The University of Sheffield CALENDAR 2019-20
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Metabolomic Assessment of Dietary Interventions in Obesity by Capillary Electrophoresis Mass Spectrometry
Metabolomic Assessment of Dietary Interventions in Obesity by Capillary Electrophoresis Mass Spectrometry Metabolomic Assessment of Dietary Interventions in Obesity by Capillary Electrophoresis Mass Spectrometry By Karen Phoebe Lam, H.B.Sc., M.Sc. A Thesis Submitted to the School of Graduate Studies in Partial Fulfillment of the Requirements for the Degree Doctor of Philosophy McMaster University © Copyright by Karen Phoebe Lam, July 2018 Doctor of Philosophy (2018) McMaster University (Department of Chemisty & Chemical Biology) Hamilton, Ontario TITLE: Metabolomic Assessment of Dietary Interventions in Obesity by Capillary Electrophoresis Mass Spectrometry AUTHOR: Karen Phoebe Lam, H.B.Sc. (University of Toronto), M.Sc. (McMaster University) SUPERVISOR: Professor Philip Britz-McKibbin NUMBER OF PAGES: xxix, 347 ii Abstract Capillary electrophoresis mass spectrometry (CE-MS) is a versatile instrumental method for metabolomics, which allows for comprehensive metabolite profiling of volume-limited biological specimens in order to better understand the molecular mechanisms associated with chronic diseases, including an alarming epidemic of obesity worldwide. Multiplexed CE separations enable high-throughput metabolite screening with quality assurance to prevent false discoveries when combined with rigorous method validation, robust experimental designs, complementary statistical methods, and high-resolution tandem mass spectrometry (MS/MS) for unknown metabolite identification. In this thesis, multiplexed CE-MS technology is applied for both targeted and untargeted metabolite profiling of various biological fluids, including covalently bound thiol-protein conjugates, as well as free circulating metabolites in serum and plasma, and excreted/bio-transformed compounds in urine due to complex host-gut microflora co-metabolism. This work was applied to characterize aberrant metabolic responses of obese subjects in response to dietary challenges, and measure the benefits of dietary interventions that reduce adiposity without deleterious muscle loss. -
Crystallography News British Crystallographic Association
Crystallography News British Crystallographic Association Issue No. 100 March 2007 ISSN 1467-2790 BCA Spring Meeting 2007 - Canterbury p8-17 Patrick Tollin (1938 - 2006) p7 The Z’ > 1 Phenomenon p18-19 History p21-23 Meetings of Interest p32 March 2007 Crystallography News Contents 2 . From the President 3 . Council Members 4 . BCA Letters to the Editor 5 Administrative Office, . Elaine Fulton, From the Editor 6 Northern Networking Events Ltd. 7 1 Tennant Avenue, Puzzle Corner College Milton South, . East Kilbride, Glasgow G74 5NA Scotland, UK Patrick Tollin (1938 - 2006) 8-17 Tel: + 44 1355 244966 Fax: + 44 1355 249959 . e-mail: [email protected] BCA 2007 Spring Meeting 16-17 . CRYSTALLOGRAPHY NEWS is published quarterly (March, June, BCA 2007 Meeting Timetable 18-19 September and December) by the British Crystallographic Association, . and printed by William Anderson and Sons Ltd, Glasgow. Text should The Z’ > 1 Phenomenon 20 preferably be sent electronically as MSword documents (any version - . .doc, .rtf or .txt files) or else on a PC disk. Diagrams and figures are most IUCr Computing Commission 21-23 welcome, but please send them separately from text as .jpg, .gif, .tif, or .bmp files. Items may include technical articles, news about people (e.g. History . 24-27 awards, honours, retirements etc.), reports on past meetings of interest to crystallographers, notices of future meetings, historical reminiscences, Groups .......................................................... 28-31 letters to the editor, book, hardware or software reviews. Please ensure that items for inclusion in the June 2007 issue are sent to the Editor to arrive Meetings . 32 before 25th April 2007. -
Haemophilia: Recent History of Clinical Management
