DOCSLIB.ORG

Service Juridique – Juridische Dienst Coordination Officieuse

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Service Juridique – Juridische Dienst Coordination Officieuse Coordination officieuse de l’arrêté royal du 22 Officieuze coördinatie van het Koninklijk besluit JANVIER 1998 réglementant certaines substances van 22 januari 1998 tot houdende regeling van psychotropes, et relatif à la réduction des risques sommige psychotrope stoffen en betreffende et à l'avis thérapeutique avec l’Arrêté royal du risicobeperking en therapeutisch advies met het 25 novembre 2015. (M.B. 10.12.2015) Koninklijk besluit van 25 november 2015 (B.S. 10.12.2015) CHAPITRE I. HOOFDSTUK I. Article 1. Pour l'application du présent arrêté, Artikel 1. Voor de toepassing van dit besluit on entend par : wordt verstaan onder : 1) "substances psychotropes" : les substances 1) "psychotrope stoffen" : de stoffen bedoeld visées aux articles 2, 25 et 38 du présent bij de artikelen 2, 25 en 38 van dit besluit, arrêté, leurs sels et les préparations hun zouten en de bereidingen waarin deze contenant ces substances ou leurs sels; stoffen of hun zouten verwerkt zijn; 1) « substances psychotropes » : 1) "psychotrope stoffen" : -les substances visées aux articles 2, 25 et 38 -de stoffen bedoeld bij de artikelen 2, 25 en 38 du présent arrêté, leurs stéréo-isomères (à van dit besluit, de stereo-isomeren van deze l'exception de ceux de la cathine), leurs sels, en stoffen (uitgezonderd deze van cathine), de ce compris les sels des stéréo-isomères, dans le zouten van deze stoffen, met inbegrip van de cas où ces stéréo-isomères et sels peuvent zouten van de stereo- isomeren, in het geval exister d'un point de vue chimique. waar die stereo-isomeren en zouten scheikundig kunnen bestaan. - Les préparations contenant ces substances, - De bereidingen waarin deze stoffen, stereo- stéréo-isomères ou leurs sels; isomeren, of hun zouten verwerkt zijn;" 2) "Service des stupéfiants" : la section de 2) "Dienst der verdovende middelen" : de l'Inspection générale de la Pharmacie chargée de afdeling van de Algemene Farmaceutische l'application des dispositions de la loi du 24 Inspectie belast met de toepassing van de février 1921 concernant le trafic des substances bepalingen van de wet van 24 februari 1921 vénéneuses, soporifiques, stupéfiantes, betreffende het verhandelen van giftstoffen, désinfectantes ou antiseptiques et de ses arrêtés slaapmiddelen en verdovende middelen, d'exécution, lorsqu'elles concernent des ontsmettingsstoffen en antiseptica en van haar stupéfiants et substances psychotropes; uitvoeringsbesluiten wanneer deze betrekking hebben op verdovende middelen en psychotrope stoffen; 3) "importation" : l'introduction sur le territoire 3) "invoer" : het op het nationaal grondgebied national de substances psychotropes destinées à binnenbrengen van psychotrope stoffen une personne physique ou morale établie dans le bestemd voor een fysisch of rechtspersoon die pays, ci-après dénommée importateur; in het land is gevestigd, hierna genoemd de invoerder; 4) "exportation" : la sortie du territoire national 4) "uitvoer" : het verlaten van het nationaal de substances psychotropes au départ d'un grondgebied van psychotrope stoffen uitgaande bureau des douanes, d'un entrepôt douanier ou van een douanebureau, een douane-entrepot of des installations d'une personne physique ou de installaties van een fysisch of rechtspersoon morale établie dans le pays, ci-après dénommée die in het land is gevestigd, hierna genoemd de exportateur; uitvoerder; 5) "autorisation d'importation" : document 5) "invoervergunning" : een document, délivré par le Ministre qui a la Santé publique afgeleverd door de