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Home , Acinus, Apocrine, Duct (anatomy), Epithelium, Exocrine gland, Gland

Lab 4 – Epithelia and IUSM – 2016 I. Introduction Epithelia and Glands II. Learning Objectives III. Keywords IV. Slides A. Epithelia 1. Simple a. Simple squamous b. Simple cuboidal c. Simple columnar d. Pseudostratified columnar 2. Stratified a. Stratified squamous b. Stratified cuboidal c. Stratified columnar d. Transitional B. Exocrine Glands 1. Simple (unbranched ) a. Tubular b. Branched tubular c. Coiled tubular d. Branched acinar 2. Compound (branched ducts) a. Tubular b. Acinar c. Tubulo-acinar SEM of ciliated columnar of the uterine tube V. Summary Lab 4 – Epithelia and Glands IUSM – 2016 I. Introduction Epithelium II. Learning Objectives III. Keywords 1. Greek: epi – “upon”, thele – “teat, ” IV. Slides A. Epithelia 2. Avascular that covers body surfaces, lines body cavities, and forms glands (endocrine and 1. Simple exocrine). a. Simple squamous b. Simple cuboidal 3. Composed of sheets of closely aggregated cells, of c. Simple columnar one or more layers thick, sitting upon a basement d. Pseudostratified columnar membrane. 2. Stratified 4. Creates a barrier between “external” environment a. Stratified squamous and underlying . b. Stratified cuboidal c. Stratified columnar 5. Polarized with a free surface (apical surface), d. Transitional generally facing the external environment or , B. Exocrine Glands and a bound surface (basal surface), facing the 1. Simple (unbranched duct) . a. Tubular 6. Epithelial tissues are categorized by the number of b. Branched tubular -layers and the shape of their cells. c. Coiled tubular d. Branched acinar 7. Exocrine glands are categorized by the arrangement of their duct portion (branched or not) and the 2. Compound (branched ducts) shape of their secretory portions. a. Tubular b. Acinar c. Tubulo-acinar V. Summary Lab 4 – Epithelia and Glands IUSM – 2016 I. Introduction II. Learning Objectives Learning Objectives III. Keywords IV. Slides 1. Understand how epithelia are classified into simple, stratified, and A. Epithelia pseudostratified types and the usual functional significance of each 1. Simple type. a. Simple squamous b. Simple cuboidal 2. Recognize the (extracellular) basement membrane of epithelia, apical c. Simple columnar specializations such as the terminal web, and ultrastructural features d. Pseudostratified columnar of the various types of intercellular junctions. 2. Stratified a. Stratified squamous b. Stratified cuboidal 3. Understand that epithelium forms barriers and compartments by c. Stratified columnar covering and lining the body’s outer and inner surfaces. d. Transitional B. Exocrine Glands 4. Understand that epithelium is specialized for protection (or as a 1. Simple (unbranched duct) barrier), transport, absorption, and . a. Tubular b. Branched tubular 5. Understand that glands are composed mostly of epithelial cell c. Coiled tubular aggregates clustered together to perform specific secretory and/or d. Branched acinar excretory functions and that there are two main types of glands: 2. Compound (branched ducts) exocrine and endocrine. a. Tubular b. Acinar c. Tubulo-acinar V. Summary Lab 4 – Epithelia and Glands IUSM – 2016 I. Introduction II. Learning Objectives Learning Objectives (cont.) III. Keywords IV. Slides A. Epithelia 6. Distinguish the basic differences between the and 1. Simple of a . a. Simple squamous b. Simple cuboidal 7. Understand that exocrine glands can be classified according to four c. Simple columnar features: the secretory portion’s shape (alveolar/acinar vs. tubular), d. Pseudostratified columnar the duct system (simple vs. compound), the nature of the secretion 2. Stratified (serous vs. mucous), and the mode of cell secretion (, a. Stratified squamous , ). b. Stratified cuboidal c. Stratified columnar 8. Continue to appreciate how structure relates to function. d. Transitional B. Exocrine Glands 1. Simple (unbranched duct) a. Tubular b. Branched tubular c. Coiled tubular d. Branched acinar 2. Compound (branched ducts) a. Tubular b. Acinar c. Tubulo-acinar V. Summary Lab 4 – Epithelia and Glands IUSM – 2016 I. Introduction II. Learning Objectives Keywords III. Keywords IV. Slides Acinar Mucous A. Epithelia Apocrine 1. Simple Branched tubular Non-keratinized a. Simple squamous Brush border PCCE b. Simple cuboidal Cilia Pseudostratified columnar c. Simple columnar Coiled tubular Serous d. Pseudostratified columnar Compound gland Simple columnar 2. Stratified Epithelia Simple cuboidal a. Stratified squamous Glands Simple epithelia b. Stratified cuboidal Simple gland Goblet cells Simple squamous c. Stratified columnar Holocrine Stratified cuboidal d. Transitional Intercellular junctions Stratified epithelia B. Exocrine Glands Striated border 1. Simple (unbranched duct) Keratinized Terminal web a. Tubular Merocrine Transitional b. Branched tubular Microvilli Tubular c. Coiled tubular d. Branched acinar 2. Compound (branched ducts) a. Tubular b. Acinar c. Tubulo-acinar V. Summary Lab 4 – Epithelia and Glands IUSM – 2016 I. Introduction Classifying Epithelium II. Learning Objectives III. Keywords 1. The initial classification of epithelial tissue is based upon the number of cell layers between IV. Slides the basement membrane and the apical surface: A. Epithelia a. Simple epithelia are only one cell layer thick; despite how it may appear, all the 1. Simple cells of simple epithelia are directly attached to the basement membrane. a. Simple squamous b. Simple cuboidal b. Stratified epithelia are more than one cell layer thick so that not all the cells are c. Simple columnar directly attached to the basement membrane; the apical layers of cells are attached d. Pseudostratified columnar to the cells below them, not the basement membrane. 2. Stratified 2. Next, epithelia are classified by the shape of the cells composing the tissue: a. Stratified squamous b. Stratified cuboidal a. The shapes may be classified as squamous, cuboidal, or columnar. c. Stratified columnar b. Since it is often difficult to see the actual shape of individual cells, generally the d. Transitional shape of the nucleus is used to determine the shape of the cell. B. Exocrine Glands 1. Simple (unbranched duct) c. For stratified epithelia, the shape of the cells may appear different between the a. Tubular basal layer of the cells and the more apical layers of cells; therefore, the most apical b. Branched tubular cell shape is used to classify the tissue. c. Coiled tubular 3. Finally, specific epithelia are distinguished by the presence of apical modifications such as d. Branched acinar microvilli, cilia, and . 