HAEMOPHILIA: RECENT HISTORY OF CLINICAL MANAGEMENT The transcript of a Witness Seminar held at the Wellcome Institute for the History of Medicine, London, on 10 February 1998 Edited by D A Christie and E M Tansey HAEMOPHILIA: RECENT HISTORY OF CLINICAL MANAGEMENT Participants Dr Derek Bangham Professor Ilsley Ingram Dr Ethel Bidwell Dr Peter Jones Sir Christopher Booth Professor Christine Lee (Chair) Dr Brian Colvin Dr James Matthews Dr Angela Dike Mrs Riva Miller Mr Ross Dike Dr Charles Rizza Dr Helen Dodsworth Rev Alan Tanner Professor Stuart Douglas* Dr Tilli Tansey Professor Robert Duthie Professor Edward Tuddenham Dr David Evans Dr David Tyrrell Dr Sheila Howarth Mr Clifford Welch Others present at the meeting: Dr Trevor Barrowcliffe, Ms Jacqui Marr, Dr J K Smith, Miss Rosemary Spooner Apologies: Professor Jean-Pierre Allain, Dr Donald Bateman, Dr Rosemary Biggs, Mrs Peggy Britten,** Professor Judith Chessells, Dr Audrey Dawson, Mr Ron Hutton, Professor Ralph Kekwick, Professor Sir David Weatherall *Deceased 15 November 1998 **Deceased 1 March 1999 2 Haemophilia: Recent history Professor Christine Lee:1 I think haemophilia is one of the best areas of clinical medicine where we have seen a very rapid introduction of scientific discovery into clinical practice. All of us who work on haemophilia realize that this has gone on very much with cooperation between the patients and the scientists and the doctors. I first saw haemophilia in 1967 when I was a medical student in Oxford and we were doing our orthopaedics at the Nuffield Orthopaedic Hospital. I have a very clear memory of a ward of little boys with their legs strung up, their arms strung up, and I think there was a schoolroom nearby. -
Clinical Pharmacology in the UK, C. 1950–2000: Industry and Regulation
CLINICAL PHARMACOLOGY IN THE UK, c. 1950–2000: INDUSTRY AND REGULATION The transcript of a Witness Seminar held by the Wellcome Trust Centre for the History of Medicine at UCL, London, on 25 September 2007 Edited by L A Reynolds and E M Tansey Volume 34 2008 ©The Trustee of the Wellcome Trust, London, 2008 First published by the Wellcome Trust Centre for the History of Medicine at UCL, 2008 The Wellcome Trust Centre for the History of Medicine at UCL is funded by the Wellcome Trust, which is a registered charity, no. 210183. ISBN 978 085484 118 9 All volumes are freely available online at: www.history.qmul.ac.uk/research/modbiomed/wellcome_witnesses/ Please cite as: Reynolds L A, Tansey E M. (eds) (2008) Clinical Pharmacology in the UK c.1950-2000: Industry and regulation. Wellcome Witnesses to Twentieth Century Medicine, vol. 34. London: Wellcome Trust Centre for the History of Medicine at UCL. CONTENTS Illustrations and credits v Abbreviations vii Witness Seminars: Meetings and publications; Acknowledgements E M Tansey and L A Reynolds ix Introduction Professor Parveen Kumar xxiii Transcript Edited by L A Reynolds and E M Tansey 1 References 73 Biographical notes 89 Glossary 103 Index 109 ILLUSTRATIONS AND CREDITS Figure 1 AstraZeneca Clinical Trials Unit, South Manchester. Reproduced by permission of AstraZeneca. 6 Figure 2 A summary of the organization of clinical trials. Adapted from www.clinicaltrials.gov/ct2/info/glossary (visited 1 May 2008). 10 Figure 3 Clinical trial certificates (CTC) and clinical trial exemption (CTX), 1972–1985. Adapted from Speirs (1983) and Speirs (1984). -
Harper, Peter: Transcript of a Video Interview (06-Jun-2015)
History of Modern Biomedicine Research Group School of History, Queen Mary University of London Mile End Road, London E1 4NS website: www.histmodbiomed.org VIDEO INTERVIEW TRANSCRIPT Harper, Peter: transcript of a video interview (06-Jun-2015) Interviewer: Tilli Tansey Transcriber: Debra Gee Editors: Tilli Tansey, Alan Yabsley Date of publication: 20-Mar-2017 Date and place of interview: 06-Jun-2015; Glasgow Publisher: Queen Mary University of London Collection: History of Modern Biomedicine Interviews (Digital Collection) Reference: e2017093 Number of pages: 4 DOI: 10.17636/01021439 Acknowledgments: The project management of Mr Adam Wilkinson is gratefully acknowledged. The History of Modern Biomedicine Research Group is funded by the Wellcome Trust, which is a registered charity (no. 210183). The current interview has been funded by the Wellcome Trust Strategic Award entitled “Makers of modern