaction of three reactants forming three products.

Name glutamyl-tRNA reductase

Reaction equation M glutrna c + M h c + M nadph c −→ M glu1sa c + M nadp c + M trnaglu c (959)

Reactants

Table 877: Properties of each reactant. Id Name SBO M glutrna c L-Glutamyl-tRNA(Glu) M h c H+ M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

Products

Table 878: Properties of each product. Id Name SBO M glu1sa c L-Glutamate 1-semialdehyde M nadp c Nicotinamide adenine dinucleotide phosphate M trnaglu c tRNA (Glu)

Kinetic Law

v480 = not speciﬁed (960)

6.481 Reaction R GLUt2r This is a reversible reaction of two reactants forming two products.

Name L-glutamate transport via proton symport, reversible

Reaction equation M glu DASH L e + M h e )−−−−* M glu DASH L c + M h c (961)

Reactants

Produced by SBML2LATEX 455 Table 879: Properties of each reactant. Id Name SBO M glu DASH L e L-Glutamate M h e H+

Products

Table 880: Properties of each product. Id Name SBO M glu DASH L c L-Glutamate M h c H+

Kinetic Law

v481 = not speciﬁed (962)

6.482 Reaction R GLXO1 This is an irreversible reaction of three reactants forming three products.

Name glyoxylate oxidase

Reaction equation M glx c + M h2o c + M nad c −→ 2M h c + M nadh c + M oxa c (963)

Reactants

Table 881: Properties of each reactant. Id Name SBO M glx c Glyoxylate M h2o c H2O M nad c Nicotinamide adenine dinucleotide

Products

456 Produced by SBML2LATEX Table 882: Properties of each product. Id Name SBO M h c H+ M nadh c Nicotinamide adenine dinucleotide - reduced M oxa c Oxalate

Kinetic Law

v482 = not speciﬁed (964)

6.483 Reaction R GLYBabc This is an irreversible reaction of three reactants forming four products.

Name Glycine betaine transport via ABC system

Reaction equation M atp c + M glyb e + M h2o c −→ M adp c + M glyb c + M h c + M pi c (965)

Reactants

Table 883: Properties of each reactant. Id Name SBO M atp c ATP M glyb e Glycine betaine M h2o c H2O

Products

Table 884: Properties of each product. Id Name SBO M adp c ADP M glyb c Glycine betaine M h c H+ M pi c Phosphate

Produced by SBML2LATEX 457 Kinetic Law

v483 = not speciﬁed (966)

6.484 Reaction R GLYC3Pabc This is an irreversible reaction of three reactants forming four products.

Name sn-Glycerol 3-phosphate transport via ABC system

Reaction equation M atp c + M glyc3p e + M h2o c −→ M adp c + M glyc3p c + M h c + M pi c (967)

Reactants

Table 885: Properties of each reactant. Id Name SBO M atp c ATP M glyc3p e Glycerol 3-phosphate M h2o c H2O

Products

Table 886: Properties of each product. Id Name SBO M adp c ADP M glyc3p c Glycerol 3-phosphate M h c H+ M pi c Phosphate

Kinetic Law

v484 = not speciﬁed (968)

6.485 Reaction R GLYCK This is an irreversible reaction of two reactants forming three products.

Name glycerate kinase

458 Produced by SBML2LATEX Reaction equation M atp c + M glyc DASH R c −→ M 3pg c + M adp c + M h c (969)

Reactants

Table 887: Properties of each reactant. Id Name SBO M atp c ATP M glyc DASH R c (R)-Glycerate

Products

Table 888: Properties of each product. Id Name SBO M 3pg c 3-Phospho-D-glycerate M adp c ADP M h c H+

Kinetic Law

v485 = not speciﬁed (970)

6.486 Reaction R GLYCL This is an irreversible reaction of three reactants forming four products.

Name Glycine Cleavage System

Reaction equation M gly c + M nad c + M thf c −→ M co2 c + M mlthf c + M nadh c + M nh4 c (971)

Reactants

Table 889: Properties of each reactant. Id Name SBO M gly c Glycine M nad c Nicotinamide adenine dinucleotide M thf c 5,6,7,8-Tetrahydrofolate

Produced by SBML2LATEX 459 Products

Table 890: Properties of each product. Id Name SBO M co2 c CO2 M mlthf c 5,10-Methylenetetrahydrofolate M nadh c Nicotinamide adenine dinucleotide - reduced M nh4 c Ammonium

Kinetic Law

v486 = not speciﬁed (972)

6.487 Reaction R GLYCTO1 This is an irreversible reaction of two reactants forming two products.

Name Glycolate oxidase

Reaction equation M glyclt c + M o2 c −→ M glx c + M h2o2 c (973)

Reactants

Table 891: Properties of each reactant. Id Name SBO M glyclt c Glycolate M o2 c O2

Products

Table 892: Properties of each product. Id Name SBO M glx c Glyoxylate M h2o2 c Hydrogen peroxide

460 Produced by SBML2LATEX Kinetic Law

v487 = not speciﬁed (974)

6.488 Reaction R GLYCTO2 This is an irreversible reaction of two reactants forming two products.

Name Glycolate oxidase

Reaction equation M glyclt c + M q8 c −→ M glx c + M q8h2 c (975)

Reactants

Table 893: Properties of each reactant. Id Name SBO M glyclt c Glycolate M q8 c Ubiquinone-8

Products

Table 894: Properties of each product. Id Name SBO M glx c Glyoxylate M q8h2 c Ubiquinol-8

Kinetic Law

v488 = not speciﬁed (976)

6.489 Reaction R GLYCTO3 This is an irreversible reaction of two reactants forming two products.

Name Glycolate oxidase

Reaction equation M glyclt c + M mqn8 c −→ M glx c + M mql8 c (977)

Produced by SBML2LATEX 461 Reactants

Table 895: Properties of each reactant. Id Name SBO M glyclt c Glycolate M mqn8 c Menaquinone 8

Products

Table 896: Properties of each product. Id Name SBO M glx c Glyoxylate M mql8 c Menaquinol 8

Kinetic Law

v489 = not speciﬁed (978)

6.490 Reaction R GLYCTO4 This is an irreversible reaction of two reactants forming two products.

Name Glycolate oxidase

Reaction equation M 2dmmq8 c + M glyclt c −→ M 2dmmql8 c + M glx c (979)

Reactants

Table 897: Properties of each reactant. Id Name SBO M 2dmmq8 c 2-Demethylmenaquinone 8 M glyclt c Glycolate

Products

462 Produced by SBML2LATEX Table 898: Properties of each product. Id Name SBO M 2dmmql8 c 2-Demethylmenaquinol 8 M glx c Glyoxylate

Kinetic Law

v490 = not speciﬁed (980)

6.491 Reaction R GLYCt This is a reversible reaction of one reactant forming one product.

Name glycerol transport via channel

Reaction equation M glyc c )−−−−* M glyc e (981)

Reactant

Table 899: Properties of each reactant. Id Name SBO M glyc c Glycerol

Product

Table 900: Properties of each product. Id Name SBO M glyc e Glycerol

Kinetic Law

v491 = not speciﬁed (982)

6.492 Reaction R GLYK This is an irreversible reaction of two reactants forming three products.

Name glycerol kinase

Produced by SBML2LATEX 463 Reaction equation M atp c + M glyc c −→ M adp c + M glyc3p c + M h c (983)

Reactants

Table 901: Properties of each reactant. Id Name SBO M atp c ATP M glyc c Glycerol

Products

Table 902: Properties of each product. Id Name SBO M adp c ADP M glyc3p c Glycerol 3-phosphate M h c H+

Kinetic Law

v492 = not speciﬁed (984)

6.493 Reaction R GLYt2r This is a reversible reaction of two reactants forming two products.

Name glycine reversible transport via proton symport

Reaction equation M gly e + M h e )−−−−* M gly c + M h c (985)

Reactants

Table 903: Properties of each reactant. Id Name SBO M gly e Glycine M h e H+

464 Produced by SBML2LATEX Products

Table 904: Properties of each product. Id Name SBO M gly c Glycine M h c H+

Kinetic Law

v493 = not speciﬁed (986)

6.494 Reaction R GMAND This is an irreversible reaction of one reactant forming two products.

Name GDP-D-mannose dehydratase

Reaction equation M gdpmann c −→ M gdpddman c + M h2o c (987)

Reactant

Table 905: Properties of each reactant. Id Name SBO M gdpmann c GDP-D-mannose

Products

Table 906: Properties of each product. Id Name SBO M gdpddman c GDP-4-dehydro-6-deoxy-D-mannose M h2o c H2O

Kinetic Law

v494 = not speciﬁed (988)

Produced by SBML2LATEX 465 6.495 Reaction R GMPS2 This is an irreversible reaction of four reactants forming ﬁve products.

Name GMP synthase

Reaction equation M atp c + M gln DASH L c + M h2o c + M xmp c −→ M amp c + M glu DASH L c + M gmp c + 2M h c + M ppi c (989)

Reactants

Table 907: Properties of each reactant. Id Name SBO M atp c ATP M gln DASH L c L-Glutamine M h2o c H2O M xmp c Xanthosine 5’-phosphate

Products

Table 908: Properties of each product. Id Name SBO M amp c AMP M glu DASH L c L-Glutamate M gmp c GMP M h c H+ M ppi c Diphosphate

Kinetic Law

v495 = not speciﬁed (990)

6.496 Reaction R GMT1

This is an irreversible reaction of two reactants forming two products.

Name gdp mannosyl phosphate transferase

466 Produced by SBML2LATEX Reaction equation M decd tb c + M gdpmann c −→ M decdman1p tb c + M gdp c (991)

Reactants

Table 909: Properties of each reactant. Id Name SBO M decd tb c (E,E,E,E,E,E,E,Z,Z) decaprenyl phosphate M gdpmann c GDP-D-mannose

Products

Table 910: Properties of each product. Id Name SBO M decdman1p tb c (E,E,E,E,E,E,E,Z,Z) decaprenyl mannose phosphate M gdp c GDP

Kinetic Law

v496 = not speciﬁed (992)

6.497 Reaction R GMT2 This is an irreversible reaction of two reactants forming three products.

Name gdp mannosyl phosphate transferase

Reaction equation 3M gdpmann c + M harab DASH D c −→ 3M gdp c + 3M h c + M mharab DASH D c (993)

Reactants

Table 911: Properties of each reactant. Id Name SBO M gdpmann c GDP-D-mannose M harab DASH D c hexa arabinofuranoside

Produced by SBML2LATEX 467 Products

Table 912: Properties of each product. Id Name SBO M gdp c GDP M h c H+ M mharab DASH D c mannose capped hexa arabinofuranoside

Kinetic Law

v497 = not speciﬁed (994)

6.498 Reaction R GND This is an irreversible reaction of two reactants forming three products.

Name phosphogluconate dehydrogenase

Reaction equation M 6pgc c + M nadp c −→ M co2 c + M nadph c + M ru5p DASH D c (995)

Reactants

Table 913: Properties of each reactant. Id Name SBO M 6pgc c 6-Phospho-D-gluconate M nadp c Nicotinamide adenine dinucleotide phosphate

Products

Table 914: Properties of each product. Id Name SBO M co2 c CO2 M nadph c Nicotinamide adenine dinucleotide phosphate - reduced M ru5p DASH D c D-Ribulose 5-phosphate

468 Produced by SBML2LATEX Kinetic Law

v498 = not speciﬁed (996)

6.499 Reaction R GPDDA2 This is an irreversible reaction of two reactants forming three products.

Name Glycerophosphodiester phosphodiesterase (Glycerophosphoethanolamine)

Reaction equation M g3pe c + M h2o c −→ M etha c + M glyc3p c + M h c (997)

Reactants

Table 915: Properties of each reactant. Id Name SBO M g3pe c sn-Glycero-3-phosphoethanolamine M h2o c H2O

Products

Table 916: Properties of each product. Id Name SBO M etha c Ethanolamine M glyc3p c Glycerol 3-phosphate M h c H+

Kinetic Law

v499 = not speciﬁed (998)

6.500 Reaction R GRTT This is an irreversible reaction of two reactants forming two products.

Name geranyltranstransferase

Reaction equation M grdp c + M ipdp c −→ M frdp c + M ppi c (999)

Produced by SBML2LATEX 469 Reactants

Table 917: Properties of each reactant. Id Name SBO M grdp c Geranyl diphosphate M ipdp c Isopentenyl diphosphate

Products

Table 918: Properties of each product. Id Name SBO M frdp c Farnesyl diphosphate M ppi c Diphosphate

Kinetic Law

v500 = not speciﬁed (1000)

6.501 Reaction R GSNK This is an irreversible reaction of two reactants forming three products.

Name guanosine kinase

Reaction equation M atp c + M gsn c −→ M adp c + M gmp c + M h c (1001)

Reactants

Table 919: Properties of each reactant. Id Name SBO M atp c ATP M gsn c Guanosine

Products

470 Produced by SBML2LATEX Table 920: Properties of each product. Id Name SBO M adp c ADP M gmp c GMP M h c H+

Kinetic Law

v501 = not speciﬁed (1002)

6.502 Reaction R GTHOr This is a reversible reaction of three reactants forming two products.

Name glutathione oxidoreductase

Reaction equation M gthox c + M h c + M nadph c )−−−−* 2M gthrd c + M nadp c (1003)

Reactants

Table 921: Properties of each reactant. Id Name SBO M gthox c Oxidized glutathione M h c H+ M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

Products

Table 922: Properties of each product. Id Name SBO M gthrd c Reduced glutathione M nadp c Nicotinamide adenine dinucleotide phosphate

Kinetic Law

v502 = not speciﬁed (1004)

Produced by SBML2LATEX 471 6.503 Reaction R GTHRDt2 This is an irreversible reaction of one reactant forming one product.

Name glutathione transport

Reaction equation M gthrd e −→ M gthrd c (1005)

Reactant

Table 923: Properties of each reactant. Id Name SBO M gthrd e Reduced glutathione

Product

Table 924: Properties of each product. Id Name SBO M gthrd c Reduced glutathione

Kinetic Law

v503 = not speciﬁed (1006)

6.504 Reaction R GTHS This is an irreversible reaction of three reactants forming four products.

Name glutathione synthetase

Reaction equation M atp c + M glucys c + M gly c −→ M adp c + M gthrd c + M h c + M pi c (1007)

Reactants

472 Produced by SBML2LATEX Table 925: Properties of each reactant. Id Name SBO M atp c ATP M glucys c gamma-L-Glutamyl-L-cysteine M gly c Glycine

Products

Table 926: Properties of each product. Id Name SBO M adp c ADP M gthrd c Reduced glutathione M h c H+ M pi c Phosphate

Kinetic Law

v504 = not speciﬁed (1008)

6.505 Reaction R GTMLT This is an irreversible reaction of two reactants forming two products.

Name g-glutamyltransferase

Reaction equation M ala DASH L c + M gthrd c −→ M cgly c + M gluala c (1009)

Reactants

Table 927: Properties of each reactant. Id Name SBO M ala DASH L c L-Alanine M gthrd c Reduced glutathione

Products

Produced by SBML2LATEX 473 Table 928: Properties of each product. Id Name SBO M cgly c Cys-Gly M gluala c 5-L-Glutamyl-L-alanine

Kinetic Law

v505 = not speciﬁed (1010)

6.506 Reaction R GTPCI This is an irreversible reaction of two reactants forming three products.

Name GTP cyclohydrolase I

Reaction equation M gtp c + M h2o c −→ M ahdt c + M for c + M h c (1011)

Reactants

Table 929: Properties of each reactant. Id Name SBO M gtp c GTP M h2o c H2O

Products

Table 930: Properties of each product. Id Name SBO M ahdt c 2-Amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)dihydropteridine triphosphate M for c Formate M h c H+

Kinetic Law

v506 = not speciﬁed (1012)

474 Produced by SBML2LATEX 6.507 Reaction R GTPCII This is an irreversible reaction of two reactants forming four products.

Name GTP cyclohydrolase II

Reaction equation M gtp c + 3M h2o c −→ M 25dhpp c + M for c + 2M h c + M ppi c (1013)

Reactants

Table 931: Properties of each reactant. Id Name SBO M gtp c GTP M h2o c H2O

Products

Table 932: Properties of each product. Id Name SBO M 25dhpp c 2,5-Diamino-6-hydroxy-4-(5’-phosphoribosylamino)-pyrimidine M for c Formate M h c H+ M ppi c Diphosphate

Kinetic Law

v507 = not speciﬁed (1014)

6.508 Reaction R GTPCII2 This is an irreversible reaction of two reactants forming four products.

Name GTP cyclohydrolase II (25drapp)

Reaction equation M gtp c + 3M h2o c −→ M 25drapp c + M for c + 2M h c + M ppi c (1015)

Reactants

Produced by SBML2LATEX 475 Table 933: Properties of each reactant. Id Name SBO M gtp c GTP M h2o c H2O

Products

Table 934: Properties of each product. Id Name SBO M 25drapp c 2,5-Diamino-6-(ribosylamino)-4-(3H)-pyrimidinone 5’-phosphate M for c Formate M h c H+ M ppi c Diphosphate

Kinetic Law

v508 = not speciﬁed (1016)

6.509 Reaction R GTPDPK This is an irreversible reaction of two reactants forming three products.

Name GTP diphosphokinase

Reaction equation M atp c + M gtp c −→ M amp c + M gdptp c + M h c (1017)

Reactants

Table 935: Properties of each reactant. Id Name SBO M atp c ATP M gtp c GTP

Products

476 Produced by SBML2LATEX Table 936: Properties of each product. Id Name SBO M amp c AMP M gdptp c Guanosine 3’-diphosphate 5’-triphosphate M h c H+

Kinetic Law

v509 = not speciﬁed (1018)

6.510 Reaction R GTPH1 This is an irreversible reaction of two reactants forming three products.

Name GTP diphosphohydrolase

Reaction equation M gtp c + 2M h2o c −→ M gmp c + 2M h c + 2M pi c (1019)

Reactants

Table 937: Properties of each reactant. Id Name SBO M gtp c GTP M h2o c H2O

Products

Table 938: Properties of each product. Id Name SBO M gmp c GMP M h c H+ M pi c Phosphate

Kinetic Law

v510 = not speciﬁed (1020)

Produced by SBML2LATEX 477 6.511 Reaction R GUACYC This is an irreversible reaction of one reactant forming two products.

Name guanylate cyclase

Reaction equation M gtp c −→ M 35cgmp c + M ppi c (1021)

Reactant

Table 939: Properties of each reactant. Id Name SBO M gtp c GTP

Products

Table 940: Properties of each product. Id Name SBO M 35cgmp c 3’,5’-Cyclic GMP M ppi c Diphosphate

Kinetic Law

v511 = not speciﬁed (1022)

6.512 Reaction R GUAD This is an irreversible reaction of three reactants forming two products.

Name guanine deaminase

Reaction equation M gua c + M h2o c + M h c −→ M nh4 c + M xan c (1023)

Reactants

478 Produced by SBML2LATEX Table 941: Properties of each reactant. Id Name SBO M gua c Guanine M h2o c H2O M h c H+

Products

Table 942: Properties of each product. Id Name SBO M nh4 c Ammonium M xan c Xanthine

Kinetic Law

v512 = not speciﬁed (1024)

6.513 Reaction R GUAPRT This is an irreversible reaction of two reactants forming two products.

Name guanine phosphoribosyltransferase

Reaction equation M gua c + M prpp c −→ M gmp c + M ppi c (1025)

Reactants

Table 943: Properties of each reactant. Id Name SBO M gua c Guanine M prpp c 5-Phospho-alpha-D-ribose 1-diphosphate

Products

Produced by SBML2LATEX 479 Table 944: Properties of each product. Id Name SBO M gmp c GMP M ppi c Diphosphate

Kinetic Law

v513 = not speciﬁed (1026)

6.514 Reaction R H2CO3D This is a reversible reaction of two reactants forming one product.

Name carboxylic acid dissociation

Reaction equation M co2 c + M h2o c )−−−−* M h2co3 c (1027)

Reactants

Table 945: Properties of each reactant. Id Name SBO M co2 c CO2 M h2o c H2O

Product

Table 946: Properties of each product. Id Name SBO M h2co3 c carbonic acid

Kinetic Law

v514 = not speciﬁed (1028)

6.515 Reaction R H2CO3TP This is a reversible reaction of one reactant forming one product.

480 Produced by SBML2LATEX Name H2CO3 transport

Reaction equation M h2co3 e )−−−−* M h2co3 c (1029)

Reactant

Table 947: Properties of each reactant. Id Name SBO M h2co3 e carbonic acid

Product

Table 948: Properties of each product. Id Name SBO M h2co3 c carbonic acid

Kinetic Law

v515 = not speciﬁed (1030)

6.516 Reaction R H2Ot This is a reversible reaction of one reactant forming one product.

Name H2O transport via diffusion

Reaction equation M h2o e )−−−−* M h2o c (1031)

Reactant

Table 949: Properties of each reactant. Id Name SBO M h2o e H2O

Produced by SBML2LATEX 481 Product

Table 950: Properties of each product. Id Name SBO M h2o c H2O

Kinetic Law

v516 = not speciﬁed (1032)

6.517 Reaction R H2St1 This is an irreversible reaction of one reactant forming one product.

Name h2s transport

Reaction equation M h2s c −→ M h2s e (1033)

Reactant

Table 951: Properties of each reactant. Id Name SBO M h2s c Hydrogen sulﬁde

Product

Table 952: Properties of each product. Id Name SBO M h2s e Hydrogen sulﬁde

Kinetic Law

v517 = not speciﬁed (1034)

6.518 Reaction R H2td This is a reversible reaction of one reactant forming one product.

482 Produced by SBML2LATEX Name hydrogen transport

Reaction equation M h2 c )−−−−* M h2 e (1035)

Reactant

Table 953: Properties of each reactant. Id Name SBO M h2 c H2

Product

Table 954: Properties of each product. Id Name SBO M h2 e H2

Kinetic Law

v518 = not speciﬁed (1036)

6.519 Reaction R HAS This is an irreversible reaction of two reactants forming two products.

Name hexa-arabinofuranoside synthesis

Reaction equation M arab DASH D c + 5M decda tb c −→ 5M decd tb c + M harab DASH D c (1037)

Reactants

Table 955: Properties of each reactant. Id Name SBO M arab DASH D c D-Arabinose M decda tb c decaprenylphosphoryl-beta-D-arabinofuranose

Produced by SBML2LATEX 483 Products

Table 956: Properties of each product. Id Name SBO M decd tb c (E,E,E,E,E,E,E,Z,Z) decaprenyl phosphate M harab DASH D c hexa arabinofuranoside

Kinetic Law

v519 = not speciﬁed (1038)

6.520 Reaction R HCO3E This is a reversible reaction of two reactants forming two products.

Name HCO3 equilibration reaction

Reaction equation M co2 c + M h2o c )−−−−* M h c + M hco3 c (1039)

Reactants

Table 957: Properties of each reactant. Id Name SBO M co2 c CO2 M h2o c H2O

Products

Table 958: Properties of each product. Id Name SBO M h c H+ M hco3 c Bicarbonate

Kinetic Law

v520 = not speciﬁed (1040)

484 Produced by SBML2LATEX 6.521 Reaction R HCYSMT This is an irreversible reaction of two reactants forming three products.

Name homocysteine S-methyltransferase

Reaction equation M amet c + M hcys DASH L c −→ M ahcys c + M h c + M met DASH L c (1041)

Reactants

Table 959: Properties of each reactant. Id Name SBO M amet c S-Adenosyl-L-methionine M hcys DASH L c L-Homocysteine

Products

Table 960: Properties of each product. Id Name SBO M ahcys c S-Adenosyl-L-homocysteine M h c H+ M met DASH L c L-Methionine

Kinetic Law

v521 = not speciﬁed (1042)

6.522 Reaction R HDCAt2 This is an irreversible reaction of two reactants forming two products.

Name Hexadecanoate transport via proton symport

Reaction equation M h e + M hdca e −→ M h c + M hdca c (1043)

Reactants

Produced by SBML2LATEX 485 Table 961: Properties of each reactant. Id Name SBO M h e H+ M hdca e Hexadecanoate (n-C16:0)

Products

Table 962: Properties of each product. Id Name SBO M h c H+ M hdca c Hexadecanoate (n-C16:0)

Kinetic Law

v522 = not speciﬁed (1044)

6.523 Reaction R HEX1 This is an irreversible reaction of two reactants forming three products.

Name hexokinase (D-glucose:ATP)

Reaction equation M atp c + M glc DASH D c −→ M adp c + M g6p c + M h c (1045)

Reactants

Table 963: Properties of each reactant. Id Name SBO M atp c ATP M glc DASH D c D-Glucose

Products

Table 964: Properties of each product. Id Name SBO M adp c ADP

486 Produced by SBML2LATEX Id Name SBO M g6p c D-Glucose 6-phosphate M h c H+

Kinetic Law

v523 = not speciﬁed (1046)

6.524 Reaction R HISTD This is an irreversible reaction of three reactants forming three products.

Name histidinol dehydrogenase

Reaction equation M h2o c + M histd c + 2M nad c −→ 3M h c + M his DASH L c + 2M nadh c (1047)

Reactants

Table 965: Properties of each reactant. Id Name SBO M h2o c H2O M histd c L-Histidinol M nad c Nicotinamide adenine dinucleotide

Products

Table 966: Properties of each product. Id Name SBO M h c H+ M his DASH L c L-Histidine M nadh c Nicotinamide adenine dinucleotide - reduced

Kinetic Law

v524 = not speciﬁed (1048)

6.525 Reaction R HISTP This is an irreversible reaction of two reactants forming two products.

Produced by SBML2LATEX 487 Name histidinol-phosphatase

Reaction equation M h2o c + M hisp c −→ M histd c + M pi c (1049)

Reactants

Table 967: Properties of each reactant. Id Name SBO M h2o c H2O M hisp c L-Histidinol phosphate

Products

Table 968: Properties of each product. Id Name SBO M histd c L-Histidinol M pi c Phosphate

Kinetic Law

v525 = not speciﬁed (1050)

6.526 Reaction R HISt2r This is a reversible reaction of two reactants forming two products.

Name L-histidine reversible transport via proton symport

Reaction equation M h e + M his DASH L e )−−−−* M h c + M his DASH L c (1051)

Reactants

Table 969: Properties of each reactant. Id Name SBO M h e H+ M his DASH L e L-Histidine

488 Produced by SBML2LATEX Products

Table 970: Properties of each product. Id Name SBO M h c H+ M his DASH L c L-Histidine

Kinetic Law

v526 = not speciﬁed (1052)

6.527 Reaction R HMBS This is an irreversible reaction of two reactants forming two products.

Name hydroxymethylbilane synthase

Reaction equation M h2o c + 4M ppbng c −→ M hmbil c + 4M nh4 c (1053)

Reactants

Table 971: Properties of each reactant. Id Name SBO M h2o c H2O M ppbng c Porphobilinogen

Products

Table 972: Properties of each product. Id Name SBO M hmbil c Hydroxymethylbilane M nh4 c Ammonium

Kinetic Law

v527 = not speciﬁed (1054)

Produced by SBML2LATEX 489 6.528 Reaction R HMPK1 This is an irreversible reaction of two reactants forming three products.

Name hydroxymethylpyrimidine kinase (ATP)

Reaction equation M 4ahmmp c + M atp c −→ M 4ampm c + M adp c + M h c (1055)

Reactants

Table 973: Properties of each reactant. Id Name SBO M 4ahmmp c 4-Amino-5-hydroxymethyl-2-methylpyrimidine M atp c ATP

Products

Table 974: Properties of each product. Id Name SBO M 4ampm c 4-Amino-2-methyl-5-phosphomethylpyrimidine M adp c ADP M h c H+

Kinetic Law

v528 = not speciﬁed (1056)

6.529 Reaction R HMPK2 This is an irreversible reaction of two reactants forming three products.

Name hydroxymethylpyrimidine kinase (CTP)

Reaction equation M 4ahmmp c + M ctp c −→ M 4ampm c + M cdp c + M h c (1057)

Reactants

490 Produced by SBML2LATEX Table 975: Properties of each reactant. Id Name SBO M 4ahmmp c 4-Amino-5-hydroxymethyl-2-methylpyrimidine M ctp c CTP

Products

Table 976: Properties of each product. Id Name SBO M 4ampm c 4-Amino-2-methyl-5-phosphomethylpyrimidine M cdp c CDP M h c H+

Kinetic Law

v529 = not speciﬁed (1058)

6.530 Reaction R HMPK3 This is an irreversible reaction of two reactants forming three products.

Name hydroxymethylpyrimidine kinase (UTP)

Reaction equation M 4ahmmp c + M utp c −→ M 4ampm c + M h c + M udp c (1059)

Reactants

Table 977: Properties of each reactant. Id Name SBO M 4ahmmp c 4-Amino-5-hydroxymethyl-2-methylpyrimidine M utp c UTP

Products

Produced by SBML2LATEX 491 Table 978: Properties of each product. Id Name SBO M 4ampm c 4-Amino-2-methyl-5-phosphomethylpyrimidine M h c H+ M udp c UDP

Kinetic Law

v530 = not speciﬁed (1060)

6.531 Reaction R HMPK4 This is an irreversible reaction of two reactants forming three products.

Name hydroxymethylpyrimidine kinase (GTP)

Reaction equation M 4ahmmp c + M gtp c −→ M 4ampm c + M gdp c + M h c (1061)

Reactants

Table 979: Properties of each reactant. Id Name SBO M 4ahmmp c 4-Amino-5-hydroxymethyl-2-methylpyrimidine M gtp c GTP

Products

Table 980: Properties of each product. Id Name SBO M 4ampm c 4-Amino-2-methyl-5-phosphomethylpyrimidine M gdp c GDP M h c H+

Kinetic Law

v531 = not speciﬁed (1062)

492 Produced by SBML2LATEX 6.532 Reaction R HOPNTAL This is an irreversible reaction of one reactant forming two products.

Name 4-hydroxy-2-oxopentanoate aldolase

Reaction equation M 4h2opntn c −→ M acald c + M pyr c (1063)

Reactant

Table 981: Properties of each reactant. Id Name SBO M 4h2opntn c 4-Hydroxy-2-oxopentanoate

Products

Table 982: Properties of each product. Id Name SBO M acald c Acetaldehyde M pyr c Pyruvate

Kinetic Law

v532 = not speciﬁed (1064)

6.533 Reaction R HPPK This is an irreversible reaction of two reactants forming three products.

Name 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase

Reaction equation M 2ahhmp c + M atp c −→ M 2ahhmd c + M amp c + M h c (1065)

Reactants

Produced by SBML2LATEX 493 Table 983: Properties of each reactant. Id Name SBO M 2ahhmp c 2-Amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine M atp c ATP

Products

Table 984: Properties of each product. Id Name SBO M 2ahhmd c 2-Amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate M amp c AMP M h c H+

Kinetic Law

v533 = not speciﬁed (1066)

6.534 Reaction R HPPK2 This is an irreversible reaction of two reactants forming three products.

Name 6-hydroxymethyl-dihydropterin pyrophosphokinase

Reaction equation M 6hmhpt c + M atp c −→ M 6hmhptpp c + M amp c + M h c (1067)

Reactants

Table 985: Properties of each reactant. Id Name SBO M 6hmhpt c 6-hydroxymethyl dihydropterin M atp c ATP

Products

494 Produced by SBML2LATEX Table 986: Properties of each product. Id Name SBO M 6hmhptpp c 6-hydroxymethyl-dihydropterin pyrophosphate M amp c AMP M h c H+

Kinetic Law

v534 = not speciﬁed (1068)

6.535 Reaction R HSDx This is a reversible reaction of two reactants forming three products.

Name homoserine dehydrogenase (NADH)

Reaction equation M hom DASH L c + M nad c )−−−−* M aspsa c + M h c + M nadh c (1069)

Reactants

Table 987: Properties of each reactant. Id Name SBO M hom DASH L c L-Homoserine M nad c Nicotinamide adenine dinucleotide

Products

Table 988: Properties of each product. Id Name SBO M aspsa c L-Aspartate 4-semialdehyde M h c H+ M nadh c Nicotinamide adenine dinucleotide - reduced

Kinetic Law

v535 = not speciﬁed (1070)

Produced by SBML2LATEX 495 6.536 Reaction R HSDy This is a reversible reaction of two reactants forming three products.

Name homoserine dehydrogenase (NADPH)

Reaction equation M hom DASH L c + M nadp c )−−−−* M aspsa c + M h c + M nadph c (1071)

Reactants

Table 989: Properties of each reactant. Id Name SBO M hom DASH L c L-Homoserine M nadp c Nicotinamide adenine dinucleotide phosphate

Products

Table 990: Properties of each product. Id Name SBO M aspsa c L-Aspartate 4-semialdehyde M h c H+ M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

Kinetic Law

v536 = not speciﬁed (1072)

6.537 Reaction R HSERTA This is a reversible reaction of two reactants forming two products.

Name homoserine O-trans-acetylase

Reaction equation M accoa c + M hom DASH L c )−−−−* M achms c + M coa c (1073)

Reactants

496 Produced by SBML2LATEX Table 991: Properties of each reactant. Id Name SBO M accoa c Acetyl-CoA M hom DASH L c L-Homoserine

Products

Table 992: Properties of each product. Id Name SBO M achms c O-Acetyl-L-homoserine M coa c Coenzyme A

Kinetic Law

v537 = not speciﬁed (1074)

6.538 Reaction R HSK This is an irreversible reaction of two reactants forming three products.

Name homoserine kinase

Reaction equation M atp c + M hom DASH L c −→ M adp c + M h c + M phom c (1075)

Reactants

Table 993: Properties of each reactant. Id Name SBO M atp c ATP M hom DASH L c L-Homoserine

Products

Table 994: Properties of each product. Id Name SBO M adp c ADP

Produced by SBML2LATEX 497 Id Name SBO M h c H+ M phom c O-Phospho-L-homoserine

Kinetic Law

v538 = not speciﬁed (1076)

6.539 Reaction R HSST This is an irreversible reaction of two reactants forming two products.

Name homoserine O-succinyltransferase

Reaction equation M hom DASH L c + M succoa c −→ M coa c + M suchms c (1077)

Reactants

Table 995: Properties of each reactant. Id Name SBO M hom DASH L c L-Homoserine M succoa c Succinyl-CoA

Products

Table 996: Properties of each product. Id Name SBO M coa c Coenzyme A M suchms c O-Succinyl-L-homoserine

Kinetic Law

v539 = not speciﬁed (1078)

6.540 Reaction R HSTPT This is an irreversible reaction of two reactants forming two products. Name histidinol-phosphate transaminase

498 Produced by SBML2LATEX Reaction equation M glu DASH L c + M imacp c −→ M akg c + M hisp c (1079)

Reactants

Table 997: Properties of each reactant. Id Name SBO M glu DASH L c L-Glutamate M imacp c 3-(Imidazol-4-yl)-2-oxopropyl phosphate

Products

Table 998: Properties of each product. Id Name SBO M akg c 2-Oxoglutarate M hisp c L-Histidinol phosphate

Kinetic Law

v540 = not speciﬁed (1080)

6.541 Reaction R HXPRT This is an irreversible reaction of two reactants forming two products.

Name hypoxanthine phosphoribosyltransferase (Hypoxanthine)

Reaction equation M hxan c + M prpp c −→ M imp c + M ppi c (1081)

Reactants

Table 999: Properties of each reactant. Id Name SBO M hxan c Hypoxanthine M prpp c 5-Phospho-alpha-D-ribose 1-diphosphate

Produced by SBML2LATEX 499 Products

Table 1000: Properties of each product. Id Name SBO M imp c IMP M ppi c Diphosphate

Kinetic Law

v541 = not speciﬁed (1082)

6.542 Reaction R IACGAMS This is an irreversible reaction of two reactants forming two products.

Name 1D-myo-inositol 2-Acetamido-2-deoxy-D-glucopyranoside synthesis

Reaction equation M acgam c + M mi1p DASH D c −→ M iacgam c + M pi c (1083)

Reactants

Table 1001: Properties of each reactant. Id Name SBO M acgam c N-Acetyl-D-glucosamine M mi1p DASH D c 1D-myo-Inositol 1-phosphate

Products

Table 1002: Properties of each product. Id Name SBO M iacgam c 1D-myo-inositol 2-Acetamido-2-deoxy-D-glucopyranoside M pi c Phosphate

Kinetic Law

v542 = not speciﬁed (1084)

500 Produced by SBML2LATEX 6.543 Reaction R ICDHy This is an irreversible reaction of two reactants forming three products.

Name isocitrate dehydrogenase (NADP)

Reaction equation M icit c + M nadp c −→ M akg c + M co2 c + M nadph c (1085)

Reactants

Table 1003: Properties of each reactant. Id Name SBO M icit c Isocitrate M nadp c Nicotinamide adenine dinucleotide phosphate

Products

Table 1004: Properties of each product. Id Name SBO M akg c 2-Oxoglutarate M co2 c CO2 M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

Kinetic Law

v543 = not speciﬁed (1086)

6.544 Reaction R ICHORSi This is an irreversible reaction of one reactant forming one product.

Name Isochorismate Synthase

Reaction equation M chor c −→ M ichor c (1087)

Reactant

Produced by SBML2LATEX 501 Table 1005: Properties of each reactant. Id Name SBO M chor c chorismate

Product

Table 1006: Properties of each product. Id Name SBO M ichor c Isochorismate

Kinetic Law

v544 = not speciﬁed (1088)

6.545 Reaction R ICL This is an irreversible reaction of one reactant forming two products.

Name Isocitrate lyase

Reaction equation M icit c −→ M glx c + M succ c (1089)

Reactant

Table 1007: Properties of each reactant. Id Name SBO M icit c Isocitrate

Products

Table 1008: Properties of each product. Id Name SBO M glx c Glyoxylate M succ c Succinate

502 Produced by SBML2LATEX Kinetic Law

v545 = not speciﬁed (1090)

6.546 Reaction R ID3ACALDt This is a reversible reaction of one reactant forming one product.

Name Indoleacetaldehyde transport (extracellular)

Reaction equation M id3acald c )−−−−* M id3acald e (1091)

Reactant

Table 1009: Properties of each reactant. Id Name SBO M id3acald c Indole-3-acetaldehyde

Product

Table 1010: Properties of each product. Id Name SBO M id3acald e Indole-3-acetaldehyde

Kinetic Law

v546 = not speciﬁed (1092)

6.547 Reaction R IG3PS This is an irreversible reaction of two reactants forming four products.

Name Imidazole-glycerol-3-phosphate synthase

Reaction equation

M gln DASH L c + M prlp c −→ M aicar c + M eig3p c + M glu DASH L c + M h c (1093)

Produced by SBML2LATEX 503 Reactants

504 Produced by SBML2LATEX Table 1011: Properties of each reactant. Id Name SBO M gln DASH L c L-Glutamine M prlp c 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]-1-(5-phosphoribosyl)imidazole-4-carboxamide

Products

Table 1012: Properties of each product. Id Name SBO M aicar c 5-Amino-1-(5-Phospho-D-ribosyl)imidazole-4-carboxamide M eig3p c D-erythro-1-(Imidazol-4-yl)glycerol 3-phosphate M glu DASH L c L-Glutamate M h c H+

Kinetic Law

v547 = not speciﬁed (1094)

6.548 Reaction R IGAMD This is an irreversible reaction of two reactants forming two products.

Name 1D-myo-inositol 2-Acetamido-2-deoxy-D-glucopyranoside deacetylase

Reaction equation M h2o c + M iacgam c −→ M ac c + M igam c (1095)

Reactants

Table 1013: Properties of each reactant. Id Name SBO M h2o c H2O M iacgam c 1D-myo-inositol 2-Acetamido-2-deoxy-D-glucopyranoside

Products

Produced by SBML2LATEX 505 Table 1014: Properties of each product. Id Name SBO M ac c Acetate M igam c 1D-myo-inositol 2-deoxy-D-glucopyranoside

Kinetic Law

v548 = not speciﬁed (1096)

6.549 Reaction R IGPDH This is an irreversible reaction of one reactant forming two products.

Name imidazoleglycerol-phosphate dehydratase

Reaction equation M eig3p c −→ M h2o c + M imacp c (1097)

Reactant

Table 1015: Properties of each reactant. Id Name SBO M eig3p c D-erythro-1-(Imidazol-4-yl)glycerol 3-phosphate

Products

Table 1016: Properties of each product. Id Name SBO M h2o c H2O M imacp c 3-(Imidazol-4-yl)-2-oxopropyl phosphate

Kinetic Law

v549 = not speciﬁed (1098)

6.550 Reaction R IGPS This is an irreversible reaction of two reactants forming three products.

506 Produced by SBML2LATEX Name indole-3-glycerol-phosphate synthase

Reaction equation M 2cpr5p c + M h c −→ M 3ig3p c + M co2 c + M h2o c (1099)

Reactants

Table 1017: Properties of each reactant. Id Name SBO M 2cpr5p c 1-(2-Carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate M h c H+

Products

Table 1018: Properties of each product. Id Name SBO M 3ig3p c C’-(3-Indolyl)-glycerol 3-phosphate M co2 c CO2 M h2o c H2O

Kinetic Law

v550 = not speciﬁed (1100)

6.551 Reaction R ILETA This is a reversible reaction of two reactants forming two products.

Name isoleucine transaminase

Reaction equation M akg c + M ile DASH L c )−−−−* M 3mop c + M glu DASH L c (1101)

Reactants

Produced by SBML2LATEX 507 Table 1019: Properties of each reactant. Id Name SBO M akg c 2-Oxoglutarate M ile DASH L c L-Isoleucine

Products

Table 1020: Properties of each product. Id Name SBO M 3mop c (S)-3-Methyl-2-oxopentanoate M glu DASH L c L-Glutamate

Kinetic Law

v551 = not speciﬁed (1102)

6.552 Reaction R ILEt2r This is a reversible reaction of two reactants forming two products.

Name L-isoleucine reversible transport via proton symport

Reaction equation M h e + M ile DASH L e )−−−−* M h c + M ile DASH L c (1103)

Reactants

Table 1021: Properties of each reactant. Id Name SBO M h e H+ M ile DASH L e L-Isoleucine

Products

Table 1022: Properties of each product. Id Name SBO M h c H+

508 Produced by SBML2LATEX Id Name SBO M ile DASH L c L-Isoleucine

Kinetic Law

v552 = not speciﬁed (1104)

6.553 Reaction R IMPC This is a reversible reaction of two reactants forming one product.

Name IMP cyclohydrolase

Reaction equation M h2o c + M imp c )−−−−* M fprica c (1105)

Reactants

Table 1023: Properties of each reactant. Id Name SBO M h2o c H2O M imp c IMP

Product

Table 1024: Properties of each product. Id Name SBO M fprica c 5-Formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

Kinetic Law

v553 = not speciﬁed (1106)

6.554 Reaction R IMPD This is an irreversible reaction of three reactants forming three products.

Name IMP dehydrogenase

Produced by SBML2LATEX 509 Reaction equation M h2o c + M imp c + M nad c −→ M h c + M nadh c + M xmp c (1107)

Reactants

Table 1025: Properties of each reactant. Id Name SBO M h2o c H2O M imp c IMP M nad c Nicotinamide adenine dinucleotide

Products

Table 1026: Properties of each product. Id Name SBO M h c H+ M nadh c Nicotinamide adenine dinucleotide - reduced M xmp c Xanthosine 5’-phosphate

Kinetic Law

v554 = not speciﬁed (1108)

6.555 Reaction R INDPYRD This is a reversible reaction of two reactants forming two products.

Name Indole-3-pyruvate decarboxylase

Reaction equation M h c + M indpyr c )−−−−* M co2 c + M id3acald c (1109)

Reactants

Table 1027: Properties of each reactant. Id Name SBO M h c H+ M indpyr c Indolepyruvate

510 Produced by SBML2LATEX Products

Table 1028: Properties of each product. Id Name SBO M co2 c CO2 M id3acald c Indole-3-acetaldehyde

Kinetic Law

v555 = not speciﬁed (1110)

6.556 Reaction R INSH This is an irreversible reaction of two reactants forming two products.

Name Inosine hydrolase

Reaction equation M h2o c + M ins c −→ M hxan c + M rib DASH D c (1111)

Reactants

Table 1029: Properties of each reactant. Id Name SBO M h2o c H2O M ins c Inosine

Products

Table 1030: Properties of each product. Id Name SBO M hxan c Hypoxanthine M rib DASH D c D-Ribose

Kinetic Law

v556 = not speciﬁed (1112)

Produced by SBML2LATEX 511 6.557 Reaction R INSK This is an irreversible reaction of two reactants forming three products.

Name insosine kinase

Reaction equation M atp c + M ins c −→ M adp c + M h c + M imp c (1113)

Reactants

Table 1031: Properties of each reactant. Id Name SBO M atp c ATP M ins c Inosine

Products

Table 1032: Properties of each product. Id Name SBO M adp c ADP M h c H+ M imp c IMP

Kinetic Law

v557 = not speciﬁed (1114)

6.558 Reaction R IPDDI This is a reversible reaction of one reactant forming one product.

Name isopentenyl-diphosphate D-isomerase

Reaction equation M ipdp c )−−−−* M dmpp c (1115)

Reactant

512 Produced by SBML2LATEX Table 1033: Properties of each reactant. Id Name SBO M ipdp c Isopentenyl diphosphate

Product

Table 1034: Properties of each product. Id Name SBO M dmpp c Dimethylallyl diphosphate

Kinetic Law

v558 = not speciﬁed (1116)

6.559 Reaction R IPDPS This is an irreversible reaction of three reactants forming three products.

Name 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase (ipdp)

Reaction equation M h2mb4p c + M h c + M nadh c −→ M h2o c + M ipdp c + M nad c (1117)

Reactants

Table 1035: Properties of each reactant. Id Name SBO M h2mb4p c 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate M h c H+ M nadh c Nicotinamide adenine dinucleotide - reduced

Products

Table 1036: Properties of each product. Id Name SBO M h2o c H2O M ipdp c Isopentenyl diphosphate

Produced by SBML2LATEX 513 Id Name SBO M nad c Nicotinamide adenine dinucleotide

Kinetic Law

v559 = not speciﬁed (1118)

6.560 Reaction R IPMD This is an irreversible reaction of two reactants forming three products.

Name 3-isopropylmalate dehydrogenase

Reaction equation M 3c2hmp c + M nad c −→ M 3c4mop c + M h c + M nadh c (1119)

Reactants

Table 1037: Properties of each reactant. Id Name SBO M 3c2hmp c 3-Carboxy-2-hydroxy-4-methylpentanoate M nad c Nicotinamide adenine dinucleotide

Products

Table 1038: Properties of each product. Id Name SBO M 3c4mop c 3-Carboxy-4-methyl-2-oxopentanoate M h c H+ M nadh c Nicotinamide adenine dinucleotide - reduced

Kinetic Law

v560 = not speciﬁed (1120)

6.561 Reaction R IPPMIa This is a reversible reaction of one reactant forming two products. Name 3-isopropylmalate dehydratase

514 Produced by SBML2LATEX Reaction equation M 3c2hmp c )−−−−* M 2ippm c + M h2o c (1121)

Reactant

Table 1039: Properties of each reactant. Id Name SBO M 3c2hmp c 3-Carboxy-2-hydroxy-4-methylpentanoate

Products

Table 1040: Properties of each product. Id Name SBO M 2ippm c 2-Isopropylmaleate M h2o c H2O

Kinetic Law

v561 = not speciﬁed (1122)

6.562 Reaction R IPPMIb This is a reversible reaction of two reactants forming one product.

Name 2-isopropylmalate hydratase

Reaction equation M 2ippm c + M h2o c )−−−−* M 3c3hmp c (1123)

Reactants

Table 1041: Properties of each reactant. Id Name SBO M 2ippm c 2-Isopropylmaleate M h2o c H2O

Produced by SBML2LATEX 515 Product

Table 1042: Properties of each product. Id Name SBO M 3c3hmp c 3-Carboxy-3-hydroxy-4-methylpentanoate

Kinetic Law

v562 = not speciﬁed (1124)

6.563 Reaction R IPPS This is an irreversible reaction of three reactants forming three products.

Name 2-isopropylmalate synthase

Reaction equation M 3mob c + M accoa c + M h2o c −→ M 3c3hmp c + M coa c + M h c (1125)

Reactants

Table 1043: Properties of each reactant. Id Name SBO M 3mob c 3-Methyl-2-oxobutanoate M accoa c Acetyl-CoA M h2o c H2O

Products

Table 1044: Properties of each product. Id Name SBO M 3c3hmp c 3-Carboxy-3-hydroxy-4-methylpentanoate M coa c Coenzyme A M h c H+

Kinetic Law

v563 = not speciﬁed (1126)

516 Produced by SBML2LATEX 6.564 Reaction R KARA1i This is an irreversible reaction of three reactants forming two products.

Name acetohydroxy acid isomeroreductase

Reaction equation M alac DASH S c + M h c + M nadph c −→ M 23dhmb c + M nadp c (1127)

Reactants

Table 1045: Properties of each reactant. Id Name SBO M alac DASH S c (S)-2-Acetolactate M h c H+ M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

Products

Table 1046: Properties of each product. Id Name SBO M 23dhmb c (R)-2,3-Dihydroxy-3-methylbutanoate M nadp c Nicotinamide adenine dinucleotide phosphate

Kinetic Law

v564 = not speciﬁed (1128)

6.565 Reaction R KARA2i This is an irreversible reaction of three reactants forming two products.

Name ketol-acid reductoisomerase (2-Aceto-2-hydroxybutanoate)

Reaction equation M 2ahbut c + M h c + M nadph c −→ M 23dhmp c + M nadp c (1129)

Reactants

Produced by SBML2LATEX 517 Table 1047: Properties of each reactant. Id Name SBO M 2ahbut c (S)-2-Aceto-2-hydroxybutanoate M h c H+ M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

Products

Table 1048: Properties of each product. Id Name SBO M 23dhmp c (R)-2,3-Dihydroxy-3-methylpentanoate M nadp c Nicotinamide adenine dinucleotide phosphate

Kinetic Law

v565 = not speciﬁed (1130)

6.566 Reaction R Kabc This is an irreversible reaction of three reactants forming four products.

Name Potassium ABC transporter

Reaction equation M atp c + M h2o c + M k e −→ M adp c + M h c + M k c + M pi c (1131)

Reactants

Table 1049: Properties of each reactant. Id Name SBO M atp c ATP M h2o c H2O M k e potassium

Products

518 Produced by SBML2LATEX Table 1050: Properties of each product. Id Name SBO M adp c ADP M h c H+ M k c potassium M pi c Phosphate

Kinetic Law

v566 = not speciﬁed (1132)

6.567 Reaction R Kt3r This is a reversible reaction of two reactants forming two products.

Name potassium proton antiporter

Reaction equation M h e + M k c )−−−−* M h c + M k e (1133)

Reactants

Table 1051: Properties of each reactant. Id Name SBO M h e H+ M k c potassium

Products

Table 1052: Properties of each product. Id Name SBO M h c H+ M k e potassium

Kinetic Law

v567 = not speciﬁed (1134)

Produced by SBML2LATEX 519 6.568 Reaction R LACZ This is an irreversible reaction of two reactants forming two products.

Name b-galactosidase

Reaction equation M h2o c + M lcts c −→ M gal c + M glc DASH D c (1135)

Reactants

Table 1053: Properties of each reactant. Id Name SBO M h2o c H2O M lcts c Lactose

Products

Table 1054: Properties of each product. Id Name SBO M gal c D-Galactose M glc DASH D c D-Glucose

Kinetic Law

v568 = not speciﬁed (1136)

6.569 Reaction R LCTSabc This is an irreversible reaction of three reactants forming four products.

Name lactose transport via ABC system (import)

Reaction equation M atp c + M h2o c + M lcts e −→ M adp c + M h c + M lcts c + M pi c (1137)

Reactants

520 Produced by SBML2LATEX Table 1055: Properties of each reactant. Id Name SBO M atp c ATP M h2o c H2O M lcts e Lactose

Products

Table 1056: Properties of each product. Id Name SBO M adp c ADP M h c H+ M lcts c Lactose M pi c Phosphate

Kinetic Law

v569 = not speciﬁed (1138)

6.570 Reaction R LDH L This is a reversible reaction of two reactants forming three products.

Name L-lactate dehydrogenase

Reaction equation M lac DASH L c + M nad c )−−−−* M h c + M nadh c + M pyr c (1139)

Reactants

Table 1057: Properties of each reactant. Id Name SBO M lac DASH L c L-Lactate M nad c Nicotinamide adenine dinucleotide

Products

Produced by SBML2LATEX 521 Table 1058: Properties of each product. Id Name SBO M h c H+ M nadh c Nicotinamide adenine dinucleotide - reduced M pyr c Pyruvate

Kinetic Law

v570 = not speciﬁed (1140)

6.571 Reaction R LEUTA This is a reversible reaction of two reactants forming two products.

Name leucine transaminase

Reaction equation M akg c + M leu DASH L c )−−−−* M 4mop c + M glu DASH L c (1141)

Reactants

Table 1059: Properties of each reactant. Id Name SBO M akg c 2-Oxoglutarate M leu DASH L c L-Leucine

Products

Table 1060: Properties of each product. Id Name SBO M 4mop c 4-Methyl-2-oxopentanoate M glu DASH L c L-Glutamate

Kinetic Law

v571 = not speciﬁed (1142)

522 Produced by SBML2LATEX 6.572 Reaction R LEUt2r This is a reversible reaction of two reactants forming two products.

Name L-leucine reversible transport via proton symport

Reaction equation M h e + M leu DASH L e )−−−−* M h c + M leu DASH L c (1143)

Reactants

Table 1061: Properties of each reactant. Id Name SBO M h e H+ M leu DASH L e L-Leucine

Products

Table 1062: Properties of each product. Id Name SBO M h c H+ M leu DASH L c L-Leucine

Kinetic Law

v572 = not speciﬁed (1144)

6.573 Reaction R LO This is an irreversible reaction of two reactants forming three products.

Name L-lactate oxidase

Reaction equation M lac DASH L c + M o2 c −→ M ac c + M co2 c + M h2o c (1145)

Reactants

Produced by SBML2LATEX 523 Table 1063: Properties of each reactant. Id Name SBO M lac DASH L c L-Lactate M o2 c O2

Products

Table 1064: Properties of each product. Id Name SBO M ac c Acetate M co2 c CO2 M h2o c H2O

Kinetic Law

v573 = not speciﬁed (1146)

6.574 Reaction R LPLIPAL2E160 This is an irreversible reaction of two reactants forming three products.

Name Lysophospholipase L2 (2-acylglycerophosphoethanolamine, n-C16:0)

Reaction equation M 2agpe160 c + M h2o c −→ M g3pe c + M h c + M hdca c (1147)

Reactants

Table 1065: Properties of each reactant. Id Name SBO M 2agpe160 c 2-Acyl-sn-glycero-3-phosphoethanolamine (n-C16:0) M h2o c H2O

Products

524 Produced by SBML2LATEX Table 1066: Properties of each product. Id Name SBO M g3pe c sn-Glycero-3-phosphoethanolamine M h c H+ M hdca c Hexadecanoate (n-C16:0)

Kinetic Law

v574 = not speciﬁed (1148)

6.575 Reaction R LPLIPAL2E180 This is an irreversible reaction of two reactants forming three products.

Name Lysophospholipase L2 (2-acylglycerophosphoethanolamine, n-C18:0)

Reaction equation M 2agpe180 c + M h2o c −→ M g3pe c + M h c + M ocdca c (1149)

Reactants

Table 1067: Properties of each reactant. Id Name SBO M 2agpe180 c 2-Acyl-sn-glycero-3-phosphoethanolamine (n-C18:0) M h2o c H2O

Products

Table 1068: Properties of each product. Id Name SBO M g3pe c sn-Glycero-3-phosphoethanolamine M h c H+ M ocdca c octadecanoate (n-C18:0)

Kinetic Law

v575 = not speciﬁed (1150)

Produced by SBML2LATEX 525 6.576 Reaction R LYSt5r This is a reversible reaction of one reactant forming one product.

Name L-lysine transport via diffusion

Reaction equation M lys DASH L e )−−−−* M lys DASH L c (1151)

Reactant

Table 1069: Properties of each reactant. Id Name SBO M lys DASH L e L-Lysine

Product

Table 1070: Properties of each product. Id Name SBO M lys DASH L c L-Lysine

Kinetic Law

v576 = not speciﬁed (1152)

6.577 Reaction R L LACD This is an irreversible reaction of two reactants forming two products.

Name L-Lactate dehydrogenase irreversible

Reaction equation 2M ﬁcytc c + M lac DASH L c −→ 2M focytc c + M pyr c (1153)

Reactants

526 Produced by SBML2LATEX Table 1071: Properties of each reactant. Id Name SBO M ficytc c Ferricytochrome c M lac DASH L c L-Lactate

Products

Table 1072: Properties of each product. Id Name SBO M focytc c Ferrocytochrome c M pyr c Pyruvate

Kinetic Law

v577 = not speciﬁed (1154)

6.578 Reaction R L LACD2 This is an irreversible reaction of two reactants forming two products.

Name L-Lactate dehydrogenase (ubiquinone)

Reaction equation M lac DASH L c + M q8 c −→ M pyr c + M q8h2 c (1155)

Reactants

Table 1073: Properties of each reactant. Id Name SBO M lac DASH L c L-Lactate M q8 c Ubiquinone-8

Products

Table 1074: Properties of each product. Id Name SBO M pyr c Pyruvate

Produced by SBML2LATEX 527 Id Name SBO M q8h2 c Ubiquinol-8

Kinetic Law

v578 = not speciﬁed (1156)

6.579 Reaction R L LACD3 This is an irreversible reaction of two reactants forming two products.

Name L-Lactate dehydrogenase (menaquinone)

Reaction equation M lac DASH L c + M mqn8 c −→ M mql8 c + M pyr c (1157)

Reactants

Table 1075: Properties of each reactant. Id Name SBO M lac DASH L c L-Lactate M mqn8 c Menaquinone 8

Products

Table 1076: Properties of each product. Id Name SBO M mql8 c Menaquinol 8 M pyr c Pyruvate

Kinetic Law

v579 = not speciﬁed (1158)

6.580 Reaction R L LACt2r This is a reversible reaction of two reactants forming two products.

Name L-lactate reversible transport via proton symport

528 Produced by SBML2LATEX Reaction equation M h e + M lac DASH L e )−−−−* M h c + M lac DASH L c (1159)

Reactants

Table 1077: Properties of each reactant. Id Name SBO M h e H+ M lac DASH L e L-Lactate

Products

Table 1078: Properties of each product. Id Name SBO M h c H+ M lac DASH L c L-Lactate

Kinetic Law

v580 = not speciﬁed (1160)

6.581 Reaction R L LACt3 This is an irreversible reaction of two reactants forming two products.

Name L-lactate transport out via proton antiport

Reaction equation M h e + M lac DASH L c −→ M h c + M lac DASH L e (1161)

Reactants

Table 1079: Properties of each reactant. Id Name SBO M h e H+ M lac DASH L c L-Lactate

Produced by SBML2LATEX 529 Products

Table 1080: Properties of each product. Id Name SBO M h c H+ M lac DASH L e L-Lactate

Kinetic Law

v581 = not speciﬁed (1162)

6.582 Reaction R MALS This is an irreversible reaction of three reactants forming three products.

Name malate synthase

Reaction equation M accoa c + M glx c + M h2o c −→ M coa c + M h c + M mal DASH L c (1163)

Reactants

Table 1081: Properties of each reactant. Id Name SBO M accoa c Acetyl-CoA M glx c Glyoxylate M h2o c H2O

Products

Table 1082: Properties of each product. Id Name SBO M coa c Coenzyme A M h c H+ M mal DASH L c L-Malate

530 Produced by SBML2LATEX Kinetic Law

v582 = not speciﬁed (1164)

6.583 Reaction R MALT This is an irreversible reaction of two reactants forming one product.

Name alpha-glucosidase

Reaction equation M h2o c + M malt c −→ 2M glc DASH D c (1165)

Reactants

Table 1083: Properties of each reactant. Id Name SBO M h2o c H2O M malt c Maltose

Product

Table 1084: Properties of each product. Id Name SBO M glc DASH D c D-Glucose

Kinetic Law

v583 = not speciﬁed (1166)

6.584 Reaction R MALTHPabc This is an irreversible reaction of three reactants forming four products.

Name maltoheptaose transport via ABC system

Reaction equation

M atp c + M h2o c + M malthp e −→ M adp c + M h c + M malthp c + M pi c (1167)

Produced by SBML2LATEX 531 Reactants

532 Produced by SBML2LATEX Table 1085: Properties of each reactant. Id Name SBO M atp c ATP M h2o c H2O M malthp e Maltoheptaose

Products

Table 1086: Properties of each product. Id Name SBO M adp c ADP M h c H+ M malthp c Maltoheptaose M pi c Phosphate

Kinetic Law

v584 = not speciﬁed (1168)

6.585 Reaction R MALTabc This is an irreversible reaction of three reactants forming four products.

Name maltose transport via ABC system

Reaction equation M atp c + M h2o c + M malt e −→ M adp c + M h c + M malt c + M pi c (1169)

Reactants

Table 1087: Properties of each reactant. Id Name SBO M atp c ATP M h2o c H2O M malt e Maltose

Products

Produced by SBML2LATEX 533 Table 1088: Properties of each product. Id Name SBO M adp c ADP M h c H+ M malt c Maltose M pi c Phosphate

Kinetic Law

v585 = not speciﬁed (1170)

6.586 Reaction R MALt2r This is a reversible reaction of two reactants forming two products.

Name L-malate reversible transport via proton symport

Reaction equation M h e + M mal DASH L e )−−−−* M h c + M mal DASH L c (1171)

Reactants

Table 1089: Properties of each reactant. Id Name SBO M h e H+ M mal DASH L e L-Malate

Products

Table 1090: Properties of each product. Id Name SBO M h c H+ M mal DASH L c L-Malate

Kinetic Law

v586 = not speciﬁed (1172)

534 Produced by SBML2LATEX 6.587 Reaction R MAN1PT This is an irreversible reaction of three reactants forming two products.

Name mannose-1-phosphate guanylyltransferase

Reaction equation M gtp c + M h c + M man1p c −→ M gdpmann c + M ppi c (1173)

Reactants

Table 1091: Properties of each reactant. Id Name SBO M gtp c GTP M h c H+ M man1p c D-Mannose 1-phosphate

Products

Table 1092: Properties of each product. Id Name SBO M gdpmann c GDP-D-mannose M ppi c Diphosphate

Kinetic Law

v587 = not speciﬁed (1174)

6.588 Reaction R MAN1PT2 This is an irreversible reaction of three reactants forming two products.

Name mannose-1-phosphate guanylyltransferase (GDP)

Reaction equation M gdp c + M h c + M man1p c −→ M gdpmann c + M pi c (1175)

Reactants

Produced by SBML2LATEX 535 Table 1093: Properties of each reactant. Id Name SBO M gdp c GDP M h c H+ M man1p c D-Mannose 1-phosphate

Products

Table 1094: Properties of each product. Id Name SBO M gdpmann c GDP-D-mannose M pi c Phosphate

Kinetic Law

v588 = not speciﬁed (1176)

6.589 Reaction R MAN6PI This is a reversible reaction of one reactant forming one product.

Name mannose-6-phosphate isomerase

Reaction equation M man6p c )−−−−* M f6p c (1177)

Reactant

Table 1095: Properties of each reactant. Id Name SBO M man6p c D-Mannose 6-phosphate

Product

Table 1096: Properties of each product. Id Name SBO M f6p c D-Fructose 6-phosphate

536 Produced by SBML2LATEX Id Name SBO

Kinetic Law

v589 = not speciﬁed (1178)

6.590 Reaction R MANAT1 This is an irreversible reaction of two reactants forming two products.

Name mannosyl acyl transferase

Reaction equation M PIM1 c + M pmtcoa c −→ M Ac1PIM1 c + M coa c (1179)

Reactants

Table 1097: Properties of each reactant. Id Name SBO M PIM1 c phosphatidylinositol mannoside (tuberculosis) M pmtcoa c Palmitoyl-CoA (n-C16:0CoA)

Products

Table 1098: Properties of each product. Id Name SBO M Ac1PIM1 c acyl phosphatidylinositol mannoside (tuberculosis) M coa c Coenzyme A

Kinetic Law

v590 = not speciﬁed (1180)

6.591 Reaction R MANAT2 This is an irreversible reaction of two reactants forming two products.

Name mannosyl acyl transferase

Produced by SBML2LATEX 537 Reaction equation M PIM2 c + M pmtcoa c −→ M Ac1PIM2 c + M coa c (1181)

Reactants

Table 1099: Properties of each reactant. Id Name SBO M PIM2 c phosphatidylinositol mannoside di-mannose (tuberculosis) M pmtcoa c Palmitoyl-CoA (n-C16:0CoA)

Products

Table 1100: Properties of each product. Id Name SBO M Ac1PIM2 c acyl phosphatidylinositol mannoside di-mannose (tuberculosis) M coa c Coenzyme A

Kinetic Law

v591 = not speciﬁed (1182)

6.592 Reaction R MANAT3 This is an irreversible reaction of two reactants forming two products.

Name mannosyl acyl transferase

Reaction equation M Ac1PIM2 c + M pmtcoa c −→ M Ac2PIM2 c + M coa c (1183)

Reactants

Table 1101: Properties of each reactant. Id Name SBO M Ac1PIM2 c acyl phosphatidylinositol mannoside di-mannose (tuberculosis) M pmtcoa c Palmitoyl-CoA (n-C16:0CoA)

538 Produced by SBML2LATEX Products

Table 1102: Properties of each product. Id Name SBO M Ac2PIM2 c di-acyl phosphatidylinositol mannoside di-mannose (tuberculosis) M coa c Coenzyme A

Kinetic Law

v592 = not speciﬁed (1184)

6.593 Reaction R MCBTS This is an irreversible reaction of eight reactants forming six products.

Name mycobactin synthesis

Reaction equation M atp c + M bhb c + M h c + 2M lys DASH L c + 2M o2 c + M odecoa c + M salc c + M thr DASH L c −→ M adp c + M co2 c + M coa c + 5M h2o c + M mcbts c + M pi c (1185)

Reactants

Table 1103: Properties of each reactant. Id Name SBO M atp c ATP M bhb c (R)-3-Hydroxybutanoate M h c H+ M lys DASH L c L-Lysine M o2 c O2 M odecoa c Octadecenoyl-CoA (n-C18:1CoA) M salc c Salicylate M thr DASH L c L-Threonine

Products

Produced by SBML2LATEX 539 Table 1104: Properties of each product. Id Name SBO M adp c ADP M co2 c CO2 M coa c Coenzyme A M h2o c H2O M mcbts c mycobactin S M pi c Phosphate

Kinetic Law

v593 = not speciﬁed (1186)

6.594 Reaction R MCBTS2 This is an irreversible reaction of eight reactants forming six products.

Name mycobactin synthesis

Reaction equation M atp c + M bhb c + M h c + 2M lys DASH L c + 2M o2 c + M odecoa c + M salc c + M ser DASH L c −→ M adp c + M co2 c + M coa c + 5M h2o c + M mcbtt c + M pi c (1187)

Reactants

Table 1105: Properties of each reactant. Id Name SBO M atp c ATP M bhb c (R)-3-Hydroxybutanoate M h c H+ M lys DASH L c L-Lysine M o2 c O2 M odecoa c Octadecenoyl-CoA (n-C18:1CoA) M salc c Salicylate M ser DASH L c L-Serine

Products

540 Produced by SBML2LATEX Table 1106: Properties of each product. Id Name SBO M adp c ADP M co2 c CO2 M coa c Coenzyme A M h2o c H2O M mcbtt c mycobactin T M pi c Phosphate

Kinetic Law

v594 = not speciﬁed (1188)

6.595 Reaction R MCBTS3 This is an irreversible reaction of eight reactants forming eight products.

Name carboxymycobactin synthesis

Reaction equation M atp c + M bhb c + 2M lys DASH L c + 2M nadp c + 3·5M o2 c + M occoa c + M salc c + M ser DASH L c −→ M adp c + M cmcbtt c + M co2 c + M coa c + 5M h2o c + 2M h c + 2M nadph c + M pi c (1189)

Reactants

Table 1107: Properties of each reactant. Id Name SBO M atp c ATP M bhb c (R)-3-Hydroxybutanoate M lys DASH L c L-Lysine M nadp c Nicotinamide adenine dinucleotide phosphate M o2 c O2 M occoa c Octanoyl-CoA (n-C8:0CoA) M salc c Salicylate M ser DASH L c L-Serine

Products

Produced by SBML2LATEX 541 Table 1108: Properties of each product. Id Name SBO M adp c ADP M cmcbtt c carboxymycobactin T (R=8 carbon, ﬁnal carbon is carboxyl group) M co2 c CO2 M coa c Coenzyme A M h2o c H2O M h c H+ M nadph c Nicotinamide adenine dinucleotide phosphate - reduced M pi c Phosphate

Kinetic Law

v595 = not speciﬁed (1190)

6.596 Reaction R MCD This is an irreversible reaction of two reactants forming two products.

Name Malonyl-CoA Decarboxylase cytoplasmic

Reaction equation M h c + M malcoa c −→ M accoa c + M co2 c (1191)

Reactants

Table 1109: Properties of each reactant. Id Name SBO M h c H+ M malcoa c Malonyl-CoA

Products

Table 1110: Properties of each product. Id Name SBO M accoa c Acetyl-CoA M co2 c CO2

542 Produced by SBML2LATEX Kinetic Law

v596 = not speciﬁed (1192)

6.597 Reaction R MCOATA This is a reversible reaction of two reactants forming two products.

Name Malonyl-CoA-ACP transacylase

Reaction equation M ACP c + M malcoa c )−−−−* M coa c + M malACP c (1193)

Reactants

Table 1111: Properties of each reactant. Id Name SBO M ACP c acyl carrier protein M malcoa c Malonyl-CoA

Products

Table 1112: Properties of each product. Id Name SBO M coa c Coenzyme A M malACP c Malonyl-[acyl-carrier protein]

Kinetic Law

v597 = not speciﬁed (1194)

6.598 Reaction R MDFDH This is a reversible reaction of two reactants forming three products.

Name mycothiol dependent formaldehyde dehydrogenase

Reaction equation

M mshfald c + M nad c )−−−−* M h c + M mshfaldox c + M nadh c (1195)

Produced by SBML2LATEX 543 Reactants

Table 1113: Properties of each reactant. Id Name SBO M mshfald c mycothiol conjugated methanol M nad c Nicotinamide adenine dinucleotide

Products

Table 1114: Properties of each product. Id Name SBO M h c H+ M mshfaldox c mycothiol conjugated aldehyde M nadh c Nicotinamide adenine dinucleotide - reduced

Kinetic Law

v598 = not speciﬁed (1196)

6.599 Reaction R MDH This is a reversible reaction of two reactants forming three products.

Name malate dehydrogenase

Reaction equation M mal DASH L c + M nad c )−−−−* M h c + M nadh c + M oaa c (1197)

Reactants

Table 1115: Properties of each reactant. Id Name SBO M mal DASH L c L-Malate M nad c Nicotinamide adenine dinucleotide

Products

544 Produced by SBML2LATEX Table 1116: Properties of each product. Id Name SBO M h c H+ M nadh c Nicotinamide adenine dinucleotide - reduced M oaa c Oxaloacetate

Kinetic Law

v599 = not speciﬁed (1198)

6.600 Reaction R ME1 This is an irreversible reaction of two reactants forming three products.

Name malic enzyme (NAD)

Reaction equation M mal DASH L c + M nad c −→ M co2 c + M nadh c + M pyr c (1199)

Reactants

Table 1117: Properties of each reactant. Id Name SBO M mal DASH L c L-Malate M nad c Nicotinamide adenine dinucleotide

Products

Table 1118: Properties of each product. Id Name SBO M co2 c CO2 M nadh c Nicotinamide adenine dinucleotide - reduced M pyr c Pyruvate

Kinetic Law

v600 = not speciﬁed (1200)

Produced by SBML2LATEX 545 6.601 Reaction R MECDPDH This is an irreversible reaction of two reactants forming two products.

Name 2C-methyl-D-erythritol 2,4 cyclodiphosphate dehydratase

Reaction equation M 2mecdp c + M h c −→ M h2mb4p c + M h2o c (1201)

Reactants

Table 1119: Properties of each reactant. Id Name SBO M 2mecdp c 2-C-methyl-D-erythritol 2,4-cyclodiphosphate M h c H+

Products

Table 1120: Properties of each product. Id Name SBO M h2mb4p c 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate M h2o c H2O

Kinetic Law

v601 = not speciﬁed (1202)

6.602 Reaction R MECDPS This is an irreversible reaction of one reactant forming two products.

Name 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

Reaction equation M 2p4c2me c −→ M 2mecdp c + M cmp c (1203)

Reactant

546 Produced by SBML2LATEX Table 1121: Properties of each reactant. Id Name SBO M 2p4c2me c 2-phospho-4-(cytidine 5’-diphospho)-2-C-methyl-D-erythritol

Products

Table 1122: Properties of each product. Id Name SBO M 2mecdp c 2-C-methyl-D-erythritol 2,4-cyclodiphosphate M cmp c CMP

Kinetic Law

v602 = not speciﬁed (1204)

6.603 Reaction R MEOHt2 This is a reversible reaction of one reactant forming one product.

Name Methanol diffusion

Reaction equation M meoh e )−−−−* M meoh c (1205)

Reactant

Table 1123: Properties of each reactant. Id Name SBO M meoh e Methanol

Product

Table 1124: Properties of each product. Id Name SBO M meoh c Methanol

Produced by SBML2LATEX 547 Kinetic Law

v603 = not speciﬁed (1206)

6.604 Reaction R MEPCT This is an irreversible reaction of three reactants forming two products.

Name 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase

Reaction equation M 2me4p c + M ctp c + M h c −→ M 4c2me c + M ppi c (1207)

Reactants

Table 1125: Properties of each reactant. Id Name SBO M 2me4p c 2-C-methyl-D-erythritol 4-phosphate M ctp c CTP M h c H+

Products

Table 1126: Properties of each product. Id Name SBO M 4c2me c 4-(cytidine 5’-diphospho)-2-C-methyl-D-erythritol M ppi c Diphosphate

Kinetic Law

v604 = not speciﬁed (1208)

6.605 Reaction R METAT This is an irreversible reaction of three reactants forming three products.

Name methionine adenosyltransferase

Reaction equation M atp c + M h2o c + M met DASH L c −→ M amet c + M pi c + M ppi c (1209)

548 Produced by SBML2LATEX Reactants

Table 1127: Properties of each reactant. Id Name SBO M atp c ATP M h2o c H2O M met DASH L c L-Methionine

Products

Table 1128: Properties of each product. Id Name SBO M amet c S-Adenosyl-L-methionine M pi c Phosphate M ppi c Diphosphate

Kinetic Law

v605 = not speciﬁed (1210)

6.606 Reaction R METOX1s This is an irreversible reaction of two reactants forming two products.

Name methionine oxidation (spontaneous)

Reaction equation M h2o2 c + M met DASH L c −→ M h2o c + M metsox DASH S DASH L c (1211)

Reactants

Table 1129: Properties of each reactant. Id Name SBO M h2o2 c Hydrogen peroxide M met DASH L c L-Methionine

Products

Produced by SBML2LATEX 549 Table 1130: Properties of each product. Id Name SBO M h2o c H2O M metsox DASH S DASH L c L-Methionine Sulfoxide

Kinetic Law

v606 = not speciﬁed (1212)

6.607 Reaction R METOX2s This is an irreversible reaction of two reactants forming two products.

Name methionine oxidation 2 (spontaneous)

Reaction equation M h2o2 c + M met DASH L c −→ M h2o c + M metsox DASH R DASH L c (1213)

Reactants

Table 1131: Properties of each reactant. Id Name SBO M h2o2 c Hydrogen peroxide M met DASH L c L-Methionine

Products

Table 1132: Properties of each product. Id Name SBO M h2o c H2O M metsox DASH R DASH L c L-methionine-R-sulfoxide

Kinetic Law

v607 = not speciﬁed (1214)

6.608 Reaction R METS This is an irreversible reaction of two reactants forming three products.

550 Produced by SBML2LATEX Name methionine synthase

Reaction equation M 5mthf c + M hcys DASH L c −→ M h c + M met DASH L c + M thf c (1215)

Reactants

Table 1133: Properties of each reactant. Id Name SBO M 5mthf c 5-Methyltetrahydrofolate M hcys DASH L c L-Homocysteine

Products

Table 1134: Properties of each product. Id Name SBO M h c H+ M met DASH L c L-Methionine M thf c 5,6,7,8-Tetrahydrofolate

Kinetic Law

v608 = not speciﬁed (1216)

6.609 Reaction R METSOXR1 This is an irreversible reaction of two reactants forming three products.

Name L-methionine-S-oxide reductase

Reaction equation M metsox DASH S DASH L c + M trdrd c −→ M h2o c + M met DASH L c + M trdox c (1217)

Reactants

Produced by SBML2LATEX 551 Table 1135: Properties of each reactant. Id Name SBO M metsox DASH S DASH L c L-Methionine Sulfoxide M trdrd c Reduced thioredoxin

Products

Table 1136: Properties of each product. Id Name SBO M h2o c H2O M met DASH L c L-Methionine M trdox c Oxidized thioredoxin

Kinetic Law

v609 = not speciﬁed (1218)

6.610 Reaction R METSOXR2 This is an irreversible reaction of two reactants forming three products.

Name L-methionine-R-sulfoxide reductase

Reaction equation M metsox DASH R DASH L c + M trdrd c −→ M h2o c + M met DASH L c + M trdox c (1219)

Reactants

Table 1137: Properties of each reactant. Id Name SBO M metsox DASH R DASH L c L-methionine-R-sulfoxide M trdrd c Reduced thioredoxin

Products

552 Produced by SBML2LATEX Table 1138: Properties of each product. Id Name SBO M h2o c H2O M met DASH L c L-Methionine M trdox c Oxidized thioredoxin

Kinetic Law

v610 = not speciﬁed (1220)

6.611 Reaction R METabc This is an irreversible reaction of three reactants forming four products.

Name L-methionine transport via ABC system

Reaction equation M atp c + M h2o c + M met DASH L e −→ M adp c + M h c + M met DASH L c + M pi c (1221)

Reactants

Table 1139: Properties of each reactant. Id Name SBO M atp c ATP M h2o c H2O M met DASH L e L-Methionine

Products

Table 1140: Properties of each product. Id Name SBO M adp c ADP M h c H+ M met DASH L c L-Methionine M pi c Phosphate

Produced by SBML2LATEX 553 Kinetic Law

v611 = not speciﬁed (1222)

6.612 Reaction R MGt5 This is a reversible reaction of one reactant forming one product.

Name magnesium transport in/out via permease (no H+)

Reaction equation M mg2 c )−−−−* M mg2 e (1223)

Reactant

Table 1141: Properties of each reactant. Id Name SBO M mg2 c magnesium

Product

Table 1142: Properties of each product. Id Name SBO M mg2 e magnesium

Kinetic Law

v612 = not speciﬁed (1224)

6.613 Reaction R MHPGLUT This is an irreversible reaction of two reactants forming two products. Name 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase

Reaction equation M hcys DASH L c + M mhpglu c −→ M hpglu c + M met DASH L c (1225)

Reactants

554 Produced by SBML2LATEX Table 1143: Properties of each reactant. Id Name SBO M hcys DASH L c L-Homocysteine M mhpglu c 5-Methyltetrahydropteroyltri-L-glutamate

Products

Table 1144: Properties of each product. Id Name SBO M hpglu c Tetrahydropteroyltri-L-glutamate M met DASH L c L-Methionine

Kinetic Law

v613 = not speciﬁed (1226)

6.614 Reaction R MI1PP This is an irreversible reaction of two reactants forming two products.

Name myo-inositol 1-phosphatase

Reaction equation M h2o c + M mi1p DASH D c −→ M inost c + M pi c (1227)

Reactants

Table 1145: Properties of each reactant. Id Name SBO M h2o c H2O M mi1p DASH D c 1D-myo-Inositol 1-phosphate

Products

Table 1146: Properties of each product. Id Name SBO M inost c myo-Inositol

Produced by SBML2LATEX 555 Id Name SBO M pi c Phosphate

Kinetic Law

v614 = not speciﬁed (1228)

6.615 Reaction R MI1PS This is an irreversible reaction of one reactant forming one product.

Name myo-Inositol-1-phosphate synthase

Reaction equation M g6p c −→ M mi1p DASH D c (1229)

Reactant

Table 1147: Properties of each reactant. Id Name SBO M g6p c D-Glucose 6-phosphate

Product

Table 1148: Properties of each product. Id Name SBO M mi1p DASH D c 1D-myo-Inositol 1-phosphate

Kinetic Law

v615 = not speciﬁed (1230)

6.616 Reaction R MI3PP

This is an irreversible reaction of two reactants forming two products.