2. Compound (branched ducts) a. Tubular b. Acinar c. Tubulo-acinar V. Summary Lab 4 – Epithelia and Glands IUSM – 2016 I. Introduction Slide 78: , H&E II. Learning Objectives III. Keywords Slide Overview IV. Slides A. Epithelia 1. Simple a. Simple squamous retina b. Simple cuboidal c. Simple columnar optic d. Pseudostratified columnar 2. Stratified a. Stratified squamous b. Stratified cuboidal c. Stratified columnar d. Transitional B. Exocrine Glands look at the interior 1. Simple (unbranched duct) surface of the a. Tubular cornea to see an b. Branched tubular example of simple c. Coiled tubular squamous d. Branched acinar epithelium 2. Compound (branched ducts) a. Tubular b. Acinar c. Tubulo-acinar V. Summary Lab 4 – Epithelia and Glands IUSM – 2016 I. Introduction Slide 78: Eye, H&E II. Learning Objectives III. Keywords IV. Slides A. Epithelia 1. Simple look here for simple a. Simple squamous squamous b. Simple cuboidal epithelium c. Simple columnar d. Pseudostratified columnar thick pink 2. Stratified line is the a. Stratified squamous basement b. Stratified cuboidal example of membrane c. Stratified columnar (nonkeratinized) d. Transitional stratified B. Exocrine Glands squamous 1. Simple (unbranched duct) epithelium a. Tubular b. Branched tubular c. Coiled tubular (air) d. Branched acinar 2. Compound (branched ducts) a. Tubular simple squamous epithelium consists of a single layer of flattened (squamous) cells; specialized types b. Acinar include (lines the interior of vessels and chambers) and (lines the exterior of c. Tubulo-acinar certain organs and body cavities) V. Summary Lab 4 – Epithelia and Glands IUSM – 2016 I. Introduction Slide 45: Autonomic Ganglia, H&E II. Learning Objectives III. Keywords IV. Slides A. Epithelia 1. Simple a. Simple squamous b. Simple cuboidal c. Simple columnar simple d. Pseudostratified columnar squamous 2. Stratified epithelium a. Stratified squamous (endothelium) b. Stratified cuboidal c. Stratified columnar vessel d. Transitional B. Exocrine Glands 1. Simple (unbranched duct) a. Tubular b. Branched tubular c. Coiled tubular d. Branched acinar layers of 2. Compound (branched ducts) smooth muscle a. Tubular b. Acinar c. Tubulo-acinar V. Summary Lab 4 – Epithelia and Glands IUSM – 2016 I. Introduction Slide 14: Kidney, Masson Trichrome II. Learning Objectives III. Keywords Slide Overview IV. Slides A. Epithelia look in the (outer region of an ) to 1. Simple find renal corpuscles with Bowman’s capsule a. Simple squamous lined by simple squamous epithelium b. Simple cuboidal c. Simple columnar d. Pseudostratified columnar 2. Stratified a. Stratified squamous b. Stratified cuboidal cortex (outer) c. Stratified columnar d. Transitional B. Exocrine Glands medulla (inner) 1. Simple (unbranched duct) a. Tubular calyx b. Branched tubular look here for c. Coiled tubular transitional d. Branched acinar epithelium 2. Compound (branched ducts) a. Tubular b. Acinar c. Tubulo-acinar V. Summary Lab 4 – Epithelia and Glands IUSM – 2016 I. Introduction Slide 14: Kidney, Masson Trichrome II. Learning Objectives III. Keywords IV. Slides A. Epithelia using a trichrome stain, blue shows collagen of the 1. Simple basement membrane of a. Simple squamous the simple squamous b. Simple cuboidal epithelium tissue that c. Simple columnar forms the outer layer of d. Pseudostratified columnar Bowman’s capsule 2. Stratified a. Stratified squamous the basement membrane b. Stratified cuboidal is composed of two layers: c. Stratified columnar the d. Transitional (with type IV collagen) B. Exocrine Glands and the reticular lamina (with type III collagen) 1. Simple (unbranched duct) a. Tubular b. Branched tubular c. Coiled tubular d. Branched acinar 2. Compound (branched ducts) a. Tubular b. Acinar the center of the slide shows a glomerulus (capillary network) of a nephron, which compose the parenchyma (functional tissue) of the kidney (~ 1 million nephrons / kidney) c. Tubulo-acinar V. Summary Lab 4 – Epithelia and Glands IUSM – 2016 I. Introduction Slide 14: Kidney, Masson Trichrome II. Learning Objectives III. Keywords IV. Slides A. Epithelia 1. Simple a. Simple squamous simple squamous b. Simple cuboidal epithelium (endothelium) c. Simple columnar lines blood vessels d. Pseudostratified columnar red blood blood vessels, especially venous, 2. Stratified cell can often be distinguished by a. Stratified squamous looking for red blood cells b. Stratified cuboidal nucleus of within the lumen c. Stratified columnar epithelial cell d. Transitional notice that the shape of the B. Exocrine Glands nucleus of the squamous 1. Simple (unbranched duct) epithelial cell is “squashed” a. Tubular (flat and elongated) as is the b. Branched tubular overall shape of the cell c. Coiled tubular d. Branched acinar 2. Compound (branched ducts) a. Tubular b. Acinar c. Tubulo-acinar V. Summary Lab 4 – Epithelia and Glands IUSM – 2016 I. Introduction Slide 14: Kidney, Masson Trichrome II. Learning Objectives III. Keywords simple squamous simple cuboidal IV. Slides epithelium epithelium A. Epithelia 1. Simple a. Simple squamous simple cuboidal epithelium b. Simple cuboidal lines small ducts as seen here c. Simple columnar d. Pseudostratified columnar the nuclei of the cuboidal 2. Stratified epithelial cells are round and a. Stratified squamous generally located in the center of b. Stratified cuboidal the cell c. Stratified columnar d. Transitional this is still a simple epithelium B. Exocrine Glands because all of the cells are directly attached to the basement 1. Simple (unbranched duct) membrane (thin blue line) a. Tubular b. Branched tubular c. Coiled tubular d. Branched acinar 2. Compound (branched ducts) a. Tubular b. Acinar distinguishing the type of epithelium (and apical modifications) will be important later on when discussing the c. Tubulo-acinar kidney in order to distinguish the different tubules (e.g., collecting duct vs. proximal convoluted tubule) V. Summary Lab 4 – Epithelia and Glands IUSM – 2016 I. Introduction Slide 14: Kidney, Masson Trichrome II. Learning Objectives III. Keywords IV. Slides A. Epithelia 1. Simple simple cuboidal a. Simple squamous epithelium b. Simple cuboidal (duct in cross section) c. Simple columnar d. Pseudostratified columnar 2. Stratified a. Stratified squamous