Minister die de dans ses attributions permettant l'importation Volksgezondheid onder zijn bevoegdheid heeft, APB – Service Juridique – Juridische Dienst de substances psychotropes; dat de invoer van psychotrope stoffen toelaat; 6) "autorisation d'exportation" : selon le cas : 6) "uitvoervergunning" : naargelang het geval : - document délivré par le Ministre qui a la Santé - een document afgeleverd door de Minister publique dans ses attributions permettant die de Volksgezondheid onder zijn bevoegdheid l'exportation de substances psychotropes, ou heeft, dat de uitvoer van psychotrope stoffen toelaat, of - document délivré par l'autorité compétente - een document afgeleverd door de bevoegde d'un pays exportateur permettant la livraison de autoriteiten van een uitvoerland, dat de levering substances psychotropes à une personne toelaat van psychotrope stoffen aan een fysisch physique ou morale établie à l'extérieur de ce of rechtspersoon, gevestigd buiten dat land; pays; 7) "transit" : la circulation à travers le territoire 7) "doorvoer" : het verkeer doorheen het national ainsi que le séjour en dépôt temporaire nationaal grondgebied alsook het verblijf in avant réexportation de substances psychotropes; tijdelijke opslag voorafgaand aan de wederuitvoer van psychotrope stoffen; 8) "Ministre" : le Ministre qui a la Santé 8) "Minister" : de Minister die de publique dans ses attributions. Volksgezondheid onder zijn bevoegdheid heeft. CHAPITRE II. HOOFDSTUK II. Art. 2. § 1er. Les dispositions du chapitre II du Art. 2. § 1. De bepalingen van hoofdstuk II van présent arrêté sont applicables aux substances dit besluit zijn van toepassing op de psychotropes suivantes (et à leurs stéréo- hiernavolgende psychotrope stoffen (en op hun isomères) : stereo-isomeren) : a) BROLAMFETAMINE (DOB); a) BROLAMFETAMINE (DOB); CATHINONE; CATHINONE; DET (((diéthylamino)-2 éthyl)-3 indole); DET (3-(2-(diethylamino)ethyl)indole); DMA ((+/-)-diméthoxy-2,5 alpha- DMA ((+)-2,5-dimethoxy-alpha- méthylphénéthylamine); methylphenethylamine); DMHP ((diméthyl-1,2 heptyl)-3 tétrahydro- DMHP (3-(1,2-dimethylheptyl)-7,8,9,10- 7,8,9,10 triméthyl-6,6,9 6H-dibenzo(b,d)pyranne tetrahydro-6,6,9-trimethyl-6H- ol-1); dibenzo(b,d)pyran-1-ol); DMT (((diméthylamino)-2 éthyl)-3 indole); DMT (3-(2-(dimethylamino)ethyl)indole); DOET ((+/-)-éthyl-4 diméthoxy-2,5 alpha- DOET ((+)-4-ethyl-2,5-dimethoxy-alpha- phénéthylamine); phenethylamine); ETICYCLIDINE (PCE); ETICYCLIDINE (PCE); ETRYPTAMINE; ETRYPTAMINE; (+)-LYSERGIDE (LSD, LSD-25); (+)-LYSERGIDE (LSD, LSD-25); MDMA ((+/-)-N,alpha-diméthyl MDMA ((+)-N,alpha-dimethyl-3,4- (méthylènedioxy)-3,4 phénéthylamine); (methylenedioxy)phenethylamine); MESCALINE (triméthoxy-3,4,5 phénéthylamine); MESCALINE (3,4,5-trimethoxyphenethylamine); METHCATHINONE (2-(méthylamino)-1- METHCATHINONE (methylamino-2- phénylpropan-1-one); phenylpropaan-1-on); METHYL-4 AMINOREX ((+/-)-cis-amino-2 méthyl- 4-METHYLAMINOREX ((+)-cis-2-amino-4- 4 phényl-5 oxazoline-2); methyl-5-phenyl-2-oxazoline); MMDA (méthoxy-2 alpha-méthyl MMDA (2-methoxy-alpha-methyl-4,5- (méthylènedioxy)-4,5 phénéthylamine); (methylenedioxy)phenethylamine); N-ETHYL MDA ((+/-)-N-éthyl-alpha-méthyl N-ETHYL MDA ((+)-N-ethyl-alpha-methyl-3,4- (méthylènedioxy)-3,4 phénéthylamine); (methylenedioxy)phenethylamine); N-HYDROXY MDA ((+/-)-N-(alpha-méthyl N-HYDROXY MDA ((+)-N-(alpha-methyl-3,4- APB – Service Juridique – Juridische Dienst (méthylènedioxy)-3,4 phénéthyl)hydroxylamine); (methylenedioxy)phenethyl)hydroxylamine); PARAHEXYL (hexyl-3 tétrahydro-7,8,9,10 PARAHEXYL (3-hexyl-7,8,9,10-tetrahydro-6,6,9- triméthyl-6,6,9 6H-dibenzo(b,d)pyranne ol-1); trimethyl-6H-dibenzo(b,d)pyran-1-ol); PMA (p-méthoxy alpha- PMA (p-methoxy-alpha- méthylphénéthylamine); methylphenethylamine); PSILOCINE (psilotsin ou ((dimethyl-amino)-2 PSILOCINE (psilotsin of 3-(2-(dimethyl- éthyl)-3 indole-4-ol); amino)ethyl)indol-4-ol); PSILOCYBINE; PSILOCYBINE; ROLICYCLIDINE (PHP, PCPY); ROLICYCLIDINE (PHP, PCPY); STP (DOM); STP (DOM); TENAMFETAMINE (MDA); TENAMFETAMINE (MDA); TENOCYCLIDINE (TCP); TENOCYCLIDINE (TCP); TETRAHYDROCANNABINOL, les isomères TETRAHYDROCANNABINOL, volgende isomeren suivants et leurs variantes stéréochimiques : en hun stereochemische varianten : - tétrahydro-7,8,9,10 triméthyl-6,6,9 pentyl-3 - 7,8,9,10-tetrahydro-6,6,9-trimethyl-3-pentyl- 6H-dibenzo(b,d)pyranne ol-1; 6H-dibenzo(b,d)pyran-1-ol; - (9R,10aR)-tétrahydro-8,9,10,10a triméthyl- - (9R,10aR)-8,9,10,10a-tetrahydro-6,6,9- 6,6,9 pentyl-3 6H-dibenzo(b,d)pyranne ol-1; trimethyl-3-pentyl-6H-dibenzo(b,d)pyran-1-ol; - (6aR,9R,10aR)-tétrahydro-6a,9,10,10a - (6aR,9R,10aR)-6a,9,10,10a-tetrahydro-6,6,9- triméthyl-6,6,9 pentyl-3 6H-dibenzo(b,d)pyranne trimethyl-3-pentyl-6H-dibenzo (b,d)pyran-1-ol; ol-1; - (6aR,10aR)-6a,7,10,10a-tetrahydro-6,6,9- - (6aR,10aR)-tétrahydro-6a,7,10,10a triméthyl- trimethyl-3-pentyl-6H-dibenzo(b,d)pyran-1-ol; 6,6,9 pentyl-3 6H-dibenzo(b,d)pyranne ol-1; - 6a,7,8,9,-tetrahydro-6,6,9-trimethyl-3-pentyl- - tétrahydro-6a,7,8,9 triméthyl-6,6,9 pentyl-3 6H-dibenzo(b,d)pyran-1-ol; 6H-dibenzo(b,d)pyranne ol-1; - (6aR,10aR)-6a,7,8,9,10,10a-hexahydro-6,6- - (6aR,10aR)-hexahydro-6a,7,8,9,10,10a dimethyl-9-methylene-3-pentyl-6H- diméthyl-6,6 méthylène-9 pentyl-3 6H- dibenzo(b,d)pyran-1-ol; dibenzo(b,d)pyranne ol-1; TMA ((+)-3,4,5-trimethoxy-alpha- TMA ((+/-)-triméthoxy-3,4,5 alpha- methylphenethylamine); méthylphénéthylamine); - 25I-NBOMe [2-(4-iodo-2,5- - 25I-NBOMe :[2-(4-iodo-2,5- dimethoxyphenyl)ethyl][(2- dimethoxyphenyl)ethyl] methoxyphenyl)methyl]amine; [(2-methoxyphenyl)methyl]amine; - 25B-NBOMe [2-(4-bromo-2,5- - 25B-NBOMe : [2-(4-bromo-2,5- dimethoxyphenyl)ethyl][(2- dimethoxyphenyl)ethyl] methoxyphenyl)methyl]amine; [(2-methoxyphenyl)methyl]amine; - 25C-NBOMe [2-(4-chloro-2,5- - 25C-NBOMe : [2-(4-chloro-2,5- dimethoxyphenyl)ethyl][(2- dimethoxyphenyl)ethyl] methoxyphenyl)methyl]amine; [(2-methoxyphenyl)methyl]amine; - 4-MTA : 1-[4-(methylsulfanyl)phenyl]propan-2- - 4-MTA : 1-[4-(methylsulfanyl)phenyl]propan- amine 2-amine b) AMFETAMINE; b) AMFETAMINE; (AMINEPTINE) (AMINEPTINE)
Load more

Recommended publications
  • Supporting Information a Analysed Substances
    Electronic Supplementary Material (ESI) for Analyst. This journal is © The Royal Society of Chemistry 2020 List of contents: Tab. A1 Detailed list and classification of analysed substances. Tab. A2 List of selected MS/MS parameters for the analytes. Tab. A1 Detailed list and classification of analysed substances. drug of therapeutic doping agent analytical standard substance abuse drug (WADA class)* supplier (+\-)-amphetamine ✓ ✓ S6 stimulants LGC (+\-)-methamphetamine ✓ S6 stimulants LGC (+\-)-3,4-methylenedioxymethamphetamine (MDMA) ✓ S6 stimulants LGC methylhexanamine (4-methylhexan-2-amine, DMAA) S6 stimulants Sigma cocaine ✓ ✓ S6 stimulants LGC methylphenidate ✓ ✓ S6 stimulants LGC nikethamide (N,N-diethylnicotinamide) ✓ S6 stimulants Aldrich strychnine S6 stimulants Sigma (-)-Δ9-tetrahydrocannabinol (THC) ✓ ✓ S8 cannabinoids LGC (-)-11-nor-9-carboxy-Δ9-tetrahydrocannabinol (THC-COOH) S8 cannabinoids LGC morphine ✓ ✓ S7 narcotics LGC heroin (diacetylmorphine) ✓ ✓ S7 narcotics LGC hydrocodone ✓ ✓ Cerillant® oxycodone ✓ ✓ S7 narcotics LGC (+\-)-methadone ✓ ✓ S7 narcotics Cerillant® buprenorphine ✓ ✓ S7 narcotics Cerillant® fentanyl ✓ ✓ S7 narcotics LGC ketamine ✓ ✓ LGC phencyclidine (PCP) ✓ S0 non-approved substances LGC lysergic acid diethylamide (LSD) ✓ S0 non-approved substances LGC psilocybin ✓ S0 non-approved substances Cerillant® alprazolam ✓ ✓ LGC clonazepam ✓ ✓ Cerillant® flunitrazepam ✓ ✓ LGC zolpidem ✓ ✓ LGC VETRANAL™ boldenone (Δ1-testosterone / 1-dehydrotestosterone) ✓ S1 anabolic agents (Sigma-Aldrich)