biomedicine: testimonies and legacy” (2012-2017; awarded to Professor Tilli Tansey). Citation: Tansey E M (intvr); Tansey E M, Yabsley A (eds) (2017) Harper, Peter: transcript of a video interview (06-Jun- 2015). History of Modern Biomedicine Interviews (Digital Collection), item e2017093. London: Queen Mary University of London. Related resources: items 2017094 - 2017099, History of Modern Biomedicine Interviews (Digital Collection) Note: Video interviews are conducted following standard oral history methodology, and have received ethical approval (reference QMREC 0642). Video interview transcripts are edited only for clarity and factual accuracy. Related material has been deposited in the Wellcome Library. © The Trustee of the Wellcome Trust, London, 2017 History of Modern Biomedicine Interviews (Digital Collection) - Harper, P e2017093 | 2 Harper, Peter: transcript of a video interview (06-Jun-2015)* Biography: Professor Peter Harper (b. -
2. Anthraphane Monomer 23
Research Collection Doctoral Thesis Anthraphanes: a New Class of Potential Monomers for the Synthesis of Two-Dimensional Polymers Author(s): Servalli, Marco Publication Date: 2016 Permanent Link: https://doi.org/10.3929/ethz-a-010832536 Rights / License: In Copyright - Non-Commercial Use Permitted This page was generated automatically upon download from the ETH Zurich Research Collection. For more information please consult the Terms of use. ETH Library DISS. ETH NO. 23866 Anthraphanes: a New Class of Potential Monomers for the Synthesis of Two-Dimensional Polymers A thesis submitted to attain the degree of DOCTOR OF SCIENCES of ETH ZURICH (Dr. sc. ETH Zurich) presented by MARCO SERVALLI MSc, ETH Zurich Chemistry born on 10.07.1986 citizen of Bioggio (TI), Switzerland accepted on the recommendation of Prof. Dr. A. Dieter Schlüter, examiner Prof. Dr. Joost VandeVondele, co-examiner Prof. Dr. Peter Walde, co-examiner Dr. Michael Wörle, co-examiner 2016 ACKNOWLEDGEMENTS Acknowledgements Doing a PhD and writing a thesis is not a stand-alone matter and involves the collaboration of many people. I would like to start my acknowledgements from the scientific and work-related point of view: At first, I would like to thank Prof. A. Dieter Schlüter, for offering me the chance to work on the stimulating, fascinating and challenging topic of two-dimensional polymers. Challenging projects deal specially with a lot of frustration and I therefore appreciate the continuous support I received from him during my PhD, in terms of scientific and non-scientific discussion, as well as the essential ongoing motivation to not give up and to keep pursuing my objectives. -
Women Physiologists
Women physiologists: Centenary celebrations and beyond physiologists: celebrations Centenary Women Hodgkin Huxley House 30 Farringdon Lane London EC1R 3AW T +44 (0)20 7269 5718 www.physoc.org • journals.physoc.org Women physiologists: Centenary celebrations and beyond Edited by Susan Wray and Tilli Tansey Forewords by Dame Julia Higgins DBE FRS FREng and Baroness Susan Greenfield CBE HonFRCP Published in 2015 by The Physiological Society At Hodgkin Huxley House, 30 Farringdon Lane, London EC1R 3AW Copyright © 2015 The Physiological Society Foreword copyright © 2015 by Dame Julia Higgins Foreword copyright © 2015 by Baroness Susan Greenfield All rights reserved ISBN 978-0-9933410-0-7 Contents Foreword 6 Centenary celebrations Women in physiology: Centenary celebrations and beyond 8 The landscape for women 25 years on 12 "To dine with ladies smelling of dog"? A brief history of women and The Physiological Society 16 Obituaries Alison Brading (1939-2011) 34 Gertrude Falk (1925-2008) 37 Marianne Fillenz (1924-2012) 39 Olga Hudlická (1926-2014) 42 Shelagh Morrissey (1916-1990) 46 Anne Warner (1940–2012) 48 Maureen Young (1915-2013) 51 Women physiologists Frances Mary Ashcroft 56 Heidi de Wet 58 Susan D Brain 60 Aisah A Aubdool 62 Andrea H. Brand 64 Irene Miguel-Aliaga 66 Barbara Casadei 68 Svetlana Reilly 70 Shamshad Cockcroft 72 Kathryn Garner 74 Dame Kay Davies 76 Lisa Heather 78 Annette Dolphin 80 Claudia Bauer 82 Kim Dora 84 Pooneh Bagher 86 Maria Fitzgerald 88 Stephanie Koch 90 Abigail L. Fowden 92 Amanda Sferruzzi-Perri 94 Christine Holt 96 Paloma T. Gonzalez-Bellido 98 Anne King 100 Ilona Obara 102 Bridget Lumb 104 Emma C Hart 106 Margaret (Mandy) R MacLean 108 Kirsty Mair 110 Eleanor A. -