b. Stratified cuboidal c. Stratified columnar d. Transitional B. Exocrine Glands 1. Simple (unbranched duct) a. Tubular b. Branched tubular c. Coiled tubular simple cuboidal epithelium d. Branched acinar (duct in longitudinal section) 2. Compound (branched ducts) a. Tubular b. Acinar c. Tubulo-acinar V. Summary Lab 4 – Epithelia and Glands IUSM – 2016 I. Introduction Slide 105: , H&E II. Learning Objectives III. Keywords IV. Slides A. Epithelia 1. Simple a. Simple squamous b. Simple cuboidal look at the tissue c. Simple columnar surrounding the d. Pseudostratified columnar lumen to find 2. Stratified simple columnar a. Stratified squamous epithelium b. Stratified cuboidal lumen c. Stratified columnar d. Transitional B. Exocrine Glands 1. Simple (unbranched duct) a. Tubular b. Branched tubular c. Coiled tubular d. Branched acinar 2. Compound (branched ducts) a. Tubular b. Acinar c. Tubulo-acinar V. Summary Lab 4 – Epithelia and Glands IUSM – 2016 I. Introduction Slide 105: Gallbladder, H&E II. Learning Objectives III. Keywords IV. Slides A. Epithelia 1. Simple the gallbladder has very tall a. Simple squamous simple b. Simple cuboidal columnar c. Simple columnar epithelium lumen d. Pseudostratified columnar 2. Stratified notice the a. Stratified squamous column-shaped b. Stratified cuboidal nuclei located c. Stratified columnar toward the basal d. Transitional aspect of the cells B. Exocrine Glands 1. Simple (unbranched duct) basement a. Tubular membrane b. Branched tubular underlying c. Coiled tubular connective tissue d. Branched acinar 2. Compound (branched ducts) a. Tubular a mucosa (or ), as seen here, is a layer of an organ b. Acinar composed of an epithelium and the underlying c. Tubulo-acinar V. Summary Lab 4 – Epithelia and Glands IUSM – 2016 I. Introduction Slide 4: Duodenum, BF PAS II. Learning Objectives III. Keywords IV. Slides A. Epithelia 1. Simple a. Simple squamous a is a b. Simple cuboidal specialized type of c. Simple columnar epithelial gland cell; d. Pseudostratified columnar simple why does it stain 2. Stratified columnar purple with PAS a. Stratified squamous epithelium stain? b. Stratified cuboidal c. Stratified columnar d. Transitional B. Exocrine Glands 1. Simple (unbranched duct) a. Tubular b. Branched tubular c. Coiled tubular d. Branched acinar 2. Compound (branched ducts) the purple/pink border is glycocalyx (glycolipids/glycoproteins) coating the microvilli on the apical a. Tubular surface of the epithelium, giving a brush or striated border appearance; notice that in light microscopy b. Acinar individual microvilli cannot be seen – they are only seen as a collective border – while individual cilia or c. Tubulo-acinar stereocilia can be seen (none are seen here but will be seen later) V. Summary Lab 4 – Epithelia and Glands IUSM – 2016 Slide 21: , Masson Trichrome I. Introduction II. Learning Objectives III. Keywords IV. Slides A. Epithelia 1. Simple a. Simple squamous b. Simple cuboidal c. Simple columnar d. Pseudostratified columnar simple 2. Stratified columnar a. Stratified squamous epithelium b. Stratified cuboidal c. Stratified columnar striated border of d. Transitional microvilli B. Exocrine Glands 1. Simple (unbranched duct) a. Tubular b. Branched tubular c. Coiled tubular d. Branched acinar 2. Compound (branched ducts) a. Tubular the terminal web (seen as a thin dark line) is composed of filaments running perpendicular b. Acinar and below the microvilli; it serves to connect and anchor the actin filaments of the with c. Tubulo-acinar those extending into the microvilli V. Summary Lab 4 – Epithelia and Glands IUSM – 2016 Slide 19: Oviduct, Masson Trichrome I. Introduction II. Learning Objectives III. Keywords IV. Slides A. Epithelia 1. Simple a. Simple squamous b. Simple cuboidal cilia c. Simple columnar on the apical d. Pseudostratified columnar surface of the simple columnar 2. Stratified epithelium a. Stratified squamous b. Stratified cuboidal the folds of the tissue c. Stratified columnar can make it difficult to d. Transitional tell if the epithelium is B. Exocrine Glands simple or stratified; 1. Simple (unbranched duct) always look at the least a. Tubular folded (thinnest) area b. Branched tubular when categorizing the c. Coiled tubular tissue type d. Branched acinar 2. Compound (branched ducts) cilia vs. microvilli: cilia are larger, cytoplasmic processes containing , while microvilli are a. Tubular short, cytoplasmic projections containing actin filaments; while it may be possible to distinguish individual b. Acinar cilia in light microscopy, this is not possible with microvilli c. Tubulo-acinar V. Summary Lab 4 – Epithelia and Glands IUSM – 2016 I. Introduction Slide 2: and , Trichrome II. Learning Objectives III. Keywords Slide Overview IV. Slides A. Epithelia 1. Simple the thyroid gland is found a. Simple squamous adjacent to the trachea; it b. Simple cuboidal is easily identified by the c. Simple columnar presence of numerous d. Pseudostratified columnar colloid-filled follicles 2. Stratified (at arrow tip) a. Stratified squamous b. Stratified cuboidal tracheal rings of c. Stratified columnar hyaline cartilage lumen d. Transitional B. Exocrine Glands 1. Simple (unbranched duct) lumen of the trachea is a. Tubular lined by pseudostratified b. Branched tubular ciliated columnar c. Coiled tubular epithelium (PCCE), d. Branched acinar sometimes referred to simply as 2. Compound (branched ducts) a. Tubular b. Acinar c. Tubulo-acinar V. Summary Lab 4 – Epithelia and Glands IUSM – 2016 I. Introduction Slide 140: Trachea, H&E II. Learning Objectives III. Keywords IV. Slides A. Epithelia 1. Simple a. Simple squamous b. Simple cuboidal c. Simple columnar d. Pseudostratified columnar 2. Stratified look at the tissue a. Stratified squamous surrounding the lumen to find b. Stratified cuboidal pseudostratified lumen ciliated columnar c. Stratified columnar epithelium (PCCE) d. Transitional B. Exocrine Glands 1. Simple (unbranched duct) a. Tubular b. Branched tubular c. Coiled tubular d. Branched acinar 2. Compound (branched ducts) a. Tubular how does this slide look different from the slide of the gallbladder (slide 105) seen earlier? b. Acinar what differences can be used to distinguish the slide of the gallbladder vs. the trachea? c. Tubulo-acinar V. Summary Lab 4 – Epithelia and Glands IUSM – 2016 Slide 140: Trachea, H&E I. Introduction II. Learning Objectives III. Keywords IV. Slides are the small A. Epithelia cilia hair-like projections 1. Simple into