Name myo-inositol 3-phosphatase

556 Produced by SBML2LATEX Reaction equation M h2o c + M mi3p DASH D c −→ M inost c + M pi c (1231)

Reactants

Table 1149: Properties of each reactant. Id Name SBO M h2o c H2O M mi3p DASH D c 1D-myo-Inositol 3-phosphate

Products

Table 1150: Properties of each product. Id Name SBO M inost c myo-Inositol M pi c Phosphate

Kinetic Law

v616 = not speciﬁed (1232)

6.617 Reaction R MI4PP This is an irreversible reaction of two reactants forming two products.

Name myo-inositol 4-phosphatase

Reaction equation M h2o c + M mi4p DASH D c −→ M inost c + M pi c (1233)

Reactants

Table 1151: Properties of each reactant. Id Name SBO M h2o c H2O M mi4p DASH D c 1D-myo-Inositol 4-phosphate

Produced by SBML2LATEX 557 Products

Table 1152: Properties of each product. Id Name SBO M inost c myo-Inositol M pi c Phosphate

Kinetic Law

v617 = not speciﬁed (1234)

6.618 Reaction R MMCD This is an irreversible reaction of two reactants forming two products.

Name Methylmalonyl-CoA decarboxylase

Reaction equation M h c + M mmcoa DASH S c −→ M co2 c + M ppcoa c (1235)

Reactants

Table 1153: Properties of each reactant. Id Name SBO M h c H+ M mmcoa DASH S c (S)-Methylmalonyl-CoA

Products

Table 1154: Properties of each product. Id Name SBO M co2 c CO2 M ppcoa c Propanoyl-CoA

Kinetic Law

v618 = not speciﬁed (1236)

558 Produced by SBML2LATEX 6.619 Reaction R MME This is a reversible reaction of one reactant forming one product.

Name methylmalonyl-CoA epimerase

Reaction equation M mmcoa DASH R c )−−−−* M mmcoa DASH S c (1237)

Reactant

Table 1155: Properties of each reactant. Id Name SBO M mmcoa DASH R c (R)-Methylmalonyl-CoA

Product

Table 1156: Properties of each product. Id Name SBO M mmcoa DASH S c (S)-Methylmalonyl-CoA

Kinetic Law

v619 = not speciﬁed (1238)

6.620 Reaction R MMM2r This is a reversible reaction of one reactant forming one product.

Name Methylmalonyl-CoA mutase

Reaction equation M succoa c )−−−−* M mmcoa DASH R c (1239)

Reactant

Produced by SBML2LATEX 559 Table 1157: Properties of each reactant. Id Name SBO M succoa c Succinyl-CoA

Product

Table 1158: Properties of each product. Id Name SBO M mmcoa DASH R c (R)-Methylmalonyl-CoA

Kinetic Law

v620 = not speciﬁed (1240)

6.621 Reaction R MMSAD1 This is an irreversible reaction of three reactants forming three products.

Name methylmalonate-semialdehyde dehydrogenase

Reaction equation M 2mop c + M coa c + M nad c −→ M co2 c + M nadh c + M ppcoa c (1241)

Reactants

Table 1159: Properties of each reactant. Id Name SBO M 2mop c 2-Methyl-3-oxopropanoate M coa c Coenzyme A M nad c Nicotinamide adenine dinucleotide

Products

Table 1160: Properties of each product. Id Name SBO M co2 c CO2 M nadh c Nicotinamide adenine dinucleotide - reduced

560 Produced by SBML2LATEX Id Name SBO M ppcoa c Propanoyl-CoA

Kinetic Law

v621 = not speciﬁed (1242)

6.622 Reaction R MMSAD2 This is an irreversible reaction of three reactants forming three products.

Name methylmalonate-semialdehyde dehydrogenase (propanol)

Reaction equation M coa c + M nad c + M ppal c −→ M h c + M nadh c + M ppcoa c (1243)

Reactants

Table 1161: Properties of each reactant. Id Name SBO M coa c Coenzyme A M nad c Nicotinamide adenine dinucleotide M ppal c Propanal

Products

Table 1162: Properties of each product. Id Name SBO M h c H+ M nadh c Nicotinamide adenine dinucleotide - reduced M ppcoa c Propanoyl-CoA

Kinetic Law

v622 = not speciﬁed (1244)

6.623 Reaction R MMSAD3 This is an irreversible reaction of three reactants forming three products.

Produced by SBML2LATEX 561 Name methylmalonate-semialdehyde dehydrogenase (malonic semialdehyde)

Reaction equation M coa c + M msa c + M nad c −→ M accoa c + M co2 c + M nadh c (1245)

Reactants

Table 1163: Properties of each reactant. Id Name SBO M coa c Coenzyme A M msa c Malonate semialdehyde M nad c Nicotinamide adenine dinucleotide

Products

Table 1164: Properties of each product. Id Name SBO M accoa c Acetyl-CoA M co2 c CO2 M nadh c Nicotinamide adenine dinucleotide - reduced

Kinetic Law

v623 = not speciﬁed (1246)

6.624 Reaction R MN6PP This is an irreversible reaction of two reactants forming two products.

Name mannose 6-phosphate phosphatase

Reaction equation M h2o c + M man6p c −→ M man c + M pi c (1247)

Reactants

562 Produced by SBML2LATEX Table 1165: Properties of each reactant. Id Name SBO M h2o c H2O M man6p c D-Mannose 6-phosphate

Products

Table 1166: Properties of each product. Id Name SBO M man c D-Mannose M pi c Phosphate

Kinetic Law

v624 = not speciﬁed (1248)

6.625 Reaction R MNDNS1 This is an irreversible reaction of three reactants forming three products.

Name menadione synthase

Reaction equation M dhna c + 3M h c + 2M nadph c −→ 2M h2o c + M mndn c + 2M nadp c (1249)

Reactants

Table 1167: Properties of each reactant. Id Name SBO M dhna c 1,4-Dihydroxy-2-naphthoate M h c H+ M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

Products

Produced by SBML2LATEX 563 Table 1168: Properties of each product. Id Name SBO M h2o c H2O M mndn c menadione M nadp c Nicotinamide adenine dinucleotide phosphate

Kinetic Law

v625 = not speciﬁed (1250)

6.626 Reaction R MNDNS2 This is an irreversible reaction of three reactants forming three products.

Name menadione synthase

Reaction equation M dhna c + 3M h c + 2M nadh c −→ 2M h2o c + M mndn c + 2M nad c (1251)

Reactants

Table 1169: Properties of each reactant. Id Name SBO M dhna c 1,4-Dihydroxy-2-naphthoate M h c H+ M nadh c Nicotinamide adenine dinucleotide - reduced

Products

Table 1170: Properties of each product. Id Name SBO M h2o c H2O M mndn c menadione M nad c Nicotinamide adenine dinucleotide

Kinetic Law

v626 = not speciﬁed (1252)

564 Produced by SBML2LATEX 6.627 Reaction R MOHMT This is an irreversible reaction of three reactants forming two products.

Name 3-methyl-2-oxobutanoate hydroxymethyltransferase

Reaction equation M 3mob c + M h2o c + M mlthf c −→ M 2dhp c + M thf c (1253)

Reactants

Table 1171: Properties of each reactant. Id Name SBO M 3mob c 3-Methyl-2-oxobutanoate M h2o c H2O M mlthf c 5,10-Methylenetetrahydrofolate

Products

Table 1172: Properties of each product. Id Name SBO M 2dhp c 2-Dehydropantoate M thf c 5,6,7,8-Tetrahydrofolate

Kinetic Law

v627 = not speciﬁed (1254)

6.628 Reaction R MOTH This is an irreversible reaction of two reactants forming two products.

Name maltooligosyltrehalose trehalohydrolase

Reaction equation M h2o c + M motre c −→ M maltpt c + M tre c (1255)

Reactants

Produced by SBML2LATEX 565 Table 1173: Properties of each reactant. Id Name SBO M h2o c H2O M motre c maltooligosyltrehalose

Products

Table 1174: Properties of each product. Id Name SBO M maltpt c Maltopentaose M tre c Trehalose

Kinetic Law

v628 = not speciﬁed (1256)

6.629 Reaction R MOTS This is an irreversible reaction of one reactant forming one product.

Name maltooligosyltrehalose synthase

Reaction equation M malthp c −→ M motre c (1257)

Reactant

Table 1175: Properties of each reactant. Id Name SBO M malthp c Maltoheptaose

Product

Table 1176: Properties of each product. Id Name SBO M motre c maltooligosyltrehalose

566 Produced by SBML2LATEX Kinetic Law

v629 = not speciﬁed (1258)

6.630 Reaction R MPML This is a reversible reaction of four reactants forming four products.

Name Mg-protoporphyrin IX magnesium-lyase

Reaction equation M atp c + M h2o c + M mg2 c + M ppp9 c )−−−−* M adp c + 3M h c + M mppp9 c + M pi c (1259)

Reactants

Table 1177: Properties of each reactant. Id Name SBO M atp c ATP M h2o c H2O M mg2 c magnesium M ppp9 c Protoporphyrin

Products

Table 1178: Properties of each product. Id Name SBO M adp c ADP M h c H+ M mppp9 c Magnesium protoporphyrin M pi c Phosphate

Kinetic Law

v630 = not speciﬁed (1260)

6.631 Reaction R MSHAMID This is an irreversible reaction of two reactants forming two products. Name conjugated glutathione amidase (Mtb)

Produced by SBML2LATEX 567 Reaction equation M bmnmsh c + M h2o c −→ M acysbmn c + M igam c (1261)

Reactants

Table 1179: Properties of each reactant. Id Name SBO M bmnmsh c bimane conjugated mycothiol (mtb) M h2o c H2O

Products

Table 1180: Properties of each product. Id Name SBO M acysbmn c acetyl-cystine-bimane M igam c 1D-myo-inositol 2-deoxy-D-glucopyranoside

Kinetic Law

v631 = not speciﬁed (1262)

6.632 Reaction R MSHOXH This is an irreversible reaction of two reactants forming three products.

Name mshfaldox hydrolysis (Mtb)

Reaction equation M h2o c + M mshfaldox c −→ M for c + M h c + M msh c (1263)

Reactants

Table 1181: Properties of each reactant. Id Name SBO M h2o c H2O M mshfaldox c mycothiol conjugated aldehyde

568 Produced by SBML2LATEX Products

Table 1182: Properties of each product. Id Name SBO M for c Formate M h c H+ M msh c mycothiol (reduced)

Kinetic Law

v632 = not speciﬁed (1264)

6.633 Reaction R MSHS This is an irreversible reaction of two reactants forming two products.

Name mycothiol synthase

Reaction equation M accoa c + M cigam c −→ M coa c + M msh c (1265)

Reactants

Table 1183: Properties of each reactant. Id Name SBO M accoa c Acetyl-CoA M cigam c cys-1D-myo-inositol 2-deoxy-D-glucopyranoside

Products

Table 1184: Properties of each product. Id Name SBO M coa c Coenzyme A M msh c mycothiol (reduced)

Kinetic Law

v633 = not speciﬁed (1266)

Produced by SBML2LATEX 569 6.634 Reaction R MTAN This is an irreversible reaction of two reactants forming two products.

Name methylthioadenosine nucleosidase

Reaction equation M 5mta c + M h2o c −→ M 5mtr c + M ade c (1267)

Reactants

Table 1185: Properties of each reactant. Id Name SBO M 5mta c 5-Methylthioadenosine M h2o c H2O

Products

Table 1186: Properties of each product. Id Name SBO M 5mtr c 5-Methylthio-D-ribose M ade c Adenine

Kinetic Law

v634 = not speciﬁed (1268)

6.635 Reaction R MTHFC This is a reversible reaction of two reactants forming two products.

Name methenyltetrahydrofolate cyclohydrolase

Reaction equation M h2o c + M methf c )−−−−* M 10fthf c + M h c (1269)

Reactants

570 Produced by SBML2LATEX Table 1187: Properties of each reactant. Id Name SBO M h2o c H2O M methf c 5,10-Methenyltetrahydrofolate

Products

Table 1188: Properties of each product. Id Name SBO M 10fthf c 10-Formyltetrahydrofolate M h c H+

Kinetic Law

v635 = not speciﬁed (1270)

6.636 Reaction R MTHFD This is a reversible reaction of two reactants forming two products.

Name methylenetetrahydrofolate dehydrogenase (NADP)

Reaction equation M mlthf c + M nadp c )−−−−* M methf c + M nadph c (1271)

Reactants

Table 1189: Properties of each reactant. Id Name SBO M mlthf c 5,10-Methylenetetrahydrofolate M nadp c Nicotinamide adenine dinucleotide phosphate

Products

Table 1190: Properties of each product. Id Name SBO M methf c 5,10-Methenyltetrahydrofolate

Produced by SBML2LATEX 571 Id Name SBO M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

Kinetic Law

v636 = not speciﬁed (1272)

6.637 Reaction R MTHFD2 This is a reversible reaction of two reactants forming two products.

Name methylenetetrahydrofolate dehydrogenase (NAD)

Reaction equation M mlthf c + M nad c )−−−−* M methf c + M nadh c (1273)

Reactants

Table 1191: Properties of each reactant. Id Name SBO M mlthf c 5,10-Methylenetetrahydrofolate M nad c Nicotinamide adenine dinucleotide

Products

Table 1192: Properties of each product. Id Name SBO M methf c 5,10-Methenyltetrahydrofolate M nadh c Nicotinamide adenine dinucleotide - reduced

Kinetic Law

v637 = not speciﬁed (1274)

6.638 Reaction R MTHFR2 This is an irreversible reaction of three reactants forming two products.

Name 5,10-methylenetetrahydrofolate reductase (NADH)

572 Produced by SBML2LATEX Reaction equation 2M h c + M mlthf c + M nadh c −→ M 5mthf c + M nad c (1275)

Reactants

Table 1193: Properties of each reactant. Id Name SBO M h c H+ M mlthf c 5,10-Methylenetetrahydrofolate M nadh c Nicotinamide adenine dinucleotide - reduced

Products

Table 1194: Properties of each product. Id Name SBO M 5mthf c 5-Methyltetrahydrofolate M nad c Nicotinamide adenine dinucleotide

Kinetic Law

v638 = not speciﬁed (1276)

6.639 Reaction R MTI This is a reversible reaction of one reactant forming one product.

Name maltose trehalose isomerase

Reaction equation M tre c )−−−−* M malt c (1277)

Reactant

Table 1195: Properties of each reactant. Id Name SBO M tre c Trehalose

Produced by SBML2LATEX 573 Product

Table 1196: Properties of each product. Id Name SBO M malt c Maltose

Kinetic Law

v639 = not speciﬁed (1278)

6.640 Reaction R MYC1CYC1 This is an irreversible reaction of two reactants forming three products.

Name Mycolic Acid Cyclopropanation

Reaction equation M amet c + M meroacidACP c −→ M ahcys c + M h c + M meroacidcyc1ACP c (1279)

Reactants

Table 1197: Properties of each reactant. Id Name SBO M amet c S-Adenosyl-L-methionine M meroacidACP c alpha meroacid ACP

Products

Table 1198: Properties of each product. Id Name SBO M ahcys c S-Adenosyl-L-homocysteine M h c H+ M meroacidcyc1ACP c cyclopropanated alpha meroacid ACP (1 cyclopropane ring)

Kinetic Law

v640 = not speciﬁed (1280)

574 Produced by SBML2LATEX 6.641 Reaction R MYC1CYC2 This is an irreversible reaction of two reactants forming three products.

Name Mycolic Acid Cyclopropanation

Reaction equation M amet c + M mmeroacidACP c −→ M ahcys c + M h c + M mmeroacidcyc1ACP c (1281)

Reactants

Table 1199: Properties of each reactant. Id Name SBO M amet c S-Adenosyl-L-methionine M mmeroacidACP c methoxy meroacid ACP

Products

Table 1200: Properties of each product. Id Name SBO M ahcys c S-Adenosyl-L-homocysteine M h c H+ M mmeroacidcyc1ACP c cyclopropanated methoxy-meroacid ACP (1 cyclopropane ring)

Kinetic Law

v641 = not speciﬁed (1282)

6.642 Reaction R MYC1CYC3 This is an irreversible reaction of two reactants forming three products.

Name Mycolic Acid Cyclopropanation

Reaction equation M amet c + M kmeroacidACP c −→ M ahcys c + M h c + M kmeroacidcyc1ACP c (1283)

Reactants

Produced by SBML2LATEX 575 Table 1201: Properties of each reactant. Id Name SBO M amet c S-Adenosyl-L-methionine M kmeroacidACP c keto meroacid ACP

Products

Table 1202: Properties of each product. Id Name SBO M ahcys c S-Adenosyl-L-homocysteine M h c H+ M kmeroacidcyc1ACP c cyclopropanated keto-meroacid ACP (1 cyclopropane ring)

Kinetic Law

v642 = not speciﬁed (1284)

6.643 Reaction R MYC1CYC4 This is an irreversible reaction of two reactants forming three products.

Name Mycolic Acid Cyclopropanation

Reaction equation M amet c + M mmmeroacidACP c −→ M ahcys c + M h c + M mmmeroacidcyc1ACP c (1285)

Reactants

Table 1203: Properties of each reactant. Id Name SBO M amet c S-Adenosyl-L-methionine M mmmeroacidACP c methyl hydroxy methoxy meroacid ACP

Products

576 Produced by SBML2LATEX Table 1204: Properties of each product. Id Name SBO M ahcys c S-Adenosyl-L-homocysteine M h c H+ M mmmeroacidcyc1ACP c cyclopropanated methyl hydroxy methoxy meroacid ACP (1 cyclopropane ring)

Kinetic Law

v643 = not speciﬁed (1286)

6.644 Reaction R MYC1CYC5 This is an irreversible reaction of two reactants forming three products.

Name Mycolic Acid Cyclopropanation

Reaction equation M amet c + M mkmeroacidACP c −→ M ahcys c + M h c + M mkmeroacidcyc1ACP c (1287)

Reactants

Table 1205: Properties of each reactant. Id Name SBO M amet c S-Adenosyl-L-methionine M mkmeroacidACP c methyl hydroxy keto meroacid ACP (1 cyclopropane ring)

Products

Table 1206: Properties of each product. Id Name SBO M ahcys c S-Adenosyl-L-homocysteine M h c H+ M mkmeroacidcyc1ACP c cyclopropanated methyl hydroxy keto meroacid ACP (1 cyclopropane ring)

Kinetic Law

v644 = not speciﬁed (1288)

Produced by SBML2LATEX 577 6.645 Reaction R MYC1M1 This is an irreversible reaction of three reactants forming three products.

Name Mycolic Acid Methyl Hydroxyl Addition

Reaction equation M amet c + M h2o c + M mmeroacidACP c −→ M ahcys c + M h c + M mmmeroacidACP c (1289)

Reactants

Table 1207: Properties of each reactant. Id Name SBO M amet c S-Adenosyl-L-methionine M h2o c H2O M mmeroacidACP c methoxy meroacid ACP

Products

Table 1208: Properties of each product. Id Name SBO M ahcys c S-Adenosyl-L-homocysteine M h c H+ M mmmeroacidACP c methyl hydroxy methoxy meroacid ACP

Kinetic Law

v645 = not speciﬁed (1290)

6.646 Reaction R MYC1M2 This is an irreversible reaction of three reactants forming three products.

Name Mycolic Acid Methyl Hydroxyl Addition

Reaction equation M amet c + M h2o c + M kmeroacidACP c −→ M ahcys c + M h c + M mkmeroacidACP c (1291)

578 Produced by SBML2LATEX Reactants

Table 1209: Properties of each reactant. Id Name SBO M amet c S-Adenosyl-L-methionine M h2o c H2O M kmeroacidACP c keto meroacid ACP

Products

Table 1210: Properties of each product. Id Name SBO M ahcys c S-Adenosyl-L-homocysteine M h c H+ M mkmeroacidACP c methyl hydroxy keto meroacid ACP (1 cyclopropane ring)

Kinetic Law

v646 = not speciﬁed (1292)

6.647 Reaction R MYC2CYC1 This is an irreversible reaction of two reactants forming three products.

Name Mycolic Acid Cyclopropanation

Reaction equation M amet c + M meroacidcyc1ACP c −→ M ahcys c + M h c + M meroacidcyc2ACP c (1293)

Reactants

Table 1211: Properties of each reactant. Id Name SBO M amet c S-Adenosyl-L-methionine M meroacidcyc1ACP c cyclopropanated alpha meroacid ACP (1 cyclopropane ring)

Produced by SBML2LATEX 579 Products

Table 1212: Properties of each product. Id Name SBO M ahcys c S-Adenosyl-L-homocysteine M h c H+ M meroacidcyc2ACP c cyclopropanated alpha meroacid ACP (2 cyclopropane rings)

Kinetic Law

v647 = not speciﬁed (1294)

6.648 Reaction R MYC2CYC2 This is an irreversible reaction of two reactants forming three products.

Name Mycolic Acid Cyclopropanation

Reaction equation M amet c + M mmeroacidcyc1ACP c −→ M ahcys c + M h c + M mmeroacidcyc2ACP c (1295)

Reactants

Table 1213: Properties of each reactant. Id Name SBO M amet c S-Adenosyl-L-methionine M mmeroacidcyc1ACP c cyclopropanated methoxy-meroacid ACP (1 cyclopropane ring)

Products

Table 1214: Properties of each product. Id Name SBO M ahcys c S-Adenosyl-L-homocysteine M h c H+ M mmeroacidcyc2ACP c cyclopropanated methoxy-meroacid ACP (2 cyclopropane rings)

580 Produced by SBML2LATEX Kinetic Law

v648 = not speciﬁed (1296)

6.649 Reaction R MYC2CYC3 This is an irreversible reaction of two reactants forming three products.

Name Mycolic Acid Cyclopropanation

Reaction equation M amet c + M kmeroacidcyc1ACP c −→ M ahcys c + M h c + M kmeroacidcyc2ACP c (1297)

Reactants

Table 1215: Properties of each reactant. Id Name SBO M amet c S-Adenosyl-L-methionine M kmeroacidcyc1ACP c cyclopropanated keto-meroacid ACP (1 cyclopropane ring)

Products

Table 1216: Properties of each product. Id Name SBO M ahcys c S-Adenosyl-L-homocysteine M h c H+ M kmeroacidcyc2ACP c cyclopropanated keto-meroacid ACP (2 cyclopropane rings)

Kinetic Law

v649 = not speciﬁed (1298)

6.650 Reaction R MYCFLUX1

This is an irreversible reaction of one reactant forming one product.

Name mycolic acid conglomeration ﬂux

Produced by SBML2LATEX 581 Reaction equation M mycolate c −→ M rmyc c (1299)

Reactant

Table 1217: Properties of each reactant. Id Name SBO M mycolate c mycolate (2 cyclopropanated rings)

Product

Table 1218: Properties of each product. Id Name SBO M rmyc c mycolate compounds (all)

Kinetic Law

v650 = not speciﬁed (1300)

6.651 Reaction R MYCFLUX2 This is an irreversible reaction of one reactant forming one product.

Name mycolic acid conglomeration ﬂux

Reaction equation M mmycolate c −→ M rmyc c (1301)

Reactant

Table 1219: Properties of each reactant. Id Name SBO M mmycolate c methoxy mycolate (2 cyclopropanated rings)

Product

582 Produced by SBML2LATEX Table 1220: Properties of each product. Id Name SBO M rmyc c mycolate compounds (all)

Kinetic Law

v651 = not speciﬁed (1302)

6.652 Reaction R MYCFLUX3 This is an irreversible reaction of one reactant forming one product.

Name mycolic acid conglomeration ﬂux

Reaction equation M kmycolate c −→ M rmyc c (1303)

Reactant

Table 1221: Properties of each reactant. Id Name SBO M kmycolate c keto mycolate (2 cyclopropanated rings)

Product

Table 1222: Properties of each product. Id Name SBO M rmyc c mycolate compounds (all)

Kinetic Law

v652 = not speciﬁed (1304)

6.653 Reaction R MYCFLUX4 This is an irreversible reaction of one reactant forming one product.

Name mycolic acid conglomeration ﬂux

Produced by SBML2LATEX 583 Reaction equation M mmmycolate c −→ M rmyc c (1305)

Reactant

Table 1223: Properties of each reactant. Id Name SBO M mmmycolate c methoxy mycolate (1 cyclopropanated ring)

Product

Table 1224: Properties of each product. Id Name SBO M rmyc c mycolate compounds (all)

Kinetic Law

v653 = not speciﬁed (1306)

6.654 Reaction R MYCFLUX5 This is an irreversible reaction of one reactant forming one product.

Name mycolic acid conglomeration ﬂux

Reaction equation M mkmycolate c −→ M rmyc c (1307)

Reactant

Table 1225: Properties of each reactant. Id Name SBO M mkmycolate c keto mycolate (1 cyclopropanated rings)

Product

584 Produced by SBML2LATEX Table 1226: Properties of each product. Id Name SBO M rmyc c mycolate compounds (all)

Kinetic Law

v654 = not speciﬁed (1308)

6.655 Reaction R MYCON1 This is an irreversible reaction of three reactants forming ﬁve products.

Name Mycolic Acid Condensation

Reaction equation M chexccoa c + 2M h2o c + M meroacidcyc2AMP c −→ M amp c + M co2 c + M coa c + 2M h c + M mycolate c (1309)

Reactants

Table 1227: Properties of each reactant. Id Name SBO M chexccoa c carboxy hexacosanoyl-CoA M h2o c H2O M meroacidcyc2AMP c cyclopropanated alpha meroacid AMP (2 cyclopropane rings)

Products

Table 1228: Properties of each product. Id Name SBO M amp c AMP M co2 c CO2 M coa c Coenzyme A M h c H+ M mycolate c mycolate (2 cyclopropanated rings)

Produced by SBML2LATEX 585 Kinetic Law

v655 = not speciﬁed (1310)

6.656 Reaction R MYCON2 This is an irreversible reaction of three reactants forming ﬁve products.

Name Mycolic Acid Condensation

Reaction equation M chexccoa c + 2M h2o c + M mmeroacidcyc2AMP c −→ M amp c + M co2 c + M coa c + 2M h c + M mmycolate c (1311)

Reactants

Table 1229: Properties of each reactant. Id Name SBO M chexccoa c carboxy hexacosanoyl-CoA M h2o c H2O M mmeroacidcyc2AMP c cyclopropanated methoxy-meroacid AMP (2 cyclopropane rings)

Products

Table 1230: Properties of each product. Id Name SBO M amp c AMP M co2 c CO2 M coa c Coenzyme A M h c H+ M mmycolate c methoxy mycolate (2 cyclopropanated rings)

Kinetic Law

v656 = not speciﬁed (1312)

6.657 Reaction R MYCON3 This is an irreversible reaction of three reactants forming ﬁve products. Name Mycolic Acid Condensation

586 Produced by SBML2LATEX Reaction equation M chexccoa c + 2M h2o c + M kmeroacidcyc2AMP c −→ M amp c + M co2 c + M coa c + 2M h c + M kmycolate c (1313)

Reactants

Table 1231: Properties of each reactant. Id Name SBO M chexccoa c carboxy hexacosanoyl-CoA M h2o c H2O M kmeroacidcyc2AMP c cyclopropanated keto-meroacid AMP (2 cyclopropane rings)

Products

Table 1232: Properties of each product. Id Name SBO M amp c AMP M co2 c CO2 M coa c Coenzyme A M h c H+ M kmycolate c keto mycolate (2 cyclopropanated rings)

Kinetic Law

v657 = not speciﬁed (1314)

6.658 Reaction R MYCON4 This is an irreversible reaction of three reactants forming ﬁve products.

Name Mycolic Acid Condensation

Reaction equation M chexccoa c + 2M h2o c + M mmmeroacidcyc1AMP c −→ M amp c + M co2 c + M coa c + 2M h c + M mmmycolate c (1315)

Reactants

Produced by SBML2LATEX 587 Table 1233: Properties of each reactant. Id Name SBO M chexccoa c carboxy hexacosanoyl-CoA M h2o c H2O M mmmeroacidcyc1AMP c cyclopropanated methyl hydroxy methoxy meroacid AMP (1 cyclopropane ring)

Products

Table 1234: Properties of each product. Id Name SBO M amp c AMP M co2 c CO2 M coa c Coenzyme A M h c H+ M mmmycolate c methoxy mycolate (1 cyclopropanated ring)

Kinetic Law

v658 = not speciﬁed (1316)

6.659 Reaction R MYCON5 This is an irreversible reaction of three reactants forming ﬁve products.

Name Mycolic Acid Condensation

Reaction equation M chexccoa c + 2M h2o c + M mkmeroacidcyc1AMP c −→ M amp c + M co2 c + M coa c + 2M h c + M mkmycolate c (1317)

Reactants

Table 1235: Properties of each reactant. Id Name SBO M chexccoa c carboxy hexacosanoyl-CoA M h2o c H2O M mkmeroacidcyc1AMP c cyclopropanated methyl hydroxy keto meroacid AMP (1 cyclopropane ring)

588 Produced by SBML2LATEX Products

Table 1236: Properties of each product. Id Name SBO M amp c AMP M co2 c CO2 M coa c Coenzyme A M h c H+ M mkmycolate c keto mycolate (1 cyclopropanated rings)

Kinetic Law

v659 = not speciﬁed (1318)

6.660 Reaction R MYCSacp50 This is an irreversible reaction of four reactants forming ﬁve products.

Name mycolic acid synthase (C50)

Reaction equation 33M h c + M hexc c + 12M malACP c + 24M nadph c −→ 11M ACP c + 12M co2 c + 13M h2o c + M meroacidACP c + 24M nadp c (1319)

Reactants

Table 1237: Properties of each reactant. Id Name SBO M h c H+ M hexc c hexacosanoate (n-C26:0) M malACP c Malonyl-[acyl-carrier protein] M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

Products

Table 1238: Properties of each product. Id Name SBO M ACP c acyl carrier protein

Produced by SBML2LATEX 589 Id Name SBO M co2 c CO2 M h2o c H2O M meroacidACP c alpha meroacid ACP M nadp c Nicotinamide adenine dinucleotide phosphate

Kinetic Law

v660 = not speciﬁed (1320)

6.661 Reaction R MYCSacp56 This is an irreversible reaction of four reactants forming ﬁve products.

Name mycolic acid synthase (C56)

Reaction equation 42M h c + M hexc c + 15M malACP c + 30M nadph c −→ 14M ACP c + 15M co2 c + 16M h2o c + M mmeroacidACP c + 30M nadp c (1321)

Reactants

Table 1239: Properties of each reactant. Id Name SBO M h c H+ M hexc c hexacosanoate (n-C26:0) M malACP c Malonyl-[acyl-carrier protein] M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

Products

Table 1240: Properties of each product. Id Name SBO M ACP c acyl carrier protein M co2 c CO2 M h2o c H2O M mmeroacidACP c methoxy meroacid ACP M nadp c Nicotinamide adenine dinucleotide phosphate

590 Produced by SBML2LATEX Kinetic Law

v661 = not speciﬁed (1322)

6.662 Reaction R MYCSacp58 This is an irreversible reaction of four reactants forming ﬁve products.

Name mycolic acid synthase (C58)

Reaction equation 47M h c + M hexc c + 16M malACP c + 30M nadph c −→ 15M ACP c + 16M co2 c + 17M h2o c + M kmeroacidACP c + 30M nadp c (1323)

Reactants

Table 1241: Properties of each reactant. Id Name SBO M h c H+ M hexc c hexacosanoate (n-C26:0) M malACP c Malonyl-[acyl-carrier protein] M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

Products

Table 1242: Properties of each product. Id Name SBO M ACP c acyl carrier protein M co2 c CO2 M h2o c H2O M kmeroacidACP c keto meroacid ACP M nadp c Nicotinamide adenine dinucleotide phosphate

Kinetic Law

v662 = not speciﬁed (1324)

6.663 Reaction R MYCTR This is a reversible reaction of two reactants forming three products.

Produced by SBML2LATEX 591 Name mycothiol reductase (nadp dependent)

Reaction equation 2M msh c + M nadp c )−−−−* M h c + M mssg c + M nadph c (1325)

Reactants

Table 1243: Properties of each reactant. Id Name SBO M msh c mycothiol (reduced) M nadp c Nicotinamide adenine dinucleotide phosphate

Products

Table 1244: Properties of each product. Id Name SBO M h c H+ M mssg c mycothiol (oxidized - dimer) M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

Kinetic Law

v663 = not speciﬁed (1326)

6.664 Reaction R MYCTR2 This is a reversible reaction of two reactants forming two products.

Name mycothiol reductase (glutathione exchange)

Reaction equation M gthox c + 2M msh c )−−−−* 2M gthrd c + M mssg c (1327)

Reactants

592 Produced by SBML2LATEX Table 1245: Properties of each reactant. Id Name SBO M gthox c Oxidized glutathione M msh c mycothiol (reduced)

Products

Table 1246: Properties of each product. Id Name SBO M gthrd c Reduced glutathione M mssg c mycothiol (oxidized - dimer)

Kinetic Law

v664 = not speciﬁed (1328)

6.665 Reaction R NADH10 This is an irreversible reaction of three reactants forming two products.

Name NADH dehydrogenase (menaquinone-8 & 0 protons)

Reaction equation M h c + M mqn8 c + M nadh c −→ M mql8 c + M nad c (1329)

Reactants

Table 1247: Properties of each reactant. Id Name SBO M h c H+ M mqn8 c Menaquinone 8 M nadh c Nicotinamide adenine dinucleotide - reduced

Products

Produced by SBML2LATEX 593 Table 1248: Properties of each product. Id Name SBO M mql8 c Menaquinol 8 M nad c Nicotinamide adenine dinucleotide

Kinetic Law

v665 = not speciﬁed (1330)

6.666 Reaction R NADH2r This is a reversible reaction of three reactants forming two products.

Name NADH dehydrogenase

Reaction equation M h c + M nadh c + M q c )−−−−* M nad c + M qh2 c (1331)

Reactants

Table 1249: Properties of each reactant. Id Name SBO M h c H+ M nadh c Nicotinamide adenine dinucleotide - reduced M q c Ubiquinone

Products

Table 1250: Properties of each product. Id Name SBO M nad c Nicotinamide adenine dinucleotide M qh2 c Ubiquinol

Kinetic Law

v666 = not speciﬁed (1332)

594 Produced by SBML2LATEX 6.667 Reaction R NADH5 This is an irreversible reaction of three reactants forming two products.

Name NADH dehydrogenase (ubiquinone-8 )

Reaction equation M h c + M nadh c + M q8 c −→ M nad c + M q8h2 c (1333)

Reactants

Table 1251: Properties of each reactant. Id Name SBO M h c H+ M nadh c Nicotinamide adenine dinucleotide - reduced M q8 c Ubiquinone-8

Products

Table 1252: Properties of each product. Id Name SBO M nad c Nicotinamide adenine dinucleotide M q8h2 c Ubiquinol-8

Kinetic Law

v667 = not speciﬁed (1334)

6.668 Reaction R NADH9 This is an irreversible reaction of three reactants forming two products.

Name NADH dehydrogenase (demethylmenaquinone-8 & 0 protons)

Reaction equation M 2dmmq8 c + M h c + M nadh c −→ M 2dmmql8 c + M nad c (1335)

Reactants

Produced by SBML2LATEX 595 Table 1253: Properties of each reactant. Id Name SBO M 2dmmq8 c 2-Demethylmenaquinone 8 M h c H+ M nadh c Nicotinamide adenine dinucleotide - reduced

Products

Table 1254: Properties of each product. Id Name SBO M 2dmmql8 c 2-Demethylmenaquinol 8 M nad c Nicotinamide adenine dinucleotide

Kinetic Law

v668 = not speciﬁed (1336)

6.669 Reaction R NADK This is an irreversible reaction of two reactants forming three products.

Name NAD kinase

Reaction equation M atp c + M nad c −→ M adp c + M h c + M nadp c (1337)

Reactants

Table 1255: Properties of each reactant. Id Name SBO M atp c ATP M nad c Nicotinamide adenine dinucleotide

Products

596 Produced by SBML2LATEX Table 1256: Properties of each product. Id Name SBO M adp c ADP M h c H+ M nadp c Nicotinamide adenine dinucleotide phosphate

Kinetic Law

v669 = not speciﬁed (1338)

6.670 Reaction R NADS2 This is an irreversible reaction of four reactants forming ﬁve products.

Name NAD synthase (glutamine-hydrolysing)

Reaction equation M atp c + M dnad c + M gln DASH L c + M h2o c −→ M amp c + M glu DASH L c + M h c + M nad c + M ppi c (1339)

Reactants

Table 1257: Properties of each reactant. Id Name SBO M atp c ATP M dnad c Deamino-NAD+ M gln DASH L c L-Glutamine M h2o c H2O

Products

Table 1258: Properties of each product. Id Name SBO M amp c AMP M glu DASH L c L-Glutamate M h c H+ M nad c Nicotinamide adenine dinucleotide M ppi c Diphosphate

Produced by SBML2LATEX 597 Kinetic Law

v670 = not speciﬁed (1340)

6.671 Reaction R NADTRHD This is an irreversible reaction of two reactants forming two products.

Name NAD transhydrogenase

Reaction equation M nad c + M nadph c −→ M nadh c + M nadp c (1341)

Reactants

Table 1259: Properties of each reactant. Id Name SBO M nad c Nicotinamide adenine dinucleotide M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

Products

Table 1260: Properties of each product. Id Name SBO M nadh c Nicotinamide adenine dinucleotide - reduced M nadp c Nicotinamide adenine dinucleotide phosphate

Kinetic Law

v671 = not speciﬁed (1342)

6.672 Reaction R NAKtr This is a reversible reaction of two reactants forming two products.

Name potassium sodium antiporter

Reaction equation

M k c + M na1 e )−−−−* M k e + M na1 c (1343)

598 Produced by SBML2LATEX Reactants

Table 1261: Properties of each reactant. Id Name SBO M k c potassium M na1 e Sodium

Products

Table 1262: Properties of each product. Id Name SBO M k e potassium M na1 c Sodium

Kinetic Law

v672 = not speciﬁed (1344)

6.673 Reaction R NAPRTr This is a reversible reaction of three reactants forming two products.

Name NAPRTase (rev)

Reaction equation M h c + M nac c + M prpp c )−−−−* M nicrnt c + M ppi c (1345)

Reactants

Table 1263: Properties of each reactant. Id Name SBO M h c H+ M nac c Nicotinate M prpp c 5-Phospho-alpha-D-ribose 1-diphosphate

Products

Produced by SBML2LATEX 599 Table 1264: Properties of each product. Id Name SBO M nicrnt c Nicotinate D-ribonucleotide M ppi c Diphosphate

Kinetic Law

v673 = not speciﬁed (1346)

6.674 Reaction R NARK This is an irreversible reaction of one reactant forming one product.

Name nark

Reaction equation M no2 c −→ M no2 e (1347)

Reactant

Table 1265: Properties of each reactant. Id Name SBO M no2 c Nitrite

Product

Table 1266: Properties of each product. Id Name SBO M no2 e Nitrite

Kinetic Law

v674 = not speciﬁed (1348)

6.675 Reaction R NAt3 1 This is a reversible reaction of two reactants forming two products.

Name sodium proton antiporter (H:NA is 1:1)

600 Produced by SBML2LATEX Reaction equation M h e + M na1 c )−−−−* M h c + M na1 e (1349)

Reactants

Table 1267: Properties of each reactant. Id Name SBO M h e H+ M na1 c Sodium

Products

Table 1268: Properties of each product. Id Name SBO M h c H+ M na1 e Sodium

Kinetic Law

v675 = not speciﬁed (1350)

6.676 Reaction R NDPK1 This is a reversible reaction of two reactants forming two products.

Name nucleoside-diphosphate kinase (ATP:GDP)

Reaction equation M atp c + M gdp c )−−−−* M adp c + M gtp c (1351)

Reactants

Table 1269: Properties of each reactant. Id Name SBO M atp c ATP M gdp c GDP

Produced by SBML2LATEX 601 Products

Table 1270: Properties of each product. Id Name SBO M adp c ADP M gtp c GTP

Kinetic Law

v676 = not speciﬁed (1352)

6.677 Reaction R NDPK2 This is a reversible reaction of two reactants forming two products.

Name nucleoside-diphosphate kinase (ATP:UDP)

Reaction equation M atp c + M udp c )−−−−* M adp c + M utp c (1353)

Reactants

Table 1271: Properties of each reactant. Id Name SBO M atp c ATP M udp c UDP

Products

Table 1272: Properties of each product. Id Name SBO M adp c ADP M utp c UTP

Kinetic Law

v677 = not speciﬁed (1354)

602 Produced by SBML2LATEX 6.678 Reaction R NDPK3 This is a reversible reaction of two reactants forming two products.

Name nucleoside-diphosphate kinase (ATP:CDP)

Reaction equation M atp c + M cdp c )−−−−* M adp c + M ctp c (1355)

Reactants

Table 1273: Properties of each reactant. Id Name SBO M atp c ATP M cdp c CDP

Products

Table 1274: Properties of each product. Id Name SBO M adp c ADP M ctp c CTP

Kinetic Law

v678 = not speciﬁed (1356)

6.679 Reaction R NDPK4 This is a reversible reaction of two reactants forming two products.

Name nucleoside-diphosphate kinase (ATP:dTDP)

Reaction equation M atp c + M dtdp c )−−−−* M adp c + M dttp c (1357)

Reactants

Produced by SBML2LATEX 603 Table 1275: Properties of each reactant. Id Name SBO M atp c ATP M dtdp c dTDP

Products

Table 1276: Properties of each product. Id Name SBO M adp c ADP M dttp c dTTP

Kinetic Law

v679 = not speciﬁed (1358)

6.680 Reaction R NDPK5 This is a reversible reaction of two reactants forming two products.

Name nucleoside-diphosphate kinase (ATP:dGDP)

Reaction equation M atp c + M dgdp c )−−−−* M adp c + M dgtp c (1359)

Reactants

Table 1277: Properties of each reactant. Id Name SBO M atp c ATP M dgdp c dGDP

Products

Table 1278: Properties of each product. Id Name SBO M adp c ADP

604 Produced by SBML2LATEX Id Name SBO M dgtp c dGTP

Kinetic Law

v680 = not speciﬁed (1360)

6.681 Reaction R NDPK6 This is a reversible reaction of two reactants forming two products.

Name nucleoside-diphosphate kinase (ATP:dUDP)

Reaction equation M atp c + M dudp c )−−−−* M adp c + M dutp c (1361)

Reactants

Table 1279: Properties of each reactant. Id Name SBO M atp c ATP M dudp c dUDP

Products

Table 1280: Properties of each product. Id Name SBO M adp c ADP M dutp c dUTP

Kinetic Law

v681 = not speciﬁed (1362)

6.682 Reaction R NDPK7 This is a reversible reaction of two reactants forming two products.

Name nucleoside-diphosphate kinase (ATP:dCDP)

Produced by SBML2LATEX 605 Reaction equation M atp c + M dcdp c )−−−−* M adp c + M dctp c (1363)

Reactants

Table 1281: Properties of each reactant. Id Name SBO M atp c ATP M dcdp c dCDP

Products

Table 1282: Properties of each product. Id Name SBO M adp c ADP M dctp c dCTP

Kinetic Law

v682 = not speciﬁed (1364)

6.683 Reaction R NDPK8 This is a reversible reaction of two reactants forming two products.

Name nucleoside-diphosphate kinase (ATP:dADP)

Reaction equation M atp c + M dadp c )−−−−* M adp c + M datp c (1365)

Reactants

Table 1283: Properties of each reactant. Id Name SBO M atp c ATP M dadp c dADP

606 Produced by SBML2LATEX Products

Table 1284: Properties of each product. Id Name SBO M adp c ADP M datp c dATP

Kinetic Law

v683 = not speciﬁed (1366)

6.684 Reaction R NDPK9 This is a reversible reaction of two reactants forming two products.

Name nucleoside-diphosphate kinase (ATP:IDP)

Reaction equation M atp c + M idp c )−−−−* M adp c + M itp c (1367)

Reactants

Table 1285: Properties of each reactant. Id Name SBO M atp c ATP M idp c IDP

Products

Table 1286: Properties of each product. Id Name SBO M adp c ADP M itp c ITP

Kinetic Law

v684 = not speciﬁed (1368)

Produced by SBML2LATEX 607 6.685 Reaction R NH4OHDs This is a reversible reaction of two reactants forming two products.

Name NH4OH dissociation

Reaction equation M h c + M nh4oh c )−−−−* M h2o c + M nh4 c (1369)

Reactants

Table 1287: Properties of each reactant. Id Name SBO M h c H+ M nh4oh c Ammonium hydroxide

Products

Table 1288: Properties of each product. Id Name SBO M h2o c H2O M nh4 c Ammonium

Kinetic Law

v685 = not speciﬁed (1370)

6.686 Reaction R NH4t This is a reversible reaction of one reactant forming one product.

Name ammonia reversible transport

Reaction equation M nh4 e )−−−−* M nh4 c (1371)

Reactant

608 Produced by SBML2LATEX Table 1289: Properties of each reactant. Id Name SBO M nh4 e Ammonium

Product

Table 1290: Properties of each product. Id Name SBO M nh4 c Ammonium

Kinetic Law

v686 = not speciﬁed (1372)

6.687 Reaction R NNAM This is an irreversible reaction of two reactants forming two products.

Name nicotinamidase

Reaction equation M h2o c + M ncam c −→ M nac c + M nh4 c (1373)

Reactants

Table 1291: Properties of each reactant. Id Name SBO M h2o c H2O M ncam c Nicotinamide

Products

Table 1292: Properties of each product. Id Name SBO M nac c Nicotinate M nh4 c Ammonium

Produced by SBML2LATEX 609 Kinetic Law

v687 = not speciﬁed (1374)

6.688 Reaction R NNAT This is an irreversible reaction of three reactants forming two products.

Name nicotinate-nucleotide adenylyltransferase

Reaction equation M atp c + M h c + M nicrnt c −→ M dnad c + M ppi c (1375)

Reactants

Table 1293: Properties of each reactant. Id Name SBO M atp c ATP M h c H+ M nicrnt c Nicotinate D-ribonucleotide

Products

Table 1294: Properties of each product. Id Name SBO M dnad c Deamino-NAD+ M ppi c Diphosphate

Kinetic Law

v688 = not speciﬁed (1376)

6.689 Reaction R NNDMBRT This is an irreversible reaction of two reactants forming three products.

Name Nicotinate-nucleotide dimethylbenzimidazole phosphoribosyltransferase

Reaction equation M dmbzid c + M nicrnt c −→ M 5prdmbz c + M h c + M nac c (1377)

610 Produced by SBML2LATEX Reactants

Table 1295: Properties of each reactant. Id Name SBO M dmbzid c 5,6-Dimethylbenzimidazole M nicrnt c Nicotinate D-ribonucleotide

Products

Table 1296: Properties of each product. Id Name SBO M 5prdmbz c N1-(5-Phospho-alpha-D-ribosyl)-5,6-dimethylbenzimidazole M h c H+ M nac c Nicotinate

Kinetic Law

v689 = not speciﬁed (1378)

6.690 Reaction R NNDPR This is an irreversible reaction of three reactants forming three products.

Name nicotinate-nucleotide diphosphorylase (carboxylating)

Reaction equation 2M h c + M prpp c + M quln c −→ M co2 c + M nicrnt c + M ppi c (1379)

Reactants

Table 1297: Properties of each reactant. Id Name SBO M h c H+ M prpp c 5-Phospho-alpha-D-ribose 1-diphosphate M quln c Quinolinate

Products

Produced by SBML2LATEX 611 Table 1298: Properties of each product. Id Name SBO M co2 c CO2 M nicrnt c Nicotinate D-ribonucleotide M ppi c Diphosphate

Kinetic Law

v690 = not speciﬁed (1380)

6.691 Reaction R NO This is an irreversible reaction of two reactants forming one product.

Name peroxynitrite formation (spontanous)

Reaction equation M no c + M o2s c −→ M no3 c (1381)

Reactants

Table 1299: Properties of each reactant. Id Name SBO M no c Nitric oxide M o2s c Superoxide anion

Product

Table 1300: Properties of each product. Id Name SBO M no3 c Nitrate

Kinetic Law

v691 = not speciﬁed (1382)

6.692 Reaction R NO3R1 This is an irreversible reaction of three reactants forming four products.

612 Produced by SBML2LATEX Name Nitrate reductase (Ubiquinol-8)

Reaction equation 2M h c + M no3 c + M q8h2 c −→ M h2o c + 2M h e + M no2 c + M q8 c (1383)

Reactants

Table 1301: Properties of each reactant. Id Name SBO M h c H+ M no3 c Nitrate M q8h2 c Ubiquinol-8

Products

Table 1302: Properties of each product. Id Name SBO M h2o c H2O M h e H+ M no2 c Nitrite M q8 c Ubiquinone-8

Kinetic Law

v692 = not speciﬁed (1384)

6.693 Reaction R NO3R2 This is an irreversible reaction of three reactants forming four products.

Name Nitrate reductase (Menaquinol-8)

Reaction equation 2M h c + M mql8 c + M no3 c −→ M h2o c + 2M h e + M mqn8 c + M no2 c (1385)

Reactants

Produced by SBML2LATEX 613 Table 1303: Properties of each reactant. Id Name SBO M h c H+ M mql8 c Menaquinol 8 M no3 c Nitrate

Products

Table 1304: Properties of each product. Id Name SBO M h2o c H2O M h e H+ M mqn8 c Menaquinone 8 M no2 c Nitrite

Kinetic Law

v693 = not speciﬁed (1386)

6.694 Reaction R NO3t7 This is an irreversible reaction of two reactants forming two products.

Name nitrate transport in via nitrite antiport

Reaction equation M no2 c + M no3 e −→ M no2 e + M no3 c (1387)

Reactants

Table 1305: Properties of each reactant. Id Name SBO M no2 c Nitrite M no3 e Nitrate

Products

614 Produced by SBML2LATEX Table 1306: Properties of each product. Id Name SBO M no2 e Nitrite M no3 c Nitrate

Kinetic Law

v694 = not speciﬁed (1388)

6.695 Reaction R NOt This is a reversible reaction of one reactant forming one product.

Name NO transport (diffusion)

Reaction equation M no e )−−−−* M no c (1389)

Reactant

Table 1307: Properties of each reactant. Id Name SBO M no e Nitric oxide

Product

Table 1308: Properties of each product. Id Name SBO M no c Nitric oxide

Kinetic Law

v695 = not speciﬁed (1390)

6.696 Reaction R NPHS This is an irreversible reaction of one reactant forming two products.

Name naphthoate synthase

Produced by SBML2LATEX 615 Reaction equation M sbzcoa c −→ M coa c + M dhna c (1391)

Reactant

Table 1309: Properties of each reactant. Id Name SBO M sbzcoa c O-Succinylbenzoyl-CoA

Products

Table 1310: Properties of each product. Id Name SBO M coa c Coenzyme A M dhna c 1,4-Dihydroxy-2-naphthoate

Kinetic Law

v696 = not speciﬁed (1392)

6.697 Reaction R NTD1 This is an irreversible reaction of two reactants forming two products.

Name 5’-nucleotidase (dUMP)

Reaction equation M dump c + M h2o c −→ M duri c + M pi c (1393)

Reactants

Table 1311: Properties of each reactant. Id Name SBO M dump c dUMP M h2o c H2O

616 Produced by SBML2LATEX Products

Table 1312: Properties of each product. Id Name SBO M duri c Deoxyuridine M pi c Phosphate

Kinetic Law

v697 = not speciﬁed (1394)

6.698 Reaction R NTD10 This is an irreversible reaction of two reactants forming two products.

Name 5’-nucleotidase (XMP)

Reaction equation M h2o c + M xmp c −→ M pi c + M xtsn c (1395)

Reactants

Table 1313: Properties of each reactant. Id Name SBO M h2o c H2O M xmp c Xanthosine 5’-phosphate

Products

Table 1314: Properties of each product. Id Name SBO M pi c Phosphate M xtsn c Xanthosine

Kinetic Law

v698 = not speciﬁed (1396)

Produced by SBML2LATEX 617 6.699 Reaction R NTD11 This is an irreversible reaction of two reactants forming two products.

Name 5’-nucleotidase (IMP)

Reaction equation M h2o c + M imp c −→ M ins c + M pi c (1397)

Reactants

Table 1315: Properties of each reactant. Id Name SBO M h2o c H2O M imp c IMP

Products

Table 1316: Properties of each product. Id Name SBO M ins c Inosine M pi c Phosphate

Kinetic Law

v699 = not speciﬁed (1398)

6.700 Reaction R NTD2 This is an irreversible reaction of two reactants forming two products.

Name 5’-nucleotidase (UMP)

Reaction equation M h2o c + M ump c −→ M pi c + M uri c (1399)

Reactants

618 Produced by SBML2LATEX Table 1317: Properties of each reactant. Id Name SBO M h2o c H2O M ump c UMP

Products

Table 1318: Properties of each product. Id Name SBO M pi c Phosphate M uri c Uridine

Kinetic Law

v700 = not speciﬁed (1400)

6.701 Reaction R NTD3 This is an irreversible reaction of two reactants forming two products.

Name 5’-nucleotidase (dCMP)

Reaction equation M dcmp c + M h2o c −→ M dcyt c + M pi c (1401)

Reactants

Table 1319: Properties of each reactant. Id Name SBO M dcmp c dCMP M h2o c H2O

Products

Table 1320: Properties of each product. Id Name SBO M dcyt c Deoxycytidine

Produced by SBML2LATEX 619 Id Name SBO M pi c Phosphate

Kinetic Law

v701 = not speciﬁed (1402)

6.702 Reaction R NTD4 This is an irreversible reaction of two reactants forming two products.

Name 5’-nucleotidase (CMP)

Reaction equation M cmp c + M h2o c −→ M cytd c + M pi c (1403)

Reactants

Table 1321: Properties of each reactant. Id Name SBO M cmp c CMP M h2o c H2O

Products

Table 1322: Properties of each product. Id Name SBO M cytd c Cytidine M pi c Phosphate

Kinetic Law

v702 = not speciﬁed (1404)

6.703 Reaction R NTD5 This is an irreversible reaction of two reactants forming two products.

Name 5’-nucleotidase (dTMP)

620 Produced by SBML2LATEX Reaction equation M dtmp c + M h2o c −→ M pi c + M thymd c (1405)

Reactants

Table 1323: Properties of each reactant. Id Name SBO M dtmp c dTMP M h2o c H2O

Products

Table 1324: Properties of each product. Id Name SBO M pi c Phosphate M thymd c Thymidine

Kinetic Law

v703 = not speciﬁed (1406)

6.704 Reaction R NTD6 This is an irreversible reaction of two reactants forming two products.

Name 5’-nucleotidase (dAMP)

Reaction equation M damp c + M h2o c −→ M dad DASH 2 c + M pi c (1407)

Reactants

Table 1325: Properties of each reactant. Id Name SBO M damp c dAMP M h2o c H2O

Produced by SBML2LATEX 621 Products

Table 1326: Properties of each product. Id Name SBO M dad DASH 2 c Deoxyadenosine M pi c Phosphate

Kinetic Law

v704 = not speciﬁed (1408)

6.705 Reaction R NTD7 This is an irreversible reaction of two reactants forming two products.

Name 5’-nucleotidase (AMP)

Reaction equation M amp c + M h2o c −→ M adn c + M pi c (1409)

Reactants

Table 1327: Properties of each reactant. Id Name SBO M amp c AMP M h2o c H2O

Products

Table 1328: Properties of each product. Id Name SBO M adn c Adenosine M pi c Phosphate

Kinetic Law

v705 = not speciﬁed (1410)

622 Produced by SBML2LATEX 6.706 Reaction R NTD8 This is an irreversible reaction of two reactants forming two products.

Name 5’-nucleotidase (dGMP)

Reaction equation M dgmp c + M h2o c −→ M dgsn c + M pi c (1411)

Reactants

Table 1329: Properties of each reactant. Id Name SBO M dgmp c dGMP M h2o c H2O

Products

Table 1330: Properties of each product. Id Name SBO M dgsn c Deoxyguanosine M pi c Phosphate

Kinetic Law

v706 = not speciﬁed (1412)

6.707 Reaction R NTD9 This is an irreversible reaction of two reactants forming two products.

Name 5’-nucleotidase (GMP)

Reaction equation M gmp c + M h2o c −→ M gsn c + M pi c (1413)

Reactants

Produced by SBML2LATEX 623 Table 1331: Properties of each reactant. Id Name SBO M gmp c GMP M h2o c H2O

Products

Table 1332: Properties of each product. Id Name SBO M gsn c Guanosine M pi c Phosphate

Kinetic Law

v707 = not speciﬁed (1414)

6.708 Reaction R NTPP2 This is an irreversible reaction of two reactants forming three products.

Name Nucleoside triphosphate pyrophosphorylase (gtp)

Reaction equation M gtp c + M h2o c −→ M gmp c + M h c + M ppi c (1415)

Reactants

Table 1333: Properties of each reactant. Id Name SBO M gtp c GTP M h2o c H2O

Products

Table 1334: Properties of each product. Id Name SBO M gmp c GMP

624 Produced by SBML2LATEX Id Name SBO M h c H+ M ppi c Diphosphate

Kinetic Law

v708 = not speciﬁed (1416)

6.709 Reaction R NTPP3 This is an irreversible reaction of two reactants forming three products.

Name Nucleoside triphosphate pyrophosphorylase (dctp)

Reaction equation M dctp c + M h2o c −→ M dcmp c + M h c + M ppi c (1417)

Reactants

Table 1335: Properties of each reactant. Id Name SBO M dctp c dCTP M h2o c H2O

Products

Table 1336: Properties of each product. Id Name SBO M dcmp c dCMP M h c H+ M ppi c Diphosphate

Kinetic Law

v709 = not speciﬁed (1418)

6.710 Reaction R NTPP4 This is an irreversible reaction of two reactants forming three products.

Produced by SBML2LATEX 625 Name Nucleoside triphosphate pyrophosphorylase (ctp)

Reaction equation M ctp c + M h2o c −→ M cmp c + M h c + M ppi c (1419)

Reactants

Table 1337: Properties of each reactant. Id Name SBO M ctp c CTP M h2o c H2O

Products

Table 1338: Properties of each product. Id Name SBO M cmp c CMP M h c H+ M ppi c Diphosphate

Kinetic Law

v710 = not speciﬁed (1420)

6.711 Reaction R NTPP5 This is an irreversible reaction of two reactants forming three products.

Name Nucleoside triphosphate pyrophosphorylase (datp)

Reaction equation M datp c + M h2o c −→ M damp c + M h c + M ppi c (1421)

Reactants

626 Produced by SBML2LATEX Table 1339: Properties of each reactant. Id Name SBO M datp c dATP M h2o c H2O

Products

Table 1340: Properties of each product. Id Name SBO M damp c dAMP M h c H+ M ppi c Diphosphate

Kinetic Law

v711 = not speciﬁed (1422)

6.712 Reaction R NTPP7 This is an irreversible reaction of two reactants forming three products.

Name Nucleoside triphosphate pyrophosphorylase (dttp)

Reaction equation M dttp c + M h2o c −→ M dtmp c + M h c + M ppi c (1423)

Reactants

Table 1341: Properties of each reactant. Id Name SBO M dttp c dTTP M h2o c H2O

Products

Produced by SBML2LATEX 627 Table 1342: Properties of each product. Id Name SBO M dtmp c dTMP M h c H+ M ppi c Diphosphate

Kinetic Law

v712 = not speciﬁed (1424)

6.713 Reaction R NTPP8 This is an irreversible reaction of two reactants forming three products.

Name Nucleoside triphosphate pyrophosphorylase (utp)

Reaction equation M h2o c + M utp c −→ M h c + M ppi c + M ump c (1425)

Reactants

Table 1343: Properties of each reactant. Id Name SBO M h2o c H2O M utp c UTP

Products

Table 1344: Properties of each product. Id Name SBO M h c H+ M ppi c Diphosphate M ump c UMP

Kinetic Law

v713 = not speciﬁed (1426)

628 Produced by SBML2LATEX 6.714 Reaction R NTPTP1 This is an irreversible reaction of two reactants forming two products.

Name Nucleoside triphosphate tripolyhydrolase

Reaction equation M dgtp c + M h2o c −→ M dgsn c + M pppi c (1427)

Reactants

Table 1345: Properties of each reactant. Id Name SBO M dgtp c dGTP M h2o c H2O

Products

Table 1346: Properties of each product. Id Name SBO M dgsn c Deoxyguanosine M pppi c Inorganic triphosphate

Kinetic Law

v714 = not speciﬁed (1428)

6.715 Reaction R NTPTP2 This is an irreversible reaction of two reactants forming two products.

Name Nucleoside triphosphate tripolyhydrolase

Reaction equation M gtp c + M h2o c −→ M gsn c + M pppi c (1429)

Reactants

Produced by SBML2LATEX 629 Table 1347: Properties of each reactant. Id Name SBO M gtp c GTP M h2o c H2O

Products

Table 1348: Properties of each product. Id Name SBO M gsn c Guanosine M pppi c Inorganic triphosphate

Kinetic Law

v715 = not speciﬁed (1430)

6.716 Reaction R NTRIR2x This is an irreversible reaction of three reactants forming three products.

Name nitrite Reductase (NADH)

Reaction equation 5M h c + 3M nadh c + M no2 c −→ 2M h2o c + 3M nad c + M nh4 c (1431)

Reactants

Table 1349: Properties of each reactant. Id Name SBO M h c H+ M nadh c Nicotinamide adenine dinucleotide - reduced M no2 c Nitrite

Products

630 Produced by SBML2LATEX Table 1350: Properties of each product. Id Name SBO M h2o c H2O M nad c Nicotinamide adenine dinucleotide M nh4 c Ammonium

Kinetic Law

v716 = not speciﬁed (1432)

6.717 Reaction R NTRIRx This is an irreversible reaction of three reactants forming three products.

Name nitrite reductase (NADH)

Reaction equation 4M h c + 3M nadh c + M no2 c −→ M h2o c + 3M nad c + M nh4oh c (1433)

Reactants

Table 1351: Properties of each reactant. Id Name SBO M h c H+ M nadh c Nicotinamide adenine dinucleotide - reduced M no2 c Nitrite

Products

Table 1352: Properties of each product. Id Name SBO M h2o c H2O M nad c Nicotinamide adenine dinucleotide M nh4oh c Ammonium hydroxide

Kinetic Law

v717 = not speciﬁed (1434)

Produced by SBML2LATEX 631 6.718 Reaction R NTRIRy This is an irreversible reaction of three reactants forming three products.

Name nitrite reductase (NADPH)

Reaction equation 4M h c + 3M nadph c + M no2 c −→ M h2o c + 3M nadp c + M nh4oh c (1435)

Reactants

Table 1353: Properties of each reactant. Id Name SBO M h c H+ M nadph c Nicotinamide adenine dinucleotide phosphate - reduced M no2 c Nitrite

Products

Table 1354: Properties of each product. Id Name SBO M h2o c H2O M nadp c Nicotinamide adenine dinucleotide phosphate M nh4oh c Ammonium hydroxide

Kinetic Law

v718 = not speciﬁed (1436)

6.719 Reaction R O16RHAT This is an irreversible reaction of two reactants forming three products.

Name rhamnosyltransferase (LPS O16 antigen biosynthesis)

Reaction equation M dtdprmn c + M unaga c −→ M dtdp c + M h c + M ragund c (1437)

Reactants

632 Produced by SBML2LATEX Table 1355: Properties of each reactant. Id Name SBO M dtdprmn c dTDP-L-rhamnose M unaga c Undecaprenyl diphospho N-acetyl-glucosamine

Products

Table 1356: Properties of each product. Id Name SBO M dtdp c dTDP M h c H+ M ragund c rhamanosyl-N-acetylglucosamyl-undecaprenyl diphosphate

Kinetic Law

v719 = not speciﬁed (1438)

6.720 Reaction R O2t This is a reversible reaction of one reactant forming one product.

Name o2 transport (diffusion)

Reaction equation M o2 e )−−−−* M o2 c (1439)

Reactant

Table 1357: Properties of each reactant. Id Name SBO M o2 e O2

Product

Table 1358: Properties of each product. Id Name SBO M o2 c O2

Produced by SBML2LATEX 633 Id Name SBO

Kinetic Law

v720 = not speciﬁed (1440)

6.721 Reaction R OCBT This is a reversible reaction of two reactants forming three products.

Name ornithine carbamoyltransferase

Reaction equation M cbp c + M orn c −−)−−* M citr DASH L c + M h c + M pi c (1441)

Reactants

Table 1359: Properties of each reactant. Id Name SBO M cbp c Carbamoyl phosphate M orn c Ornithine

Products

Table 1360: Properties of each product. Id Name SBO M citr DASH L c L-Citrulline M h c H+ M pi c Phosphate

Kinetic Law

v721 = not speciﬁed (1442)

6.722 Reaction R OCDCAt2 This is an irreversible reaction of two reactants forming two products.

Name Octadecanoate transport via proton symport

634 Produced by SBML2LATEX Reaction equation M h e + M ocdca e −→ M h c + M ocdca c (1443)

Reactants

Table 1361: Properties of each reactant. Id Name SBO M h e H+ M ocdca e octadecanoate (n-C18:0)

Products

Table 1362: Properties of each product. Id Name SBO M h c H+ M ocdca c octadecanoate (n-C18:0)

Kinetic Law

v722 = not speciﬁed (1444)

6.723 Reaction R OCOAT1r This is a reversible reaction of two reactants forming two products.

Name 3-oxoacid CoA-transferase (Succinyl-CoA: acetoacetate)

Reaction equation M acac c + M succoa c )−−−−* M aacoa c + M succ c (1445)

Reactants

Table 1363: Properties of each reactant. Id Name SBO M acac c Acetoacetate M succoa c Succinyl-CoA

Produced by SBML2LATEX 635 Products

Table 1364: Properties of each product. Id Name SBO M aacoa c Acetoacetyl-CoA M succ c Succinate

Kinetic Law

v723 = not speciﬁed (1446)

6.724 Reaction R OCTDPS This is an irreversible reaction of two reactants forming two products.

Name Octaprenyl pyrophosphate synthase

Reaction equation M frdp c + 5M ipdp c −→ M octdp c + 5M ppi c (1447)

Reactants

Table 1365: Properties of each reactant. Id Name SBO M frdp c Farnesyl diphosphate M ipdp c Isopentenyl diphosphate

Products

Table 1366: Properties of each product. Id Name SBO M octdp c all-trans-Octaprenyl diphosphate M ppi c Diphosphate

Kinetic Law

v724 = not speciﬁed (1448)

636 Produced by SBML2LATEX 6.725 Reaction R OHPBAT This is a reversible reaction of two reactants forming two products.

Name O-Phospho-4-hydroxy-L-threonine:2-oxoglutarate aminotransferase

Reaction equation M glu DASH L c + M ohpb c )−−−−* M akg c + M phthr c (1449)

Reactants

Table 1367: Properties of each reactant. Id Name SBO M glu DASH L c L-Glutamate M ohpb c 2-Oxo-3-hydroxy-4-phosphobutanoate

Products

Table 1368: Properties of each product. Id Name SBO M akg c 2-Oxoglutarate M phthr c O-Phospho-4-hydroxy-L-threonine

Kinetic Law

v725 = not speciﬁed (1450)

6.726 Reaction R OMCDC This is an irreversible reaction of two reactants forming two products.

Name 2-Oxo-4-methyl-3-carboxypentanoate decarboxylation

Reaction equation M 3c4mop c + M h c −→ M 4mop c + M co2 c (1451)

Reactants

Produced by SBML2LATEX 637 Table 1369: Properties of each reactant. Id Name SBO M 3c4mop c 3-Carboxy-4-methyl-2-oxopentanoate M h c H+

Products

Table 1370: Properties of each product. Id Name SBO M 4mop c 4-Methyl-2-oxopentanoate M co2 c CO2

Kinetic Law

v726 = not speciﬁed (1452)

6.727 Reaction R OMPDC This is an irreversible reaction of two reactants forming two products.

Name orotidine-5’-phosphate decarboxylase

Reaction equation M h c + M orot5p c −→ M co2 c + M ump c (1453)

Reactants

Table 1371: Properties of each reactant. Id Name SBO M h c H+ M orot5p c Orotidine 5’-phosphate

Products

Table 1372: Properties of each product. Id Name SBO M co2 c CO2

638 Produced by SBML2LATEX Id Name SBO M ump c UMP

Kinetic Law

v727 = not speciﬁed (1454)

6.728 Reaction R OPAH This is a reversible reaction of three reactants forming four products.

Name 5-Oxoproline amidohydrolase (ATP-hydrolysing)

Reaction equation M 5oxpro c + M atp c + 2M h2o c )−−−−* M adp c + M glu DASH L c + M h c + M pi c (1455)

Reactants

Table 1373: Properties of each reactant. Id Name SBO M 5oxpro c 5-Oxoproline M atp c ATP M h2o c H2O

Products

Table 1374: Properties of each product. Id Name SBO M adp c ADP M glu DASH L c L-Glutamate M h c H+ M pi c Phosphate

Kinetic Law

v728 = not speciﬁed (1456)

Produced by SBML2LATEX 639 6.729 Reaction R ORNTA This is an irreversible reaction of two reactants forming two products.

Name ornithine transaminase

Reaction equation M akg c + M orn c −→ M glu5sa c + M glu DASH L c (1457)

Reactants

Table 1375: Properties of each reactant. Id Name SBO M akg c 2-Oxoglutarate M orn c Ornithine

Products

Table 1376: Properties of each product. Id Name SBO M glu5sa c L-Glutamate 5-semialdehyde M glu DASH L c L-Glutamate

Kinetic Law

v729 = not speciﬁed (1458)

6.730 Reaction R ORNTAC This is a reversible reaction of two reactants forming two products.

Name ornithine transacetylase

Reaction equation M acorn c + M glu DASH L c )−−−−* M acglu c + M orn c (1459)

Reactants

640 Produced by SBML2LATEX Table 1377: Properties of each reactant. Id Name SBO M acorn c N2-Acetyl-L-ornithine M glu DASH L c L-Glutamate

Products

Table 1378: Properties of each product. Id Name SBO M acglu c N-Acetyl-L-glutamate M orn c Ornithine

Kinetic Law

v730 = not speciﬁed (1460)

6.731 Reaction R ORNt This is a reversible reaction of one reactant forming one product.

Name ornithine transport via diffusion (extracellular to periplasm)

Reaction equation M orn e )−−−−* M orn c (1461)

Reactant

Table 1379: Properties of each reactant. Id Name SBO M orn e Ornithine

Product

Table 1380: Properties of each product. Id Name SBO M orn c Ornithine

Produced by SBML2LATEX 641 Kinetic Law

v731 = not speciﬁed (1462)

6.732 Reaction R ORPT This is a reversible reaction of two reactants forming two products.

Name orotate phosphoribosyltransferase

Reaction equation M orot5p c + M ppi c )−−−−* M orot c + M prpp c (1463)

Reactants

Table 1381: Properties of each reactant. Id Name SBO M orot5p c Orotidine 5’-phosphate M ppi c Diphosphate

Products

Table 1382: Properties of each product. Id Name SBO M orot c Orotate M prpp c 5-Phospho-alpha-D-ribose 1-diphosphate

Kinetic Law

v732 = not speciﬁed (1464)

6.733 Reaction R OXACOAL This is a reversible reaction of three reactants forming three products.

Name oxalate-coa ligase

Reaction equation

M atp c + M coa c + M oxa c )−−−−* M amp c + M oxalcoa c + M ppi c (1465)

642 Produced by SBML2LATEX Reactants

Table 1383: Properties of each reactant. Id Name SBO M atp c ATP M coa c Coenzyme A M oxa c Oxalate

Products

Table 1384: Properties of each product. Id Name SBO M amp c AMP M oxalcoa c Oxalyl-CoA M ppi c Diphosphate

Kinetic Law

v733 = not speciﬁed (1466)

6.734 Reaction R OXCDC This is an irreversible reaction of two reactants forming two products.

Name Oxalyl-CoA decarboxylase

Reaction equation M h c + M oxalcoa c −→ M co2 c + M forcoa c (1467)

Reactants

Table 1385: Properties of each reactant. Id Name SBO M h c H+ M oxalcoa c Oxalyl-CoA

Products

Produced by SBML2LATEX 643 Table 1386: Properties of each product. Id Name SBO M co2 c CO2 M forcoa c Formyl-CoA

Kinetic Law

v734 = not speciﬁed (1468)

6.735 Reaction R OXGDC This is an irreversible reaction of two reactants forming two products.

Name 2-oxoglutarate decarboxylase

Reaction equation M akg c + M h c −→ M co2 c + M sucsal c (1469)

Reactants

Table 1387: Properties of each reactant. Id Name SBO M akg c 2-Oxoglutarate M h c H+

Products

Table 1388: Properties of each product. Id Name SBO M co2 c CO2 M sucsal c Succinic semialdehyde

Kinetic Law

v735 = not speciﬁed (1470)

6.736 Reaction R OXGDC2 This is an irreversible reaction of three reactants forming two products.

644 Produced by SBML2LATEX Name 2-oxoglutarate decarboxylase

Reaction equation M akg c + M h c + M thmpp c −→ M co2 c + M ssaltpp c (1471)

Reactants

Table 1389: Properties of each reactant. Id Name SBO M akg c 2-Oxoglutarate M h c H+ M thmpp c Thiamine diphosphate

Products

Table 1390: Properties of each product. Id Name SBO M co2 c CO2 M ssaltpp c Succinate semialdehyde-thiamin diphosphate anion

Kinetic Law

v736 = not speciﬁed (1472)

6.737 Reaction R P5CD This is an irreversible reaction of three reactants forming three products.

Name 1-pyrroline-5-carboxylate dehydrogenase

Reaction equation M 1pyr5c c + 2M h2o c + M nad c −→ M glu DASH L c + M h c + M nadh c (1473)

Reactants

Produced by SBML2LATEX 645 Table 1391: Properties of each reactant. Id Name SBO M 1pyr5c c 1-Pyrroline-5-carboxylate M h2o c H2O M nad c Nicotinamide adenine dinucleotide

Products

Table 1392: Properties of each product. Id Name SBO M glu DASH L c L-Glutamate M h c H+ M nadh c Nicotinamide adenine dinucleotide - reduced

Kinetic Law

v737 = not speciﬁed (1474)

6.738 Reaction R P5CR This is an irreversible reaction of three reactants forming two products.

Name pyrroline-5-carboxylate reductase

Reaction equation M 1pyr5c c + 2M h c + M nadph c −→ M nadp c + M pro DASH L c (1475)

Reactants

Table 1393: Properties of each reactant. Id Name SBO M 1pyr5c c 1-Pyrroline-5-carboxylate M h c H+ M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

Products

646 Produced by SBML2LATEX Table 1394: Properties of each product. Id Name SBO M nadp c Nicotinamide adenine dinucleotide phosphate M pro DASH L c L-Proline

Kinetic Law

v738 = not speciﬁed (1476)

6.739 Reaction R P5CRx This is an irreversible reaction of three reactants forming two products.

Name pyrroline-5-carboxylate reductase

Reaction equation M 1pyr5c c + 2M h c + M nadh c −→ M nad c + M pro DASH L c (1477)

Reactants

Table 1395: Properties of each reactant. Id Name SBO M 1pyr5c c 1-Pyrroline-5-carboxylate M h c H+ M nadh c Nicotinamide adenine dinucleotide - reduced

Products

Table 1396: Properties of each product. Id Name SBO M nad c Nicotinamide adenine dinucleotide M pro DASH L c L-Proline

Kinetic Law

v739 = not speciﬁed (1478)

Produced by SBML2LATEX 647 6.740 Reaction R PACt2r This is a reversible reaction of two reactants forming two products.

