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Human Recombinant Protein – TP710343 OriGene Technologies, Inc. 9620 Medical Center Drive, Ste 200 Rockville, MD 20850, US Phone: +1-888-267-4436 [email protected] EU: [email protected] CN: [email protected] Product datasheet for TP710343 H2AW (NM_033445) Human Recombinant Protein Product data: Product Type: Recombinant Proteins Description: Purified recombinant protein of Human histone cluster 3, H2a (HIST3H2A), full length, with with C-terminal DDK tag, expressed in sf9, 20ug Species: Human Expression Host: Sf9 Tag: C-DDK Predicted MW: 13.9 kDa Concentration: >50 ug/mL as determined by microplate BCA method Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining Buffer: 50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol Storage: Store at -80°C. Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. RefSeq: NP_254280 Locus ID: 92815 UniProt ID: Q7L7L0 RefSeq Size: 496 Cytogenetics: 1q42.13 RefSeq ORF: 390 Synonyms: HIST3H2A Summary: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene contain a palindromic termination element. [provided by RefSeq, Aug 2015] This product is to be used for laboratory only. Not for diagnostic or therapeutic use. View online » ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 1 / 2 H2AW (NM_033445) Human Recombinant Protein – TP710343 Protein Pathways: Systemic lupus erythematosus Product images: This product is to be used for laboratory only. Not for diagnostic or therapeutic use. ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 2 / 2.
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    PrimePCR™Assay Validation Report Gene Information Gene Name histone cluster 3, H2a Gene Symbol HIST3H2A Organism Human Gene Summary Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A H2B H3 and H4). The chromatin fiber is further compacted through the interaction of a linker histone H1 with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene contain a palindromic termination element. Gene Aliases MGC3165 RefSeq Accession No. NC_000001.10, NT_167186.1 UniGene ID Hs.26331 Ensembl Gene ID ENSG00000181218 Entrez Gene ID 92815 Assay Information Unique Assay ID qHsaCED0047450 Assay Type SYBR® Green Detected Coding Transcript(s) ENST00000233840, ENST00000360657, ENST00000259791, ENST00000602637, ENST00000377791, ENST00000377831, ENST00000341023, ENST00000303910, ENST00000359193, ENST00000377459, ENST00000358739, ENST00000333151, ENST00000330180, ENST00000357320, ENST00000359611, ENST00000511601, ENST00000260008, ENST00000369161, ENST00000369159, ENST00000366695, ENST00000543095, ENST00000389961, ENST00000439727, ENST00000583968, ENST00000580456 Amplicon Context Sequence GTGGCTCTCCGTCTTCTTGGGCAGCAGTACGGCCTGGATGTTGGGCAGGACGC CACCCTGCGCGATGGTCACGCGGCCCAGCAGCTTGTTGAGCTCCTCGTCGTTG CGGATGGCCAGCTGCAGGTGGCGCGGGATGATGCGCGTCTTCTTGTTGTCGCG
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    Histone H2A (Phospho Ser129) Polyclonal Antibody Catalog No : YM3277 Reactivity : Human,Mouse,Rat Applications : WB Gene Name : HIST1H2AG/HIST1H2AI/HIST1H2AK/HIST1H2AL/HIST1H2AM/HIST2H2AA3 /HIST2H2AA4/HIST3H2A Protein Name : Histone H2A type 1/Histone H2A type 2/Histone H2A type 3 Human Gene Id : 8329/8330/8332/8336/8969/723790/8337/92815 Human Swiss Prot P0C0S8/Q6FI13/Q7L7L0 No : Mouse Gene Id : 319164/15267/319162 Rat Gene Id : 365877/64646 Rat Swiss Prot No : P02262/P0CC09/Q4FZT6 Immunogen : Synthetic Peptide of Histone H2A (Phospho Ser129) Specificity : The antibody detects endogenous Histone H2A (Phospho Ser129) protein. Formulation : PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol. Source : Rabbit Dilution : WB: 1:1000-2000 Purification : The antibody was affinity-purified from rabbit antiserum by affinity- chromatography using specific immunogen. Storage Stability : -20°C/1 year Molecularweight : 14091/14095/14121 1 / 3 Observed Band : 14 Cell Pathway : Systemic lupus erythematosus, Background : histone cluster 1 H2A family member i(HIST1H2AI) Homo sapiens Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element.
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