Safety Assessment of Hamamelis virginiana (Witch Hazel)-Derived Ingredients as Used in Cosmetics Status: Draft Report for Panel Review Release Date: August 18, 2017 Panel Meeting Date: September 11-12, 2017 The 2017 Cosmetic Ingredient Review Expert Panel members are: Chair, Wilma F. Bergfeld, M.D., F.A.C.P.; Donald V. Belsito, M.D.; Ronald A. Hill, Ph.D.; Curtis D. Klaassen, Ph.D.; Daniel C. Liebler, Ph.D.; James G. Marks, Jr., M.D.; Ronald C. Shank, Ph.D.; Thomas J. Slaga, Ph.D.; and Paul W. Snyder, D.V.M., Ph.D. The CIR Interim Director is Bart Heldreth, Ph.D. This report was prepared by Lillian C. Becker, Scientific Analyst/Writer. © Cosmetic Ingredient Review 1620 L Street, NW, Suite 1200 ♢ Washington, DC 20036-4702 ♢ ph 202.331.0651 ♢ fax 202.331.0088
[email protected] Distributed for Comment Only -- Do Not Cite or Quote Commitment & Credibility since 1976 MEMORANDUM To: CIR Expert Panel and Liaisons From: Lillian C. Becker, M.S. Scientific Analyst and Writer Date: August 18, 2017 Subject: Hamamelis virginiana (Witch Hazel)-Derived Ingredients Attached is the Draft Report of Hamamelis virginiana (Witch Hazel)-Derived Ingredients as used in cosmetics. [HamVir092017Rep] These eight ingredients are all derived from part(s) of the Hamamelis virginiana (Witch Hazel) plant. In July 2017, an SLR was issued with an invitation for data on these ingredients. Concentration of use data were submitted. [HamVir092017Data_1,2] Data on method of manufacture, impurities, in vitro dermal and ocular irritation on Hamamelis Virginiana (Witch Hazel) Bark/Leaf/Twig Extract and Hamamelis Virginiana (Witch Hazel) Extract, and an HRIPT of Hamamelis Virginiana (Witch Hazel) Water with negative results were also submitted.