Name phenylacetate transport in via proton symporter

Reaction equation M h e + M pac e )−−−−* M h c + M pac c (1479)

Reactants

Table 1397: Properties of each reactant. Id Name SBO M h e H+ M pac e Phenylacetic acid

Products

Table 1398: Properties of each product. Id Name SBO M h c H+ M pac c Phenylacetic acid

Kinetic Law

v740 = not speciﬁed (1480)

6.741 Reaction R PANTS This is an irreversible reaction of three reactants forming four products.

Name pantothenate synthase

Reaction equation M ala DASH B c + M atp c + M pant DASH R c −→ M amp c + M h c + M pnto DASH R c + M ppi c (1481)

Reactants

648 Produced by SBML2LATEX Table 1399: Properties of each reactant. Id Name SBO M ala DASH B c beta-Alanine M atp c ATP M pant DASH R c (R)-Pantoate

Products

Table 1400: Properties of each product. Id Name SBO M amp c AMP M h c H+ M pnto DASH R c (R)-Pantothenate M ppi c Diphosphate

Kinetic Law

v741 = not speciﬁed (1482)

6.742 Reaction R PAPA160 This is an irreversible reaction of two reactants forming two products.

Name Phosphatidate phosphatase (n-C16:0)

Reaction equation M h2o c + M pa160 c −→ M 12dgr160 c + M pi c (1483)

Reactants

Table 1401: Properties of each reactant. Id Name SBO M h2o c H2O M pa160 c 1,2-dihexadecanoyl-sn-glycerol 3-phosphate

Products

Produced by SBML2LATEX 649 Table 1402: Properties of each product. Id Name SBO M 12dgr160 c 1,2-Diacyl-sn-glycerol (dihexadecanoyl, n-C16:0) M pi c Phosphate

Kinetic Law

v742 = not speciﬁed (1484)

6.743 Reaction R PAPPT1 This is an irreversible reaction of two reactants forming two products.

Name phospho-N-acetylmuramoyl-pentapeptide-transferase (alpha-glutamate)

Reaction equation M uAgla c + M udcpp c −→ M uaAgla c + M ump c (1485)

Reactants

Table 1403: Properties of each reactant. Id Name SBO M uAgla c UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine M udcpp c Undecaprenyl phosphate

Products

Table 1404: Properties of each product. Id Name SBO M uaAgla c Undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine M ump c UMP

Kinetic Law

v743 = not speciﬁed (1486)

6.744 Reaction R PAPPT2 This is an irreversible reaction of two reactants forming two products.

650 Produced by SBML2LATEX Name phospho-N-acetylmuramoyl-pentapeptide-transferase (gamma-glutamate)

Reaction equation M uGgla c + M udcpp c −→ M uaGgla c + M ump c (1487)

Reactants

Table 1405: Properties of each reactant. Id Name SBO M uGgla c UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine M udcpp c Undecaprenyl phosphate

Products

Table 1406: Properties of each product. Id Name SBO M uaGgla c Undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine M ump c UMP

Kinetic Law

v744 = not speciﬁed (1488)

6.745 Reaction R PAPPT3 This is an irreversible reaction of two reactants forming two products.

Name phospho-N-acetylmuramoyl-pentapeptide-transferase (meso-2,6-diaminopimelate)

Reaction equation M udcpp c + M ugmda c −→ M uagmda c + M ump c (1489)

Reactants

Table 1407: Properties of each reactant. Id Name SBO M udcpp c Undecaprenyl phosphate M ugmda c UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

Produced by SBML2LATEX 651 Products

Table 1408: Properties of each product. Id Name SBO M uagmda c Undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine M ump c UMP

Kinetic Law

v745 = not speciﬁed (1490)

6.746 Reaction R PAPR This is a reversible reaction of two reactants forming four products.

Name Phosphoadenosine phosphosulfate reductase

Reaction equation M paps c + M trdrd c )−−−−* 2M h c + M pap c + M so3 c + M trdox c (1491)

Reactants

Table 1409: Properties of each reactant. Id Name SBO M paps c 3’-Phosphoadenylyl sulfate M trdrd c Reduced thioredoxin

Products

Table 1410: Properties of each product. Id Name SBO M h c H+ M pap c Adenosine 3’,5’-bisphosphate M so3 c Sulﬁte M trdox c Oxidized thioredoxin

652 Produced by SBML2LATEX Kinetic Law

v746 = not speciﬁed (1492)

6.747 Reaction R PATS This is an irreversible reaction of four reactants forming two products.

Name penta-acyl trehalose synthesis

Reaction equation 5M h c + M ocdca c + 4M tmlgnc c + M tre c −→ 5M h2o c + M pat c (1493)

Reactants

Table 1411: Properties of each reactant. Id Name SBO M h c H+ M ocdca c octadecanoate (n-C18:0) M tmlgnc c tri-methyl lignoceric acid M tre c Trehalose

Products

Table 1412: Properties of each product. Id Name SBO M h2o c H2O M pat c penta-acyl trehalose

Kinetic Law

v747 = not speciﬁed (1494)

6.748 Reaction R PC

This is an irreversible reaction of three reactants forming four products.

Name pyruvate carboxylase

Produced by SBML2LATEX 653 Reaction equation M atp c + M hco3 c + M pyr c −→ M adp c + M h c + M oaa c + M pi c (1495)

Reactants

Table 1413: Properties of each reactant. Id Name SBO M atp c ATP M hco3 c Bicarbonate M pyr c Pyruvate

Products

Table 1414: Properties of each product. Id Name SBO M adp c ADP M h c H+ M oaa c Oxaloacetate M pi c Phosphate

Kinetic Law

v748 = not speciﬁed (1496)

6.749 Reaction R PC11M This is an irreversible reaction of two reactants forming three products.

Name precorrin-4 C11-methyltransferase

Reaction equation M amet c + M pre4 c −→ M ahcys c + M h c + M pre5 c (1497)

Reactants

Table 1415: Properties of each reactant. Id Name SBO M amet c S-Adenosyl-L-methionine

654 Produced by SBML2LATEX Id Name SBO M pre4 c Precorrin 4

Products

Table 1416: Properties of each product. Id Name SBO M ahcys c S-Adenosyl-L-homocysteine M h c H+ M pre5 c Precorrin 5

Kinetic Law

v749 = not speciﬁed (1498)

6.750 Reaction R PC17M This is an irreversible reaction of two reactants forming three products.

Name precorrin-3B C17-methyltransferase

Reaction equation M amet c + M pre3b c −→ M ahcys c + 3M h c + M pre4 c (1499)

Reactants

Table 1417: Properties of each reactant. Id Name SBO M amet c S-Adenosyl-L-methionine M pre3b c Precorrin 3B

Products

Table 1418: Properties of each product. Id Name SBO M ahcys c S-Adenosyl-L-homocysteine M h c H+

Produced by SBML2LATEX 655 Id Name SBO M pre4 c Precorrin 4

Kinetic Law

v750 = not speciﬁed (1500)

6.751 Reaction R PC20M This is an irreversible reaction of two reactants forming three products.

Name precorrin-2 C20-methyltransferase

Reaction equation M amet c + M dscl c −→ M ahcys c + M h c + M pre3a c (1501)

Reactants

Table 1419: Properties of each reactant. Id Name SBO M amet c S-Adenosyl-L-methionine M dscl c dihydrosirohydrochlorin

Products

Table 1420: Properties of each product. Id Name SBO M ahcys c S-Adenosyl-L-homocysteine M h c H+ M pre3a c Precorrin 3 A

Kinetic Law

v751 = not speciﬁed (1502)

6.752 Reaction R PC6AR This is an irreversible reaction of three reactants forming two products. Name precorrin-6A reductase

656 Produced by SBML2LATEX Reaction equation M h c + M nadph c + M pre6a c −→ M nadp c + M pre6b c (1503)

Reactants

Table 1421: Properties of each reactant. Id Name SBO M h c H+ M nadph c Nicotinamide adenine dinucleotide phosphate - reduced M pre6a c Precorrin 6A

Products

Table 1422: Properties of each product. Id Name SBO M nadp c Nicotinamide adenine dinucleotide phosphate M pre6b c Precorrin 6B

Kinetic Law

v752 = not speciﬁed (1504)

6.753 Reaction R PC6YM This is an irreversible reaction of two reactants forming four products.

Name precorrin-6Y C5,15-methyltransferase (decarboxylating)

Reaction equation 2M amet c + M pre6b c −→ 2M ahcys c + M co2 c + 2M h c + M pre8 c (1505)

Reactants

Table 1423: Properties of each reactant. Id Name SBO M amet c S-Adenosyl-L-methionine M pre6b c Precorrin 6B

Produced by SBML2LATEX 657 Products

Table 1424: Properties of each product. Id Name SBO M ahcys c S-Adenosyl-L-homocysteine M co2 c CO2 M h c H+ M pre8 c Precorrin 8

Kinetic Law

v753 = not speciﬁed (1506)

6.754 Reaction R PC8XM This is an irreversible reaction of two reactants forming one product.

Name precorrin-8X methylmutase

Reaction equation M h c + M pre8 c −→ M hgbyr c (1507)

Reactants

Table 1425: Properties of each reactant. Id Name SBO M h c H+ M pre8 c Precorrin 8

Product

Table 1426: Properties of each product. Id Name SBO M hgbyr c Hydrogenobyrinate

Kinetic Law

v754 = not speciﬁed (1508)

658 Produced by SBML2LATEX 6.755 Reaction R PDE1 This is an irreversible reaction of two reactants forming two products.

Name 3’,5’-cyclic-nucleotide phosphodiesterase

Reaction equation M camp c + M h2o c −→ M amp c + M h c (1509)

Reactants

Table 1427: Properties of each reactant. Id Name SBO M camp c cAMP M h2o c H2O

Products

Table 1428: Properties of each product. Id Name SBO M amp c AMP M h c H+

Kinetic Law

v755 = not speciﬁed (1510)

6.756 Reaction R PDE4 This is an irreversible reaction of two reactants forming two products.

Name 3’,5’-cyclic-nucleotide phosphodiesterase

Reaction equation M 35cgmp c + M h2o c −→ M gmp c + M h c (1511)

Reactants

Produced by SBML2LATEX 659 Table 1429: Properties of each reactant. Id Name SBO M 35cgmp c 3’,5’-Cyclic GMP M h2o c H2O

Products

Table 1430: Properties of each product. Id Name SBO M gmp c GMP M h c H+

Kinetic Law

v756 = not speciﬁed (1512)

6.757 Reaction R PDH This is an irreversible reaction of three reactants forming three products.

Name pyruvate dehydrogenase

Reaction equation M coa c + M nad c + M pyr c −→ M accoa c + M co2 c + M nadh c (1513)

Reactants

Table 1431: Properties of each reactant. Id Name SBO M coa c Coenzyme A M nad c Nicotinamide adenine dinucleotide M pyr c Pyruvate

Products

660 Produced by SBML2LATEX Table 1432: Properties of each product. Id Name SBO M accoa c Acetyl-CoA M co2 c CO2 M nadh c Nicotinamide adenine dinucleotide - reduced

Kinetic Law

v757 = not speciﬁed (1514)

6.758 Reaction R PDHa This is an irreversible reaction of three reactants forming two products.

Name pyruvate dehydrogenase (lipoamide)

Reaction equation M h c + M lpam c + M pyr c −→ M adhlam c + M co2 c (1515)

Reactants

Table 1433: Properties of each reactant. Id Name SBO M h c H+ M lpam c Lipoamide M pyr c Pyruvate

Products

Table 1434: Properties of each product. Id Name SBO M adhlam c S-Acetyldihydrolipoamide M co2 c CO2

Kinetic Law

v758 = not speciﬁed (1516)

Produced by SBML2LATEX 661 6.759 Reaction R PDHbr This is a reversible reaction of two reactants forming two products.

Name pyruvate dehydrogenase (dihydrolipoamide) reversible

Reaction equation M adhlam c + M coa c )−−−−* M accoa c + M dhlam c (1517)

Reactants

Table 1435: Properties of each reactant. Id Name SBO M adhlam c S-Acetyldihydrolipoamide M coa c Coenzyme A

Products

Table 1436: Properties of each product. Id Name SBO M accoa c Acetyl-CoA M dhlam c Dihydrolipoamide

Kinetic Law

v759 = not speciﬁed (1518)

6.760 Reaction R PDHc This is an irreversible reaction of two reactants forming three products.

Name pyruvate dehydrogenase (dihydrolipoamide dehydrogenase)

Reaction equation M dhlam c + M nad c −→ M h c + M lpam c + M nadh c (1519)

Reactants

662 Produced by SBML2LATEX Table 1437: Properties of each reactant. Id Name SBO M dhlam c Dihydrolipoamide M nad c Nicotinamide adenine dinucleotide

Products

Table 1438: Properties of each product. Id Name SBO M h c H+ M lpam c Lipoamide M nadh c Nicotinamide adenine dinucleotide - reduced

Kinetic Law

v760 = not speciﬁed (1520)

6.761 Reaction R PDHcr This is a reversible reaction of two reactants forming three products.

Name Pyruvate dehydrogenase (dihydrolipoamide dehydrogenase) reversible

Reaction equation M dhlam c + M nad c )−−−−* M h c + M lpam c + M nadh c (1521)

Reactants

Table 1439: Properties of each reactant. Id Name SBO M dhlam c Dihydrolipoamide M nad c Nicotinamide adenine dinucleotide

Products

Produced by SBML2LATEX 663 Table 1440: Properties of each product. Id Name SBO M h c H+ M lpam c Lipoamide M nadh c Nicotinamide adenine dinucleotide - reduced

Kinetic Law

v761 = not speciﬁed (1522)

6.762 Reaction R PDIMAS This is an irreversible reaction of three reactants forming two products.

Name PDIM A synthesis (Mycobacterium Tuberculosis)

Reaction equation 2M h c + M phthiocerol c + 2M tamocta c −→ 2M h2o c + M pdima c (1523)

Reactants

Table 1441: Properties of each reactant. Id Name SBO M h c H+ M phthiocerol c phthiocerol A M tamocta c tetra-methyl octacosanoate

Products

Table 1442: Properties of each product. Id Name SBO M h2o c H2O M pdima c phthiocerol dimycocerosate A (Mtb)

Kinetic Law

v762 = not speciﬁed (1524)

664 Produced by SBML2LATEX 6.763 Reaction R PDIMAT This is an irreversible reaction of one reactant forming one product.

Name pdima translocase

Reaction equation M pdima c −→ M pdima e (1525)

Reactant

Table 1443: Properties of each reactant. Id Name SBO M pdima c phthiocerol dimycocerosate A (Mtb)

Product

Table 1444: Properties of each product. Id Name SBO M pdima e phthiocerol dimycocerosate A (Mtb)

Kinetic Law

v763 = not speciﬁed (1526)

6.764 Reaction R PDX5PO This is a reversible reaction of two reactants forming two products.

Name pyridoxine 5’-phosphate oxidase

Reaction equation M o2 c + M pdx5p c )−−−−* M h2o2 c + M pydx5p c (1527)

Reactants

Produced by SBML2LATEX 665 Table 1445: Properties of each reactant. Id Name SBO M o2 c O2 M pdx5p c Pyridoxine 5’-phosphate

Products

Table 1446: Properties of each product. Id Name SBO M h2o2 c Hydrogen peroxide M pydx5p c Pyridoxal 5’-phosphate

Kinetic Law

v764 = not speciﬁed (1528)

6.765 Reaction R PEAMNO This is an irreversible reaction of three reactants forming three products.

Name Phenethylamine oxidase

Reaction equation M h2o c + M o2 c + M peamn c −→ M h2o2 c + M nh4 c + M pacald c (1529)

Reactants

Table 1447: Properties of each reactant. Id Name SBO M h2o c H2O M o2 c O2 M peamn c Phenethylamine

Products

666 Produced by SBML2LATEX Table 1448: Properties of each product. Id Name SBO M h2o2 c Hydrogen peroxide M nh4 c Ammonium M pacald c Phenylacetaldehyde

Kinetic Law

v765 = not speciﬁed (1530)

6.766 Reaction R PEPCK re This is a reversible reaction of two reactants forming three products.

Name phosphoenolpyruvate carboxykinase (GTP)

Reaction equation M gtp c + M oaa c )−−−−* M co2 c + M gdp c + M pep c (1531)

Reactants

Table 1449: Properties of each reactant. Id Name SBO M gtp c GTP M oaa c Oxaloacetate

Products

Table 1450: Properties of each product. Id Name SBO M co2 c CO2 M gdp c GDP M pep c Phosphoenolpyruvate

Kinetic Law

v766 = not speciﬁed (1532)

Produced by SBML2LATEX 667 6.767 Reaction R PERD This is a reversible reaction of two reactants forming three products.

Name Erythronate 4-phosphate (4per) dehydrogenase

Reaction equation M 4per c + M nad c )−−−−* M h c + M nadh c + M ohpb c (1533)

Reactants

Table 1451: Properties of each reactant. Id Name SBO M 4per c 4-Phospho-D-erythronate M nad c Nicotinamide adenine dinucleotide

Products

Table 1452: Properties of each product. Id Name SBO M h c H+ M nadh c Nicotinamide adenine dinucleotide - reduced M ohpb c 2-Oxo-3-hydroxy-4-phosphobutanoate

Kinetic Law

v767 = not speciﬁed (1534)

6.768 Reaction R PFK This is an irreversible reaction of two reactants forming three products.

Name phosphofructokinase

Reaction equation M atp c + M f6p c −→ M adp c + M fdp c + M h c (1535)

Reactants

668 Produced by SBML2LATEX Table 1453: Properties of each reactant. Id Name SBO M atp c ATP M f6p c D-Fructose 6-phosphate

Products

Table 1454: Properties of each product. Id Name SBO M adp c ADP M fdp c D-Fructose 1,6-bisphosphate M h c H+

Kinetic Law

v768 = not speciﬁed (1536)

6.769 Reaction R PFL This is an irreversible reaction of two reactants forming two products.

Name pyruvate formate lyase

Reaction equation M coa c + M pyr c −→ M accoa c + M for c (1537)

Reactants

Table 1455: Properties of each reactant. Id Name SBO M coa c Coenzyme A M pyr c Pyruvate

Products

Produced by SBML2LATEX 669 Table 1456: Properties of each product. Id Name SBO M accoa c Acetyl-CoA M for c Formate

Kinetic Law

v769 = not speciﬁed (1538)

6.770 Reaction R PGAMT This is a reversible reaction of one reactant forming one product.

Name phosphoglucosamine mutase

Reaction equation M gam1p c )−−−−* M gam6p c (1539)

Reactant

Table 1457: Properties of each reactant. Id Name SBO M gam1p c D-Glucosamine 1-phosphate

Product

Table 1458: Properties of each product. Id Name SBO M gam6p c D-Glucosamine 6-phosphate

Kinetic Law

v770 = not speciﬁed (1540)

6.771 Reaction R PGCD This is an irreversible reaction of two reactants forming three products.

Name phosphoglycerate dehydrogenase

670 Produced by SBML2LATEX Reaction equation M 3pg c + M nad c −→ M 3php c + M h c + M nadh c (1541)

Reactants

Table 1459: Properties of each reactant. Id Name SBO M 3pg c 3-Phospho-D-glycerate M nad c Nicotinamide adenine dinucleotide

Products

Table 1460: Properties of each product. Id Name SBO M 3php c 3-Phosphohydroxypyruvate M h c H+ M nadh c Nicotinamide adenine dinucleotide - reduced

Kinetic Law

v771 = not speciﬁed (1542)

6.772 Reaction R PGI This is a reversible reaction of one reactant forming one product.

Name glucose-6-phosphate isomerase

Reaction equation M g6p c )−−−−* M f6p c (1543)

Reactant

Table 1461: Properties of each reactant. Id Name SBO M g6p c D-Glucose 6-phosphate

Produced by SBML2LATEX 671 Product

Table 1462: Properties of each product. Id Name SBO M f6p c D-Fructose 6-phosphate

Kinetic Law

v772 = not speciﬁed (1544)

6.773 Reaction R PGK This is a reversible reaction of two reactants forming two products.

Name phosphoglycerate kinase

Reaction equation M 3pg c + M atp c )−−−−* M 13dpg c + M adp c (1545)

Reactants

Table 1463: Properties of each reactant. Id Name SBO M 3pg c 3-Phospho-D-glycerate M atp c ATP

Products

Table 1464: Properties of each product. Id Name SBO M 13dpg c 3-Phospho-D-glyceroyl phosphate M adp c ADP

Kinetic Law

v773 = not speciﬁed (1546)

672 Produced by SBML2LATEX 6.774 Reaction R PGL This is an irreversible reaction of two reactants forming two products.

Name 6-phosphogluconolactonase

Reaction equation M 6pgl c + M h2o c −→ M 6pgc c + M h c (1547)

Reactants

Table 1465: Properties of each reactant. Id Name SBO M 6pgl c 6-phospho-D-glucono-1,5-lactone M h2o c H2O

Products

Table 1466: Properties of each product. Id Name SBO M 6pgc c 6-Phospho-D-gluconate M h c H+

Kinetic Law

v774 = not speciﬁed (1548)

6.775 Reaction R PGLS This is an irreversible reaction of two reactants forming three products.

Name methoxy fucose rhamnose rhamnose phenol phthiocerol dimycocerosate synthesis

Reaction equation 4M amet c + M frrppdima c −→ 4M ahcys c + 4M h c + M mfrrppdima c (1549)

Reactants

Produced by SBML2LATEX 673 Table 1467: Properties of each reactant. Id Name SBO M amet c S-Adenosyl-L-methionine M frrppdima c fucose rhamnose rhamnose phenol phthiocerol dimycocerosate (Mtb)

Products

Table 1468: Properties of each product. Id Name SBO M ahcys c S-Adenosyl-L-homocysteine M h c H+ M mfrrppdima c phenolic glycolipid (Mtb)

Kinetic Law

v775 = not speciﬁed (1550)

6.776 Reaction R PGLYCP This is an irreversible reaction of two reactants forming two products.

Name Phosphoglycolate phosphatase

Reaction equation M 2pglyc c + M h2o c −→ M glyclt c + M pi c (1551)

Reactants

Table 1469: Properties of each reactant. Id Name SBO M 2pglyc c 2-Phosphoglycolate M h2o c H2O

Products

674 Produced by SBML2LATEX Table 1470: Properties of each product. Id Name SBO M glyclt c Glycolate M pi c Phosphate

Kinetic Law

v776 = not speciﬁed (1552)

6.777 Reaction R PGM This is a reversible reaction of one reactant forming one product.

Name phosphoglycerate mutase

Reaction equation M 2pg c )−−−−* M 3pg c (1553)

Reactant

Table 1471: Properties of each reactant. Id Name SBO M 2pg c D-Glycerate 2-phosphate

Product

Table 1472: Properties of each product. Id Name SBO M 3pg c 3-Phospho-D-glycerate

Kinetic Law

v777 = not speciﬁed (1554)

6.778 Reaction R PGMT This is a reversible reaction of one reactant forming one product.

Name phosphoglucomutase

Produced by SBML2LATEX 675 Reaction equation M g1p c )−−−−* M g6p c (1555)

Reactant

Table 1473: Properties of each reactant. Id Name SBO M g1p c D-Glucose 1-phosphate

Product

Table 1474: Properties of each product. Id Name SBO M g6p c D-Glucose 6-phosphate

Kinetic Law

v778 = not speciﬁed (1556)

6.779 Reaction R PGPP160 This is an irreversible reaction of two reactants forming two products.

Name phosphatidylglycerol phosphate phosphatase (n-C16:0)

Reaction equation M h2o c + M pgp160 c −→ M pg160 c + M pi c (1557)

Reactants

Table 1475: Properties of each reactant. Id Name SBO M h2o c H2O M pgp160 c Phosphatidylglycerophosphate (dihexadecanoyl, n-C16:0)

Products

676 Produced by SBML2LATEX Table 1476: Properties of each product. Id Name SBO M pg160 c Phosphatidylglycerol (dihexadecanoyl, n-C16:0) M pi c Phosphate

Kinetic Law

v779 = not speciﬁed (1558)

6.780 Reaction R PGPP160190 This is an irreversible reaction of two reactants forming two products.

Name phosphatidylglycerol phosphate phosphatase (C16:0, C19:0)

Reaction equation M h2o c + M pgp160190 c −→ M pg160190 c + M pi c (1559)

Reactants

Table 1477: Properties of each reactant. Id Name SBO M h2o c H2O M pgp160190 c Phosphatidylglycerophosphate (hexadecanoyl, tuberculostearoyl, C16:0, C19:0)

Products

Table 1478: Properties of each product. Id Name SBO M pg160190 c Phosphatidylglycerol (hexadecanoyl, methylstearoyl) M pi c Phosphate

Kinetic Law

v780 = not speciﬁed (1560)

6.781 Reaction R PGPP190 This is an irreversible reaction of two reactants forming two products.

Produced by SBML2LATEX 677 Name phosphatidylglycerol phosphate phosphatase (C19:0)

Reaction equation M h2o c + M pgp190 c −→ M pg190 c + M pi c (1561)

Reactants

Table 1479: Properties of each reactant. Id Name SBO M h2o c H2O M pgp190 c Phosphatidylglycerophosphate (dituberculostearoyl, C19:0)

Products

Table 1480: Properties of each product. Id Name SBO M pg190 c Phosphatidylglycerol (dimethylstearoyl, C19:0) M pi c Phosphate

Kinetic Law

v781 = not speciﬁed (1562)

6.782 Reaction R PGPPT3 This is an irreversible reaction of two reactants forming two products.

Name phospho-N-glycolylmuramoyl-pentapeptide-transferase (meso-2,6-diaminopimelate)

Reaction equation M udcpp c + M uggmda c −→ M ugggmda c + M ump c (1563)

Reactants

Table 1481: Properties of each reactant. Id Name SBO M udcpp c Undecaprenyl phosphate M uggmda c UDP-N-glycolylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

678 Produced by SBML2LATEX Products

Table 1482: Properties of each product. Id Name SBO M ugggmda c Undecaprenyl-diphospho-N-glycolylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine M ump c UMP

Kinetic Law

v782 = not speciﬁed (1564)

6.783 Reaction R PGSA160 This is an irreversible reaction of two reactants forming three products.

Name Phosphatidylglycerol synthase (n-C16:0)

Reaction equation M cdpdhdecg c + M glyc3p c −→ M cmp c + M h c + M pgp160 c (1565)

Reactants

Table 1483: Properties of each reactant. Id Name SBO M cdpdhdecg c CDP-1,2-dihexadecanoylglycerol M glyc3p c Glycerol 3-phosphate

Products

Table 1484: Properties of each product. Id Name SBO M cmp c CMP M h c H+ M pgp160 c Phosphatidylglycerophosphate (dihexadecanoyl, n-C16:0)

Kinetic Law

v783 = not speciﬁed (1566)

Produced by SBML2LATEX 679 6.784 Reaction R PGSA160190 This is an irreversible reaction of two reactants forming three products.

Name Phosphatidylglycerol synthase (C16:0,C19:0)

Reaction equation M cdpc16c19g c + M glyc3p c −→ M cmp c + M h c + M pgp160190 c (1567)

Reactants

Table 1485: Properties of each reactant. Id Name SBO M cdpc16c19g c cdp diacylglycerol (C16:0, C19:0) M glyc3p c Glycerol 3-phosphate

Products

Table 1486: Properties of each product. Id Name SBO M cmp c CMP M h c H+ M pgp160190 c Phosphatidylglycerophosphate (hexadecanoyl, tuberculostearoyl, C16:0, C19:0)

Kinetic Law

v784 = not speciﬁed (1568)

6.785 Reaction R PGSA190 This is an irreversible reaction of two reactants forming three products.

Name Phosphatidylglycerol synthase (C19:0)

Reaction equation M cdpc19c19g c + M glyc3p c −→ M cmp c + M h c + M pgp190 c (1569)

Reactants

680 Produced by SBML2LATEX Table 1487: Properties of each reactant. Id Name SBO M cdpc19c19g c cdp diacylglycerol (C19:0, C19:0) M glyc3p c Glycerol 3-phosphate

Products

Table 1488: Properties of each product. Id Name SBO M cmp c CMP M h c H+ M pgp190 c Phosphatidylglycerophosphate (dituberculostearoyl, C19:0)

Kinetic Law

v785 = not speciﬁed (1570)

6.786 Reaction R PHDCATA This is a reversible reaction of two reactants forming two products.

Name transacylase

Reaction equation M ACP c + M phdcacoa c )−−−−* M coa c + M phdcaACP c (1571)

Reactants

Table 1489: Properties of each reactant. Id Name SBO M ACP c acyl carrier protein M phdcacoa c phenol palmitic coenzyme A

Products

Produced by SBML2LATEX 681 Table 1490: Properties of each product. Id Name SBO M coa c Coenzyme A M phdcaACP c phenol palmitic acid ACP

Kinetic Law

v786 = not speciﬁed (1572)

6.787 Reaction R PHDCAt This is a reversible reaction of one reactant forming one product.

Name phenol palmitic acid via diffusion (extracellular)

Reaction equation M phdca e )−−−−* M phdca c (1573)

Reactant

Table 1491: Properties of each reactant. Id Name SBO M phdca e phenol palmitic acid

Product

Table 1492: Properties of each product. Id Name SBO M phdca c phenol palmitic acid

Kinetic Law

v787 = not speciﬁed (1574)

6.788 Reaction R PHETA1 This is a reversible reaction of two reactants forming two products.

Name phenylalanine transaminase

682 Produced by SBML2LATEX Reaction equation M akg c + M phe DASH L c )−−−−* M glu DASH L c + M phpyr c (1575)

Reactants

Table 1493: Properties of each reactant. Id Name SBO M akg c 2-Oxoglutarate M phe DASH L c L-Phenylalanine

Products

Table 1494: Properties of each product. Id Name SBO M glu DASH L c L-Glutamate M phpyr c Phenylpyruvate

Kinetic Law

v788 = not speciﬁed (1576)

6.789 Reaction R PHEt2r This is a reversible reaction of two reactants forming two products.

Name L-phenylalanine reversible transport via proton symport

Reaction equation M h e + M phe DASH L e )−−−−* M h c + M phe DASH L c (1577)

Reactants

Table 1495: Properties of each reactant. Id Name SBO M h e H+ M phe DASH L e L-Phenylalanine

Produced by SBML2LATEX 683 Products

Table 1496: Properties of each product. Id Name SBO M h c H+ M phe DASH L c L-Phenylalanine

Kinetic Law

v789 = not speciﬁed (1578)

6.790 Reaction R PHTHCLR1 This is a reversible reaction of two reactants forming three products.

Name phthiocol reductase (NAD)

Reaction equation M nad c + M phthclh2 c )−−−−* M h c + M nadh c + M phthcl c (1579)

Reactants

Table 1497: Properties of each reactant. Id Name SBO M nad c Nicotinamide adenine dinucleotide M phthclh2 c phthiocol (reduced)

Products

Table 1498: Properties of each product. Id Name SBO M h c H+ M nadh c Nicotinamide adenine dinucleotide - reduced M phthcl c phthiocol (oxidized)

Kinetic Law

v790 = not speciﬁed (1580)

684 Produced by SBML2LATEX 6.791 Reaction R PHTHCLR2 This is a reversible reaction of two reactants forming three products.

Name phthiocol reductase (NAD)

Reaction equation M nadp c + M phthclh2 c )−−−−* M h c + M nadph c + M phthcl c (1581)

Reactants

Table 1499: Properties of each reactant. Id Name SBO M nadp c Nicotinamide adenine dinucleotide phosphate M phthclh2 c phthiocol (reduced)

Products

Table 1500: Properties of each product. Id Name SBO M h c H+ M nadph c Nicotinamide adenine dinucleotide phosphate - reduced M phthcl c phthiocol (oxidized)

Kinetic Law

v791 = not speciﬁed (1582)

6.792 Reaction R PHTHCLS This is an irreversible reaction of four reactants forming three products.

Name phthiocol synthesis

Reaction equation M h c + M mndn c + M nadph c + M o2 c −→ M h2o c + M nadp c + M phthcl c (1583)

Reactants

Produced by SBML2LATEX 685 Table 1501: Properties of each reactant. Id Name SBO M h c H+ M mndn c menadione M nadph c Nicotinamide adenine dinucleotide phosphate - reduced M o2 c O2

Products

Table 1502: Properties of each product. Id Name SBO M h2o c H2O M nadp c Nicotinamide adenine dinucleotide phosphate M phthcl c phthiocol (oxidized)

Kinetic Law

v792 = not speciﬁed (1584)

6.793 Reaction R PHTHDLS This is an irreversible reaction of two reactants forming two products.

Name phthiodolone synthesis

Reaction equation M h c + M prephth c −→ M co2 c + M phthdl c (1585)

Reactants

Table 1503: Properties of each reactant. Id Name SBO M h c H+ M prephth c phthiocerol precursor

Products

686 Produced by SBML2LATEX Table 1504: Properties of each product. Id Name SBO M co2 c CO2 M phthdl c phthiodolone

Kinetic Law

v793 = not speciﬁed (1586)

6.794 Reaction R PHTHDLS2 This is an irreversible reaction of two reactants forming two products.

Name phenolphthiodolone synthesis

Reaction equation M h c + M prepphth c −→ M co2 c + M pphthdl c (1587)

Reactants

Table 1505: Properties of each reactant. Id Name SBO M h c H+ M prepphth c phenolic phthiocerol precursor

Products

Table 1506: Properties of each product. Id Name SBO M co2 c CO2 M pphthdl c phenolic phthiodiolone

Kinetic Law

v794 = not speciﬁed (1588)

6.795 Reaction R PHTHS This is an irreversible reaction of three reactants forming three products.

Produced by SBML2LATEX 687 Name phthiocerol synthesis

Reaction equation M amet c + M nadph c + M phthdl c −→ M ahcys c + M nadp c + M phthiocerol c (1589)

Reactants

Table 1507: Properties of each reactant. Id Name SBO M amet c S-Adenosyl-L-methionine M nadph c Nicotinamide adenine dinucleotide phosphate - reduced M phthdl c phthiodolone

Products

Table 1508: Properties of each product. Id Name SBO M ahcys c S-Adenosyl-L-homocysteine M nadp c Nicotinamide adenine dinucleotide phosphate M phthiocerol c phthiocerol A

Kinetic Law

v795 = not speciﬁed (1590)

6.796 Reaction R PHTHS2 This is an irreversible reaction of three reactants forming three products.

Name phenolphthiocerol synthesis

Reaction equation M amet c + M nadph c + M pphthdl c −→ M ahcys c + M nadp c + M pphthiocerol c (1591)

Reactants

688 Produced by SBML2LATEX Table 1509: Properties of each reactant. Id Name SBO M amet c S-Adenosyl-L-methionine M nadph c Nicotinamide adenine dinucleotide phosphate - reduced M pphthdl c phenolic phthiodiolone

Products

Table 1510: Properties of each product. Id Name SBO M ahcys c S-Adenosyl-L-homocysteine M nadp c Nicotinamide adenine dinucleotide phosphate M pphthiocerol c phenolphtiocerol

Kinetic Law

v796 = not speciﬁed (1592)

6.797 Reaction R PHTO This is an irreversible reaction of two reactants forming three products.

Name phthiocol oxygenase

Reaction equation 2M o2 c + M phthclh2 c −→ 2M h c + 2M o2s c + M phthcl c (1593)

Reactants

Table 1511: Properties of each reactant. Id Name SBO M o2 c O2 M phthclh2 c phthiocol (reduced)

Products

Produced by SBML2LATEX 689 Table 1512: Properties of each product. Id Name SBO M h c H+ M o2s c Superoxide anion M phthcl c phthiocol (oxidized)

Kinetic Law

v797 = not speciﬁed (1594)

6.798 Reaction R PHYCBOXL This is an irreversible reaction of two reactants forming two products.

Name L-Phenylalanine carboxy-lyase

Reaction equation M h c + M phe DASH L c −→ M co2 c + M peamn c (1595)

Reactants

Table 1513: Properties of each reactant. Id Name SBO M h c H+ M phe DASH L c L-Phenylalanine

Products

Table 1514: Properties of each product. Id Name SBO M co2 c CO2 M peamn c Phenethylamine

Kinetic Law

v798 = not speciﬁed (1596)

690 Produced by SBML2LATEX 6.799 Reaction R PIabc This is an irreversible reaction of three reactants forming three products.

Name phosphate transport via ABC system

Reaction equation M atp c + M h2o c + M pi e −→ M adp c + M h c + 2M pi c (1597)

Reactants

Table 1515: Properties of each reactant. Id Name SBO M atp c ATP M h2o c H2O M pi e Phosphate

Products

Table 1516: Properties of each product. Id Name SBO M adp c ADP M h c H+ M pi c Phosphate

Kinetic Law

v799 = not speciﬁed (1598)

6.800 Reaction R PIt This is a reversible reaction of one reactant forming one product.

Name Inorganic phosphate exchange, diffusion

Reaction equation M pi c )−−−−* M pi e (1599)

Reactant

Produced by SBML2LATEX 691 Table 1517: Properties of each reactant. Id Name SBO M pi c Phosphate

Product

Table 1518: Properties of each product. Id Name SBO M pi e Phosphate

Kinetic Law

v800 = not speciﬁed (1600)

6.801 Reaction R PLCD This is an irreversible reaction of two reactants forming three products.

Name phospholipase C

Reaction equation M h2o c + M ptd1ino160 c −→ M 12dgr160 c + M h c + M mi1p DASH D c (1601)

Reactants

Table 1519: Properties of each reactant. Id Name SBO M h2o c H2O M ptd1ino160 c phosphatidyl 1D myo inositol

Products

Table 1520: Properties of each product. Id Name SBO M 12dgr160 c 1,2-Diacyl-sn-glycerol (dihexadecanoyl, n-C16:0) M h c H+ M mi1p DASH D c 1D-myo-Inositol 1-phosphate

692 Produced by SBML2LATEX Id Name SBO

Kinetic Law

v801 = not speciﬁed (1602)

6.802 Reaction R PLIPA1E160 This is an irreversible reaction of two reactants forming three products.

Name Phospholipase A1 (phosphatidylethanolamine, n-C16:0)

Reaction equation M h2o c + M pe160 c −→ M 2agpe160 c + M h c + M hdca c (1603)

Reactants

Table 1521: Properties of each reactant. Id Name SBO M h2o c H2O M pe160 c phosphatidylethanolamine (dihexadecanoyl, n-C16:0)

Products

Table 1522: Properties of each product. Id Name SBO M 2agpe160 c 2-Acyl-sn-glycero-3-phosphoethanolamine (n-C16:0) M h c H+ M hdca c Hexadecanoate (n-C16:0)

Kinetic Law

v802 = not speciﬁed (1604)

6.803 Reaction R PLIPA1E180 This is an irreversible reaction of two reactants forming three products.

Name Phospholipase A1 (phosphatidylethanolamine, n-C18:0)

Produced by SBML2LATEX 693 Reaction equation M h2o c + M pe180 c −→ M 2agpe180 c + M h c + M ocdca c (1605)

Reactants

Table 1523: Properties of each reactant. Id Name SBO M h2o c H2O M pe180 c phosphatidylethanolamine (dioctadecanoyl, n-C18:0)

Products

Table 1524: Properties of each product. Id Name SBO M 2agpe180 c 2-Acyl-sn-glycero-3-phosphoethanolamine (n-C18:0) M h c H+ M ocdca c octadecanoate (n-C18:0)

Kinetic Law

v803 = not speciﬁed (1606)

6.804 Reaction R PMANM This is a reversible reaction of one reactant forming one product.

Name phosphomannomutase

Reaction equation M man1p c )−−−−* M man6p c (1607)

Reactant

Table 1525: Properties of each reactant. Id Name SBO M man1p c D-Mannose 1-phosphate

694 Produced by SBML2LATEX Product

Table 1526: Properties of each product. Id Name SBO M man6p c D-Mannose 6-phosphate

Kinetic Law

v804 = not speciﬁed (1608)

6.805 Reaction R PMDPHT This is an irreversible reaction of two reactants forming two products.

Name pyrimidine phosphatase

Reaction equation M 5aprbu c + M h2o c −→ M 4r5au c + M pi c (1609)

Reactants

Table 1527: Properties of each reactant. Id Name SBO M 5aprbu c 5-Amino-6-(5’-phosphoribitylamino)uracil M h2o c H2O

Products

Table 1528: Properties of each product. Id Name SBO M 4r5au c 4-(1-D-Ribitylamino)-5-aminouracil M pi c Phosphate

Kinetic Law

v805 = not speciﬁed (1610)

Produced by SBML2LATEX 695 6.806 Reaction R PMPK This is an irreversible reaction of two reactants forming two products.

Name phosphomethylpyrimidine kinase

Reaction equation M 4ampm c + M atp c −→ M 2mahmp c + M adp c (1611)

Reactants

Table 1529: Properties of each reactant. Id Name SBO M 4ampm c 4-Amino-2-methyl-5-phosphomethylpyrimidine M atp c ATP

Products

Table 1530: Properties of each product. Id Name SBO M 2mahmp c 2-Methyl-4-amino-5-hydroxymethylpyrimidine diphosphate M adp c ADP

Kinetic Law

v806 = not speciﬁed (1612)

6.807 Reaction R PNCDC This is an irreversible reaction of two reactants forming two products.

Name pantothenoylcysteine decarboxylase

Reaction equation M h c + M ptcys c −→ M co2 c + M ptth c (1613)

Reactants

696 Produced by SBML2LATEX Table 1531: Properties of each reactant. Id Name SBO M h c H+ M ptcys c N-Pantothenoylcysteine

Products

Table 1532: Properties of each product. Id Name SBO M co2 c CO2 M ptth c Pantetheine

Kinetic Law

v807 = not speciﬁed (1614)

6.808 Reaction R PNTK This is an irreversible reaction of two reactants forming three products.

Name pantothenate kinase

Reaction equation M atp c + M pnto DASH R c −→ M 4ppan c + M adp c + M h c (1615)

Reactants

Table 1533: Properties of each reactant. Id Name SBO M atp c ATP M pnto DASH R c (R)-Pantothenate

Products

Table 1534: Properties of each product. Id Name SBO M 4ppan c D-4’-Phosphopantothenate

Produced by SBML2LATEX 697 Id Name SBO M adp c ADP M h c H+

Kinetic Law

v808 = not speciﬁed (1616)

6.809 Reaction R PPA This is an irreversible reaction of two reactants forming two products.

Name inorganic diphosphatase

Reaction equation M h2o c + M ppi c −→ M h c + 2M pi c (1617)

Reactants

Table 1535: Properties of each reactant. Id Name SBO M h2o c H2O M ppi c Diphosphate

Products

Table 1536: Properties of each product. Id Name SBO M h c H+ M pi c Phosphate

Kinetic Law

v809 = not speciﬁed (1618)

6.810 Reaction R PPAtr This is a reversible reaction of one reactant forming one product. Name Propionate transport, diffusion

698 Produced by SBML2LATEX Reaction equation M ppa e )−−−−* M ppa c (1619)

Reactant

Table 1537: Properties of each reactant. Id Name SBO M ppa e Propionate (n-C3:0)

Product

Table 1538: Properties of each product. Id Name SBO M ppa c Propionate (n-C3:0)

Kinetic Law

v810 = not speciﬁed (1620)

6.811 Reaction R PPBNGS This is an irreversible reaction of one reactant forming three products.

Name porphobilinogen synthase

Reaction equation 2M 5aop c −→ 2M h2o c + M h c + M ppbng c (1621)

Reactant

Table 1539: Properties of each reactant. Id Name SBO M 5aop c 5-Amino-4-oxopentanoate

Products

Produced by SBML2LATEX 699 Table 1540: Properties of each product. Id Name SBO M h2o c H2O M h c H+ M ppbng c Porphobilinogen

Kinetic Law

v811 = not speciﬁed (1622)

6.812 Reaction R PPCDC This is an irreversible reaction of two reactants forming two products.

Name phosphopantothenoylcysteine decarboxylase

Reaction equation M 4ppcys c + M h c −→ M co2 c + M pan4p c (1623)

Reactants

Table 1541: Properties of each reactant. Id Name SBO M 4ppcys c N-((R)-4-Phosphopantothenoyl)-L-cysteine M h c H+

Products

Table 1542: Properties of each product. Id Name SBO M co2 c CO2 M pan4p c Pantetheine 4’-phosphate

Kinetic Law

v812 = not speciﬁed (1624)

700 Produced by SBML2LATEX 6.813 Reaction R PPCKr This is a reversible reaction of two reactants forming three products.

Name phosphoenolpyruvate carboxykinase

Reaction equation M atp c + M oaa c )−−−−* M adp c + M co2 c + M pep c (1625)

Reactants

Table 1543: Properties of each reactant. Id Name SBO M atp c ATP M oaa c Oxaloacetate

Products

Table 1544: Properties of each product. Id Name SBO M adp c ADP M co2 c CO2 M pep c Phosphoenolpyruvate

Kinetic Law

v813 = not speciﬁed (1626)

6.814 Reaction R PPCOAC This is an irreversible reaction of three reactants forming four products.

Name Propionyl-CoA carboxylase

Reaction equation M atp c + M hco3 c + M ppcoa c −→ M adp c + M h c + M mmcoa DASH S c + M pi c (1627)

Reactants

Produced by SBML2LATEX 701 Table 1545: Properties of each reactant. Id Name SBO M atp c ATP M hco3 c Bicarbonate M ppcoa c Propanoyl-CoA

Products

Table 1546: Properties of each product. Id Name SBO M adp c ADP M h c H+ M mmcoa DASH S c (S)-Methylmalonyl-CoA M pi c Phosphate

Kinetic Law

v814 = not speciﬁed (1628)

6.815 Reaction R PPCSCT This is an irreversible reaction of two reactants forming two products.

Name Propanoyl-CoA: succinate CoA-transferase

Reaction equation M ppcoa c + M succ c −→ M ppa c + M succoa c (1629)

Reactants

Table 1547: Properties of each reactant. Id Name SBO M ppcoa c Propanoyl-CoA M succ c Succinate

Products

702 Produced by SBML2LATEX Table 1548: Properties of each product. Id Name SBO M ppa c Propionate (n-C3:0) M succoa c Succinyl-CoA

Kinetic Law

v815 = not speciﬁed (1630)

6.816 Reaction R PPDIMAS This is an irreversible reaction of three reactants forming two products.

Name PPDIM synthesis (Mycobacterium Tuberculosis)

Reaction equation 2M h c + M pphthiocerol c + 2M tamocta c −→ 2M h2o c + M ppdima c (1631)

Reactants

Table 1549: Properties of each reactant. Id Name SBO M h c H+ M pphthiocerol c phenolphtiocerol M tamocta c tetra-methyl octacosanoate

Products

Table 1550: Properties of each product. Id Name SBO M h2o c H2O M ppdima c phenol phthiocerol dimycocerosate (Mtb)

Kinetic Law

v816 = not speciﬁed (1632)

Produced by SBML2LATEX 703 6.817 Reaction R PPDIMAT This is an irreversible reaction of one reactant forming one product.

Name ppdima translocase

Reaction equation M ppdima c −→ M ppdima e (1633)

Reactant

Table 1551: Properties of each reactant. Id Name SBO M ppdima c phenol phthiocerol dimycocerosate (Mtb)

Product

Table 1552: Properties of each product. Id Name SBO M ppdima e phenol phthiocerol dimycocerosate (Mtb)

Kinetic Law

v817 = not speciﬁed (1634)

6.818 Reaction R PPDK This is an irreversible reaction of three reactants forming four products.

Name Pyruvate,phosphate dikinase.

Reaction equation M atp c + M pi c + M pyr c −→ M amp c + M h c + M pep c + M ppi c (1635)

Reactants

704 Produced by SBML2LATEX Table 1553: Properties of each reactant. Id Name SBO M atp c ATP M pi c Phosphate M pyr c Pyruvate

Products

Table 1554: Properties of each product. Id Name SBO M amp c AMP M h c H+ M pep c Phosphoenolpyruvate M ppi c Diphosphate

Kinetic Law

v818 = not speciﬁed (1636)

6.819 Reaction R PPGKr This is a reversible reaction of two reactants forming two products.

Name Polyphosphate glucokinase reversible

Reaction equation M glc DASH D c + M pi c )−−−−* M g6p c + M h2o c (1637)

Reactants

Table 1555: Properties of each reactant. Id Name SBO M glc DASH D c D-Glucose M pi c Phosphate

Products

Produced by SBML2LATEX 705 Table 1556: Properties of each product. Id Name SBO M g6p c D-Glucose 6-phosphate M h2o c H2O

Kinetic Law

v819 = not speciﬁed (1638)

6.820 Reaction R PPK2 This is an irreversible reaction of two reactants forming two products.

Name polyphosphate kinase

Reaction equation M atp c + M ppi c −→ M adp c + M pppi c (1639)

Reactants

Table 1557: Properties of each reactant. Id Name SBO M atp c ATP M ppi c Diphosphate

Products

Table 1558: Properties of each product. Id Name SBO M adp c ADP M pppi c Inorganic triphosphate

Kinetic Law

v820 = not speciﬁed (1640)

6.821 Reaction R PPNCL This is an irreversible reaction of three reactants forming four products.

706 Produced by SBML2LATEX Name phosphopantothenate-cysteine ligase

Reaction equation M 4ppan c + M ctp c + M cys DASH L c −→ M 4ppcys c + M cdp c + M h c + M pi c (1641)

Reactants

Table 1559: Properties of each reactant. Id Name SBO M 4ppan c D-4’-Phosphopantothenate M ctp c CTP M cys DASH L c L-Cysteine

Products

Table 1560: Properties of each product. Id Name SBO M 4ppcys c N-((R)-4-Phosphopantothenoyl)-L-cysteine M cdp c CDP M h c H+ M pi c Phosphate

Kinetic Law

v821 = not speciﬁed (1642)

6.822 Reaction R PPNCL2 This is an irreversible reaction of three reactants forming four products.

Name phosphopantothenate-cysteine ligase

Reaction equation M 4ppan c + M ctp c + M cys DASH L c −→ M 4ppcys c + M cmp c + M h c + M ppi c (1643)

Reactants

Produced by SBML2LATEX 707 Table 1561: Properties of each reactant. Id Name SBO M 4ppan c D-4’-Phosphopantothenate M ctp c CTP M cys DASH L c L-Cysteine

Products

Table 1562: Properties of each product. Id Name SBO M 4ppcys c N-((R)-4-Phosphopantothenoyl)-L-cysteine M cmp c CMP M h c H+ M ppi c Diphosphate

Kinetic Law

v822 = not speciﬁed (1644)

6.823 Reaction R PPNCL3 This is an irreversible reaction of three reactants forming four products.

Name phosphopantothenate-cysteine ligase

Reaction equation M 4ppan c + M atp c + M cys DASH L c −→ M 4ppcys c + M amp c + M h c + M ppi c (1645)

Reactants

Table 1563: Properties of each reactant. Id Name SBO M 4ppan c D-4’-Phosphopantothenate M atp c ATP M cys DASH L c L-Cysteine

708 Produced by SBML2LATEX Products

Table 1564: Properties of each product. Id Name SBO M 4ppcys c N-((R)-4-Phosphopantothenoyl)-L-cysteine M amp c AMP M h c H+ M ppi c Diphosphate

Kinetic Law

v823 = not speciﬁed (1646)

6.824 Reaction R PPND This is an irreversible reaction of two reactants forming three products.

Name prephenate dehydrogenase

Reaction equation M nad c + M pphn c −→ M 34hpp c + M co2 c + M nadh c (1647)

Reactants

Table 1565: Properties of each reactant. Id Name SBO M nad c Nicotinamide adenine dinucleotide M pphn c Prephenate

Products

Table 1566: Properties of each product. Id Name SBO M 34hpp c 3-(4-Hydroxyphenyl)pyruvate M co2 c CO2 M nadh c Nicotinamide adenine dinucleotide - reduced

Produced by SBML2LATEX 709 Kinetic Law

v824 = not speciﬁed (1648)

6.825 Reaction R PPNDH This is an irreversible reaction of two reactants forming three products.

Name prephenate dehydratase

Reaction equation M h c + M pphn c −→ M co2 c + M h2o c + M phpyr c (1649)

Reactants

Table 1567: Properties of each reactant. Id Name SBO M h c H+ M pphn c Prephenate

Products

Table 1568: Properties of each product. Id Name SBO M co2 c CO2 M h2o c H2O M phpyr c Phenylpyruvate

Kinetic Law

v825 = not speciﬁed (1650)

6.826 Reaction R PPPGO This is an irreversible reaction of two reactants forming two products.

Name protoporphyrinogen oxidase (aerobic)

Reaction equation 1·5M o2 c + M pppg9 c −→ 3M h2o c + M ppp9 c (1651)

710 Produced by SBML2LATEX Reactants

Table 1569: Properties of each reactant. Id Name SBO M o2 c O2 M pppg9 c Protoporphyrinogen IX

Products

Table 1570: Properties of each product. Id Name SBO M h2o c H2O M ppp9 c Protoporphyrin

Kinetic Law

v826 = not speciﬁed (1652)

6.827 Reaction R PPTGS This is an irreversible reaction of one reactant forming three products.

Name Peptidoglycan subunit synthesis

Reaction equation M uaagmda c −→ M h c + M peptido EC c + M udcpdp c (1653)

Reactant

Table 1571: Properties of each reactant. Id Name SBO M uaagmda c Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-ala-D-glu-meso-2,6-diaminopimeloyl-D-ala-D-ala

Products

Produced by SBML2LATEX 711 Table 1572: Properties of each product. Id Name SBO M h c H+ M peptido EC c Peptidoglycan subunit of Escherichia coli M udcpdp c Undecaprenyl diphosphate

Kinetic Law

v827 = not speciﬁed (1654)

6.828 Reaction R PPTGS TB1 This is an irreversible reaction of one reactant forming three products.

Name Peptidoglycan subunit synthesis

Reaction equation M uaaAgla c −→ M h c + M peptido TB1 c + M udcpdp c (1655)

Reactant

Table 1573: Properties of each reactant. Id Name SBO M uaaAgla c Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine

Products

Table 1574: Properties of each product. Id Name SBO M h c H+ M peptido TB1 c peptidoglycan subunit (for Mycobacterium tuberculosis) M udcpdp c Undecaprenyl diphosphate

Kinetic Law

v828 = not speciﬁed (1656)

712 Produced by SBML2LATEX 6.829 Reaction R PPTGS TB2 This is an irreversible reaction of one reactant forming three products.

Name Peptidoglycan subunit synthesis

Reaction equation M uaaGgla c −→ M h c + M peptido TB2 c + M udcpdp c (1657)

Reactant

Table 1575: Properties of each reactant. Id Name SBO M uaaGgla c Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine

Products

Table 1576: Properties of each product. Id Name SBO M h c H+ M peptido TB2 c peptidoglycan subunit (for Mycobacterium tuberculosis) M udcpdp c Undecaprenyl diphosphate

Kinetic Law

v829 = not speciﬁed (1658)

6.830 Reaction R PRAGSr This is a reversible reaction of three reactants forming four products.

Name phosphoribosylglycinamide synthase

Reaction equation M atp c + M gly c + M pram c )−−−−* M adp c + M gar c + M h c + M pi c (1659)

Reactants

Produced by SBML2LATEX 713 Table 1577: Properties of each reactant. Id Name SBO M atp c ATP M gly c Glycine M pram c 5-Phospho-beta-D-ribosylamine

Products

Table 1578: Properties of each product. Id Name SBO M adp c ADP M gar c N1-(5-Phospho-D-ribosyl)glycinamide M h c H+ M pi c Phosphate

Kinetic Law

v830 = not speciﬁed (1660)

6.831 Reaction R PRAIS This is an irreversible reaction of two reactants forming four products.

Name phosphoribosylaminoimidazole synthase

Reaction equation M atp c + M fpram c −→ M adp c + M air c + 2M h c + M pi c (1661)

Reactants

Table 1579: Properties of each reactant. Id Name SBO M atp c ATP M fpram c 2-(Formamido)-N1-(5-phospho-D-ribosyl)acetamidine

Products

714 Produced by SBML2LATEX Table 1580: Properties of each product. Id Name SBO M adp c ADP M air c 5-amino-1-(5-phospho-D-ribosyl)imidazole M h c H+ M pi c Phosphate

Kinetic Law

v831 = not speciﬁed (1662)

6.832 Reaction R PRAIi This is an irreversible reaction of one reactant forming one product.

Name phosphoribosylanthranilate isomerase (irreversible)

Reaction equation M pran c −→ M 2cpr5p c (1663)

Reactant

Table 1581: Properties of each reactant. Id Name SBO M pran c N-(5-Phospho-D-ribosyl)anthranilate

Product

Table 1582: Properties of each product. Id Name SBO M 2cpr5p c 1-(2-Carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate

Kinetic Law

v832 = not speciﬁed (1664)

6.833 Reaction R PRAMPC This is an irreversible reaction of two reactants forming one product.

Produced by SBML2LATEX 715 Name phosphoribosyl-AMP cyclohydrolase

Reaction equation M h2o c + M prbamp c −→ M prfp c (1665)

Reactants

Table 1583: Properties of each reactant. Id Name SBO M h2o c H2O M prbamp c 1-(5-Phosphoribosyl)-AMP

Product

Table 1584: Properties of each product. Id Name SBO M prfp c 1-(5-Phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

Kinetic Law

v833 = not speciﬁed (1666)

6.834 Reaction R PRASCS This is a reversible reaction of three reactants forming four products.

Name phosphoribosylaminoimidazolesuccinocarboxamide synthase

Reaction equation M 5aizc c + M asp DASH L c + M atp c )−−−−* M 25aics c + M adp c + M h c + M pi c (1667)

Reactants

Table 1585: Properties of each reactant. Id Name SBO M 5aizc c 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

716 Produced by SBML2LATEX Id Name SBO M asp DASH L c L-Aspartate M atp c ATP

Products

Table 1586: Properties of each product. Id Name SBO M 25aics c (S)-2-[5-Amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido]succinate M adp c ADP M h c H+ M pi c Phosphate

Kinetic Law

v834 = not speciﬁed (1668)

6.835 Reaction R PRATPP This is an irreversible reaction of two reactants forming three products.

Name phosphoribosyl-ATP pyrophosphatase

Reaction equation M h2o c + M prbatp c −→ M h c + M ppi c + M prbamp c (1669)

Reactants

Table 1587: Properties of each reactant. Id Name SBO M h2o c H2O M prbatp c 1-(5-Phosphoribosyl)-ATP

Products

Produced by SBML2LATEX 717 Table 1588: Properties of each product. Id Name SBO M h c H+ M ppi c Diphosphate M prbamp c 1-(5-Phosphoribosyl)-AMP

Kinetic Law

v835 = not speciﬁed (1670)

6.836 Reaction R PRDX This is an irreversible reaction of two reactants forming two products.

Name Peroxidase (multiple substrates)

Reaction equation M h2o2 c + M meoh c −→ M fald c + 2M h2o c (1671)

Reactants

Table 1589: Properties of each reactant. Id Name SBO M h2o2 c Hydrogen peroxide M meoh c Methanol

Products

Table 1590: Properties of each product. Id Name SBO M fald c Formaldehyde M h2o c H2O

Kinetic Law

v836 = not speciﬁed (1672)

718 Produced by SBML2LATEX 6.837 Reaction R PREPHACPH This is an irreversible reaction of two reactants forming three products.

Name fatty-acyl-ACP hydrolase

Reaction equation M h2o c + M prephthACP c −→ M ACP c + M h c + M prephth c (1673)

Reactants

Table 1591: Properties of each reactant. Id Name SBO M h2o c H2O M prephthACP c phthiocerol precursor bound ACP

Products

Table 1592: Properties of each product. Id Name SBO M ACP c acyl carrier protein M h c H+ M prephth c phthiocerol precursor

Kinetic Law

v837 = not speciﬁed (1674)

6.838 Reaction R PREPPACPH This is an irreversible reaction of two reactants forming three products.

Name fatty-acyl-ACP hydrolase

Reaction equation M h2o c + M prepphthACP c −→ M ACP c + M h c + M prepphth c (1675)

Reactants

Produced by SBML2LATEX 719 Table 1593: Properties of each reactant. Id Name SBO M h2o c H2O M prepphthACP c phenolic phthiocerol precursor bound ACP

Products

Table 1594: Properties of each product. Id Name SBO M ACP c acyl carrier protein M h c H+ M prepphth c phenolic phthiocerol precursor

Kinetic Law

v838 = not speciﬁed (1676)

6.839 Reaction R PREPTHS This is an irreversible reaction of ﬁve reactants forming ﬁve products.

Name phthiocerol precursor synthesis

Reaction equation M arachACP c + 14M h c + 2M malcoa c + 2M mmcoa DASH S c + 10M nadph c −→ 2M co2 c + 4M coa c + 5M h2o c + 10M nadp c + M prephthACP c (1677)

Reactants

Table 1595: Properties of each reactant. Id Name SBO M arachACP c eicosanoyl-ACP (n-C20:0) M h c H+ M malcoa c Malonyl-CoA M mmcoa DASH S c (S)-Methylmalonyl-CoA M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

720 Produced by SBML2LATEX Products

Table 1596: Properties of each product. Id Name SBO M co2 c CO2 M coa c Coenzyme A M h2o c H2O M nadp c Nicotinamide adenine dinucleotide phosphate M prephthACP c phthiocerol precursor bound ACP

Kinetic Law

v839 = not speciﬁed (1678)

6.840 Reaction R PREPTHS2 This is an irreversible reaction of ﬁve reactants forming ﬁve products.

Name phenolic phthiocerol precursor synthesis

Reaction equation 14M h c + 2M malcoa c + 2M mmcoa DASH S c + 10M nadph c + M phdcaACP c −→ 2M co2 c + 4M coa c + 5M h2o c + 10M nadp c + M prepphthACP c (1679)

Reactants

Table 1597: Properties of each reactant. Id Name SBO M h c H+ M malcoa c Malonyl-CoA M mmcoa DASH S c (S)-Methylmalonyl-CoA M nadph c Nicotinamide adenine dinucleotide phosphate - reduced M phdcaACP c phenol palmitic acid ACP

Products

Produced by SBML2LATEX 721 Table 1598: Properties of each product. Id Name SBO M co2 c CO2 M coa c Coenzyme A M h2o c H2O M nadp c Nicotinamide adenine dinucleotide phosphate M prepphthACP c phenolic phthiocerol precursor bound ACP

Kinetic Law

v840 = not speciﬁed (1680)

6.841 Reaction R PREPTTA This is a reversible reaction of two reactants forming two products.

Name phthiocerol precursor ACP transacylase

Reaction equation M ACP c + M prephthcoa c )−−−−* M coa c + M prephthACP c (1681)

Reactants

Table 1599: Properties of each reactant. Id Name SBO M ACP c acyl carrier protein M prephthcoa c phthiocerol precursor bound coenzyme A

Products

Table 1600: Properties of each product. Id Name SBO M coa c Coenzyme A M prephthACP c phthiocerol precursor bound ACP

Kinetic Law

v841 = not speciﬁed (1682)

722 Produced by SBML2LATEX 6.842 Reaction R PRFGS This is an irreversible reaction of four reactants forming ﬁve products.

Name phosphoribosylformylglycinamidine synthase

Reaction equation M atp c + M fgam c + M gln DASH L c + M h2o c −→ M adp c + M fpram c + M glu DASH L c + M h c + M pi c (1683)

Reactants

Table 1601: Properties of each reactant. Id Name SBO M atp c ATP M fgam c N2-Formyl-N1-(5-phospho-D-ribosyl)glycinamide M gln DASH L c L-Glutamine M h2o c H2O

Products

Table 1602: Properties of each product. Id Name SBO M adp c ADP M fpram c 2-(Formamido)-N1-(5-phospho-D-ribosyl)acetamidine M glu DASH L c L-Glutamate M h c H+ M pi c Phosphate

Kinetic Law

v842 = not speciﬁed (1684)

6.843 Reaction R PRMICIi This is an irreversible reaction of one reactant forming one product.

Name 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (irreversible)

Produced by SBML2LATEX 723 Reaction equation M prfp c −→ M prlp c (1685)

Reactant

Table 1603: Properties of each reactant. Id Name SBO M prfp c 1-(5-Phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

Product

Table 1604: Properties of each product. Id Name SBO M prlp c 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]-1-(5-phosphoribosyl)imidazole-4-carboxamide

Kinetic Law

v843 = not speciﬁed (1686)

6.844 Reaction R PROD2 This is an irreversible reaction of two reactants forming three products.

Name Proline dehydrogenase

Reaction equation M fad c + M pro DASH L c −→ M 1pyr5c c + M fadh2 c + M h c (1687)

Reactants

Table 1605: Properties of each reactant. Id Name SBO M fad c Flavin adenine dinucleotide oxidized M pro DASH L c L-Proline

Products

724 Produced by SBML2LATEX Table 1606: Properties of each product. Id Name SBO M 1pyr5c c 1-Pyrroline-5-carboxylate M fadh2 c Flavin adenine dinucleotide reduced M h c H+

Kinetic Law

v844 = not speciﬁed (1688)

6.845 Reaction R PROabc This is an irreversible reaction of three reactants forming four products.

Name L-proline transport via ABC system

Reaction equation M atp c + M h2o c + M pro DASH L e −→ M adp c + M h c + M pi c + M pro DASH L c (1689)

Reactants

Table 1607: Properties of each reactant. Id Name SBO M atp c ATP M h2o c H2O M pro DASH L e L-Proline

Products

Table 1608: Properties of each product. Id Name SBO M adp c ADP M h c H+ M pi c Phosphate M pro DASH L c L-Proline

Produced by SBML2LATEX 725 Kinetic Law

v845 = not speciﬁed (1690)

6.846 Reaction R PROt2r This is a reversible reaction of two reactants forming two products.

Name L-proline reversible transport via proton symport

Reaction equation M h e + M pro DASH L e )−−−−* M h c + M pro DASH L c (1691)

Reactants

Table 1609: Properties of each reactant. Id Name SBO M h e H+ M pro DASH L e L-Proline

Products

Table 1610: Properties of each product. Id Name SBO M h c H+ M pro DASH L c L-Proline

Kinetic Law

v846 = not speciﬁed (1692)

6.847 Reaction R PRPPS This is a reversible reaction of two reactants forming three products.

Name phosphoribosylpyrophosphate synthetase

Reaction equation

M atp c + M r5p c )−−−−* M amp c + M h c + M prpp c (1693)

726 Produced by SBML2LATEX Reactants

Table 1611: Properties of each reactant. Id Name SBO M atp c ATP M r5p c alpha-D-Ribose 5-phosphate

Products

Table 1612: Properties of each product. Id Name SBO M amp c AMP M h c H+ M prpp c 5-Phospho-alpha-D-ribose 1-diphosphate

Kinetic Law

v847 = not speciﬁed (1694)

6.848 Reaction R PSCVT This is a reversible reaction of two reactants forming two products.

Name 3-phosphoshikimate 1-carboxyvinyltransferase

Reaction equation M pep c + M skm5p c )−−−−* M 3psme c + M pi c (1695)

Reactants

Table 1613: Properties of each reactant. Id Name SBO M pep c Phosphoenolpyruvate M skm5p c Shikimate 5-phosphate

Products

Produced by SBML2LATEX 727 Table 1614: Properties of each product. Id Name SBO M 3psme c 5-O-(1-Carboxyvinyl)-3-phosphoshikimate M pi c Phosphate

Kinetic Law

v848 = not speciﬁed (1696)

6.849 Reaction R PSD160 This is an irreversible reaction of two reactants forming two products.

Name Phosphatidylserine decarboxylase (n-C16:0)

Reaction equation M h c + M ps160 c −→ M co2 c + M pe160 c (1697)

Reactants

Table 1615: Properties of each reactant. Id Name SBO M h c H+ M ps160 c phosphatidylserine (dihexadecanoyl, n-C16:0)

Products

Table 1616: Properties of each product. Id Name SBO M co2 c CO2 M pe160 c phosphatidylethanolamine (dihexadecanoyl, n-C16:0)

Kinetic Law

v849 = not speciﬁed (1698)

6.850 Reaction R PSD180 This is an irreversible reaction of two reactants forming two products.

728 Produced by SBML2LATEX Name Phosphatidylserine decarboxylase (n-C18:0)

Reaction equation M h c + M ps180 c −→ M co2 c + M pe180 c (1699)

Reactants

Table 1617: Properties of each reactant. Id Name SBO M h c H+ M ps180 c phosphatidylserine (dioctadecanoyl, n-C18:0)

Products

Table 1618: Properties of each product. Id Name SBO M co2 c CO2 M pe180 c phosphatidylethanolamine (dioctadecanoyl, n-C18:0)

Kinetic Law

v850 = not speciﬁed (1700)

6.851 Reaction R PSERT This is an irreversible reaction of two reactants forming two products.

Name phosphoserine transaminase

Reaction equation M 3php c + M glu DASH L c −→ M akg c + M pser DASH L c (1701)

Reactants

Table 1619: Properties of each reactant. Id Name SBO M 3php c 3-Phosphohydroxypyruvate M glu DASH L c L-Glutamate

Produced by SBML2LATEX 729 Products

Table 1620: Properties of each product. Id Name SBO M akg c 2-Oxoglutarate M pser DASH L c O-Phospho-L-serine

Kinetic Law

v851 = not speciﬁed (1702)

6.852 Reaction R PSP L This is an irreversible reaction of two reactants forming two products.

Name phosphoserine phosphatase (L-serine)

Reaction equation M h2o c + M pser DASH L c −→ M pi c + M ser DASH L c (1703)

Reactants

Table 1621: Properties of each reactant. Id Name SBO M h2o c H2O M pser DASH L c O-Phospho-L-serine

Products

Table 1622: Properties of each product. Id Name SBO M pi c Phosphate M ser DASH L c L-Serine

Kinetic Law

v852 = not speciﬁed (1704)

730 Produced by SBML2LATEX 6.853 Reaction R PSSA160 This is an irreversible reaction of two reactants forming three products.

Name Phosphatidylserine syntase (n-C16:0)

Reaction equation M cdpdhdecg c + M ser DASH L c −→ M cmp c + M h c + M ps160 c (1705)

Reactants

Table 1623: Properties of each reactant. Id Name SBO M cdpdhdecg c CDP-1,2-dihexadecanoylglycerol M ser DASH L c L-Serine

Products

Table 1624: Properties of each product. Id Name SBO M cmp c CMP M h c H+ M ps160 c phosphatidylserine (dihexadecanoyl, n-C16:0)

Kinetic Law

v853 = not speciﬁed (1706)

6.854 Reaction R PSSA180 This is an irreversible reaction of two reactants forming three products.

Name Phosphatidylserine syntase (n-C18:0)

Reaction equation M cdpdodecg c + M ser DASH L c −→ M cmp c + M h c + M ps180 c (1707)

Reactants

Produced by SBML2LATEX 731 Table 1625: Properties of each reactant. Id Name SBO M cdpdodecg c CDP-1,2-dioctadecanoylglycerol M ser DASH L c L-Serine

Products

Table 1626: Properties of each product. Id Name SBO M cmp c CMP M h c H+ M ps180 c phosphatidylserine (dioctadecanoyl, n-C18:0)

Kinetic Law

v854 = not speciﬁed (1708)

6.855 Reaction R PTAr This is a reversible reaction of two reactants forming two products.

Name phosphotransacetylase

Reaction equation M accoa c + M pi c )−−−−* M actp c + M coa c (1709)

Reactants

Table 1627: Properties of each reactant. Id Name SBO M accoa c Acetyl-CoA M pi c Phosphate

Products

732 Produced by SBML2LATEX Table 1628: Properties of each product. Id Name SBO M actp c Acetyl phosphate M coa c Coenzyme A

Kinetic Law

v855 = not speciﬁed (1710)

6.856 Reaction R PTPATi This is an irreversible reaction of three reactants forming two products.

Name pantetheine-phosphate adenylyltransferase

Reaction equation M atp c + M h c + M pan4p c −→ M dpcoa c + M ppi c (1711)

Reactants

Table 1629: Properties of each reactant. Id Name SBO M atp c ATP M h c H+ M pan4p c Pantetheine 4’-phosphate

Products

Table 1630: Properties of each product. Id Name SBO M dpcoa c Dephospho-CoA M ppi c Diphosphate

Kinetic Law

v856 = not speciﬁed (1712)

Produced by SBML2LATEX 733 6.857 Reaction R PUNP1 This is a reversible reaction of two reactants forming two products.

Name purine-nucleoside phosphorylase (Adenosine)

Reaction equation M adn c + M pi c )−−−−* M ade c + M r1p c (1713)

Reactants

Table 1631: Properties of each reactant. Id Name SBO M adn c Adenosine M pi c Phosphate

Products

Table 1632: Properties of each product. Id Name SBO M ade c Adenine M r1p c alpha-D-Ribose 1-phosphate

Kinetic Law

v857 = not speciﬁed (1714)

6.858 Reaction R PUNP2 This is a reversible reaction of two reactants forming two products.

Name purine-nucleoside phosphorylase (Deoxyadenosine)

Reaction equation M dad DASH 2 c + M pi c )−−−−* M 2dr1p c + M ade c (1715)

Reactants

734 Produced by SBML2LATEX Table 1633: Properties of each reactant. Id Name SBO M dad DASH 2 c Deoxyadenosine M pi c Phosphate

Products

Table 1634: Properties of each product. Id Name SBO M 2dr1p c 2-Deoxy-D-ribose 1-phosphate M ade c Adenine

Kinetic Law

v858 = not speciﬁed (1716)

6.859 Reaction R PUNP3 This is a reversible reaction of two reactants forming two products.

Name purine-nucleoside phosphorylase (Guanosine)

Reaction equation M gsn c + M pi c )−−−−* M gua c + M r1p c (1717)

Reactants

Table 1635: Properties of each reactant. Id Name SBO M gsn c Guanosine M pi c Phosphate

Products

Table 1636: Properties of each product. Id Name SBO M gua c Guanine

Produced by SBML2LATEX 735 Id Name SBO M r1p c alpha-D-Ribose 1-phosphate

Kinetic Law

v859 = not speciﬁed (1718)

6.860 Reaction R PUNP4 This is a reversible reaction of two reactants forming two products.

Name purine-nucleoside phosphorylase (Deoxyguanosine)

Reaction equation M dgsn c + M pi c )−−−−* M 2dr1p c + M gua c (1719)

Reactants

Table 1637: Properties of each reactant. Id Name SBO M dgsn c Deoxyguanosine M pi c Phosphate

Products

Table 1638: Properties of each product. Id Name SBO M 2dr1p c 2-Deoxy-D-ribose 1-phosphate M gua c Guanine

Kinetic Law

v860 = not speciﬁed (1720)

6.861 Reaction R PUNP5 This is a reversible reaction of two reactants forming two products.

Name purine-nucleoside phosphorylase (Inosine)

736 Produced by SBML2LATEX Reaction equation M ins c + M pi c )−−−−* M hxan c + M r1p c (1721)

Reactants

Table 1639: Properties of each reactant. Id Name SBO M ins c Inosine M pi c Phosphate

Products

Table 1640: Properties of each product. Id Name SBO M hxan c Hypoxanthine M r1p c alpha-D-Ribose 1-phosphate

Kinetic Law

v861 = not speciﬁed (1722)

6.862 Reaction R PUNP6 This is a reversible reaction of two reactants forming two products.

Name purine-nucleoside phosphorylase (Deoxyinosine)

Reaction equation M din c + M pi c )−−−−* M 2dr1p c + M hxan c (1723)

Reactants

Table 1641: Properties of each reactant. Id Name SBO M din c Deoxyinosine M pi c Phosphate

Produced by SBML2LATEX 737 Products

Table 1642: Properties of each product. Id Name SBO M 2dr1p c 2-Deoxy-D-ribose 1-phosphate M hxan c Hypoxanthine

Kinetic Law

v862 = not speciﬁed (1724)

6.863 Reaction R PUNP7 This is a reversible reaction of two reactants forming two products.

Name purine-nucleoside phosphorylase (Xanthosine)

Reaction equation M pi c + M xtsn c )−−−−* M r1p c + M xan c (1725)

Reactants

Table 1643: Properties of each reactant. Id Name SBO M pi c Phosphate M xtsn c Xanthosine

Products

Table 1644: Properties of each product. Id Name SBO M r1p c alpha-D-Ribose 1-phosphate M xan c Xanthine

Kinetic Law

v863 = not speciﬁed (1726)

738 Produced by SBML2LATEX 6.864 Reaction R PYAM5PO This is an irreversible reaction of three reactants forming three products.

Name pyridoxamine 5’-phosphate oxidase

Reaction equation M h2o c + M o2 c + M pyam5p c −→ M h2o2 c + M nh4 c + M pydx5p c (1727)

Reactants

Table 1645: Properties of each reactant. Id Name SBO M h2o c H2O M o2 c O2 M pyam5p c Pyridoxamine 5’-phosphate

Products

Table 1646: Properties of each product. Id Name SBO M h2o2 c Hydrogen peroxide M nh4 c Ammonium M pydx5p c Pyridoxal 5’-phosphate

Kinetic Law

v864 = not speciﬁed (1728)

6.865 Reaction R PYDXNO This is a reversible reaction of two reactants forming two products.

Name pyridoxine oxidase

Reaction equation M o2 c + M pydxn c )−−−−* M h2o2 c + M pydx c (1729)

Reactants

Produced by SBML2LATEX 739 Table 1647: Properties of each reactant. Id Name SBO M o2 c O2 M pydxn c Pyridoxine

Products

Table 1648: Properties of each product. Id Name SBO M h2o2 c Hydrogen peroxide M pydx c Pyridoxal

Kinetic Law

v865 = not speciﬁed (1730)

6.866 Reaction R PYDXO This is a reversible reaction of four reactants forming two products.

Name pyridoxal oxidase

Reaction equation 2M h2o c + M nh4 c + 0·5M o2 c + M pydx c )−−−−* 2M h2o2 c + M pydam c (1731)

Reactants

Table 1649: Properties of each reactant. Id Name SBO M h2o c H2O M nh4 c Ammonium M o2 c O2 M pydx c Pyridoxal

Products

740 Produced by SBML2LATEX Table 1650: Properties of each product. Id Name SBO M h2o2 c Hydrogen peroxide M pydam c Pyridoxamine

Kinetic Law

v866 = not speciﬁed (1732)

6.867 Reaction R PYK This is an irreversible reaction of three reactants forming two products.

Name pyruvate kinase

Reaction equation M adp c + M h c + M pep c −→ M atp c + M pyr c (1733)

Reactants

Table 1651: Properties of each reactant. Id Name SBO M adp c ADP M h c H+ M pep c Phosphoenolpyruvate

Products

Table 1652: Properties of each product. Id Name SBO M atp c ATP M pyr c Pyruvate

Kinetic Law

v867 = not speciﬁed (1734)

Produced by SBML2LATEX 741 6.868 Reaction R PYRDC This is an irreversible reaction of two reactants forming two products.

