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The Association of Lower Abdominal Coldness With Integr Med Res (2015) 42–144 100 P2.061 mild in many cases, a complete cure is difficult because of its chronic nature. The aim of this study is to evalu- Indication of Herbal Medicine ate feasibility for massive clinical research and make basic ‘Bojungikgi-tang’: A Systematic Review of analysis of efficacy and safety of acupuncture on functional Randomized Controlled Trials constipation. Methods: We will include patients aged 19 to 65 years Somi Oh 1, Seong-Gyu Ko 1, old satisfying Rome III criteria for functional constipation. 30 Yong-Cheol Shin 1, Bo-Hyoung Jang 1, participants will be recruited, and randomly allocated into Sunju Park 2, Chunhoo Cheon 1, Soobin Jang 1, two groups. The real and sham acupuncture group partic- Ching-Wen Huang 1, Yui Sasaki 1 ipants will receive real and sham acupuncture treatments 1 Kyung Hee University respectively, three times weekly for a total of 12 sessions 2 Daejeon University over four weeks. After 4 weeks’ treatment, acupuncture and sham acupuncture groups were followed up at 2 and 4 Purpose: This study is to conduct systematic review of ran- weeks. The primary outcome is defecation frequencies in a domized controlled trial using herbal medicine ‘Bojungikgi- week, and the secondary outcomes are spontaneous complete tang’ and classify the indication of Bojungikgi-tang by ICD-10. bowel movement, Bristol stool scale, Constipation Assess- Methods: We searched RCTs reporting effect of Bojungikgi- ment Scale, and Adverse events. Safety will be assessed at tang. Literatures were searched from the electronic databases every visit. including PubMed, EMBASE, Cochrane CENTRAL, CNKI, CiNii, Results: This protocol was registered at CRIS registry CINAHL, 5 Korean medical databases and 2 databases special- (KCT0000926). Currently, 20 participants were enrolled in the ized in Korean medicine. There was no limitation of language study and the remaining participants’ recruiting is in progress. and publication year. The risk of bias was evaluated by the Data will be analyzed before (baseline) and after treatment, ‘Risk of Bias’ tool of Cochrane group. Literatures were descrip- and at 2-week/4-week of f/u after the end of treatment accord- tively analyzed. The indications of Bojungikgi-tang in RCT ing to the method described in the protocol. were classified by ICD-10. Conclusion: The results of the trial will provide basis for the Results: From the 1,883 of relevant literatures, 31 efficacy and safety of acupuncture for functional constipation. were included. 2,440 participants were involved in RCT Contact: Joo-Hee Kim, [email protected] using Bojungikgi-tang. The average administration period of Bojungikgi-tang was 56±48.45 days. In clinical trials, http://dx.doi.org/10.1016/j.imr.2015.04.168 Bojungikgi-tang is mainly used as three indications; a tumor- related disease, loss of appetite and fatigue, and immune- P2.063 related diseases. Especially, Bojungikgi-tang is mostly used in cancer related disease (24%). The association of lower abdominal coldness Conclusion: This study classified various indications of with infertility factors by assessing digital Bojungikgi-tang in clinical trials and identified multi target infrared thermal imaging pattern in infertile effect of Bojungikgi-tang. This review would contribute to women provide useful information in the clinical use of Bojungikgi- Jeong-Eun Yoo, Sae-Byul Jang, Eun-Hye Jung tang. Contact: Somi Oh, [email protected] Dunsan Korean Medicine Hospital of Daejeon university http://dx.doi.org/10.1016/j.imr.2015.04.167 Purpose: In Korean traditional medicine, lower abdominal P2.062 coldness is known to induce women infertility both in litera- ture and clinical practice. Digital infrared thermography has Acupuncture for Functional Constipation: an been in use in medical diagnostics, and it is an effective and Ongoing Randomized, Patient-Assessor objective tool for evaluating the subjective sense of coldness. Blinded, Controlled Pilot Clinical Trial The purpose of this study is to investigate the association of Protocol lower abdominal coldness with infertility factors by assessing digital infrared thermal imaging (DITI) pattern to elucidate Joo-Hee Kim, Sung Phil Kim, Jeong Eun Kim, related pathologies. Kyung Min Shin, Hyo-Ju Park, Ae-Ran Kim, Methods: The study involved 38 female patients of age So-Young Jung, Sunmi Choi 20-38 years that had diagnosed of infertility. All the subjects KIOM in this population were screened for upper and lower body using DITI. Based on the image patterns, two different practi- Purpose: Constipation is one of the most common gas- tioners independently classified the subjects into two groups, trointestinal conditions, with prevalence rates reported to lower abdominal coldness and normal. All those