Wellcome Witnesses to Twentieth Century Medicine: Volume 2 Tansey, EM; Christie, DA; Reynolds, LA
View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by Queen Mary Research Online Wellcome Witnesses to Twentieth Century Medicine: Volume 2 Tansey, EM; Christie, DA; Reynolds, LA For additional information about this publication click this link. http://qmro.qmul.ac.uk/jspui/handle/123456789/2746 Information about this research object was correct at the time of download; we occasionally make corrections to records, please therefore check the published record when citing. For more information contact [email protected] WELLCOME WITNESSES TO TWENTIETH CENTURY MEDICINE _____________________________________________________________________________ MAKING THE HUMAN BODY TRANSPARENT: THE IMPACT OF NUCLEAR MAGNETIC RESONANCE AND MAGNETIC RESONANCE IMAGING _________________________________________________ RESEARCH IN GENERAL PRACTICE __________________________________ DRUGS IN PSYCHIATRIC PRACTICE ______________________ THE MRC COMMON COLD UNIT ____________________________________ WITNESS SEMINAR TRANSCRIPTS EDITED BY: E M TANSEY D A CHRISTIE L A REYNOLDS Volume Two – September 1998 ©The Trustee of the Wellcome Trust, London, 1998 First published by the Wellcome Trust, 1998 Occasional Publication no. 6, 1998 The Wellcome Trust is a registered charity, no. 210183. ISBN 978 186983 539 1 All volumes are freely available online following the links to Publications/Wellcome Witnesses at www.ucl.ac.uk/histmed Please cite as : Tansey E M, Christie D A, Reynolds L A. (eds) (1998) Wellcome Witnesses to -
Looking at the Unborn: Hi S to R I Ca L As P E C T S of Ob S T E T R I C Ult R a S O U N D
Wellcome Witnesses to Twentieth Century Medicine LOOKING AT THE UNBORN: HI S TO R I CA L AS P E C T S OF OB S T E T R I C ULT R A S O U N D Volume 5 – January 2000 A Witness Seminar held at the Wellcome Institute for the History of Medicine, London, on 10 March 1998 Witness Seminar Transcript edited by E M Tansey and D A Christie ©The Trustee of the Wellcome Trust, London, 2000 First published by the Wellcome Trust, 2000 The Wellcome Trust is a registered charity, no. 210183. ISBN 978 184129 011 9 All volumes are freely available online at: www.history.qmul.ac.uk/research/modbiomed/wellcome_witnesses/ Please cite as: Tansey E M, Christie D A. (eds) (2000) Looking at the Unborn: Historical aspects of obstetric ultrasound. Wellcome Witnesses to Twentieth Century Medicine, vol. 5. London: Wellcome Trust. Key Front cover photographs, L to R from the top: Dr Tony Whittingham Mr Usama Abdulla, Mr Thomas Brown, Mr Demetrios Economides Professor Charles Whitfield, Dr Margaret McNay Dr James Willocks, Mrs Lois Reynolds Dr Marcolm Nicolson, Professor Norman McDicken Mr John Fleming, Dr Angus Hall (chair) Mr Thomas Brown, Dr Tony Whittingham Mr Usama Abdulla, Professor Peter Wells Back cover photographs, L to R from the top: Mr Thomas Brown Audience Dr Malcolm Nicolson, Dr Angus Hall (chair) : Professor Norman McDicken, Mrs Alix Donald Dr Norman Slark Professor John MacVicar Dr Angus Hall (chair) CONTENTS Introduction E M Tansey i Transcript 1 List of plates Figure 1. Ian Donald. 6 Figure 2. -
201120 111111
Instituto de Física de São Carlos Universidade de São Paulo Departamento de Física e Ciência dos Materiais RELATÓRIO DE ATIVIDADES 2020201120 111111 CChheeffee::: PPPPPPrrrrrrrrrooooooffffff......... DDDDDDrrrrrrr......... LLLLLLuuuuuuiiiiiiiiizzzzzz AAAAAAggggggoooooossssssttttttiiiiiiiiinnnnnnhhhhhhoooooo FFFFFFeeeeeerrrrrrrrrrrrrrrrrreeeeeeiiiiiiiiirrrrrrrrraaaaaa SSuupplleennttee::: PPPPPPrrrrrrrooooooffffff......... DDDDDDrrrrrrr......... LLLLLLuuuuuuiiiiiiiiissssss GGGGGGuuuuuussssssttttttaaaaaavvvvvvoooooo MMMMMMaaaaaarrrrrrrccccccaaaaaassssssssssssaaaaaa Ficha catalográfica elaborada pelo Serviço de Biblioteca e Informação Universidade de São Paulo. Instituto de Física de São Carlos. Relatório de atividades do ano de 2011 do Departamento de Física e Ciências dos Materiais/IFSC/USP./Organizado por Isabel Rosani Constantino...