    [Show full text]
  • January 2020 Sanctions List Full
    GLOBAL LIST OF INELIGIBLE PERSONS Period of Date of Discipline Date of Ineligibility Lifetime Infraction Name Nationality Role Sex Discipline 2 Sanction Disqualification ADRV Rules ADRV Notes Description Birth 1 Infraction until Ban? Type of results ABAKUMOVA, Maria 15/01/1986 RUS athlete F Javelin Throws 21/08/2008 4 years 17/05/2020 From 21.08.08 to No Doping Presence,Use Dehydrochloromethyltestos In competition test, XXIX Olympic ineligibility 20.08.12 terone games, Beijing, CHN ABDOSH, Ali 25/08/1987 ETH athlete M Long Distance 24/12/2017 4 years 04/02/2022 Since 24-12-2017 No Doping Presence,Use Salbutamol In competition test, 2017 Baoneng (3000m+) ineligibility Guangzhou Huangpu Marathon , ACHERKI, Mounir 09/02/1981 FRA athlete M 1500m Middle Distance 01/01/2014 4 years 15/04/2021 Since 01-01-2014 No Doping Use,Possessio Use or Attempted Use by an IAAF Rule 32.2(b) Use of a prohibited (800m-1500m) ineligibility n Athlete of a Prohibited substance ADAMCHUK, Mariya 29/05/2000 UKR athlete F Long Jump Jumps 03/06/2018 4 years 16/08/2022 Since 03.06.18 No Doping Presence,Use Benzoylecgonine In competition test, XXI Cross Citta ineligibility di Novi Ligure, Novi Ligure, ITA ADEKOYA, Kemi 16/01/1993 BRN athlete F 400m Sprints (400m or 24/08/2018 4 years 25/11/2022 Since 24.08.18 No Doping Presence,Use Stanozolol Out-of-competition test, Jakarta, IDN Hurdles less) ineligibility ADELOYE, Tosin 07/02/1996 NGR athlete F 400m Sprints (400m or 24/07/2015 8 years 23/07/2023 Since 24-07-2015 No Doping Presence,Use Exogenous Steroids In competition
    [Show full text]
  • CRIME AWARENESS BULLETIN Joint Base Lewis-Mcchord Directorate of Emergency Services Police Intelligence / Crime Analysis Unit
    CRIME AWARENESS BULLETIN Joint Base Lewis-McChord Directorate of Emergency Services Police Intelligence / Crime Analysis Unit 30 May 2012 Emerging Drug Trend First there was K2 (Spice) and the slew of synthetic cannabinoids. Then came bath salts; they were new and they were legal. These drugs were available and sold as over-the-counter products in an international web-based marketplace. Many of them were sold in head shops and medical marijuana clinics in the United States. But now these synthetics are all banned, well, most of them anyway. But into the fray now comes "Pump-It Powder," an "enhanced plant vitamin." It's the latest synthetic drug to be manufactured and sold under the ruse of a substance, "not intended for human consumption." With myriad bath salts and plant food products available in the marketplace, uncertainty already reigns. No one quite knows what is in these synthetics. The Internet is full of supposition, but it is not clear at all what manufacturers are putting into their final products. Nevertheless, a great deal of discussion has centered on the role of geranamine as primary constituent of Pump-It. Geranamine is also known as methylhexanamine, an old-time amphetamine-related stimulant and decongestant that is found naturally in the geranium plant, hence its name. Methylhexanamine is a legal substance; it is not scheduled by the DEA. The drug has not been widely studied. It was patented in 1944 and for the most part has been dormant since that time. But in the world of energy drinks and aphrodisiac potions, methylhexanamine has been a prime player.
    [Show full text]
  • Accidental Doping. Prevention Strategies