Name pyruvate decarboxylase

Reaction equation M h c + M pyr c −→ M acald c + M co2 c (1735)

Reactants

Table 1653: Properties of each reactant. Id Name SBO M h c H+ M pyr c Pyruvate

Products

Table 1654: Properties of each product. Id Name SBO M acald c Acetaldehyde M co2 c CO2

Kinetic Law

v868 = not speciﬁed (1736)

6.869 Reaction R PYRt2r This is a reversible reaction of two reactants forming two products.

Name pyruvate reversible transport via proton symport

Reaction equation M h e + M pyr e )−−−−* M h c + M pyr c (1737)

Reactants

742 Produced by SBML2LATEX Table 1655: Properties of each reactant. Id Name SBO M h e H+ M pyr e Pyruvate

Products

Table 1656: Properties of each product. Id Name SBO M h c H+ M pyr c Pyruvate

Kinetic Law

v869 = not speciﬁed (1738)

6.870 Reaction R QRr This is a reversible reaction of three reactants forming two products.

Name Quinone reductase

Reaction equation M h c + M nadph c + M q c )−−−−* M nadp c + M qh2 c (1739)

Reactants

Table 1657: Properties of each reactant. Id Name SBO M h c H+ M nadph c Nicotinamide adenine dinucleotide phosphate - reduced M q c Ubiquinone

Products

Produced by SBML2LATEX 743 Table 1658: Properties of each product. Id Name SBO M nadp c Nicotinamide adenine dinucleotide phosphate M qh2 c Ubiquinol

Kinetic Law

v870 = not speciﬁed (1740)

6.871 Reaction R QULNS This is an irreversible reaction of two reactants forming three products.

Name quinolinate synthase

Reaction equation M dhap c + M iasp c −→ 2M h2o c + M pi c + M quln c (1741)

Reactants

Table 1659: Properties of each reactant. Id Name SBO M dhap c Dihydroxyacetone phosphate M iasp c Iminoaspartate

Products

Table 1660: Properties of each product. Id Name SBO M h2o c H2O M pi c Phosphate M quln c Quinolinate

Kinetic Law

v871 = not speciﬁed (1742)

744 Produced by SBML2LATEX 6.872 Reaction R R05217 This is an irreversible reaction of three reactants forming one product.

Name Precorrin 3A + Oxygen <=> Precorrin 3B

Reaction equation M h c + 0·5M o2 c + M pre3a c −→ M pre3b c (1743)

Reactants

Table 1661: Properties of each reactant. Id Name SBO M h c H+ M o2 c O2 M pre3a c Precorrin 3 A

Product

Table 1662: Properties of each product. Id Name SBO M pre3b c Precorrin 3B

Kinetic Law

v872 = not speciﬁed (1744)

6.873 Reaction R R05219 This is an irreversible reaction of three reactants forming four products.

Name Precorrin 5 <=> Precorrin 6X

Reaction equation M amet c + M h2o c + M pre5 c −→ M ac c + M ahcys c + M h c + M pre6a c (1745)

Reactants

Produced by SBML2LATEX 745 Table 1663: Properties of each reactant. Id Name SBO M amet c S-Adenosyl-L-methionine M h2o c H2O M pre5 c Precorrin 5

Products

Table 1664: Properties of each product. Id Name SBO M ac c Acetate M ahcys c S-Adenosyl-L-homocysteine M h c H+ M pre6a c Precorrin 6A

Kinetic Law

v873 = not speciﬁed (1746)

6.874 Reaction R R05224 This is an irreversible reaction of four reactants forming ﬁve products.

Name Hydrogenobyrinate <=> Hydrogenobyrinate a,c diamide

Reaction equation 2M atp c + 2M gln DASH L c + M h2o c + M hgbyr c −→ 2M adp c + 2M glu DASH L c + M h c + M hgbam c + M ppi c (1747)

Reactants

Table 1665: Properties of each reactant. Id Name SBO M atp c ATP M gln DASH L c L-Glutamine M h2o c H2O M hgbyr c Hydrogenobyrinate

746 Produced by SBML2LATEX Products

Table 1666: Properties of each product. Id Name SBO M adp c ADP M glu DASH L c L-Glutamate M h c H+ M hgbam c Hydrogenobyrinate a,c diamide M ppi c Diphosphate

Kinetic Law

v874 = not speciﬁed (1748)

6.875 Reaction R RBFK This is an irreversible reaction of two reactants forming three products.

Name riboﬂavin kinase

Reaction equation M atp c + M ribﬂv c −→ M adp c + M fmn c + M h c (1749)

Reactants

Table 1667: Properties of each reactant. Id Name SBO M atp c ATP M ribflv c Riboﬂavin

Products

Table 1668: Properties of each product. Id Name SBO M adp c ADP M fmn c FMN M h c H+

Produced by SBML2LATEX 747 Kinetic Law

v875 = not speciﬁed (1750)

6.876 Reaction R RBFSa This is an irreversible reaction of two reactants forming three products.

Name riboﬂavin synthase

Reaction equation M 4r5au c + M db4p c −→ M dmlz c + 2M h2o c + M pi c (1751)

Reactants

Table 1669: Properties of each reactant. Id Name SBO M 4r5au c 4-(1-D-Ribitylamino)-5-aminouracil M db4p c 3,4-dihydroxy-2-butanone 4-phosphate

Products

Table 1670: Properties of each product. Id Name SBO M dmlz c 6,7-Dimethyl-8-(1-D-ribityl)lumazine M h2o c H2O M pi c Phosphate

Kinetic Law

v876 = not speciﬁed (1752)

6.877 Reaction R RBFSb This is an irreversible reaction of one reactant forming two products.

Name riboﬂavin synthase

Reaction equation 2M dmlz c −→ M 4r5au c + M ribﬂv c (1753)

748 Produced by SBML2LATEX Reactant

Table 1671: Properties of each reactant. Id Name SBO M dmlz c 6,7-Dimethyl-8-(1-D-ribityl)lumazine

Products

Table 1672: Properties of each product. Id Name SBO M 4r5au c 4-(1-D-Ribitylamino)-5-aminouracil M ribflv c Riboﬂavin

Kinetic Law

v877 = not speciﬁed (1754)

6.878 Reaction R RBK This is an irreversible reaction of two reactants forming three products.

Name ribokinase

Reaction equation M atp c + M rib DASH D c −→ M adp c + M h c + M r5p c (1755)

Reactants

Table 1673: Properties of each reactant. Id Name SBO M atp c ATP M rib DASH D c D-Ribose

Products

Produced by SBML2LATEX 749 Table 1674: Properties of each product. Id Name SBO M adp c ADP M h c H+ M r5p c alpha-D-Ribose 5-phosphate

Kinetic Law

v878 = not speciﬁed (1756)

6.879 Reaction R RBK Dr This is a reversible reaction of two reactants forming three products.

Name D-ribulokinase (reversible)

Reaction equation M atp c + M rbl DASH D c −−)−−* M adp c + M h c + M ru5p DASH D c (1757)

Reactants

Table 1675: Properties of each reactant. Id Name SBO M atp c ATP M rbl DASH D c D-Ribulose

Products

Table 1676: Properties of each product. Id Name SBO M adp c ADP M h c H+ M ru5p DASH D c D-Ribulose 5-phosphate

Kinetic Law

v879 = not speciﬁed (1758)

750 Produced by SBML2LATEX 6.880 Reaction R RBK L1r This is a reversible reaction of two reactants forming three products.

Name L-ribulokinase (L-ribulose) (reversible)

Reaction equation M atp c + M rbl DASH L c −−)−−* M adp c + M h c + M ru5p DASH L c (1759)

Reactants

Table 1677: Properties of each reactant. Id Name SBO M atp c ATP M rbl DASH L c L-Ribulose

Products

Table 1678: Properties of each product. Id Name SBO M adp c ADP M h c H+ M ru5p DASH L c L-Ribulose 5-phosphate

Kinetic Law

v880 = not speciﬁed (1760)

6.881 Reaction R RIBabc This is an irreversible reaction of three reactants forming four products.

Name D-ribose transport via ABC system

Reaction equation M atp c + M h2o c + M rib DASH D e −→ M adp c + M h c + M pi c + M rib DASH D c (1761)

Reactants

Produced by SBML2LATEX 751 Table 1679: Properties of each reactant. Id Name SBO M atp c ATP M h2o c H2O M rib DASH D e D-Ribose

Products

Table 1680: Properties of each product. Id Name SBO M adp c ADP M h c H+ M pi c Phosphate M rib DASH D c D-Ribose

Kinetic Law

v881 = not speciﬁed (1762)

6.882 Reaction R RNDR1 This is an irreversible reaction of two reactants forming three products.

Name ribonucleoside-diphosphate reductase (ADP)

Reaction equation M adp c + M trdrd c −→ M dadp c + M h2o c + M trdox c (1763)

Reactants

Table 1681: Properties of each reactant. Id Name SBO M adp c ADP M trdrd c Reduced thioredoxin

Products

752 Produced by SBML2LATEX Table 1682: Properties of each product. Id Name SBO M dadp c dADP M h2o c H2O M trdox c Oxidized thioredoxin

Kinetic Law

v882 = not speciﬁed (1764)

6.883 Reaction R RNDR2 This is an irreversible reaction of two reactants forming three products.

Name ribonucleoside-diphosphate reductase (GDP)

Reaction equation M gdp c + M trdrd c −→ M dgdp c + M h2o c + M trdox c (1765)

Reactants

Table 1683: Properties of each reactant. Id Name SBO M gdp c GDP M trdrd c Reduced thioredoxin

Products

Table 1684: Properties of each product. Id Name SBO M dgdp c dGDP M h2o c H2O M trdox c Oxidized thioredoxin

Kinetic Law

v883 = not speciﬁed (1766)

Produced by SBML2LATEX 753 6.884 Reaction R RNDR3 This is an irreversible reaction of two reactants forming three products.

Name ribonucleoside-diphosphate reductase (CDP)

Reaction equation M cdp c + M trdrd c −→ M dcdp c + M h2o c + M trdox c (1767)

Reactants

Table 1685: Properties of each reactant. Id Name SBO M cdp c CDP M trdrd c Reduced thioredoxin

Products

Table 1686: Properties of each product. Id Name SBO M dcdp c dCDP M h2o c H2O M trdox c Oxidized thioredoxin

Kinetic Law

v884 = not speciﬁed (1768)

6.885 Reaction R RNDR4 This is an irreversible reaction of two reactants forming three products.

Name ribonucleoside-diphosphate reductase (UDP)

Reaction equation M trdrd c + M udp c −→ M dudp c + M h2o c + M trdox c (1769)

Reactants

754 Produced by SBML2LATEX Table 1687: Properties of each reactant. Id Name SBO M trdrd c Reduced thioredoxin M udp c UDP

Products

Table 1688: Properties of each product. Id Name SBO M dudp c dUDP M h2o c H2O M trdox c Oxidized thioredoxin

Kinetic Law

v885 = not speciﬁed (1770)

6.886 Reaction R RNTR4 This is an irreversible reaction of two reactants forming three products.

Name ribonucleoside-triphosphate reductase (UTP)

Reaction equation M trdrd c + M utp c −→ M dutp c + M h2o c + M trdox c (1771)

Reactants

Table 1689: Properties of each reactant. Id Name SBO M trdrd c Reduced thioredoxin M utp c UTP

Products

Produced by SBML2LATEX 755 Table 1690: Properties of each product. Id Name SBO M dutp c dUTP M h2o c H2O M trdox c Oxidized thioredoxin

Kinetic Law

v886 = not speciﬁed (1772)

6.887 Reaction R RPE This is a reversible reaction of one reactant forming one product.

Name ribulose 5-phosphate 3-epimerase

Reaction equation M ru5p DASH D c )−−−−* M xu5p DASH D c (1773)

Reactant

Table 1691: Properties of each reactant. Id Name SBO M ru5p DASH D c D-Ribulose 5-phosphate

Product

Table 1692: Properties of each product. Id Name SBO M xu5p DASH D c D-Xylulose 5-phosphate

Kinetic Law

v887 = not speciﬁed (1774)

6.888 Reaction R RPI This is a reversible reaction of one reactant forming one product.

756 Produced by SBML2LATEX Name ribose-5-phosphate isomerase

Reaction equation M r5p c )−−−−* M ru5p DASH D c (1775)

Reactant

Table 1693: Properties of each reactant. Id Name SBO M r5p c alpha-D-Ribose 5-phosphate

Product

Table 1694: Properties of each product. Id Name SBO M ru5p DASH D c D-Ribulose 5-phosphate

Kinetic Law

v888 = not speciﬁed (1776)

6.889 Reaction R RPPDIMAS This is an irreversible reaction of two reactants forming three products.

Name rhamnose phenol phthiocerol dimycocerosate synthesis

Reaction equation M dtdprmn c + M ppdima c −→ M dtdp c + M h c + M rppdima c (1777)

Reactants

Table 1695: Properties of each reactant. Id Name SBO M dtdprmn c dTDP-L-rhamnose M ppdima c phenol phthiocerol dimycocerosate (Mtb)

Produced by SBML2LATEX 757 Products

Table 1696: Properties of each product. Id Name SBO M dtdp c dTDP M h c H+ M rppdima c rhamnose phenol phthiocerol dimycocerosate (Mtb)

Kinetic Law

v889 = not speciﬁed (1778)

6.890 Reaction R RRPPDIMAS This is an irreversible reaction of two reactants forming three products.

Name rhamnose rhamnose phenol phthiocerol dimycocerosate synthesis

Reaction equation M dtdprmn c + M rppdima c −→ M dtdp c + M h c + M rrppdima c (1779)

Reactants

Table 1697: Properties of each reactant. Id Name SBO M dtdprmn c dTDP-L-rhamnose M rppdima c rhamnose phenol phthiocerol dimycocerosate (Mtb)

Products

Table 1698: Properties of each product. Id Name SBO M dtdp c dTDP M h c H+ M rrppdima c rhamnose rhamnose phenol phthiocerol dimycocerosate (Mtb)

758 Produced by SBML2LATEX Kinetic Law

v890 = not speciﬁed (1780)

6.891 Reaction R RZ5PP This is an irreversible reaction of two reactants forming two products.

Name alpha-ribazole 5-phosphate phosphatase

Reaction equation M 5prdmbz c + M h2o c −→ M pi c + M rdmbzi c (1781)

Reactants

Table 1699: Properties of each reactant. Id Name SBO M 5prdmbz c N1-(5-Phospho-alpha-D-ribosyl)-5,6-dimethylbenzimidazole M h2o c H2O

Products

Table 1700: Properties of each product. Id Name SBO M pi c Phosphate M rdmbzi c N1-(alpha-D-ribosyl)-5,6-dimethylbenzimidazole

Kinetic Law

v891 = not speciﬁed (1782)

6.892 Reaction R SADH This is an irreversible reaction of three reactants forming three products.

Name Succinylarginine dihydrolase

Reaction equation 2M h2o c + 2M h c + M sucarg c −→ M co2 c + 2M nh4 c + M sucorn c (1783)

Produced by SBML2LATEX 759 Reactants

Table 1701: Properties of each reactant. Id Name SBO M h2o c H2O M h c H+ M sucarg c N2-Succinyl-L-arginine

Products

Table 1702: Properties of each product. Id Name SBO M co2 c CO2 M nh4 c Ammonium M sucorn c N2-Succinyl-L-ornithine

Kinetic Law

v892 = not speciﬁed (1784)

6.893 Reaction R SADT This is an irreversible reaction of three reactants forming two products.

Name sulfate adenylyltransferase

Reaction equation M atp c + M h c + M so4 c −→ M aps c + M ppi c (1785)

Reactants

Table 1703: Properties of each reactant. Id Name SBO M atp c ATP M h c H+ M so4 c Sulfate

760 Produced by SBML2LATEX Products

Table 1704: Properties of each product. Id Name SBO M aps c Adenosine 5’-phosphosulfate M ppi c Diphosphate

Kinetic Law

v893 = not speciﬁed (1786)

6.894 Reaction R SADT2 This is an irreversible reaction of four reactants forming four products.

Name Sulfate adenyltransferase

Reaction equation M atp c + M gtp c + M h2o c + M so4 c −→ M aps c + M gdp c + M pi c + M ppi c (1787)

Reactants

Table 1705: Properties of each reactant. Id Name SBO M atp c ATP M gtp c GTP M h2o c H2O M so4 c Sulfate

Products

Table 1706: Properties of each product. Id Name SBO M aps c Adenosine 5’-phosphosulfate M gdp c GDP M pi c Phosphate M ppi c Diphosphate

Produced by SBML2LATEX 761 Kinetic Law

v894 = not speciﬁed (1788)

6.895 Reaction R SALCS This is an irreversible reaction of one reactant forming two products.

Name salicylate synthase

Reaction equation M chor c −→ M pyr c + M salc c (1789)

Reactant

Table 1707: Properties of each reactant. Id Name SBO M chor c chorismate

Products

Table 1708: Properties of each product. Id Name SBO M pyr c Pyruvate M salc c Salicylate

Kinetic Law

v895 = not speciﬁed (1790)

6.896 Reaction R SDPDS This is an irreversible reaction of two reactants forming two products.

Name succinyl-diaminopimelate desuccinylase

Reaction equation

M h2o c + M sl26da c −→ M 26dap DASH LL c + M succ c (1791)

762 Produced by SBML2LATEX Reactants

Produced by SBML2LATEX 763 Table 1709: Properties of each reactant. Id Name SBO M h2o c H2O M sl26da c N-Succinyl-LL-2,6-diaminoheptanedioate

Products

Table 1710: Properties of each product. Id Name SBO M 26dap DASH LL c LL-2,6-Diaminoheptanedioate M succ c Succinate

Kinetic Law

v896 = not speciﬁed (1792)

6.897 Reaction R SDPTA This is a reversible reaction of two reactants forming two products.

Name succinyldiaminopimelate transaminase

Reaction equation M akg c + M sl26da c )−−−−* M glu DASH L c + M sl2a6o c (1793)

Reactants

Table 1711: Properties of each reactant. Id Name SBO M akg c 2-Oxoglutarate M sl26da c N-Succinyl-LL-2,6-diaminoheptanedioate

Products

Table 1712: Properties of each product. Id Name SBO M glu DASH L c L-Glutamate

764 Produced by SBML2LATEX Id Name SBO M sl2a6o c N-Succinyl-2-L-amino-6-oxoheptanedioate

Kinetic Law

v897 = not speciﬁed (1794)

6.898 Reaction R SELCYSLY This is an irreversible reaction of two reactants forming four products.

Name selenocysteine lyase

Reaction equation M dtt c + M selcys c −→ M ala DASH L c + M dttOX c + M h c + M seln c (1795)

Reactants

Table 1713: Properties of each reactant. Id Name SBO M dtt c Dithiothreitol M selcys c Selenocysteine

Products

Table 1714: Properties of each product. Id Name SBO M ala DASH L c L-Alanine M dttOX c Oxidized dithiothreitol M h c H+ M seln c Selenide

Kinetic Law

v898 = not speciﬁed (1796)

6.899 Reaction R SERAT This is a reversible reaction of two reactants forming two products.

Produced by SBML2LATEX 765 Name serine O-acetyltransferase

Reaction equation M accoa c + M ser DASH L c )−−−−* M acser c + M coa c (1797)

Reactants

Table 1715: Properties of each reactant. Id Name SBO M accoa c Acetyl-CoA M ser DASH L c L-Serine

Products

Table 1716: Properties of each product. Id Name SBO M acser c O-Acetyl-L-serine M coa c Coenzyme A

Kinetic Law

v899 = not speciﬁed (1798)

6.900 Reaction R SERD D This is an irreversible reaction of one reactant forming two products.

Name D-serine deaminase

Reaction equation M ser DASH D c −→ M nh4 c + M pyr c (1799)

Reactant

Table 1717: Properties of each reactant. Id Name SBO M ser DASH D c D-Serine

766 Produced by SBML2LATEX Products

Table 1718: Properties of each product. Id Name SBO M nh4 c Ammonium M pyr c Pyruvate

Kinetic Law

v900 = not speciﬁed (1800)

6.901 Reaction R SERD L This is an irreversible reaction of one reactant forming two products.

Name L-serine deaminase

Reaction equation M ser DASH L c −→ M nh4 c + M pyr c (1801)

Reactant

Table 1719: Properties of each reactant. Id Name SBO M ser DASH L c L-Serine

Products

Table 1720: Properties of each product. Id Name SBO M nh4 c Ammonium M pyr c Pyruvate

Kinetic Law

v901 = not speciﬁed (1802)

Produced by SBML2LATEX 767 6.902 Reaction R SERt2r This is a reversible reaction of two reactants forming two products.

Name L-serine reversible transport via proton symport

Reaction equation M h e + M ser DASH L e )−−−−* M h c + M ser DASH L c (1803)

Reactants

Table 1721: Properties of each reactant. Id Name SBO M h e H+ M ser DASH L e L-Serine

Products

Table 1722: Properties of each product. Id Name SBO M h c H+ M ser DASH L c L-Serine

Kinetic Law

v902 = not speciﬁed (1804)

6.903 Reaction R SGDS This is an irreversible reaction of two reactants forming two products.

Name Succinylglutamate desuccinylase

Reaction equation M h2o c + M sucglu c −→ M glu DASH L c + M succ c (1805)

Reactants

768 Produced by SBML2LATEX Table 1723: Properties of each reactant. Id Name SBO M h2o c H2O M sucglu c N2-Succinyl-L-glutamate

Products

Table 1724: Properties of each product. Id Name SBO M glu DASH L c L-Glutamate M succ c Succinate

Kinetic Law

v903 = not speciﬁed (1806)

6.904 Reaction R SGSAD This is an irreversible reaction of three reactants forming three products.

Name Succinylglutamic semialdehyde dehydrogenase

Reaction equation M h2o c + M nad c + M sucgsa c −→ 2M h c + M nadh c + M sucglu c (1807)

Reactants

Table 1725: Properties of each reactant. Id Name SBO M h2o c H2O M nad c Nicotinamide adenine dinucleotide M sucgsa c N2-Succinyl-L-glutamate 5-semialdehyde

Products

Produced by SBML2LATEX 769 Table 1726: Properties of each product. Id Name SBO M h c H+ M nadh c Nicotinamide adenine dinucleotide - reduced M sucglu c N2-Succinyl-L-glutamate

Kinetic Law

v904 = not speciﬁed (1808)

6.905 Reaction R SHCHCS This is an irreversible reaction of two reactants forming two products.

Name 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase

Reaction equation M ichor c + M sucsal c −→ M 2shchc c + M pyr c (1809)

Reactants

Table 1727: Properties of each reactant. Id Name SBO M ichor c Isochorismate M sucsal c Succinic semialdehyde

Products

Table 1728: Properties of each product. Id Name SBO M 2shchc c 2-Succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate M pyr c Pyruvate

Kinetic Law

v905 = not speciﬁed (1810)

770 Produced by SBML2LATEX 6.906 Reaction R SHCHCS2 This is an irreversible reaction of two reactants forming three products.

Name 2-succinyl-6-hydroxy-2,4-cyclohexadiene 1-carboxylate synthase

Reaction equation M ichor c + M ssaltpp c −→ M 2shchc c + M pyr c + M thmpp c (1811)

Reactants

Table 1729: Properties of each reactant. Id Name SBO M ichor c Isochorismate M ssaltpp c Succinate semialdehyde-thiamin diphosphate anion

Products

Table 1730: Properties of each product. Id Name SBO M 2shchc c 2-Succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate M pyr c Pyruvate M thmpp c Thiamine diphosphate

Kinetic Law

v906 = not speciﬁed (1812)

6.907 Reaction R SHCHD2 This is an irreversible reaction of two reactants forming three products.

Name sirohydrochlorin dehydrogenase (NAD)

Reaction equation M dscl c + M nad c −→ M h c + M nadh c + M scl c (1813)

Reactants

Produced by SBML2LATEX 771 Table 1731: Properties of each reactant. Id Name SBO M dscl c dihydrosirohydrochlorin M nad c Nicotinamide adenine dinucleotide

Products

Table 1732: Properties of each product. Id Name SBO M h c H+ M nadh c Nicotinamide adenine dinucleotide - reduced M scl c sirohydrochlorin

Kinetic Law

v907 = not speciﬁed (1814)

6.908 Reaction R SHCHD3 This is an irreversible reaction of two reactants forming three products.

Name sirohydrochlorin dehydrogenase (NAD)

Reaction equation M nad c + M pre2 c −→ M h c + M nadh c + M scl2 c (1815)

Reactants

Table 1733: Properties of each reactant. Id Name SBO M nad c Nicotinamide adenine dinucleotide M pre2 c dihydrosirohydrochlorin

Products

772 Produced by SBML2LATEX Table 1734: Properties of each product. Id Name SBO M h c H+ M nadh c Nicotinamide adenine dinucleotide - reduced M scl2 c sirohydrochlorin 2

Kinetic Law

v908 = not speciﬁed (1816)

6.909 Reaction R SHCHF This is an irreversible reaction of two reactants forming two products.

Name sirohydrochlorin ferrochelatase

Reaction equation M fe2 c + M scl c −→ 3M h c + M sheme c (1817)

Reactants

Table 1735: Properties of each reactant. Id Name SBO M fe2 c Fe2+ M scl c sirohydrochlorin

Products

Table 1736: Properties of each product. Id Name SBO M h c H+ M sheme c Siroheme

Kinetic Law

v909 = not speciﬁed (1818)

Produced by SBML2LATEX 773 6.910 Reaction R SHCHF2 This is an irreversible reaction of two reactants forming two products.

Name sirohydrochlorin ferrochelatase

Reaction equation M fe2 c + M scl2 c −→ 2M h c + M sheme c (1819)

Reactants

Table 1737: Properties of each reactant. Id Name SBO M fe2 c Fe2+ M scl2 c sirohydrochlorin 2

Products

Table 1738: Properties of each product. Id Name SBO M h c H+ M sheme c Siroheme

Kinetic Law

v910 = not speciﬁed (1820)

6.911 Reaction R SHCHF3 This is an irreversible reaction of two reactants forming three products.

Name sirohydrochlorin ferrochelatase (mycobactin)

Reaction equation M fmcbtt c + M scl c −→ 3M h c + M mcbtt c + M sheme c (1821)

Reactants

774 Produced by SBML2LATEX Table 1739: Properties of each reactant. Id Name SBO M fmcbtt c Iron(II) mycobactin T M scl c sirohydrochlorin

Products

Table 1740: Properties of each product. Id Name SBO M h c H+ M mcbtt c mycobactin T M sheme c Siroheme

Kinetic Law

v911 = not speciﬁed (1822)

6.912 Reaction R SHK3Dr This is a reversible reaction of three reactants forming two products.

Name shikimate dehydrogenase

Reaction equation M 3dhsk c + M h c + M nadph c )−−−−* M nadp c + M skm c (1823)

Reactants

Table 1741: Properties of each reactant. Id Name SBO M 3dhsk c 3-Dehydroshikimate M h c H+ M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

Products

Produced by SBML2LATEX 775 Table 1742: Properties of each product. Id Name SBO M nadp c Nicotinamide adenine dinucleotide phosphate M skm c Shikimate

Kinetic Law

v912 = not speciﬁed (1824)

6.913 Reaction R SHKK This is an irreversible reaction of two reactants forming three products.

Name shikimate kinase

Reaction equation M atp c + M skm c −→ M adp c + M h c + M skm5p c (1825)

Reactants

Table 1743: Properties of each reactant. Id Name SBO M atp c ATP M skm c Shikimate

Products

Table 1744: Properties of each product. Id Name SBO M adp c ADP M h c H+ M skm5p c Shikimate 5-phosphate

Kinetic Law

v913 = not speciﬁed (1826)

776 Produced by SBML2LATEX 6.914 Reaction R SHSL1r This is a reversible reaction of two reactants forming three products.

Name O-succinylhomoserine lyase reversible

Reaction equation M cys DASH L c + M suchms c )−−−−* M cyst DASH L c + M h c + M succ c (1827)

Reactants

Table 1745: Properties of each reactant. Id Name SBO M cys DASH L c L-Cysteine M suchms c O-Succinyl-L-homoserine

Products

Table 1746: Properties of each product. Id Name SBO M cyst DASH L c L-Cystathionine M h c H+ M succ c Succinate

Kinetic Law

v914 = not speciﬁed (1828)

6.915 Reaction R SHSL4r This is a reversible reaction of two reactants forming four products.

Name O-succinylhomoserine lyase (elimination), reversible

Reaction equation M h2o c + M suchms c )−−−−* M 2obut c + M h c + M nh4 c + M succ c (1829)

Reactants

Produced by SBML2LATEX 777 Table 1747: Properties of each reactant. Id Name SBO M h2o c H2O M suchms c O-Succinyl-L-homoserine

Products

Table 1748: Properties of each product. Id Name SBO M 2obut c 2-Oxobutanoate M h c H+ M nh4 c Ammonium M succ c Succinate

Kinetic Law

v915 = not speciﬁed (1830)

6.916 Reaction R SKMt2 This is a reversible reaction of two reactants forming two products.

Name shikimate transport in via proton symport

Reaction equation M h e + M skm e )−−−−* M h c + M skm c (1831)

Reactants

Table 1749: Properties of each reactant. Id Name SBO M h e H+ M skm e Shikimate

Products

778 Produced by SBML2LATEX Table 1750: Properties of each product. Id Name SBO M h c H+ M skm c Shikimate

Kinetic Law

v916 = not speciﬁed (1832)

6.917 Reaction R SOTA This is an irreversible reaction of two reactants forming two products.

Name Succinylornithine transaminase

Reaction equation M akg c + M sucorn c −→ M glu DASH L c + M sucgsa c (1833)

Reactants

Table 1751: Properties of each reactant. Id Name SBO M akg c 2-Oxoglutarate M sucorn c N2-Succinyl-L-ornithine

Products

Table 1752: Properties of each product. Id Name SBO M glu DASH L c L-Glutamate M sucgsa c N2-Succinyl-L-glutamate 5-semialdehyde

Kinetic Law

v917 = not speciﬁed (1834)

6.918 Reaction R SPMS This is an irreversible reaction of two reactants forming three products.

Produced by SBML2LATEX 779 Name spermidine synthase

Reaction equation M ametam c + M ptrc c −→ M 5mta c + M h c + M spmd c (1835)

Reactants

Table 1753: Properties of each reactant. Id Name SBO M ametam c S-Adenosylmethioninamine M ptrc c Putrescine

Products

Table 1754: Properties of each product. Id Name SBO M 5mta c 5-Methylthioadenosine M h c H+ M spmd c Spermidine

Kinetic Law

v918 = not speciﬁed (1836)

6.919 Reaction R SPODM This is an irreversible reaction of two reactants forming two products.

Name superoxide dismutase

Reaction equation 2M h c + 2M o2s c −→ M h2o2 c + M o2 c (1837)

Reactants

780 Produced by SBML2LATEX Table 1755: Properties of each reactant. Id Name SBO M h c H+ M o2s c Superoxide anion

Products

Table 1756: Properties of each product. Id Name SBO M h2o2 c Hydrogen peroxide M o2 c O2

Kinetic Law

v919 = not speciﬁed (1838)

6.920 Reaction R SSALx This is an irreversible reaction of three reactants forming three products.

Name succinate-semialdehyde dehydrogenase (NAD)

Reaction equation M h2o c + M nad c + M sucsal c −→ 2M h c + M nadh c + M succ c (1839)

Reactants

Table 1757: Properties of each reactant. Id Name SBO M h2o c H2O M nad c Nicotinamide adenine dinucleotide M sucsal c Succinic semialdehyde

Products

Produced by SBML2LATEX 781 Table 1758: Properties of each product. Id Name SBO M h c H+ M nadh c Nicotinamide adenine dinucleotide - reduced M succ c Succinate

Kinetic Law

v920 = not speciﬁed (1840)

6.921 Reaction R SSALy This is an irreversible reaction of three reactants forming three products.

Name succinate-semialdehyde dehydrogenase (NADP)

Reaction equation M h2o c + M nadp c + M sucsal c −→ 2M h c + M nadph c + M succ c (1841)

Reactants

Table 1759: Properties of each reactant. Id Name SBO M h2o c H2O M nadp c Nicotinamide adenine dinucleotide phosphate M sucsal c Succinic semialdehyde

Products

Table 1760: Properties of each product. Id Name SBO M h c H+ M nadph c Nicotinamide adenine dinucleotide phosphate - reduced M succ c Succinate

Kinetic Law

v921 = not speciﬁed (1842)

782 Produced by SBML2LATEX 6.922 Reaction R SUCBZL This is an irreversible reaction of three reactants forming three products.

Name o-succinylbenzoate-CoA ligase

Reaction equation M atp c + M coa c + M sucbz c −→ M amp c + M ppi c + M sbzcoa c (1843)

Reactants

Table 1761: Properties of each reactant. Id Name SBO M atp c ATP M coa c Coenzyme A M sucbz c o-Succinylbenzoate

Products

Table 1762: Properties of each product. Id Name SBO M amp c AMP M ppi c Diphosphate M sbzcoa c O-Succinylbenzoyl-CoA

Kinetic Law

v922 = not speciﬁed (1844)

6.923 Reaction R SUCBZS This is an irreversible reaction of one reactant forming two products.

Name O-succinylbenzoate-CoA synthase

Reaction equation M 2shchc c −→ M h2o c + M sucbz c (1845)

Reactant

Produced by SBML2LATEX 783 Table 1763: Properties of each reactant. Id Name SBO M 2shchc c 2-Succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate

Products

Table 1764: Properties of each product. Id Name SBO M h2o c H2O M sucbz c o-Succinylbenzoate

Kinetic Law

v923 = not speciﬁed (1846)

6.924 Reaction R SUCCt2r This is a reversible reaction of two reactants forming two products.

Name succinate transport via proton symport

Reaction equation M h e + M succ e )−−−−* M h c + M succ c (1847)

Reactants

Table 1765: Properties of each reactant. Id Name SBO M h e H+ M succ e Succinate

Products

Table 1766: Properties of each product. Id Name SBO M h c H+ M succ c Succinate

784 Produced by SBML2LATEX Id Name SBO

Kinetic Law

v924 = not speciﬁed (1848)

6.925 Reaction R SUCD1i This is an irreversible reaction of two reactants forming two products.

Name succinate dehydrogenase

Reaction equation M fad c + M succ c −→ M fadh2 c + M fum c (1849)

Reactants

Table 1767: Properties of each reactant. Id Name SBO M fad c Flavin adenine dinucleotide oxidized M succ c Succinate

Products

Table 1768: Properties of each product. Id Name SBO M fadh2 c Flavin adenine dinucleotide reduced M fum c Fumarate

Kinetic Law

v925 = not speciﬁed (1850)

6.926 Reaction R SUCOAS This is a reversible reaction of three reactants forming three products.

Name succinyl-CoA synthetase (ADP-forming)

Produced by SBML2LATEX 785 Reaction equation M atp c + M coa c + M succ c )−−−−* M adp c + M pi c + M succoa c (1851)

Reactants

Table 1769: Properties of each reactant. Id Name SBO M atp c ATP M coa c Coenzyme A M succ c Succinate

Products

Table 1770: Properties of each product. Id Name SBO M adp c ADP M pi c Phosphate M succoa c Succinyl-CoA

Kinetic Law

v926 = not speciﬁed (1852)

6.927 Reaction R SULR This is a reversible reaction of three reactants forming three products.

Name sulﬁte reductase (NADPH2)

Reaction equation 3M h2o c + M h2s c + 3M nadp c )−−−−* 5M h c + 3M nadph c + M so3 c (1853)

Reactants

Table 1771: Properties of each reactant. Id Name SBO M h2o c H2O

786 Produced by SBML2LATEX Id Name SBO M h2s c Hydrogen sulﬁde M nadp c Nicotinamide adenine dinucleotide phosphate

Products

Table 1772: Properties of each product. Id Name SBO M h c H+ M nadph c Nicotinamide adenine dinucleotide phosphate - reduced M so3 c Sulﬁte

Kinetic Law

v927 = not speciﬁed (1854)

6.928 Reaction R SULabc This is an irreversible reaction of three reactants forming four products.

Name sulfate transport via ABC system

Reaction equation M atp c + M h2o c + M so4 e −→ M adp c + M h c + M pi c + M so4 c (1855)

Reactants

Table 1773: Properties of each reactant. Id Name SBO M atp c ATP M h2o c H2O M so4 e Sulfate

Products

Produced by SBML2LATEX 787 Table 1774: Properties of each product. Id Name SBO M adp c ADP M h c H+ M pi c Phosphate M so4 c Sulfate

Kinetic Law

v928 = not speciﬁed (1856)

6.929 Reaction R TALA This is a reversible reaction of two reactants forming two products.

Name transaldolase

Reaction equation M g3p c + M s7p c )−−−−* M e4p c + M f6p c (1857)

Reactants

Table 1775: Properties of each reactant. Id Name SBO M g3p c Glyceraldehyde 3-phosphate M s7p c Sedoheptulose 7-phosphate

Products

Table 1776: Properties of each product. Id Name SBO M e4p c D-Erythrose 4-phosphate M f6p c D-Fructose 6-phosphate

Kinetic Law

v929 = not speciﬁed (1858)

788 Produced by SBML2LATEX 6.930 Reaction R TARTD This is an irreversible reaction of one reactant forming two products.

Name L(+)-tartrate dehydratase

Reaction equation M tartr DASH L c −→ M h2o c + M oaa c (1859)

Reactant

Table 1777: Properties of each reactant. Id Name SBO M tartr DASH L c L-tartrate

Products

Table 1778: Properties of each product. Id Name SBO M h2o c H2O M oaa c Oxaloacetate

Kinetic Law

v930 = not speciﬁed (1860)

6.931 Reaction R TARTRt7 This is a reversible reaction of two reactants forming two products.

Name Tartrate/succinate antiporter

Reaction equation M succ c + M tartr DASH L e )−−−−* M succ e + M tartr DASH L c (1861)

Reactants

Produced by SBML2LATEX 789 Table 1779: Properties of each reactant. Id Name SBO M succ c Succinate M tartr DASH L e L-tartrate

Products

Table 1780: Properties of each product. Id Name SBO M succ e Succinate M tartr DASH L c L-tartrate

Kinetic Law

v931 = not speciﬁed (1862)

6.932 Reaction R TAS This is an irreversible reaction of two reactants forming two products.

Name tetra-arabinofuranoside synthesis

Reaction equation M arab DASH D c + 3M decda tb c −→ 3M decd tb c + M tarab DASH D c (1863)

Reactants

Table 1781: Properties of each reactant. Id Name SBO M arab DASH D c D-Arabinose M decda tb c decaprenylphosphoryl-beta-D-arabinofuranose

Products

Table 1782: Properties of each product. Id Name SBO M decd tb c (E,E,E,E,E,E,E,Z,Z) decaprenyl phosphate

790 Produced by SBML2LATEX Id Name SBO M tarab DASH D c tetra-arabinofuranoside

Kinetic Law

v932 = not speciﬁed (1864)

6.933 Reaction R TATS This is an irreversible reaction of ﬁve reactants forming two products.

Name tetra-acyl trehalose synthesis

Reaction equation 4M h c + M hdca c + M hpmtria c + 2M omtta c + M tre c −→ 4M h2o c + M tat c (1865)

Reactants

Table 1783: Properties of each reactant. Id Name SBO M h c H+ M hdca c Hexadecanoate (n-C16:0) M hpmtria c hepta-methyl triacontanoic acid (C30:0, plus 7 methyl branches) M omtta c octa-methyl tetracontatricosanoic acid (C34:0, 8 methyl-branched carbons) M tre c Trehalose

Products

Table 1784: Properties of each product. Id Name SBO M h2o c H2O M tat c tetra-acyl trehalose

Kinetic Law

v933 = not speciﬁed (1866)

Produced by SBML2LATEX 791 6.934 Reaction R TATSO This is an irreversible reaction of ﬁve reactants forming two products.

Name tetra-acyl trehalose sulfate (sulfolipid-1) synthesis

Reaction equation 4M h c + M hdca c + M hpmtria c + 2M omtta c + M tres c −→ 4M h2o c + M sl1 c (1867)

Reactants

Table 1785: Properties of each reactant. Id Name SBO M h c H+ M hdca c Hexadecanoate (n-C16:0) M hpmtria c hepta-methyl triacontanoic acid (C30:0, plus 7 methyl branches) M omtta c octa-methyl tetracontatricosanoic acid (C34:0, 8 methyl-branched carbons) M tres c trehalose 2 sulfate

Products

Table 1786: Properties of each product. Id Name SBO M h2o c H2O M sl1 c sulfonated tetra-acyl trehalose

Kinetic Law

v934 = not speciﬁed (1868)

6.935 Reaction R TDMS1 This is an irreversible reaction of four reactants forming two products.

Name trehalose dimycolate synthesis

Reaction equation 2M h c + M mmycolate c + M mycolate c + M tre c −→ 2M h2o c + M tdm1 c (1869)

792 Produced by SBML2LATEX Reactants

Table 1787: Properties of each reactant. Id Name SBO M h c H+ M mmycolate c methoxy mycolate (2 cyclopropanated rings) M mycolate c mycolate (2 cyclopropanated rings) M tre c Trehalose

Products

Table 1788: Properties of each product. Id Name SBO M h2o c H2O M tdm1 c trehalose dimycolate (alpha mycolate + methoxymycolate)

Kinetic Law

v935 = not speciﬁed (1870)

6.936 Reaction R TDMS2 This is an irreversible reaction of four reactants forming two products.

Name trehalose dimycolate synthesis

Reaction equation 2M h c + M mmmycolate c + M mycolate c + M tre c −→ 2M h2o c + M tdm2 c (1871)

Reactants

Table 1789: Properties of each reactant. Id Name SBO M h c H+ M mmmycolate c methoxy mycolate (1 cyclopropanated ring) M mycolate c mycolate (2 cyclopropanated rings) M tre c Trehalose

Produced by SBML2LATEX 793 Products

Table 1790: Properties of each product. Id Name SBO M h2o c H2O M tdm2 c trehalose dimycolate (alpha mycolate + methoxymycolate)

Kinetic Law

v936 = not speciﬁed (1872)

6.937 Reaction R TDMS3 This is an irreversible reaction of four reactants forming two products.

Name trehalose dimycolate synthesis

Reaction equation 2M h c + M mkmycolate c + M mycolate c + M tre c −→ 2M h2o c + M tdm3 c (1873)

Reactants

Table 1791: Properties of each reactant. Id Name SBO M h c H+ M mkmycolate c keto mycolate (1 cyclopropanated rings) M mycolate c mycolate (2 cyclopropanated rings) M tre c Trehalose

Products

Table 1792: Properties of each product. Id Name SBO M h2o c H2O M tdm3 c trehalose dimycolate (alpha mycolate + ketomycolate)

794 Produced by SBML2LATEX Kinetic Law

v937 = not speciﬁed (1874)

6.938 Reaction R TDMS4 This is an irreversible reaction of four reactants forming two products.

Name trehalose dimycolate synthesis

Reaction equation 2M h c + M kmycolate c + M mycolate c + M tre c −→ 2M h2o c + M tdm4 c (1875)

Reactants

Table 1793: Properties of each reactant. Id Name SBO M h c H+ M kmycolate c keto mycolate (2 cyclopropanated rings) M mycolate c mycolate (2 cyclopropanated rings) M tre c Trehalose

Products

Table 1794: Properties of each product. Id Name SBO M h2o c H2O M tdm4 c trehalose dimycolate (alpha mycolate + methoxymycolate)

Kinetic Law

v938 = not speciﬁed (1876)

6.939 Reaction R TDPDRE

This is an irreversible reaction of one reactant forming one product.

Name dTDP-4-dehydrorhamnose 3,5-epimerase

Produced by SBML2LATEX 795 Reaction equation M dtdp4d6dg c −→ M dtdp4d6dm c (1877)

Reactant

Table 1795: Properties of each reactant. Id Name SBO M dtdp4d6dg c dTDP-4-dehydro-6-deoxy-D-glucose

Product

Table 1796: Properties of each product. Id Name SBO M dtdp4d6dm c dTDP-4-dehydro-6-deoxy-L-mannose

Kinetic Law

v939 = not speciﬁed (1878)

6.940 Reaction R TDPDRR This is an irreversible reaction of three reactants forming two products.

Name dTDP-4-dehydrorhamnose reductase

Reaction equation M dtdp4d6dm c + M h c + M nadph c −→ M dtdprmn c + M nadp c (1879)

Reactants

Table 1797: Properties of each reactant. Id Name SBO M dtdp4d6dm c dTDP-4-dehydro-6-deoxy-L-mannose M h c H+ M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

796 Produced by SBML2LATEX Products

Table 1798: Properties of each product. Id Name SBO M dtdprmn c dTDP-L-rhamnose M nadp c Nicotinamide adenine dinucleotide phosphate

Kinetic Law

v940 = not speciﬁed (1880)

6.941 Reaction R TDPGDH This is an irreversible reaction of one reactant forming two products.

Name dTDPglucose 4,6-dehydratase

Reaction equation M dtdpglu c −→ M dtdp4d6dg c + M h2o c (1881)

Reactant

Table 1799: Properties of each reactant. Id Name SBO M dtdpglu c dTDPglucose

Products

Table 1800: Properties of each product. Id Name SBO M dtdp4d6dg c dTDP-4-dehydro-6-deoxy-D-glucose M h2o c H2O

Kinetic Law

v941 = not speciﬁed (1882)

Produced by SBML2LATEX 797 6.942 Reaction R THD1 This is a reversible reaction of two reactants forming two products.

Name NAD(P) transhydrogenase (B-speciﬁc)

Reaction equation M nad c + M nadph c )−−−−* M nadh c + M nadp c (1883)

Reactants

Table 1801: Properties of each reactant. Id Name SBO M nad c Nicotinamide adenine dinucleotide M nadph c Nicotinamide adenine dinucleotide phosphate - reduced

Products

Table 1802: Properties of each product. Id Name SBO M nadh c Nicotinamide adenine dinucleotide - reduced M nadp c Nicotinamide adenine dinucleotide phosphate

Kinetic Law

v942 = not speciﬁed (1884)

6.943 Reaction R THDPS This is an irreversible reaction of three reactants forming two products.

Name tetrahydrodipicolinate succinylase

Reaction equation M h2o c + M succoa c + M thdp c −→ M coa c + M sl2a6o c (1885)

Reactants

798 Produced by SBML2LATEX Table 1803: Properties of each reactant. Id Name SBO M h2o c H2O M succoa c Succinyl-CoA M thdp c 2,3,4,5-Tetrahydrodipicolinate

Products

Table 1804: Properties of each product. Id Name SBO M coa c Coenzyme A M sl2a6o c N-Succinyl-2-L-amino-6-oxoheptanedioate

Kinetic Law

v943 = not speciﬁed (1886)

6.944 Reaction R THFGLUS This is a reversible reaction of three reactants forming four products.

Name Tetrahydrofolate:L-glutamate gamma-ligase (ADP-forming)

Reaction equation M atp c + M glu DASH L c + M thf c )−−−−* M adp c + M h c + M pi c + M thfglu c (1887)

Reactants

Table 1805: Properties of each reactant. Id Name SBO M atp c ATP M glu DASH L c L-Glutamate M thf c 5,6,7,8-Tetrahydrofolate

Products

Produced by SBML2LATEX 799 Table 1806: Properties of each product. Id Name SBO M adp c ADP M h c H+ M pi c Phosphate M thfglu c Tetrahydrofolyl-[Glu](2)

Kinetic Law

v944 = not speciﬁed (1888)

6.945 Reaction R THMDP This is an irreversible reaction of two reactants forming three products.

Name thiamin diphosphatase

Reaction equation 2M h2o c + M thmpp c −→ M h c + 2M pi c + M thm c (1889)

Reactants

Table 1807: Properties of each reactant. Id Name SBO M h2o c H2O M thmpp c Thiamine diphosphate

Products

Table 1808: Properties of each product. Id Name SBO M h c H+ M pi c Phosphate M thm c Thiamin

Kinetic Law

v945 = not speciﬁed (1890)

800 Produced by SBML2LATEX 6.946 Reaction R THRD Lr This is a reversible reaction of one reactant forming two products.

Name L-threonine deaminse reversible

Reaction equation M thr DASH L c )−−−−* M 2obut c + M nh4 c (1891)

Reactant

Table 1809: Properties of each reactant. Id Name SBO M thr DASH L c L-Threonine

Products

Table 1810: Properties of each product. Id Name SBO M 2obut c 2-Oxobutanoate M nh4 c Ammonium

Kinetic Law

v946 = not speciﬁed (1892)

6.947 Reaction R THRS This is an irreversible reaction of two reactants forming two products.

Name threonine synthase

Reaction equation M h2o c + M phom c −→ M pi c + M thr DASH L c (1893)

Reactants

Produced by SBML2LATEX 801 Table 1811: Properties of each reactant. Id Name SBO M h2o c H2O M phom c O-Phospho-L-homoserine

Products

Table 1812: Properties of each product. Id Name SBO M pi c Phosphate M thr DASH L c L-Threonine

Kinetic Law

v947 = not speciﬁed (1894)

6.948 Reaction R THRt2r This is a reversible reaction of two reactants forming two products.

Name L-threonine reversible transport via proton symport

Reaction equation M h e + M thr DASH L e )−−−−* M h c + M thr DASH L c (1895)

Reactants

Table 1813: Properties of each reactant. Id Name SBO M h e H+ M thr DASH L e L-Threonine

Products

Table 1814: Properties of each product. Id Name SBO M h c H+

802 Produced by SBML2LATEX Id Name SBO M thr DASH L c L-Threonine

Kinetic Law

v948 = not speciﬁed (1896)

6.949 Reaction R THSFST This is a reversible reaction of two reactants forming three products.

Name Thiosulfate Sulfurtransferase

Reaction equation M cyan c + M tsul c )−−−−* M h c + M so3 c + M tcynt c (1897)

Reactants

Table 1815: Properties of each reactant. Id Name SBO M cyan c Hydrogen cyanide M tsul c Thiosulfate

Products

Table 1816: Properties of each product. Id Name SBO M h c H+ M so3 c Sulﬁte M tcynt c Thiocyanate

Kinetic Law

v949 = not speciﬁed (1898)

6.950 Reaction R THZPSN This is an irreversible reaction of four reactants forming eight products. Name thiazole phosphate synthesis

Produced by SBML2LATEX 803 Reaction equation M atp c + M cys DASH L c + M dxyl5p c + M tyr DASH L c −→ M 4hba c + M 4mpetz c + M ala DASH L c + M amp c + M co2 c + M h2o c + M h c + M ppi c (1899)

Reactants

Table 1817: Properties of each reactant. Id Name SBO M atp c ATP M cys DASH L c L-Cysteine M dxyl5p c 1-deoxy-D-xylulose 5-phosphate M tyr DASH L c L-Tyrosine

Products

Table 1818: Properties of each product. Id Name SBO M 4hba c 4-Hydroxy-benzyl alcohol M 4mpetz c 4-Methyl-5-(2-phosphoethyl)-thiazole M ala DASH L c L-Alanine M amp c AMP M co2 c CO2 M h2o c H2O M h c H+ M ppi c Diphosphate

Kinetic Law

v950 = not speciﬁed (1900)

6.951 Reaction R THZSN This is an irreversible reaction of three reactants forming seven products.

Name thiazole synthesis from xylulose

Reaction equation M cys DASH L c + M dxyl c + M tyr DASH L c −→ M 4hba c + M 4mhetz c + M co2 c + M h2o c + M h c + M nh4 c + M pyr c (1901)

804 Produced by SBML2LATEX Reactants

Table 1819: Properties of each reactant. Id Name SBO M cys DASH L c L-Cysteine M dxyl c 1-deoxy-D-xylulose M tyr DASH L c L-Tyrosine

Products

Table 1820: Properties of each product. Id Name SBO M 4hba c 4-Hydroxy-benzyl alcohol M 4mhetz c 4-Methyl-5-(2-hydroxyethyl)-thiazole M co2 c CO2 M h2o c H2O M h c H+ M nh4 c Ammonium M pyr c Pyruvate

Kinetic Law

v951 = not speciﬁed (1902)

6.952 Reaction R TKT1 This is a reversible reaction of two reactants forming two products.

Name transketolase

Reaction equation M r5p c + M xu5p DASH D c )−−−−* M g3p c + M s7p c (1903)

Reactants

Table 1821: Properties of each reactant. Id Name SBO M r5p c alpha-D-Ribose 5-phosphate M xu5p DASH D c D-Xylulose 5-phosphate

Produced by SBML2LATEX 805 Products

Table 1822: Properties of each product. Id Name SBO M g3p c Glyceraldehyde 3-phosphate M s7p c Sedoheptulose 7-phosphate

Kinetic Law

v952 = not speciﬁed (1904)

6.953 Reaction R TKT2 This is a reversible reaction of two reactants forming two products.

Name transketolase

Reaction equation M e4p c + M xu5p DASH D c )−−−−* M f6p c + M g3p c (1905)

Reactants

Table 1823: Properties of each reactant. Id Name SBO M e4p c D-Erythrose 4-phosphate M xu5p DASH D c D-Xylulose 5-phosphate

Products

Table 1824: Properties of each product. Id Name SBO M f6p c D-Fructose 6-phosphate M g3p c Glyceraldehyde 3-phosphate

Kinetic Law

v953 = not speciﬁed (1906)

806 Produced by SBML2LATEX 6.954 Reaction R TMDK1 This is an irreversible reaction of two reactants forming three products.

Name thymidine kinase (ATP:thymidine)

Reaction equation M atp c + M thymd c −→ M adp c + M dtmp c + M h c (1907)

Reactants

Table 1825: Properties of each reactant. Id Name SBO M atp c ATP M thymd c Thymidine

Products

Table 1826: Properties of each product. Id Name SBO M adp c ADP M dtmp c dTMP M h c H+

Kinetic Law

v954 = not speciﬁed (1908)

6.955 Reaction R TMDPP This is a reversible reaction of two reactants forming two products.

Name thymidine phosphorylase

Reaction equation M pi c + M thymd c )−−−−* M 2dr1p c + M thym c (1909)

Reactants

Produced by SBML2LATEX 807 Table 1827: Properties of each reactant. Id Name SBO M pi c Phosphate M thymd c Thymidine

Products

Table 1828: Properties of each product. Id Name SBO M 2dr1p c 2-Deoxy-D-ribose 1-phosphate M thym c Thymine

Kinetic Law

v955 = not speciﬁed (1910)

6.956 Reaction R TMDS This is an irreversible reaction of two reactants forming two products.

Name thymidylate synthase

Reaction equation M dump c + M mlthf c −→ M dhf c + M dtmp c (1911)

Reactants

Table 1829: Properties of each reactant. Id Name SBO M dump c dUMP M mlthf c 5,10-Methylenetetrahydrofolate

Products

Table 1830: Properties of each product. Id Name SBO M dhf c 7,8-Dihydrofolate

808 Produced by SBML2LATEX Id Name SBO M dtmp c dTMP

Kinetic Law

v956 = not speciﬁed (1912)

6.957 Reaction R TMHAS1 This is an irreversible reaction of three reactants forming two products.

Name trehalose dimycolate synthesis

Reaction equation M tdm1 c + M tdm2 c + M tre c −→ 2M h2o c + M tmha1 c (1913)

Reactants

Table 1831: Properties of each reactant. Id Name SBO M tdm1 c trehalose dimycolate (alpha mycolate + methoxymycolate) M tdm2 c trehalose dimycolate (alpha mycolate + methoxymycolate) M tre c Trehalose

Products

Table 1832: Properties of each product. Id Name SBO M h2o c H2O M tmha1 c tetramycolyl hexaarabinoside (tdm1 + tdm2 +tre) (Mtb)

Kinetic Law

v957 = not speciﬁed (1914)

6.958 Reaction R TMHAS2 This is an irreversible reaction of three reactants forming two products. Name trehalose dimycolate synthesis

Produced by SBML2LATEX 809 Reaction equation M tdm1 c + M tdm3 c + M tre c −→ 2M h2o c + M tmha2 c (1915)

Reactants

Table 1833: Properties of each reactant. Id Name SBO M tdm1 c trehalose dimycolate (alpha mycolate + methoxymycolate) M tdm3 c trehalose dimycolate (alpha mycolate + ketomycolate) M tre c Trehalose

Products

Table 1834: Properties of each product. Id Name SBO M h2o c H2O M tmha2 c tetramycolyl hexaarabinoside (tdm1 + tdm3 + tre) (Mtb)

Kinetic Law

v958 = not speciﬁed (1916)

6.959 Reaction R TMHAS3 This is an irreversible reaction of three reactants forming two products.

Name trehalose dimycolate synthesis

Reaction equation M tdm1 c + M tdm4 c + M tre c −→ 2M h2o c + M tmha3 c (1917)

Reactants

Table 1835: Properties of each reactant. Id Name SBO M tdm1 c trehalose dimycolate (alpha mycolate + methoxymycolate) M tdm4 c trehalose dimycolate (alpha mycolate + methoxymycolate) M tre c Trehalose

810 Produced by SBML2LATEX Products

Table 1836: Properties of each product. Id Name SBO M h2o c H2O M tmha3 c tetramycolyl hexaarabinoside (tdm1 + tdm4 + tre) (Mtb)

Kinetic Law

v959 = not speciﬁed (1918)

6.960 Reaction R TMHAS4 This is an irreversible reaction of three reactants forming two products.

Name trehalose dimycolate synthesis

Reaction equation M tdm2 c + M tdm3 c + M tre c −→ 2M h2o c + M tmha4 c (1919)

Reactants

Table 1837: Properties of each reactant. Id Name SBO M tdm2 c trehalose dimycolate (alpha mycolate + methoxymycolate) M tdm3 c trehalose dimycolate (alpha mycolate + ketomycolate) M tre c Trehalose

Products

Table 1838: Properties of each product. Id Name SBO M h2o c H2O M tmha4 c tetramycolyl hexaarabinoside (tdm2 + tdm3 + tre) (Mtb)

Kinetic Law

v960 = not speciﬁed (1920)

Produced by SBML2LATEX 811 6.961 Reaction R TMHAS5 This is an irreversible reaction of three reactants forming two products.

Name trehalose dimycolate synthesis

Reaction equation M tdm2 c + M tdm4 c + M tre c −→ 2M h2o c + M tmha5 c (1921)

Reactants

Table 1839: Properties of each reactant. Id Name SBO M tdm2 c trehalose dimycolate (alpha mycolate + methoxymycolate) M tdm4 c trehalose dimycolate (alpha mycolate + methoxymycolate) M tre c Trehalose

Products

Table 1840: Properties of each product. Id Name SBO M h2o c H2O M tmha5 c tetramycolyl hexaarabinoside (tdm2 + tdm4 + tre) (Mtb)

Kinetic Law

v961 = not speciﬁed (1922)

6.962 Reaction R TMHAS6 This is an irreversible reaction of three reactants forming two products.

Name trehalose dimycolate synthesis

Reaction equation M tdm3 c + M tdm4 c + M tre c −→ 2M h2o c + M tmha6 c (1923)

Reactants

812 Produced by SBML2LATEX Table 1841: Properties of each reactant. Id Name SBO M tdm3 c trehalose dimycolate (alpha mycolate + ketomycolate) M tdm4 c trehalose dimycolate (alpha mycolate + methoxymycolate) M tre c Trehalose

Products

Table 1842: Properties of each product. Id Name SBO M h2o c H2O M tmha6 c tetramycolyl hexaarabinoside (tdm3 + tdm4 + tre) (Mtb)

Kinetic Law

v962 = not speciﬁed (1924)

6.963 Reaction R TMN This is an irreversible reaction of two reactants forming three products.

Name thiaminase

Reaction equation M h2o c + M thm c −→ M 4ahmmp c + M 4mhetz c + M h c (1925)

Reactants

Table 1843: Properties of each reactant. Id Name SBO M h2o c H2O M thm c Thiamin

Products

Produced by SBML2LATEX 813 Table 1844: Properties of each product. Id Name SBO M 4ahmmp c 4-Amino-5-hydroxymethyl-2-methylpyrimidine M 4mhetz c 4-Methyl-5-(2-hydroxyethyl)-thiazole M h c H+

Kinetic Law

v963 = not speciﬁed (1926)

6.964 Reaction R TMPKr This is a reversible reaction of two reactants forming two products.

Name thiamine-phosphate kinase

Reaction equation M atp c + M thmmp c )−−−−* M adp c + M thmpp c (1927)

Reactants

Table 1845: Properties of each reactant. Id Name SBO M atp c ATP M thmmp c Thiamin monophosphate

Products

Table 1846: Properties of each product. Id Name SBO M adp c ADP M thmpp c Thiamine diphosphate

Kinetic Law

v964 = not speciﬁed (1928)

814 Produced by SBML2LATEX 6.965 Reaction R TMPPP This is an irreversible reaction of three reactants forming two products.

Name thiamine-phosphate diphosphorylase

Reaction equation M 2mahmp c + M 4mpetz c + M h c −→ M ppi c + M thmmp c (1929)

Reactants

Table 1847: Properties of each reactant. Id Name SBO M 2mahmp c 2-Methyl-4-amino-5-hydroxymethylpyrimidine diphosphate M 4mpetz c 4-Methyl-5-(2-phosphoethyl)-thiazole M h c H+

Products

Table 1848: Properties of each product. Id Name SBO M ppi c Diphosphate M thmmp c Thiamin monophosphate

Kinetic Law

v965 = not speciﬁed (1930)

6.966 Reaction R TPI This is a reversible reaction of one reactant forming one product.

Name triose-phosphate isomerase

Reaction equation M dhap c )−−−−* M g3p c (1931)

Reactant

Produced by SBML2LATEX 815 Table 1849: Properties of each reactant. Id Name SBO M dhap c Dihydroxyacetone phosphate

Product

Table 1850: Properties of each product. Id Name SBO M g3p c Glyceraldehyde 3-phosphate

Kinetic Law

v966 = not speciﬁed (1932)

6.967 Reaction R TRDR This is an irreversible reaction of three reactants forming two products.

Name thioredoxin reductase (NADPH)

Reaction equation M h c + M nadph c + M trdox c −→ M nadp c + M trdrd c (1933)

Reactants

Table 1851: Properties of each reactant. Id Name SBO M h c H+ M nadph c Nicotinamide adenine dinucleotide phosphate - reduced M trdox c Oxidized thioredoxin

Products

Table 1852: Properties of each product. Id Name SBO M nadp c Nicotinamide adenine dinucleotide phosphate M trdrd c Reduced thioredoxin

816 Produced by SBML2LATEX Id Name SBO

Kinetic Law

v967 = not speciﬁed (1934)

6.968 Reaction R TRE6PP This is an irreversible reaction of two reactants forming two products.

Name trehalose-phosphatase

Reaction equation M h2o c + M tre6p c −→ M pi c + M tre c (1935)

Reactants

Table 1853: Properties of each reactant. Id Name SBO M h2o c H2O M tre6p c alpha,alpha’-Trehalose 6-phosphate

Products

Table 1854: Properties of each product. Id Name SBO M pi c Phosphate M tre c Trehalose

Kinetic Law

v968 = not speciﬁed (1936)

6.969 Reaction R TRE6PS This is an irreversible reaction of two reactants forming three products.

Name alpha,alpha-trehalose-phosphate synthase (UDP-forming)

Produced by SBML2LATEX 817 Reaction equation M g6p c + M udpg c −→ M h c + M tre6p c + M udp c (1937)

Reactants

Table 1855: Properties of each reactant. Id Name SBO M g6p c D-Glucose 6-phosphate M udpg c UDPglucose

Products

Table 1856: Properties of each product. Id Name SBO M h c H+ M tre6p c alpha,alpha’-Trehalose 6-phosphate M udp c UDP

Kinetic Law

v969 = not speciﬁed (1938)

6.970 Reaction R TRESULT This is an irreversible reaction of two reactants forming three products.

Name trehalose sulfotransferase

Reaction equation M paps c + M tre c −→ M h c + M pap c + M tres c (1939)

Reactants

Table 1857: Properties of each reactant. Id Name SBO M paps c 3’-Phosphoadenylyl sulfate M tre c Trehalose

818 Produced by SBML2LATEX Products

Table 1858: Properties of each product. Id Name SBO M h c H+ M pap c Adenosine 3’,5’-bisphosphate M tres c trehalose 2 sulfate

Kinetic Law

v970 = not speciﬁed (1940)

6.971 Reaction R TREabc This is an irreversible reaction of three reactants forming four products.

Name trehalose transport via ABC system

Reaction equation M atp c + M h2o c + M tre e −→ M adp c + M h c + M pi c + M tre c (1941)

Reactants

Table 1859: Properties of each reactant. Id Name SBO M atp c ATP M h2o c H2O M tre e Trehalose

Products

Table 1860: Properties of each product. Id Name SBO M adp c ADP M h c H+ M pi c Phosphate M tre c Trehalose

Produced by SBML2LATEX 819 Kinetic Law

v971 = not speciﬁed (1942)

6.972 Reaction R TRIATS This is an irreversible reaction of four reactants forming two products.

Name tri-acyl trehalose sulfonation

Reaction equation 3M h c + 2M ocdca c + M tmlgnc c + M tre c −→ 3M h2o c + M triat c (1943)

Reactants

Table 1861: Properties of each reactant. Id Name SBO M h c H+ M ocdca c octadecanoate (n-C18:0) M tmlgnc c tri-methyl lignoceric acid M tre c Trehalose

Products

Table 1862: Properties of each product. Id Name SBO M h2o c H2O M triat c tri-acyl trehalose

Kinetic Law

v972 = not speciﬁed (1944)

6.973 Reaction R TRPS1

This is an irreversible reaction of two reactants forming three products.

Name tryptophan synthase (indoleglycerol phosphate)

820 Produced by SBML2LATEX Reaction equation M 3ig3p c + M ser DASH L c −→ M g3p c + M h2o c + M trp DASH L c (1945)

Reactants

Table 1863: Properties of each reactant. Id Name SBO M 3ig3p c C’-(3-Indolyl)-glycerol 3-phosphate M ser DASH L c L-Serine

Products

Table 1864: Properties of each product. Id Name SBO M g3p c Glyceraldehyde 3-phosphate M h2o c H2O M trp DASH L c L-Tryptophan

Kinetic Law

v973 = not speciﬁed (1946)

6.974 Reaction R TRPS2 This is an irreversible reaction of two reactants forming two products.

Name tryptophan synthase (indole)

Reaction equation M indole c + M ser DASH L c −→ M h2o c + M trp DASH L c (1947)

Reactants

Table 1865: Properties of each reactant. Id Name SBO M indole c Indole M ser DASH L c L-Serine

Produced by SBML2LATEX 821 Products

Table 1866: Properties of each product. Id Name SBO M h2o c H2O M trp DASH L c L-Tryptophan

Kinetic Law

v974 = not speciﬁed (1948)

6.975 Reaction R TRPS3 This is an irreversible reaction of one reactant forming two products.

Name tryptophan synthase (indoleglycerol phosphate)

Reaction equation M 3ig3p c −→ M g3p c + M indole c (1949)

Reactant

Table 1867: Properties of each reactant. Id Name SBO M 3ig3p c C’-(3-Indolyl)-glycerol 3-phosphate

Products

Table 1868: Properties of each product. Id Name SBO M g3p c Glyceraldehyde 3-phosphate M indole c Indole

Kinetic Law

v975 = not speciﬁed (1950)

822 Produced by SBML2LATEX 6.976 Reaction R TRPTA This is a reversible reaction of two reactants forming two products.

Name tryptophan transaminase

Reaction equation M akg c + M trp DASH L c )−−−−* M glu DASH L c + M indpyr c (1951)

Reactants

Table 1869: Properties of each reactant. Id Name SBO M akg c 2-Oxoglutarate M trp DASH L c L-Tryptophan

Products

Table 1870: Properties of each product. Id Name SBO M glu DASH L c L-Glutamate M indpyr c Indolepyruvate

Kinetic Law

v976 = not speciﬁed (1952)

6.977 Reaction R TRPt2r This is a reversible reaction of two reactants forming two products.

Name L-tryptophan reversible transport via proton symport

Reaction equation M h e + M trp DASH L e )−−−−* M h c + M trp DASH L c (1953)

Reactants

Produced by SBML2LATEX 823 Table 1871: Properties of each reactant. Id Name SBO M h e H+ M trp DASH L e L-Tryptophan

Products

Table 1872: Properties of each product. Id Name SBO M h c H+ M trp DASH L c L-Tryptophan

Kinetic Law

v977 = not speciﬁed (1954)

6.978 Reaction R TSULabc This is an irreversible reaction of three reactants forming four products.

Name thiosulfate transport via ABC system

Reaction equation M atp c + M h2o c + M tsul e −→ M adp c + M h c + M pi c + M tsul c (1955)

Reactants

Table 1873: Properties of each reactant. Id Name SBO M atp c ATP M h2o c H2O M tsul e Thiosulfate

Products

824 Produced by SBML2LATEX Table 1874: Properties of each product. Id Name SBO M adp c ADP M h c H+ M pi c Phosphate M tsul c Thiosulfate

Kinetic Law

v978 = not speciﬁed (1956)

6.979 Reaction R TTDCAt2 This is an irreversible reaction of two reactants forming two products.

Name Tetradecanoate transport via proton symport

Reaction equation M h e + M ttdca e −→ M h c + M ttdca c (1957)

Reactants

Table 1875: Properties of each reactant. Id Name SBO M h e H+ M ttdca e tetradecanoate (n-C14:0)

Products

Table 1876: Properties of each product. Id Name SBO M h c H+ M ttdca c tetradecanoate (n-C14:0)

Kinetic Law

v979 = not speciﬁed (1958)

Produced by SBML2LATEX 825 6.980 Reaction R TYRTA This is a reversible reaction of two reactants forming two products.