showing be 9.2% in South Korea. While constipation is potentially lower abdominal coldness have been analyzed with variables caused by endocrine, metabolic, or neurological disorders of infertility factors, ovulation, uterine, tubal or peritoneal, or several other organic diseases such as intestinal tumor and unknown. Statistical analysis was performed by adopting occlusion or inflammation, most cases are thought to be descriptive and inferential tests. idiopathic. Although the condition can be intermittent or 101 ICCMR 2015 Poster Presentation Abstracts Results: With regard to infertility factors of subjects, Conclusion: These results indicate that acupuncture seventeen had unknown factor, eleven had tubal or perit- induced local microcirculatory changes that were detected by oneal factor, eight had uterine factor, and six had ovulation LDPI, which may represent an index of proper acupuncture factor. Thirty subjects showed thermograms of lower abdom- stimulation. inal coldness in accordance of two practitioners. Subjects Contact: Seorim Min, [email protected] with tubal or peritoneal factor of infertility shown lower abdominal coldness with most high frequency of 90.9% http://dx.doi.org/10.1016/j.imr.2015.04.170 (p=0.237). P2.066 Conclusion: In cross analysis process, correlation of lower abdominal coldness and tubal or peritoneal factor of infertility Food As Medicine Everyday - Research was not statistically significant, however, this would suggest (FAME-R): Evaluating physiological changes clinically significant clue for the treatment. Thermography associated with a shift toward a whole-foods turns out to be a useful tool for identification of lower abdom- diet inal coldness in infertile woman. Further study is supposed to investigate the physiopathological mechanism of lower Kimberly Tippens, Andrew Erlandsen, abdominal coldness in infertile women with large sample size. Robert Graybill Contact: Jeong-Eun Yoo, korea dr [email protected] National College of Natural Medicine http://dx.doi.org/10.1016/j.imr.2015.04.169 Purpose: Prediabetes, or impaired glucose tolerance with- out a formal diagnosis of diabetes, is increasingly prevalent P2.065 in the United States. Without adequate prevention, individ- uals with prediabetes are likely to develop type II diabetes The analgesic effects and local response to within 10 years. Diabetes is inextricably linked with heart microcirculation of acupuncture disease, and a healthful diet is a key behavioral target for Seorim Min 1, Hyangsook Lee 2, Song-Yi Kim 2, these serious public health problems. Numerous public and Ji-Yeun Park 2, Younbyoung Chae 2, private agencies have adopted health promotion and nutrition Hyejung Lee 2, Hi-Joon Park 2 education programs to foster healthy eating behaviors. Indi- viduals at high risk for these behaviorally-mediated chronic 1 Acupuncture and Meridian Science Research diseases may benefit from structured education programs that Center are community-based. The purpose of this study is to assess 2 Korea Institute of Oriental Medicine the impact of a 12-week, community-based nutrition educa- Purpose: Although the local response induced by acupunc- tion course for adults with prediabetes and cardiovascular risk ture manipulation has been considered to be among the factors. important factors that induce the effects of acupuncture, this Methods: A naturopathic physician-led, 12-week nutrition connection has not yet been properly studied with standard- education course has been offered at community-based loca- ized tools. The aims of this study are to examine the local tions in Portland, Oregon, for the past three years. The Food changes in microcirculation that occur at different manipula- as Medicine Everyday (FAME) course curriculum emphasizes tion intensities and explore any associations of these changes whole-grains and a predominately plant-based whole-foods with the analgesic effects of acupuncture. diet. Fifty adults with or at risk for prediabetes will partic- Methods: Twelve healthy volunteers received three ipate in the 12-week nutrition education program. Using a acupuncture interventions, only an insertion, a single manip- pretest-posttest design, we will assess changes in key markers ulation, and repeated manipulations, at the right LI4 (Hegu of diabetes and CVD risk, including hemoglobin A1c, insulin, or Hapgok) in a random order. Skin blood perfusion was lipids, and c-reactive protein. Sustained impact will be eval- measured within a 100 mm2 area ellipse centered on LI4 uated through repeated measurement at three-month and using laser Doppler perfusion imaging (LDPI). Pressure pain nine-month follow-up visits. thresholds were measured at ipsilateral areas, including acu- Results: Data collection began in January 2015. Preliminary points ST25 (abdomen),
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