    RevisiónPedro Manonelles, et al. Accidental doping. Prevention strategies Pedro Manonelles1, Oriol Abellán Aynés2, Daniel López-Plaza2, Marta Fernández Calero3, Carmen Daniela Quero Calero1, Luis Andreu Caravaca1, José Luis Terreros4 1Cátedra Internacional de Medicina del Deporte. Universidad Católica San Antonio de Murcia (UCAM). 2Facultad de Deporte. Universidad Católica San Antonio de Murcia (UCAM). 3Facultad de Ciencias de la Salud. Universidad Católica San Antonio de Murcia (UCAM). 4Agencia Española de protección de la Salud en el Deporte (AEPSAD). Recibido: 30.10.2019 Summary Aceptado: 15.11.2019 There is growing consumption of nutritional supplements aimed at improving performance because the number of athletes, mainly amateurs, is growing very significantly. This great demand supposes a market of huge proportions, supposing an economic activity that in Spain reached 920 million Euros in the year 2018. This consumption occurs at all levels of sport, from 13% in global numbers, to 100% in some groups of professional sportsmen and women. However, the use of these substances in very few circumstances is done under the advice of a professional, and the athlete takes them on their own. This fact, with the possibility that the product to be taken may contain prohibited substances that do not appear on the labeling, means that an adverse analytical finding can occur in a doping control through so-called ac- cidental doping, which is the use of adulterated or contaminated nutritional supplements containing substances prohibited in sport that have not been declared on the labeling. Key words: Between 11.6% and 25.8% of nutritional supplements contaminated with anabolic androgenic steroids have been found to exist.
    [Show full text]
  • DMAA Ingestion
    Bloomer RJ, et al., J Altern Complement Integr Med 2018, 4: 057 DOI: 10.24966/ACIM-7562/100057 HSOA Journal of Alternative, Complementary & Integrative Medicine Review aid, notwithstanding widespread anecdotal reports of improved exer- 1,3-Dimethylamylamine cise performance and focus following DMAA ingestion. While reports have documented an association between DMAA ingestion and ad- (DMAA): A Brief History verse events, it remains unclear as to the causal role of DMAA, in particular considering the fact that specific to the reported events, and Review of Anecdotal DMAA was often used in combination with other dietary ingredients, prescription medications or recreational drugs. This review discuss- and Laboratory Findings es the history of DMAA, anecdotal and laboratory findings pertaining to its use, and its use today within the dietary supplement market. Richard J Bloomer1*, Nicholas JG Smith1, Damien C Moore1 Keywords: Dietary supplement; Ergogenic aid; Stimulant; Weight and Charles R Yates2 loss 1Center for Nutraceutical and Dietary Supplement Research, School of Health Studies, University of Memphis, Memphis, Tennessee, USA Introduction 2College of Pharmacy, University of Tennessee Health Science Center, While the ingredient referred to as DMAA was once a highly Memphis, Tennessee, USA utilized ingredient in sport nutrition and weight loss dietary supple- ments, it has been the target of much controversy. Also known by the names 2-amino-4-methylhexane, 1,3-dimethylamylamine, 1,3-di- methylpentylamine, methylhexanamine, 4-methyl-2-hexylamine and “Geranamine™” (as well as others), this agent has been largely re- moved from the marketplace due primarily to concerns regarding its overall safety profile. In particular, a variety of case reports describing individuals experiencing adverse events following the use of DMAA alone or within dietary supplements have fueled these concerns.
