Military Exposures and the Aging Veteran What Long-Term Care Providers Need to Know
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Military Exposures and the Aging Veteran What Long-term Care Providers Need to Know Omowunmi Osinubi, MD, M.Sc. MBA., FRCA, ABIHM, IFM-CP, BCN. Director, Clinical Services War-related Illness & Injury Study Center Department of Veterans Affairs – New Jersey Healthcare System [email protected] The National Association of State Veterans Homes Summer Conference Denver, Colorado August 8, 2019 Office of Patient Care Services Post-Deployment Health Services War Related Illness and Injury Study Center The views expressed in this presentation are those of the presenters and do not necessarily reflect the position or policy of the Department of Veterans Affairs or the United States government. There are no financial conflicts of interest to disclose. Office of Patient Care Services Post-Deployment Health Services War Related Illness and Injury Study Center Presentation Outline • Introduction to VA Post Deployment Health Services (PDHS/WRIISC) • Vietnam War Exposures & VA Presumptive Conditions • Gulf War Exposures & VA Presumptive Conditions • Garrison exposures: – Camp Lejeune & VA Presumptive Conditions – Training-related exposures • Mental Health & Cognitive impacts of Military Exposures • Available Resources Office of Patient Care Services Post-Deployment Health Services War Related Illness and Injury Study Center Post Deployment Health Services Mission: • A VA-Delivered Core Service that assesses the impact of deployment/ environmental exposures on Veterans and develops related policy, research, education and health care strategies • PDHS consists of three interrelated Programs: – Environmental Exposure Epidemiology – Environmental Health (Pre-911 Programs / Post-911 Programs / Radiation dose evaluations) – The War Related Illness and Injury Study Center • WRIISC is a National VA Post-Deployment Health Program, established by Public Law 105-368, 105th Congress, 1998 4 Office of Patient Care Services Post-Deployment Health Services War Related Illness and Injury Study Center WRIISC LOCATIONS & SERVICE AREAS Office of Patient Care Services Post-Deployment Health Services War Related Illness and Injury Study Center WRIISC MODEL Research Research produces knowledge and evidence- supported interventions and tools that can improve patient care and can be packaged and disseminated through education activities. Education Clinical Care Education of patients and Observations from clinical care providers can improve patient lead to research questions and outcomes and identify gaps in testable hypotheses, highlight knowledge to be addressed gaps in provider and patient by research. knowledge. Office of Patient Care Services Post-Deployment Health Services War Related Illness and Injury Study Center TODAY’S VETERANS – AGING POPULATION 19.6 Million Veterans in The USA 55% of all Veterans are 60 years old or older M Younger than 30 1 M 33-44 years old 3.3 45-59 years old 5.7 M 60-74 years old 7.7 M 75 years or older 4.8 M 0 2 4 6 8 10 Office of Patient Care Services Post-Deployment Health Services War Related Illness and Injury Study Center THE VIETNAM WAR: 11/1/55 – 4/30/75 • Long, costly and divisive conflict • U.S. DoD estimates that for the years 1955–1975: – 2.8 million served in Vietnam – 3.4 million served in Southeast Asia – 8.7 million served worldwide. • More than 3 million people died – More than 58,000 Americans – More than half of the dead were Vietnamese civilians • January 1973 US & North Vietnam concluded peace agreement • Vietnam Veterans returned home to negative reactions - along with physical damage including the effects of exposure to the toxic herbicide Agent Orange. – https://www.history.com/topics/vietnam-war/vietnam-war-history Office of Patient Care Services Post-Deployment Health Services War Related Illness and Injury Study Center WHAT IS AGENT ORANGE (AO)? “Agent The dioxin Orange” was a by- An herbicide A mixture of Contained came from product of that was two TCDD orange strip the used to kill common (dioxins) on drums manufacture plants herbicides contaminant (Also other of the colors) herbicide Office of Patient Care Services Post-Deployment Health Services War Related Illness and Injury Study Center WHEN WERE HERBICIDES USED? • Herbicides used from 1961 to 1971 • Agent Orange 1965 – ‘70; Green, Pink, Purple ’61 – ‘65 • Agents White and Blue: 1960s – ‘71 • Agent Orange in Korea along DMZ from 1968 to 1971 ‘61 ‘65 ‘68 ‘69 ‘70 ‘71 Herbicide Agent Orange in Vietnam In Korea Office of Patient Care Services Post-Deployment Health Services War Related Illness and Injury Study Center WHY WAS AGENT ORANGE USED? • Tactical herbicides - used to defoliate forested and rural land • Goals of defoliation: – Deprive guerillas of cover – Deprive