Name tyrosine transaminase

Reaction equation M akg c + M tyr DASH L c )−−−−* M 34hpp c + M glu DASH L c (1959)

Reactants

Table 1877: Properties of each reactant. Id Name SBO M akg c 2-Oxoglutarate M tyr DASH L c L-Tyrosine

Products

Table 1878: Properties of each product. Id Name SBO M 34hpp c 3-(4-Hydroxyphenyl)pyruvate M glu DASH L c L-Glutamate

Kinetic Law

v980 = not speciﬁed (1960)

6.981 Reaction R TYRt2r This is a reversible reaction of two reactants forming two products.

Name L-tyrosine reversible transport via proton symport

Reaction equation M h e + M tyr DASH L e )−−−−* M h c + M tyr DASH L c (1961)

Reactants

826 Produced by SBML2LATEX Table 1879: Properties of each reactant. Id Name SBO M h e H+ M tyr DASH L e L-Tyrosine

Products

Table 1880: Properties of each product. Id Name SBO M h c H+ M tyr DASH L c L-Tyrosine

Kinetic Law

v981 = not speciﬁed (1962)

6.982 Reaction R UAAGDS This is an irreversible reaction of three reactants forming four products.

Name UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelate synthetase

Reaction equation M 26dap DASH M c + M atp c + M uamag c −→ M adp c + M h c + M pi c + M ugmd c (1963)

Reactants

Table 1881: Properties of each reactant. Id Name SBO M 26dap DASH M c meso-2,6-Diaminoheptanedioate M atp c ATP M uamag c UDP-N-acetylmuramoyl-L-alanyl-D-glutamate

Products

Produced by SBML2LATEX 827 Table 1882: Properties of each product. Id Name SBO M adp c ADP M h c H+ M pi c Phosphate M ugmd c UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminopimelate

Kinetic Law

v982 = not speciﬁed (1964)

6.983 Reaction R UAAGLS1 This is an irreversible reaction of three reactants forming four products.

Name UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-lysine synthetase (alpha-glutamate)

Reaction equation M atp c + M lys DASH L c + M uamag c −→ M adp c + M h c + M pi c + M uAgl c (1965)

Reactants

Table 1883: Properties of each reactant. Id Name SBO M atp c ATP M lys DASH L c L-Lysine M uamag c UDP-N-acetylmuramoyl-L-alanyl-D-glutamate

Products

Table 1884: Properties of each product. Id Name SBO M adp c ADP M h c H+ M pi c Phosphate M uAgl c UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine

828 Produced by SBML2LATEX Kinetic Law

v983 = not speciﬁed (1966)

6.984 Reaction R UAAGLS2 This is an irreversible reaction of three reactants forming four products.

Name UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine synthetase (gamma-glutamate)

Reaction equation M atp c + M lys DASH L c + M uamag c −→ M adp c + M h c + M pi c + M uGgl c (1967)

Reactants

Table 1885: Properties of each reactant. Id Name SBO M atp c ATP M lys DASH L c L-Lysine M uamag c UDP-N-acetylmuramoyl-L-alanyl-D-glutamate

Products

Table 1886: Properties of each product. Id Name SBO M adp c ADP M h c H+ M pi c Phosphate M uGgl c UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysine

Kinetic Law

v984 = not speciﬁed (1968)

6.985 Reaction R UAGCVT This is an irreversible reaction of two reactants forming two products.

Name UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Produced by SBML2LATEX 829 Reaction equation M pep c + M uacgam c −→ M pi c + M uaccg c (1969)

Reactants

Table 1887: Properties of each reactant. Id Name SBO M pep c Phosphoenolpyruvate M uacgam c UDP-N-acetyl-D-glucosamine

Products

Table 1888: Properties of each product. Id Name SBO M pi c Phosphate M uaccg c UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-glucosamine

Kinetic Law

v985 = not speciﬁed (1970)

6.986 Reaction R UAGDP This is an irreversible reaction of three reactants forming two products.

Name UDP-N-acetylglucosamine diphosphorylase

Reaction equation M acgam1p c + M h c + M utp c −→ M ppi c + M uacgam c (1971)

Reactants

Table 1889: Properties of each reactant. Id Name SBO M acgam1p c N-Acetyl-D-glucosamine 1-phosphate M h c H+ M utp c UTP

830 Produced by SBML2LATEX Products

Table 1890: Properties of each product. Id Name SBO M ppi c Diphosphate M uacgam c UDP-N-acetyl-D-glucosamine

Kinetic Law

v986 = not speciﬁed (1972)

6.987 Reaction R UAGPT1 This is an irreversible reaction of two reactants forming three products.

Name UDP-N-acetylglucosamine-N-acetylmuramyl-(pentapeptide)pyrophosphoryl-undecaprenol N-acetylglucosamine transferase

Reaction equation M uaAgla c + M uacgam c −→ M h c + M uaaAgla c + M udp c (1973)

Reactants

Table 1891: Properties of each reactant. Id Name SBO M uaAgla c Undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine M uacgam c UDP-N-acetyl-D-glucosamine

Products

Table 1892: Properties of each product. Id Name SBO M h c H+ M uaaAgla c Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine M udp c UDP

Produced by SBML2LATEX 831 Kinetic Law

v987 = not speciﬁed (1974)

6.988 Reaction R UAGPT2 This is an irreversible reaction of two reactants forming three products.

Name UDP-N-acetylglucosamine-N-acetylmuramyl-(pentapeptide)pyrophosphoryl-undecaprenol N-acetylglucosamine transferase

Reaction equation M uaGgla c + M uacgam c −→ M h c + M uaaGgla c + M udp c (1975)

Reactants

Table 1893: Properties of each reactant. Id Name SBO M uaGgla c Undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine M uacgam c UDP-N-acetyl-D-glucosamine

Products

Table 1894: Properties of each product. Id Name SBO M h c H+ M uaaGgla c Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine M udp c UDP

Kinetic Law

v988 = not speciﬁed (1976)

6.989 Reaction R UAGPT3 This is an irreversible reaction of two reactants forming three products.

Name UDP-N-acetylglucosamine-N-acetylmuramyl-(pentapeptide)pyrophosphoryl-undecaprenol N-acetylglucosamine transferase

832 Produced by SBML2LATEX Reaction equation M uacgam c + M uagmda c −→ M h c + M uaagmda c + M udp c (1977)

Reactants

Table 1895: Properties of each reactant. Id Name SBO M uacgam c UDP-N-acetyl-D-glucosamine M uagmda c Undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

Products

Table 1896: Properties of each product. Id Name SBO M h c H+ M uaagmda c Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-ala-D-glu-meso-2,6-diaminopimeloyl-D-ala-D-ala M udp c UDP

Kinetic Law

v989 = not speciﬁed (1978)

6.990 Reaction R UAMAGS This is an irreversible reaction of three reactants forming four products.

Name UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase

Reaction equation M atp c + M glu DASH D c + M uama c −→ M adp c + M h c + M pi c + M uamag c (1979)

Reactants

Table 1897: Properties of each reactant. Id Name SBO M atp c ATP

Produced by SBML2LATEX 833 Id Name SBO M glu DASH D c D-Glutamate M uama c UDP-N-acetylmuramoyl-L-alanine

Products

Table 1898: Properties of each product. Id Name SBO M adp c ADP M h c H+ M pi c Phosphate M uamag c UDP-N-acetylmuramoyl-L-alanyl-D-glutamate

Kinetic Law

v990 = not speciﬁed (1980)

6.991 Reaction R UAMAS This is an irreversible reaction of three reactants forming four products.

Name UDP-N-acetylmuramoyl-L-alanine synthetase

Reaction equation M ala DASH L c + M atp c + M uamr c −→ M adp c + M h c + M pi c + M uama c (1981)

Reactants

Table 1899: Properties of each reactant. Id Name SBO M ala DASH L c L-Alanine M atp c ATP M uamr c UDP-N-acetylmuramate

Products

834 Produced by SBML2LATEX Table 1900: Properties of each product. Id Name SBO M adp c ADP M h c H+ M pi c Phosphate M uama c UDP-N-acetylmuramoyl-L-alanine

Kinetic Law

v991 = not speciﬁed (1982)

6.992 Reaction R UAMRH This is an irreversible reaction of four reactants forming three products.

Name UDP-MurNAc Hydroxylase

Reaction equation M h c + M nadph c + M o2 c + M uamr c −→ M h2o c + M nadp c + M ugmr c (1983)

Reactants

Table 1901: Properties of each reactant. Id Name SBO M h c H+ M nadph c Nicotinamide adenine dinucleotide phosphate - reduced M o2 c O2 M uamr c UDP-N-acetylmuramate

Products

Table 1902: Properties of each product. Id Name SBO M h2o c H2O M nadp c Nicotinamide adenine dinucleotide phosphate M ugmr c UDP-N-glycolylmuramate

Produced by SBML2LATEX 835 Kinetic Law

v992 = not speciﬁed (1984)

6.993 Reaction R UAPGR This is an irreversible reaction of three reactants forming two products.

Name UDP-N-acetylenolpyruvoylglucosamine reductase

Reaction equation M h c + M nadph c + M uaccg c −→ M nadp c + M uamr c (1985)

Reactants

Table 1903: Properties of each reactant. Id Name SBO M h c H+ M nadph c Nicotinamide adenine dinucleotide phosphate - reduced M uaccg c UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-glucosamine

Products

Table 1904: Properties of each product. Id Name SBO M nadp c Nicotinamide adenine dinucleotide phosphate M uamr c UDP-N-acetylmuramate

Kinetic Law

v993 = not speciﬁed (1986)

6.994 Reaction R UDCPDP This is an irreversible reaction of two reactants forming three products.

Name undecaprenyl-diphosphatase

Reaction equation M h2o c + M udcpdp c −→ M h c + M pi c + M udcpp c (1987)

836 Produced by SBML2LATEX Reactants

Table 1905: Properties of each reactant. Id Name SBO M h2o c H2O M udcpdp c Undecaprenyl diphosphate

Products

Table 1906: Properties of each product. Id Name SBO M h c H+ M pi c Phosphate M udcpp c Undecaprenyl phosphate

Kinetic Law

v994 = not speciﬁed (1988)

6.995 Reaction R UDCPDPS This is an irreversible reaction of two reactants forming two products.

Name Undecaprenyl diphosphate synthase

Reaction equation M frdp c + 8M ipdp c −→ 8M ppi c + M udcpdp c (1989)

Reactants

Table 1907: Properties of each reactant. Id Name SBO M frdp c Farnesyl diphosphate M ipdp c Isopentenyl diphosphate

Products

Produced by SBML2LATEX 837 Table 1908: Properties of each product. Id Name SBO M ppi c Diphosphate M udcpdp c Undecaprenyl diphosphate

Kinetic Law

v995 = not speciﬁed (1990)

6.996 Reaction R UDPDPS This is an irreversible reaction of two reactants forming two products.

Name undecaprenyl-diphosphate synthase

Reaction equation M decdp c + M ipdp c −→ M ppi c + M udcpdp c (1991)

Reactants

Table 1909: Properties of each reactant. Id Name SBO M decdp c all trans Decaprenyl diphosphate M ipdp c Isopentenyl diphosphate

Products

Table 1910: Properties of each product. Id Name SBO M ppi c Diphosphate M udcpdp c Undecaprenyl diphosphate

Kinetic Law

v996 = not speciﬁed (1992)

6.997 Reaction R UDPDPS2 This is an irreversible reaction of two reactants forming two products.

838 Produced by SBML2LATEX Name undecaprenyl-diphosphate synthase

Reaction equation M decdp tb c + M ipdp c −→ M ppi c + M udcpdp c (1993)

Reactants

Table 1911: Properties of each reactant. Id Name SBO M decdp tb c (E,E,E,E,E,E,E,Z,Z) Decaprenyl diphosphate M ipdp c Isopentenyl diphosphate

Products

Table 1912: Properties of each product. Id Name SBO M ppi c Diphosphate M udcpdp c Undecaprenyl diphosphate

Kinetic Law

v997 = not speciﬁed (1994)

6.998 Reaction R UDPG4E This is a reversible reaction of one reactant forming one product.

Name UDPglucose 4-epimerase

Reaction equation M udpg c )−−−−* M udpgal c (1995)

Reactant

Table 1913: Properties of each reactant. Id Name SBO M udpg c UDPglucose

Produced by SBML2LATEX 839 Product

Table 1914: Properties of each product. Id Name SBO M udpgal c UDPgalactose

Kinetic Law

v998 = not speciﬁed (1996)

6.999 Reaction R UDPGALM This is an irreversible reaction of one reactant forming one product.

Name UDPgalactopyranose mutase

Reaction equation M udpgal c −→ M udpgalfur c (1997)

Reactant

Table 1915: Properties of each reactant. Id Name SBO M udpgal c UDPgalactose

Product

Table 1916: Properties of each product. Id Name SBO M udpgalfur c UDP-D-galacto-1,4-furanose

Kinetic Law

v999 = not speciﬁed (1998)

6.1000 Reaction R UDPGD This is an irreversible reaction of three reactants forming three products.

840 Produced by SBML2LATEX Name UDPglucose 6-dehydrogenase

Reaction equation M h2o c + 2M nad c + M udpg c −→ 3M h c + 2M nadh c + M udpglcur c (1999)

Reactants

Table 1917: Properties of each reactant. Id Name SBO M h2o c H2O M nad c Nicotinamide adenine dinucleotide M udpg c UDPglucose

Products

Table 1918: Properties of each product. Id Name SBO M h c H+ M nadh c Nicotinamide adenine dinucleotide - reduced M udpglcur c UDP-D-glucuronate

Kinetic Law

v1000 = not speciﬁed (2000)

6.1001 Reaction R UGAGDS This is an irreversible reaction of three reactants forming four products.

Name UDP-N-glycolylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelate synthetase

Reaction equation M 26dap DASH M c + M atp c + M ugmag c −→ M adp c + M h c + M pi c + M uggmd c (2001)

Reactants

Produced by SBML2LATEX 841 Table 1919: Properties of each reactant. Id Name SBO M 26dap DASH M c meso-2,6-Diaminoheptanedioate M atp c ATP M ugmag c UDP-N-glycolylmuramoyl-L-alanyl-D-glutamate

Products

Table 1920: Properties of each product. Id Name SBO M adp c ADP M h c H+ M pi c Phosphate M uggmd c UDP-N-glycolylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminopimelate

Kinetic Law

v1001 = not speciﬁed (2002)

6.1002 Reaction R UGGPT3 This is an irreversible reaction of two reactants forming three products.

Name UDP-N-glycolylglucosamine-N-acetylmuramyl-(pentapeptide)pyrophosphoryl-undecaprenol N-acetylglucosamine transferase

Reaction equation M uacgam c + M ugggmda c −→ M h c + M udp c + M ugagmda c (2003)

Reactants

Table 1921: Properties of each reactant. Id Name SBO M uacgam c UDP-N-acetyl-D-glucosamine M ugggmda c Undecaprenyl-diphospho-N-glycolylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

Products

842 Produced by SBML2LATEX Table 1922: Properties of each product. Id Name SBO M h c H+ M udp c UDP M ugagmda c Undecaprenyl-diphospho-N-glycolylmuramoyl-(N-acetylglucosamine)-L-ala-D-glu-meso-2,6-diaminopimeloyl-D-ala-D-ala

Kinetic Law

v1002 = not speciﬁed (2004)

6.1003 Reaction R UGLDDS1 This is an irreversible reaction of three reactants forming three products.

Name UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine synthetase (alpha- glutamate)

Reaction equation M alaala c + M atp c + M uAgl c −→ M adp c + M pi c + M uAgla c (2005)

Reactants

Table 1923: Properties of each reactant. Id Name SBO M alaala c D-Alanyl-D-alanine M atp c ATP M uAgl c UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine

Products

Table 1924: Properties of each product. Id Name SBO M adp c ADP M pi c Phosphate M uAgla c UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine

Produced by SBML2LATEX 843 Kinetic Law

v1003 = not speciﬁed (2006)

6.1004 Reaction R UGLDDS2 This is an irreversible reaction of three reactants forming three products.

Name UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine synthetase (gamma- glutamate)

Reaction equation M alaala c + M atp c + M uGgl c −→ M adp c + M pi c + M uGgla c (2007)

Reactants

Table 1925: Properties of each reactant. Id Name SBO M alaala c D-Alanyl-D-alanine M atp c ATP M uGgl c UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysine

Products

Table 1926: Properties of each product. Id Name SBO M adp c ADP M pi c Phosphate M uGgla c UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine

Kinetic Law

v1004 = not speciﬁed (2008)

6.1005 Reaction R UGMAGS This is an irreversible reaction of three reactants forming four products.

Name UDP-N-glycolylmuramoyl-L-alanyl-D-glutamate synthetase

844 Produced by SBML2LATEX Reaction equation M atp c + M glu DASH D c + M ugma c −→ M adp c + M h c + M pi c + M ugmag c (2009)

Reactants

Table 1927: Properties of each reactant. Id Name SBO M atp c ATP M glu DASH D c D-Glutamate M ugma c UDP-N-glycolylmuramoyl-L-alanine

Products

Table 1928: Properties of each product. Id Name SBO M adp c ADP M h c H+ M pi c Phosphate M ugmag c UDP-N-glycolylmuramoyl-L-alanyl-D-glutamate

Kinetic Law

v1005 = not speciﬁed (2010)

6.1006 Reaction R UGMAS This is an irreversible reaction of three reactants forming four products.

Name UDP-N-glycolylmuramoyl-L-alanine synthetase

Reaction equation M ala DASH L c + M atp c + M ugmr c −→ M adp c + M h c + M pi c + M ugma c (2011)

Reactants

Produced by SBML2LATEX 845 Table 1929: Properties of each reactant. Id Name SBO M ala DASH L c L-Alanine M atp c ATP M ugmr c UDP-N-glycolylmuramate

Products

Table 1930: Properties of each product. Id Name SBO M adp c ADP M h c H+ M pi c Phosphate M ugma c UDP-N-glycolylmuramoyl-L-alanine

Kinetic Law

v1006 = not speciﬁed (2012)

6.1007 Reaction R UGMDDS This is an irreversible reaction of three reactants forming four products.

Name UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine synthetase

Reaction equation M alaala c + M atp c + M ugmd c −→ M adp c + M h c + M pi c + M ugmda c (2013)

Reactants

Table 1931: Properties of each reactant. Id Name SBO M alaala c D-Alanyl-D-alanine M atp c ATP M ugmd c UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminopimelate

846 Produced by SBML2LATEX Products

Table 1932: Properties of each product. Id Name SBO M adp c ADP M h c H+ M pi c Phosphate M ugmda c UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

Kinetic Law

v1007 = not speciﬁed (2014)

6.1008 Reaction R UGMDDS2 This is an irreversible reaction of three reactants forming four products.

Name UDP-N-glycolylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D- alanine synthetase

Reaction equation M alaala c + M atp c + M uggmd c −→ M adp c + M h c + M pi c + M uggmda c (2015)

Reactants

Table 1933: Properties of each reactant. Id Name SBO M alaala c D-Alanyl-D-alanine M atp c ATP M uggmd c UDP-N-glycolylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminopimelate

Products

Table 1934: Properties of each product. Id Name SBO M adp c ADP M h c H+ M pi c Phosphate

Produced by SBML2LATEX 847 Id Name SBO M uggmda c UDP-N-glycolylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

Kinetic Law

v1008 = not speciﬁed (2016)

6.1009 Reaction R UMPK This is a reversible reaction of two reactants forming two products.

Name UMP kinase

Reaction equation M atp c + M ump c )−−−−* M adp c + M udp c (2017)

Reactants

Table 1935: Properties of each reactant. Id Name SBO M atp c ATP M ump c UMP

Products

Table 1936: Properties of each product. Id Name SBO M adp c ADP M udp c UDP

Kinetic Law

v1009 = not speciﬁed (2018)

6.1010 Reaction R UPP3MT This is an irreversible reaction of two reactants forming three products.

Name uroporphyrinogen methyltransferase

848 Produced by SBML2LATEX Reaction equation 2M amet c + M uppg3 c −→ 2M ahcys c + M dscl c + M h c (2019)

Reactants

Table 1937: Properties of each reactant. Id Name SBO M amet c S-Adenosyl-L-methionine M uppg3 c Uroporphyrinogen III

Products

Table 1938: Properties of each product. Id Name SBO M ahcys c S-Adenosyl-L-homocysteine M dscl c dihydrosirohydrochlorin M h c H+

Kinetic Law

v1010 = not speciﬁed (2020)

6.1011 Reaction R UPP3S This is an irreversible reaction of one reactant forming two products.

Name uroporphyrinogen-III synthase

Reaction equation M hmbil c −→ M h2o c + M uppg3 c (2021)

Reactant

Table 1939: Properties of each reactant. Id Name SBO M hmbil c Hydroxymethylbilane

Produced by SBML2LATEX 849 Products

Table 1940: Properties of each product. Id Name SBO M h2o c H2O M uppg3 c Uroporphyrinogen III

Kinetic Law

v1011 = not speciﬁed (2022)

6.1012 Reaction R UPPDC1 This is an irreversible reaction of two reactants forming two products.

Name uroporphyrinogen decarboxylase (uroporphyrinogen III)

Reaction equation 4M h c + M uppg3 c −→ 4M co2 c + M cpppg3 c (2023)

Reactants

Table 1941: Properties of each reactant. Id Name SBO M h c H+ M uppg3 c Uroporphyrinogen III

Products

Table 1942: Properties of each product. Id Name SBO M co2 c CO2 M cpppg3 c Coproporphyrinogen III

Kinetic Law

v1012 = not speciﬁed (2024)

850 Produced by SBML2LATEX 6.1013 Reaction R UPPDC2 This is an irreversible reaction of two reactants forming two products.

Name uroporphyrinogen decarboxylase (uroporphyrinogen I)

Reaction equation 4M h c + M uppg1 c −→ 4M co2 c + M cpppg1 c (2025)

Reactants

Table 1943: Properties of each reactant. Id Name SBO M h c H+ M uppg1 c Uroporphyrinogen I

Products

Table 1944: Properties of each product. Id Name SBO M co2 c CO2 M cpppg1 c Coproporphyrinogen I

Kinetic Law

v1013 = not speciﬁed (2026)

6.1014 Reaction R UPPRT This is an irreversible reaction of two reactants forming two products.

Name uracil phosphoribosyltransferase

Reaction equation M prpp c + M ura c −→ M ppi c + M ump c (2027)

Reactants

Produced by SBML2LATEX 851 Table 1945: Properties of each reactant. Id Name SBO M prpp c 5-Phospho-alpha-D-ribose 1-diphosphate M ura c Uracil

Products

Table 1946: Properties of each product. Id Name SBO M ppi c Diphosphate M ump c UMP

Kinetic Law

v1014 = not speciﬁed (2028)

6.1015 Reaction R UREA This is an irreversible reaction of three reactants forming two products.

Name urease

Reaction equation M h2o c + 2M h c + M urea c −→ M co2 c + 2M nh4 c (2029)

Reactants

Table 1947: Properties of each reactant. Id Name SBO M h2o c H2O M h c H+ M urea c Urea

Products

852 Produced by SBML2LATEX Table 1948: Properties of each product. Id Name SBO M co2 c CO2 M nh4 c Ammonium

Kinetic Law

v1015 = not speciﬁed (2030)

6.1016 Reaction R URIDK1 This is an irreversible reaction of two reactants forming two products.

Name uridylate kinase (UMP)

Reaction equation M atp c + M ump c −→ M adp c + M udp c (2031)

Reactants

Table 1949: Properties of each reactant. Id Name SBO M atp c ATP M ump c UMP

Products

Table 1950: Properties of each product. Id Name SBO M adp c ADP M udp c UDP

Kinetic Law

v1016 = not speciﬁed (2032)

6.1017 Reaction R URIDK2r This is a reversible reaction of two reactants forming two products.

Produced by SBML2LATEX 853 Name uridylate kinase (dUMP)

Reaction equation M atp c + M dump c )−−−−* M adp c + M dudp c (2033)

Reactants

Table 1951: Properties of each reactant. Id Name SBO M atp c ATP M dump c dUMP

Products

Table 1952: Properties of each product. Id Name SBO M adp c ADP M dudp c dUDP

Kinetic Law

v1017 = not speciﬁed (2034)

6.1018 Reaction R URIK2 This is an irreversible reaction of two reactants forming three products.

Name uridine kinase (GTP:Uridine)

Reaction equation M gtp c + M uri c −→ M gdp c + M h c + M ump c (2035)

Reactants

Table 1953: Properties of each reactant. Id Name SBO M gtp c GTP M uri c Uridine

854 Produced by SBML2LATEX Products

Table 1954: Properties of each product. Id Name SBO M gdp c GDP M h c H+ M ump c UMP

Kinetic Law

v1018 = not speciﬁed (2036)

6.1019 Reaction R VALTA This is a reversible reaction of two reactants forming two products.

Name valine transaminase

Reaction equation M akg c + M val DASH L c )−−−−* M 3mob c + M glu DASH L c (2037)

Reactants

Table 1955: Properties of each reactant. Id Name SBO M akg c 2-Oxoglutarate M val DASH L c L-Valine

Products

Table 1956: Properties of each product. Id Name SBO M 3mob c 3-Methyl-2-oxobutanoate M glu DASH L c L-Glutamate

Kinetic Law

v1019 = not speciﬁed (2038)

Produced by SBML2LATEX 855 6.1020 Reaction R VALt2r This is a reversible reaction of two reactants forming two products.

Name L-valine reversible transport via proton symport

Reaction equation M h e + M val DASH L e )−−−−* M h c + M val DASH L c (2039)

Reactants

Table 1957: Properties of each reactant. Id Name SBO M h e H+ M val DASH L e L-Valine

Products

Table 1958: Properties of each product. Id Name SBO M h c H+ M val DASH L c L-Valine

Kinetic Law

v1020 = not speciﬁed (2040)

6.1021 Reaction R XPPT This is an irreversible reaction of two reactants forming two products.

Name xanthine phosphoribosyltransferase

Reaction equation M prpp c + M xan c −→ M ppi c + M xmp c (2041)

Reactants

856 Produced by SBML2LATEX Table 1959: Properties of each reactant. Id Name SBO M prpp c 5-Phospho-alpha-D-ribose 1-diphosphate M xan c Xanthine

Products

Table 1960: Properties of each product. Id Name SBO M ppi c Diphosphate M xmp c Xanthosine 5’-phosphate

Kinetic Law

v1021 = not speciﬁed (2042)

6.1022 Reaction R XYLK This is an irreversible reaction of two reactants forming three products.

Name xylulokinase

Reaction equation M atp c + M xylu DASH D c −→ M adp c + M h c + M xu5p DASH D c (2043)

Reactants

Table 1961: Properties of each reactant. Id Name SBO M atp c ATP M xylu DASH D c D-Xylulose

Products

Table 1962: Properties of each product. Id Name SBO M adp c ADP

Produced by SBML2LATEX 857 Id Name SBO M h c H+ M xu5p DASH D c D-Xylulose 5-phosphate

Kinetic Law

v1022 = not speciﬁed (2044)

6.1023 Reaction R XYLabc This is an irreversible reaction of three reactants forming four products.

Name D-xylose transport via ABC system

Reaction equation M atp c + M h2o c + M xyl DASH D e −→ M adp c + M h c + M pi c + M xyl DASH D c (2045)

Reactants

Table 1963: Properties of each reactant. Id Name SBO M atp c ATP M h2o c H2O M xyl DASH D e D-Xylose

Products

Table 1964: Properties of each product. Id Name SBO M adp c ADP M h c H+ M pi c Phosphate M xyl DASH D c D-Xylose

Kinetic Law

v1023 = not speciﬁed (2046)

858 Produced by SBML2LATEX 6.1024 Reaction R YUMPS This is a reversible reaction of two reactants forming two products.

Name yUMP synthetase

Reaction equation M r5p c + M ura c )−−−−* M h2o c + M psd5p c (2047)

Reactants

Table 1965: Properties of each reactant. Id Name SBO M r5p c alpha-D-Ribose 5-phosphate M ura c Uracil

Products

Table 1966: Properties of each product. Id Name SBO M h2o c H2O M psd5p c Pseudouridine 5’-phosphate

Kinetic Law

v1024 = not speciﬁed (2048)

6.1025 Reaction R biomass Mtb 9 60atp This is an irreversible reaction of 92 reactants forming three products.

Name biomass composition for Mycobacterium tuberculosis (v 0.1) - 60 atp

Reaction equation 0·001681M Ac1PIM1 c + 0·001488M Ac1PIM2 c + 0·001335M Ac1PIM3 c + 0·001211M Ac1PIM4 c + 0·001274M Ac2PIM2 c + 0·002076M PIM1 c + 0·00179M PIM2 c + 0·001573M PIM3 c + 0·001403M PIM4 c + 0·001266M PIM5 c + 0·001154M PIM6 c + 0·230181M acgam1p c + 0·405957M ala DASH L c + 0·139026M amp c + 7.31 · 10−4M arabinanagalfragund c + 0·015676M arach c + 0·120416M arg DASH L c + 0·047699M asn DASH L c + 0·120308M asp DASH L c + 60M atp c + 0·005859M clpn160190 c + 0·250951M cmp c + 0·022M cys DASH L c + 0·003492M damp c + 0·006663M dcmp c + 0·006659M dgmp c + 0·003653M dtmp c + 0·001498M fcmcbtt c + 0·055474M gal c + 0·163152M glc DASH D c + 0·05812M gln DASH L c + 0·090007M glu DASH L c + 0·335808M gly c + 0·025359M glyc c + 0·243651M gmp c + 60M h2o c + 0·235152M hdca c + 0·01094M hdcea c + 0·058352M hexc c + 0·040617M his DASH L c + 0·087731M ile DASH L c + 0·003338M kmycolate c + 0·204706M leu DASH L c + 0·03909M lys DASH L c + 0·095065M man c + 0·00784M mbhn c + 0·001402M mcbts c + 0·034889M met DASH L c + 0·001184M mfrrppdima c + 0·003291M mkmycolate c + 0·003365M mmmycolate c + 0·095802M mocdca c + 0·011003M mycolate c + 0·034837M ocdca c + 0·009849M ocdcea c + 0·006798M pa160190 c + 0·00724M pa160 c + 0·006407M pa190190 c + 0·001251M pat c + 2.73 · 10−4M pdima c + 0·004061M pe160 c + 0·01885M peptido TB1 c + 0·01885M peptido TB2 c + 0·00613M pg160190 c + 0·006487M pg160 c + 0·00581M pg190 c + 0·006453M phdca c + 0·048102M phe DASH L c + 2.63 · 10−4M ppdima c + 0·138034M pro DASH L c + 0·021723M rib DASH D c + 0·143397M ser DASH L c + 0·001137M sl1 c + 0·001176M tat c + 0·135712M thr DASH L c + 0·001106M tmha1 c + 0·0011M tmha2 c + 0·001104M tmha3 c + 0·001097M tmha4 c + 0·006491M tre6p c + 0·00797M tre c + 0·006474M tres c + 0·020124M trp DASH L c + 0·012193M ttdca c + 0·031756M tyr DASH L c + 0·001008M uaaAgla c + 0·001008M uaaGgla c + 9.86 · 10−4M uaagmda c + 0·002793M uamr c + 9.77 · 10−4M ugagmda c + 0·131604M ump c + 0·205827M val DASH L c −→ 60M adp c + 60M h c + 60M pi c (2049)

Reactants

Produced by SBML2LATEX 859 Table 1967: Properties of each reactant. Id Name SBO M Ac1PIM1 c acyl phosphatidylinositol mannoside (tuberculosis) M Ac1PIM2 c acyl phosphatidylinositol mannoside di-mannose (tuberculosis) M Ac1PIM3 c acyl phosphatidylinositol mannoside tri-mannose (tuberculosis) M Ac1PIM4 c acyl phosphatidylinositol mannoside tetra-mannose (tuberculosis) M Ac2PIM2 c di-acyl phosphatidylinositol mannoside di-mannose (tuberculosis) M PIM1 c phosphatidylinositol mannoside (tuberculosis) M PIM2 c phosphatidylinositol mannoside di-mannose (tuberculosis) M PIM3 c phosphatidylinositol mannoside tri-mannose (tuberculosis) M PIM4 c phosphatidylinositol mannoside tetra-mannose (tuberculosis) M PIM5 c phosphatidylinositol mannoside penta-mannose (tuberculosis) M PIM6 c phosphatidylinositol mannoside hexa-mannose (tuberculosis) M acgam1p c N-Acetyl-D-glucosamine 1-phosphate M ala DASH L c L-Alanine M amp c AMP M arabinanagalfragund c arabinan-arabinofuranose-galactofuranosyl(30)-rhamanosyl-N-acetylglucosamyl-undecaprenyl diphosphate (M tb) M arach c Arachidic acid M arg DASH L c L-Arginine M asn DASH L c L-Asparagine M asp DASH L c L-Aspartate M atp c ATP M clpn160190 c cardiolipin (dihexadecanoyl, dimethylstearoyl) M cmp c CMP M cys DASH L c L-Cysteine M damp c dAMP M dcmp c dCMP M dgmp c dGMP M dtmp c dTMP M fcmcbtt c iron(III) chelated carboxymycobactin T (R=8 carbon, ﬁnal carbon is carboxyl group) M gal c D-Galactose M glc DASH D c D-Glucose M gln DASH L c L-Glutamine M glu DASH L c L-Glutamate M gly c Glycine M glyc c Glycerol M gmp c GMP M h2o c H2O M hdca c Hexadecanoate (n-C16:0) M hdcea c Hexadecenoate (n-C16:1) M hexc c hexacosanoate (n-C26:0) M his DASH L c L-Histidine

860 Produced by SBML2LATEX Id Name SBO M ile DASH L c L-Isoleucine M kmycolate c keto mycolate (2 cyclopropanated rings) M leu DASH L c L-Leucine M lys DASH L c L-Lysine M man c D-Mannose M mbhn c methyl behenic acid M mcbts c mycobactin S M met DASH L c L-Methionine M mfrrppdima c phenolic glycolipid (Mtb) M mkmycolate c keto mycolate (1 cyclopropanated rings) M mmmycolate c methoxy mycolate (1 cyclopropanated ring) M mocdca c 10-methylstearic acid M mycolate c mycolate (2 cyclopropanated rings) M ocdca c octadecanoate (n-C18:0) M ocdcea c octadecenoate (n-C18:1) M pa160190 c 1,2-sn-glycerol 3-phosphate M pa160 c 1,2-dihexadecanoyl-sn-glycerol 3-phosphate M pa190190 c 1,2-sn-glycerol 3-phosphate M pat c penta-acyl trehalose M pdima c phthiocerol dimycocerosate A (Mtb) M pe160 c phosphatidylethanolamine (dihexadecanoyl, n-C16:0) M peptido TB1 c peptidoglycan subunit (for Mycobacterium tuberculosis) M peptido TB2 c peptidoglycan subunit (for Mycobacterium tuberculosis) M pg160190 c Phosphatidylglycerol (hexadecanoyl, methylstearoyl) M pg160 c Phosphatidylglycerol (dihexadecanoyl, n-C16:0) M pg190 c Phosphatidylglycerol (dimethylstearoyl, C19:0) M phdca c phenol palmitic acid M phe DASH L c L-Phenylalanine M ppdima c phenol phthiocerol dimycocerosate (Mtb) M pro DASH L c L-Proline M rib DASH D c D-Ribose M ser DASH L c L-Serine M sl1 c sulfonated tetra-acyl trehalose M tat c tetra-acyl trehalose M thr DASH L c L-Threonine M tmha1 c tetramycolyl hexaarabinoside (tdm1 + tdm2 +tre) (Mtb) M tmha2 c tetramycolyl hexaarabinoside (tdm1 + tdm3 + tre) (Mtb) M tmha3 c tetramycolyl hexaarabinoside (tdm1 + tdm4 + tre) (Mtb) M tmha4 c tetramycolyl hexaarabinoside (tdm2 + tdm3 + tre) (Mtb) M tre6p c alpha,alpha’-Trehalose 6-phosphate M tre c Trehalose M tres c trehalose 2 sulfate

Produced by SBML2LATEX 861 Id Name SBO M trp DASH L c L-Tryptophan M ttdca c tetradecanoate (n-C14:0) M tyr DASH L c L-Tyrosine M uaaAgla c Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine M uaaGgla c Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine M uaagmda c Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-ala-D-glu-meso-2,6-diaminopimeloyl-D-ala-D-ala M uamr c UDP-N-acetylmuramate M ugagmda c Undecaprenyl-diphospho-N-glycolylmuramoyl-(N-acetylglucosamine)-L-ala-D-glu-meso-2,6-diaminopimeloyl-D-ala-D-ala M ump c UMP M val DASH L c L-Valine

Products

Table 1968: Properties of each product. Id Name SBO M adp c ADP M h c H+ M pi c Phosphate

Kinetic Law

v1025 = not speciﬁed (2050)

7 Derived Rate Equations

When interpreted as an ordinary differential equation framework, this model implies the following set of equations for the rates of change of each species. The identiﬁers for reactions, which are not deﬁned properly or which are lacking a kinetic equation, are highlighted in red.

7.1 Species M 10fthf c Name 10-Formyltetrahydrofolate

Charge -2

This species takes part in six reactions (as a reactant in R AICART, R FMETTRS, R FTHFD, R- GARFT and as a product in R FTHFL, R MTHFC). d M 10fthf c = v + v − v − v − v − v (2051) dt 427 635 64 411 426 455

862 Produced by SBML2LATEX 7.2 Species M 12dgr160 c

Name 1,2-Diacyl-sn-glycerol (dihexadecanoyl, n-C16:0)

Charge 0

This species takes part in three reactions (as a reactant in R DAGK160 and as a product in R- PAPA160, R PLCD).

d M 12dgr160 c = v + v − v (2052) dt 742 801 192

7.3 Species M 13dpg c

Name 3-Phospho-D-glyceroyl phosphate

Charge -4

This species takes part in two reactions (as a product in R GAPD, R PGK).

d M 13dpg c = v + v (2053) dt 454 773

7.4 Species M 1hdecg3p c

Name 1-hexadecanoyl-sn-glycerol 3-phosphate

Charge -2

This species takes part in three reactions (as a reactant in R AGPAT160, R AGPAT160190 and as a product in R G3PAT160).

d M 1hdecg3p c = v − v − v (2054) dt 442 57 58

7.5 Species M 1msg3p c

Name 1-Acyl-sn-glycerol 3-phosphate (branched C19:0)

Charge -2

This species takes part in two reactions (as a reactant in R AGPAT190 and as a product in R- G3PAT190).

d M 1msg3p c = v − v (2055) dt 443 59

Produced by SBML2LATEX 863 7.6 Species M 1pyr5c c Name 1-Pyrroline-5-carboxylate

Charge -1 This species takes part in ﬁve reactions (as a reactant in R P5CD, R P5CR, R P5CRx and as a product in R G5SADs, R PROD2). d M 1pyr5c c = v + v − v − v − v (2056) dt 445 844 737 738 739

7.7 Species M 23dhba c Name (2,3-Dihydroxybenzoyl)adenylate

Charge -1 This species takes part in one reaction (as a reactant in R ENTCS). d M 23dhba c = −3v (2057) dt 255

7.8 Species M 23dhdp c Name 2,3-Dihydrodipicolinate

Charge -2 This species takes part in two reactions (as a reactant in R DHDPRy and as a product in R DHDPS). d M 23dhdp c = v − v (2058) dt 220 219

7.9 Species M 23dhmb c Name (R)-2,3-Dihydroxy-3-methylbutanoate

Charge -1 This species takes part in two reactions (as a reactant in R DHAD1 and as a product in R KARA1i). d M 23dhmb c = v − v (2059) dt 564 217

7.10 Species M 23dhmp c Name (R)-2,3-Dihydroxy-3-methylpentanoate

Charge -1 This species takes part in two reactions (as a reactant in R DHAD2 and as a product in R KARA2i). d M 23dhmp c = v − v (2060) dt 565 218

864 Produced by SBML2LATEX 7.11 Species M 25aics c

Name (S)-2-[5-Amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido]succinate

Charge -4

This species takes part in two reactions (as a reactant in R ADSL2r and as a product in R PRASCS).

d M 25aics c = v − v (2061) dt 834 51

7.12 Species M 25dhpp c

Name 2,5-Diamino-6-hydroxy-4-(5’-phosphoribosylamino)-pyrimidine

Charge -2

This species takes part in two reactions (as a reactant in R DHPPDA and as a product in R GTPCII).

d M 25dhpp c = v − v (2062) dt 507 231

7.13 Species M 25drapp c

Name 2,5-Diamino-6-(ribosylamino)-4-(3H)-pyrimidinone 5’-phosphate

Charge -2

This species takes part in two reactions (as a reactant in R DHPPDA2 and as a product in R- GTPCII2).

d M 25drapp c = v − v (2063) dt 508 232

7.14 Species M 26dap DASH LL c

Name LL-2,6-Diaminoheptanedioate

Charge 0

This species takes part in two reactions (as a reactant in R DAPE and as a product in R SDPDS).

d M 26dap DASH LL c = v − v (2064) dt 896 196

Produced by SBML2LATEX 865 7.15 Species M 26dap DASH M c

Name meso-2,6-Diaminoheptanedioate

Charge 0

This species takes part in four reactions (as a reactant in R DAPDC, R UAAGDS, R UGAGDS and as a product in R DAPE).

d M 26dap DASH M c = v − v − v − v (2065) dt 196 195 982 1001

7.16 Species M 2agpe160 c

Name 2-Acyl-sn-glycero-3-phosphoethanolamine (n-C16:0)

Charge 0

This species takes part in three reactions (as a reactant in R 2AGPEAT160, R LPLIPAL2E160 and as a product in R PLIPA1E160).

d M 2agpe160 c = v − v − v (2066) dt 802 1 574

7.17 Species M 2agpe180 c

Name 2-Acyl-sn-glycero-3-phosphoethanolamine (n-C18:0)

Charge 0

This species takes part in three reactions (as a reactant in R 2AGPEAT180, R LPLIPAL2E180 and as a product in R PLIPA1E180).

d M 2agpe180 c = v − v − v (2067) dt 803 2 575

7.18 Species M 2ahbut c

Name (S)-2-Aceto-2-hydroxybutanoate

Charge -1

This species takes part in two reactions (as a reactant in R KARA2i and as a product in R ACHBS).

d M 2ahbut c = v − v (2068) dt 20 565

866 Produced by SBML2LATEX 7.19 Species M 2ahhmd c Name 2-Amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate

Charge -3 This species takes part in two reactions (as a reactant in R FOLD3 and as a product in R HPPK). d M 2ahhmd c = v − v (2069) dt 533 413

7.20 Species M 2ahhmp c Name 2-Amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine

Charge 0 This species takes part in two reactions (as a reactant in R HPPK and as a product in R DHNPA). d M 2ahhmp c = v − v (2070) dt 225 533

7.21 Species M 2c25dho c Name 2-Carboxy-2,5-dihydro-5-oxofuran-2-acetate

Charge 0 This species takes part in one reaction (as a reactant in R CMLDC). d M 2c25dho c = −v (2071) dt 152

7.22 Species M 2cpr5p c Name 1-(2-Carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate

Charge -3 This species takes part in two reactions (as a reactant in R IGPS and as a product in R PRAIi). d M 2cpr5p c = v − v (2072) dt 832 550

7.23 Species M 2dda7p c Name 2-Dehydro-3-deoxy-D-arabino-heptonate 7-phosphate

Charge -3 This species takes part in two reactions (as a reactant in R DHQS and as a product in R DDPA). d M 2dda7p c = v − v (2073) dt 212 235

Produced by SBML2LATEX 867 7.24 Species M 2dglcn c

Name 2-Deoxy-D-gluconate

Charge -1

This species takes part in one reaction (as a reactant in R DGC3D).

d M 2dglcn c = −v (2074) dt 215

7.25 Species M 2dhp c

Name 2-Dehydropantoate

Charge -1

This species takes part in two reactions (as a reactant in R DPR and as a product in R MOHMT).

d M 2dhp c = v − v (2075) dt 627 243

7.26 Species M 2dmmq6 c

Name 2-Demethylmenaquinone 6

Charge 0

This species takes part in two reactions (as a reactant in R AMMQT6 and as a product in R- DHNAOT2).

d M 2dmmq6 c = v − v (2076) dt 224 82

7.27 Species M 2dmmq8 c

Name 2-Demethylmenaquinone 8

Charge 0

This species takes part in six reactions (as a reactant in R AMMQT8, R AMMQT8 2, R GLYCTO4, R NADH9 and as a product in R DHNAOT, R FRD3).

d M 2dmmq8 c = v + v − v − v − v − v (2077) dt 223 419 83 84 490 668

868 Produced by SBML2LATEX 7.28 Species M 2dmmql8 c

Name 2-Demethylmenaquinol 8

Charge 0

This species takes part in three reactions (as a reactant in R FRD3 and as a product in R GLYCTO4, R NADH9).

d M 2dmmql8 c = v + v − v (2078) dt 490 668 419

7.29 Species M 2dr1p c

Name 2-Deoxy-D-ribose 1-phosphate

Charge -2

This species takes part in ﬁve reactions (as a product in R DURIPP, R PUNP2, R PUNP4, R PUNP6, R TMDPP).

d M 2dr1p c = v + v + v + v + v (2079) dt 248 858 860 862 955

7.30 Species M 2dr5p c

Name 2-Deoxy-D-ribose 5-phosphate

Charge -2

This species takes part in one reaction (as a reactant in R DRPA).

d M 2dr5p c = −v (2080) dt 244

7.31 Species M 2ippm c

Name 2-Isopropylmaleate

Charge -2

This species takes part in two reactions (as a reactant in R IPPMIb and as a product in R IPPMIa).

d M 2ippm c = v − v (2081) dt 561 562

Produced by SBML2LATEX 869 7.32 Species M 2mahmp c

Name 2-Methyl-4-amino-5-hydroxymethylpyrimidine diphosphate

Charge -3

This species takes part in two reactions (as a reactant in R TMPPP and as a product in R PMPK).

d M 2mahmp c = v − v (2082) dt 806 965

7.33 Species M 2me4p c

Name 2-C-methyl-D-erythritol 4-phosphate

Charge -2

This species takes part in two reactions (as a reactant in R MEPCT and as a product in R DXPRIi).

d M 2me4p c = v − v (2083) dt 250 604

7.34 Species M 2mecdp c

Name 2-C-methyl-D-erythritol 2,4-cyclodiphosphate

Charge -2

This species takes part in two reactions (as a reactant in R MECDPDH and as a product in R- MECDPS).

d M 2mecdp c = v − v (2084) dt 602 601

7.35 Species M 2mop c

Name 2-Methyl-3-oxopropanoate

Charge -1

This species takes part in one reaction (as a reactant in R MMSAD1).

d M 2mop c = −v (2085) dt 621

870 Produced by SBML2LATEX 7.36 Species M 2obut c

Name 2-Oxobutanoate

Charge -1

This species takes part in four reactions (as a reactant in R ACHBS and as a product in R CYSTGL, R SHSL4r, R THRD Lr).

d M 2obut c = v + v + v − v (2086) dt 177 915 946 20

7.37 Species M 2p4c2me c

Name 2-phospho-4-(cytidine 5’-diphospho)-2-C-methyl-D-erythritol

Charge -4

This species takes part in two reactions (as a reactant in R MECDPS and as a product in R CDPMEK).

d M 2p4c2me c = v − v (2087) dt 137 602

7.38 Species M 2pg c

Name D-Glycerate 2-phosphate

Charge -3

This species takes part in two reactions (as a reactant in R ENO, R PGM).

d M 2pg c = −v − v (2088) dt 254 777

7.39 Species M 2pglyc c

Name 2-Phosphoglycolate

Charge -3

This species takes part in one reaction (as a reactant in R PGLYCP).

d M 2pglyc c = −v (2089) dt 776

Produced by SBML2LATEX 871 7.40 Species M 2shchc c Name 2-Succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate

Charge -2 This species takes part in three reactions (as a reactant in R SUCBZS and as a product in R- SHCHCS, R SHCHCS2). d M 2shchc c = v + v − v (2090) dt 905 906 923

7.41 Species M 34hpp c Name 3-(4-Hydroxyphenyl)pyruvate

Charge -1 This species takes part in two reactions (as a product in R PPND, R TYRTA). d M 34hpp c = v + v (2091) dt 824 980

7.42 Species M 35cgmp c Name 3’,5’-Cyclic GMP

Charge -1 This species takes part in two reactions (as a reactant in R PDE4 and as a product in R GUACYC). d M 35cgmp c = v − v (2092) dt 511 756

7.43 Species M 3c2hmp c Name 3-Carboxy-2-hydroxy-4-methylpentanoate

Charge -2 This species takes part in two reactions (as a reactant in R IPMD, R IPPMIa). d M 3c2hmp c = −v − v (2093) dt 560 561

7.44 Species M 3c3hmp c Name 3-Carboxy-3-hydroxy-4-methylpentanoate

Charge -2 This species takes part in two reactions (as a product in R IPPMIb, R IPPS). d M 3c3hmp c = v + v (2094) dt 562 563

872 Produced by SBML2LATEX 7.45 Species M 3c4mop c Name 3-Carboxy-4-methyl-2-oxopentanoate

Charge -2 This species takes part in two reactions (as a reactant in R OMCDC and as a product in R IPMD). d M 3c4mop c = v − v (2095) dt 560 726

7.46 Species M 3ddgc c Name 3-Dehydro-2-deoxy-D-gluconate

Charge -1 This species takes part in one reaction (as a product in R DGC3D). d M 3ddgc c = v (2096) dt 215

7.47 Species M 3dhq c Name 3-Dehydroquinate

Charge -1 This species takes part in two reactions (as a reactant in R DHQD and as a product in R DHQS). d M 3dhq c = v − v (2097) dt 235 234

7.48 Species M 3dhsk c Name 3-Dehydroshikimate

Charge -1 This species takes part in two reactions (as a reactant in R SHK3Dr and as a product in R DHQD). d M 3dhsk c = v − v (2098) dt 234 912

7.49 Species M 3ig3p c Name C’-(3-Indolyl)-glycerol 3-phosphate

Charge -2 This species takes part in three reactions (as a reactant in R TRPS1, R TRPS3 and as a product in R IGPS). d M 3ig3p c = v − v − v (2099) dt 550 973 975

Produced by SBML2LATEX 873 7.50 Species M 3mob c

Name 3-Methyl-2-oxobutanoate

Charge -1

This species takes part in four reactions (as a reactant in R IPPS, R MOHMT and as a product in R DHAD1, R VALTA).

d M 3mob c = v + v − v − v (2100) dt 217 1019 563 627

7.51 Species M 3mop c

Name (S)-3-Methyl-2-oxopentanoate

Charge -1

This species takes part in two reactions (as a product in R DHAD2, R ILETA).

d M 3mop c = v + v (2101) dt 218 551

7.52 Species M 3pg c

Name 3-Phospho-D-glycerate

Charge -3

This species takes part in four reactions (as a reactant in R PGCD, R PGK and as a product in R GLYCK, R PGM).

d M 3pg c = v + v − v − v (2102) dt 485 777 771 773

7.53 Species M 3php c

Name 3-Phosphohydroxypyruvate

Charge -3

This species takes part in two reactions (as a reactant in R PSERT and as a product in R PGCD).

d M 3php c = v − v (2103) dt 771 851

874 Produced by SBML2LATEX 7.54 Species M 3psme c

Name 5-O-(1-Carboxyvinyl)-3-phosphoshikimate

Charge -4

This species takes part in two reactions (as a reactant in R CHORS and as a product in R PSCVT).

d M 3psme c = v − v (2104) dt 848 143

7.55 Species M 4abut c

Name 4-Aminobutanoate

Charge 0

This species takes part in two reactions (as a reactant in R ABTA and as a product in R GLUDC).

d M 4abut c = v − v (2105) dt 475 8

7.56 Species M 4abz c

Name 4-Aminobenzoate

Charge -1

This species takes part in three reactions (as a reactant in R DHPS2, R FOLD3 and as a product in R ADCL).

d M 4abz c = v − v − v (2106) dt 32 233 413

7.57 Species M 4adcho c

Name 4-amino-4-deoxychorismate

Charge -1

This species takes part in two reactions (as a reactant in R ADCL and as a product in R ADCS).

d M 4adcho c = v − v (2107) dt 35 32

Produced by SBML2LATEX 875 7.58 Species M 4ahmmp c

Name 4-Amino-5-hydroxymethyl-2-methylpyrimidine

Charge 0

This species takes part in six reactions (as a reactant in R HMPK1, R HMPK2, R HMPK3, R HMPK4 and as a product in R AHMMPS, R TMN).

d M 4ahmmp c = v + v − v − v − v − v (2108) dt 63 963 528 529 530 531

7.59 Species M 4ampm c

Name 4-Amino-2-methyl-5-phosphomethylpyrimidine

Charge -2

This species takes part in ﬁve reactions (as a reactant in R PMPK and as a product in R HMPK1, R HMPK2, R HMPK3, R HMPK4).

d M 4ampm c = v + v + v + v − v (2109) dt 528 529 530 531 806

7.60 Species M 4c2me c

Name 4-(cytidine 5’-diphospho)-2-C-methyl-D-erythritol

Charge -2

This species takes part in two reactions (as a reactant in R CDPMEK and as a product in R MEPCT).

d M 4c2me c = v − v (2110) dt 604 137

7.61 Species M 4h2opntn c

Name 4-Hydroxy-2-oxopentanoate

Charge -1

This species takes part in one reaction (as a reactant in R HOPNTAL).

d M 4h2opntn c = −v (2111) dt 532

876 Produced by SBML2LATEX 7.62 Species M 4hba c Name 4-Hydroxy-benzyl alcohol

Charge 0 This species takes part in two reactions (as a product in R THZPSN, R THZSN). d M 4hba c = v + v (2112) dt 950 951

7.63 Species M 4hbzACP c Name 4-hydroxybenzoyl ACP

Charge -1 This species takes part in two reactions (as a reactant in R FASPHDCA and as a product in R- AACPS11). d M 4hbzACP c = v − v (2113) dt 6 377

7.64 Species M 4hbz c Name 4-Hydroxybenzoate

Charge -1 This species takes part in two reactions (as a reactant in R AACPS11 and as a product in R CHRPL). d M 4hbz c = v − v (2114) dt 144 6

7.65 Species M 4hthr c Name 4-Hydroxy-L-threonine

Charge 0 This species takes part in one reaction (as a product in R 4HTHRS). d M 4hthr c = v (2115) dt 3

7.66 Species M 4mhetz c Name 4-Methyl-5-(2-hydroxyethyl)-thiazole

Charge 0 This species takes part in two reactions (as a product in R THZSN, R TMN). d M 4mhetz c = v + v (2116) dt 951 963

Produced by SBML2LATEX 877 7.67 Species M 4mop c Name 4-Methyl-2-oxopentanoate

Charge -1 This species takes part in two reactions (as a product in R LEUTA, R OMCDC). d M 4mop c = v + v (2117) dt 571 726

7.68 Species M 4mpetz c Name 4-Methyl-5-(2-phosphoethyl)-thiazole

Charge -2 This species takes part in two reactions (as a reactant in R TMPPP and as a product in R THZPSN). d M 4mpetz c = v − v (2118) dt 950 965

7.69 Species M 4pasp c Name 4-Phospho-L-aspartate

Charge -2 This species takes part in two reactions (as a product in R ASAD, R ASPK). d M 4pasp c = v + v (2119) dt 104 110

7.70 Species M 4per c Name 4-Phospho-D-erythronate

Charge -3 This species takes part in two reactions (as a reactant in R PERD and as a product in R E4PD). d M 4per c = v − v (2120) dt 252 767

7.71 Species M 4ppan c Name D-4’-Phosphopantothenate

Charge -3 This species takes part in four reactions (as a reactant in R PPNCL, R PPNCL2, R PPNCL3 and as a product in R PNTK). d M 4ppan c = v − v − v − v (2121) dt 808 821 822 823

878 Produced by SBML2LATEX 7.72 Species M 4ppcys c

Name N-((R)-4-Phosphopantothenoyl)-L-cysteine

Charge -3

This species takes part in four reactions (as a reactant in R PPCDC and as a product in R PPNCL, R PPNCL2, R PPNCL3).

d M 4ppcys c = v + v + v − v (2122) dt 821 822 823 812

7.73 Species M 4r5au c

Name 4-(1-D-Ribitylamino)-5-aminouracil

Charge 0

This species takes part in three reactions (as a reactant in R RBFSa and as a product in R PMDPHT, R RBFSb).

d M 4r5au c = v + v − v (2123) dt 805 877 876

7.74 Species M 5aizc c

Name 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

Charge -3

This species takes part in three reactions (as a reactant in R AIRC3, R PRASCS and as a product in R AIRCr).

d M 5aizc c = v − v − v (2124) dt 68 67 834

7.75 Species M 5aop c

Name 5-Amino-4-oxopentanoate

Charge 0

This species takes part in two reactions (as a reactant in R PPBNGS and as a product in R G1SATi).

d M 5aop c = v − 2v (2125) dt 441 811

Produced by SBML2LATEX 879 7.76 Species M 5aprbu c Name 5-Amino-6-(5’-phosphoribitylamino)uracil

Charge -2 This species takes part in two reactions (as a reactant in R PMDPHT and as a product in R APRAUR). d M 5aprbu c = v − v (2126) dt 90 805

7.77 Species M 5apru c Name 5-Amino-6-(5’-phosphoribosylamino)uracil

Charge -2 This species takes part in three reactions (as a reactant in R APRAUR and as a product in R- DHPPDA, R DHPPDA2). d M 5apru c = v + v − v (2127) dt 231 232 90

7.78 Species M 5caiz c Name 5-phosphoribosyl-5-carboxyaminoimidazole

Charge -3 This species takes part in two reactions (as a product in R AIRC2, R AIRC3). d M 5caiz c = v + v (2128) dt 66 67

7.79 Species M 5dglcn c Name 5-Dehydro-D-gluconate

Charge -1 This species takes part in one reaction (as a reactant in R 5DGLCNR). d M 5dglcn c = −v (2129) dt 4

7.80 Species M 5fthf c Name 5-Formyltetrahydrofolate

Charge -2 This species takes part in two reactions (as a reactant in R FOMETR, R FTHFCL). d M 5fthf c = −v − v (2130) dt 415 425

880 Produced by SBML2LATEX 7.81 Species M 5mta c Name 5-Methylthioadenosine

Charge 0 This species takes part in two reactions (as a reactant in R MTAN and as a product in R SPMS). d M 5mta c = v − v (2131) dt 918 634

7.82 Species M 5mthf c Name 5-Methyltetrahydrofolate

Charge -1 This species takes part in two reactions (as a reactant in R METS and as a product in R MTHFR2). d M 5mthf c = v − v (2132) dt 638 608

7.83 Species M 5mtr c Name 5-Methylthio-D-ribose

Charge 0 This species takes part in one reaction (as a product in R MTAN). d M 5mtr c = v (2133) dt 634

7.84 Species M 5odhf2a c Name 5-Oxo-4,5-dihydrofuran-2-acetate

Charge -1 This species takes part in one reaction (as a product in R CMLDC). d M 5odhf2a c = v (2134) dt 152

7.85 Species M 5oxpro c Name 5-Oxoproline

Charge -1 This species takes part in two reactions (as a reactant in R OPAH and as a product in R GGLUCT2). d M 5oxpro c = v − v (2135) dt 462 728

Produced by SBML2LATEX 881 7.86 Species M 5prdmbz c Name N1-(5-Phospho-alpha-D-ribosyl)-5,6-dimethylbenzimidazole

Charge -2 This species takes part in two reactions (as a reactant in R RZ5PP and as a product in R NNDMBRT). d M 5prdmbz c = v − v (2136) dt 689 891

7.87 Species M 6hmhpt c Name 6-hydroxymethyl dihydropterin

Charge 0 This species takes part in two reactions (as a reactant in R HPPK2 and as a product in R DHNPA2). d M 6hmhpt c = v − v (2137) dt 226 534

7.88 Species M 6hmhptpp c Name 6-hydroxymethyl-dihydropterin pyrophosphate

Charge -3 This species takes part in two reactions (as a reactant in R DHPS2 and as a product in R HPPK2). d M 6hmhptpp c = v − v (2138) dt 534 233

7.89 Species M 6pgc c Name 6-Phospho-D-gluconate

Charge -3 This species takes part in two reactions (as a reactant in R GND and as a product in R PGL). d M 6pgc c = v − v (2139) dt 774 498

7.90 Species M 6pgl c Name 6-phospho-D-glucono-1,5-lactone

Charge -2 This species takes part in two reactions (as a reactant in R PGL and as a product in R G6PDH2). d M 6pgl c = v − v (2140) dt 448 774

882 Produced by SBML2LATEX 7.91 Species M 8aonn c Name 8-Amino-7-oxononanoate

Charge 0

This species takes part in two reactions (as a reactant in R AMAOTr and as a product in R AOXSr). d M 8aonn c = v − v (2141) dt 88 80

7.92 Species M ACP c Name acyl carrier protein

Charge -1

This species takes part in 24 reactions (as a reactant in R AACPS10, R AACPS11, R AACPS3, R ARACHTA, R MCOATA, R PHDCATA, R PREPTTA and as a product in R ACPS1, R AGPAT160, R AGPAT160190, R AGPAT190, R FAMPL1, R FAMPL2, R FAMPL3, R FAMPL4, R FAMPL5, R- FASPHDCA, R G3PAT160, R G3PAT190, R MYCSacp50, R MYCSacp56, R MYCSacp58, R PREPHACPH, R PREPPACPH). d M ACP c = v + v + v + v + v + v + v + v + v + 8v + v + v dt 27 57 58 59 356 357 358 359 360 377 442 443 + 11v660 + 14v661 + 15v662 + v837 + v838 − v5 − v6 − v7 − v93 − v597 − v786 − v841 (2142)

7.93 Species M Ac1PIM1 c Name acyl phosphatidylinositol mannoside (tuberculosis)

Charge -1

This species takes part in three reactions (as a reactant in R G16MTM2, R biomass Mtb 9 60atp and as a product in R MANAT1). d M Ac1PIM1 c = v − v − 0.001681v (2143) dt 590 432 1025

7.94 Species M Ac1PIM2 c Name acyl phosphatidylinositol mannoside di-mannose (tuberculosis)

Charge -1

This species takes part in ﬁve reactions (as a reactant in R G16MTM4, R MANAT3, R biomass- Mtb 9 60atp and as a product in R G16MTM2, R MANAT2). d M Ac1PIM2 c = v + v − v − v − 0.001488v (2144) dt 432 591 433 592 1025

Produced by SBML2LATEX 883 7.95 Species M Ac1PIM3 c

Name acyl phosphatidylinositol mannoside tri-mannose (tuberculosis)

Charge -1

This species takes part in three reactions (as a reactant in R G16MTM5, R biomass Mtb 9 60atp and as a product in R G16MTM4).

d M Ac1PIM3 c = v − v − 0.001335v (2145) dt 433 434 1025

7.96 Species M Ac1PIM4 c

Name acyl phosphatidylinositol mannoside tetra-mannose (tuberculosis)

Charge -1

This species takes part in two reactions (as a reactant in R biomass Mtb 9 60atp and as a product in R G16MTM5).

d M Ac1PIM4 c = v − 0.001211v (2146) dt 434 1025

7.97 Species M Ac2PIM2 c

Name di-acyl phosphatidylinositol mannoside di-mannose (tuberculosis)

Charge -1

This species takes part in two reactions (as a reactant in R biomass Mtb 9 60atp and as a product in R MANAT3).

d M Ac2PIM2 c = v − 0.001274v (2147) dt 592 1025

7.98 Species M PIM1 c

Name phosphatidylinositol mannoside (tuberculosis)

Charge -1

This species takes part in four reactions (as a reactant in R G16MTM6, R MANAT1, R biomass- Mtb 9 60atp and as a product in R G16MTM1).

d M PIM1 c = v − v − v − 0.002076v (2148) dt 430 435 590 1025

884 Produced by SBML2LATEX 7.99 Species M PIM2 c

Name phosphatidylinositol mannoside di-mannose (tuberculosis)

Charge -1

This species takes part in four reactions (as a reactant in R G16MTM7, R MANAT2, R biomass- Mtb 9 60atp and as a product in R G16MTM6).

d M PIM2 c = v − v − v − 0.00179v (2149) dt 435 436 591 1025

7.100 Species M PIM3 c

Name phosphatidylinositol mannoside tri-mannose (tuberculosis)

Charge -1

This species takes part in three reactions (as a reactant in R G16MTM8, R biomass Mtb 9 60atp and as a product in R G16MTM7).

d M PIM3 c = v − v − 0.001573v (2150) dt 436 437 1025

7.101 Species M PIM4 c

Name phosphatidylinositol mannoside tetra-mannose (tuberculosis)

Charge -1

This species takes part in three reactions (as a reactant in R G16MTM9, R biomass Mtb 9 60atp and as a product in R G16MTM8).

d M PIM4 c = v − v − 0.001403v (2151) dt 437 438 1025

7.102 Species M PIM5 c

Name phosphatidylinositol mannoside penta-mannose (tuberculosis)

Charge -1

This species takes part in three reactions (as a reactant in R G16MTM10, R biomass Mtb 9- 60atp and as a product in R G16MTM9).

d M PIM5 c = v − v − 0.001266v (2152) dt 438 431 1025

Produced by SBML2LATEX 885 7.103 Species M PIM6 c

Name phosphatidylinositol mannoside hexa-mannose (tuberculosis)

Charge -1

This species takes part in two reactions (as a reactant in R biomass Mtb 9 60atp and as a product in R G16MTM10).

d M PIM6 c = v − 0.001154v (2153) dt 431 1025

7.104 Species M aacoa c

Name Acetoacetyl-CoA

Charge -4

This species takes part in three reactions (as a product in R ACACCT, R ACACT1r, R OCOAT1r).

d M aacoa c = v + v + v (2154) dt 9 10 723

7.105 Species M ac c

Name Acetate

Charge -1

This species takes part in 13 reactions (as a reactant in R ACKr, R ACS and as a product in R- ACACCT, R ACODA, R AGDC, R ALDD2x, R AMID4, R CITL, R CITLr, R CYSS, R IGAMD, R LO, R R05219).

d M ac c = v +v +v +v +v +v +v +v +v +v +v −v −v (2155) dt 9 23 55 79 81 146 147 176 548 573 873 21 28

7.106 Species M acac c

Name Acetoacetate

Charge -1

This species takes part in three reactions (as a reactant in R ACACCT, R OCOAT1r and as a product in R BDH).

d M acac c = v − v − v (2156) dt 121 9 723

886 Produced by SBML2LATEX 7.107 Species M acald c Name Acetaldehyde

Charge 0

This species takes part in ﬁve reactions (as a reactant in R ACALDi, R ALDD2x and as a product in R DRPA, R HOPNTAL, R PYRDC). d M acald c = v + v + v − v − v (2157) dt 244 532 868 11 79

7.108 Species M accoa c Name Acetyl-CoA

Charge -4

This species takes part in 25 reactions (as a reactant in R ACACCT, R ACACT1r, R ACCOACr, R ACGS, R CS, R FAS80 L, R G1PACT, R HSERTA, R IPPS, R MALS, R MSHS, R PTAr, R SERAT and as a product in R ACALDi, R ACS, R FAO1, R FAO10, R FAO11, R FAO2, R FAO3, R MCD, R MMSAD3, R PDH, R PDHbr, R PFL). d M accoa c = v +v +7v +9v +8v +8v +9v +v +v +v +v +v dt 11 28 361 362 363 364 365 596 623 757 759 769 −v9 −2v10 −v14 −v19 −v168 −v376 −v439 −v537 −v563 −v582 −v633 −v855 −v899 (2158)

7.109 Species M acg5p c Name N-Acetyl-L-glutamyl 5-phosphate

Charge -3

This species takes part in two reactions (as a product in R ACGK, R AGPR). d M acg5p c = v + v (2159) dt 18 60

7.110 Species M acg5sa c Name N-Acetyl-L-glutamate 5-semialdehyde

Charge -1

This species takes part in two reactions (as a reactant in R AGPR and as a product in R ACOTA). d M acg5sa c = v − v (2160) dt 25 60

Produced by SBML2LATEX 887 7.111 Species M acgam1p c

Name N-Acetyl-D-glucosamine 1-phosphate

Charge -2

This species takes part in four reactions (as a reactant in R UAGDP, R biomass Mtb 9 60atp and as a product in R ACGAMPM, R G1PACT).

d M acgam1p c = v + v − v − 0.230181v (2161) dt 16 439 986 1025

7.112 Species M acgam6p c

Name N-Acetyl-D-glucosamine 6-phosphate

Charge -2

This species takes part in two reactions (as a reactant in R ACGAMPM, R AGDC).

d M acgam6p c = −v − v (2162) dt 16 55

7.113 Species M acgam c

Name N-Acetyl-D-glucosamine

Charge 0

This species takes part in one reaction (as a reactant in R IACGAMS).

d M acgam c = −v (2163) dt 542

7.114 Species M acglu c

Name N-Acetyl-L-glutamate

Charge -2

This species takes part in three reactions (as a reactant in R ACGK and as a product in R ACGS, R ORNTAC).

d M acglu c = v + v − v (2164) dt 19 730 18

888 Produced by SBML2LATEX 7.115 Species M achms c Name O-Acetyl-L-homoserine

Charge 0 This species takes part in one reaction (as a product in R HSERTA). d M achms c = v (2165) dt 537

7.116 Species M acorn c Name N2-Acetyl-L-ornithine

Charge 0 This species takes part in three reactions (as a reactant in R ACODA, R ACOTA, R ORNTAC). d M acorn c = −v − v − v (2166) dt 23 25 730

7.117 Species M acser c Name O-Acetyl-L-serine

Charge 0 This species takes part in two reactions (as a reactant in R CYSS and as a product in R SERAT). d M acser c = v − v (2167) dt 899 176

7.118 Species M actp c Name Acetyl phosphate

Charge -2 This species takes part in two reactions (as a product in R ACKr, R PTAr). d M actp c = v + v (2168) dt 21 855

7.119 Species M acysbmn c Name acetyl-cystine-bimane

Charge -1 This species takes part in two reactions (as a reactant in R ACYSBMNt and as a product in R- MSHAMID). d M acysbmn c = v − v (2169) dt 631 30

Produced by SBML2LATEX 889 7.120 Species M acysbmn e

Name acetyl-cystine-bimane

Charge -1

This species takes part in two reactions (as a reactant in R EX acysbmn e and as a product in R ACYSBMNt).

d M acysbmn e = v − v (2170) dt 30 257

7.121 Species M ad c

Name acetamide

Charge 0

This species takes part in one reaction (as a reactant in R AMID4).

d M ad c = −v (2171) dt 81

7.122 Species M adcobdam c

Name Adenosyl cobyrinate diamide

Charge -4

This species takes part in two reactions (as a reactant in R ADCYRS and as a product in R- CYRDAAT).

d M adcobdam c = v − v (2172) dt 174 36

7.123 Species M adcobhex c

Name adenosyl-cobyric acid

Charge 0

This species takes part in three reactions (as a reactant in R ADCPS1, R ADCPS2 and as a product in R ADCYRS).

d M adcobhex c = v − v − v (2173) dt 36 33 34

890 Produced by SBML2LATEX 7.124 Species M ade c

Name Adenine

Charge 0

This species takes part in ﬁve reactions (as a reactant in R ADPT and as a product in R AHCYSNS, R MTAN, R PUNP1, R PUNP2).

d M ade c = v + v + v + v − v (2174) dt 62 634 857 858 48

7.125 Species M adfdOX c

Name Oxidized adrenal ferredoxin

Charge 2

This species takes part in three reactions (as a reactant in R CODH3 and as a product in R FRDO2r, R FRDO3r).

d M adfdOX c = v + v − v (2175) dt 421 422 158

7.126 Species M adfdRD c

Name Reduced adrenal ferredoxin

Charge 0

This species takes part in three reactions (as a reactant in R FRDO2r, R FRDO3r and as a product in R CODH3).

d M adfdRD c = v − v − v (2176) dt 158 421 422

7.127 Species M adhlam c

Name S-Acetyldihydrolipoamide

Charge 0

This species takes part in two reactions (as a reactant in R PDHbr and as a product in R PDHa).

d M adhlam c = v − v (2177) dt 758 759

Produced by SBML2LATEX 891 7.128 Species M adn c

Name Adenosine

Charge 0

This species takes part in seven reactions (as a reactant in R ADA, R ADNK1, R ADNK3, R ADNK4, R PUNP1 and as a product in R AHC, R NTD7).

d M adn c = v + v − v − v − v − v − v (2178) dt 61 705 31 43 44 45 857

7.129 Species M adocbi c

Name Adenosyl cobinamide

Charge 1

This species takes part in three reactions (as a reactant in R ADOCBIK and as a product in R- ADCPS1, R CBIAT).

d M adocbi c = v + v − v (2179) dt 33 131 46

7.130 Species M adocbip c

Name Adenosyl cobinamide phosphate

Charge -1

This species takes part in three reactions (as a reactant in R ACBIPGT and as a product in R- ADCPS2, R ADOCBIK).

d M adocbip c = v + v − v (2180) dt 34 46 12

7.131 Species M adocbl c

Name Adenosylcobalamin

Charge 0

This species takes part in two reactions (as a product in R ADOCBLS, R CBLAT).

d M adocbl c = v + v (2181) dt 47 132

892 Produced by SBML2LATEX 7.132 Species M adp c Name ADP

Charge -3

This species takes part in 134 reactions (as a reactant in R ATPS4r, R PYK, R RNDR1 and as a product in R ACCOACr, R ACGK, R ACKr, R ADCPS1, R ADCPS2, R ADCYRS, R ADK1, R ADK2, R- ADK3, R ADK4, R ADNK1, R ADOCBIK, R ADSK, R AICART2, R AIRC2, R ALAALAr, R ARB Dabc, R ARBabc, R ASPK, R ATPS1, R CAATPS, R CBPS, R CDPMEK, R CHLabc, R CITabc, R COCHL, R CRNabc, R CTPS1, R CTPS2, R CYTK1, R CYTK2, R Cuabc, R Cut1, R DADK, R DAGK160, R- DBTSr, R DGK1, R DHFS, R DPCOAK, R DTMPK, R DURIK1, R FE2abc, R FE3abc, R FTHFCL, R FTHFL, R GALKr, R GK1, R GLCS1, R GLCabc, R GLNS, R GLNSP1, R GLNSP2, R GLNSP3, R- GLU5K, R GLUCYS, R GLYBabc, R GLYC3Pabc, R GLYCK, R GLYK, R GSNK, R GTHS, R HEX1, R- HMPK1, R HSK, R INSK, R Kabc, R LCTSabc, R MALTHPabc, R MALTabc, R MCBTS, R MCBTS2, R MCBTS3, R METabc, R MPML, R NADK, R NDPK1, R NDPK2, R NDPK3, R NDPK4, R NDPK5, R- NDPK6, R NDPK7, R NDPK8, R NDPK9, R OPAH, R PC, R PFK, R PGK, R PIabc, R PMPK, R PNTK, R PPCKr, R PPCOAC, R PPK2, R PRAGSr, R PRAIS, R PRASCS, R PRFGS, R PROabc, R R05224, R RBFK, R RBK, R RBK Dr, R RBK L1r, R RIBabc, R SHKK, R SUCOAS, R SULabc, R THFGLUS, R TMDK1, R TMPKr, R TREabc, R TSULabc, R UAAGDS, R UAAGLS1, R UAAGLS2, R UAMAGS, R- UAMAS, R UGAGDS, R UGLDDS1, R UGLDDS2, R UGMAGS, R UGMAS, R UGMDDS, R UGMDDS2, R- UMPK, R URIDK1, R URIDK2r, R XYLK, R XYLabc, R biomass Mtb 9 60atp). d M adp c = v + v + v + v + v + 4v + 2v + v + v + v + v + v + v + v dt 14 18 21 33 34 36 37 38 39 40 43 46 49 65 +v66 +v71 +v95 +v96 +v110 +v117 +v128 +2v133 +v137 +v140 +v148 +v156 +v167 + v169 + v170 + v185 + v186 + v188 + v189 + v191 + v192 + v201 + v216 + v222 + v241 + v246 + v247 + v406 + v408 + v425 + v427 + v450 + v464 + v466 + v467 + v469 + v470 + v471 + v472 + v473 + v474 + v483 + v484 + v485 + v492 + v501 + v504 + v523 + v528 + v538 + v557 + v566 + v569 + v584 + v585 + v593 + v594 + v595 + v611 + v630 + v669 + v676 + v677 + v678 + v679 + v680 + v681 + v682 + v683 + v684 + v728 + v748 + v768 + v773 + v799 + v806 + v808 + v813 + v814 + v820 + v830 + v831 + v834 + v842 + v845 + 2v874 + v875 + v878 + v879 + v880 + v881 + v913 + v926 + v928 + v944 + v954 + v964 +v971 +v978 +v982 +v983 +v984 +v990 +v991 +v1001 +v1003 +v1004 +v1005 +v1006 +v1007 +v1008 +v1009 +v1016 +v1017 +v1022 +v1023 +60v1025 −v118 −v867 −v882 (2182)

7.133 Species M adpglc c Name ADPglucose

Charge -2

This species takes part in two reactions (as a reactant in R GLCS1 and as a product in R GLGC). d M adpglc c = v − v (2183) dt 468 466

Produced by SBML2LATEX 893 7.134 Species M agalfragund c Name arabinofuranose-galactofuranosyl(30)-rhamanosyl-N-acetylglucosamyl-undecaprenyl diphosphate (M tb)

Charge -2 This species takes part in two reactions (as a reactant in R AFE and as a product in R AFTA). d M agalfragund c = v − v (2184) dt 54 53

7.135 Species M agdpcbi c Name Adenosine-GDP-cobinamide

Charge -1 This species takes part in two reactions (as a reactant in R ADOCBLS and as a product in R- ACBIPGT). d M agdpcbi c = v − v (2185) dt 12 47

7.136 Species M agm c Name Agmatine

Charge 2 This species takes part in two reactions (as a reactant in R AGMT and as a product in R ARGDC). d M agm c = v − v (2186) dt 98 56

7.137 Species M ahcys c Name S-Adenosyl-L-homocysteine

Charge 0 This species takes part in 29 reactions (as a reactant in R AHC, R AHCYSNS and as a product in R AMMQT6, R AMMQT8, R AMMQT8 2, R CPC2MT, R CPC3MT, R CPC4MT, R CPC6MT, R HCYSMT, R MYC1CYC1, R MYC1CYC2, R MYC1CYC3, R MYC1CYC4, R MYC1CYC5, R MYC1M1, R MYC1M2, R- MYC2CYC1, R MYC2CYC2, R MYC2CYC3, R PC11M, R PC17M, R PC20M, R PC6YM, R PGLS, R- PHTHS, R PHTHS2, R R05219, R UPP3MT). d M ahcys c = v + v + v + v + v + v + 2v + v + v + v dt 82 83 84 160 161 162 163 521 640 641 + v642 + v643 + v644 + v645 + v646 + v647 + v648 + v649 + v749 + v750 + v751 + 2v753 + 4v775 + v795 + v796 + v873 + 2v1010 − v61 − v62 (2187)

894 Produced by SBML2LATEX 7.138 Species M ahdt c Name 2-Amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)dihydropteridine triphosphate

Charge -4

This species takes part in two reactions (as a reactant in R DNTPPA and as a product in R GTPCI). d M ahdt c = v − v (2188) dt 506 240

7.139 Species M aicar c Name 5-Amino-1-(5-Phospho-D-ribosyl)imidazole-4-carboxamide

Charge -2

This species takes part in four reactions (as a reactant in R AICART, R AICART2 and as a product in R ADSL2r, R IG3PS). d M aicar c = v + v − v − v (2189) dt 51 547 64 65

7.140 Species M air c Name 5-amino-1-(5-phospho-D-ribosyl)imidazole

Charge -2

This species takes part in four reactions (as a reactant in R AHMMPS, R AIRC2, R AIRCr and as a product in R PRAIS). d M air c = v − v − v − v (2190) dt 831 63 66 68

7.141 Species M akg c Name 2-Oxoglutarate

Charge -2

This species takes part in 21 reactions (as a reactant in R ABTA, R ACOTA, R ALATA L, R ASPTA, R GLUSy, R ILETA, R LEUTA, R ORNTA, R OXGDC, R OXGDC2, R PHETA1, R SDPTA, R SOTA, R- TRPTA, R TYRTA, R VALTA and as a product in R GLUDx, R HSTPT, R ICDHy, R OHPBAT, R- PSERT).

d M akg c = v + v + v + v + v − v − v − v − v − v − v dt 476 540 543 725 851 8 25 74 113 479 551 (2191) − v571 − v729 − v735 − v736 − v788 − v897 − v917 − v976 − v980 − v1019

Produced by SBML2LATEX 895 7.142 Species M ala DASH B c

Name beta-Alanine

Charge 0

This species takes part in four reactions (as a reactant in R APATr, R PANTS and as a product in R ASP1DC, R BALAt2r).

d M ala DASH B c = v + v − v − v (2192) dt 108 120 89 741

7.143 Species M ala DASH B e

Name beta-Alanine

Charge 0

This species takes part in two reactions (as a reactant in R BALAt2r, R EX ala DASH B e).

d M ala DASH B e = −v − v (2193) dt 120 258

7.144 Species M ala DASH D c

Name D-Alanine

Charge 0

This species takes part in ﬁve reactions (as a reactant in R ALAALAr, R DALAOX and as a product in R ALAALAD, R ALAR, R DALAt2r).

d M ala DASH D c = 2v + v + v − 2v − v (2194) dt 70 73 194 71 193

7.145 Species M ala DASH D e

Name D-Alanine

Charge 0

This species takes part in two reactions (as a reactant in R DALAt2r, R EX ala DASH D e).

d M ala DASH D e = −v − v (2195) dt 194 259

896 Produced by SBML2LATEX 7.146 Species M ala DASH L c

Name L-Alanine

Charge 0

This species takes part in 15 reactions (as a reactant in R ALAD L, R ALAR, R ALATA L, R- ALATRS, R AOXSr, R GTMLT, R UAMAS, R UGMAS, R biomass Mtb 9 60atp and as a product in R ALAt2r, R APATr, R BTS2, R GGLUCT2, R SELCYSLY, R THZPSN).

d M ala DASH L c = v + v + v + v + v + v − v − v − v dt 76 89 126 462 898 950 72 73 74 (2196) − v75 − v88 − v505 − v991 − v1006 − 0.405957v1025

7.147 Species M ala DASH L e

Name L-Alanine

Charge 0

This species takes part in two reactions (as a reactant in R ALAt2r, R EX ala DASH L e).

d M ala DASH L e = −v − v (2197) dt 76 260

7.148 Species M alaala c

Name D-Alanyl-D-alanine

Charge 0

This species takes part in six reactions (as a reactant in R ALAALAD, R UGLDDS1, R UGLDDS2, R UGMDDS, R UGMDDS2 and as a product in R ALAALAr).

d M alaala c = v − v − v − v − v − v (2198) dt 71 70 1003 1004 1007 1008

7.149 Species M alac DASH S c

Name (S)-2-Acetolactate

Charge -1

This species takes part in two reactions (as a reactant in R KARA1i and as a product in R ACLS).

d M alac DASH S c = v − v (2199) dt 22 564

Produced by SBML2LATEX 897 7.150 Species M alatrna c Name L-Alanyl-tRNA(Ala)

Charge 1

This species takes part in one reaction (as a product in R ALATRS). d M alatrna c = v (2200) dt 75

7.151 Species M alpam c Name S-aminomethyldihydrolipoamide

Charge 1

This species takes part in one reaction (as a reactant in R GCC2). d M alpam c = −v (2201) dt 456

7.152 Species M alpro c Name S-Aminomethyldihydrolipoylprotein

Charge 1

This species takes part in two reactions (as a reactant in R GCCb and as a product in R GCCa). d M alpro c = v − v (2202) dt 457 458

7.153 Species M amet c Name S-Adenosyl-L-methionine

Charge 1

This species takes part in 30 reactions (as a reactant in R ADMDCr, R AMAOTr, R AMMQT6, R- AMMQT8, R AMMQT8 2, R CPC2MT, R CPC3MT, R CPC4MT, R CPC6MT, R HCYSMT, R MYC1CYC1, R MYC1CYC2, R MYC1CYC3, R MYC1CYC4, R MYC1CYC5, R MYC1M1, R MYC1M2, R MYC2CYC1, R- MYC2CYC2, R MYC2CYC3, R PC11M, R PC17M, R PC20M, R PC6YM, R PGLS, R PHTHS, R PHTHS2, R R05219, R UPP3MT and as a product in R METAT). d M amet c = v − v − v − v − v − v − v − v − v − 2v − v dt 605 41 80 82 83 84 160 161 162 163 521 − v640 − v641 − v642 − v643 − v644 − v645 − v646 − v647 − v648 − v649 − v749 − v750 − v751 − 2v753 − 4v775 − v795 − v796 − v873 − 2v1010 (2203)

898 Produced by SBML2LATEX 7.154 Species M ametam c

Name S-Adenosylmethioninamine

Charge 2

This species takes part in two reactions (as a reactant in R SPMS and as a product in R ADMDCr).

d M ametam c = v − v (2204) dt 41 918

7.155 Species M amob c

Name S-Adenosyl-4-methylthio-2-oxobutanoate

Charge 0

This species takes part in one reaction (as a product in R AMAOTr).

d M amob c = v (2205) dt 80

7.156 Species M amp c

Name AMP

Charge -2

This species takes part in 62 reactions (as a reactant in R ADK1, R ADK2, R ADK3, R ADK4, R- FAMPL1, R FAMPL2, R FAMPL3, R FAMPL4, R FAMPL5, R NTD7, R biomass Mtb 9 60atp and as a product in R 2AGPEAT160, R 2AGPEAT180, R AACPS10, R AACPS11, R AACPS3, R ACS, R ACS2, R ADNK1, R ADNK3, R ADNK4, R ADPT, R ADSL1r, R ALATRS, R ARGSS, R ASNS1, R- BPNT, R CIGAMS, R ENTCS, R FACOAL140, R FACOAL160, R FACOAL161, R FACOAL180, R- FACOAL181, R FACOAL200, R FACOAL80, R FACOALPHDCA, R FACOALPREPH, R FAO1, R FAO10, R FAO11, R FAO2, R FAO3, R FORMCOAL, R GMPS2, R GTPDPK, R HPPK, R HPPK2, R MYCON1, R- MYCON2, R MYCON3, R MYCON4, R MYCON5, R NADS2, R OXACOAL, R PANTS, R PDE1, R PPDK, R PPNCL3, R PRPPS, R SUCBZL, R THZPSN).

d M amp c = v + v + v + v + v + v + v + v + v + v + v + v + v + v + v dt 1 2 5 6 7 28 29 43 44 45 48 50 75 101 106 + v125 + v145 + 6v255 + v346 + v347 + v348 + v349 + v350 + v351 + v352 + v353 + v354 + v361 + v362 + v363 + v364 + v365 + v416 + v495 + v509 + v533 + v534 + v655 + v656 + v657 + v658 + v659 + v670 + v733 + v741 + v755 + v818 + v823 + v847 + v922 + v950 − v37 − v38 − v39 − v40 − v356 − v357 − v358 − v359 − v360 − v705 − 0.139026v1025 (2206)