the lumen off the a. Simple squamous lumen apical surface of the b. Simple cuboidal epithelium c. Simple columnar d. Pseudostratified columnar 2. Stratified a. Stratified squamous b. Stratified cuboidal c. Stratified columnar pseudostratified d. Transitional ciliated columnar B. Exocrine Glands epithelium (PCCE) 1. Simple (unbranched duct) also known as a. Tubular respiratory epithelium b. Branched tubular c. Coiled tubular d. Branched acinar 2. Compound (branched ducts) even though the PCCE appears to be stratified, it is a simple epithelium because all the cells are directly a. Tubular attached to the basement membrane (thin pink line); also note that the red blood cells seen in the tracheal b. Acinar lumen are an artifact – they are the result of the slide preparation when they leaked out of the blood c. Tubulo-acinar vessels seen in the tissue below V. Summary Lab 4 – Epithelia and Glands IUSM – 2016 Slide 39: , H&E I. Introduction II. Learning Objectives III. Keywords IV. Slides A. Epithelia stored 1. Simple sperm cells a. Simple squamous b. Simple cuboidal stereocilia c. Simple columnar on the apical surface of the d. Pseudostratified columnar pseudostratified columnar 2. Stratified epithelium a. Stratified squamous (not PCCE because not ciliated) b. Stratified cuboidal c. Stratified columnar in general, the d. Transitional reproductive tract and B. Exocrine Glands special organs are 1. Simple (unbranched duct) good places in to a. Tubular find unique structures and b. Branched tubular “exceptions” to the rules c. Coiled tubular d. Branched acinar 2. Compound (branched ducts) stereocilia vs. cilia: stereocilia are not actually cilia but a rare, unusually long, immotile type of microvilli a. Tubular (contain actin filaments) found only in the male reproductive tract (epididymis and ductus deferens) and the b. Acinar hair cells of the inner c. Tubulo-acinar V. Summary Lab 4 – Epithelia and Glands IUSM – 2016 I. Introduction Slide 120: Eye, H&E II. Learning Objectives III. Keywords IV. Slides A. Epithelia 1. Simple a. Simple squamous b. Simple cuboidal c. Simple columnar d. Pseudostratified columnar 2. Stratified simple a. Stratified squamous squamous b. Stratified cuboidal non-keratinized stratified squamous epithelium c. Stratified columnar epithelium d. Transitional on the anterior (exterior) B. Exocrine Glands surface of the cornea 1. Simple (unbranched duct) a. Tubular b. Branched tubular c. Coiled tubular d. Branched acinar 2. Compound (branched ducts) a. Tubular b. Acinar c. Tubulo-acinar V. Summary Lab 4 – Epithelia and Glands IUSM – 2016 I. Introduction Slide 78: Eye, H&E II. Learning Objectives III. Keywords IV. Slides A. Epithelia 1. Simple a. Simple squamous b. Simple cuboidal c. Simple columnar d. Pseudostratified columnar 2. Stratified a. Stratified squamous nuclei b. Stratified cuboidal c. Stratified columnar d. Transitional B. Exocrine Glands 1. Simple (unbranched duct) non-keratinized a. Tubular stratified squamous b. Branched tubular epithelium c. Coiled tubular d. Branched acinar clearly this epithelium is stratified, but should it be classified as stratified cuboidal or stratified squamous? 2. Compound (branched ducts) a. Tubular the convention is to classify epithelium based upon the appearance of the apical layers of cells, not the b. Acinar basal – so while the basal cells of this epithelium are cuboidal in shape, it is classified as squamous c. Tubulo-acinar because of the very flat (“squashed”) apical layers; also note that true stratified cuboidal epithelium is very rarely ever more than two layers thick and this epithelium is at least four cell layers thick V. Summary Lab 4 – Epithelia and Glands IUSM – 2016 I. Introduction Slide 43: , H&E II. Learning Objectives III. Keywords IV. Slides A. Epithelia 1. Simple lumen a. Simple squamous b. Simple cuboidal c. Simple columnar d. Pseudostratified columnar 2. Stratified a. Stratified squamous b. Stratified cuboidal non-keratinized c. Stratified columnar stratified squamous d. B. Exocrine Glands 1. Simple (unbranched duct) a. Tubular b. Branched tubular loose connective c. Coiled tubular tissue d. Branched acinar 2. Compound (branched ducts) a. Tubular notice that nuclei can be seen in all the strata of the epithelium from the basement membrane all the way b. Acinar to the apical surface at the lumen; as nuclei are still present in the apical cells, they cannot be keratinized, therefore this is a non-keratinized stratified squamous epithelium c. Tubulo-acinar V. Summary Lab 4 – Epithelia and Glands IUSM – 2016 I. Introduction Slide 7: Larynx, Trichrome II. Learning Objectives III. Keywords IV. Slides Slide 133: Uterine , H&E A. Epithelia 1. Simple a. Simple squamous b. Simple cuboidal c. Simple columnar d. Pseudostratified columnar 2. Stratified a. Stratified squamous b. Stratified cuboidal c. Stratified columnar d. Transitional B. Exocrine Glands 1. Simple (unbranched duct) a. Tubular look within the larynx to find b. Branched tubular the /folds which are c. Coiled tubular composed of non-keratinized look at the cervix (opening to ) d. Branched acinar stratified squamous and vaginal wall to see additional 2. Compound (branched ducts) epithelium examples of non-keratinized a. Tubular stratified squamous epithelium b. Acinar c. Tubulo-acinar V. Summary Lab 4 – Epithelia and Glands IUSM – 2016 I. Introduction Slide 36: Thin , H&E II. Learning Objectives III. Keywords IV. Slides keratin A. Epithelia the separation of the layers 1. Simple is an artifact of the slide a. Simple squamous preparation b. Simple cuboidal c. Simple columnar d. Pseudostratified columnar 2. Stratified the of the a. Stratified squamous skin is composed of b. Stratified cuboidal keratinized c. Stratified columnar stratified squamous d. Transitional epithelium B. Exocrine Glands 1. Simple (unbranched duct) a. Tubular b. Branched tubular c. Coiled tubular d. Branched acinar 2. Compound (branched ducts) a. Tubular notice that nuclei cannot be seen in the apical layers of the tissue; the organelles of these cells have been b. Acinar replaced by large amounts of keratin proteins, thus this is a keratinized stratified squamous epithelium c. Tubulo-acinar V. Summary Lab 4 – Epithelia and Glands IUSM – 2016 I. Introduction II. Learning Objectives Slide 11: , PAS & AB III. Keywords IV. Slides A. Epithelia stratified cuboidal 1. Simple epithelium a. Simple squamous b. Simple cuboidal stratified epithelium c. Simple columnar are named after the