    [Show full text]
  • Report of the Department of Defense 1,3 Dimethylamylamine (Dmaa) Safety Review Panel
    REPORT OF THE DEPARTMENT OF DEFENSE 1,3 DIMETHYLAMYLAMINE (DMAA) SAFETY REVIEW PANEL 3 JUNE 2013 COL JOHN LAMMIE, EDITOR AND SAFETY PANEL LEAD Index Page 1. Introduction . 3 2. Executive Summary. .6 3. Dimethylamylamine – description of compound. 12 4. Phase I a: Literature Review . 15 5. Phase I b: DoD Reported Adverse Events. 20 6. Phase II a: Interviews of Service Members with Adverse Events. 22 7. Phase II b: Review of FDA Adverse Events . 24 8. Phase III a: Armed Forces Medical Examiners Review. 25 9. Phase III b: Case Control Study . 28 10. Evaluation of evidence . 50 11. Operation Supplement Safety . 54 12. Bibliography . 56 13. Annexes . 67 ANNEX A. DMAA Timeline . 67 ANNEX B. DoD DMAA Safety Panel Members . 71 ANNEX C. Soldier Health and Dietary Supplement Use Questionnaire . 74 ANNEX D. ALFOODACT 034-2011 Army Air Force Exchange Services . .91 ANNEX E. Table of DoD-Reported Adverse Medical Events . 97 ANNEX F. The Naranjo adverse drug reaction (ADR) probability scale . 99 ANNEX G. In-depth Interviews of Service Members with Adverse Events Summary Table . .. .100 2 1. Introduction Since May 2011, four Soldiers who died following physical exercise were found to have traces of dimethylamylamine in their blood analyses. One Soldier died in the Pacific region and was found to have severe coronary disease on autopsy, but the other three were in the Southwestern United States and died of complications from rhabdomyolysis and severe metabolic acidosis. Two of these three Soldiers were reported to have had sickle trait. In a precautionary move in December 2011, the Army and Air Force Exchange System pulled all DMAA containing products off of its Exchange and concession shelves pending the results of a safety review.
    [Show full text]
  • Sports Drug Testing and Toxicology TOP ARTICLES SUPPLEMENT
    Powered by Sports drug testing and toxicology TOP ARTICLES SUPPLEMENT CONTENTS REVIEW: Applications and challenges in using LC–MS/MS assays for quantitative doping analysis Bioanalysis Vol. 8 Issue 12 REVIEW: Current status and recent advantages in derivatization procedures in human doping control Bioanalysis Vol. 7 Issue 19 REVIEW: Advances in the detection of designer steroids in anti-doping Bioanalysis Vol. 6 Issue 6 Review For reprint orders, please contact [email protected] 8 Review 2016/05/28 Applications and challenges in using LC–MS/MS assays for quantitative doping analysis Bioanalysis LC–MS/MS is useful for qualitative and quantitative analysis of ‘doped’ biological Zhanliang Wang‡,1, samples from athletes. LC–MS/MS-based assays at low-mass resolution allow fast Jianghai Lu*,‡,2, and sensitive screening and quantification of targeted analytes that are based on Yinong Zhang1, Ye Tian2, 2 ,2 preselected diagnostic precursor–product ion pairs. Whereas LC coupled with high- Hong Yuan & Youxuan Xu** 1Food & Drug Anti-doping Laboratory, resolution/high-accuracy MS can be used for identification and quantification, both China Anti-Doping Agency, 1st Anding have advantages and challenges for routine analysis. Here, we review the literature Road, ChaoYang District, Beijing 100029, regarding various quantification methods for measuring prohibited substances in PR China athletes as they pertain to World Anti-Doping Agency regulations. 2National Anti-doping Laboratory, China Anti-Doping Agency, 1st Anding Road, First draft submitted:
    [Show full text]
  • ARCI Uniform Classification Guidelines for Foreign Substances, Or Similar State Regulatory Guidelines, Shall Be Assigned Points As Follows