Produced by SBML2LATEX 899 7.157 Species M anth c Name Anthranilate

Charge -1 This species takes part in two reactions (as a reactant in R ANPRT and as a product in R ANS). d M anth c = v − v (2207) dt 87 86

7.158 Species M apoACP c Name apoprotein [acyl carrier protein]

Charge 0 This species takes part in one reaction (as a reactant in R ACPS1). d M apoACP c = −v (2208) dt 27

7.159 Species M appl c Name 1-Aminopropan-2-ol

Charge 1 This species takes part in one reaction (as a reactant in R ADCPS1). d M appl c = −v (2209) dt 33

7.160 Species M applp c Name D-1-Aminopropan-2-ol O-phosphate

Charge -1 This species takes part in one reaction (as a reactant in R ADCPS2). d M applp c = −v (2210) dt 34

7.161 Species M aps c Name Adenosine 5’-phosphosulfate

Charge -2 This species takes part in three reactions (as a reactant in R ADSK and as a product in R SADT, R SADT2). d M aps c = v + v − v (2211) dt 893 894 49

900 Produced by SBML2LATEX 7.162 Species M arab DASH D c

Name D-Arabinose

Charge 0

This species takes part in ﬁve reactions (as a reactant in R ARABF, R ARABI, R HAS, R TAS and as a product in R ARB Dabc).

d M arab DASH D c = v − 12v − v − v − v (2212) dt 95 91 92 519 932

7.163 Species M arab DASH D e

Name D-Arabinose

Charge 0

This species takes part in two reactions (as a reactant in R ARB Dabc, R EX arab DASH D e).

d M arab DASH D e = −v − v (2213) dt 95 261

7.164 Species M arab DASH L c

Name L-Arabinose

Charge 0

This species takes part in three reactions (as a reactant in R ARAI and as a product in R ARBabc, R ARBt2r).

d M arab DASH L c = v + v − v (2214) dt 96 97 94

7.165 Species M arab DASH L e

Name L-Arabinose

Charge 0

This species takes part in three reactions (as a reactant in R ARBabc, R ARBt2r, R EX arab- DASH L e).

d M arab DASH L e = −v − v − v (2215) dt 96 97 262

Produced by SBML2LATEX 901 7.166 Species M arabinan c

Name arabinan complex (Mtb)

Charge 0

This species takes part in two reactions (as a reactant in R AFE and as a product in R ARABF).

d M arabinan c = v − v (2216) dt 91 53

7.167 Species M arabinanagalfragund c

Name arabinan-arabinofuranose-galactofuranosyl(30)-rhamanosyl-N-acetylglucosamyl-undecaprenyl diphosphate (M tb)

Charge -2

This species takes part in two reactions (as a reactant in R biomass Mtb 9 60atp and as a product in R AFE).

d M arabinanagalfragund c = v − 7.31 · 10−4v (2217) dt 53 1025

7.168 Species M arachACP c

Name eicosanoyl-ACP (n-C20:0)

Charge -1

This species takes part in two reactions (as a reactant in R PREPTHS and as a product in R- ARACHTA).

d M arachACP c = v − v (2218) dt 93 839

7.169 Species M arach c

Name Arachidic acid

Charge -1

This species takes part in four reactions (as a reactant in R FACOAL200, R FASm220, R biomass- Mtb 9 60atp and as a product in R FAS200).

d M arach c = v − v − v − 0.015676v (2219) dt 373 351 383 1025

902 Produced by SBML2LATEX 7.170 Species M arachcoa c

Name arachidyl coenzyme A

Charge -4

This species takes part in two reactions (as a reactant in R ARACHTA and as a product in R- FACOAL200).

d M arachcoa c = v − v (2220) dt 351 93

7.171 Species M arg DASH L c

Name L-Arginine

Charge 1

This species takes part in six reactions (as a reactant in R ARGDC, R ARGDr, R AST, R biomass- Mtb 9 60atp and as a product in R ARGSL, R ARGt5r).

d M arg DASH L c = v + v − v − v − v − 0.120416v (2221) dt 100 102 98 99 115 1025

7.172 Species M arg DASH L e

Name L-Arginine

Charge 1

This species takes part in two reactions (as a reactant in R ARGt5r, R EX arg DASH L e).

d M arg DASH L e = −v − v (2222) dt 102 263

7.173 Species M argsuc c

Name N(omega)-(L-Arginino)succinate

Charge -1

This species takes part in two reactions (as a reactant in R ARGSL and as a product in R ARGSS).

d M argsuc c = v − v (2223) dt 101 100

Produced by SBML2LATEX 903 7.174 Species M arpp c

Name 5-phosphoarabinose pyrophosphate

Charge -5

This species takes part in two reactions (as a reactant in R ARI, R DCPT2).

d M arpp c = −v − v (2224) dt 103 208

7.175 Species M asn DASH L c

Name L-Asparagine

Charge 0

This species takes part in four reactions (as a reactant in R ASNN, R biomass Mtb 9 60atp and as a product in R ASNS1, R ASNt2r).

d M asn DASH L c = v + v − v − 0.047699v (2225) dt 106 107 105 1025

7.176 Species M asn DASH L e

Name L-Asparagine

Charge 0

This species takes part in two reactions (as a reactant in R ASNt2r, R EX asn DASH L e).

d M asn DASH L e = −v − v (2226) dt 107 264

7.177 Species M asp DASH L c

Name L-Aspartate

Charge -1

This species takes part in 13 reactions (as a reactant in R ADSS, R ARGSS, R ASNS1, R ASP1DC, R ASPCT, R ASPK, R ASPO1, R ASPO5, R ASPTA, R PRASCS, R biomass Mtb 9 60atp and as a product in R ASNN, R ASPt2r).

d M asp DASH L c = v + v − v − v − v − v − v dt 105 114 52 101 106 108 109 (2227) − v110 − v111 − v112 − v113 − v834 − 0.120308v1025

904 Produced by SBML2LATEX 7.178 Species M asp DASH L e

Name L-Aspartate

Charge -1

This species takes part in two reactions (as a reactant in R ASPt2r, R EX asp DASH L e). d M asp DASH L e = −v − v (2228) dt 114 265

7.179 Species M aspsa c

Name L-Aspartate 4-semialdehyde

Charge 0

This species takes part in four reactions (as a reactant in R ASAD, R DHDPS and as a product in R HSDx, R HSDy). d M aspsa c = v + v − v − v (2229) dt 535 536 104 220

7.180 Species M atp c

Name ATP

Charge -4

This species takes part in 181 reactions (as a reactant in R 2AGPEAT160, R 2AGPEAT180, R- AACPS10, R AACPS11, R AACPS3, R ACCOACr, R ACGK, R ACKr, R ACS, R ACS2, R ADCPS1, R- ADCPS2, R ADCYRS, R ADK1, R ADNCYC, R ADNK1, R ADOCBIK, R ADSK, R AICART2, R AIRC2, R ALAALAr, R ALATRS, R ARB Dabc, R ARBabc, R ARGSS, R ASNS1, R ASPK, R ATPPRT, R- ATPS1, R BACCL, R CAATPS, R CBIAT, R CBLAT, R CBPS, R CDPMEK, R CHLabc, R CIGAMS, R CITabc, R COCHL, R CRNabc, R CTPS1, R CTPS2, R CYRDAAT, R CYTK1, R CYTK2, R Cuabc, R Cut1, R DADK, R DAGK160, R DBTSr, R DGK1, R DHFS, R DM atp c, R DPCOAK, R DTMPK, R- DURIK1, R FACOAL140, R FACOAL160, R FACOAL161, R FACOAL180, R FACOAL181, R FACOAL200, R FACOAL80, R FACOALPHDCA, R FACOALPREPH, R FAO1, R FAO10, R FAO11, R FAO2, R FAO3, R FE2abc, R FE3abc, R FMNAT, R FORMCOAL, R FTHFCL, R FTHFL, R GALKr, R GK1, R GLCabc, R GLGC, R GLNS, R GLNSP1, R GLNSP2, R GLNSP3, R GLU5K, R GLUCYS, R GLYBabc, R GLYC3Pabc, R GLYCK, R GLYK, R GMPS2, R GSNK, R GTHS, R GTPDPK, R HEX1, R HMPK1, R HPPK, R HPPK2, R HSK, R INSK, R Kabc, R LCTSabc, R MALTHPabc, R MALTabc, R MCBTS, R MCBTS2, R MCBTS3, R METAT, R METabc, R MPML, R NADK, R NADS2, R NDPK1, R NDPK2, R NDPK3, R NDPK4, R- NDPK5, R NDPK6, R NDPK7, R NDPK8, R NDPK9, R NNAT, R OPAH, R OXACOAL, R PANTS, R PC, R PFK, R PGK, R PIabc, R PMPK, R PNTK, R PPCKr, R PPCOAC, R PPDK, R PPK2, R PPNCL3, R- PRAGSr, R PRAIS, R PRASCS, R PRFGS, R PROabc, R PRPPS, R PTPATi, R R05224, R RBFK, R RBK, R RBK Dr, R RBK L1r, R RIBabc, R SADT, R SADT2, R SHKK, R SUCBZL, R SUCOAS,

Produced by SBML2LATEX 905 R SULabc, R THFGLUS, R THZPSN, R TMDK1, R TMPKr, R TREabc, R TSULabc, R UAAGDS, R- UAAGLS1, R UAAGLS2, R UAMAGS, R UAMAS, R UGAGDS, R UGLDDS1, R UGLDDS2, R UGMAGS, R- UGMAS, R UGMDDS, R UGMDDS2, R UMPK, R URIDK1, R URIDK2r, R XYLK, R XYLabc, R biomass- Mtb 9 60atp and as a product in R ATPS4r, R PYK).

d M atp c = v + v − v − v − v − v − v − v − v − v − v − v − v − v − 4v dt 118 867 1 2 5 6 7 14 18 21 28 29 33 34 36 −v37 −v42 −v43 −v46 −v49 −v65 −v66 −v71 −v75 −v95 −v96 −v101 −v106 −v110 − v116 − v117 − v119 − v128 − v131 − v132 − 2v133 − v137 − v140 − v145 − v148 − v156 −v167 −v169 −v170 −v174 −v185 −v186 −v188 −v189 −v191 −v192 −v201 −v216 −v222 −v238 −v241 −v246 −v247 −v346 −v347 −v348 −v349 −v350 −v351 −v352 −v353 −v354 −v361 −v362 −v363 −v364 −v365 −v406 −v408 −v412 −v416 −v425 −v427 −v450 −v464 −v467 −v468 −v469 −v470 −v471 −v472 −v473 −v474 −v483 −v484 −v485 −v492 −v495 −v501 −v504 −v509 −v523 −v528 −v533 −v534 −v538 −v557 −v566 −v569 −v584 −v585 −v593 −v594 −v595 −v605 −v611 −v630 −v669 −v670 −v676 −v677 −v678 −v679 −v680 −v681 −v682 −v683 −v684 −v688 −v728 −v733 −v741 −v748 −v768 −v773 −v799 −v806 −v808 −v813 −v814 −v818 −v820 −v823 −v830 −v831 −v834 −v842 −v845 −v847 −v856 − 2v874 − v875 − v878 − v879 − v880 − v881 − v893 − v894 − v913 − v922 − v926 − v928 − v944 − v950 − v954 − v964 − v971 − v978 − v982 − v983 − v984 − v990 − v991 − v1001 −v1003 −v1004 −v1005 −v1006 −v1007 −v1008 −v1009 −v1016 −v1017 −v1022 −v1023 − 60v1025 (2230)

7.181 Species M atp e

Name ATP

Charge -4

This species takes part in one reaction (as a reactant in R EX atp e).

d M atp e = −v (2231) dt 266

7.182 Species M betald c

Name Betaine aldehyde

Charge 1

This species takes part in two reactions (as a reactant in R BETALDHx and as a product in R- CHOLD). d M betald c = v − v (2232) dt 141 122

906 Produced by SBML2LATEX 7.183 Species M bhb c Name (R)-3-Hydroxybutanoate

Charge -1 This species takes part in four reactions (as a reactant in R BDH, R MCBTS, R MCBTS2, R MCBTS3). d M bhb c = −v − v − v − v (2233) dt 121 593 594 595

7.184 Species M bmn c Name bimane

Charge 0 This species takes part in two reactions (as a reactant in R BMNMSHS, R BMNt). d M bmn c = −v − v (2234) dt 123 124

7.185 Species M bmn e Name bimane

Charge 0 This species takes part in two reactions (as a reactant in R EX bmn e and as a product in R BMNt). d M bmn e = v − v (2235) dt 124 267

7.186 Species M bmnmsh c Name bimane conjugated mycothiol (mtb)

Charge 0 This species takes part in two reactions (as a reactant in R MSHAMID and as a product in R- BMNMSHS). d M bmnmsh c = v − v (2236) dt 123 631

7.187 Species M btamp c Name Biotinyl-5’-AMP

Charge -1 This species takes part in one reaction (as a product in R BACCL). d M btamp c = v (2237) dt 119

Produced by SBML2LATEX 907 7.188 Species M btn c

Name Biotin

Charge -1

This species takes part in three reactions (as a reactant in R BACCL and as a product in R BTS2, R BTS3r).

d M btn c = v + v − v (2238) dt 126 127 119

7.189 Species M ca2 c

Name Calcium

Charge 2

This species takes part in two reactions (as a reactant in R CAATPS, R CAt4).

d M ca2 c = −2v − v (2239) dt 128 130

7.190 Species M ca2 e

Name Calcium

Charge 2

This species takes part in three reactions (as a reactant in R EX ca2 e and as a product in R- CAATPS, R CAt4).

d M ca2 e = 2v + v − v (2240) dt 128 130 268

7.191 Species M camp c

Name cAMP

Charge -1

This species takes part in two reactions (as a reactant in R PDE1 and as a product in R ADNCYC).

d M camp c = v − v (2241) dt 42 755

908 Produced by SBML2LATEX 7.192 Species M cbasp c

Name N-Carbamoyl-L-aspartate

Charge -2

This species takes part in two reactions (as a product in R ASPCT, R DHORTS).

d M cbasp c = v + v (2242) dt 109 230

7.193 Species M cbi c

Name Cobinamide

Charge 0

This species takes part in one reaction (as a reactant in R CBIAT).

d M cbi c = −v (2243) dt 131

7.194 Species M cbl1 c

Name Cob(I)alamin

Charge -1

This species takes part in one reaction (as a reactant in R CBLAT).

d M cbl1 c = −v (2244) dt 132

7.195 Species M cbp c

Name Carbamoyl phosphate

Charge -2

This species takes part in three reactions (as a reactant in R ASPCT, R OCBT and as a product in R CBPS).

d M cbp c = v − v − v (2245) dt 133 109 721

Produced by SBML2LATEX 909 7.196 Species M cdp c

Name CDP

Charge -3

This species takes part in ﬁve reactions (as a reactant in R NDPK3, R RNDR3 and as a product in R CYTK1, R HMPK2, R PPNCL).

d M cdp c = v + v + v − v − v (2246) dt 185 529 821 678 884

7.197 Species M cdpc16c19g c

Name cdp diacylglycerol (C16:0, C19:0)

Charge -2

This species takes part in four reactions (as a reactant in R CDAPPA160190, R CDPPT160190, R PGSA160190 and as a product in R DASYN160190).

d M cdpc16c19g c = v − v − v − v (2247) dt 198 135 139 784

7.198 Species M cdpc19c19g c

Name cdp diacylglycerol (C19:0, C19:0)

Charge -2

This species takes part in three reactions (as a reactant in R CDAPPA190, R PGSA190 and as a product in R DASYN190190).

d M cdpc19c19g c = v − v − v (2248) dt 199 136 785

7.199 Species M cdpdhdecg c

Name CDP-1,2-dihexadecanoylglycerol

Charge -2

This species takes part in ﬁve reactions (as a reactant in R CDAPPA160, R CDPPT160, R PGSA160, R PSSA160 and as a product in R DASYN160).

d M cdpdhdecg c = v − v − v − v − v (2249) dt 197 134 138 783 853

910 Produced by SBML2LATEX 7.200 Species M cdpdodecg c

Name CDP-1,2-dioctadecanoylglycerol

Charge -2

This species takes part in one reaction (as a reactant in R PSSA180).

d M cdpdodecg c = −v (2250) dt 854

7.201 Species M cgly c

Name Cys-Gly

Charge 0

This species takes part in two reactions (as a reactant in R AMPTASECG and as a product in R- GTMLT).

d M cgly c = v − v (2251) dt 505 85

7.202 Species M chexccoa c

Name carboxy hexacosanoyl-CoA

Charge -4

This species takes part in six reactions (as a reactant in R MYCON1, R MYCON2, R MYCON3, R- MYCON4, R MYCON5 and as a product in R ACCC).

d M chexccoa c = v − v − v − v − v − v (2252) dt 13 655 656 657 658 659

7.203 Species M chol c

Name Choline

Charge 1

This species takes part in two reactions (as a reactant in R CHOLD and as a product in R CHLabc).

d M chol c = v − v (2253) dt 140 141

Produced by SBML2LATEX 911 7.204 Species M chol e

Name Choline

Charge 1

This species takes part in two reactions (as a reactant in R CHLabc, R EX chol e).

d M chol e = −v − v (2254) dt 140 269

7.205 Species M chor c

Name chorismate

Charge -2

This species takes part in seven reactions (as a reactant in R ADCS, R ANS, R CHORM, R CHRPL, R ICHORSi, R SALCS and as a product in R CHORS).

d M chor c = v − v − v − v − v − v − v (2255) dt 143 35 87 142 144 544 895

7.206 Species M cigam c

Name cys-1D-myo-inositol 2-deoxy-D-glucopyranoside

Charge 0

This species takes part in two reactions (as a reactant in R MSHS and as a product in R CIGAMS).

d M cigam c = v − v (2256) dt 145 633

7.207 Species M cit c

Name Citrate

Charge -3

This species takes part in ﬁve reactions (as a reactant in R ACONT, R CITL, R CITLr and as a product in R CITabc, R CS).

d M cit c = v + v − v − v − v (2257) dt 148 168 24 146 147

912 Produced by SBML2LATEX 7.208 Species M cit e

Name Citrate

Charge -3

This species takes part in two reactions (as a reactant in R CITabc, R EX cit e).

d M cit e = −v − v (2258) dt 148 270

7.209 Species M citr DASH L c

Name L-Citrulline

Charge 0

This species takes part in three reactions (as a reactant in R ARGSS and as a product in R ARGDr, R OCBT).

d M citr DASH L c = v + v − v (2259) dt 99 721 101

7.210 Species M cl c

Name Chloride

Charge -1

This species takes part in one reaction (as a product in R Clt).

d M cl c = v (2260) dt 187

7.211 Species M cl e

Name Chloride

Charge -1

This species takes part in two reactions (as a reactant in R Clt, R EX cl e).

d M cl e = −v − v (2261) dt 187 271

Produced by SBML2LATEX 913 7.212 Species M clpn160190 c Name cardiolipin (dihexadecanoyl, dimethylstearoyl)

Charge -2

This species takes part in two reactions (as a reactant in R biomass Mtb 9 60atp and as a product in R CLPNS160190). d M clpn160190 c = v − 0.005859v (2262) dt 149 1025

7.213 Species M cmcbtt c Name carboxymycobactin T (R=8 carbon, ﬁnal carbon is carboxyl group)

Charge 1

This species takes part in three reactions (as a reactant in R CMCBTFL and as a product in R- CMCBTFU, R MCBTS3). d M cmcbtt c = v + v − v (2263) dt 151 595 150

7.214 Species M cmp c Name CMP

Charge -2

This species takes part in 17 reactions (as a reactant in R CYTK1, R NTD4, R biomass Mtb- 9 60atp and as a product in R CDAPPA160, R CDAPPA160190, R CDAPPA190, R CDPPT160, R CDPPT160190, R CYTDK2, R MECDPS, R NTPP4, R PGSA160, R PGSA160190, R PGSA190, R- PPNCL2, R PSSA160, R PSSA180).

d M cmp c = v + v + v + v + v + v + v + v + v dt 134 135 136 138 139 183 602 710 783 (2264) + v784 + v785 + v822 + v853 + v854 − v185 − v702 − 0.250951v1025

7.215 Species M co1dam c Name Cob(I)yrinate a,c diamide

Charge -5

This species takes part in two reactions (as a reactant in R CYRDAAT and as a product in R- CYRDAR). d M co1dam c = 2v − v (2265) dt 175 174

914 Produced by SBML2LATEX 7.216 Species M co2 c

Name CO2

Charge 0

This species takes part in 109 reactions (as a reactant in R ACCC, R AIRCr, R DBTSr, R H2CO3D, R HCO3E and as a product in R ACHBS, R ACLS, R ADMDCr, R AOXSr, R ARGDC, R ASP1DC, R- CMLDC, R CO2t, R CODH2r, R CODH3, R CPC6MT, R CPPPGO, R DAPDC, R DHNAOT, R DHNAOT2, R DXPS, R FAS100, R FAS120, R FAS140, R FAS160, R FAS161, R FAS180, R FAS181, R- FAS200, R FAS240 L, R FAS260, R FAS80 L, R FASPHDCA, R FASm1601, R FASm180, R FASm1801, R FASm2001, R FASm2002, R FASm220, R FASm2201, R FASm2202, R FASm240, R FASm2401, R FASm2402, R FASm260, R FASm2601, R FASm2602, R FASm280, R FASm2801, R FASm2802, R FASm300, R FASm3001, R FASm320, R FASm340, R FDH, R FHL, R GCCa, R GLUDC, R GLYCL, R GND, R ICDHy, R IGPS, R INDPYRD, R LO, R MCBTS, R MCBTS2, R MCBTS3, R MCD, R ME1, R MMCD, R MMSAD1, R MMSAD3, R MYCON1, R MYCON2, R MYCON3, R MYCON4, R MYCON5, R- MYCSacp50, R MYCSacp56, R MYCSacp58, R NNDPR, R OMCDC, R OMPDC, R OXCDC, R OXGDC, R OXGDC2, R PC6YM, R PDH, R PDHa, R PEPCK re, R PHTHDLS, R PHTHDLS2, R PHYCBOXL, R- PNCDC, R PPCDC, R PPCKr, R PPND, R PPNDH, R PREPTHS, R PREPTHS2, R PSD160, R PSD180, R PYRDC, R SADH, R THZPSN, R THZSN, R UPPDC1, R UPPDC2, R UREA).

d M co2 c = v + v + v + v + v + v + v + v + v + 2v + v + 2v + v dt 20 22 41 88 98 108 152 153 157 158 163 166 195 + v223 + v224 + v251 + v366 + v367 + v368 + v369 + v370 + v371 + v372 + v373 + 3v374 +v375 +3v376 +8v377 +v378 +5v379 +v380 +v381 +v382 +v383 +v384 +v385 +v386 + v387 + v388 + v389 + v390 + v391 + v392 + v393 + v394 + v395 + v396 + v397 + v398 + v405 + v410 + v457 + v475 + v486 + v498 + v543 + v550 + v555 + v573 + v593 + v594 +v595 +v596 +v600 +v618 +v621 +v623 +v655 +v656 +v657 +v658 +v659 +12v660 +15v661 +16v662 +v690 +v726 +v727 +v734 +v735 +v736 +v753 +v757 +v758 +v766 +v793 +v794 +v798 +v807 +v812 +v813 +v824 +v825 +2v839 +2v840 +v849 +v850 +v868 +v892 +v950 +v951 +4v1012 +4v1013 +v1015 −v13 −v68 −v201 −v514 −v520 (2266)

7.217 Species M co2 e

Name CO2

Charge 0

This species takes part in two reactions (as a reactant in R CO2t, R EX co2 e).

d M co2 e = −v − v (2267) dt 153 272

Produced by SBML2LATEX 915 7.218 Species M co2dam c Name Cob(II)yrinate a,c diamide

Charge -4

This species takes part in two reactions (as a reactant in R CYRDAR and as a product in R COCHL). d M co2dam c = v − 2v (2268) dt 156 175

7.219 Species M co c Name Carbon monoxide

Charge 0

This species takes part in three reactions (as a reactant in R CODH2r, R CODH3, R COt). d M co c = −v − 2v − v (2269) dt 157 158 159

7.220 Species M co e Name Carbon monoxide

Charge 0

This species takes part in two reactions (as a reactant in R EX co e and as a product in R COt). d M co e = v − v (2270) dt 159 273

7.221 Species M coa c Name Coenzyme A

Charge -4

This species takes part in 100 reactions (as a reactant in R ACALDi, R ACChex, R ACPS1, R ACS, R ACS2, R AKGDb, R FACOAL140, R FACOAL160, R FACOAL161, R FACOAL180, R FACOAL181, R FACOAL200, R FACOAL80, R FACOALPHDCA, R FACOALPREPH, R FAO1, R FAO10, R FAO11, R FAO2, R FAO3, R FORMCOAL, R MMSAD1, R MMSAD2, R MMSAD3, R OXACOAL, R PDH, R PDHbr, R PFL, R SUCBZL, R SUCOAS and as a product in R ACACT1r, R ACGS, R AOXSr, R ARACHTA, R AST, R COAt, R CS, R DPCOAK, R FACOAE140, R FACOAE160, R FACOAE180, R FAS100, R- FAS120, R FAS140, R FAS160, R FAS161, R FAS180, R FAS181, R FAS200, R FAS240 L, R- FAS260, R FAS80 L, R FASm1601, R FASm180, R FASm1801, R FASm2001, R FASm2002, R- FASm220, R FASm2201, R FASm2202, R FASm240, R FASm2401, R FASm2402, R FASm260, R- FASm2601, R FASm2602, R FASm280, R FASm2801, R FASm2802, R FASm300, R FASm3001,

916 Produced by SBML2LATEX R FASm320, R FASm340, R FCOAH2, R G1PACT, R HSERTA, R HSST, R IPPS, R MALS, R MANAT1, R MANAT2, R MANAT3, R MCBTS, R MCBTS2, R MCBTS3, R MCOATA, R MSHS, R MYCON1, R MYCON2, R MYCON3, R MYCON4, R MYCON5, R NPHS, R PHDCATA, R PREPTHS, R PREPTHS2, R PREPTTA, R PTAr, R SERAT, R THDPS). d M coa c = v +v +v +v +v +v +v +v +v +v +v +v +v +v dt 10 19 88 93 115 154 168 241 343 344 345 366 367 368 +v369 +v370 +v371 +v372 +v373 +3v374 +v375 +4v376 +v378 +5v379 +v380 +v381 + v382 + v383 + v384 + v385 + v386 + v387 + v388 + v389 + v390 + v391 + v392 + v393 + v394 + v395 + v396 + v397 + v398 + v404 + v439 + v537 + v539 + v563 + v582 + v590 +v591 +v592 +v593 +v594 +v595 +v597 +v633 +v655 +v656 +v657 +v658 +v659 +v696 +v786 +4v839 +4v840 +v841 +v855 +v899 +v943 −v11 −v15 −v27 −v28 −v29 −v69 −v346 −v347 −v348 −v349 −v350 −v351 −v352 −v353 −v354 −7v361 −9v362 −8v363 − 8v364 − 9v365 − v416 − v621 − v622 − v623 − v733 − v757 − v759 − v769 − v922 − v926 (2271)

7.222 Species M coa e Name Coenzyme A

Charge -4

This species takes part in two reactions (as a reactant in R COAt, R EX coa e). d M coa e = −v − v (2272) dt 154 274

7.223 Species M cobalt2 c Name Co2+

Charge 2

This species takes part in two reactions (as a reactant in R COBALTt5, R COCHL). d M cobalt2 c = −v − v (2273) dt 155 156

7.224 Species M cobalt2 e Name Co2+

Charge 2

This species takes part in two reactions (as a reactant in R EX cobalt2 e and as a product in R COBALTt5). d M cobalt2 e = v − v (2274) dt 155 275

Produced by SBML2LATEX 917 7.225 Species M cobya c Name Cobyrinate

Charge -6 This species takes part in one reaction (as a product in R CPC8MM). d M cobya c = v (2275) dt 165

7.226 Species M codhpre6 c Name cobalt-dihydro-precorrin 6

Charge -7 This species takes part in two reactions (as a reactant in R CPC6MT and as a product in R CPC6R). d M codhpre6 c = v − v (2276) dt 164 163

7.227 Species M copre2 c Name cobalt-precorrin 2

Charge -8 This species takes part in one reaction (as a reactant in R CPC2MT). d M copre2 c = −v (2277) dt 160

7.228 Species M copre3 c Name cobalt-precorrin 3

Charge -8 This species takes part in two reactions (as a reactant in R CPC3MT and as a product in R CPC2MT). d M copre3 c = v − v (2278) dt 160 161

7.229 Species M copre4 c Name cobalt-precorrin 4

Charge -7 This species takes part in two reactions (as a reactant in R CPC4MT and as a product in R CPC3MT). d M copre4 c = v − v (2279) dt 161 162

918 Produced by SBML2LATEX 7.230 Species M copre5 c Name cobalt-precorrin 5

Charge -7 This species takes part in one reaction (as a product in R CPC4MT). d M copre5 c = v (2280) dt 162

7.231 Species M copre6 c Name cobalt-precorrin 6

Charge -7 This species takes part in one reaction (as a reactant in R CPC6R). d M copre6 c = −v (2281) dt 164

7.232 Species M copre8 c Name cobalt-precorrin 8

Charge -6 This species takes part in two reactions (as a reactant in R CPC8MM and as a product in R CPC6MT). d M copre8 c = v − v (2282) dt 163 165

7.233 Species M cpppg1 c Name Coproporphyrinogen I

Charge -4 This species takes part in one reaction (as a product in R UPPDC2). d M cpppg1 c = v (2283) dt 1013

7.234 Species M cpppg3 c Name Coproporphyrinogen III

Charge -4 This species takes part in two reactions (as a reactant in R CPPPGO and as a product in R UPPDC1). d M cpppg3 c = v − v (2284) dt 1012 166

Produced by SBML2LATEX 919 7.235 Species M crn c

Name L-Carnitine

Charge 0

This species takes part in one reaction (as a product in R CRNabc).

d M crn c = v (2285) dt 167

7.236 Species M crn e

Name L-Carnitine

Charge 0

This species takes part in two reactions (as a reactant in R CRNabc, R EX crn e).

d M crn e = −v − v (2286) dt 167 276

7.237 Species M ctp c

Name CTP

Charge -4

This species takes part in twelve reactions (as a reactant in R DASYN160, R DASYN160190, R- DASYN190190, R DCTPD2, R HMPK2, R MEPCT, R NTPP4, R PPNCL, R PPNCL2 and as a product in R CTPS1, R CTPS2, R NDPK3).

d M ctp c = v + v + v − v − v − v − v − v − v − v − v − v dt 169 170 678 197 198 199 210 529 604 710 821 822 (2287)

7.238 Species M cu2 c

Name Cu2+

Charge 2

This species takes part in two reactions (as a reactant in R Cut1 and as a product in R Cuabc).

d M cu2 c = v − v (2288) dt 188 189

920 Produced by SBML2LATEX 7.239 Species M cu2 e

Name Cu2+

Charge 2

This species takes part in three reactions (as a reactant in R Cuabc, R EX cu2 e and as a product in R Cut1). d M cu2 e = v − v − v (2289) dt 189 188 277

7.240 Species M cyan c

Name Hydrogen cyanide

Charge 0

This species takes part in two reactions (as a reactant in R CYANST, R THSFST). d M cyan c = −v − v (2290) dt 171 949

7.241 Species M cys DASH L c

Name L-Cysteine

Charge 0

This species takes part in 13 reactions (as a reactant in R BTS2, R CIGAMS, R GLUCYS, R PPNCL, R PPNCL2, R PPNCL3, R SHSL1r, R THZPSN, R THZSN, R biomass Mtb 9 60atp and as a product in R AMPTASECG, R CYSS, R CYSTGL).

d M cys DASH L c = v + v + v − v − v − v − v dt 85 176 177 126 145 474 821 (2291) − v822 − v823 − v914 − v950 − v951 − 0.022v1025

7.242 Species M cyst DASH L c

Name L-Cystathionine

Charge 0

This species takes part in four reactions (as a reactant in R CYSTGL, R CYSTL and as a product in R CYSTS, R SHSL1r). d M cyst DASH L c = v + v − v − v (2292) dt 179 914 177 178

Produced by SBML2LATEX 921 7.243 Species M cytd c

Name Cytidine

Charge 0

This species takes part in four reactions (as a reactant in R CYTD, R CYTDK2 and as a product in R CYTDt2r, R NTD4).

d M cytd c = v + v − v − v (2293) dt 184 702 182 183

7.244 Species M cytd e

Name Cytidine

Charge 0

This species takes part in two reactions (as a reactant in R CYTDt2r, R EX cytd e).

d M cytd e = −v − v (2294) dt 184 278

7.245 Species M dad DASH 2 c

Name Deoxyadenosine

Charge 0

This species takes part in three reactions (as a reactant in R DADA, R PUNP2 and as a product in R NTD6).

d M dad DASH 2 c = v − v − v (2295) dt 704 190 858

7.246 Species M dadp c

Name dADP

Charge -3

This species takes part in three reactions (as a reactant in R NDPK8 and as a product in R DADK, R RNDR1).

d M dadp c = v + v − v (2296) dt 191 882 683

922 Produced by SBML2LATEX 7.247 Species M damp c Name dAMP

Charge -2 This species takes part in four reactions (as a reactant in R DADK, R NTD6, R biomass Mtb 9- 60atp and as a product in R NTPP5). d M damp c = v − v − v − 0.003492v (2297) dt 711 191 704 1025

7.248 Species M dann c Name 7,8-Diaminononanoate

Charge 1 This species takes part in two reactions (as a reactant in R DBTSr and as a product in R AMAOTr). d M dann c = v − v (2298) dt 80 201

7.249 Species M datp c Name dATP

Charge -4 This species takes part in two reactions (as a reactant in R NTPP5 and as a product in R NDPK8). d M datp c = v − v (2299) dt 683 711

7.250 Species M db4p c Name 3,4-dihydroxy-2-butanone 4-phosphate

Charge -2 This species takes part in two reactions (as a reactant in R RBFSa and as a product in R DB4PS). d M db4p c = v − v (2300) dt 200 876

7.251 Species M dca c Name Decanoate (n-C10:0)

Charge -1 This species takes part in two reactions (as a reactant in R FAS120 and as a product in R FAS100). d M dca c = v − v (2301) dt 366 367

Produced by SBML2LATEX 923 7.252 Species M dcamp c

Name N6-(1,2-Dicarboxyethyl)-AMP

Charge -4

This species takes part in two reactions (as a reactant in R ADSL1r and as a product in R ADSS).

d M dcamp c = v − v (2302) dt 52 50

7.253 Species M dcdp c

Name dCDP

Charge -3

This species takes part in three reactions (as a reactant in R NDPK7 and as a product in R CYTK2, R RNDR3).

d M dcdp c = v + v − v (2303) dt 186 884 682

7.254 Species M dcmp c

Name dCMP

Charge -2

This species takes part in four reactions (as a reactant in R CYTK2, R NTD3, R biomass Mtb 9- 60atp and as a product in R NTPP3).

d M dcmp c = v − v − v − 0.006663v (2304) dt 709 186 701 1025

7.255 Species M dctp c

Name dCTP

Charge -4

This species takes part in three reactions (as a reactant in R DCTPD, R NTPP3 and as a product in R NDPK7).

d M dctp c = v − v − v (2305) dt 682 209 709

924 Produced by SBML2LATEX 7.256 Species M dcyt c

Name Deoxycytidine

Charge 0

This species takes part in two reactions (as a reactant in R DCYTD and as a product in R NTD3).

d M dcyt c = v − v (2306) dt 701 211

7.257 Species M ddca c

Name Dodecanoate (n-C12:0)

Charge -1

This species takes part in two reactions (as a reactant in R FAS140 and as a product in R FAS120).

d M ddca c = v − v (2307) dt 367 368

7.258 Species M decd tb c

Name (E,E,E,E,E,E,E,Z,Z) decaprenyl phosphate

Charge -2

This species takes part in nine reactions (as a reactant in R DCPT, R DCPT2, R GMT1 and as a product in R AFTA, R DCPDP, R G16MTM4, R G16MTM5, R HAS, R TAS).

d M decd tb c = v + v + v + v + 5v + 3v − v − v − v (2308) dt 54 202 433 434 519 932 207 208 496

7.259 Species M decda tb c

Name decaprenylphosphoryl-beta-D-arabinofuranose

Charge -2

This species takes part in ﬁve reactions (as a reactant in R AFTA, R HAS, R TAS and as a product in R DCPDPP2, R DCPE).

d M decda tb c = v + v − v − 5v − 3v (2309) dt 204 206 54 519 932

Produced by SBML2LATEX 925 7.260 Species M decdman1p tb c

Name (E,E,E,E,E,E,E,Z,Z) decaprenyl mannose phosphate

Charge -1

This species takes part in three reactions (as a reactant in R G16MTM4, R G16MTM5 and as a product in R GMT1).

d M decdman1p tb c = v − v − v (2310) dt 496 433 434

7.261 Species M decdp c

Name all trans Decaprenyl diphosphate

Charge -3

This species takes part in two reactions (as a reactant in R UDPDPS and as a product in R DPPS).

d M decdp c = v − v (2311) dt 242 996

7.262 Species M decdp tb c

Name (E,E,E,E,E,E,E,Z,Z) Decaprenyl diphosphate

Charge -3

This species takes part in three reactions (as a reactant in R DCPDP, R UDPDPS2 and as a product in R DCPDPS).

d M decdp tb c = v − v − v (2312) dt 205 202 997

7.263 Species M decdpa tb c

Name decaprenylphosphoryl-beta-D-5-phosphoarabinofuranose

Charge -4

This species takes part in two reactions (as a reactant in R DCPDPP2 and as a product in R DCPT2).

d M decdpa tb c = v − v (2313) dt 208 204

926 Produced by SBML2LATEX 7.264 Species M decdpr tb c

Name decaprenylphosphoryl-beta-D-5-phosphoribose

Charge -4

This species takes part in two reactions (as a reactant in R DCPDPP and as a product in R DCPT).

d M decdpr tb c = v − v (2314) dt 207 203

7.265 Species M decdr tb c

Name decaprenylphosphoryl-beta-D-5-ribose

Charge -2

This species takes part in two reactions (as a reactant in R DCPE and as a product in R DCPDPP).

d M decdr tb c = v − v (2315) dt 203 206

7.266 Species M dgdp c

Name dGDP

Charge -3

This species takes part in four reactions (as a reactant in R NDPK5 and as a product in R ADNK4, R DGK1, R RNDR2).

d M dgdp c = v + v + v − v (2316) dt 45 216 883 680

7.267 Species M dgmp c

Name dGMP

Charge -2

This species takes part in three reactions (as a reactant in R DGK1, R NTD8, R biomass Mtb 9- 60atp).

d M dgmp c = −v − v − 0.006659v (2317) dt 216 706 1025

Produced by SBML2LATEX 927 7.268 Species M dgsn c

Name Deoxyguanosine

Charge 0

This species takes part in three reactions (as a reactant in R PUNP4 and as a product in R NTD8, R NTPTP1).

d M dgsn c = v + v − v (2318) dt 706 714 860

7.269 Species M dgtp c

Name dGTP

Charge -4

This species takes part in three reactions (as a reactant in R ADNK4, R NTPTP1 and as a product in R NDPK5).

d M dgtp c = v − v − v (2319) dt 680 45 714

7.270 Species M dhap c

Name Dihydroxyacetone phosphate

Charge -2

This species takes part in ﬁve reactions (as a reactant in R QULNS, R TPI and as a product in R FBA, R FCLPA, R G3PD1).

d M dhap c = v + v + v − v − v (2320) dt 399 401 444 871 966

7.271 Species M dhf c

Name 7,8-Dihydrofolate

Charge -2

This species takes part in four reactions (as a reactant in R DHFR and as a product in R DHFS, R FOLR2, R TMDS).

d M dhf c = v + v + v − v (2321) dt 222 414 956 221

928 Produced by SBML2LATEX 7.272 Species M dhlam c

Name Dihydrolipoamide

Charge 0

This species takes part in ﬁve reactions (as a reactant in R PDHc, R PDHcr and as a product in R AKGDb, R GCC2, R PDHbr).

d M dhlam c = v + v + v − v − v (2322) dt 69 456 759 760 761

7.273 Species M dhlpro c

Name Dihydrolipolprotein

Charge 0

This species takes part in two reactions (as a reactant in R GCCc and as a product in R GCCb).

d M dhlpro c = v − v (2323) dt 458 459

7.274 Species M dhna c

Name 1,4-Dihydroxy-2-naphthoate

Charge -1

This species takes part in ﬁve reactions (as a reactant in R DHNAOT, R DHNAOT2, R MNDNS1, R- MNDNS2 and as a product in R NPHS).

d M dhna c = v − v − v − v − v (2324) dt 696 223 224 625 626

7.275 Species M dhnpt c

Name Dihydroneopterin

Charge 0

This species takes part in three reactions (as a reactant in R DHNPA, R DHNPA2 and as a product in R DNMPPA).

d M dhnpt c = v − v − v (2325) dt 239 225 226

Produced by SBML2LATEX 929 7.276 Species M dhor DASH S c

Name (S)-Dihydroorotate

Charge -1

This species takes part in four reactions (as a reactant in R DHORD2, R DHORD3, R DHORD5, R- DHORTS).

d M dhor DASH S c = −v − v − v − v (2326) dt 227 228 229 230

7.277 Species M dhpmp c

Name Dihydroneopterin monophosphate

Charge -2

This species takes part in two reactions (as a reactant in R DNMPPA and as a product in R DNTPPA).

d M dhpmp c = v − v (2327) dt 240 239

7.278 Species M dhpt c

Name Dihydropteroate

Charge -1

This species takes part in three reactions (as a reactant in R DHFS and as a product in R DHPS2, R FOLD3).

d M dhpt c = v + v − v (2328) dt 233 413 222

7.279 Species M din c

Name Deoxyinosine

Charge 0

This species takes part in two reactions (as a reactant in R PUNP6 and as a product in R DADA).

d M din c = v − v (2329) dt 190 862

930 Produced by SBML2LATEX 7.280 Species M dmarach c

Name di-methyl arachic acid

Charge -1

This species takes part in two reactions (as a reactant in R FASm2001 and as a product in R- FASm1801).

d M dmarach c = v − v (2330) dt 380 381

7.281 Species M dmbhn c

Name di-methyl behenic acid

Charge -1

This species takes part in two reactions (as a reactant in R FASm2402 and as a product in R- FASm2202).

d M dmbhn c = v − v (2331) dt 385 388

7.282 Species M dmbzid c

Name 5,6-Dimethylbenzimidazole

Charge 0

This species takes part in one reaction (as a reactant in R NNDMBRT).

d M dmbzid c = −v (2332) dt 689

7.283 Species M dmlgnc c

Name dimethyl lignoceric acid

Charge -1

This species takes part in two reactions (as a reactant in R FASm260 and as a product in R- FASm240).

d M dmlgnc c = v − v (2333) dt 386 389

Produced by SBML2LATEX 931 7.284 Species M dmlz c

Name 6,7-Dimethyl-8-(1-D-ribityl)lumazine

Charge 0

This species takes part in two reactions (as a reactant in R RBFSb and as a product in R RBFSa).

d M dmlz c = v − 2v (2334) dt 876 877

7.285 Species M dmpp c

Name Dimethylallyl diphosphate

Charge -3

This species takes part in three reactions (as a reactant in R DMATT and as a product in R DMPPS, R IPDDI).

d M dmpp c = v + v − v (2335) dt 237 558 236

7.286 Species M dnad c

Name Deamino-NAD+

Charge -2

This species takes part in two reactions (as a reactant in R NADS2 and as a product in R NNAT).

d M dnad c = v − v (2336) dt 688 670

7.287 Species M dpcoa c

Name Dephospho-CoA

Charge -2

This species takes part in two reactions (as a reactant in R DPCOAK and as a product in R PTPATi).

d M dpcoa c = v − v (2337) dt 856 241

932 Produced by SBML2LATEX 7.288 Species M dscl c

Name dihydrosirohydrochlorin

Charge -7

This species takes part in three reactions (as a reactant in R PC20M, R SHCHD2 and as a product in R UPP3MT).

d M dscl c = v − v − v (2338) dt 1010 751 907

7.289 Species M dtbt c

Name Dethiobiotin

Charge -1

This species takes part in three reactions (as a reactant in R BTS2, R BTS3r and as a product in R DBTSr).

d M dtbt c = v − v − v (2339) dt 201 126 127

7.290 Species M dtdp4d6dg c

Name dTDP-4-dehydro-6-deoxy-D-glucose

Charge -2

This species takes part in two reactions (as a reactant in R TDPDRE and as a product in R TDPGDH).

d M dtdp4d6dg c = v − v (2340) dt 941 939

7.291 Species M dtdp4d6dm c

Name dTDP-4-dehydro-6-deoxy-L-mannose

Charge -2

This species takes part in two reactions (as a reactant in R TDPDRR and as a product in R TDPDRE).

d M dtdp4d6dm c = v − v (2341) dt 939 940

Produced by SBML2LATEX 933 7.292 Species M dtdp c

Name dTDP

Charge -3

This species takes part in ﬁve reactions (as a reactant in R NDPK4 and as a product in R DTMPK, R O16RHAT, R RPPDIMAS, R RRPPDIMAS).

d M dtdp c = v + v + v + v − v (2342) dt 246 719 889 890 679

7.293 Species M dtdpglu c

Name dTDPglucose

Charge -2

This species takes part in two reactions (as a reactant in R TDPGDH and as a product in R G1PTT).

d M dtdpglu c = v − v (2343) dt 440 941

7.294 Species M dtdprmn c

Name dTDP-L-rhamnose

Charge -2

This species takes part in four reactions (as a reactant in R O16RHAT, R RPPDIMAS, R RRPPDIMAS and as a product in R TDPDRR).

d M dtdprmn c = v − v − v − v (2344) dt 940 719 889 890

7.295 Species M dtmp c

Name dTMP

Charge -2

This species takes part in six reactions (as a reactant in R DTMPK, R NTD5, R biomass Mtb 9- 60atp and as a product in R NTPP7, R TMDK1, R TMDS).

d M dtmp c = v + v + v − v − v − 0.003653v (2345) dt 712 954 956 246 703 1025

934 Produced by SBML2LATEX 7.296 Species M dttOX c

Name Oxidized dithiothreitol

Charge 0

This species takes part in one reaction (as a product in R SELCYSLY).

d M dttOX c = v (2346) dt 898

7.297 Species M dtt c

Name Dithiothreitol

Charge 0

This species takes part in one reaction (as a reactant in R SELCYSLY).

d M dtt c = −v (2347) dt 898

7.298 Species M dttp c

Name dTTP

Charge -4

This species takes part in three reactions (as a reactant in R G1PTT, R NTPP7 and as a product in R NDPK4).

d M dttp c = v − v − v (2348) dt 679 440 712

7.299 Species M dudp c

Name dUDP

Charge -3

This species takes part in three reactions (as a reactant in R NDPK6 and as a product in R RNDR4, R URIDK2r).

d M dudp c = v + v − v (2349) dt 885 1017 681

Produced by SBML2LATEX 935 7.300 Species M dump c

Name dUMP

Charge -2

This species takes part in ﬁve reactions (as a reactant in R NTD1, R TMDS, R URIDK2r and as a product in R DURIK1, R DUTPDP).

d M dump c = v + v − v − v − v (2350) dt 247 249 697 956 1017

7.301 Species M duri c

Name Deoxyuridine

Charge 0

This species takes part in four reactions (as a reactant in R DURIK1, R DURIPP and as a product in R DCYTD, R NTD1).

d M duri c = v + v − v − v (2351) dt 211 697 247 248

7.302 Species M dutp c

Name dUTP

Charge -4

This species takes part in four reactions (as a reactant in R DUTPDP and as a product in R DCTPD, R NDPK6, R RNTR4).

d M dutp c = v + v + v − v (2352) dt 209 681 886 249

7.303 Species M dxyl5p c

Name 1-deoxy-D-xylulose 5-phosphate

Charge -2

This species takes part in three reactions (as a reactant in R DXPRIi, R THZPSN and as a product in R DXPS).

d M dxyl5p c = v − v − v (2353) dt 251 250 950

936 Produced by SBML2LATEX 7.304 Species M dxyl c Name 1-deoxy-D-xylulose

Charge 0 This species takes part in one reaction (as a reactant in R THZSN). d M dxyl c = −v (2354) dt 951

7.305 Species M e4p c Name D-Erythrose 4-phosphate

Charge -2 This species takes part in four reactions (as a reactant in R DDPA, R E4PD, R TKT2 and as a product in R TALA). d M e4p c = v − v − v − v (2355) dt 929 212 252 953

7.306 Species M eig3p c Name D-erythro-1-(Imidazol-4-yl)glycerol 3-phosphate

Charge -2 This species takes part in two reactions (as a reactant in R IGPDH and as a product in R IG3PS). d M eig3p c = v − v (2356) dt 547 549

7.307 Species M enter c Name Enterochelin

Charge 0 This species takes part in one reaction (as a product in R ENTCS). d M enter c = v (2357) dt 255

7.308 Species M etha c Name Ethanolamine

Charge 1 This species takes part in two reactions (as a product in R ETHAt, R GPDDA2). d M etha c = v + v (2358) dt 256 499

Produced by SBML2LATEX 937 7.309 Species M etha e

Name Ethanolamine

Charge 1

This species takes part in two reactions (as a reactant in R ETHAt, R EX etha e).

d M etha e = −v − v (2359) dt 256 279

7.310 Species M f6p c

Name D-Fructose 6-phosphate

Charge -2

This species takes part in seven reactions (as a reactant in R GF6PTAr, R PFK and as a product in R FBP, R MAN6PI, R PGI, R TALA, R TKT2).

d M f6p c = v + v + v + v + v − v − v (2360) dt 400 589 772 929 953 460 768

7.311 Species M fad c

Name Flavin adenine dinucleotide oxidized

Charge -2

This species takes part in ten reactions (as a reactant in R FAO1, R FAO10, R FAO11, R FAO2, R FAO3, R PROD2, R SUCD1i and as a product in R FE3Ri, R FMNAT, R FRD).

d M fad c = v + v + v − 6v − 7v − 6v − 7v − 8v − v − v (2361) dt 407 412 417 361 362 363 364 365 844 925

7.312 Species M fadh2 c

Name Flavin adenine dinucleotide reduced

Charge -2

This species takes part in nine reactions (as a reactant in R FE3Ri, R FRD and as a product in R FAO1, R FAO10, R FAO11, R FAO2, R FAO3, R PROD2, R SUCD1i).

d M fadh2 c = 6v + 7v + 6v + 7v + 8v + v + v − v − v (2362) dt 361 362 363 364 365 844 925 407 417

938 Produced by SBML2LATEX 7.313 Species M fald c

Name Formaldehyde

Charge 0

This species takes part in two reactions (as a reactant in R ALDD1 and as a product in R PRDX).

d M fald c = v − v (2363) dt 836 77

7.314 Species M fc1p c

Name L-Fuculose 1-phosphate

Charge -2

This species takes part in one reaction (as a reactant in R FCLPA).

d M fc1p c = −v (2364) dt 401

7.315 Species M fcmcbtt c

Name iron(III) chelated carboxymycobactin T (R=8 carbon, ﬁnal carbon is carboxyl group)

Charge 4

This species takes part in three reactions (as a reactant in R CMCBTFU, R biomass Mtb 9 60atp and as a product in R CMCBTFL).

d M fcmcbtt c = v − v − 0.001498v (2365) dt 150 151 1025

7.316 Species M fdox c

Name ferredoxin (oxidized) 2[4Fe-4S]

Charge 3

This species takes part in two reactions (as a reactant in R CODH2r, R ECHH 0).

d M fdox c = −2v − 2v (2366) dt 157 253

Produced by SBML2LATEX 939 7.317 Species M fdp c

Name D-Fructose 1,6-bisphosphate

Charge -4

This species takes part in three reactions (as a reactant in R FBA, R FBP and as a product in R PFK).

d M fdp c = v − v − v (2367) dt 768 399 400

7.318 Species M fdred c

Name ferredoxin (reduced) 2[4Fe-4S]

Charge 2

This species takes part in two reactions (as a product in R CODH2r, R ECHH 0).

d M fdred c = 2v + 2v (2368) dt 157 253

7.319 Species M fdxox c

Name Oxidized ferredoxin

Charge 0

This species takes part in one reaction (as a product in R FRDOr).

d M fdxox c = v (2369) dt 423

7.320 Species M fdxrd c

Name Reduced ferredoxin

Charge 0

This species takes part in one reaction (as a reactant in R FRDOr).

d M fdxrd c = −v (2370) dt 423

940 Produced by SBML2LATEX 7.321 Species M fe2 c

Name Fe2+

Charge 2

This species takes part in six reactions (as a reactant in R FCLT, R SHCHF, R SHCHF2 and as a product in R FE2abc, R FE3Ri, R FETRANS).

d M fe2 c = v + 2v + v − v − v − v (2371) dt 406 407 409 402 909 910

7.322 Species M fe2 e

Name Fe2+

Charge 2

This species takes part in two reactions (as a reactant in R EX fe2 e, R FE2abc).

d M fe2 e = −v − v (2372) dt 280 406

7.323 Species M fe3 c

Name Fe3+

Charge 3

This species takes part in three reactions (as a reactant in R FE3Ri and as a product in R- CMCBTFU, R FE3abc).

d M fe3 c = v + v − 2v (2373) dt 151 408 407

7.324 Species M fe3 e

Name Fe3+

Charge 3

This species takes part in three reactions (as a reactant in R CMCBTFL, R EX fe3 e, R FE3abc).

d M fe3 e = −v − v − v (2374) dt 150 281 408

Produced by SBML2LATEX 941 7.325 Species M fgam c

Name N2-Formyl-N1-(5-phospho-D-ribosyl)glycinamide

Charge -2

This species takes part in two reactions (as a reactant in R PRFGS and as a product in R GARFT).

d M fgam c = v − v (2375) dt 455 842

7.326 Species M ficytc c

Name Ferricytochrome c

Charge 1

This species takes part in three reactions (as a reactant in R CYO1a, R L LACD and as a product in R CYO1b).

d M ﬁcytc c = 2v − 2v − 2v (2376) dt 173 172 577

7.327 Species M fmcbtt c

Name Iron(II) mycobactin T

Charge 4

This species takes part in three reactions (as a reactant in R FCLT2, R FETRANS, R SHCHF3).

d M fmcbtt c = −v − v − v (2377) dt 403 409 911

7.328 Species M fmettrna c

Name N-Formylmethionyl-tRNA

Charge 0

This species takes part in one reaction (as a product in R FMETTRS).

d M fmettrna c = v (2378) dt 411

942 Produced by SBML2LATEX 7.329 Species M fmn c

Name FMN

Charge -2

This species takes part in three reactions (as a reactant in R ACP1 FMN, R FMNAT and as a product in R RBFK). d M fmn c = v − v − v (2379) dt 875 26 412

7.330 Species M focytc c

Name Ferrocytochrome c

Charge 1

This species takes part in three reactions (as a reactant in R CYO1b and as a product in R CYO1a, R L LACD). d M focytc c = 2v + 2v − 2v (2380) dt 172 577 173

7.331 Species M fol c

Name Folate

Charge -1

This species takes part in one reaction (as a reactant in R FOLR2). d M fol c = −v (2381) dt 414

7.332 Species M for c

Name Formate

Charge -1

This species takes part in 14 reactions (as a reactant in R AICART2, R FDH, R FHL, R FORMCOAL, R FTHFL and as a product in R ALDD1, R DB4PS, R FCOAH2, R FTHFD, R GTPCI, R GTPCII, R- GTPCII2, R MSHOXH, R PFL).

d M for c = v + v + v + v + v + v + v dt 77 200 404 426 506 507 508 (2382) + v632 + v769 − v65 − v405 − v410 − v416 − v427

Produced by SBML2LATEX 943 7.333 Species M forcoa c

Name Formyl-CoA

Charge -4

This species takes part in three reactions (as a reactant in R FCOAH2 and as a product in R- FORMCOAL, R OXCDC).

d M forcoa c = v + v − v (2383) dt 416 734 404

7.334 Species M fpram c

Name 2-(Formamido)-N1-(5-phospho-D-ribosyl)acetamidine

Charge -1

This species takes part in two reactions (as a reactant in R PRAIS and as a product in R PRFGS).

d M fpram c = v − v (2384) dt 842 831

7.335 Species M fprica c

Name 5-Formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

Charge -2

This species takes part in three reactions (as a product in R AICART, R AICART2, R IMPC).

d M fprica c = v + v + v (2385) dt 64 65 553

7.336 Species M frdp c

Name Farnesyl diphosphate

Charge -3

This species takes part in ﬁve reactions (as a reactant in R DCPDPS, R DPPS, R OCTDPS, R- UDCPDPS and as a product in R GRTT).

d M frdp c = v − v − v − v − v (2386) dt 500 205 242 724 995

944 Produced by SBML2LATEX 7.337 Species M frrppdima c

Name fucose rhamnose rhamnose phenol phthiocerol dimycocerosate (Mtb)

Charge 0

This species takes part in two reactions (as a reactant in R PGLS and as a product in R FRRPPDIMAS).

d M frrppdima c = v − v (2387) dt 424 775

7.338 Species M fum c

Name Fumarate

Charge -2

This species takes part in eleven reactions (as a reactant in R ASPO5, R FRD, R FRD2, R FRD3, R FRD5, R FUM and as a product in R ADSL1r, R ADSL2r, R ARGSL, R FUMt2r, R SUCD1i).

d M fum c = v + v + v + v + v − v − v − v − v − v − v (2388) dt 50 51 100 429 925 112 417 418 419 420 428

7.339 Species M fum e

Name Fumarate

Charge -2

This species takes part in two reactions (as a reactant in R EX fum e, R FUMt2r).

d M fum e = −v − v (2389) dt 282 429

7.340 Species M g1p c

Name D-Glucose 1-phosphate

Charge -2

This species takes part in ﬁve reactions (as a reactant in R G1PTT, R GALUi, R GLGC, R PGMT and as a product in R GLCP).

d M g1p c = v − v − v − v − v (2390) dt 465 440 452 468 778

Produced by SBML2LATEX 945 7.341 Species M g3p c

Name Glyceraldehyde 3-phosphate

Charge -2

This species takes part in ten reactions (as a reactant in R DXPS, R GAPD, R TALA and as a product in R DRPA, R FBA, R TKT1, R TKT2, R TPI, R TRPS1, R TRPS3).

d M g3p c = v + v + v + v + v + v + v − v − v − v (2391) dt 244 399 952 953 966 973 975 251 454 929

7.342 Species M g3pe c

Name sn-Glycero-3-phosphoethanolamine

Charge 0

This species takes part in three reactions (as a reactant in R GPDDA2 and as a product in R- LPLIPAL2E160, R LPLIPAL2E180).

d M g3pe c = v + v − v (2392) dt 574 575 499

7.343 Species M g6p c

Name D-Glucose 6-phosphate

Charge -2

This species takes part in seven reactions (as a reactant in R G6PDH2, R MI1PS, R PGI, R TRE6PS and as a product in R HEX1, R PGMT, R PPGKr).

d M g6p c = v + v + v − v − v − v − v (2393) dt 523 778 819 448 615 772 969

7.344 Species M gal1p c

Name alpha-D-Galactose 1-phosphate

Charge -2

This species takes part in two reactions (as a reactant in R GALT and as a product in R GALKr).

d M gal1p c = v − v (2394) dt 450 451

946 Produced by SBML2LATEX 7.345 Species M gal c Name D-Galactose

Charge 0 This species takes part in four reactions (as a reactant in R GALKr, R biomass Mtb 9 60atp and as a product in R GALt2, R LACZ). d M gal c = v + v − v − 0.055474v (2395) dt 453 568 450 1025

7.346 Species M gal e Name D-Galactose

Charge 0 This species takes part in two reactions (as a reactant in R EX gal e, R GALt2). d M gal e = −v − v (2396) dt 283 453

7.347 Species M galfragund c Name galactofuranosyl(30)-rhamanosyl-N-acetylglucosamyl-undecaprenyl diphosphate (M tb)

Charge -2 This species takes part in two reactions (as a reactant in R AFTA and as a product in R GALFT). d M galfragund c = v − v (2397) dt 449 54

7.348 Species M gam1p c Name D-Glucosamine 1-phosphate

Charge -1 This species takes part in two reactions (as a reactant in R G1PACT, R PGAMT). d M gam1p c = −v − v (2398) dt 439 770

7.349 Species M gam6p c Name D-Glucosamine 6-phosphate

Charge -1 This species takes part in three reactions (as a product in R AGDC, R GF6PTAr, R PGAMT). d M gam6p c = v + v + v (2399) dt 55 460 770

Produced by SBML2LATEX 947 7.350 Species M gar c

Name N1-(5-Phospho-D-ribosyl)glycinamide

Charge -1

This species takes part in two reactions (as a reactant in R GARFT and as a product in R PRAGSr).

d M gar c = v − v (2400) dt 830 455

7.351 Species M gcald c

Name Glycolaldehyde

Charge 0

This species takes part in three reactions (as a product in R AHMMPS, R DHNPA, R DHNPA2).

d M gcald c = v + v + v (2401) dt 63 225 226

7.352 Species M gdp c

Name GDP

Charge -3

This species takes part in 22 reactions (as a reactant in R MAN1PT2, R NDPK1, R RNDR2 and as a product in R ADK3, R ADNK3, R ADSS, R CYTDK2, R FRRPPDIMAS, R G16MTM1, R G16MTM10, R- G16MTM2, R G16MTM6, R G16MTM7, R G16MTM8, R G16MTM9, R GK1, R GMT1, R GMT2, R HMPK4, R PEPCK re, R SADT2, R URIK2).

d M gdp c = v +v +v +v +v +v +v +v +v +v +v +v dt 39 44 52 183 424 430 431 432 435 436 437 438 (2402) + v464 + v496 + 3v497 + v531 + v766 + v894 + v1018 − v588 − v676 − v883

7.353 Species M gdpddman c

Name GDP-4-dehydro-6-deoxy-D-mannose

Charge -2

This species takes part in two reactions (as a reactant in R GFUCS and as a product in R GMAND).

d M gdpddman c = v − v (2403) dt 494 461

948 Produced by SBML2LATEX 7.354 Species M gdpfuc c

Name GDP-L-fucose

Charge -2

This species takes part in two reactions (as a reactant in R FRRPPDIMAS and as a product in R GFUCS). d M gdpfuc c = v − v (2404) dt 461 424

7.355 Species M gdpmann c

Name GDP-D-mannose

Charge -2

This species takes part in twelve reactions (as a reactant in R G16MTM1, R G16MTM10, R G16MTM2, R G16MTM6, R G16MTM7, R G16MTM8, R G16MTM9, R GMAND, R GMT1, R GMT2 and as a product in R MAN1PT, R MAN1PT2).

d M gdpmann c = v + v − v − v − v − v dt 587 588 430 431 432 435 (2405) − v436 − v437 − v438 − v494 − v496 − 3v497

7.356 Species M gdptp c

Name Guanosine 3’-diphosphate 5’-triphosphate

Charge -7

This species takes part in one reaction (as a product in R GTPDPK). d M gdptp c = v (2406) dt 509

7.357 Species M glc DASH D c

Name D-Glucose

Charge 0

This species takes part in six reactions (as a reactant in R HEX1, R PPGKr, R biomass Mtb 9- 60atp and as a product in R GLCabc, R LACZ, R MALT). d M glc DASH D c = v + v + 2v − v − v − 0.163152v (2407) dt 467 568 583 523 819 1025

Produced by SBML2LATEX 949 7.358 Species M glc DASH D e

Name D-Glucose

Charge 0

This species takes part in two reactions (as a reactant in R EX glc DASH D e, R GLCabc).

d M glc DASH D e = −v − v (2408) dt 284 467

7.359 Species M glcn c

Name D-Gluconate

Charge -1

This species takes part in one reaction (as a product in R 5DGLCNR).

d M glcn c = v (2409) dt 4

7.360 Species M gln DASH L c

Name L-Glutamine

Charge 0

This species takes part in 16 reactions (as a reactant in R ADCS, R ADCYRS, R ANS, R ASNS1, R CBPS, R CTPS2, R GF6PTAr, R GLUPRT, R GLUSy, R GMPS2, R IG3PS, R NADS2, R PRFGS, R R05224, R biomass Mtb 9 60atp and as a product in R GLNS).

d M gln DASH L c = v − v − 4v − v − v − v − v − v − v dt 469 35 36 87 106 133 170 460 477 (2410) − v479 − v495 − v547 − v670 − v842 − 2v874 − 0.05812v1025

7.361 Species M glu1sa c

Name L-Glutamate 1-semialdehyde

Charge 0

This species takes part in two reactions (as a reactant in R G1SATi and as a product in R GLUTRR).

d M glu1sa c = v − v (2411) dt 480 441

950 Produced by SBML2LATEX 7.362 Species M glu5p c

Name L-Glutamate 5-phosphate

Charge -2

This species takes part in three reactions (as a reactant in R G5SD, R G5SD2 and as a product in R GLU5K).

d M glu5p c = v − v − v (2412) dt 473 446 447

7.363 Species M glu5sa c

Name L-Glutamate 5-semialdehyde

Charge 0

This species takes part in four reactions (as a reactant in R G5SADs and as a product in R G5SD, R G5SD2, R ORNTA).

d M glu5sa c = v + v + v − v (2413) dt 446 447 729 445

7.364 Species M glu DASH D c

Name D-Glutamate

Charge -1

This species takes part in three reactions (as a reactant in R GLUR, R UAMAGS, R UGMAGS).

d M glu DASH D c = −v − v − v (2414) dt 478 990 1005

7.365 Species M glu DASH L c

Name L-Glutamate

Charge -1

This species takes part in 45 reactions (as a reactant in R ACGS, R DHFS, R GLNS, R GLU5K, R- GLUCYS, R GLUDC, R GLUDx, R HSTPT, R OHPBAT, R ORNTAC, R PSERT, R THFGLUS, R biomass- Mtb 9 60atp and as a product in R ABTA, R ACOTA, R ADCS, R ADCYRS, R ALATA L, R ANS, R ASNS1, R ASPTA, R CBPS, R CTPS2, R GF6PTAr, R GLUPRT, R GLUR, R GLUSy, R GLUt2r, R GMPS2, R IG3PS, R ILETA, R LEUTA, R NADS2, R OPAH, R ORNTA, R P5CD, R PHETA1, R- PRFGS, R R05224, R SDPTA, R SGDS, R SOTA, R TRPTA, R TYRTA, R VALTA).

Produced by SBML2LATEX 951 d M glu DASH L c = v + v + v + 4v + v + v + v + v + v + v dt 8 25 35 36 74 87 106 113 133 170 + v460 + v477 + v478 + 2v479 + v481 + v495 + v547 + v551 + v571 + v670 + v728 + v729 + v737 + v788 + v842 + 2v874 + v897 + v903 + v917 + v976 + v980 + v1019 − v19 − v222 − v469 − v473 − v474 − v475 − v476 − v540 − v725 − v730 − v851 − v944 − 0.090007v1025 (2415)

7.366 Species M glu DASH L e Name L-Glutamate

Charge -1

This species takes part in two reactions (as a reactant in R EX glu DASH L e, R GLUt2r). d M glu DASH L e = −v − v (2416) dt 285 481

7.367 Species M gluala c Name 5-L-Glutamyl-L-alanine

Charge -1

This species takes part in two reactions (as a reactant in R GGLUCT2 and as a product in R GTMLT). d M gluala c = v − v (2417) dt 505 462

7.368 Species M glucys c Name gamma-L-Glutamyl-L-cysteine

Charge -1

This species takes part in two reactions (as a reactant in R GTHS and as a product in R GLUCYS). d M glucys c = v − v (2418) dt 474 504

7.369 Species M glutrna c Name L-Glutamyl-tRNA(Glu)

Charge 0

This species takes part in one reaction (as a reactant in R GLUTRR). d M glutrna c = −v (2419) dt 480

952 Produced by SBML2LATEX 7.370 Species M glx c

Name Glyoxylate

Charge -1

This species takes part in seven reactions (as a reactant in R GLXO1, R MALS and as a product in R GLYCTO1, R GLYCTO2, R GLYCTO3, R GLYCTO4, R ICL).

d M glx c = v + v + v + v + v − v − v (2420) dt 487 488 489 490 545 482 582

7.371 Species M gly c

Name Glycine

Charge 0

This species takes part in eight reactions (as a reactant in R GCCa, R GLYCL, R GTHS, R PRAGSr, R biomass Mtb 9 60atp and as a product in R AMPTASECG, R GHMT2, R GLYt2r).

d M gly c = v + v + v − v − v − v − v − 0.335808v (2421) dt 85 463 493 457 486 504 830 1025

7.372 Species M gly e

Name Glycine

Charge 0

This species takes part in two reactions (as a reactant in R EX gly e, R GLYt2r).

d M gly e = −v − v (2422) dt 286 493

7.373 Species M glyb c

Name Glycine betaine

Charge 0

This species takes part in two reactions (as a product in R BETALDHx, R GLYBabc).

d M glyb c = v + v (2423) dt 122 483

Produced by SBML2LATEX 953 7.374 Species M glyb e

Name Glycine betaine

Charge 0

This species takes part in two reactions (as a reactant in R EX glyb e, R GLYBabc).

d M glyb e = −v − v (2424) dt 287 483

7.375 Species M glyc3p c

Name Glycerol 3-phosphate

Charge -2

This species takes part in nine reactions (as a reactant in R G3PAT160, R G3PAT190, R G3PD1, R PGSA160, R PGSA160190, R PGSA190 and as a product in R GLYC3Pabc, R GLYK, R GPDDA2).

d M glyc3p c = v + v + v − v − v − v − v − v − v (2425) dt 484 492 499 442 443 444 783 784 785

7.376 Species M glyc3p e

Name Glycerol 3-phosphate

Charge -2

This species takes part in two reactions (as a reactant in R EX glyc3p e, R GLYC3Pabc).

d M glyc3p e = −v − v (2426) dt 288 484

7.377 Species M glyc DASH R c

Name (R)-Glycerate

Charge -1

This species takes part in one reaction (as a reactant in R GLYCK).

d M glyc DASH R c = −v (2427) dt 485

954 Produced by SBML2LATEX 7.378 Species M glyc c

Name Glycerol

Charge 0

This species takes part in four reactions (as a reactant in R GLYCt, R GLYK, R biomass Mtb 9- 60atp and as a product in R CLPNS160190).

d M glyc c = v − v − v − 0.025359v (2428) dt 149 491 492 1025

7.379 Species M glyc e

Name Glycerol

Charge 0

This species takes part in two reactions (as a reactant in R EX glyc e and as a product in R- GLYCt).

d M glyc e = v − v (2429) dt 491 289

7.380 Species M glyclt c

Name Glycolate

Charge -1

This species takes part in ﬁve reactions (as a reactant in R GLYCTO1, R GLYCTO2, R GLYCTO3, R GLYCTO4 and as a product in R PGLYCP).

d M glyclt c = v − v − v − v − v (2430) dt 776 487 488 489 490

7.381 Species M glycogen c

Name glycogen

Charge 0

This species takes part in two reactions (as a reactant in R GLCP and as a product in R GLCS1).

d M glycogen c = v − v (2431) dt 466 465

Produced by SBML2LATEX 955 7.382 Species M gmp c

Name GMP

Charge -2

This species takes part in ten reactions (as a reactant in R GK1, R NTD9, R biomass Mtb 9- 60atp and as a product in R ADOCBLS, R GMPS2, R GSNK, R GTPH1, R GUAPRT, R NTPP2, R- PDE4).

d M gmp c = v +v +v +v +v +v +v −v −v −0.243651v (2432) dt 47 495 501 510 513 708 756 464 707 1025

7.383 Species M grdp c

Name Geranyl diphosphate

Charge -3

This species takes part in two reactions (as a reactant in R GRTT and as a product in R DMATT).

d M grdp c = v − v (2433) dt 236 500

7.384 Species M gsn c

Name Guanosine

Charge 0

This species takes part in four reactions (as a reactant in R GSNK, R PUNP3 and as a product in R NTD9, R NTPTP2).

d M gsn c = v + v − v − v (2434) dt 707 715 501 859

7.385 Species M gthox c

Name Oxidized glutathione

Charge -2

This species takes part in two reactions (as a reactant in R GTHOr, R MYCTR2).

d M gthox c = −v − v (2435) dt 502 664

956 Produced by SBML2LATEX 7.386 Species M gthrd c

Name Reduced glutathione

Charge -1

This species takes part in ﬁve reactions (as a reactant in R GTMLT and as a product in R GTHOr, R GTHRDt2, R GTHS, R MYCTR2). d M gthrd c = 2v + v + v + 2v − v (2436) dt 502 503 504 664 505

7.387 Species M gthrd e

Name Reduced glutathione

Charge -1

This species takes part in two reactions (as a reactant in R EX gthrd e, R GTHRDt2). d M gthrd e = −v − v (2437) dt 290 503

7.388 Species M gtp c

Name GTP

Charge -4

This species takes part in 19 reactions (as a reactant in R ACBIPGT, R ADK3, R ADNK3, R- ADSS, R CYTDK2, R GTPCI, R GTPCII, R GTPCII2, R GTPDPK, R GTPH1, R GUACYC, R HMPK4, R MAN1PT, R NTPP2, R NTPTP2, R PEPCK re, R SADT2, R URIK2 and as a product in R NDPK1).

d M gtp c = v − v − v − v − v − v − v − v − v − v dt 676 12 39 44 52 183 506 507 508 509 (2438) − v510 − v511 − v531 − v587 − v708 − v715 − v766 − v894 − v1018

7.389 Species M gua c

Name Guanine

Charge 0

This species takes part in four reactions (as a reactant in R GUAD, R GUAPRT and as a product in R PUNP3, R PUNP4). d M gua c = v + v − v − v (2439) dt 859 860 512 513

Produced by SBML2LATEX 957 7.390 Species M h2 c

Name H2

Charge 0

This species takes part in three reactions (as a reactant in R ECHH 0, R H2td and as a product in R FHL).

d M h2 c = v − v − v (2440) dt 410 253 518

7.391 Species M h2 e

Name H2

Charge 0

This species takes part in two reactions (as a reactant in R EX h2 e and as a product in R H2td).

d M h2 e = v − v (2441) dt 518 291

7.392 Species M h2co3 c

Name carbonic acid

Charge 0

This species takes part in two reactions (as a product in R H2CO3D, R H2CO3TP).

d M h2co3 c = v + v (2442) dt 514 515

7.393 Species M h2co3 e

Name carbonic acid

Charge 0

This species takes part in two reactions (as a reactant in R EX h2co3 e, R H2CO3TP).

d M h2co3 e = −v − v (2443) dt 292 515

958 Produced by SBML2LATEX 7.394 Species M h2mb4p c Name 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate

Charge -3

This species takes part in three reactions (as a reactant in R DMPPS, R IPDPS and as a product in R MECDPDH). d M h2mb4p c = v − v − v (2444) dt 601 237 559

7.395 Species M h2o2 c Name Hydrogen peroxide

Charge 0

This species takes part in 13 reactions (as a reactant in R CAT, R METOX1s, R METOX2s, R- PRDX and as a product in R ASPO1, R DALAOX, R GLYCTO1, R PDX5PO, R PEAMNO, R PYAM5PO, R PYDXNO, R PYDXO, R SPODM).

d M h2o2 c = v + v + v + v + v + v + v dt 111 193 487 764 765 864 865 (2445) + 2v866 + v919 − 2v129 − v606 − v607 − v836

7.396 Species M h2o c Name H2O

Charge 0

This species takes part in 323 reactions (as a reactant in R 4HTHRS, R ACODA, R ACP1 FMN, R ADA, R ADCYRS, R AGDC, R AGMT, R AHC, R AHCYSNS, R ALAALAD, R ALAD L, R ALDD1, R- ALDD19x, R ALDD2x, R AMID4, R AMPTASECG, R ARB Dabc, R ARBabc, R ARGDr, R ASNN, R- ASNS1, R ASPO1, R ATPS1, R BETALDHx, R BPNT, R CAATPS, R CBPS, R CDAPPA160, R CDAPPA160190, R CDAPPA190, R CHLabc, R CITabc, R COCHL, R CODH2r, R CODH3, R CRNabc, R CS, R CTPS2, R CYSTGL, R CYSTL, R CYTD, R Cuabc, R Cut1, R DADA, R DALAOX, R DCPDP, R DCPDPP, R- DCPDPP2, R DCTPD, R DCTPD2, R DCYTD, R DDPA, R DHORTS, R DHPPDA, R DHPPDA2, R DNMPPA, R DNTPPA, R DUTPDP, R E4PD, R FACOAE140, R FACOAE160, R FACOAE180, R FAO1, R FAO10, R FAO11, R FAO2, R FAO3, R FBP, R FCOAH2, R FE2abc, R FE3abc, R FTHFD, R FUM, R GALFT, R GLCabc, R GLUDx, R GLUPRT, R GLXO1, R GLYBabc, R GLYC3Pabc, R GMPS2, R GPDDA2, R- GTPCI, R GTPCII, R GTPCII2, R GTPH1, R GUAD, R H2CO3D, R HCO3E, R HISTD, R HISTP, R HMBS, R IGAMD, R IMPC, R IMPD, R INSH, R IPPMIb, R IPPS, R Kabc, R LACZ, R LCTSabc, R LPLIPAL2E160, R LPLIPAL2E180, R MALS, R MALT, R MALTHPabc, R MALTabc, R METAT, R METabc, R MI1PP, R MI3PP, R MI4PP, R MN6PP, R MOHMT, R MOTH, R MPML, R MSHAMID, R- MSHOXH, R MTAN, R MTHFC, R MYC1M1, R MYC1M2, R MYCON1, R MYCON2, R MYCON3, R MYCON4,

Produced by SBML2LATEX 959 R MYCON5, R NADS2, R NNAM, R NTD1, R NTD10, R NTD11, R NTD2, R NTD3, R NTD4, R NTD5, R NTD6, R NTD7, R NTD8, R NTD9, R NTPP2, R NTPP3, R NTPP4, R NTPP5, R NTPP7, R NTPP8, R NTPTP1, R NTPTP2, R OPAH, R P5CD, R PAPA160, R PDE1, R PDE4, R PEAMNO, R PGL, R- PGLYCP, R PGPP160, R PGPP160190, R PGPP190, R PIabc, R PLCD, R PLIPA1E160, R PLIPA1E180, R PMDPHT, R PPA, R PRAMPC, R PRATPP, R PREPHACPH, R PREPPACPH, R PRFGS, R PROabc, R- PSP L, R PYAM5PO, R PYDXO, R R05219, R R05224, R RIBabc, R RZ5PP, R SADH, R SADT2, R SDPDS, R SGDS, R SGSAD, R SHSL4r, R SSALx, R SSALy, R SULR, R SULabc, R THDPS, R- THMDP, R THRS, R TMN, R TRE6PP, R TREabc, R TSULabc, R UDCPDP, R UDPGD, R UREA, R- XYLabc, R biomass Mtb 9 60atp and as a product in R ACCC, R ACChex, R AFE, R ARABF, R ATPS4r, R CAT, R CPPPGO, R CYO1b, R CYSTS, R CYTBD, R CYTBD2, R DESAT16, R DESAT18, R DHAD1, R DHAD2, R DHDPS, R DHQD, R DMPPS, R ENO, R FAH4, R FAS100, R FAS120, R FAS140, R FAS160, R FAS161, R FAS180, R FAS181, R FAS200, R FAS240 L, R FAS260, R FAS80 L, R FASPHDCA, R FASm1601, R FASm180, R FASm1801, R FASm2001, R FASm2002, R FASm220, R FASm2201, R FASm2202, R FASm240, R FASm2401, R FASm2402, R FASm260, R FASm2601, R FASm2602, R FASm280, R FASm2801, R FASm2802, R FASm300, R FASm3001, R FASm320, R FASm340, R FOMETR, R G5SADs, R GHMT2, R GMAND, R H2Ot, R IGPDH, R IGPS, R IPDPS, R- IPPMIa, R LO, R MCBTS, R MCBTS2, R MCBTS3, R MECDPDH, R METOX1s, R METOX2s, R METSOXR1, R METSOXR2, R MNDNS1, R MNDNS2, R MYCSacp50, R MYCSacp56, R MYCSacp58, R NH4OHDs, R NO3R1, R NO3R2, R NTRIR2x, R NTRIRx, R NTRIRy, R PATS, R PDIMAS, R PHTHCLS, R PPBNGS, R PPDIMAS, R PPGKr, R PPNDH, R PPPGO, R PRDX, R PREPTHS, R PREPTHS2, R QULNS, R RBFSa, R RNDR1, R RNDR2, R RNDR3, R RNDR4, R RNTR4, R SUCBZS, R TARTD, R TATS, R TATSO, R- TDMS1, R TDMS2, R TDMS3, R TDMS4, R TDPGDH, R THZPSN, R THZSN, R TMHAS1, R TMHAS2, R TMHAS3, R TMHAS4, R TMHAS5, R TMHAS6, R TRIATS, R TRPS1, R TRPS2, R UAMRH, R UPP3S, R YUMPS).