d. Pseudostratified columnar shape of the most 2. Stratified apical cell layer, so a. Stratified squamous these are stratified b. Stratified cuboidal cuboidal even though c. Stratified columnar the more basal cells d. Transitional may appear squamous B. Exocrine Glands 1. Simple (unbranched duct) a. Tubular b. Branched tubular c. Coiled tubular d. Branched acinar 2. Compound (branched ducts) a. Tubular stratified cuboidal epithelia are generally only found in the ducts of sweat glands and in large ducts of exocrine glands, such as the submandibular seen here; stratified cuboidal (and stratified b. Acinar columnar, which is even more rare) are usually never more than two cell layers thick and usually lack any c. Tubulo-acinar apical modifications V. Summary Lab 4 – Epithelia and Glands IUSM – 2016 Slide 138: Eyelid, H&E I. Introduction II. Learning Objectives III. Keywords IV. Slides A. Epithelia 1. Simple a. Simple squamous b. Simple cuboidal tarsus c. Simple columnar (tarsal plate) d. Pseudostratified columnar dense CT that contributes form 2. Stratified and support to eyelid; contains a. Stratified squamous glands that produce oils to form b. Stratified cuboidal a surface layer on tear film, reducing evaporation, and c. Stratified columnar lubricating ocular surface d. Transitional B. Exocrine Glands 1. Simple (unbranched duct) conjunctiva a. Tubular stratified columnar b. Branched tubular epithelium w/ goblet cells c. Coiled tubular d. Branched acinar 2. Compound (branched ducts) stratified columnar epithelia are very rare and generally only found in very large ducts of exocrine glands or a. Tubular within the reproductive tract; additionally, it can be found composing the conjunctiva which is a mucous b. Acinar membrane that lines that inside of the eyelid and the anterior portion of the sclera (white part) of the eye; c. Tubulo-acinar because stratified columnar epithelium is so rare, if trying to identify an epithelium, it is much more likely to be pseudostratified columnar than true stratified columnar (especially if apical modifications are present) V. Summary Lab 4 – Epithelia and Glands IUSM – 2016 Slide 16: Aorta, Vena Cava, I. Introduction Slide Overview II. Learning Objectives III. Keywords IV. Slides A. Epithelia 1. Simple a. Simple squamous b. Simple cuboidal c. Simple columnar d. Pseudostratified columnar 2. Stratified a. Stratified squamous b. Stratified cuboidal c. Stratified columnar d. Transitional look here for the ureter, which B. Exocrine Glands carries from the kidney 1. Simple (unbranched duct) to the a. Tubular b. Branched tubular c. Coiled tubular d. Branched acinar transitional epithelium lines the lumen of all urinary organs, so 2. Compound (branched ducts) it is sometimes referred to simply as a. Tubular urinary epithelium b. Acinar c. Tubulo-acinar V. Summary Lab 4 – Epithelia and Glands IUSM – 2016 I. Introduction Slide 16: Aorta, Vena Cava, Ureter II. Learning Objectives III. Keywords IV. Slides A. Epithelia lumen 1. Simple multinucleated a. Simple squamous cell b. Simple cuboidal c. Simple columnar “bulging” d. Pseudostratified columnar appearance of 2. Stratified apical surface a. Stratified squamous b. Stratified cuboidal c. Stratified columnar d. Transitional B. Exocrine Glands 1. Simple (unbranched duct) a. Tubular transitional b. Branched tubular epithelium c. Coiled tubular d. Branched acinar 2. Compound (branched ducts) transitional epithelium (or urinary epithelium) is found only within the organs of the , and its a. Tubular appearance changes as it stretches and flattens out; the apical cells are sometimes referred to as umbrella cells and may be multinucleated, and when not stretched, have a characteristic “bulging” or “pear-shaped” protrusion b. Acinar into the lumen; individual strata are difficult to clearly define, but there are generally 6-8 cell layers (much more c. Tubulo-acinar than seen in stratified cuboidal or columnar) V. Summary Lab 4 – Epithelia and Glands IUSM – 2016 I. Introduction II. Learning Objectives III. Keywords Slide 118: Bladder, H&E Slide 70 (464): Bladder, H&E IV. Slides A. Epithelia 1. Simple a. Simple squamous b. Simple cuboidal c. Simple columnar d. Pseudostratified columnar 2. Stratified a. Stratified squamous b. Stratified cuboidal c. Stratified columnar d. Transitional lumen lumen B. Exocrine Glands non-distended (empty) bladder distended (full) bladder 1. Simple (unbranched duct) a. Tubular transitional b. Branched tubular epithelium c. Coiled tubular d. Branched acinar 2. Compound (branched ducts) notice the change in the appearance of the epithelium as the bladder goes from being empty to being a. Tubular full; why is the ability of this epithelium to stretch and rebound so important? b. Acinar c. Tubulo-acinar V. Summary Lab 4 – Epithelia and Glands IUSM – 2016 I. Introduction Classifying Exocrine Glands II. Learning Objectives III. Keywords 1. There are three principal ways of classifying exocrine glands: (1) based upon the IV. Slides nature of their secretory product (e.g., mucous and serous); (2) based upon their A. Epithelia mode of secretion (e.g., merocrine, apocrine, and holocrine); or (3) based upon 1. Simple their morphology. a. Simple squamous b. Simple cuboidal 2. When categorizing glands based upon morphology, glands are described both by c. Simple columnar the shapes of their duct portions (parts of the gland which are non-secretory) and d. Pseudostratified columnar their secretory portions: 2. Stratified a. Ducts, which are non-secretory epithelial cells that conduct the secretory a. Stratified squamous product onto the epithelial surface, may be unbranched ( ) or b. Stratified cuboidal simple branched ( ). c. Stratified columnar compound d. Transitional b. Secretory portions, which are the epithelial cells responsible for the B. Exocrine Glands production of the glandular product (e.g., , digestive enzymes, etc.), 1. Simple (unbranched duct) can be arranged in either tubular or rounded (acinar) configurations. a. Tubular b. Branched tubular c. Additionally, the secretory portions can be themselves be branched or c. Coiled tubular coiled in shape. d. Branched acinar 2. Compound (branched ducts) 3. Several configurations of glands are rarely seen; for instance, simple, acinar a. Tubular glands are seen during development of urethral glands but are otherwise generally b. Acinar not seen. c. Tubulo-acinar V. Summary Lab 4 – Epithelia and Glands IUSM – 2016 I. Introduction II. Learning Objectives III. Keywords