    DRUG TESTING STANDARDS AND PRACTICES PROGRAM. Uniform Classification Guidelines for Foreign Substances And Recommended Penalties Model Rule. January, 2019 (V.14.0) © ASSOCIATION OF RACING COMMISSIONERS INTERNATIONAL – 2019. Association of Racing Commissioners International 2365 Harrodsburg Road- B450 Lexington, Kentucky, USA www.arci.com Page 1 of 66 Preamble to the Uniform Classification Guidelines of Foreign Substances The Preamble to the Uniform Classification Guidelines was approved by the RCI Drug Testing and Quality Assurance Program Committee (now the Drug Testing Standards and Practices Program Committee) on August 26, 1991. Minor revisions to the Preamble were made by the Drug Classification subcommittee (now the Veterinary Pharmacologists Subcommittee) on September 3, 1991. "The Uniform Classification Guidelines printed on the following pages are intended to assist stewards, hearing officers and racing commissioners in evaluating the seriousness of alleged violations of medication and prohibited substance rules in racing jurisdictions. Practicing equine veterinarians, state veterinarians, and equine pharmacologists are available and should be consulted to explain the pharmacological effects of the drugs listed in each class prior to any decisions with respect to penalities to be imposed. The ranking of drugs is based on their pharmacology, their ability to influence the outcome of a race, whether or not they have legitimate therapeutic uses in the racing horse, or other evidence that they may be used improperly. These classes of drugs are intended only as guidelines and should be employed only to assist persons adjudicating facts and opinions in understanding the seriousness of the alleged offenses. The facts of each case are always different and there may be mitigating circumstances which should always be considered.
    [Show full text]
  • TEXAS RACING COMMISSION January 28, 2021 To
    TEXAS RACING COMMISSION P. O. Box 12080, Austin, Texas 78711-2080 8505 Cross Park Drive, Suite 110, Austin, Texas 78754-4552 Phone (512) 833-6699 Fax (512) 833-6907 www.txrc.texas.gov January 28, 2021 To: Stewards, Commission Veterinarians, Test Barn Supervisors, Practicing Veterinarians, Owners, and Trainers From: Chuck Trout, Executive Director Re: Effective February 25, 2021 changes to the following documents: • Permissible Levels of Therapeutic Medications and Naturally Occurring Substances • Equine Medication Classification Policy and Penalty Guidelines • Equine Medication Classification List. This memo is to provide notice that the above listed documents are to be replaced effective this date. The changes include, but are not limited to: • Changes to the list of Permissible Levels of Therapeutic Medications and Naturally Occurring Substances; • Changes to the Equine Medication Classification Policy and Penalty Guidelines; • Changes to the Equine Medication Classification List. These documents are subject to further revision at any time. Test Barn Supervisors - please post this memo and the revised documents in the test barn as soon as possible. Also, please distribute copies of the Permissible Levels of Therapeutic Medications and Naturally Occurring Substances and Equine Medication Classification List to the practicing veterinarians at your racetrack. Licensing Staff - please post this memo and the revised documents where they may be viewed by the public as soon as possible. Copies of these documents will be made available on the Commission's website at http://www.txrc.texas.gov. Attachments: Permissible Levels of Therapeutic Medications and Naturally Occurring Substances Equine Medication Classification Policy and Penalty Guidelines Equine Medication Classification List TEXAS RACING COMMISSION P.
