Human Apoptosis Ref : AP1H1

Gene Name Symbol v-akt murine thymoma viral oncogene homolog 1 AKT1

BCL2-associated agonist of cell death BAD caspase 9, apoptosis-related cysteine peptidase CASP9

Fas ligand (TNF superfamily, member 6) FASLG receptor-interacting serine-threonine kinase 2 RIPK2 caspase 3, apoptosis-related cysteine peptidase CASP3 caspase 7, apoptosis-related cysteine peptidase CASP7 apoptotic peptidase activating factor 1 APAF1

BCL2-associated X protein BAX

BH3 interacting domain death agonist BID

BCL2-like 1 BCL2L1

B-cell CLL/lymphoma 2 BCL2 caspase 6, apoptosis-related cysteine peptidase CASP6 tumor protein p53 TP53 c-abl oncogene 1, non-receptor tyrosine kinase ABL1 growth arrest and DNA-damage-inducible, alpha GADD45A tumor protein p73 TP73 caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) CASP1 caspase 2, apoptosis-related cysteine peptidase CASP2 caspase 4, apoptosis-related cysteine peptidase CASP4 caspase 10, apoptosis-related cysteine peptidase CASP10

DNA fragmentation factor, 45kDa, alpha polypeptide DFFA caspase 14, apoptosis-related cysteine peptidase CASP14 caspase 8, apoptosis-related cysteine peptidase CASP8

CASP8 and FADD-like apoptosis regulator CFLAR

Fas (TNFRSF6)-associated via death domain FADD

Fas (TNF receptor superfamily, member 6) FAS tumor necrosis factor TNF baculoviral IAP repeat containing 2 BIRC2 tumor necrosis factor (ligand) superfamily, member 10 TNFSF10 tumor necrosis factor receptor superfamily, member 10a TNFRSF10A

Apoptosis SignArrays® AnyGenes® - 4 rue de la Chine - 75970 Paris Cedex 20 www.anygenes.com tumor necrosis factor receptor superfamily, member 25 TNFRSF25

TNFRSF1A-associated via death domain TRADD

TNF receptor-associated factor 2 TRAF2 tumor necrosis factor receptor superfamily, member 21 TNFRSF21 tumor necrosis factor receptor superfamily, member 11b TNFRSF11B insulin-like growth factor 1 receptor IGF1R

BCL2-interacting killer (apoptosis-inducing) BIK

BCL2-associated athanogene 4 BAG4 baculoviral IAP repeat containing 3 BIRC3 tumor necrosis factor receptor superfamily, member 1A TNFRSF1A

CASP2 and RIPK1 domain containing adaptor with death domain CRADD lymphotoxin alpha (TNF superfamily, member 1) LTA bifunctional apoptosis regulator BFAR

NLR family, apoptosis inhibitory protein NAIP baculoviral IAP repeat containing 6 BIRC6 baculoviral IAP repeat containing 8 BIRC8

BCL2/adenovirus E1B 19kDa interacting protein 1 BNIP1

BCL2/adenovirus E1B 19kDa interacting protein 2 BNIP2

BCL2/adenovirus E1B 19kDa interacting protein 3 BNIP3 v-raf murine sarcoma viral oncogene homolog B1 BRAF

CD40 ligand CD40LG nucleolar protein 3 (apoptosis repressor with CARD domain) NOL3

CD27 molecule CD27

BCL2-associated athanogene BAG1

BCL2-related protein A1 BCL2A1

BCL2-like 2 BCL2L2

X-linked inhibitor of apoptosis XIAP

BCL2-associated athanogene 3 BAG3

BCL2/adenovirus E1B 19kDa interacting protein 3-like BNIP3L cell death-inducing DFFA-like effector a CIDEA myeloid cell leukemia sequence 1 (BCL2-related) MCL1

BCL2-like 11 (apoptosis facilitator) BCL2L11

BCL2-antagonist/killer 1 BAK1

BCL2-associated transcription factor 1 BCLAF1 death-associated protein kinase 1 DAPK1 cell death-inducing DFFA-like effector b CIDEB harakiri, BCL2 interacting protein (contains only BH3 domain) HRK

Apoptosis SignArrays® AnyGenes® - 4 rue de la Chine - 75970 Paris Cedex 20 www.anygenes.com PYD and CARD domain containing PYCARD tumor necrosis factor receptor superfamily, member 9 TNFRSF9

CD70 molecule CD70 tumor necrosis factor (ligand) superfamily, member 8 TNFSF8 tumor protein p53 binding protein, 2 TP53BP2

TNF receptor-associated factor 3 TRAF3 caspase recruitment domain family, member 6 CARD6 caspase recruitment domain family, member 8 CARD8 caspase 5, apoptosis-related cysteine peptidase CASP5

TNF receptor-associated factor 4 TRAF4

CD40 molecule, TNF receptor superfamily member 5 CD40 lymphotoxin beta receptor (TNFR superfamily, member 3) LTBR

B-cell CLL/lymphoma 10 BCL10

BCL2-like 10 (apoptosis facilitator) BCL2L10 nucleotide-binding oligomerization domain containing 1 NOD1 tumor necrosis factor receptor superfamily, member 10b TNFRSF10B peptidylprolyl isomerase A (cyclophilin A) PPIA actin, beta ACTB

TATA box binding protein TBP beta-2-microglobulin B2M ribosomal protein, large, P0 RPLPO

Hypoxanthine guanine phosphoribosyl transferase I HPRT1

Transferrin receptor (p90, CD71) TFRC

Glucuronidase, beta GUSB

Positive control QC1

Positive control QC2

Negative control QC3

Negative control QC4

Reference genes

Controls

Apoptosis SignArrays® AnyGenes® - 4 rue de la Chine - 75970 Paris Cedex 20 www.anygenes.com