IV. Slides A. Epithelia 1. Simple a. Simple squamous b. Simple cuboidal c. Simple columnar d. Pseudostratified columnar 2. Stratified a. Stratified squamous b. Stratified cuboidal c. Stratified columnar d. Transitional B. Exocrine Glands 1. Simple (unbranched duct) a. Tubular b. Branched tubular c. Coiled tubular d. Branched acinar 2. Compound (branched ducts) Junqueira, 13th ed. a. Tubular b. Acinar c. Tubulo-acinar V. Summary Lab 4 – Epithelia and Glands IUSM – 2016 I. Introduction Slide 26: Ileum, PAS Slide 27: Ileum, H&E II. Learning Objectives III. Keywords IV. Slides A. Epithelia 1. Simple a. Simple squamous b. Simple cuboidal c. Simple columnar d. Pseudostratified columnar 2. Stratified a. Stratified squamous b. Stratified cuboidal c. Stratified columnar d. Transitional B. Exocrine Glands 1. Simple (unbranched duct) goblet cells are the simplest type of ; they are unicellular glands consisting of only a single, a. Tubular specialized epithelial cell (epithelial cells are the major component of all the glands of the body) and are found interspersed amongst other epithelial cells, such as the simple columnar cells seen above in the ileum; b. Branched tubular they secrete (glycosylated proteins), the main components of c. Coiled tubular d. Branched acinar the apical portion of the cell fills with the secretory product, displacing the cytoplasmic organelles to the 2. Compound (branched ducts) basal region of the cell, giving the cell the general appearance of a goblet/chalice a. Tubular b. Acinar what accounts for the difference in staining between the goblet cells seen above in PAS staining and in H&E? c. Tubulo-acinar V. Summary Lab 4 – Epithelia and Glands IUSM – 2016 I. Introduction Slide 27: Ileum, H&E II. Learning Objectives III. Keywords IV. Slides A. Epithelia 1. Simple a. Simple squamous b. Simple cuboidal c. Simple columnar d. Pseudostratified columnar 2. Stratified secretory cells a. Stratified squamous form the wall b. Stratified cuboidal of the gland c. Stratified columnar d. Transitional B. Exocrine Glands lumen 1. Simple (unbranched duct) a. Tubular simple b. Branched tubular tubular c. Coiled tubular glands d. Branched acinar 2. Compound (branched ducts) the secretory cells of simple, tubular glands discharge their product into the straight, tubular lumen which a. Tubular they line; the lumen then empties via a short duct portion onto the apical surface of the epithelium (the b. Acinar lumen of the ileum); the glands are seen in longitudinal section but may also be seen in cross-section c. Tubulo-acinar V. Summary Lab 4 – Epithelia and Glands IUSM – 2016 I. Introduction Slide 6: Colon, PAS & Azure Blue II. Learning Objectives III. Keywords IV. Slides A. Epithelia 1. Simple a. Simple squamous b. Simple cuboidal c. Simple columnar d. Pseudostratified columnar 2. Stratified a. Stratified squamous simple b. Stratified cuboidal tubular c. Stratified columnar gland d. Transitional B. Exocrine Glands 1. Simple (unbranched duct) a. Tubular b. Branched tubular c. Coiled tubular d. Branched acinar 2. Compound (branched ducts) a. Tubular b. Acinar due to sectioning, it is common to not be able to see the entire gland extending to c. Tubulo-acinar the apical surface (lumen) V. Summary Lab 4 – Epithelia and Glands IUSM – 2016 I. Introduction Slide 42 (464): Pyloric , H&E II. Learning Objectives III. Keywords IV. Slides A. Epithelia 1. Simple a. Simple squamous are the duct b. Simple cuboidal portions of the glands, c. Simple columnar emptying into the lumen of d. Pseudostratified columnar the stomach 2. Stratified a. Stratified squamous b. Stratified cuboidal c. Stratified columnar pyloric (gastric) glands are d. Transitional lined almost entirely by B. Exocrine Glands mucus-secreting cells and 1. Simple (unbranched duct) are generally classified as a. Tubular branched tubular b. Branched tubular c. Coiled tubular d. Branched acinar 2. Compound (branched ducts) a. Tubular simple, branched tubular glands are found almost exclusively in the stomach; several tubular secretory b. Acinar portions drain together into a single, unbranched duct which then empties onto the surface of the gland c. Tubulo-acinar (the stomach lumen) V. Summary Lab 4 – Epithelia and Glands IUSM – 2016 I. Introduction Slide 36: Thin Skin, H&E II. Learning Objectives III. Keywords IV. Slides A. Epithelia 1. Simple a. Simple squamous b. Simple cuboidal unbranched duct portion c. Simple columnar of simple coiled tubular d. Pseudostratified columnar 2. Stratified a. Stratified squamous b. Stratified cuboidal c. Stratified columnar d. Transitional B. Exocrine Glands coiled tubular 1. Simple (unbranched duct) secretory portion a. Tubular b. Branched tubular c. Coiled tubular d. Branched acinar 2. Compound (branched ducts) sweat glands are almost the only example of simple, coiled tubular glands; their secretory portions are a. Tubular highly-coiled simple cuboidal epithelium which drain into the unbranched, non-secretory duct portion b. Acinar (darker staining) which is lined by stratified cuboidal epithelium and empties onto the surface of the skin c. Tubulo-acinar V. Summary Lab 4 – Epithelia and Glands IUSM – 2016 I. Introduction Slide 51: Thin Skin, H&E II. Learning Objectives III. Keywords IV. Slides A. Epithelia 1. Simple a. Simple squamous b. Simple cuboidal c. Simple columnar d. Pseudostratified columnar 2. Stratified a. Stratified squamous hair follicle b. Stratified cuboidal c. Stratified columnar d. Transitional B. Exocrine Glands 1. Simple (unbranched duct) sebaceous glands are a. Tubular simple branched b. Branched tubular acinar glands c. Coiled tubular d. Branched acinar 2. Compound (branched ducts) sebaceous glands are simple, branched acinar glands consisting of several secretory acini surrounding a a. Tubular hair follicle, which serves as the single, unbranched duct; the acini empty their product (sebum) into their b. Acinar excretory duct (the hair follicle) via holocrine secretion c. Tubulo-acinar V. Summary Lab 4 – Epithelia and Glands IUSM – 2016 I. Introduction Slide 43 (464): Duodenum, H&E II. Learning Objectives III. Keywords IV. Slides A. Epithelia 1. Simple a. Simple squamous branched duct b. Simple cuboidal portions c. Simple columnar d. Pseudostratified columnar 2. Stratified a. Stratified squamous b. Stratified cuboidal c. Stratified columnar coiled and branched d. Transitional tubular secretory portions B. Exocrine Glands 1. Simple (unbranched duct) a. Tubular b. Branched tubular