[ et al]. São Carlos: Departamento de Física e Ciência dos Materiais, 2012. 320p. 1.Relatório de atividades. I. Constantino, Isabel Rosani. II. Cagnin, Cristiane A. III. Lopes, Yvone A. B. IV. Monzane, Thaís Fernanda G. S. V. Oliveira, Rosangela M. M. VI. Pereira, Daniel F. VII. Reis, Simone F. VIII. Sertori, Isabel C. De Vitro. IX. Signini, Érica R. F. X.Título. INTRODUÇÃO a) Perfiill do Departamento de Físiica e Ciiênciia dos Materiiaiis ii b) Atiiviidades de Ensiino iiv c) Produção Técniico-Ciientífiica v d) Orientações e Teses Defendiidas iix e) Atiiviidades de Extensão xiiii f) Recursos Fiinanceiiros Obtiidos xiiii g) Resumo Quantiitatiivo da Produção Ciientífiica xv h) Atiiviidades de Ensiino e Pesquiisa -
Human Genetics 1990–2009
Portfolio Review Human Genetics 1990–2009 June 2010 Acknowledgements The Wellcome Trust would like to thank the many people who generously gave up their time to participate in this review. The project was led by Liz Allen, Michael Dunn and Claire Vaughan. Key input and support was provided by Dave Carr, Kevin Dolby, Audrey Duncanson, Katherine Littler, Suzi Morris, Annie Sanderson and Jo Scott (landscaping analysis), and Lois Reynolds and Tilli Tansey (Wellcome Trust Expert Group). We also would like to thank David Lynn for his ongoing support to the review. The views expressed in this report are those of the Wellcome Trust project team – drawing on the evidence compiled during the review. We are indebted to the independent Expert Group, who were pivotal in providing the assessments of the Wellcome Trust’s role in supporting human genetics and have informed ‘our’ speculations for the future. Finally, we would like to thank Professor Francis Collins, who provided valuable input to the development of the timelines. The Wellcome Trust is a charity registered in England and Wales, no. 210183. Contents Acknowledgements 2 Overview and key findings 4 Landmarks in human genetics 6 1. Introduction and background 8 2. Human genetics research: the global research landscape 9 2.1 Human genetics publication output: 1989–2008 10 3. Looking back: the Wellcome Trust and human genetics 14 3.1 Building research capacity and infrastructure 14 3.1.1 Wellcome Trust Sanger Institute (WTSI) 15 3.1.2 Wellcome Trust Centre for Human Genetics 15 3.1.3 Collaborations, consortia and partnerships 16 3.1.4 Research resources and data 16 3.2 Advancing knowledge and making discoveries 17 3.3 Advancing knowledge and making discoveries: within the field of human genetics 18 3.4 Advancing knowledge and making discoveries: beyond the field of human genetics – ‘ripple’ effects 19 Case studies 22 4. -
The University of Sheffield CALENDAR 2020-21
The University of Sheffield CALENDAR 2021-22 Charter, Statutes, General Regulations and Information NOTE The Regulations are reviewed and revised by Council and Senate, as relevant. While every effort has been made to ensure the accuracy of the information given in this publication, changes may need to be made between the date of publication and the time the student embarks on a programme of study. This publication is correct as at the time of print. ENQUIRIES All enquiries should be addressed to: University Secretary’s Office University of Sheffield Sheffield S10 2TN Telephone: 0114 222 2000 Email: [email protected] Printed by The University Print Service Published by the University of Sheffield CONTENTS Dates of Semesters 5 Historical Note 6 Arms 9 Charter 10 Statutes 12 Regulations of the Council 16 I Responsibility for Creation and Amendment of Regulations 16 II The Council 17 III Scheme of Council Delegation 23 IV The Auditor 37 V The Members of the University 38 VI The University Officers 39 VII The Dismissal and Removal from Office of the President & Vice-Chancellor 42 VIII Definitions 43 IX The Senate 45 X The Faculties 48 XI Extra-Faculty Learning and Teaching Committee 50 XII The Conferment and Withdrawal of Degrees 51 XIII The Execution of Contracts and Deeds 52 Regulations of the Senate 54 XIV General University Regulations 54 XV General Regulations for First Degrees 70 XVI General Regulations for Higher Degrees, Postgraduate Diplomas and Postgraduate 79 Certificates General Regulations for Higher Degrees by Research