960 Produced by SBML2LATEX d M h2o c = v + v + v + 32v + v + 2v + 2v + v + v + v + v + 2v dt 13 15 53 91 118 129 166 173 179 180 181 213 +2v214 +v217 +v218 +2v220 +v234 +v237 +v254 +v355 +v366 +v367 +v368 +v369 + 3v370 + v371 + 3v372 + v373 + 3v374 + v375 + 2v376 + 8v377 + v378 + 5v379 + v380 + v381 + v382 + v383 + v384 + v385 + v386 + v387 + v388 + v389 + v390 + v391 + v392 + v393 + v394 + v395 + v396 + v397 + v398 + v415 + v445 + v463 + v494 + v516 + v549 +v550 +v559 +v561 +v573 +5v593 +5v594 +5v595 +v601 +v606 +v607 +v609 +v610 + 2v625 + 2v626 + 13v660 + 16v661 + 17v662 + v685 + v692 + v693 + 2v716 + v717 + v718 + 5v747 + 2v762 + v792 + 2v811 + 2v816 + v819 + v825 + 3v826 + 2v836 + 5v839 + 5v840 + 2v871 + 2v876 + v882 + v883 + v884 + v885 + v886 + v923 + v930 + 4v933 +4v934 +2v935 +2v936 +2v937 +2v938 +v941 +v950 +v951 +2v957 +2v958 +2v959 +2v960 +2v961 +2v962 +3v972 +v973 +v974 +v992 +v1011 +v1024 −v3 −v23 −v26 − v31 − 4v36 − v55 − v56 − v61 − v62 − v70 − v72 − v77 − v78 − v79 − v81 − v85 − v95 −v96 −v99 −v105 −v106 −v111 −v117 −v122 −v125 −v128 −v133 −v134 −v135 −v136 − v140 − v148 − v156 − v157 − 2v158 − v167 − v168 − v170 − v177 − v178 − v182 − v188 − v189 − v190 − v193 − v202 − v203 − v204 − v209 − v210 − v211 − v212 − v230 − v231 −v232 −v239 −v240 −v249 −v252 −v343 −v344 −v345 −6v361 −8v362 −7v363 −7v364 − 8v365 − v400 − v404 − v406 − v408 − v426 − v428 − v449 − v467 − v476 − v477 − v482 −v483 −v484 −v495 −v499 −v506 −3v507 −3v508 −2v510 −v512 −v514 −v520 −v524 −v525 −v527 −v548 −v553 −v554 −v556 −v562 −v563 −v566 −v568 −v569 −v574 −v575 −v582 −v583 −v584 −v585 −v605 −v611 −v614 −v616 −v617 −v624 −v627 −v628 −v630 − v631 − v632 − v634 − v635 − v645 − v646 − 2v655 − 2v656 − 2v657 − 2v658 − 2v659 −v670 −v687 −v697 −v698 −v699 −v700 −v701 −v702 −v703 −v704 −v705 −v706 −v707 −v708 −v709 −v710 −v711 −v712 −v713 −v714 −v715 −2v728 −2v737 −v742 −v755 −v756 −v765 −v774 −v776 −v779 −v780 −v781 −v799 −v801 −v802 −v803 −v805 −v809 − v833 − v835 − v837 − v838 − v842 − v845 − v852 − v864 − 2v866 − v873 − v874 − v881 −v891 −2v892 −v894 −v896 −v903 −v904 −v915 −v920 −v921 −3v927 −v928 −v943 − 2v945 − v947 − v963 − v968 − v971 − v978 − v994 − v1000 − v1015 − v1023 − 60v1025 (2446)

7.397 Species M h2o e

Name H2O

Charge 0

This species takes part in two reactions (as a reactant in R EX h2o e, R H2Ot).

d M h2o e = −v − v (2447) dt 293 516

Produced by SBML2LATEX 961 7.398 Species M h2s c

Name Hydrogen sulﬁde

Charge 0

This species takes part in four reactions (as a reactant in R CYSS, R H2St1, R SULR and as a product in R BTS3r).

d M h2s c = v − v − v − v (2448) dt 127 176 517 927

7.399 Species M h2s e

Name Hydrogen sulﬁde

Charge 0

This species takes part in two reactions (as a reactant in R EX h2s e and as a product in R- H2St1).

d M h2s e = v − v (2449) dt 517 294

7.400 Species M h c

Name H+

Charge 1

This species takes part in 526 reactions (as a reactant in R 5DGLCNR, R ACBIPGT, R ACChex, R ACHBS, R ACLS, R ADA, R ADMDCr, R AHMMPS, R AMMQT8, R AOXSr, R APRAUR, R ARGDC, R- ASP1DC, R ATPS1, R BACCL, R CBIAT, R CBLAT, R CPC6R, R CPPPGO, R CYO1a, R CYRDAAT, R CYTBD, R CYTBD2, R CYTD, R DADA, R DAPDC, R DASYN160, R DASYN160190, R DASYN190190, R DCTPD, R DCTPD2, R DCYTD, R DESAT16, R DESAT18, R DHDPRy, R DHFR, R DHPPDA, R DHPPDA2, R DMPPS, R DPR, R DXPRIi, R DXPS, R FAH4, R FAMPL1, R FAMPL2, R FAMPL3, R FAMPL4, R- FAMPL5, R FAS100, R FAS120, R FAS140, R FAS160, R FAS161, R FAS180, R FAS181, R- FAS200, R FAS240 L, R FAS260, R FAS80 L, R FASPHDCA, R FASm1601, R FASm180, R FASm1801, R FASm2001, R FASm2002, R FASm220, R FASm2201, R FASm2202, R FASm240, R FASm2401, R FASm2402, R FASm260, R FASm2601, R FASm2602, R FASm280, R FASm2801, R FASm2802, R FASm300, R FASm3001, R FASm320, R FASm340, R FHL, R FMNAT, R FOMETR, R G1PTT, R- G5SD, R G5SD2, R GALT, R GALUi, R GCCa, R GFUCS, R GLGC, R GLUDC, R GLUSy, R GLUTRR, R GTHOr, R GUAD, R IGPS, R INDPYRD, R IPDPS, R KARA1i, R KARA2i, R MAN1PT, R MAN1PT2, R MCBTS, R MCBTS2, R MCD, R MECDPDH, R MEPCT, R MMCD, R MNDNS1, R MNDNS2, R MTHFR2, R MYCSacp50, R MYCSacp56, R MYCSacp58, R NADH10, R NADH2r, R NADH5, R NADH9, R- NAPRTr, R NH4OHDs, R NNAT, R NNDPR, R NO3R1, R NO3R2, R NTRIR2x, R NTRIRx, R NTRIRy,

962 Produced by SBML2LATEX R OMCDC, R OMPDC, R OXCDC, R OXGDC, R OXGDC2, R P5CR, R P5CRx, R PATS, R PC6AR, R- PC8XM, R PDHa, R PDIMAS, R PHTHCLS, R PHTHDLS, R PHTHDLS2, R PHYCBOXL, R PNCDC, R- PPCDC, R PPDIMAS, R PPNDH, R PREPTHS, R PREPTHS2, R PSD160, R PSD180, R PTPATi, R- PYK, R PYRDC, R QRr, R R05217, R SADH, R SADT, R SHK3Dr, R SPODM, R TATS, R TATSO, R TDMS1, R TDMS2, R TDMS3, R TDMS4, R TDPDRR, R TMPPP, R TRDR, R TRIATS, R UAGDP, R- UAMRH, R UAPGR, R UPPDC1, R UPPDC2, R UREA and as a product in R ACALDi, R ACCOACr, R ACGS, R ACPS1, R ADCL, R ADCPS1, R ADCPS2, R ADCYRS, R ADNK1, R ADNK3, R ADNK4, R- ADOCBIK, R ADOCBLS, R ADSK, R ADSS, R AGPR, R AIRC2, R AIRCr, R ALAALAr, R ALAD L, R ALAt2r, R ALDD1, R ALDD19x, R ALDD2x, R AMMQT6, R AMMQT8 2, R ANS, R ARB Dabc, R- ARBabc, R ARBt2r, R ARGSS, R ASAD, R ASNS1, R ASNt2r, R ASPCT, R ASPO5, R ASPt2r, R AST, R ATPS4r, R BALAt2r, R BDH, R BETALDHx, R BMNMSHS, R BTS2, R CAt4, R CBPS, R- CDAPPA160, R CDAPPA160190, R CDAPPA190, R CDPMEK, R CDPPT160, R CDPPT160190, R- CHLabc, R CHOLD, R CIGAMS, R CITabc, R CMLDC, R COCHL, R CODH2r, R CODH3, R CPC2MT, R CPC4MT, R CPC6MT, R CRNabc, R CS, R CTPS1, R CTPS2, R CYANST, R CYRDAR, R CYSS, R- CYTDK2, R CYTDt2r, R Cuabc, R Cut1, R DAGK160, R DALAt2r, R DB4PS, R DBTSr, R DCPDP, R DGC3D, R DHDPS, R DHFS, R DHNAOT, R DHNAOT2, R DHNPA, R DHORTS, R DNTPPA, R DPCOAK, R DSERt2r, R DURIK1, R DUTPDP, R E4PD, R ECHH 0, R ENTCS, R FACOAE140, R FACOAE160, R FACOAE180, R FAO1, R FAO10, R FAO11, R FAO2, R FAO3, R FCLT, R FCLT2, R FCOAH2, R FE2abc, R FE3Ri, R FE3abc, R FMETTRS, R FRDOr, R FRRPPDIMAS, R FTHFD, R FUMt2r, R G16MTM1, R G16MTM10, R G16MTM2, R G16MTM4, R G16MTM5, R G16MTM6, R G16MTM7, R- G16MTM8, R G16MTM9, R G1PACT, R G3PD1, R G5SADs, R G6PDH2, R GALFT, R GALKr, R GALt2, R GAPD, R GARFT, R GCCc, R GLCS1, R GLCabc, R GLNS, R GLNSP1, R GLNSP2, R GLNSP3, R GLUCYS, R GLUDx, R GLUt2r, R GLXO1, R GLYBabc, R GLYC3Pabc, R GLYCK, R GLYK, R- GLYt2r, R GMPS2, R GMT2, R GPDDA2, R GSNK, R GTHS, R GTPCI, R GTPCII, R GTPCII2, R- GTPDPK, R GTPH1, R HCO3E, R HCYSMT, R HDCAt2, R HEX1, R HISTD, R HISt2r, R HMPK1, R- HMPK2, R HMPK3, R HMPK4, R HPPK, R HPPK2, R HSDx, R HSDy, R HSK, R IG3PS, R ILEt2r, R- IMPD, R INSK, R IPMD, R IPPS, R Kabc, R Kt3r, R LCTSabc, R LDH L, R LEUt2r, R LPLIPAL2E160, R LPLIPAL2E180, R L LACt2r, R L LACt3, R MALS, R MALTHPabc, R MALTabc, R MALt2r, R MCBTS3, R MDFDH, R MDH, R METS, R METabc, R MMSAD2, R MPML, R MSHOXH, R MTHFC, R- MYC1CYC1, R MYC1CYC2, R MYC1CYC3, R MYC1CYC4, R MYC1CYC5, R MYC1M1, R MYC1M2, R- MYC2CYC1, R MYC2CYC2, R MYC2CYC3, R MYCON1, R MYCON2, R MYCON3, R MYCON4, R MYCON5, R MYCTR, R NADK, R NADS2, R NAt3 1, R NNDMBRT, R NTPP2, R NTPP3, R NTPP4, R NTPP5, R NTPP7, R NTPP8, R O16RHAT, R OCBT, R OCDCAt2, R OPAH, R P5CD, R PACt2r, R PANTS, R PAPR, R PC, R PC11M, R PC17M, R PC20M, R PC6YM, R PDE1, R PDE4, R PDHc, R PDHcr, R- PERD, R PFK, R PGCD, R PGL, R PGLS, R PGSA160, R PGSA160190, R PGSA190, R PHEt2r, R- PHTHCLR1, R PHTHCLR2, R PHTO, R PIabc, R PLCD, R PLIPA1E160, R PLIPA1E180, R PNTK, R PPA, R PPBNGS, R PPCOAC, R PPDK, R PPNCL, R PPNCL2, R PPNCL3, R PPTGS, R PPTGS- TB1, R PPTGS TB2, R PRAGSr, R PRAIS, R PRASCS, R PRATPP, R PREPHACPH, R PREPPACPH, R PRFGS, R PROD2, R PROabc, R PROt2r, R PRPPS, R PSSA160, R PSSA180, R PYRt2r, R- R05219, R R05224, R RBFK, R RBK, R RBK Dr, R RBK L1r, R RIBabc, R RPPDIMAS, R RRPPDIMAS, R SELCYSLY, R SERt2r, R SGSAD, R SHCHD2, R SHCHD3, R SHCHF, R SHCHF2, R SHCHF3, R- SHKK, R SHSL1r, R SHSL4r, R SKMt2, R SPMS, R SSALx, R SSALy, R SUCCt2r, R SULR, R- SULabc, R THFGLUS, R THMDP, R THRt2r, R THSFST, R THZPSN, R THZSN, R TMDK1, R TMN,

Produced by SBML2LATEX 963 R TRE6PS, R TRESULT, R TREabc, R TRPt2r, R TSULabc, R TTDCAt2, R TYRt2r, R UAAGDS, R UAAGLS1, R UAAGLS2, R UAGPT1, R UAGPT2, R UAGPT3, R UAMAGS, R UAMAS, R UDCPDP, R UDPGD, R UGAGDS, R UGGPT3, R UGMAGS, R UGMAS, R UGMDDS, R UGMDDS2, R UPP3MT, R- URIK2, R VALt2r, R XYLK, R XYLabc, R biomass Mtb 9 60atp).

964 Produced by SBML2LATEX d M h c = v +v +v +v +v +v +v +4v +v +v +v +v +v +v +2v dt 11 14 19 27 32 33 34 36 43 44 45 46 47 49 52 +v60 +v66 +v68 +v71 +v72 +v76 +2v77 +2v78 +2v79 +v82 +v84 +v87 +v95 +v96 +v97 +v101 +v104 +v106 +v107 +v109 +v112 +v114 +v115 +3v118 +v120 +v121 +2v122 +2v123 +2v126 +v130 +2v133 +2v134 +2v135 +2v136 +v137 +v138 +v139 +v140 +v141 +2v145 +v148 +v152 +2v156 +2v157 +2v158 +v160 +v162 +v163 +v167 +v168 +2v169 +2v170 +v171 +v175 +v176 +v183 +v184 +v188 +v189 +v192 +v194 +v200 +3v201 +v202 +v215 +v220 +v222 +v223 +v224 + v225 + v230 + v240 + v241 + v245 + v247 + v249 + 2v252 + 2v253 + 9v255 + v343 + v344 + v345 + 6v361 + 8v362 + 7v363 + 7v364 + 8v365 + 2v402 + 2v403 + v404 + v406 + 2v407 + v408 + v411 +v423 +v424 +v426 +v429 +v430 +v431 +v432 +v433 +v434 +v435 +v436 +v437 +v438 +v439 + v444 + v445 + v448 + 30v449 + v450 + v453 + v454 + v455 + v459 + v466 + v467 + v469 + v470 + v471 + v472 + v474 + v476 + v481 + 2v482 + v483 + v484 + v485 + v492 + v493 + 2v495 + 3v497 +v499 +v501 +v504 +v506 +2v507 +2v508 +v509 +2v510 +v520 +v521 +v522 +v523 +3v524 +v526 +v528 +v529 +v530 +v531 +v533 +v534 +v535 +v536 +v538 +v547 +v552 +v554 +v557 +v560 +v563 +v566 +v567 +v569 +v570 +v572 +v574 +v575 +v580 +v581 +v582 +v584 +v585 + v586 + 2v595 + v598 + v599 + v608 + v611 + v622 + 3v630 + v632 + v635 + v640 + v641 + v642 +v643 +v644 +v645 +v646 +v647 +v648 +v649 +2v655 +2v656 +2v657 +2v658 +2v659 +v663 +v669 +v670 +v675 +v689 +v708 +v709 +v710 +v711 +v712 +v713 +v719 +v721 +v722 +v728 + v737 + v740 + v741 + 2v746 + v748 + v749 + 3v750 + v751 + 2v753 + v755 + v756 + v760 + v761 + v767 + v768 + v771 + v774 + 4v775 + v783 + v784 + v785 + v789 + v790 + v791 + 2v797 + v799 +v801 +v802 +v803 +v808 +v809 +v811 +v814 +v818 +v821 +v822 +v823 +v827 +v828 +v829 + v830 + 2v831 + v834 + v835 + v837 + v838 + v842 + v844 + v845 + v846 + v847 + v853 + v854 +v869 +v873 +v874 +v875 +v878 +v879 +v880 +v881 +v889 +v890 +v898 +v902 +2v904 +v907 +v908 +3v909 +2v910 +3v911 +v913 +v914 +v915 +v916 +v918 +2v920 +2v921 +v924 +5v927 +v928 +v944 +v945 +v948 +v949 +v950 +v951 +v954 +v963 +v969 +v970 +v971 +v977 +v978 + v979 + v981 + v982 + v983 + v984 + v987 + v988 + v989 + v990 + v991 + v994 + 3v1000 + v1001 + v1002 + v1005 + v1006 + v1007 + v1008 + v1010 + v1018 + v1020 + v1022 + v1023 + 60v1025 − v4 −v12 −v15 −v20 −v22 −v31 −v41 −2v63 −v83 −v88 −v90 −v98 −v108 −v117 −v119 −v131 −v132 −v164 −2v166 −2v172 −v174 −2v180 −2v181 −v182 −v190 −v195 −v197 −v198 −v199 −v209 −v210 −v211 −v213 −v214 −v219 −v221 −v231 −v232 −v237 −v243 −v250 −v251 −v355 − v356 − v357 − v358 − v359 − v360 − 3v366 − 3v367 − 3v368 − 3v369 − 4v370 − 3v371 − 4v372 − 3v373 − 9v374 − 3v375 − 8v376 − 24v377 − 3v378 − 15v379 − 3v380 − 3v381 − 3v382 − 3v383 − 3v384 − 3v385 − 3v386 − 3v387 − 3v388 − 3v389 − 3v390 − 3v391 − 3v392 − 3v393 − 3v394 −3v395 −3v396 −3v397 −3v398 −v410 −v412 −v415 −v440 −v446 −v447 −v451 −v452 −v457 −v461 −v468 −v475 −v479 −v480 −v502 −v512 −v550 −v555 −v559 −v564 −v565 −v587 −v588 −v593 −v594 −v596 −v601 −v604 −v618 −3v625 −3v626 −2v638 −33v660 −42v661 −47v662 − v665 − v666 − v667 − v668 − v673 − v685 − v688 − 2v690 − 2v692 − 2v693 − 5v716 − 4v717 −4v718 −v726 −v727 −v734 −v735 −v736 −2v738 −2v739 −5v747 −v752 −v754 −v758 −2v762 −v792 −v793 −v794 −v798 −v807 −v812 −2v816 −v825 −14v839 −14v840 −v849 −v850 −v856 − v867 − v868 − v870 − v872 − 2v892 − v893 − v912 − 2v919 − 4v933 − 4v934 − 2v935 − 2v936 − 2v937 − 2v938 − v940 − v965 − v967 − 3v972 − v986 − v992 − v993 − 4v1012 − 4v1013 − 2v1015 (2450)

Produced by SBML2LATEX 965 7.401 Species M h e

Name H+

Charge 1

This species takes part in 44 reactions (as a reactant in R ALAt2r, R ARBt2r, R ASNt2r, R- ASPt2r, R ATPS4r, R BALAt2r, R CAt4, R CYTDt2r, R DALAt2r, R DSERt2r, R EX h e, R- FUMt2r, R GALt2, R GLUt2r, R GLYt2r, R HDCAt2, R HISt2r, R ILEt2r, R Kt3r, R LEUt2r, R L LACt2r, R L LACt3, R MALt2r, R NAt3 1, R OCDCAt2, R PACt2r, R PHEt2r, R PROt2r, R PYRt2r, R SERt2r, R SKMt2, R SUCCt2r, R THRt2r, R TRPt2r, R TTDCAt2, R TYRt2r, R- VALt2r and as a product in R ATPS1, R CAATPS, R CYO1a, R CYTBD, R CYTBD2, R NO3R1, R NO3R2).

d M h e = 2v + v + 2v + 2v + 2v + 2v + 2v − v − v − v − v dt 117 128 172 180 181 692 693 76 97 107 114 − 4v118 − v120 − v130 − v184 − v194 − v245 − v295 − v429 − v453 − v481 − v493 − v522 − v526 − v552 − v567 − v572 − v580 − v581 − v586 − v675 − v722 − v740 − v789 − v846 − v869 − v902 − v916 − v924 − v948 − v977 − v979 − v981 − v1020 (2451)

7.402 Species M harab DASH D c

Name hexa arabinofuranoside

Charge 0

This species takes part in two reactions (as a reactant in R GMT2 and as a product in R HAS).

d M harab DASH D c = v − v (2452) dt 519 497

7.403 Species M hco3 c

Name Bicarbonate

Charge -1

This species takes part in six reactions (as a reactant in R ACCOACr, R AIRC2, R CBPS, R PC, R PPCOAC and as a product in R HCO3E).

d M hco3 c = v − v − v − v − v − v (2453) dt 520 14 66 133 748 814

966 Produced by SBML2LATEX 7.404 Species M hcys DASH L c

Name L-Homocysteine

Charge 0

This species takes part in six reactions (as a reactant in R CYSTS, R HCYSMT, R METS, R MHPGLUT and as a product in R AHC, R CYSTL). d M hcys DASH L c = v + v − v − v − v − v (2454) dt 61 178 179 521 608 613

7.405 Species M hdca c

Name Hexadecanoate (n-C16:0)

Charge -1

This species takes part in 15 reactions (as a reactant in R 2AGPEAT160, R AACPS3, R FACOAL160, R FAO2, R FAS180, R FAS181, R FASm1601, R TATS, R TATSO, R biomass Mtb 9 60atp and as a product in R FACOAE160, R FAS160, R HDCAt2, R LPLIPAL2E160, R PLIPA1E160).

d M hdca c = v + v + v + v + v − v − v − v − v dt 344 369 522 574 802 1 7 347 364 (2455) − v371 − v372 − v378 − v933 − v934 − 0.235152v1025

7.406 Species M hdca e

Name Hexadecanoate (n-C16:0)

Charge -1

This species takes part in two reactions (as a reactant in R EX hdca e, R HDCAt2). d M hdca e = −v − v (2456) dt 296 522

7.407 Species M hdcea c

Name Hexadecenoate (n-C16:1)

Charge -1

This species takes part in four reactions (as a reactant in R FACOAL161, R FAO11, R biomass- Mtb 9 60atp and as a product in R FAS161). d M hdcea c = v − v − v − 0.01094v (2457) dt 370 348 363 1025

Produced by SBML2LATEX 967 7.408 Species M hdcoa c Name Hexadecenoyl-CoA (n-C16:1CoA)

Charge -4 This species takes part in two reactions (as a product in R DESAT16, R FACOAL161). d M hdcoa c = v + v (2458) dt 213 348

7.409 Species M hexc c Name hexacosanoate (n-C26:0)

Charge -1 This species takes part in six reactions (as a reactant in R ACChex, R MYCSacp50, R MYCSacp56, R MYCSacp58, R biomass Mtb 9 60atp and as a product in R FAS260). d M hexc c = v − v − v − v − v − 0.058352v (2459) dt 375 15 660 661 662 1025

7.410 Species M hexccoa c Name Hexacosanoyl-CoA (n-C26:0CoA)

Charge -4 This species takes part in two reactions (as a reactant in R ACCC and as a product in R ACChex). d M hexccoa c = v − v (2460) dt 15 13

7.411 Species M hgbam c Name Hydrogenobyrinate a,c diamide

Charge -5 This species takes part in two reactions (as a reactant in R COCHL and as a product in R R05224). d M hgbam c = v − v (2461) dt 874 156

7.412 Species M hgbyr c Name Hydrogenobyrinate

Charge -6 This species takes part in two reactions (as a reactant in R R05224 and as a product in R PC8XM). d M hgbyr c = v − v (2462) dt 754 874

968 Produced by SBML2LATEX 7.413 Species M his DASH L c Name L-Histidine

Charge 0 This species takes part in three reactions (as a reactant in R biomass Mtb 9 60atp and as a product in R HISTD, R HISt2r). d M his DASH L c = v + v − 0.040617v (2463) dt 524 526 1025

7.414 Species M his DASH L e Name L-Histidine

Charge 0 This species takes part in two reactions (as a reactant in R EX his DASH L e, R HISt2r). d M his DASH L e = −v − v (2464) dt 297 526

7.415 Species M hisp c Name L-Histidinol phosphate

Charge -1 This species takes part in two reactions (as a reactant in R HISTP and as a product in R HSTPT). d M hisp c = v − v (2465) dt 540 525

7.416 Species M histd c Name L-Histidinol

Charge 1 This species takes part in two reactions (as a reactant in R HISTD and as a product in R HISTP). d M histd c = v − v (2466) dt 525 524

7.417 Species M hmbil c Name Hydroxymethylbilane

Charge -8 This species takes part in two reactions (as a reactant in R UPP3S and as a product in R HMBS). d M hmbil c = v − v (2467) dt 527 1011

Produced by SBML2LATEX 969 7.418 Species M hmocta c

Name hexa-methyl octacosanoate

Charge -1

This species takes part in two reactions (as a reactant in R FASm2801 and as a product in R- FASm2601).

d M hmocta c = v − v (2468) dt 390 393

7.419 Species M hmtria c

Name hexa-methyl triacontanoic acid (C30:0, plus 6 methyl branches)

Charge -1

This species takes part in two reactions (as a reactant in R FASm320 and as a product in R- FASm300).

d M hmtria c = v − v (2469) dt 395 397

7.420 Species M hom DASH L c

Name L-Homoserine

Charge 0

This species takes part in ﬁve reactions (as a reactant in R HSDx, R HSDy, R HSERTA, R HSK, R HSST).

d M hom DASH L c = −v − v − v − v − v (2470) dt 535 536 537 538 539

7.421 Species M homtta c

Name 10 hydroxy octa-methyl tetracontatricosanoic acid (C34:0, 8 methyl-branched carbons, 1 hydroxylated carbon)

Charge -1

This species takes part in one reaction (as a product in R FAH4).

d M homtta c = v (2471) dt 355

970 Produced by SBML2LATEX 7.422 Species M hpglu c

Name Tetrahydropteroyltri-L-glutamate

Charge 0

This species takes part in one reaction (as a product in R MHPGLUT).

d M hpglu c = v (2472) dt 613

7.423 Species M hpmdtria c

Name hepta-methyl dotriacontanoic acid (7 methyl branches)

Charge -1

This species takes part in two reactions (as a reactant in R FASm340 and as a product in R- FASm320).

d M hpmdtria c = v − v (2473) dt 397 398

7.424 Species M hpmtria c

Name hepta-methyl triacontanoic acid (C30:0, plus 7 methyl branches)

Charge -1

This species takes part in four reactions (as a reactant in R FASm3001, R TATS, R TATSO and as a product in R FASm2801).

d M hpmtria c = v − v − v − v (2474) dt 393 396 933 934

7.425 Species M hxan c

Name Hypoxanthine

Charge 0

This species takes part in four reactions (as a reactant in R HXPRT and as a product in R INSH, R PUNP5, R PUNP6).

d M hxan c = v + v + v − v (2475) dt 556 861 862 541

Produced by SBML2LATEX 971 7.426 Species M iacgam c

Name 1D-myo-inositol 2-Acetamido-2-deoxy-D-glucopyranoside

Charge 0

This species takes part in two reactions (as a reactant in R IGAMD and as a product in R IACGAMS).

d M iacgam c = v − v (2476) dt 542 548

7.427 Species M iasp c

Name Iminoaspartate

Charge -2

This species takes part in two reactions (as a reactant in R QULNS and as a product in R ASPO5).

d M iasp c = v − v (2477) dt 112 871

7.428 Species M ichor c

Name Isochorismate

Charge -2

This species takes part in three reactions (as a reactant in R SHCHCS, R SHCHCS2 and as a product in R ICHORSi).

d M ichor c = v − v − v (2478) dt 544 905 906

7.429 Species M icit c

Name Isocitrate

Charge -3

This species takes part in three reactions (as a reactant in R ICDHy, R ICL and as a product in R ACONT).

d M icit c = v − v − v (2479) dt 24 543 545

972 Produced by SBML2LATEX 7.430 Species M id3acald c

Name Indole-3-acetaldehyde

Charge 0

This species takes part in two reactions (as a reactant in R ID3ACALDt and as a product in R- INDPYRD).

d M id3acald c = v − v (2480) dt 555 546

7.431 Species M id3acald e

Name Indole-3-acetaldehyde

Charge 0

This species takes part in two reactions (as a reactant in R EX id3acald e and as a product in R ID3ACALDt).

d M id3acald e = v − v (2481) dt 546 298

7.432 Species M idp c

Name IDP

Charge -3

This species takes part in two reactions (as a reactant in R NDPK9 and as a product in R ADK4).

d M idp c = v − v (2482) dt 40 684

7.433 Species M igam c

Name 1D-myo-inositol 2-deoxy-D-glucopyranoside

Charge 1

This species takes part in three reactions (as a reactant in R CIGAMS and as a product in R IGAMD, R MSHAMID).

d M igam c = v + v − v (2483) dt 548 631 145

Produced by SBML2LATEX 973 7.434 Species M ile DASH L c

Name L-Isoleucine

Charge 0

This species takes part in three reactions (as a reactant in R ILETA, R biomass Mtb 9 60atp and as a product in R ILEt2r).

d M ile DASH L c = v − v − 0.087731v (2484) dt 552 551 1025

7.435 Species M ile DASH L e

Name L-Isoleucine

Charge 0

This species takes part in two reactions (as a reactant in R EX ile DASH L e, R ILEt2r).

d M ile DASH L e = −v − v (2485) dt 299 552

7.436 Species M imacp c

Name 3-(Imidazol-4-yl)-2-oxopropyl phosphate

Charge -2

This species takes part in two reactions (as a reactant in R HSTPT and as a product in R IGPDH).

d M imacp c = v − v (2486) dt 549 540

7.437 Species M imp c

Name IMP

Charge -2

This species takes part in six reactions (as a reactant in R ADSS, R IMPC, R IMPD, R NTD11 and as a product in R HXPRT, R INSK).

d M imp c = v + v − v − v − v − v (2487) dt 541 557 52 553 554 699

974 Produced by SBML2LATEX 7.438 Species M indole c

Name Indole

Charge 0

This species takes part in two reactions (as a reactant in R TRPS2 and as a product in R TRPS3).

d M indole c = v − v (2488) dt 975 974

7.439 Species M indpyr c

Name Indolepyruvate

Charge -1

This species takes part in two reactions (as a reactant in R INDPYRD and as a product in R TRPTA).

d M indpyr c = v − v (2489) dt 976 555

7.440 Species M inost c

Name myo-Inositol

Charge 0

This species takes part in ﬁve reactions (as a reactant in R CDPPT160, R CDPPT160190 and as a product in R MI1PP, R MI3PP, R MI4PP).

d M inost c = v + v + v − v − v (2490) dt 614 616 617 138 139

7.441 Species M ins c

Name Inosine

Charge 0

This species takes part in ﬁve reactions (as a reactant in R INSH, R INSK, R PUNP5 and as a product in R ADA, R NTD11).

d M ins c = v + v − v − v − v (2491) dt 31 699 556 557 861

Produced by SBML2LATEX 975 7.442 Species M ipdp c

Name Isopentenyl diphosphate

Charge -3

This species takes part in ten reactions (as a reactant in R DCPDPS, R DMATT, R DPPS, R GRTT, R IPDDI, R OCTDPS, R UDCPDPS, R UDPDPS, R UDPDPS2 and as a product in R IPDPS).

d M ipdp c = v − 7v − v − 7v − v − v − 5v − 8v − v − v (2492) dt 559 205 236 242 500 558 724 995 996 997

7.443 Species M itp c

Name ITP

Charge -4

This species takes part in two reactions (as a reactant in R ADK4 and as a product in R NDPK9).

d M itp c = v − v (2493) dt 684 40

7.444 Species M k c

Name potassium

Charge 1

This species takes part in three reactions (as a reactant in R Kt3r, R NAKtr and as a product in R Kabc).

d M k c = v − v − v (2494) dt 566 567 672

7.445 Species M k e

Name potassium

Charge 1

This species takes part in four reactions (as a reactant in R EX k e, R Kabc and as a product in R Kt3r, R NAKtr).

d M k e = v + v − v − v (2495) dt 567 672 300 566

976 Produced by SBML2LATEX 7.446 Species M kmeroacidACP c

Name keto meroacid ACP

Charge -1

This species takes part in three reactions (as a reactant in R MYC1CYC3, R MYC1M2 and as a product in R MYCSacp58).

d M kmeroacidACP c = v − v − v (2496) dt 662 642 646

7.447 Species M kmeroacidcyc1ACP c

Name cyclopropanated keto-meroacid ACP (1 cyclopropane ring)

Charge -1

This species takes part in two reactions (as a reactant in R MYC2CYC3 and as a product in R- MYC1CYC3).

d M kmeroacidcyc1ACP c = v − v (2497) dt 642 649

7.448 Species M kmeroacidcyc2ACP c

Name cyclopropanated keto-meroacid ACP (2 cyclopropane rings)

Charge -1

This species takes part in two reactions (as a reactant in R FAMPL3 and as a product in R- MYC2CYC3).

d M kmeroacidcyc2ACP c = v − v (2498) dt 649 358

7.449 Species M kmeroacidcyc2AMP c

Name cyclopropanated keto-meroacid AMP (2 cyclopropane rings)

Charge -1

This species takes part in two reactions (as a reactant in R MYCON3 and as a product in R FAMPL3).

d M kmeroacidcyc2AMP c = v − v (2499) dt 358 657

Produced by SBML2LATEX 977 7.450 Species M kmycolate c

Name keto mycolate (2 cyclopropanated rings)

Charge -1

This species takes part in four reactions (as a reactant in R MYCFLUX3, R TDMS4, R biomass- Mtb 9 60atp and as a product in R MYCON3).

d M kmycolate c = v − v − v − 0.003338v (2500) dt 657 652 938 1025

7.451 Species M lac DASH L c

Name L-Lactate

Charge -1

This species takes part in seven reactions (as a reactant in R LDH L, R LO, R L LACD, R L LACD2, R L LACD3, R L LACt3 and as a product in R L LACt2r).

d M lac DASH L c = v − v − v − v − v − v − v (2501) dt 580 570 573 577 578 579 581

7.452 Species M lac DASH L e

Name L-Lactate

Charge -1

This species takes part in three reactions (as a reactant in R EX lac DASH L e, R L LACt2r and as a product in R L LACt3).

d M lac DASH L e = v − v − v (2502) dt 581 301 580

7.453 Species M lald DASH L c

Name L-Lactaldehyde

Charge 0

This species takes part in one reaction (as a product in R FCLPA).

d M lald DASH L c = v (2503) dt 401

978 Produced by SBML2LATEX 7.454 Species M lcts c

Name Lactose

Charge 0

This species takes part in two reactions (as a reactant in R LACZ and as a product in R LCTSabc).

d M lcts c = v − v (2504) dt 569 568

7.455 Species M lcts e

Name Lactose

Charge 0

This species takes part in two reactions (as a reactant in R EX lcts e, R LCTSabc).

d M lcts e = −v − v (2505) dt 302 569

7.456 Species M leu DASH L c

Name L-Leucine

Charge 0

This species takes part in three reactions (as a reactant in R LEUTA, R biomass Mtb 9 60atp and as a product in R LEUt2r).

d M leu DASH L c = v − v − 0.204706v (2506) dt 572 571 1025

7.457 Species M leu DASH L e

Name L-Leucine

Charge 0

This species takes part in two reactions (as a reactant in R EX leu DASH L e, R LEUt2r).

d M leu DASH L e = −v − v (2507) dt 303 572

Produced by SBML2LATEX 979 7.458 Species M lpam c

Name Lipoamide

Charge 0

This species takes part in three reactions (as a reactant in R PDHa and as a product in R PDHc, R PDHcr).

d M lpam c = v + v − v (2508) dt 760 761 758

7.459 Species M lpro c

Name Lipoylprotein

Charge 0

This species takes part in two reactions (as a reactant in R GCCa and as a product in R GCCc).

d M lpro c = v − v (2509) dt 459 457

7.460 Species M lys DASH L c

Name L-Lysine

Charge 1

This species takes part in eight reactions (as a reactant in R MCBTS, R MCBTS2, R MCBTS3, R- UAAGLS1, R UAAGLS2, R biomass Mtb 9 60atp and as a product in R DAPDC, R LYSt5r).

d M lys DASH L c = v + v − 2v − 2v − 2v − v − v − 0.03909v (2510) dt 195 576 593 594 595 983 984 1025

7.461 Species M lys DASH L e

Name L-Lysine

Charge 1

This species takes part in two reactions (as a reactant in R EX lys DASH L e, R LYSt5r).

d M lys DASH L e = −v − v (2511) dt 304 576

980 Produced by SBML2LATEX 7.462 Species M m1ocdca c

Name methyl octadecanoate

Charge -1

This species takes part in two reactions (as a reactant in R FASm1801 and as a product in R- FASm1601).

d M m1ocdca c = v − v (2512) dt 378 380

7.463 Species M malACP c

Name Malonyl-[acyl-carrier protein]

Charge -2

This species takes part in ﬁve reactions (as a reactant in R FASPHDCA, R MYCSacp50, R MYCSacp56, R MYCSacp58 and as a product in R MCOATA).

d M malACP c = v − 8v − 12v − 15v − 16v (2513) dt 597 377 660 661 662

7.464 Species M mal DASH L c

Name L-Malate

Charge -2

This species takes part in ﬁve reactions (as a reactant in R MDH, R ME1 and as a product in R FUM, R MALS, R MALt2r).

d M mal DASH L c = v + v + v − v − v (2514) dt 428 582 586 599 600

7.465 Species M mal DASH L e

Name L-Malate

Charge -2

This species takes part in two reactions (as a reactant in R EX mal DASH L e, R MALt2r).

d M mal DASH L e = −v − v (2515) dt 305 586

Produced by SBML2LATEX 981 7.466 Species M malcoa c

Name Malonyl-CoA

Charge -5

This species takes part in 17 reactions (as a reactant in R FAS100, R FAS120, R FAS140, R- FAS160, R FAS161, R FAS180, R FAS181, R FAS200, R FAS240 L, R FAS260, R FAS80 L, R- FASm180, R MCD, R MCOATA, R PREPTHS, R PREPTHS2 and as a product in R ACCOACr).

d M malcoa c = v − v − v − v − v − v − v − v − v dt 14 366 367 368 369 370 371 372 373 (2516) − 3v374 − v375 − 3v376 − 4v379 − v596 − v597 − 2v839 − 2v840

7.467 Species M malt c

Name Maltose

Charge 0

This species takes part in three reactions (as a reactant in R MALT and as a product in R MALTabc, R MTI). d M malt c = v + v − v (2517) dt 585 639 583

7.468 Species M malt e

Name Maltose

Charge 0

This species takes part in two reactions (as a reactant in R EX malt e, R MALTabc).

d M malt e = −v − v (2518) dt 306 585

7.469 Species M malthp c

Name Maltoheptaose

Charge 0

This species takes part in two reactions (as a reactant in R MOTS and as a product in R MALTHPabc).

d M malthp c = v − v (2519) dt 584 629

982 Produced by SBML2LATEX 7.470 Species M malthp e

Name Maltoheptaose

Charge 0

This species takes part in two reactions (as a reactant in R EX malthp e, R MALTHPabc).

d M malthp e = −v − v (2520) dt 307 584

7.471 Species M maltpt c

Name Maltopentaose

Charge 0

This species takes part in one reaction (as a product in R MOTH).

d M maltpt c = v (2521) dt 628

7.472 Species M man1p c

Name D-Mannose 1-phosphate

Charge -2

This species takes part in three reactions (as a reactant in R MAN1PT, R MAN1PT2, R PMANM).

d M man1p c = −v − v − v (2522) dt 587 588 804

7.473 Species M man6p c

Name D-Mannose 6-phosphate

Charge -2

This species takes part in three reactions (as a reactant in R MAN6PI, R MN6PP and as a product in R PMANM).

d M man6p c = v − v − v (2523) dt 804 589 624

Produced by SBML2LATEX 983 7.474 Species M man c

Name D-Mannose

Charge 0

This species takes part in two reactions (as a reactant in R biomass Mtb 9 60atp and as a product in R MN6PP).

d M man c = v − 0.095065v (2524) dt 624 1025

7.475 Species M marach c

Name methyl arachidic acid

Charge -1

This species takes part in two reactions (as a reactant in R FASm2202 and as a product in R- FASm2002).

d M marach c = v − v (2525) dt 382 385

7.476 Species M mbhn c

Name methyl behenic acid

Charge -1

This species takes part in three reactions (as a reactant in R FASm240, R biomass Mtb 9 60atp and as a product in R FASm220).

d M mbhn c = v − v − 0.00784v (2526) dt 383 386 1025

7.477 Species M mcbts c

Name mycobactin S

Charge 2

This species takes part in two reactions (as a reactant in R biomass Mtb 9 60atp and as a product in R MCBTS).

d M mcbts c = v − 0.001402v (2527) dt 593 1025

984 Produced by SBML2LATEX 7.478 Species M mcbtt c

Name mycobactin T

Charge 2

This species takes part in four reactions (as a product in R FCLT2, R FETRANS, R MCBTS2, R- SHCHF3).

d M mcbtt c = v + v + v + v (2528) dt 403 409 594 911

7.479 Species M meoh c

Name Methanol

Charge 0

This species takes part in two reactions (as a reactant in R PRDX and as a product in R MEOHt2).

d M meoh c = v − v (2529) dt 603 836

7.480 Species M meoh e

Name Methanol

Charge 0

This species takes part in two reactions (as a reactant in R EX meoh e, R MEOHt2).

d M meoh e = −v − v (2530) dt 308 603

7.481 Species M meroacidACP c

Name alpha meroacid ACP

Charge -1

This species takes part in two reactions (as a reactant in R MYC1CYC1 and as a product in R- MYCSacp50).

d M meroacidACP c = v − v (2531) dt 660 640

Produced by SBML2LATEX 985 7.482 Species M meroacidcyc1ACP c

Name cyclopropanated alpha meroacid ACP (1 cyclopropane ring)

Charge -1

This species takes part in two reactions (as a reactant in R MYC2CYC1 and as a product in R- MYC1CYC1). d M meroacidcyc1ACP c = v − v (2532) dt 640 647

7.483 Species M meroacidcyc2ACP c

Name cyclopropanated alpha meroacid ACP (2 cyclopropane rings)

Charge -1

This species takes part in two reactions (as a reactant in R FAMPL1 and as a product in R- MYC2CYC1). d M meroacidcyc2ACP c = v − v (2533) dt 647 356

7.484 Species M meroacidcyc2AMP c

Name cyclopropanated alpha meroacid AMP (2 cyclopropane rings)

Charge -1

This species takes part in two reactions (as a reactant in R MYCON1 and as a product in R FAMPL1). d M meroacidcyc2AMP c = v − v (2534) dt 356 655

7.485 Species M met DASH L c

Name L-Methionine

Charge 0

This species takes part in ten reactions (as a reactant in R METAT, R METOX1s, R METOX2s, R- biomass Mtb 9 60atp and as a product in R HCYSMT, R METS, R METSOXR1, R METSOXR2, R METabc, R MHPGLUT).

d M met DASH L c = v + v + v + v + v + v dt 521 608 609 610 611 613 (2535) − v605 − v606 − v607 − 0.034889v1025

986 Produced by SBML2LATEX 7.486 Species M met DASH L e

Name L-Methionine

Charge 0

This species takes part in two reactions (as a reactant in R EX met DASH L e, R METabc).

d M met DASH L e = −v − v (2536) dt 309 611

7.487 Species M methf c

Name 5,10-Methenyltetrahydrofolate

Charge -1

This species takes part in ﬁve reactions (as a reactant in R MTHFC and as a product in R FOMETR, R FTHFCL, R MTHFD, R MTHFD2).

d M methf c = v + v + v + v − v (2537) dt 415 425 636 637 635

7.488 Species M metsox DASH R DASH L c

Name L-methionine-R-sulfoxide

Charge 0

This species takes part in two reactions (as a reactant in R METSOXR2 and as a product in R- METOX2s).

d M metsox DASH R DASH L c = v − v (2538) dt 607 610

7.489 Species M metsox DASH S DASH L c

Name L-Methionine Sulfoxide

Charge 0

This species takes part in two reactions (as a reactant in R METSOXR1 and as a product in R- METOX1s).

d M metsox DASH S DASH L c = v − v (2539) dt 606 609

Produced by SBML2LATEX 987 7.490 Species M mettrna c Name L-Methionyl-tRNA (Met)

Charge 1 This species takes part in one reaction (as a reactant in R FMETTRS). d M mettrna c = −v (2540) dt 411

7.491 Species M mfrrppdima c Name phenolic glycolipid (Mtb)

Charge 0 This species takes part in two reactions (as a reactant in R biomass Mtb 9 60atp and as a product in R PGLS). d M mfrrppdima c = v − 0.001184v (2541) dt 775 1025

7.492 Species M mg2 c Name magnesium

Charge 2 This species takes part in two reactions (as a reactant in R MGt5, R MPML). d M mg2 c = −v − v (2542) dt 612 630

7.493 Species M mg2 e Name magnesium

Charge 2 This species takes part in two reactions (as a reactant in R EX mg2 e and as a product in R MGt5). d M mg2 e = v − v (2543) dt 612 310

7.494 Species M mharab DASH D c Name mannose capped hexa arabinofuranoside

Charge 0 This species takes part in two reactions (as a reactant in R ARABF and as a product in R GMT2). d M mharab DASH D c = v − 8v (2544) dt 497 91

988 Produced by SBML2LATEX 7.495 Species M mhpglu c

Name 5-Methyltetrahydropteroyltri-L-glutamate

Charge 0

This species takes part in one reaction (as a reactant in R MHPGLUT).

d M mhpglu c = −v (2545) dt 613

7.496 Species M mi1p DASH D c

Name 1D-myo-Inositol 1-phosphate

Charge -2

This species takes part in four reactions (as a reactant in R IACGAMS, R MI1PP and as a product in R MI1PS, R PLCD).

d M mi1p DASH D c = v + v − v − v (2546) dt 615 801 542 614

7.497 Species M mi3p DASH D c

Name 1D-myo-Inositol 3-phosphate

Charge -2

This species takes part in one reaction (as a reactant in R MI3PP).

d M mi3p DASH D c = −v (2547) dt 616

7.498 Species M mi4p DASH D c

Name 1D-myo-Inositol 4-phosphate

Charge -2

This species takes part in one reaction (as a reactant in R MI4PP).

d M mi4p DASH D c = −v (2548) dt 617

Produced by SBML2LATEX 989 7.499 Species M mkmeroacidACP c

Name methyl hydroxy keto meroacid ACP (1 cyclopropane ring)

Charge -1

This species takes part in two reactions (as a reactant in R MYC1CYC5 and as a product in R- MYC1M2).

d M mkmeroacidACP c = v − v (2549) dt 646 644

7.500 Species M mkmeroacidcyc1ACP c

Name cyclopropanated methyl hydroxy keto meroacid ACP (1 cyclopropane ring)

Charge -1

This species takes part in two reactions (as a reactant in R FAMPL5 and as a product in R- MYC1CYC5).

d M mkmeroacidcyc1ACP c = v − v (2550) dt 644 360

7.501 Species M mkmeroacidcyc1AMP c

Name cyclopropanated methyl hydroxy keto meroacid AMP (1 cyclopropane ring)

Charge -1

This species takes part in two reactions (as a reactant in R MYCON5 and as a product in R FAMPL5).

d M mkmeroacidcyc1AMP c = v − v (2551) dt 360 659

7.502 Species M mkmycolate c

Name keto mycolate (1 cyclopropanated rings)

Charge -1

This species takes part in four reactions (as a reactant in R MYCFLUX5, R TDMS3, R biomass- Mtb 9 60atp and as a product in R MYCON5).

d M mkmycolate c = v − v − v − 0.003291v (2552) dt 659 654 937 1025

990 Produced by SBML2LATEX 7.503 Species M mlthf c Name 5,10-Methylenetetrahydrofolate

Charge -2 This species takes part in nine reactions (as a reactant in R MOHMT, R MTHFD, R MTHFD2, R- MTHFR2, R TMDS and as a product in R GCC2, R GCCb, R GHMT2, R GLYCL). d M mlthf c = v + v + v + v − v − v − v − v − v (2553) dt 456 458 463 486 627 636 637 638 956

7.504 Species M mmcoa DASH R c Name (R)-Methylmalonyl-CoA

Charge -5 This species takes part in two reactions (as a reactant in R MME and as a product in R MMM2r). d M mmcoa DASH R c = v − v (2554) dt 620 619

7.505 Species M mmcoa DASH S c Name (S)-Methylmalonyl-CoA

Charge -5 This species takes part in 26 reactions (as a reactant in R FASm1601, R FASm180, R FASm1801, R FASm2001, R FASm2002, R FASm220, R FASm2201, R FASm2202, R FASm240, R FASm2401, R FASm2402, R FASm260, R FASm2601, R FASm2602, R FASm280, R FASm2801, R FASm2802, R FASm300, R FASm3001, R FASm320, R FASm340, R MMCD, R PREPTHS, R PREPTHS2 and as a product in R MME, R PPCOAC). d M mmcoa DASH S c = v + v − v − v − v − v − v − v − v dt 619 814 378 379 380 381 382 383 384 − v385 − v386 − v387 − v388 − v389 − v390 − v391 − v392 − v393 − v394 − v395 − v396 − v397 − v398 − v618 − 2v839 − 2v840 (2555)

7.506 Species M mmeroacidACP c Name methoxy meroacid ACP

Charge -1 This species takes part in three reactions (as a reactant in R MYC1CYC2, R MYC1M1 and as a product in R MYCSacp56). d M mmeroacidACP c = v − v − v (2556) dt 661 641 645

Produced by SBML2LATEX 991 7.507 Species M mmeroacidcyc1ACP c

Name cyclopropanated methoxy-meroacid ACP (1 cyclopropane ring)

Charge -1

This species takes part in two reactions (as a reactant in R MYC2CYC2 and as a product in R- MYC1CYC2).

d M mmeroacidcyc1ACP c = v − v (2557) dt 641 648

7.508 Species M mmeroacidcyc2ACP c

Name cyclopropanated methoxy-meroacid ACP (2 cyclopropane rings)

Charge -1

This species takes part in two reactions (as a reactant in R FAMPL2 and as a product in R- MYC2CYC2).

d M mmeroacidcyc2ACP c = v − v (2558) dt 648 357

7.509 Species M mmeroacidcyc2AMP c

Name cyclopropanated methoxy-meroacid AMP (2 cyclopropane rings)

Charge -1

This species takes part in two reactions (as a reactant in R MYCON2 and as a product in R FAMPL2).

d M mmeroacidcyc2AMP c = v − v (2559) dt 357 656

7.510 Species M mmmeroacidACP c

Name methyl hydroxy methoxy meroacid ACP

Charge -1

This species takes part in two reactions (as a reactant in R MYC1CYC4 and as a product in R- MYC1M1).

d M mmmeroacidACP c = v − v (2560) dt 645 643

992 Produced by SBML2LATEX 7.511 Species M mmmeroacidcyc1ACP c

Name cyclopropanated methyl hydroxy methoxy meroacid ACP (1 cyclopropane ring)

Charge -1

This species takes part in two reactions (as a reactant in R FAMPL4 and as a product in R- MYC1CYC4).

d M mmmeroacidcyc1ACP c = v − v (2561) dt 643 359

7.512 Species M mmmeroacidcyc1AMP c

Name cyclopropanated methyl hydroxy methoxy meroacid AMP (1 cyclopropane ring)

Charge -1

This species takes part in two reactions (as a reactant in R MYCON4 and as a product in R FAMPL4).

d M mmmeroacidcyc1AMP c = v − v (2562) dt 359 658

7.513 Species M mmmycolate c

Name methoxy mycolate (1 cyclopropanated ring)

Charge -1

This species takes part in four reactions (as a reactant in R MYCFLUX4, R TDMS2, R biomass- Mtb 9 60atp and as a product in R MYCON4).

d M mmmycolate c = v − v − v − 0.003365v (2563) dt 658 653 936 1025

7.514 Species M mmycolate c

Name methoxy mycolate (2 cyclopropanated rings)

Charge -1

This species takes part in three reactions (as a reactant in R MYCFLUX2, R TDMS1 and as a product in R MYCON2).

d M mmycolate c = v − v − v (2564) dt 656 651 935

Produced by SBML2LATEX 993 7.515 Species M mndn c

Name menadione

Charge 0

This species takes part in three reactions (as a reactant in R PHTHCLS and as a product in R- MNDNS1, R MNDNS2).

d M mndn c = v + v − v (2565) dt 625 626 792

7.516 Species M mocdca c

Name 10-methylstearic acid

Charge -1

This species takes part in three reactions (as a reactant in R AACPS10, R biomass Mtb 9 60atp and as a product in R FASm180).

d M mocdca c = v − v − 0.095802v (2566) dt 379 5 1025

7.517 Species M motre c

Name maltooligosyltrehalose

Charge 0

This species takes part in two reactions (as a reactant in R MOTH and as a product in R MOTS).

d M motre c = v − v (2567) dt 629 628

7.518 Species M mppp9 c

Name Magnesium protoporphyrin

Charge -2

This species takes part in one reaction (as a product in R MPML).

d M mppp9 c = v (2568) dt 630

994 Produced by SBML2LATEX 7.519 Species M mql6 c

Name Menaquinol 6

Charge 0

This species takes part in two reactions (as a reactant in R FRD5 and as a product in R DHORD3).

d M mql6 c = v − v (2569) dt 228 420

7.520 Species M mql8 c

Name Menaquinol 8

Charge 0

This species takes part in eight reactions (as a reactant in R CYTBD2, R FRD2, R NO3R2 and as a product in R AMMQT8, R DHORD5, R GLYCTO3, R L LACD3, R NADH10).

d M mql8 c = v + v + v + v + v − v − v − v (2570) dt 83 229 489 579 665 181 418 693

7.521 Species M mqn6 c

Name Menaquinone 6

Charge 0

This species takes part in three reactions (as a reactant in R DHORD3 and as a product in R- AMMQT6, R FRD5).

d M mqn6 c = v + v − v (2571) dt 82 420 228

7.522 Species M mqn8 c

Name Menaquinone 8

Charge 0

This species takes part in eight reactions (as a reactant in R DHORD5, R GLYCTO3, R L LACD3, R NADH10 and as a product in R AMMQT8 2, R CYTBD2, R FRD2, R NO3R2).

d M mqn8 c = v + v + v + v − v − v − v − v (2572) dt 84 181 418 693 229 489 579 665

Produced by SBML2LATEX 995 7.523 Species M msa c Name Malonate semialdehyde

Charge -1 This species takes part in two reactions (as a reactant in R MMSAD3 and as a product in R APATr). d M msa c = v − v (2573) dt 89 623

7.524 Species M msh c Name mycothiol (reduced)

Charge 0 This species takes part in ﬁve reactions (as a reactant in R BMNMSHS, R MYCTR, R MYCTR2 and as a product in R MSHOXH, R MSHS). d M msh c = v + v − v − 2v − 2v (2574) dt 632 633 123 663 664

7.525 Species M mshfald c Name mycothiol conjugated methanol

Charge 0 This species takes part in one reaction (as a reactant in R MDFDH). d M mshfald c = −v (2575) dt 598

7.526 Species M mshfaldox c Name mycothiol conjugated aldehyde

Charge 0 This species takes part in two reactions (as a reactant in R MSHOXH and as a product in R MDFDH). d M mshfaldox c = v − v (2576) dt 598 632

7.527 Species M mssg c Name mycothiol (oxidized - dimer)

Charge 0 This species takes part in two reactions (as a product in R MYCTR, R MYCTR2). d M mssg c = v + v (2577) dt 663 664

996 Produced by SBML2LATEX 7.528 Species M mstrACP c

Name 10methyl stearyoyl-ACP

Charge -1

This species takes part in four reactions (as a reactant in R AGPAT160190, R AGPAT190, R- G3PAT190 and as a product in R AACPS10).

d M mstrACP c = v − v − v − v (2578) dt 5 58 59 443

7.529 Species M mycolate c

Name mycolate (2 cyclopropanated rings)

Charge -1

This species takes part in seven reactions (as a reactant in R MYCFLUX1, R TDMS1, R TDMS2, R TDMS3, R TDMS4, R biomass Mtb 9 60atp and as a product in R MYCON1).

d M mycolate c = v − v − v − v − v − v − 0.011003v (2579) dt 655 650 935 936 937 938 1025

7.530 Species M na1 c

Name Sodium

Charge 1

This species takes part in two reactions (as a reactant in R NAt3 1 and as a product in R NAKtr).

d M na1 c = v − v (2580) dt 672 675

7.531 Species M na1 e

Name Sodium

Charge 1

This species takes part in three reactions (as a reactant in R EX na1 e, R NAKtr and as a product in R NAt3 1).

d M na1 e = v − v − v (2581) dt 675 311 672

Produced by SBML2LATEX 997 7.532 Species M nac c Name Nicotinate

Charge -1

This species takes part in three reactions (as a reactant in R NAPRTr and as a product in R NNAM, R NNDMBRT). d M nac c = v + v − v (2582) dt 687 689 673

7.533 Species M nad c Name Nicotinamide adenine dinucleotide

Charge -1

This species takes part in 65 reactions (as a reactant in R ACALDi, R ALAD L, R ALDD1, R- ALDD19x, R ALDD2x, R BDH, R BETALDHx, R CHOLD, R DGC3D, R E4PD, R FAO1, R FAO10, R- FAO11, R FAO2, R FAO3, R FDH, R FRDO3r, R G3PD1, R GAPD, R GCCc, R GLUDx, R GLXO1, R GLYCL, R HISTD, R HSDx, R IMPD, R IPMD, R LDH L, R MDFDH, R MDH, R ME1, R MMSAD1, R MMSAD2, R MMSAD3, R MTHFD2, R NADK, R NADTRHD, R P5CD, R PDH, R PDHc, R PDHcr, R- PERD, R PGCD, R PHTHCLR1, R PPND, R SGSAD, R SHCHD2, R SHCHD3, R SSALx, R THD1, R- UDPGD and as a product in R CYRDAR, R DMPPS, R G5SD2, R IPDPS, R MNDNS2, R MTHFR2, R NADH10, R NADH2r, R NADH5, R NADH9, R NADS2, R NTRIR2x, R NTRIRx, R P5CRx). d M nad c = v + v + v + v + 2v + v + v + v + v + v + v dt 175 237 447 559 626 638 665 666 667 668 670 + 3v716 + 3v717 + v739 − v11 − v72 − v77 − v78 − v79 − v121 − v122 − v141 − v215 − v252 − 6v361 − 8v362 − 7v363 − 7v364 − 8v365 − v405 − 2v422 − v444 − v454 − v459 − v476 − v482 − v486 − 2v524 − v535 − v554 − v560 − v570 − v598 − v599 − v600 − v621 − v622 − v623 − v637 − v669 − v671 − v737 − v757 − v760 − v761 − v767 − v771 − v790 − v824 − v904 − v907 − v908 − v920 − v942 − 2v1000 (2583)

7.534 Species M nadh c Name Nicotinamide adenine dinucleotide - reduced

Charge -2

This species takes part in 63 reactions (as a reactant in R CYRDAR, R DMPPS, R G5SD2, R IPDPS, R MNDNS2, R MTHFR2, R NADH10, R NADH2r, R NADH5, R NADH9, R NTRIR2x, R NTRIRx, R- P5CRx and as a product in R ACALDi, R ALAD L, R ALDD1, R ALDD19x, R ALDD2x, R BDH, R- BETALDHx, R CHOLD, R DGC3D, R E4PD, R FAO1, R FAO10, R FAO11, R FAO2, R FAO3, R FDH, R FRDO3r, R G3PD1, R GAPD, R GCCc, R GLUDx, R GLXO1, R GLYCL, R HISTD, R HSDx, R IMPD,

998 Produced by SBML2LATEX R IPMD, R LDH L, R MDFDH, R MDH, R ME1, R MMSAD1, R MMSAD2, R MMSAD3, R MTHFD2, R- NADTRHD, R P5CD, R PDH, R PDHc, R PDHcr, R PERD, R PGCD, R PHTHCLR1, R PPND, R SGSAD, R SHCHD2, R SHCHD3, R SSALx, R THD1, R UDPGD).

d M nadh c = v + v + v + v + v + v + v + v + v + v + 6v dt 11 72 77 78 79 121 122 141 215 252 361 + 8v362 + 7v363 + 7v364 + 8v365 + v405 + 2v422 + v444 + v454 + v459 + v476 + v482 + v486 + 2v524 + v535 + v554 + v560 + v570 + v598 + v599 + v600 + v621 + v622 + v623 + v637 + v671 + v737 + v757 + v760 + v761 + v767 + v771 + v790 + v824 + v904 + v907 + v908 + v920 + v942 + 2v1000 − v175 − v237 − v447 − v559 − 2v626 − v638 − v665 − v666 − v667 − v668 − 3v716 − 3v717 − v739 (2584)

7.535 Species M nadp c

Name Nicotinamide adenine dinucleotide phosphate

Charge -3

This species takes part in 86 reactions (as a reactant in R AGPR, R ASAD, R FRDO2r, R FRDOr, R G6PDH2, R GND, R HSDy, R ICDHy, R MCBTS3, R MTHFD, R MYCTR, R PHTHCLR2, R SSALy, R- SULR and as a product in R 5DGLCNR, R APRAUR, R CPC6R, R DESAT16, R DESAT18, R DHDPRy, R DHFR, R DPR, R DXPRIi, R FAH4, R FAS100, R FAS120, R FAS140, R FAS160, R FAS161, R- FAS180, R FAS181, R FAS200, R FAS240 L, R FAS260, R FAS80 L, R FASPHDCA, R FASm1601, R FASm180, R FASm1801, R FASm2001, R FASm2002, R FASm220, R FASm2201, R FASm2202, R FASm240, R FASm2401, R FASm2402, R FASm260, R FASm2601, R FASm2602, R FASm280, R FASm2801, R FASm2802, R FASm300, R FASm3001, R FASm320, R FASm340, R FOLR2, R- G5SD, R GFUCS, R GLUSy, R GLUTRR, R GTHOr, R KARA1i, R KARA2i, R MNDNS1, R MYCSacp50, R MYCSacp56, R MYCSacp58, R NADK, R NADTRHD, R NTRIRy, R P5CR, R PC6AR, R PHTHCLS, R PHTHS, R PHTHS2, R PREPTHS, R PREPTHS2, R QRr, R SHK3Dr, R TDPDRR, R THD1, R TRDR, R UAMRH, R UAPGR).

d M nadp c = v + v + v + v + v + v + v + v + v + v + 2v + 2v dt 4 90 164 213 214 219 221 243 250 355 366 367 + 2v368 + 2v369 + 3v370 + 2v371 + 3v372 + 2v373 + 6v374 + 2v375 + 6v376 + 16v377 + 2v378 + 10v379 + 2v380 + 2v381 + 2v382 + 2v383 + 2v384 + 2v385 + 2v386 + 2v387 + 2v388 + 2v389 + 2v390 + 2v391 + 2v392 + 2v393 + 2v394 + 2v395 + 2v396 + 2v397 + 2v398 + v414 + v446 + v461 + v479 + v480 + v502 + v564 + v565 + 2v625 + 24v660 +30v661 +30v662 +v669 +v671 +3v718 +v738 +v752 +v792 +v795 +v796 +10v839 + 10v840 + v870 + v912 + v940 + v942 + v967 + v992 + v993 − v60 − v104 − 2v421 − v423 − v448 − v498 − v536 − v543 − 2v595 − v636 − v663 − v791 − v921 − 3v927 (2585)

Produced by SBML2LATEX 999 7.536 Species M nadph c

Name Nicotinamide adenine dinucleotide phosphate - reduced

Charge -4

This species takes part in 85 reactions (as a reactant in R 5DGLCNR, R APRAUR, R CPC6R, R- DESAT16, R DESAT18, R DHDPRy, R DHFR, R DPR, R DXPRIi, R FAH4, R FAS100, R FAS120, R FAS140, R FAS160, R FAS161, R FAS180, R FAS181, R FAS200, R FAS240 L, R FAS260, R FAS80 L, R FASPHDCA, R FASm1601, R FASm180, R FASm1801, R FASm2001, R FASm2002, R FASm220, R FASm2201, R FASm2202, R FASm240, R FASm2401, R FASm2402, R FASm260, R FASm2601, R FASm2602, R FASm280, R FASm2801, R FASm2802, R FASm300, R FASm3001, R FASm320, R FASm340, R FOLR2, R G5SD, R GFUCS, R GLUSy, R GLUTRR, R GTHOr, R KARA1i, R KARA2i, R MNDNS1, R MYCSacp50, R MYCSacp56, R MYCSacp58, R NADTRHD, R NTRIRy, R- P5CR, R PC6AR, R PHTHCLS, R PHTHS, R PHTHS2, R PREPTHS, R PREPTHS2, R QRr, R SHK3Dr, R TDPDRR, R THD1, R TRDR, R UAMRH, R UAPGR and as a product in R AGPR, R ASAD, R FRDO2r, R FRDOr, R G6PDH2, R GND, R HSDy, R ICDHy, R MCBTS3, R MTHFD, R MYCTR, R PHTHCLR2, R SSALy, R SULR). d M nadph c = v + v + 2v + v + v + v + v + v + 2v + v + v + v dt 60 104 421 423 448 498 536 543 595 636 663 791 + v921 + 3v927 − v4 − v90 − v164 − v213 − v214 − v219 − v221 − v243 − v250 − v355 − 2v366 − 2v367 − 2v368 − 2v369 − 3v370 − 2v371 − 3v372 − 2v373 − 6v374 − 2v375 − 6v376 − 16v377 − 2v378 − 10v379 − 2v380 − 2v381 − 2v382 − 2v383 − 2v384 − 2v385 − 2v386 − 2v387 − 2v388 − 2v389 − 2v390 − 2v391 − 2v392 − 2v393 − 2v394 − 2v395 − 2v396 − 2v397 − 2v398 − v414 − v446 − v461 − v479 − v480 − v502 − v564 − v565 − 2v625 − 24v660 − 30v661 − 30v662 − v671 − 3v718 − v738 − v752 − v792 − v795 − v796 − 10v839 − 10v840 − v870 − v912 − v940 − v942 − v967 − v992 − v993 (2586)

7.537 Species M ncam c

Name Nicotinamide

Charge 0

This species takes part in one reaction (as a reactant in R NNAM). d M ncam c = −v (2587) dt 687

7.538 Species M nh4 c

Name Ammonium

Charge 1

1000 Produced by SBML2LATEX This species takes part in 41 reactions (as a reactant in R CTPS1, R GLNS, R GLNSP1, R GLNSP2, R GLNSP3, R PYDXO and as a product in R ADA, R ALAD L, R AMID4, R ARGDr, R ASNN, R ASPO1, R CYSTGL, R CYSTL, R CYTD, R DADA, R DALAOX, R DCTPD, R DCTPD2, R DCYTD, R DHPPDA, R- DHPPDA2, R GCC2, R GCCb, R GLUDx, R GLYCL, R GUAD, R HMBS, R NH4OHDs, R NH4t, R NNAM, R NTRIR2x, R PEAMNO, R PYAM5PO, R SADH, R SERD D, R SERD L, R SHSL4r, R THRD Lr, R- THZSN, R UREA). d M nh4 c = v + v + v + v + v + v + v + v + v + v + v dt 31 72 81 99 105 111 177 178 182 190 193 + v209 + v210 + v211 + v231 + v232 + v456 + v458 + v476 + v486 + v512 + 4v527 + v685 + v686 + v687 + v716 + v765 + v864 + 2v892 + v900 + v901 + v915 + v946 + v951 + 2v1015 − v169 − v469 − v470 − v471 − v472 − v866 (2588)

7.539 Species M nh4 e Name Ammonium

Charge 1

This species takes part in two reactions (as a reactant in R EX nh4 e, R NH4t). d M nh4 e = −v − v (2589) dt 312 686

7.540 Species M nh4oh c Name Ammonium hydroxide

Charge 0

This species takes part in three reactions (as a reactant in R NH4OHDs and as a product in R- NTRIRx, R NTRIRy). d M nh4oh c = v + v − v (2590) dt 717 718 685

7.541 Species M nicrnt c Name Nicotinate D-ribonucleotide

Charge -2

This species takes part in four reactions (as a reactant in R NNAT, R NNDMBRT and as a product in R NAPRTr, R NNDPR). d M nicrnt c = v + v − v − v (2591) dt 673 690 688 689

Produced by SBML2LATEX 1001 7.542 Species M no2 c

Name Nitrite

Charge -1

This species takes part in seven reactions (as a reactant in R NARK, R NO3t7, R NTRIR2x, R- NTRIRx, R NTRIRy and as a product in R NO3R1, R NO3R2).

d M no2 c = v + v − v − v − v − v − v (2592) dt 692 693 674 694 716 717 718

7.543 Species M no2 e

Name Nitrite

Charge -1

This species takes part in three reactions (as a reactant in R EX no2 e and as a product in R NARK, R NO3t7).

d M no2 e = v + v − v (2593) dt 674 694 313

7.544 Species M no3 c

Name Nitrate

Charge -1

This species takes part in four reactions (as a reactant in R NO3R1, R NO3R2 and as a product in R NO, R NO3t7).

d M no3 c = v + v − v − v (2594) dt 691 694 692 693

7.545 Species M no3 e

Name Nitrate

Charge -1

This species takes part in two reactions (as a reactant in R EX no3 e, R NO3t7).

d M no3 e = −v − v (2595) dt 314 694

1002 Produced by SBML2LATEX 7.546 Species M no c Name Nitric oxide

Charge 0

This species takes part in two reactions (as a reactant in R NO and as a product in R NOt). d M no c = v − v (2596) dt 695 691

7.547 Species M no e Name Nitric oxide

Charge 0

This species takes part in two reactions (as a reactant in R EX no e, R NOt). d M no e = −v − v (2597) dt 315 695

7.548 Species M o2 c Name O2

Charge 0

This species takes part in 29 reactions (as a reactant in R ASPO1, R CPPPGO, R CYO1b, R CYTBD, R CYTBD2, R DALAOX, R DESAT16, R DESAT18, R FAH4, R FAS161, R FAS181, R GLYCTO1, R LO, R MCBTS, R MCBTS2, R MCBTS3, R PDX5PO, R PEAMNO, R PHTHCLS, R PHTO, R PPPGO, R PYAM5PO, R PYDXNO, R PYDXO, R R05217, R UAMRH and as a product in R CAT, R O2t, R- SPODM). d M o2 c = v + v + v − v − v − 0.5v − 0.5v − 0.5v − v − v dt 129 720 919 111 166 173 180 181 193 213 − v214 − v355 − v370 − v372 − v487 − v573 − 2v593 − 2v594 − 3.5v595 − v764 − v765 − v792 − 2v797 − 1.5v826 − v864 − v865 − 0.5v866 − 0.5v872 − v992 (2598)

7.549 Species M o2 e Name O2

Charge 0

This species takes part in two reactions (as a reactant in R EX o2 e, R O2t). d M o2 e = −v − v (2599) dt 316 720

Produced by SBML2LATEX 1003 7.550 Species M o2s c Name Superoxide anion

Charge -1

This species takes part in three reactions (as a reactant in R NO, R SPODM and as a product in R PHTO). d M o2s c = 2v − v − 2v (2600) dt 797 691 919

7.551 Species M oaa c Name Oxaloacetate

Charge -2

This species takes part in ten reactions (as a reactant in R CS, R PEPCK re, R PPCKr and as a product in R ASPO1, R ASPTA, R CITL, R CITLr, R MDH, R PC, R TARTD). d M oaa c = v + v + v + v + v + v + v − v − v − v (2601) dt 111 113 146 147 599 748 930 168 766 813

7.552 Species M occoa c Name Octanoyl-CoA (n-C8:0CoA)

Charge -4

This species takes part in two reactions (as a reactant in R MCBTS3 and as a product in R- FACOAL80). d M occoa c = v − v (2602) dt 352 595

7.553 Species M ocdca c Name octadecanoate (n-C18:0)

Charge -1

This species takes part in 14 reactions (as a reactant in R 2AGPEAT180, R FACOAL180, R FAO3, R FAS200, R FAS240 L, R FASm2002, R PATS, R TRIATS, R biomass Mtb 9 60atp and as a product in R FACOAE180, R FAS180, R LPLIPAL2E180, R OCDCAt2, R PLIPA1E180).

d M ocdca c = v + v + v + v + v − v − v − v dt 345 371 575 722 803 2 349 365 (2603) − v373 − v374 − v382 − v747 − 2v972 − 0.034837v1025

1004 Produced by SBML2LATEX 7.554 Species M ocdca e

Name octadecanoate (n-C18:0)

Charge -1

This species takes part in two reactions (as a reactant in R EX ocdca e, R OCDCAt2).

d M ocdca e = −v − v (2604) dt 317 722

7.555 Species M ocdcea c

Name octadecenoate (n-C18:1)

Charge -1

This species takes part in four reactions (as a reactant in R FACOAL181, R FAO10, R biomass- Mtb 9 60atp and as a product in R FAS181).

d M ocdcea c = v − v − v − 0.009849v (2605) dt 372 350 362 1025

7.556 Species M octa c

Name octanoate (n-C8:0)

Charge -1

This species takes part in four reactions (as a reactant in R FACOAL80, R FAS100, R FASm180 and as a product in R FAS80 L).

d M octa c = v − v − v − v (2606) dt 376 352 366 379

7.557 Species M octdp c

Name all-trans-Octaprenyl diphosphate

Charge -3

This species takes part in three reactions (as a reactant in R DHNAOT, R DHNAOT2 and as a product in R OCTDPS).

d M octdp c = v − v − v (2607) dt 724 223 224

Produced by SBML2LATEX 1005 7.558 Species M odecoa c

Name Octadecenoyl-CoA (n-C18:1CoA)

Charge -4

This species takes part in four reactions (as a reactant in R MCBTS, R MCBTS2 and as a product in R DESAT18, R FACOAL181).

d M odecoa c = v + v − v − v (2608) dt 214 350 593 594

7.559 Species M ohpb c

Name 2-Oxo-3-hydroxy-4-phosphobutanoate

Charge -3

This species takes part in two reactions (as a reactant in R OHPBAT and as a product in R PERD).

d M ohpb c = v − v (2609) dt 767 725

7.560 Species M omdtria c

Name octa-methyl dotriacontanoic acid (C32:0 with 7 methyl branches)

Charge -1

This species takes part in one reaction (as a product in R FASm3001).

d M omdtria c = v (2610) dt 396

7.561 Species M omtta c

Name octa-methyl tetracontatricosanoic acid (C34:0, 8 methyl-branched carbons)

Charge -1

This species takes part in four reactions (as a reactant in R FAH4, R TATS, R TATSO and as a product in R FASm340).

d M omtta c = v − v − 2v − 2v (2611) dt 398 355 933 934

1006 Produced by SBML2LATEX 7.562 Species M orn c

Name Ornithine

Charge 1

This species takes part in ﬁve reactions (as a reactant in R OCBT, R ORNTA and as a product in R ACODA, R ORNTAC, R ORNt).

