Sažeci Abstracts

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Sažeci Abstracts Sažeci Abstracts 20. sim po zij 20th Sympo sium of the Hr vat skog druš tva me di cin skih bio ke mi ča ra Croa tian So cie ty of Me di cal Bioc he mis ts Kro nič na op struk cij ska pluć na Chro nic ob struc ti ve pul mo na ry bo le st – bio ke mij ske zna čaj ke disea se – bioc he mi cal fea tu res Organizatori Organizers H r v a t s k o d r u š t v o m e d i c i n s k i h b i o k e m i č a r a C r o a t i a n S o c i e t y o f M e d i c a l B i o c h e m i s t s Cen tar za pri mi je nje nu me di cin sku bio ke mi ju, Cen tre for Ap plied Me di cal Bioc he mis try, Far ma ceut sko-bio ke mij ski fa kul tet Fa cul ty of Phar ma cy and Bioc he mis try Z a g r e b a č k i V e l e s a j a m Zag reb Fair KON GRES NA DVO RA NA, Z a g r e b a č k i V e l e s a j a m , Z a g r e b , CON GRE SS HA LL, Zag reb Fair, Zag reb, 7. svib nja 2009. May 7, 2009 Sažeci 20. simpozija Hrvatskog društva medicinskih biokemičara, 7. svibanj 2009, Zagreb Abstracts of the 20th Symposium of the Croatian Society of Medical Biochemistry, May 7 2009, Zagreb Sadržaj Contents Sim po zij ska pre da va nja Sympo sium lec tu res Što je KOPB? What is COPD? S a n j a P o p o v i ć - G r l e S a n j a P o p o v i ć - G r l e Ok si da cij ski stres i kro nič na op struk cij ska pluć na O x i d a t i v e s t r e s s a n d c h r o n i c o b s t r u c t i v e p u l m o n a r y bo le st di sea se József Pet rik József Pet rik Dim ci ga re te uz ro ku je ok si da cij ski stres u epi tel nim sta ni- Ci ga ret te smo ke in du ced oxi da ti ve stre ss in ai rway ca ma diš nih pu to va in vit ro i u in vi vo mo de lu kod mi ša epit he lial cel ls in vit ro and a mou se mo del in vi vo An toon J. M. van Oos ter hout An toon J. M. van Oos ter hout Upal ni bi lje zi u kro nič noj op struk cij skoj pluć noj bo les ti In fl a m m a t o r y m a r k e r s i n c h r o n i c o b s t r u c t i v e p u l m o n a r y Ti ha na Žanić Grubišić di sea se Ti ha na Žanić-Grubišić Ge ne ti ka kro nič ne op struk cij ske pluć ne bo les ti Kar me la Barišić G e n e t i c s o f c h r o n i c o b s t r u c t i v e p u l m o n a r y d i s e a s e Kar me la Barišić D a n a š n j e l i j e č e n j e K O P B Cur re nt COPD treat men ts S a n j a P o p o v i ć - G r l e S a n j a P o p o v i ć - G r l e Kronična opstrukcijska plućna bolest i signalne Chro nic ob struc ti ve pul mo na ry di sea se and sig nal li ng molekule mo le cu les L a d a R u m o r a L a d a R u m o r a U l o g a p r o t e a s o m a u d e g r a d a c i j i p r o t e i n a o š t e ć e n i h Ci ga ret te smo ke - in du ced pro tein da ma ge: ro le of the d i m o m c i g a r e t a pro tea so me Ani ta Som bo rac Ani ta Som bo rac Polimorfi zmi stres nih pro tei na i KOPB Heat sho ck pro tei ns po lymor phis ms and COPD Mi re la Matokanović Mi re la Matokanović O r g a n i z a t o r i z a h v a l j u j u t v r t k i G l a x o S m i t h K l i n e d . o . o . z a T h e O r g a n i z e r s w o u l d l i k e t o t h a n k G l a x o S m i t h K l i n e d . o . o . nov ča no pot po ma ga nje Sim po zi ja. for fi nan cial su po rt of the Sympo sium. Biochemia Medica 2009;19(2):A1–A10 A2 Simpozijska predavanja Symposium lectures Što je kro nič na op stuk tiv na pluć na What is chro nic ob struc ti ve pul mo na ry bo le st? di sea se? S a n j a P o p o v i ć - G r l e S a n j a P o p o v i ć - G r l e Kli ni ka za pluć ne bo les ti „Jor da no vac“ Me di cin skog fa kul te ta Sveu či liš ta Uni ver si ty Hos pi tal for lu ng di sea ses „Jor da no vac“, Me di cal School Uni- u Zag re bu, Zag reb ver si ty of Zag reb, Zag reb, Croa tia Kro nič na op stuk tiv na pluć na bo le st (KOPB) je na ziv za bo- C h r o n i c o b s t r u c t i v e p u l m o n a r y d i s e a s e ( C O P D ) i s a t e - les ti ko je smo pri je zva li kro nični bronhi tis i em fi zem. Da- rm for di sea ses pre vious ly na med chro nic bron chi tis and naš nja naj češ će ko riš te na de fi n i c i j a K O P B - a p o t i č e o d i n i - em physe ma. The mo st com mon ly used de fi n i t i o n t o d a y c i j a t i v e S v j e t s k e z d r a v s t v e n e o r g a n i z a c i j e ( W H O ) i A m e - for the COPD is gi ven by the Ini tia ti ve star ted by Wor ld rič kog in sti tu ta za sr ce, plu ća i krv (NHLBI), a ko ja se na zi- Heal th or ga ni za tion (WHO) and Na tio nal Hea rt, Blood va Glo bal Ini tia ti ve for Chro nic Ob struc ti ve Lu ng Di sea ses and Lu ng In sti tu te (NHLBI) - Glo bal Ini tia ti ve for Chro nic (GOLD). De fi n i c i j a K O P B - a g l a s i : “ K r o n i č n a o p s t u k t i v n a O b s t r u c t i v e L u n g D i s e a s e s ( G O L D ) : “ C h r o n i c o b s t r u c t i v e p l u ć n a b o l e s t ( K O P B ) j e b o l e s t k o j a s e m o ž e s p r i j e č i t i i l i - pul mo na ry di sea se (COPD) is pre ven tab le and trea tab- j e č i t i , p o v e z a n a s a z n a č a j n i m i z v a n p l u ć n i m u č i n c i m a , k o - le di sea se wi th so me sig ni fi c a n t e x t r a p u l m o n a r y e ff e ct j e m o g u p r i d o n i j e t i t e ž i n i b o l e s t i u p o j e d i n o g b o l e s n i k a .
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