c. Coiled tubular d. Branched acinar 2. Compound (branched ducts) Brunner’s glands of the duodenum (the first segment of the small intestine) are compound, tubular glands a. Tubular (more specifically, they are compound, branched coiled tubular glands); there are extensive secretory b. Acinar portions that secrete a mucus-rich alkaline product to neutralize the acidic contents emptying into the c. Tubulo-acinar duodenum from the stomach V. Summary Lab 4 – Epithelia and Glands IUSM – 2016 I. Introduction Slide 154: , H&E II. Learning Objectives III. Keywords IV. Slides A. Epithelia 1. Simple pancreatic a. Simple squamous island b. Simple cuboidal (endocrine) c. Simple columnar d. Pseudostratified columnar 2. Stratified a. Stratified squamous secretory acini b. Stratified cuboidal compose the majority c. Stratified columnar of the parenchyma of d. Transitional the pancreas B. Exocrine Glands 1. Simple (unbranched duct) a. Tubular exocrine duct b. Branched tubular c. Coiled tubular d. Branched acinar 2. Compound (branched ducts) the exocrine portion of the pancreas is a compound, acinar gland composed of secretory epithelial cells arranged in an acinar (Lt. “grape”) configuration; at the center of the acini are small ducts which are not a. Tubular usually able to be seen; these small ducts drain into larger ducts, lined by simple cuboidal epithelium, which b. Acinar form the branched duct system; eventually all the ducts converge into the main which c. Tubulo-acinar empties into the duodenum V. Summary Lab 4 – Epithelia and Glands IUSM – 2016 I. Introduction Slide 154: Pancreas, H&E II. Learning Objectives III. Keywords IV. Slides A. Epithelia light-staining group of 1. Simple cells are an endocrine a. Simple squamous pancreatic islet b. Simple cuboidal c. Simple columnar d. Pseudostratified columnar 2. Stratified acini a. Stratified squamous (serous) b. Stratified cuboidal serous secretory c. Stratified columnar acini comprise the d. Transitional majority of B. Exocrine Glands parenchyma of 1. Simple (unbranched duct) pancreas a. Tubular b. Branched tubular c. Coiled tubular d. Branched acinar 2. Compound (branched ducts) a. Tubular the serous acini (plural of ) have 5-10 secretory cells surrounding a small central duct (lumen is not b. Acinar readily visible); the apical ends are eosinophilic due to the presences of secretory granules, while the basal c. Tubulo-acinar ends are basophilic due to the nucleus and rER V. Summary Lab 4 – Epithelia and Glands IUSM – 2016 I. Introduction Slide 72: Submandibular Gland, H&P II. Learning Objectives III. Keywords IV. Slides mucous cells A. Epithelia secrete - rich products 1. Simple a. Simple squamous mucous = adj. b. Simple cuboidal mucus = noun c. Simple columnar d. Pseudostratified columnar serous cells secrete protein- 2. Stratified rich products a. Stratified squamous b. Stratified cuboidal : c. Stratified columnar “half moon” d. Transitional shape of serous light-staining B. Exocrine Glands portion of gland exocrine ducts of 1. Simple (unbranched duct) surrounding simple cuboidal mucous portion a. Tubular epithelium and b. Branched tubular central lumen c. Coiled tubular d. Branched acinar the submandibular gland is an example of a compound, tubulo-acinar gland; it is composed of secretory units 2. Compound (branched ducts) arranged as branched tubular, branched acinar, and combined tubular units capped by acinar ends; there are a. Tubular both serous (eosinophilic-staining) and mucous (pale-staining) secretory cells; the mucous cells tend to form b. Acinar the tubular components and the serous cells form the acinar components; all the secretory portions converge c. Tubulo-acinar into branched ducts which converge and empty into the oral cavity V. Summary Lab 4 – Epithelia and Glands IUSM – 2016 Common Confusion: I. Introduction Pseudostratified vs. Stratified Cuboidal/Columnar Epithelium II. Learning Objectives III. Keywords IV. Slides Pseudostratified: simple epithelium with all cells A. Epithelia attached to basement membrane; found in upper 1. Simple Ci and reproductive system (rare)

a. Simple squamous Gb Look for: (1) nuclei give appearance of multiple b. Simple cuboidal layers (more than two) but are not in-line forming c. Simple columnar strata; (2) nuclei are generally confined to basal 2/3 of epithelium; (3) cilia ( ) are usually present d. Pseudostratified columnar Ci (PCCE), while never present on true stratified 2. Stratified epithelia; (4) goblet cells (Gb) are often interspersed a. Stratified squamous b. Stratified cuboidal Ductus Deferens Trachea c. Stratified columnar d. Transitional Stratified cuboidal/columnar: stratified cuboidal and columnar epithelia are rare and mainly B. Exocrine Glands restricted to large ducts and parts of the 1. Simple (unbranched duct) reproductive system; sectioning may skew a. Tubular appearance, so look at thinnest portion of b. Branched tubular epithelium to visualize true organization c. Coiled tubular Look for: (1) generally no more than two cell layers d. Branched acinar thick; (2) clearly defined strata; (3) apical nuclei are 2. Compound (branched ducts) in-line and have characteristic shape; (4) lack apical modifications a. Tubular b. Acinar Stratified cuboidal Stratified cuboidal c. Tubulo-acinar V. Summary Lab 4 – Epithelia and Glands IUSM – 2016 Common Confusion: I. Introduction Pseudostratified vs. Transitional Epithelium II. Learning Objectives III. Keywords Pseudostratified: simple epithelium with all cells IV. Slides attached to basement membrane; found in upper A. Epithelia respiratory tract and reproductive system (rare) 1. Simple Look for: (1) all cells are directly attached to a. Simple squamous basement membrane so nuclei normally do not b. Simple cuboidal appear directly stacked above one another; (2) c. Simple columnar nuclei are generally confined to basal 2/3 of epithelium; (3) more apical nuclei have columnar d. Pseudostratified columnar appearance instead of rounded; (4) cilia are usually 2. Stratified present (PCCE); (5) goblet cells are often a. Stratified squamous interspersed Ductus Deferens Trachea b. Stratified cuboidal c. Stratified columnar Transitional: stratified epithelium found only within organs of the urinary system d. Transitional B. Exocrine Glands Look for: (1) multiple layers of nuclei generally with 1. Simple (unbranched duct) rounded appearance (but more layers and less in- a. Tubular line nuclei than stratified cuboidal epithelium); (2) multinucleated