d M orn c = v + v + v − v − v (2612) dt 23 730 731 721 729

7.563 Species M orn e

Name Ornithine

Charge 1

This species takes part in two reactions (as a reactant in R EX orn e, R ORNt).

d M orn e = −v − v (2613) dt 318 731

7.564 Species M orot5p c

Name Orotidine 5’-phosphate

Charge -3

This species takes part in two reactions (as a reactant in R OMPDC, R ORPT).

d M orot5p c = −v − v (2614) dt 727 732

7.565 Species M orot c

Name Orotate

Charge -1

This species takes part in four reactions (as a product in R DHORD2, R DHORD3, R DHORD5, R- ORPT).

d M orot c = v + v + v + v (2615) dt 227 228 229 732

Produced by SBML2LATEX 1007 7.566 Species M oxa c

Name Oxalate

Charge -2

This species takes part in two reactions (as a reactant in R OXACOAL and as a product in R GLXO1).

d M oxa c = v − v (2616) dt 482 733

7.567 Species M oxalcoa c

Name Oxalyl-CoA

Charge -5

This species takes part in two reactions (as a reactant in R OXCDC and as a product in R OXACOAL).

d M oxalcoa c = v − v (2617) dt 733 734

7.568 Species M pa160190 c

Name 1,2-sn-glycerol 3-phosphate

Charge -2

This species takes part in four reactions (as a reactant in R DASYN160190, R biomass Mtb 9- 60atp and as a product in R AGPAT160190, R CDAPPA160190).

d M pa160190 c = v + v − v − 0.006798v (2618) dt 58 135 198 1025

7.569 Species M pa160 c

Name 1,2-dihexadecanoyl-sn-glycerol 3-phosphate

Charge -2

This species takes part in six reactions (as a reactant in R DASYN160, R PAPA160, R biomass- Mtb 9 60atp and as a product in R AGPAT160, R CDAPPA160, R DAGK160).

d M pa160 c = v + v + v − v − v − 0.00724v (2619) dt 57 134 192 197 742 1025

1008 Produced by SBML2LATEX 7.570 Species M pa190190 c

Name 1,2-sn-glycerol 3-phosphate

Charge -2

This species takes part in four reactions (as a reactant in R DASYN190190, R biomass Mtb 9- 60atp and as a product in R AGPAT190, R CDAPPA190).

d M pa190190 c = v + v − v − 0.006407v (2620) dt 59 136 199 1025

7.571 Species M pac c

Name Phenylacetic acid

Charge -1

This species takes part in two reactions (as a product in R ALDD19x, R PACt2r).

d M pac c = v + v (2621) dt 78 740

7.572 Species M pac e

Name Phenylacetic acid

Charge -1

This species takes part in two reactions (as a reactant in R EX pac e, R PACt2r).

d M pac e = −v − v (2622) dt 319 740

7.573 Species M pacald c

Name Phenylacetaldehyde

Charge 0

This species takes part in two reactions (as a reactant in R ALDD19x and as a product in R- PEAMNO).

d M pacald c = v − v (2623) dt 765 78

Produced by SBML2LATEX 1009 7.574 Species M palmACP c

Name Palmitoyl-ACP (n-C16:0ACP)

Charge -1

This species takes part in three reactions (as a reactant in R AGPAT160, R G3PAT160 and as a product in R AACPS3).

d M palmACP c = v − v − v (2624) dt 7 57 442

7.575 Species M pan4p c

Name Pantetheine 4’-phosphate

Charge -2

This species takes part in two reactions (as a reactant in R PTPATi and as a product in R PPCDC).

d M pan4p c = v − v (2625) dt 812 856

7.576 Species M pant DASH R c

Name (R)-Pantoate

Charge -1

This species takes part in two reactions (as a reactant in R PANTS and as a product in R DPR).

d M pant DASH R c = v − v (2626) dt 243 741

7.577 Species M pap c

Name Adenosine 3’,5’-bisphosphate

Charge -4

This species takes part in four reactions (as a reactant in R BPNT and as a product in R ACPS1, R PAPR, R TRESULT).

d M pap c = v + v + v − v (2627) dt 27 746 970 125

1010 Produced by SBML2LATEX 7.578 Species M paps c

Name 3’-Phosphoadenylyl sulfate

Charge -4

This species takes part in three reactions (as a reactant in R PAPR, R TRESULT and as a product in R ADSK).

d M paps c = v − v − v (2628) dt 49 746 970

7.579 Species M pat c

Name penta-acyl trehalose

Charge 0

This species takes part in two reactions (as a reactant in R biomass Mtb 9 60atp and as a product in R PATS).

d M pat c = v − 0.001251v (2629) dt 747 1025

7.580 Species M pdima c

Name phthiocerol dimycocerosate A (Mtb)

Charge 0

This species takes part in three reactions (as a reactant in R PDIMAT, R biomass Mtb 9 60atp and as a product in R PDIMAS).

d M pdima c = v − v − 2.73 · 10−4v (2630) dt 762 763 1025

7.581 Species M pdima e

Name phthiocerol dimycocerosate A (Mtb)

Charge 0

This species takes part in two reactions (as a reactant in R EX pdima e and as a product in R PDIMAT).

d M pdima e = v − v (2631) dt 763 320

Produced by SBML2LATEX 1011 7.582 Species M pdx5p c

Name Pyridoxine 5’-phosphate

Charge -2

This species takes part in one reaction (as a reactant in R PDX5PO).

d M pdx5p c = −v (2632) dt 764

7.583 Species M pe160 c

Name phosphatidylethanolamine (dihexadecanoyl, n-C16:0)

Charge 0

This species takes part in four reactions (as a reactant in R PLIPA1E160, R biomass Mtb 9- 60atp and as a product in R 2AGPEAT160, R PSD160).

d M pe160 c = v + v − v − 0.004061v (2633) dt 1 849 802 1025

7.584 Species M pe180 c

Name phosphatidylethanolamine (dioctadecanoyl, n-C18:0)

Charge 0

This species takes part in three reactions (as a reactant in R PLIPA1E180 and as a product in R 2AGPEAT180, R PSD180).

d M pe180 c = v + v − v (2634) dt 2 850 803

7.585 Species M peamn c

Name Phenethylamine

Charge 1

This species takes part in two reactions (as a reactant in R PEAMNO and as a product in R- PHYCBOXL).

d M peamn c = v − v (2635) dt 798 765

1012 Produced by SBML2LATEX 7.586 Species M pep c

Name Phosphoenolpyruvate

Charge -3

This species takes part in eight reactions (as a reactant in R DDPA, R PSCVT, R PYK, R UAGCVT and as a product in R ENO, R PEPCK re, R PPCKr, R PPDK).

d M pep c = v + v + v + v − v − v − v − v (2636) dt 254 766 813 818 212 848 867 985

7.587 Species M peptido EC c

Name Peptidoglycan subunit of Escherichia coli

Charge -2

This species takes part in one reaction (as a product in R PPTGS).

d M peptido EC c = v (2637) dt 827

7.588 Species M peptido TB1 c

Name peptidoglycan subunit (for Mycobacterium tuberculosis)

Charge -1

This species takes part in two reactions (as a reactant in R biomass Mtb 9 60atp and as a product in R PPTGS TB1).

d M peptido TB1 c = v − 0.01885v (2638) dt 828 1025

7.589 Species M peptido TB2 c

Name peptidoglycan subunit (for Mycobacterium tuberculosis)

Charge -1

This species takes part in two reactions (as a reactant in R biomass Mtb 9 60atp and as a product in R PPTGS TB2).

d M peptido TB2 c = v − 0.01885v (2639) dt 829 1025

Produced by SBML2LATEX 1013 7.590 Species M pg160190 c

Name Phosphatidylglycerol (hexadecanoyl, methylstearoyl)

Charge -1

This species takes part in three reactions (as a reactant in R CLPNS160190, R biomass Mtb 9- 60atp and as a product in R PGPP160190).

d M pg160190 c = v − 2v − 0.00613v (2640) dt 780 149 1025

7.591 Species M pg160 c

Name Phosphatidylglycerol (dihexadecanoyl, n-C16:0)

Charge -1

This species takes part in two reactions (as a reactant in R biomass Mtb 9 60atp and as a product in R PGPP160).

d M pg160 c = v − 0.006487v (2641) dt 779 1025

7.592 Species M pg190 c

Name Phosphatidylglycerol (dimethylstearoyl, C19:0)

Charge -1

This species takes part in two reactions (as a reactant in R biomass Mtb 9 60atp and as a product in R PGPP190).

d M pg190 c = v − 0.00581v (2642) dt 781 1025

7.593 Species M pgp160190 c

Name Phosphatidylglycerophosphate (hexadecanoyl, tuberculostearoyl, C16:0, C19:0)

Charge -3

This species takes part in two reactions (as a reactant in R PGPP160190 and as a product in R PGSA160190).

d M pgp160190 c = v − v (2643) dt 784 780

1014 Produced by SBML2LATEX 7.594 Species M pgp160 c

Name Phosphatidylglycerophosphate (dihexadecanoyl, n-C16:0)

Charge -3

This species takes part in two reactions (as a reactant in R PGPP160 and as a product in R- PGSA160).

d M pgp160 c = v − v (2644) dt 783 779

7.595 Species M pgp190 c

Name Phosphatidylglycerophosphate (dituberculostearoyl, C19:0)

Charge -3

This species takes part in two reactions (as a reactant in R PGPP190 and as a product in R- PGSA190).

d M pgp190 c = v − v (2645) dt 785 781

7.596 Species M phdcaACP c

Name phenol palmitic acid ACP

Charge -1

This species takes part in three reactions (as a reactant in R PREPTHS2 and as a product in R- FASPHDCA, R PHDCATA).

d M phdcaACP c = v + v − v (2646) dt 377 786 840

7.597 Species M phdca c

Name phenol palmitic acid

Charge -1

This species takes part in three reactions (as a reactant in R FACOALPHDCA, R biomass Mtb 9- 60atp and as a product in R PHDCAt).

d M phdca c = v − v − 0.006453v (2647) dt 787 353 1025

Produced by SBML2LATEX 1015 7.598 Species M phdca e

Name phenol palmitic acid

Charge -1

This species takes part in two reactions (as a reactant in R EX phdca e, R PHDCAt).

d M phdca e = −v − v (2648) dt 321 787

7.599 Species M phdcacoa c

Name phenol palmitic coenzyme A

Charge -4

This species takes part in two reactions (as a reactant in R PHDCATA and as a product in R- FACOALPHDCA).

d M phdcacoa c = v − v (2649) dt 353 786

7.600 Species M phe DASH L c

Name L-Phenylalanine

Charge 0

This species takes part in four reactions (as a reactant in R PHETA1, R PHYCBOXL, R biomass- Mtb 9 60atp and as a product in R PHEt2r).

d M phe DASH L c = v − v − v − 0.048102v (2650) dt 789 788 798 1025

7.601 Species M phe DASH L e

Name L-Phenylalanine

Charge 0

This species takes part in two reactions (as a reactant in R EX phe DASH L e, R PHEt2r).

d M phe DASH L e = −v − v (2651) dt 322 789

1016 Produced by SBML2LATEX 7.602 Species M pheme c Name Protoheme

Charge -2 This species takes part in two reactions (as a product in R FCLT, R FCLT2). d M pheme c = v + v (2652) dt 402 403

7.603 Species M phom c Name O-Phospho-L-homoserine

Charge -2 This species takes part in two reactions (as a reactant in R THRS and as a product in R HSK). d M phom c = v − v (2653) dt 538 947

7.604 Species M phpyr c Name Phenylpyruvate

Charge -1 This species takes part in two reactions (as a product in R PHETA1, R PPNDH). d M phpyr c = v + v (2654) dt 788 825

7.605 Species M phthcl c Name phthiocol (oxidized)

Charge 0 This species takes part in four reactions (as a product in R PHTHCLR1, R PHTHCLR2, R PHTHCLS, R PHTO). d M phthcl c = v + v + v + v (2655) dt 790 791 792 797

7.606 Species M phthclh2 c Name phthiocol (reduced)

Charge 0 This species takes part in three reactions (as a reactant in R PHTHCLR1, R PHTHCLR2, R PHTO). d M phthclh2 c = −v − v − v (2656) dt 790 791 797

Produced by SBML2LATEX 1017 7.607 Species M phthdl c Name phthiodolone

Charge 0

This species takes part in two reactions (as a reactant in R PHTHS and as a product in R PHTHDLS). d M phthdl c = v − v (2657) dt 793 795

7.608 Species M phthiocerol c Name phthiocerol A

Charge 0

This species takes part in two reactions (as a reactant in R PDIMAS and as a product in R PHTHS). d M phthiocerol c = v − v (2658) dt 795 762

7.609 Species M phthr c Name O-Phospho-4-hydroxy-L-threonine

Charge -2

This species takes part in two reactions (as a reactant in R 4HTHRS and as a product in R OHPBAT). d M phthr c = v − v (2659) dt 725 3

7.610 Species M pi c Name Phosphate

Charge -2

This species takes part in 147 reactions (as a reactant in R AGPR, R ASAD, R ATPS4r, R DURIPP, R GAPD, R GLCP, R PIt, R PPDK, R PPGKr, R PTAr, R PUNP1, R PUNP2, R PUNP3, R PUNP4, R PUNP5, R PUNP6, R PUNP7, R TMDPP and as a product in R 4HTHRS, R ACCOACr, R ACP1- FMN, R ADCPS1, R ADCPS2, R ADCYRS, R ADSS, R AHMMPS, R AICART2, R AIRC2, R ALAALAr, R ARB Dabc, R ARBabc, R ASPCT, R ATPS1, R BPNT, R CAATPS, R CBPS, R CHLabc, R CHORS, R CITabc, R COCHL, R CRNabc, R CTPS1, R CTPS2, R Cuabc, R Cut1, R DBTSr, R DCPDP, R- DCPDPP, R DCPDPP2, R DDPA, R DHFS, R DHQS, R DNMPPA, R FBP, R FE2abc, R FE3abc, R- FTHFCL, R FTHFL, R G5SD, R G5SD2, R GLCabc, R GLNS, R GLNSP1, R GLNSP2, R GLNSP3, R GLUCYS, R GLYBabc, R GLYC3Pabc, R GTHS, R GTPH1, R HISTP, R IACGAMS, R Kabc, R- LCTSabc, R MALTHPabc, R MALTabc, R MAN1PT2, R MCBTS, R MCBTS2, R MCBTS3, R METAT,

1018 Produced by SBML2LATEX R METabc, R MI1PP, R MI3PP, R MI4PP, R MN6PP, R MPML, R NTD1, R NTD10, R NTD11, R- NTD2, R NTD3, R NTD4, R NTD5, R NTD6, R NTD7, R NTD8, R NTD9, R OCBT, R OPAH, R PAPA160, R PC, R PGLYCP, R PGPP160, R PGPP160190, R PGPP190, R PIabc, R PMDPHT, R PPA, R PPCOAC, R PPNCL, R PRAGSr, R PRAIS, R PRASCS, R PRFGS, R PROabc, R PSCVT, R PSP L, R QULNS, R RBFSa, R RIBabc, R RZ5PP, R SADT2, R SUCOAS, R SULabc, R THFGLUS, R THMDP, R THRS, R TRE6PP, R TREabc, R TSULabc, R UAAGDS, R UAAGLS1, R UAAGLS2, R UAGCVT, R UAMAGS, R UAMAS, R UDCPDP, R UGAGDS, R UGLDDS1, R UGLDDS2, R UGMAGS, R UGMAS, R UGMDDS, R- UGMDDS2, R XYLabc, R biomass Mtb 9 60atp). d M pi c = v +v +v +v +v +4v +v +v +v +v +v +v +v +v +v dt 3 14 26 33 34 36 52 63 65 66 71 95 96 109 117 + v125 + v128 + v133 + v140 + v143 + v148 + v156 + v167 + v169 + v170 + v188 + v189 + v201 + v202 + v203 + v204 + v212 + v222 + v235 + v239 + v400 + v406 + v408 + v425 + v427 + v446 + v447 + v467 + v469 + v470 + v471 + v472 + v474 + v483 + v484 + v504 + 2v510 + v525 + v542 + v566 + v569 + v584 + v585 + v588 + v593 + v594 + v595 + v605 + v611 + v614 + v616 + v617 + v624 + v630 + v697 + v698 + v699 + v700 + v701 + v702 + v703 + v704 + v705 + v706 + v707 + v721 + v728 + v742 + v748 + v776 + v779 + v780 + v781 + 2v799 + v805 + 2v809 + v814 + v821 + v830 + v831 + v834 + v842 + v845 + v848 + v852 + v871 + v876 + v881 + v891 + v894 + v926 + v928 + v944 + 2v945 + v947 + v968 + v971 + v978 + v982 + v983 + v984 + v985 + v990 + v991 + v994 + v1001 + v1003 + v1004 + v1005 + v1006 + v1007 + v1008 + v1023 + 60v1025 − v60 − v104 − v118 − v248 − v454 −v465 −v800 −v818 −v819 −v855 −v857 −v858 −v859 −v860 −v861 −v862 −v863 −v955 (2660)

7.611 Species M pi e

Name Phosphate

Charge -2

This species takes part in three reactions (as a reactant in R EX pi e, R PIabc and as a product in R PIt). d M pi e = v − v − v (2661) dt 800 323 799

7.612 Species M pmcoa c

Name Pimeloyl-CoA

Charge -5

This species takes part in one reaction (as a reactant in R AOXSr). d M pmcoa c = −v (2662) dt 88

Produced by SBML2LATEX 1019 7.613 Species M pmhexc c

Name penta-methyl hexacosanoate

Charge -1

This species takes part in two reactions (as a reactant in R FASm2601 and as a product in R- FASm2401).

d M pmhexc c = v − v (2663) dt 387 390

7.614 Species M pmocta c

Name penta-methyl octacosanoate

Charge -1

This species takes part in two reactions (as a reactant in R FASm300 and as a product in R- FASm2802).

d M pmocta c = v − v (2664) dt 394 395

7.615 Species M pmtcoa c

Name Palmitoyl-CoA (n-C16:0CoA)

Charge -4

This species takes part in six reactions (as a reactant in R DESAT16, R FACOAE160, R MANAT1, R MANAT2, R MANAT3 and as a product in R FACOAL160).

d M pmtcoa c = v − v − v − v − v − v (2665) dt 347 213 344 590 591 592

7.616 Species M pnto DASH R c

Name (R)-Pantothenate

Charge -1

This species takes part in two reactions (as a reactant in R PNTK and as a product in R PANTS).

d M pnto DASH R c = v − v (2666) dt 741 808

1020 Produced by SBML2LATEX 7.617 Species M ppa c

Name Propionate (n-C3:0)

Charge -1

This species takes part in three reactions (as a reactant in R ACS2 and as a product in R PPAtr, R PPCSCT).

d M ppa c = v + v − v (2667) dt 810 815 29

7.618 Species M ppa e

Name Propionate (n-C3:0)

Charge -1

This species takes part in two reactions (as a reactant in R EX ppa e, R PPAtr).

d M ppa e = −v − v (2668) dt 324 810

7.619 Species M ppal c

Name Propanal

Charge 0

This species takes part in one reaction (as a reactant in R MMSAD2).

d M ppal c = −v (2669) dt 622

7.620 Species M ppbng c

Name Porphobilinogen

Charge -1

This species takes part in two reactions (as a reactant in R HMBS and as a product in R PPBNGS).

d M ppbng c = v − 4v (2670) dt 811 527

Produced by SBML2LATEX 1021 7.621 Species M ppcoa c

Name Propanoyl-CoA

Charge -4

This species takes part in six reactions (as a reactant in R PPCOAC, R PPCSCT and as a product in R ACS2, R MMCD, R MMSAD1, R MMSAD2).

d M ppcoa c = v + v + v + v − v − v (2671) dt 29 618 621 622 814 815

7.622 Species M ppdima c

Name phenol phthiocerol dimycocerosate (Mtb)

Charge 0

This species takes part in four reactions (as a reactant in R PPDIMAT, R RPPDIMAS, R biomass- Mtb 9 60atp and as a product in R PPDIMAS).

d M ppdima c = v − v − v − 2.63 · 10−4v (2672) dt 816 817 889 1025

7.623 Species M ppdima e

Name phenol phthiocerol dimycocerosate (Mtb)

Charge 0

This species takes part in two reactions (as a reactant in R EX ppdima e and as a product in R PPDIMAT).

d M ppdima e = v − v (2673) dt 817 325

7.624 Species M pphn c

Name Prephenate

Charge -2

This species takes part in three reactions (as a reactant in R PPND, R PPNDH and as a product in R CHORM).

d M pphn c = v − v − v (2674) dt 142 824 825

1022 Produced by SBML2LATEX 7.625 Species M pphthdl c

Name phenolic phthiodiolone

Charge 0

This species takes part in two reactions (as a reactant in R PHTHS2 and as a product in R- PHTHDLS2).

d M pphthdl c = v − v (2675) dt 794 796

7.626 Species M pphthiocerol c

Name phenolphtiocerol

Charge 0

This species takes part in two reactions (as a reactant in R PPDIMAS and as a product in R- PHTHS2).

d M pphthiocerol c = v − v (2676) dt 796 816

7.627 Species M ppi c

Name Diphosphate

Charge -3

This species takes part in 96 reactions (as a reactant in R ORPT, R PPA, R PPK2 and as a product in R 2AGPEAT160, R 2AGPEAT180, R AACPS10, R AACPS11, R AACPS3, R ACBIPGT, R ACS, R ACS2, R ADK2, R ADNCYC, R ADPT, R ALATRS, R ANPRT, R ARGSS, R ASNS1, R ATPPRT, R- BACCL, R CIGAMS, R DASYN160, R DASYN160190, R DASYN190190, R DCPDPS, R DCPT, R- DCPT2, R DHNAOT, R DHNAOT2, R DHPS2, R DMATT, R DNTPPA, R DPPS, R DUTPDP, R FACOAL140, R FACOAL160, R FACOAL161, R FACOAL180, R FACOAL181, R FACOAL200, R FACOAL80, R- FACOALPHDCA, R FACOALPREPH, R FAO1, R FAO10, R FAO11, R FAO2, R FAO3, R FMNAT, R- FOLD3, R FORMCOAL, R G1PTT, R GALT, R GALUi, R GLGC, R GLUPRT, R GMPS2, R GRTT, R- GTPCII, R GTPCII2, R GUACYC, R GUAPRT, R HXPRT, R MAN1PT, R MEPCT, R METAT, R NADS2, R NAPRTr, R NNAT, R NNDPR, R NTPP2, R NTPP3, R NTPP4, R NTPP5, R NTPP7, R NTPP8, R- OCTDPS, R OXACOAL, R PANTS, R PPDK, R PPNCL2, R PPNCL3, R PRATPP, R PTPATi, R R05224, R SADT, R SADT2, R SUCBZL, R THZPSN, R TMPPP, R UAGDP, R UDCPDPS, R UDPDPS, R UDPDPS2, R UPPRT, R XPPT).

Produced by SBML2LATEX 1023 d M ppi c = v + v + v + v + v + v + v + v + v + v + v + v + v + v dt 1 2 5 6 7 12 28 29 38 42 48 75 86 101 + v106 + v116 + v119 + v145 + v197 + v198 + v199 + 7v205 + v207 + v208 + v223 + v224 + v233 + v236 + v240 + 7v242 + v249 + v346 + v347 + v348 + v349 + v350 + v351 + v352 + v353 + v354 + v361 + v362 + v363 + v364 + v365 + v412 + v413 + v416 + v440 + v451 + v452 + v468 + v477 + v495 + v500 + v507 + v508 + v511 + v513 + v541 + v587 + v604 + v605 + v670 + v673 + v688 + v690 + v708 + v709 + v710 + v711 + v712 + v713 + 5v724 + v733 + v741 + v818 + v822 + v823 + v835 + v856 + v874 + v893 + v894 + v922 + v950 + v965 + v986 + 8v995 + v996 + v997 + v1014 + v1021 − v732 − v809 − v820 (2677)

7.628 Species M ppp9 c

Name Protoporphyrin

Charge -2

This species takes part in four reactions (as a reactant in R FCLT, R FCLT2, R MPML and as a product in R PPPGO).

d M ppp9 c = v − v − v − v (2678) dt 826 402 403 630

7.629 Species M pppg9 c

Name Protoporphyrinogen IX

Charge -2

This species takes part in two reactions (as a reactant in R PPPGO and as a product in R CPPPGO).

d M pppg9 c = v − v (2679) dt 166 826

7.630 Species M pppi c

Name Inorganic triphosphate

Charge -4

This species takes part in seven reactions (as a reactant in R ADK2 and as a product in R CBIAT, R CBLAT, R CYRDAAT, R NTPTP1, R NTPTP2, R PPK2).

d M pppi c = v + v + v + v + v + v − v (2680) dt 131 132 174 714 715 820 38

1024 Produced by SBML2LATEX 7.631 Species M pram c Name 5-Phospho-beta-D-ribosylamine

Charge -1 This species takes part in two reactions (as a reactant in R PRAGSr and as a product in R GLUPRT). d M pram c = v − v (2681) dt 477 830

7.632 Species M pran c Name N-(5-Phospho-D-ribosyl)anthranilate

Charge -3 This species takes part in two reactions (as a reactant in R PRAIi and as a product in R ANPRT). d M pran c = v − v (2682) dt 86 832

7.633 Species M prbamp c Name 1-(5-Phosphoribosyl)-AMP

Charge -4 This species takes part in two reactions (as a reactant in R PRAMPC and as a product in R PRATPP). d M prbamp c = v − v (2683) dt 835 833

7.634 Species M prbatp c Name 1-(5-Phosphoribosyl)-ATP

Charge -6 This species takes part in two reactions (as a reactant in R PRATPP and as a product in R ATPPRT). d M prbatp c = v − v (2684) dt 116 835

7.635 Species M pre2 c Name dihydrosirohydrochlorin

Charge -8 This species takes part in one reaction (as a reactant in R SHCHD3). d M pre2 c = −v (2685) dt 908

Produced by SBML2LATEX 1025 7.636 Species M pre3a c Name Precorrin 3 A

Charge -7 This species takes part in two reactions (as a reactant in R R05217 and as a product in R PC20M). d M pre3a c = v − v (2686) dt 751 872

7.637 Species M pre3b c Name Precorrin 3B

Charge -6 This species takes part in two reactions (as a reactant in R PC17M and as a product in R R05217). d M pre3b c = v − v (2687) dt 872 750

7.638 Species M pre4 c Name Precorrin 4

Charge -8 This species takes part in two reactions (as a reactant in R PC11M and as a product in R PC17M). d M pre4 c = v − v (2688) dt 750 749

7.639 Species M pre5 c Name Precorrin 5

Charge -8 This species takes part in two reactions (as a reactant in R R05219 and as a product in R PC11M). d M pre5 c = v − v (2689) dt 749 873

7.640 Species M pre6a c Name Precorrin 6A

Charge -7 This species takes part in two reactions (as a reactant in R PC6AR and as a product in R R05219). d M pre6a c = v − v (2690) dt 873 752

1026 Produced by SBML2LATEX 7.641 Species M pre6b c

Name Precorrin 6B

Charge -7

This species takes part in two reactions (as a reactant in R PC6YM and as a product in R PC6AR).

d M pre6b c = v − v (2691) dt 752 753

7.642 Species M pre8 c

Name Precorrin 8

Charge -7

This species takes part in two reactions (as a reactant in R PC8XM and as a product in R PC6YM).

d M pre8 c = v − v (2692) dt 753 754

7.643 Species M prephthACP c

Name phthiocerol precursor bound ACP

Charge -1

This species takes part in three reactions (as a reactant in R PREPHACPH and as a product in R PREPTHS, R PREPTTA).

d M prephthACP c = v + v − v (2693) dt 839 841 837

7.644 Species M prephth c

Name phthiocerol precursor

Charge -1

This species takes part in three reactions (as a reactant in R FACOALPREPH, R PHTHDLS and as a product in R PREPHACPH).

d M prephth c = v − v − v (2694) dt 837 354 793

Produced by SBML2LATEX 1027 7.645 Species M prephthcoa c

Name phthiocerol precursor bound coenzyme A

Charge -4

This species takes part in two reactions (as a reactant in R PREPTTA and as a product in R- FACOALPREPH).

d M prephthcoa c = v − v (2695) dt 354 841

7.646 Species M prepphthACP c

Name phenolic phthiocerol precursor bound ACP

Charge -1

This species takes part in two reactions (as a reactant in R PREPPACPH and as a product in R- PREPTHS2).

d M prepphthACP c = v − v (2696) dt 840 838

7.647 Species M prepphth c

Name phenolic phthiocerol precursor

Charge -1

This species takes part in two reactions (as a reactant in R PHTHDLS2 and as a product in R- PREPPACPH).

d M prepphth c = v − v (2697) dt 838 794

7.648 Species M prfp c

Name 1-(5-Phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

Charge -4

This species takes part in two reactions (as a reactant in R PRMICIi and as a product in R- PRAMPC).

d M prfp c = v − v (2698) dt 833 843

1028 Produced by SBML2LATEX 7.649 Species M prlp c Name 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]-1-(5-phosphoribosyl)imidazole- 4-carboxamide

Charge -4

This species takes part in two reactions (as a reactant in R IG3PS and as a product in R PRMICIi). d M prlp c = v − v (2699) dt 843 547

7.650 Species M pro DASH L c Name L-Proline

Charge 0

This species takes part in six reactions (as a reactant in R PROD2, R biomass Mtb 9 60atp and as a product in R P5CR, R P5CRx, R PROabc, R PROt2r). d M pro DASH L c = v + v + v + v − v − 0.138034v (2700) dt 738 739 845 846 844 1025

7.651 Species M pro DASH L e Name L-Proline

Charge 0

This species takes part in three reactions (as a reactant in R EX pro DASH L e, R PROabc, R- PROt2r). d M pro DASH L e = −v − v − v (2701) dt 326 845 846

7.652 Species M prpp c Name 5-Phospho-alpha-D-ribose 1-diphosphate

Charge -5

This species takes part in 14 reactions (as a reactant in R ADPT, R ANPRT, R ATPPRT, R DCPT, R GLUPRT, R GUAPRT, R HXPRT, R NAPRTr, R NNDPR, R UPPRT, R XPPT and as a product in R- ARI, R ORPT, R PRPPS).

d M prpp c = v + v + v − v − v − v − v dt 103 732 847 48 86 116 207 (2702) − v477 − v513 − v541 − v673 − v690 − v1014 − v1021

Produced by SBML2LATEX 1029 7.653 Species M ps160 c

Name phosphatidylserine (dihexadecanoyl, n-C16:0)

Charge -1

This species takes part in two reactions (as a reactant in R PSD160 and as a product in R- PSSA160).

d M ps160 c = v − v (2703) dt 853 849

7.654 Species M ps180 c

Name phosphatidylserine (dioctadecanoyl, n-C18:0)

Charge -1

This species takes part in two reactions (as a reactant in R PSD180 and as a product in R- PSSA180).

d M ps180 c = v − v (2704) dt 854 850

7.655 Species M psd5p c

Name Pseudouridine 5’-phosphate

Charge -2

This species takes part in one reaction (as a product in R YUMPS).

d M psd5p c = v (2705) dt 1024

7.656 Species M pser DASH L c

Name O-Phospho-L-serine

Charge -2

This species takes part in two reactions (as a reactant in R PSP L and as a product in R PSERT).

d M pser DASH L c = v − v (2706) dt 851 852

1030 Produced by SBML2LATEX 7.657 Species M ptcys c Name N-Pantothenoylcysteine

Charge -1 This species takes part in one reaction (as a reactant in R PNCDC). d M ptcys c = −v (2707) dt 807

7.658 Species M ptd1ino160190 c Name phosphatidyl 1D myo inositol (C16:0, C19:0)

Charge -1 This species takes part in two reactions (as a reactant in R G16MTM1 and as a product in R- CDPPT160190). d M ptd1ino160190 c = v − v (2708) dt 139 430

7.659 Species M ptd1ino160 c Name phosphatidyl 1D myo inositol

Charge -1 This species takes part in two reactions (as a reactant in R PLCD and as a product in R CDPPT160). d M ptd1ino160 c = v − v (2709) dt 138 801

7.660 Species M ptrc c Name Putrescine

Charge 2 This species takes part in two reactions (as a reactant in R SPMS and as a product in R AGMT). d M ptrc c = v − v (2710) dt 56 918

7.661 Species M ptth c Name Pantetheine

Charge 0 This species takes part in one reaction (as a product in R PNCDC). d M ptth c = v (2711) dt 807

Produced by SBML2LATEX 1031 7.662 Species M pyam5p c Name Pyridoxamine 5’-phosphate

Charge -1 This species takes part in one reaction (as a reactant in R PYAM5PO). d M pyam5p c = −v (2712) dt 864

7.663 Species M pydam c Name Pyridoxamine

Charge 1 This species takes part in one reaction (as a product in R PYDXO). d M pydam c = v (2713) dt 866

7.664 Species M pydx5p c Name Pyridoxal 5’-phosphate

Charge -2 This species takes part in two reactions (as a product in R PDX5PO, R PYAM5PO). d M pydx5p c = v + v (2714) dt 764 864

7.665 Species M pydx c Name Pyridoxal

Charge 0 This species takes part in two reactions (as a reactant in R PYDXO and as a product in R PYDXNO). d M pydx c = v − v (2715) dt 865 866

7.666 Species M pydxn c Name Pyridoxine

Charge 0 This species takes part in one reaction (as a reactant in R PYDXNO). d M pydxn c = −v (2716) dt 865

1032 Produced by SBML2LATEX 7.667 Species M pyr c Name Pyruvate

Charge -1 This species takes part in 32 reactions (as a reactant in R ACHBS, R ACLS, R APATr, R DHDPS, R DXPS, R PC, R PDH, R PDHa, R PFL, R PPDK, R PYRDC and as a product in R ADCL, R ALAD L, R ALATA L, R ANS, R CHRPL, R CYSTL, R DALAOX, R HOPNTAL, R LDH L, R L LACD, R L LACD2, R L LACD3, R ME1, R PYK, R PYRt2r, R SALCS, R SERD D, R SERD L, R SHCHCS, R SHCHCS2, R THZSN). d M pyr c = v + v + v + v + v + v + v + v + v + v + v dt 32 72 74 87 144 178 193 532 570 577 578 + v579 + v600 + v867 + v869 + v895 + v900 + v901 + v905 + v906 + v951 − v20 − 2v22 − v89 − v220 − v251 − v748 − v757 − v758 − v769 − v818 − v868 (2717)

7.668 Species M pyr e Name Pyruvate

Charge -1 This species takes part in two reactions (as a reactant in R EX pyr e, R PYRt2r). d M pyr e = −v − v (2718) dt 327 869

7.669 Species M q8 c Name Ubiquinone-8

Charge 0 This species takes part in six reactions (as a reactant in R DHORD2, R GLYCTO2, R L LACD2, R NADH5 and as a product in R CYTBD, R NO3R1). d M q8 c = v + v − v − v − v − v (2719) dt 180 692 227 488 578 667

7.670 Species M q8h2 c Name Ubiquinol-8

Charge 0 This species takes part in six reactions (as a reactant in R CYTBD, R NO3R1 and as a product in R DHORD2, R GLYCTO2, R L LACD2, R NADH5). d M q8h2 c = v + v + v + v − v − v (2720) dt 227 488 578 667 180 692

Produced by SBML2LATEX 1033 7.671 Species M q c

Name Ubiquinone

Charge 0

This species takes part in three reactions (as a reactant in R NADH2r, R QRr and as a product in R CYO1a).

d M q c = v − v − v (2721) dt 172 666 870

7.672 Species M qh2 c

Name Ubiquinol

Charge 0

This species takes part in three reactions (as a reactant in R CYO1a and as a product in R NADH2r, R QRr).

d M qh2 c = v + v − v (2722) dt 666 870 172

7.673 Species M quln c

Name Quinolinate

Charge -2

This species takes part in two reactions (as a reactant in R NNDPR and as a product in R QULNS).

d M quln c = v − v (2723) dt 871 690

7.674 Species M r1p c

Name alpha-D-Ribose 1-phosphate

Charge -2

This species takes part in four reactions (as a product in R PUNP1, R PUNP3, R PUNP5, R PUNP7).

d M r1p c = v + v + v + v (2724) dt 857 859 861 863

1034 Produced by SBML2LATEX 7.675 Species M r5p c Name alpha-D-Ribose 5-phosphate

Charge -2 This species takes part in ﬁve reactions (as a reactant in R PRPPS, R RPI, R TKT1, R YUMPS and as a product in R RBK). d M r5p c = v − v − v − v − v (2725) dt 878 847 888 952 1024

7.676 Species M ragund c Name rhamanosyl-N-acetylglucosamyl-undecaprenyl diphosphate

Charge -2 This species takes part in two reactions (as a reactant in R GALFT and as a product in R O16RHAT). d M ragund c = v − v (2726) dt 719 449

7.677 Species M rbl DASH D c Name D-Ribulose

Charge 0 This species takes part in two reactions (as a reactant in R RBK Dr and as a product in R ARABI). d M rbl DASH D c = v − v (2727) dt 92 879

7.678 Species M rbl DASH L c Name L-Ribulose

Charge 0 This species takes part in two reactions (as a reactant in R RBK L1r and as a product in R ARAI). d M rbl DASH L c = v − v (2728) dt 94 880

7.679 Species M rdmbzi c Name N1-(alpha-D-ribosyl)-5,6-dimethylbenzimidazole

Charge 0 This species takes part in two reactions (as a reactant in R ADOCBLS and as a product in R RZ5PP). d M rdmbzi c = v − v (2729) dt 891 47

Produced by SBML2LATEX 1035 7.680 Species M rhcys c

Name S-Ribosyl-L-homocysteine

Charge 0

This species takes part in one reaction (as a product in R AHCYSNS).

d M rhcys c = v (2730) dt 62

7.681 Species M rib DASH D c

Name D-Ribose

Charge 0

This species takes part in four reactions (as a reactant in R RBK, R biomass Mtb 9 60atp and as a product in R INSH, R RIBabc).

d M rib DASH D c = v + v − v − 0.021723v (2731) dt 556 881 878 1025

7.682 Species M rib DASH D e

Name D-Ribose

Charge 0

This species takes part in two reactions (as a reactant in R EX rib DASH D e, R RIBabc).

d M rib DASH D e = −v − v (2732) dt 328 881

7.683 Species M ribflv c

Name Riboﬂavin

Charge 0

This species takes part in three reactions (as a reactant in R RBFK and as a product in R ACP1- FMN, R RBFSb).

d M ribﬂv c = v + v − v (2733) dt 26 877 875

1036 Produced by SBML2LATEX 7.684 Species M rmyc c

Name mycolate compounds (all)

Charge -1

This species takes part in ﬁve reactions (as a product in R MYCFLUX1, R MYCFLUX2, R MYCFLUX3, R MYCFLUX4, R MYCFLUX5).

d M rmyc c = v + v + v + v + v (2734) dt 650 651 652 653 654

7.685 Species M rppdima c

Name rhamnose phenol phthiocerol dimycocerosate (Mtb)

Charge 0

This species takes part in two reactions (as a reactant in R RRPPDIMAS and as a product in R- RPPDIMAS).

d M rppdima c = v − v (2735) dt 889 890

7.686 Species M rrppdima c

Name rhamnose rhamnose phenol phthiocerol dimycocerosate (Mtb)

Charge 0

This species takes part in two reactions (as a reactant in R FRRPPDIMAS and as a product in R RRPPDIMAS).

d M rrppdima c = v − v (2736) dt 890 424

7.687 Species M ru5p DASH D c

Name D-Ribulose 5-phosphate

Charge -2

This species takes part in ﬁve reactions (as a reactant in R DB4PS, R RPE and as a product in R GND, R RBK Dr, R RPI).

d M ru5p DASH D c = v + v + v − v − v (2737) dt 498 879 888 200 887

Produced by SBML2LATEX 1037 7.688 Species M ru5p DASH L c Name L-Ribulose 5-phosphate

Charge -2 This species takes part in one reaction (as a product in R RBK L1r). d M ru5p DASH L c = v (2738) dt 880

7.689 Species M s7p c Name Sedoheptulose 7-phosphate

Charge -2 This species takes part in two reactions (as a reactant in R TALA and as a product in R TKT1). d M s7p c = v − v (2739) dt 952 929

7.690 Species M s c Name Sulfur

Charge 0 This species takes part in one reaction (as a reactant in R BTS3r). d M s c = −2v (2740) dt 127

7.691 Species M salc c Name Salicylate

Charge -1 This species takes part in four reactions (as a reactant in R MCBTS, R MCBTS2, R MCBTS3 and as a product in R SALCS). d M salc c = v − v − v − v (2741) dt 895 593 594 595

7.692 Species M sbzcoa c Name O-Succinylbenzoyl-CoA

Charge -5 This species takes part in two reactions (as a reactant in R NPHS and as a product in R SUCBZL). d M sbzcoa c = v − v (2742) dt 922 696

1038 Produced by SBML2LATEX 7.693 Species M scl2 c Name sirohydrochlorin 2

Charge -8 This species takes part in two reactions (as a reactant in R SHCHF2 and as a product in R SHCHD3). d M scl2 c = v − v (2743) dt 908 910

7.694 Species M scl c Name sirohydrochlorin

Charge -7 This species takes part in three reactions (as a reactant in R SHCHF, R SHCHF3 and as a product in R SHCHD2). d M scl c = v − v − v (2744) dt 907 909 911

7.695 Species M sdhlam c Name S-Succinyldihydrolipoamide

Charge -1 This species takes part in one reaction (as a reactant in R AKGDb). d M sdhlam c = −v (2745) dt 69

7.696 Species M selcys c Name Selenocysteine

Charge 0 This species takes part in one reaction (as a reactant in R SELCYSLY). d M selcys c = −v (2746) dt 898

7.697 Species M seln c Name Selenide

Charge -1 This species takes part in one reaction (as a product in R SELCYSLY). d M seln c = v (2747) dt 898

Produced by SBML2LATEX 1039 7.698 Species M ser DASH D c

Name D-Serine

Charge 0

This species takes part in two reactions (as a reactant in R SERD D and as a product in R- DSERt2r). d M ser DASH D c = v − v (2748) dt 245 900

7.699 Species M ser DASH D e

Name D-Serine

Charge 0

This species takes part in two reactions (as a reactant in R DSERt2r, R EX ser DASH D e).

d M ser DASH D e = −v − v (2749) dt 245 329

7.700 Species M ser DASH L c

Name L-Serine

Charge 0

This species takes part in 13 reactions (as a reactant in R CYSTS, R GHMT2, R MCBTS2, R MCBTS3, R PSSA160, R PSSA180, R SERAT, R SERD L, R TRPS1, R TRPS2, R biomass Mtb 9 60atp and as a product in R PSP L, R SERt2r).

d M ser DASH L c = v + v − v − v − v − v − v dt 852 902 179 463 594 595 853 (2750) − v854 − v899 − v901 − v973 − v974 − 0.143397v1025

7.701 Species M ser DASH L e

Name L-Serine

Charge 0

This species takes part in two reactions (as a reactant in R EX ser DASH L e, R SERt2r).

d M ser DASH L e = −v − v (2751) dt 330 902

1040 Produced by SBML2LATEX 7.702 Species M seramp c Name L-seryl-AMP

Charge 0 This species takes part in one reaction (as a reactant in R ENTCS). d M seramp c = −3v (2752) dt 255

7.703 Species M sheme c Name Siroheme

Charge -8 This species takes part in three reactions (as a product in R SHCHF, R SHCHF2, R SHCHF3). d M sheme c = v + v + v (2753) dt 909 910 911

7.704 Species M skm5p c Name Shikimate 5-phosphate

Charge -3 This species takes part in two reactions (as a reactant in R PSCVT and as a product in R SHKK). d M skm5p c = v − v (2754) dt 913 848

7.705 Species M skm c Name Shikimate

Charge -1 This species takes part in three reactions (as a reactant in R SHKK and as a product in R SHK3Dr, R SKMt2). d M skm c = v + v − v (2755) dt 912 916 913

7.706 Species M skm e Name Shikimate

Charge -1 This species takes part in two reactions (as a reactant in R EX skm e, R SKMt2). d M skm e = −v − v (2756) dt 331 916

Produced by SBML2LATEX 1041 7.707 Species M sl1 c

Name sulfonated tetra-acyl trehalose

Charge -1

This species takes part in two reactions (as a reactant in R biomass Mtb 9 60atp and as a product in R TATSO).

d M sl1 c = v − 0.001137v (2757) dt 934 1025

7.708 Species M sl26da c

Name N-Succinyl-LL-2,6-diaminoheptanedioate

Charge -2

This species takes part in two reactions (as a reactant in R SDPDS, R SDPTA).

d M sl26da c = −v − v (2758) dt 896 897

7.709 Species M sl2a6o c

Name N-Succinyl-2-L-amino-6-oxoheptanedioate

Charge -3

This species takes part in two reactions (as a product in R SDPTA, R THDPS).

d M sl2a6o c = v + v (2759) dt 897 943

7.710 Species M so3 c

Name Sulﬁte

Charge -2

This species takes part in four reactions (as a product in R CYANST, R PAPR, R SULR, R THSFST).

d M so3 c = v + v + v + v (2760) dt 171 746 927 949

1042 Produced by SBML2LATEX 7.711 Species M so4 c

Name Sulfate

Charge -2

This species takes part in three reactions (as a reactant in R SADT, R SADT2 and as a product in R SULabc).

d M so4 c = v − v − v (2761) dt 928 893 894

7.712 Species M so4 e

Name Sulfate

Charge -2

This species takes part in two reactions (as a reactant in R EX so4 e, R SULabc).

d M so4 e = −v − v (2762) dt 332 928

7.713 Species M spmd c

Name Spermidine

Charge 3

This species takes part in one reaction (as a product in R SPMS).

d M spmd c = v (2763) dt 918

7.714 Species M ssaltpp c

Name Succinate semialdehyde-thiamin diphosphate anion

Charge -3

This species takes part in two reactions (as a reactant in R SHCHCS2 and as a product in R- OXGDC2).

d M ssaltpp c = v − v (2764) dt 736 906

Produced by SBML2LATEX 1043 7.715 Species M stcoa c

Name Stearoyl-CoA (n-C18:0CoA)

Charge -4

This species takes part in three reactions (as a reactant in R DESAT18, R FACOAE180 and as a product in R FACOAL180).

d M stcoa c = v − v − v (2765) dt 349 214 345

7.716 Species M sucarg c

Name N2-Succinyl-L-arginine

Charge -1

This species takes part in two reactions (as a reactant in R SADH and as a product in R AST).

d M sucarg c = v − v (2766) dt 115 892

7.717 Species M sucbz c

Name o-Succinylbenzoate

Charge -2

This species takes part in two reactions (as a reactant in R SUCBZL and as a product in R SUCBZS).

d M sucbz c = v − v (2767) dt 923 922

7.718 Species M succ c

Name Succinate

Charge -2

This species takes part in 18 reactions (as a reactant in R PPCSCT, R SUCD1i, R SUCOAS, R- TARTRt7 and as a product in R ASPO5, R FRD, R FRD2, R FRD3, R FRD5, R ICL, R OCOAT1r, R SDPDS, R SGDS, R SHSL1r, R SHSL4r, R SSALx, R SSALy, R SUCCt2r).

d M succ c = v + v + v + v + v + v + v + v + v dt 112 417 418 419 420 545 723 896 903 (2768) + v914 + v915 + v920 + v921 + v924 − v815 − v925 − v926 − v931

1044 Produced by SBML2LATEX 7.719 Species M succ e

Name Succinate

Charge -2

This species takes part in three reactions (as a reactant in R EX succ e, R SUCCt2r and as a product in R TARTRt7).

d M succ e = v − v − v (2769) dt 931 333 924

7.720 Species M succoa c

Name Succinyl-CoA

Charge -5

This species takes part in eight reactions (as a reactant in R AST, R HSST, R MMM2r, R OCOAT1r, R THDPS and as a product in R AKGDb, R PPCSCT, R SUCOAS).

d M succoa c = v + v + v − v − v − v − v − v (2770) dt 69 815 926 115 539 620 723 943

7.721 Species M sucglu c

Name N2-Succinyl-L-glutamate

Charge -3

This species takes part in two reactions (as a reactant in R SGDS and as a product in R SGSAD).

d M sucglu c = v − v (2771) dt 904 903

7.722 Species M sucgsa c

Name N2-Succinyl-L-glutamate 5-semialdehyde

Charge -2

This species takes part in two reactions (as a reactant in R SGSAD and as a product in R SOTA).

d M sucgsa c = v − v (2772) dt 917 904

Produced by SBML2LATEX 1045 7.723 Species M suchms c

Name O-Succinyl-L-homoserine

Charge -1

This species takes part in three reactions (as a reactant in R SHSL1r, R SHSL4r and as a product in R HSST).

d M suchms c = v − v − v (2773) dt 539 914 915

7.724 Species M sucorn c

Name N2-Succinyl-L-ornithine

Charge -1

This species takes part in two reactions (as a reactant in R SOTA and as a product in R SADH).

d M sucorn c = v − v (2774) dt 892 917

7.725 Species M sucsal c

Name Succinic semialdehyde

Charge -1

This species takes part in ﬁve reactions (as a reactant in R SHCHCS, R SSALx, R SSALy and as a product in R ABTA, R OXGDC).

d M sucsal c = v + v − v − v − v (2775) dt 8 735 905 920 921

7.726 Species M tamhexc c

Name tetra-methyl hexacosanoate

Charge -1

This species takes part in two reactions (as a reactant in R FASm2802 and as a product in R- FASm2602).

d M tamhexc c = v − v (2776) dt 391 394

1046 Produced by SBML2LATEX 7.727 Species M tamlgnc c

Name tri-methyl lignoceric acid

Charge -1

This species takes part in two reactions (as a reactant in R FASm2401 and as a product in R- FASm2201).

d M tamlgnc c = v − v (2777) dt 384 387

7.728 Species M tamocta c

Name tetra-methyl octacosanoate

Charge -1

This species takes part in three reactions (as a reactant in R PDIMAS, R PPDIMAS and as a product in R FASm280).

d M tamocta c = v − 2v − 2v (2778) dt 392 762 816

7.729 Species M tarab DASH D c

Name tetra-arabinofuranoside

Charge 0

This species takes part in two reactions (as a reactant in R ARABF and as a product in R TAS).

d M tarab DASH D c = v − 12v (2779) dt 932 91

7.730 Species M tartr DASH L c

Name L-tartrate

Charge -2

This species takes part in two reactions (as a reactant in R TARTD and as a product in R TARTRt7).

d M tartr DASH L c = v − v (2780) dt 931 930

Produced by SBML2LATEX 1047 7.731 Species M tartr DASH L e

Name L-tartrate

Charge -2

This species takes part in two reactions (as a reactant in R EX tartr DASH L e, R TARTRt7).

d M tartr DASH L e = −v − v (2781) dt 334 931

7.732 Species M tat c

Name tetra-acyl trehalose

Charge 0

This species takes part in two reactions (as a reactant in R biomass Mtb 9 60atp and as a product in R TATS).

d M tat c = v − 0.001176v (2782) dt 933 1025

7.733 Species M tcynt c

Name Thiocyanate

Charge -1

This species takes part in two reactions (as a product in R CYANST, R THSFST).

d M tcynt c = v + v (2783) dt 171 949

7.734 Species M tdcoa c

Name Tetradecanoyl-CoA (n-C14:0CoA)

Charge -4

This species takes part in two reactions (as a reactant in R FACOAE140 and as a product in R- FACOAL140).

d M tdcoa c = v − v (2784) dt 346 343

1048 Produced by SBML2LATEX 7.735 Species M tdm1 c

Name trehalose dimycolate (alpha mycolate + methoxymycolate)

Charge 0

This species takes part in four reactions (as a reactant in R TMHAS1, R TMHAS2, R TMHAS3 and as a product in R TDMS1).

d M tdm1 c = v − v − v − v (2785) dt 935 957 958 959

7.736 Species M tdm2 c

Name trehalose dimycolate (alpha mycolate + methoxymycolate)

Charge 0

This species takes part in four reactions (as a reactant in R TMHAS1, R TMHAS4, R TMHAS5 and as a product in R TDMS2).

d M tdm2 c = v − v − v − v (2786) dt 936 957 960 961

7.737 Species M tdm3 c

Name trehalose dimycolate (alpha mycolate + ketomycolate)

Charge 0

This species takes part in four reactions (as a reactant in R TMHAS2, R TMHAS4, R TMHAS6 and as a product in R TDMS3).

d M tdm3 c = v − v − v − v (2787) dt 937 958 960 962

7.738 Species M tdm4 c

Name trehalose dimycolate (alpha mycolate + methoxymycolate)

Charge 0

This species takes part in four reactions (as a reactant in R TMHAS3, R TMHAS5, R TMHAS6 and as a product in R TDMS4).

d M tdm4 c = v − v − v − v (2788) dt 938 959 961 962

Produced by SBML2LATEX 1049 7.739 Species M thdp c

Name 2,3,4,5-Tetrahydrodipicolinate

Charge -2

This species takes part in two reactions (as a reactant in R THDPS and as a product in R DHDPRy).

d M thdp c = v − v (2789) dt 219 943

7.740 Species M thf c

Name 5,6,7,8-Tetrahydrofolate

Charge -2

This species takes part in 13 reactions (as a reactant in R FTHFL, R GCC2, R GCCb, R GHMT2, R GLYCL, R THFGLUS and as a product in R AICART, R DHFR, R FMETTRS, R FTHFD, R GARFT, R METS, R MOHMT).

d M thf c = v + v + v + v + v + v + v dt 64 221 411 426 455 608 627 (2790) − v427 − v456 − v458 − v463 − v486 − v944

7.741 Species M thfglu c

Name Tetrahydrofolyl-[Glu](2)

Charge -3

This species takes part in one reaction (as a product in R THFGLUS).

d M thfglu c = v (2791) dt 944

7.742 Species M thm c

Name Thiamin

Charge 1

This species takes part in two reactions (as a reactant in R TMN and as a product in R THMDP).

d M thm c = v − v (2792) dt 945 963

1050 Produced by SBML2LATEX 7.743 Species M thmmp c

Name Thiamin monophosphate

Charge -1

This species takes part in two reactions (as a reactant in R TMPKr and as a product in R TMPPP).

d M thmmp c = v − v (2793) dt 965 964

7.744 Species M thmpp c

Name Thiamine diphosphate

Charge -2

This species takes part in four reactions (as a reactant in R OXGDC2, R THMDP and as a product in R SHCHCS2, R TMPKr).

d M thmpp c = v + v − v − v (2794) dt 906 964 736 945

7.745 Species M thr DASH L c

Name L-Threonine

Charge 0

This species takes part in ﬁve reactions (as a reactant in R MCBTS, R THRD Lr, R biomass Mtb- 9 60atp and as a product in R THRS, R THRt2r).

d M thr DASH L c = v + v − v − v − 0.135712v (2795) dt 947 948 593 946 1025

7.746 Species M thr DASH L e

Name L-Threonine

Charge 0

This species takes part in two reactions (as a reactant in R EX thr DASH L e, R THRt2r).

d M thr DASH L e = −v − v (2796) dt 335 948

Produced by SBML2LATEX 1051 7.747 Species M thym c

Name Thymine

Charge 0

This species takes part in one reaction (as a product in R TMDPP).

d M thym c = v (2797) dt 955

7.748 Species M thymd c

Name Thymidine

Charge 0

This species takes part in three reactions (as a reactant in R TMDK1, R TMDPP and as a product in R NTD5).

d M thymd c = v − v − v (2798) dt 703 954 955

7.749 Species M tmbhn c

Name tri-methyl behenic acid

Charge -1

This species takes part in two reactions (as a reactant in R FASm2201 and as a product in R- FASm2001).

d M tmbhn c = v − v (2799) dt 381 384

7.750 Species M tmha1 c

Name tetramycolyl hexaarabinoside (tdm1 + tdm2 +tre) (Mtb)

Charge 0

This species takes part in two reactions (as a reactant in R biomass Mtb 9 60atp and as a product in R TMHAS1).

d M tmha1 c = v − 0.001106v (2800) dt 957 1025

1052 Produced by SBML2LATEX 7.751 Species M tmha2 c

Name tetramycolyl hexaarabinoside (tdm1 + tdm3 + tre) (Mtb)

Charge 0

This species takes part in two reactions (as a reactant in R biomass Mtb 9 60atp and as a product in R TMHAS2).

d M tmha2 c = v − 0.0011v (2801) dt 958 1025

7.752 Species M tmha3 c

Name tetramycolyl hexaarabinoside (tdm1 + tdm4 + tre) (Mtb)

Charge 0

This species takes part in two reactions (as a reactant in R biomass Mtb 9 60atp and as a product in R TMHAS3).

d M tmha3 c = v − 0.001104v (2802) dt 959 1025

7.753 Species M tmha4 c

Name tetramycolyl hexaarabinoside (tdm2 + tdm3 + tre) (Mtb)

Charge 0

This species takes part in two reactions (as a reactant in R biomass Mtb 9 60atp and as a product in R TMHAS4).

d M tmha4 c = v − 0.001097v (2803) dt 960 1025

7.754 Species M tmha5 c

Name tetramycolyl hexaarabinoside (tdm2 + tdm4 + tre) (Mtb)

Charge 0

This species takes part in one reaction (as a product in R TMHAS5).

d M tmha5 c = v (2804) dt 961

Produced by SBML2LATEX 1053 7.755 Species M tmha6 c

Name tetramycolyl hexaarabinoside (tdm3 + tdm4 + tre) (Mtb)

Charge 0

This species takes part in one reaction (as a product in R TMHAS6).

d M tmha6 c = v (2805) dt 962

7.756 Species M tmhexc c

Name tri-methyl hexacosanoate

Charge -1

This species takes part in two reactions (as a reactant in R FASm280 and as a product in R- FASm260).

d M tmhexc c = v − v (2806) dt 389 392

7.757 Species M tmlgnc c

Name tri-methyl lignoceric acid

Charge -1

This species takes part in four reactions (as a reactant in R FASm2602, R PATS, R TRIATS and as a product in R FASm2402).

d M tmlgnc c = v − v − 4v − v (2807) dt 388 391 747 972

7.758 Species M trdox c

Name Oxidized thioredoxin

Charge 0

This species takes part in nine reactions (as a reactant in R TRDR and as a product in R METSOXR1, R METSOXR2, R PAPR, R RNDR1, R RNDR2, R RNDR3, R RNDR4, R RNTR4).

d M trdox c = v + v + v + v + v + v + v + v − v (2808) dt 609 610 746 882 883 884 885 886 967

1054 Produced by SBML2LATEX 7.759 Species M trdrd c Name Reduced thioredoxin

Charge 0

This species takes part in nine reactions (as a reactant in R METSOXR1, R METSOXR2, R PAPR, R RNDR1, R RNDR2, R RNDR3, R RNDR4, R RNTR4 and as a product in R TRDR). d M trdrd c = v − v − v − v − v − v − v − v − v (2809) dt 967 609 610 746 882 883 884 885 886

7.760 Species M tre6p c Name alpha,alpha’-Trehalose 6-phosphate

Charge -2

This species takes part in three reactions (as a reactant in R TRE6PP, R biomass Mtb 9 60atp and as a product in R TRE6PS). d M tre6p c = v − v − 0.006491v (2810) dt 969 968 1025

7.761 Species M tre c Name Trehalose

Charge 0

This species takes part in 19 reactions (as a reactant in R MTI, R PATS, R TATS, R TDMS1, R- TDMS2, R TDMS3, R TDMS4, R TMHAS1, R TMHAS2, R TMHAS3, R TMHAS4, R TMHAS5, R TMHAS6, R TRESULT, R TRIATS, R biomass Mtb 9 60atp and as a product in R MOTH, R TRE6PP, R- TREabc).

d M tre c = v + v + v − v − v − v − v − v − v − v dt 628 968 971 639 747 933 935 936 937 938 (2811) − v957 − v958 − v959 − v960 − v961 − v962 − v970 − v972 − 0.00797v1025

7.762 Species M tre e Name Trehalose

Charge 0

This species takes part in two reactions (as a reactant in R EX tre e, R TREabc). d M tre e = −v − v (2812) dt 336 971

Produced by SBML2LATEX 1055 7.763 Species M tres c

Name trehalose 2 sulfate

Charge -1

This species takes part in three reactions (as a reactant in R TATSO, R biomass Mtb 9 60atp and as a product in R TRESULT).

d M tres c = v − v − 0.006474v (2813) dt 970 934 1025

7.764 Species M triat c

Name tri-acyl trehalose

Charge 0

This species takes part in one reaction (as a product in R TRIATS).

d M triat c = v (2814) dt 972

7.765 Species M trnaala c

Name tRNA(Ala)

Charge 0

This species takes part in one reaction (as a reactant in R ALATRS).

d M trnaala c = −v (2815) dt 75

7.766 Species M trnaglu c

Name tRNA (Glu)

Charge 0

This species takes part in one reaction (as a product in R GLUTRR).

d M trnaglu c = v (2816) dt 480

1056 Produced by SBML2LATEX 7.767 Species M trp DASH L c

Name L-Tryptophan

Charge 0

This species takes part in ﬁve reactions (as a reactant in R TRPTA, R biomass Mtb 9 60atp and as a product in R TRPS1, R TRPS2, R TRPt2r).

d M trp DASH L c = v + v + v − v − 0.020124v (2817) dt 973 974 977 976 1025

7.768 Species M trp DASH L e

Name L-Tryptophan

Charge 0

This species takes part in two reactions (as a reactant in R EX trp DASH L e, R TRPt2r).

d M trp DASH L e = −v − v (2818) dt 337 977

7.769 Species M tsul c

Name Thiosulfate

Charge -2

This species takes part in three reactions (as a reactant in R CYANST, R THSFST and as a product in R TSULabc).

d M tsul c = v − v − v (2819) dt 978 171 949

7.770 Species M tsul e

Name Thiosulfate

Charge -2

This species takes part in two reactions (as a reactant in R EX tsul e, R TSULabc).

d M tsul e = −v − v (2820) dt 338 978

Produced by SBML2LATEX 1057 7.771 Species M ttc c

Name tetracosanoate (n-C24:0)

Charge -1

This species takes part in two reactions (as a reactant in R FAS260 and as a product in R FAS240- L).

d M ttc c = v − v (2821) dt 374 375

7.772 Species M ttdca c

Name tetradecanoate (n-C14:0)

Charge -1

This species takes part in eight reactions (as a reactant in R FACOAL140, R FAO1, R FAS160, R- FAS161, R biomass Mtb 9 60atp and as a product in R FACOAE140, R FAS140, R TTDCAt2).

d M ttdca c = v + v + v − v − v − v − v − 0.012193v (2822) dt 343 368 979 346 361 369 370 1025

7.773 Species M ttdca e

Name tetradecanoate (n-C14:0)

Charge -1

This species takes part in two reactions (as a reactant in R EX ttdca e, R TTDCAt2).

d M ttdca e = −v − v (2823) dt 339 979

7.774 Species M tyr DASH L c

Name L-Tyrosine

Charge 0

This species takes part in ﬁve reactions (as a reactant in R THZPSN, R THZSN, R TYRTA, R- biomass Mtb 9 60atp and as a product in R TYRt2r).

d M tyr DASH L c = v − v − v − v − 0.031756v (2824) dt 981 950 951 980 1025

1058 Produced by SBML2LATEX 7.775 Species M tyr DASH L e

Name L-Tyrosine

Charge 0

This species takes part in two reactions (as a reactant in R EX tyr DASH L e, R TYRt2r).

d M tyr DASH L e = −v − v (2825) dt 340 981

7.776 Species M uAgl c

Name UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine

Charge -3

This species takes part in two reactions (as a reactant in R UGLDDS1 and as a product in R- UAAGLS1).

d M uAgl c = v − v (2826) dt 983 1003

7.777 Species M uAgla c

Name UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine

Charge -3

This species takes part in two reactions (as a reactant in R PAPPT1 and as a product in R- UGLDDS1).

d M uAgla c = v − v (2827) dt 1003 743

7.778 Species M uGgl c

Name UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysine

Charge -3

This species takes part in two reactions (as a reactant in R UGLDDS2 and as a product in R- UAAGLS2).

d M uGgl c = v − v (2828) dt 984 1004

Produced by SBML2LATEX 1059 7.779 Species M uGgla c

Name UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine

Charge -3

This species takes part in two reactions (as a reactant in R PAPPT2 and as a product in R- UGLDDS2).

d M uGgla c = v − v (2829) dt 1004 744

7.780 Species M uaAgla c

Name Undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine

Charge -3

This species takes part in two reactions (as a reactant in R UAGPT1 and as a product in R PAPPT1).

d M uaAgla c = v − v (2830) dt 743 987

7.781 Species M uaGgla c

Name Undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl- D-alanine

Charge -3

This species takes part in two reactions (as a reactant in R UAGPT2 and as a product in R PAPPT2).

d M uaGgla c = v − v (2831) dt 744 988

7.782 Species M uaaAgla c

Name Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-glutamyl- L-lysyl-D-alanyl-D-alanine

Charge -3

This species takes part in four reactions (as a reactant in R GLNSP1, R PPTGS TB1, R biomass- Mtb 9 60atp and as a product in R UAGPT1).

d M uaaAgla c = v − v − v − 0.001008v (2832) dt 987 470 828 1025

1060 Produced by SBML2LATEX 7.783 Species M uaaAgtla c Name Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-glutaminyl- L-lysyl-D-alanyl-D-alanine

Charge -2

This species takes part in one reaction (as a product in R GLNSP1). d M uaaAgtla c = v (2833) dt 470

7.784 Species M uaaGgla c Name Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-gamma-D- glutamyl-L-lysyl-D-alanyl-D-alanine

Charge -3

This species takes part in four reactions (as a reactant in R GLNSP2, R PPTGS TB2, R biomass- Mtb 9 60atp and as a product in R UAGPT2). d M uaaGgla c = v − v − v − 0.001008v (2834) dt 988 471 829 1025

7.785 Species M uaaGgtla c Name Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-isoglutaminyl- L-lysyl-D-alanyl-D-alanine

Charge -2

This species takes part in one reaction (as a product in R GLNSP2). d M uaaGgtla c = v (2835) dt 471

7.786 Species M uaagmda c Name Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-ala-D-glu-meso- 2,6-diaminopimeloyl-D-ala-D-ala

Charge -4

This species takes part in four reactions (as a reactant in R GLNSP3, R PPTGS, R biomass Mtb- 9 60atp and as a product in R UAGPT3). d M uaagmda c = v − v − v − 9.86 · 10−4v (2836) dt 989 472 827 1025

Produced by SBML2LATEX 1061 7.787 Species M uaagtmda c

Name Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-glutaminyl- meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

Charge -3

This species takes part in one reaction (as a product in R GLNSP3).

d M uaagtmda c = v (2837) dt 472

7.788 Species M uaccg c

Name UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-glucosamine

Charge -3

This species takes part in two reactions (as a reactant in R UAPGR and as a product in R UAGCVT).

d M uaccg c = v − v (2838) dt 985 993

7.789 Species M uacgam c

Name UDP-N-acetyl-D-glucosamine

Charge -2

This species takes part in seven reactions (as a reactant in R ACGAMT, R UAGCVT, R UAGPT1, R UAGPT2, R UAGPT3, R UGGPT3 and as a product in R UAGDP).

d M uacgam c = v − v − v − v − v − v − v (2839) dt 986 17 985 987 988 989 1002

7.790 Species M uagmda c

Name Undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl- D-alanyl-D-alanine

Charge -4

This species takes part in two reactions (as a reactant in R UAGPT3 and as a product in R PAPPT3).

d M uagmda c = v − v (2840) dt 745 989

1062 Produced by SBML2LATEX 7.791 Species M uama c

Name UDP-N-acetylmuramoyl-L-alanine

Charge -3

This species takes part in two reactions (as a reactant in R UAMAGS and as a product in R UAMAS).

d M uama c = v − v (2841) dt 991 990

7.792 Species M uamag c

Name UDP-N-acetylmuramoyl-L-alanyl-D-glutamate

Charge -4

This species takes part in four reactions (as a reactant in R UAAGDS, R UAAGLS1, R UAAGLS2 and as a product in R UAMAGS).

d M uamag c = v − v − v − v (2842) dt 990 982 983 984

7.793 Species M uamr c

Name UDP-N-acetylmuramate

Charge -3

This species takes part in four reactions (as a reactant in R UAMAS, R UAMRH, R biomass Mtb- 9 60atp and as a product in R UAPGR).

d M uamr c = v − v − v − 0.002793v (2843) dt 993 991 992 1025

7.794 Species M udcpdp c

Name Undecaprenyl diphosphate

Charge -3

This species takes part in seven reactions (as a reactant in R UDCPDP and as a product in R PPTGS, R PPTGS TB1, R PPTGS TB2, R UDCPDPS, R UDPDPS, R UDPDPS2).

d M udcpdp c = v + v + v + v + v + v − v (2844) dt 827 828 829 995 996 997 994

Produced by SBML2LATEX 1063 7.795 Species M udcpp c Name Undecaprenyl phosphate

Charge -2

This species takes part in six reactions (as a reactant in R ACGAMT, R PAPPT1, R PAPPT2, R- PAPPT3, R PGPPT3 and as a product in R UDCPDP). d M udcpp c = v − v − v − v − v − v (2845) dt 994 17 743 744 745 782

7.796 Species M udp c Name UDP

Charge -3

This species takes part in eleven reactions (as a reactant in R NDPK2, R RNDR4 and as a product in R GALFT, R HMPK3, R TRE6PS, R UAGPT1, R UAGPT2, R UAGPT3, R UGGPT3, R UMPK, R- URIDK1). d M udp c = 30v + v + v + v + v + v + v + v + v − v − v dt 449 530 969 987 988 989 1002 1009 1016 677 885 (2846)

7.797 Species M udpg c Name UDPglucose

Charge -2

This species takes part in four reactions (as a reactant in R TRE6PS, R UDPG4E, R UDPGD and as a product in R GALUi). d M udpg c = v − v − v − v (2847) dt 452 969 998 1000

7.798 Species M udpgal c Name UDPgalactose

Charge -2

This species takes part in three reactions (as a reactant in R UDPGALM and as a product in R GALT, R UDPG4E). d M udpgal c = v + v − v (2848) dt 451 998 999

1064 Produced by SBML2LATEX 7.799 Species M udpgalfur c

Name UDP-D-galacto-1,4-furanose

Charge -2

This species takes part in two reactions (as a reactant in R GALFT and as a product in R UDPGALM).

d M udpgalfur c = v − 30v (2849) dt 999 449

7.800 Species M udpglcur c

Name UDP-D-glucuronate

Charge -3

This species takes part in one reaction (as a product in R UDPGD).

d M udpglcur c = v (2850) dt 1000

7.801 Species M ugagmda c

Name Undecaprenyl-diphospho-N-glycolylmuramoyl-(N-acetylglucosamine)-L-ala-D-glu-meso- 2,6-diaminopimeloyl-D-ala-D-ala

Charge -4

This species takes part in two reactions (as a reactant in R biomass Mtb 9 60atp and as a product in R UGGPT3).

d M ugagmda c = v − 9.77 · 10−4v (2851) dt 1002 1025

7.802 Species M ugggmda c

Name Undecaprenyl-diphospho-N-glycolylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl- D-alanyl-D-alanine

Charge -4

This species takes part in two reactions (as a reactant in R UGGPT3 and as a product in R PGPPT3).

d M ugggmda c = v − v (2852) dt 782 1002

Produced by SBML2LATEX 1065 7.803 Species M uggmd c

Name UDP-N-glycolylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminopimelate

Charge -4

This species takes part in two reactions (as a reactant in R UGMDDS2 and as a product in R- UGAGDS).

d M uggmd c = v − v (2853) dt 1001 1008

7.804 Species M uggmda c

Name UDP-N-glycolylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D- alanine

Charge -4

This species takes part in two reactions (as a reactant in R PGPPT3 and as a product in R- UGMDDS2).

d M uggmda c = v − v (2854) dt 1008 782

7.805 Species M ugma c

Name UDP-N-glycolylmuramoyl-L-alanine

Charge -3

This species takes part in two reactions (as a reactant in R UGMAGS and as a product in R UGMAS).

d M ugma c = v − v (2855) dt 1006 1005

7.806 Species M ugmag c

Name UDP-N-glycolylmuramoyl-L-alanyl-D-glutamate

Charge -4

This species takes part in two reactions (as a reactant in R UGAGDS and as a product in R UGMAGS).

d M ugmag c = v − v (2856) dt 1005 1001

1066 Produced by SBML2LATEX 7.807 Species M ugmd c

Name UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminopimelate

Charge -4

This species takes part in two reactions (as a reactant in R UGMDDS and as a product in R UAAGDS).

d M ugmd c = v − v (2857) dt 982 1007

7.808 Species M ugmda c

Name UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

Charge -4

This species takes part in two reactions (as a reactant in R PAPPT3 and as a product in R UGMDDS).

d M ugmda c = v − v (2858) dt 1007 745

7.809 Species M ugmr c

Name UDP-N-glycolylmuramate

Charge -3

This species takes part in two reactions (as a reactant in R UGMAS and as a product in R UAMRH).

d M ugmr c = v − v (2859) dt 992 1006

7.810 Species M ump c

Name UMP

Charge -2

This species takes part in 13 reactions (as a reactant in R NTD2, R UMPK, R URIDK1, R biomass- Mtb 9 60atp and as a product in R ACGAMT, R NTPP8, R OMPDC, R PAPPT1, R PAPPT2, R- PAPPT3, R PGPPT3, R UPPRT, R URIK2).

d M ump c = v + v + v + v + v + v + v + v dt 17 713 727 743 744 745 782 1014 (2860) + v1018 − v700 − v1009 − v1016 − 0.131604v1025

Produced by SBML2LATEX 1067 7.811 Species M unaga c

Name Undecaprenyl diphospho N-acetyl-glucosamine

Charge -2

This species takes part in two reactions (as a reactant in R O16RHAT and as a product in R- ACGAMT).

d M unaga c = v − v (2861) dt 17 719

7.812 Species M uppg1 c

Name Uroporphyrinogen I

Charge -8

This species takes part in one reaction (as a reactant in R UPPDC2).

d M uppg1 c = −v (2862) dt 1013

7.813 Species M uppg3 c

Name Uroporphyrinogen III

Charge -8

This species takes part in three reactions (as a reactant in R UPP3MT, R UPPDC1 and as a product in R UPP3S).

d M uppg3 c = v − v − v (2863) dt 1011 1010 1012

7.814 Species M ura c

Name Uracil

Charge 0

This species takes part in three reactions (as a reactant in R UPPRT, R YUMPS and as a product in R DURIPP).

d M ura c = v − v − v (2864) dt 248 1014 1024

1068 Produced by SBML2LATEX 7.815 Species M urea c

Name Urea

Charge 0

This species takes part in two reactions (as a reactant in R UREA and as a product in R AGMT).

d M urea c = v − v (2865) dt 56 1015

7.816 Species M uri c

Name Uridine

Charge 0

This species takes part in three reactions (as a reactant in R URIK2 and as a product in R CYTD, R NTD2).

d M uri c = v + v − v (2866) dt 182 700 1018

7.817 Species M utp c

Name UTP

Charge -4

This species takes part in ten reactions (as a reactant in R CTPS1, R CTPS2, R GALT, R GALUi, R HMPK3, R NTPP8, R RNTR4, R UAGDP and as a product in R DCTPD2, R NDPK2).

d M utp c = v + v − v − v − v − v − v − v − v − v (2867) dt 210 677 169 170 451 452 530 713 886 986

7.818 Species M val DASH L c

Name L-Valine

Charge 0

This species takes part in three reactions (as a reactant in R VALTA, R biomass Mtb 9 60atp and as a product in R VALt2r).

d M val DASH L c = v − v − 0.205827v (2868) dt 1020 1019 1025

Produced by SBML2LATEX 1069 7.819 Species M val DASH L e

Name L-Valine

Charge 0

This species takes part in two reactions (as a reactant in R EX val DASH L e, R VALt2r).

d M val DASH L e = −v − v (2869) dt 341 1020

7.820 Species M xan c

Name Xanthine

Charge 0

This species takes part in three reactions (as a reactant in R XPPT and as a product in R GUAD, R PUNP7).

d M xan c = v + v − v (2870) dt 512 863 1021

7.821 Species M xmp c

Name Xanthosine 5’-phosphate

Charge -2

This species takes part in four reactions (as a reactant in R GMPS2, R NTD10 and as a product in R IMPD, R XPPT).

d M xmp c = v + v − v − v (2871) dt 554 1021 495 698

7.822 Species M xtsn c

Name Xanthosine

Charge 0

This species takes part in two reactions (as a reactant in R PUNP7 and as a product in R NTD10).

d M xtsn c = v − v (2872) dt 698 863

1070 Produced by SBML2LATEX 7.823 Species M xu5p DASH D c Name D-Xylulose 5-phosphate

Charge -2

This species takes part in four reactions (as a reactant in R TKT1, R TKT2 and as a product in R RPE, R XYLK). d M xu5p DASH D c = v + v − v − v (2873) dt 887 1022 952 953

7.824 Species M xyl DASH D c Name D-Xylose

Charge 0

This species takes part in one reaction (as a product in R XYLabc). d M xyl DASH D c = v (2874) dt 1023

7.825 Species M xyl DASH D e Name D-Xylose

Charge 0

This species takes part in two reactions (as a reactant in R EX xyl DASH D e, R XYLabc). d M xyl DASH D e = −v − v (2875) dt 342 1023

7.826 Species M xylu DASH D c Name D-Xylulose

Charge 0

This species takes part in one reaction (as a reactant in R XYLK). d M xylu DASH D c = −v (2876) dt 1022

A Glossary of Systems Biology Ontology Terms

SBO:0000625 Unknown SBO id 625: Unknown SBO id 625

SBO:0000626 Unknown SBO id 626: Unknown SBO id 626

Produced by SBML2LATEX 1071 a a a SBML2LATEX was developed by Andreas Drager¨ , Hannes Planatscher , Dieudonne´ M Wouamba , Adrian Schroder¨ a, Michael Huckab, Lukas Endlerc, Martin Golebiewskid and Andreas Zella. Please see http: //www.ra.cs.uni-tuebingen.de/software/SBML2LaTeX for more information.

aCenter for Bioinformatics Tubingen¨ (ZBIT), Germany bCalifornia Institute of Technology, Beckman Institute BNMC, Pasadena, United States cEuropean Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom dEML Research gGmbH, Heidelberg, Germany

1072 Produced by SBML2LATEX