    [Show full text]
  • 3~/3I·-I!.-- -Against- Index No.: Rjino.: DAN HEINS, Doing Business As SHINING STAR ENTERPRISES
    SUPREME COURT OF THE STATE OF NEW YORK COUNTY OF ALBANY PEOPLE OF THE STATE OF NEW YORK, by ERIC T. SCHNEIDERMAN, Attorney General of the State ofNew York, Petitioner, AFFIRMATION 3~/3i·-I!.-- -against- Index No.: RJINo.: DAN HEINS, doing business as SHINING STAR ENTERPRISES, Respondent. DEANJ'JA R. NELSON, an attorney duly admitted to practice law in the State of New York, affirms the following under the penalties of perjury: 1. I am an Assistant Attorney General In Charge in the office of Eric T. Schneiderman, Attorney General of the State of New York (OAG), assigned to the Watertown Regional Office. I am fully familiar with the facts and circumstance of this proceeding, which are based on investigative materials contained in the files of the Attorney General's office. 2. I submit this Affirmation in support of Petitioner's application for an Order and Judgment permanently enjoining Respondent from engaging in deceptive, fraudulent and illegal business practices, requiring that Respondent produce an accounting of mislabeled and misbranded products sold and awarding and penalties and· costs to the State ofNew York 3. Unless otherwise indicated, I make this affirmation upon information and .belief, based upon my investigation, a review of documents and other evidence on file with the Department of Law. Annexed hereto in support of this petition are the fo Howing documents: Ex. I. Affidavit of Senior Investigator Chad Shelmidine, dated 7/6/12, together with Exhibits A-K; Ex. II. Affidavit of Dr. Maja Lundborg-Gray, M.D., FAAEM, FACEP, sworn to on July 5,2012, together with Exhibits A-G; Ex.
    [Show full text]
  • Drug Awareness and Recognition
    Drug Awareness and Recognition R. A. MacKenzie III CEM/CFC/AEMT-P Lewis County Emergency Management Definition of addiction . 1 : the quality or state of being addicted addiction to reading . 2 : compulsive need for and use of a habit- forming substance (such as heroin, nicotine, or alcohol) characterized by tolerance and by well-defined physiological symptoms upon withdrawal; broadly : persistent compulsive use of a substance known by the user to be harmful . Pharmacology . Three main neurotransmitters are affected by these drugs; norepinephrine, dopamine, and serotonin. Increased concentrations of these transmitters in the neuronal synapse occur via increased release from vesticles through direct stimulation, blockade of pre-synaptic uptake and storage , reduced monoamine oxidase activity, and indirect glutamate pathway stimulation. Modification of the chemical structure can result in a dramatically altered pharmacologic profile. Methyl substitutions at the alpha carbon of the phenylethylamine structure result in strong stimulant, cardiovascular, and anorectic properties. WHAT ??? English Please!!!! All of these categories of drugs alter the senses by ether slowing or stimulating concentrations of norepinephrine, dopamine, and serotonin in the neuronal synapse. Effects . Tachycardia . Fast Pulse, Jittery? . Hypertension . High Blood pressure Red Faced? . Agitation . Edgy, mood swings ? . Seizures . Not just typical Colonic Tonic, but focal motor as well . Pupil constriction or dilation . Hallucinations Ketamine . Dissociative anesthetic use in the veterinary practice. Distorts perceptions and produces feelings of detachment from self and environment. Low dose; short attention, and impaired memory . Higher dose; dreamlike states, delirium, and hallucinations. Molly . Diminished fear anxiety insecurity. Stimulation hyperactivity (uncontrollable urge to dance) . Euphoria, arousal, mild psychedela. Currently under study for PTSD, although not approved yet.
    [Show full text]
  • Executive Committee Meeting Minutes, September 21, 2016
    Minutes of the WADA Executive Committee Meeting 21 September 2016, Lausanne, Switzerland The meeting began at 9.00 a.m. 1. Welcome, roll call and observers THE CHAIRMAN welcomed the members to the WADA Executive Committee meeting held in the splendid surroundings of the home of the Association of National Olympic Committees, ANOC, in Lausanne. When he walked around and looked at the offices, he was very envious of the quality of the office accommodation. It was very different to his little office at home. He welcomed two new faces to the table, first of all, Mr Mizuochi of Japan, who had taken over as State Minister for Education, Culture, Sports, Science and Technology (just a small and easy portfolio), and, representing Mr Kaloko from Africa, Mr Machacha Shepande, who had been present the previous day at the think tank. He had to record that he missed and grieved for a great man, the WADA Vice-President, Dr Stofile. His career in life and in sport had been outstanding in every possible way. He had been a great supporter of WADA. When he had left his diplomatic position in Germany, he had gone home and had immediately gone back into service in his country at a university in South Africa. WADA missed Dr Stofile enormously, and he asked that everybody stand for a moment in his memory. THE CHAIRMAN thanked Ms Lindberg, the Secretary General of ANOC, for hosting WADA in the ANOC facilities. MS LINDBERG wished the members a successful meeting. There was full attendance. He had the attendance sheet, which he would pass to his right for the members to sign.
    [Show full text]