cell may be present at apical surface; b. Branched tubular (3) when tissue is relaxed: “bulging” of apical surface c. Coiled tubular into lumen; (4) when tissue is stretched: may give d. Branched acinar appearance of stratified squamous epithelium, but nuclei are more round and there are fewer overall 2. Compound (branched ducts) layers of cells; also stratified squamous “undulates” a. Tubular Bladder Ureter with the underlying connective tissue but stretched b. Acinar transitional is more flat as is the underlying c. Tubulo-acinar connective tissue V. Summary Lab 4 – Epithelia and Glands IUSM – 2016 Summary I. Introduction II. Learning Objectives 1. Epithelium is polarized (different apical and basal surfaces), avascular tissue composed of III. Keywords sheets of closely aggregated cells (one or more layers) upon a basement membrane (basal IV. Slides lamina + reticular lamina); it covers body surfaces, lines body cavities, and forms glands. A. Epithelia 1. Simple 2. For simple epithelia, all the epithelial cells are directly attached to the basement membrane (i.e., only one cell layer thick); for epithelia, not all the cells are directly attached to the a. Simple squamous stratified basement membrane (i.e., more than one cell layer thick). b. Simple cuboidal c. Simple columnar 3. Epithelia are classified according to the shape of the cells (the most apical cells for stratified d. Pseudostratified columnar epithelia): squamous (flattened), cuboidal, columnar, and pseudostratified (simple but may 2. Stratified appear stratified). a. Stratified squamous b. Stratified cuboidal 4. Epithelial apical modifications include: microvilli (short, finger-like cytoplasmic processes c. Stratified columnar containing actin which may be visible as a brush/striated border), stereocilia (rare, long d. Transitional microvilli containing actin), and cilia (hair-like extensions of plasma membrane containing an B. Exocrine Glands axoneme – core of 9+2 doublets). 1. Simple (unbranched duct) 5. The type of epithelium (thickness, shape, and apical modifications) can be used in inferring the a. Tubular function of a tissue or organ. b. Branched tubular c. Coiled tubular 6. Intercellular junctions are seen in EM and include: tight/occluding junctions (apical; prevent d. Branched acinar substances passing down and between cells), anchoring junctions (zona adherens; hold cells 2. Compound (branched ducts) together and to basement membrane), and communicating junctions (channels allowing small a. Tubular molecules to pass between adjacent cells). b. Acinar c. Tubulo-acinar V. Summary Lab 4 – Epithelia and Glands IUSM – 2016 I. Introduction Summary (cont.) II. Learning Objectives 7. Glandular epithelium is specialized for secretion and classified according to how products are III. Keywords released: the secretory portions of exocrine glands maintain contact via ducts/tube onto the IV. Slides apical surface of the epithelium where the products are released; endocrine glands lack ducts so A. Epithelia secrete their products () into the surrounding connective tissue from which they enter 1. Simple the bloodstream. a. Simple squamous b. Simple cuboidal 8. Exocrine glands are either unicellular (goblet cells) or multicellular, which are further classified c. Simple columnar morphologically according to the branching of their ducts (simple – have unbranched ducts; d. Pseudostratified columnar compound – have branched ducts) and the configuration of their secretory portions (e.g., tubular 2. Stratified or acinar in shape). a. Stratified squamous 9. Exocrine glands may also be classified according to: (1) the nature of their secretory product b. Stratified cuboidal (serous glands produce watery, poorly-glycosylated or nonglycosylated proteins which generally c. Stratified columnar stain eosinophilic; mucous glands produce viscous, glycosylated proteins and oligosaccharides d. Transitional and stain with PAS but poorly in H&E), or (2) the mode of secretion (merocrine – via exocytosis B. Exocrine Glands of vesicular contents; apocrine – via membrane-coated vesicles, or holocrine – via rupture and 1. Simple (unbranched duct) expulsion of entire cellular contents). a. Tubular b. Branched tubular c. Coiled tubular d. Branched acinar 2. Compound (branched ducts) a. Tubular b. Acinar c. Tubulo-acinar V. Summary Lab 4 – Epithelia and Glands Appearance, Function, and Locations of Epithelial Tissues IUSM – 2016 I. Introduction Draw and Label Epithelium Functions Locations II. Learning Objectives (& possible apical modifications) III. Keywords IV. Slides Squamous A. Epithelia 1. Simple a. Simple squamous Cuboidal b. Simple cuboidal c. Simple columnar

d. Pseudostratified columnar Simple 2. Stratified Columnar a. Stratified squamous b. Stratified cuboidal c. Stratified columnar Pseudostratified d. Transitional B. Exocrine Glands 1. Simple (unbranched duct) Squamous a. Tubular b. Branched tubular c. Coiled tubular d. Branched acinar Cuboidal

2. Compound (branched ducts) Stratified a. Tubular

b. Acinar Transitional c. Tubulo-acinar V. Summary Lab 4 – Epithelia and Glands Epithelial Terminology Compare and Contrast IUSM – 2016 I. Introduction Terms Compare and Contrast (Similarities? Distinctive differences?) II. Learning Objectives III. Keywords Simple vs. Stratified IV. Slides epithelia A. Epithelia 1. Simple a. Simple squamous Microvilli vs. b. Simple cuboidal Stereocilia vs. Cilia c. Simple columnar d. Pseudostratified columnar Merocrine vs. 2. Stratified Apocrine vs. Holocrine secretion a. Stratified squamous b. Stratified cuboidal Mucous vs. Serous c. Stratified columnar acini d. Transitional B. Exocrine Glands Occluding vs. 1. Simple (unbranched duct) Anchoring vs. a. Tubular Communicating b. Branched tubular junctions c. Coiled tubular d. Branched acinar Parenchyma vs. Stroma 2. Compound (branched ducts) a. Tubular b. Acinar Brush border vs. c. Tubulo-acinar Terminal web V. Summary Lab 4 – Epithelia and Glands Exocrine Gland Morphology and Characteristics IUSM – 2016 I. Introduction II. Learning Objectives III. Keywords IV. Slides A. Epithelia 1. Simple a. Simple squamous b. Simple cuboidal c. Simple columnar d. Pseudostratified columnar 2. Stratified a. Stratified squamous b. Stratified cuboidal c. Stratified columnar d. Transitional B. Exocrine Glands 1. Simple (unbranched duct) a. Tubular b. Branched tubular c. Coiled tubular d. Branched acinar 2. Compound (branched ducts) a. Tubular b. Acinar c. Tubulo-acinar V. Summary