guerillas of their rural support and food supply • By destroying ability of peasants to support themselves in the countryside, forcing them to flee to U.S. dominated cities Office of Patient Care Services Post-Deployment Health Services War Related Illness and Injury Study Center WHAT WAS THE EXTENT OF HERBICIDE USE? • 20 million gallons of defoliant sprayed from aircraft • USAF Operation Ranch Hand: 6, 542 spraying missions • >20% of South Vietnam’s forest sprayed over 9 years • By 1971, 12% of total area of S. Vietnam sprayed Office of Patient Care Services Post-Deployment Health Services War Related Illness and Injury Study Center OTHER AGENT ORANGE EXPOSURE LOCATIONS • May have been exposed in: – Thailand near perimeter of certain bases ~1961-75 – Contaminated C-123 air planes from ~1969 – 86 – Herbicides stored or tested elsewhere – Brown Water if on land/inland waterways ~1962-75 Office of Patient Care Services Post-Deployment Health Services War Related Illness and Injury Study Center WHAT IS THE AGENT ORANGE ACT OF 1991? • Public Law 102-4 (Agent Orange Act of 1991) – Established presumption of exposure & service connection for diseases associated with herbicide exposure – Institute of Medicine (IOM) reviews Agent Orange research and makes scientific recommendations to VA – Secretary of VA uses IOM Reports to inform decisions regarding conditions to put on the VA List of conditions Presumed Related to Agent Orange. Office of Patient Care Services Post-Deployment Health Services War Related Illness and Injury Study Center VA PRESUMPTIONS: WHY DO WE HAVE THEM? • Lack of exposure data and real knowledge • Two-step presumption: If you were there…. You were exposed If you were exposed and develop one of the conditions…. It is related to the exposure Office of Patient Care Services Post-Deployment Health Services War Related Illness and Injury Study Center NATIONAL ACADEMIES OF MEDICINE (NAM) VETERANS & AGENT ORANGE REPORTS •Funded by VA to determine if health effects are associated with exposures to herbicides and dioxin. •Eleven reports published by Institute of Medicine (IOM), now called the National Academies of Medicine (NAS). •Update 11 published in Nov 2018 - available free online at: http://www.nationalacademies.org/h md/Reports/2018/veterans-and- Released in agent-orange-update-2018.aspx November 2018 Office of Patient Care Services Post-Deployment Health Services War Related Illness and Injury Study Center A O - TIME LIMITED PRESUMPTIVE CONDITIONS • Peripheral Neuropathy (early onset) • Porphyria Cutanea Tarda • Chloracne (or similar acneform disease) Office of Patient Care Services Post-Deployment Health Services War Related Illness and Injury Study Center AGENT ORANGE PRESUMPTIVE CONDITIONS: • Cancers: – Chronic B-Cell Leukemias – Hodgkin’s Disease – Non-Hodgkin Lymphoma – Multiple Myeloma – Some Soft Tissue Sarcomas – Prostate Cancer – Respiratory Cancers: • Lung, larynx, trachea, bronchus Office of Patient Care Services Post-Deployment Health Services War Related Illness and Injury Study Center AO PRESUMPTIVES: COMMON AND UNCOMMON • Common: - Parkinson’s Disease - Ischemic Heart Disease - Diabetes Type 2 • Uncommon: - AL Amyloidosis - Spina Bifida (Vietnam or Korean DMZ) - Birth Defects (children of female Vietnam Vets) Office of Patient Care Services Post-Deployment Health Services War Related Illness and Injury Study Center BLUE WATER NAVY (PROCOPIO V. WILKIE) • The term refers to those vessels usually navigating outside the territorial seas of Vietnam. – BWN within 12 miles from shore • Blue water Veteran with prostate cancer and Type II diabetes filed a law suit against the VA • U.S. Court of Appeals for the https://www.militarytimes.com/news/pentago Federal Circuit has ruled that VA n-congress/2019/01/29/court-rules-va-must- pay-disability-benefits-to-blue-water-vietnam- must pay disability benefits to veterans/ ‘blue water’ Navy Vietnam veterans Office of Patient Care Services Post-Deployment Health Services War Related Illness and Injury Study Center www.va.gov/opa/pressrel/pressrelease.cfm?id=5280 Office of Patient Care Services Post-Deployment Health Services War Related Illness and Injury Study Center WHAT’S AHEAD: NATIONAL ACADEMIES OF SCIENCE • Veterans and Agent Orange Update 2014: – Limited evidence of suggestive association for: • Bladder Cancer • Hypothyroidism • “Parkinson-like Symptoms” • Veterans and Agent Orange: Update 2018: – Sufficient evidence of association for • Hypertension • Monoclonal gammopathy of undetermined significance (MGUS) Office of Patient Care Services Post-Deployment Health Services War Related Illness and Injury Study Center WHAT’S AHEAD: • NAS Report on Intergenerational Effects of Toxic Exposures from Military Service – Gulf War Veterans – Vietnam Veterans – Recommend a strategy for studying any effects in children