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Metabolomic Assessment of Dietary Interventions in Obesity by Capillary Electrophoresis Mass Spectrometry
Metabolomic Assessment of Dietary Interventions in Obesity by Capillary Electrophoresis Mass Spectrometry Metabolomic Assessment of Dietary Interventions in Obesity by Capillary Electrophoresis Mass Spectrometry By Karen Phoebe Lam, H.B.Sc., M.Sc. A Thesis Submitted to the School of Graduate Studies in Partial Fulfillment of the Requirements for the Degree Doctor of Philosophy McMaster University © Copyright by Karen Phoebe Lam, July 2018 Doctor of Philosophy (2018) McMaster University (Department of Chemisty & Chemical Biology) Hamilton, Ontario TITLE: Metabolomic Assessment of Dietary Interventions in Obesity by Capillary Electrophoresis Mass Spectrometry AUTHOR: Karen Phoebe Lam, H.B.Sc. (University of Toronto), M.Sc. (McMaster University) SUPERVISOR: Professor Philip Britz-McKibbin NUMBER OF PAGES: xxix, 347 ii Abstract Capillary electrophoresis mass spectrometry (CE-MS) is a versatile instrumental method for metabolomics, which allows for comprehensive metabolite profiling of volume-limited biological specimens in order to better understand the molecular mechanisms associated with chronic diseases, including an alarming epidemic of obesity worldwide. Multiplexed CE separations enable high-throughput metabolite screening with quality assurance to prevent false discoveries when combined with rigorous method validation, robust experimental designs, complementary statistical methods, and high-resolution tandem mass spectrometry (MS/MS) for unknown metabolite identification. In this thesis, multiplexed CE-MS technology is applied for both targeted and untargeted metabolite profiling of various biological fluids, including covalently bound thiol-protein conjugates, as well as free circulating metabolites in serum and plasma, and excreted/bio-transformed compounds in urine due to complex host-gut microflora co-metabolism. This work was applied to characterize aberrant metabolic responses of obese subjects in response to dietary challenges, and measure the benefits of dietary interventions that reduce adiposity without deleterious muscle loss. -
Crystallography News British Crystallographic Association
Crystallography News British Crystallographic Association Issue No. 100 March 2007 ISSN 1467-2790 BCA Spring Meeting 2007 - Canterbury p8-17 Patrick Tollin (1938 - 2006) p7 The Z’ > 1 Phenomenon p18-19 History p21-23 Meetings of Interest p32 March 2007 Crystallography News Contents 2 . From the President 3 . Council Members 4 . BCA Letters to the Editor 5 Administrative Office, . Elaine Fulton, From the Editor 6 Northern Networking Events Ltd. 7 1 Tennant Avenue, Puzzle Corner College Milton South, . East Kilbride, Glasgow G74 5NA Scotland, UK Patrick Tollin (1938 - 2006) 8-17 Tel: + 44 1355 244966 Fax: + 44 1355 249959 . e-mail: [email protected] BCA 2007 Spring Meeting 16-17 . CRYSTALLOGRAPHY NEWS is published quarterly (March, June, BCA 2007 Meeting Timetable 18-19 September and December) by the British Crystallographic Association, . and printed by William Anderson and Sons Ltd, Glasgow. Text should The Z’ > 1 Phenomenon 20 preferably be sent electronically as MSword documents (any version - . .doc, .rtf or .txt files) or else on a PC disk. Diagrams and figures are most IUCr Computing Commission 21-23 welcome, but please send them separately from text as .jpg, .gif, .tif, or .bmp files. Items may include technical articles, news about people (e.g. History . 24-27 awards, honours, retirements etc.), reports on past meetings of interest to crystallographers, notices of future meetings, historical reminiscences, Groups .......................................................... 28-31 letters to the editor, book, hardware or software reviews. Please ensure that items for inclusion in the June 2007 issue are sent to the Editor to arrive Meetings . 32 before 25th April 2007. -
May 2005 the Canadian Quandary Introduction by William Watson
Draft: May 2005 The Canadian Quandary Introduction by William Watson1 What a treat is in store for readers of these essays. Harry Gordon Johnson was one of the best economists of the 1950s and 1960s, not just in Canada but worldwide. Had he not died young, in 1977, only 17 days short of his 54th birthday, he might have won the Nobel Prize. And yet he was also a controversialist of the first rank. When he chose to be “unbuttoned,” as he put it, he wrote with a caustic and dismissive elegance. In some passages of The Canadian Quandary it is as if H. L. Mencken has left Baltimore and come to Canada to take up economics. In this collection of Johnson’s Canadian writings from the Diefenbaker years, 1957 to 1963, the most frequent victims of his derision are Canadian economic nationalists, led in that era by Walter Gordon, Lester Pearson’s first finance minister and author of the Gordon Royal Commission Report of 1957. For most non-economist readers it is as a contribution to the postwar debate on Canadian nationalism that this volume will mainly be of interest. Although the nationalists’ views eventually came to dominate Canada’s universities, economics departments sometimes excepted, and influence the Trudeau government, when they were first bruited, in the late 1950s and early 1960s, they were frequently opposed. Johnson was one of their strongest critics. The heyday of left-wing nationalism is now past, of course. Trudeau’s National Energy Policy and Foreign Investment Review Agency have long since been dismantled or neutered. -
Two out of Three Ain't Bad | the Economist
Two out of three ain’t bad | The Economist 26.8.16 10:51 The Mundell-Fleming trilemma Two out of three ain’t bad A fixed exchange rate, monetary autonomy and the free flow of capital are incompatible, according to the last in our series of big economic ideas Aug 27th 2016 | From the print edition HILLEL THE ELDER, a first-century religious leader, was asked to summarise the Torah while standing on one leg. “That which is hateful to you, do not do to your fellow. That is the whole Torah; the rest is commentary,” he replied. Michael Klein, of Tufts University, has written that the insights of international macroeconomics (the study of trade, the balance-of-payments, exchange rates and so on) might be similarly distilled: “Governments face the policy trilemma; the rest is commentary.” The policy trilemma, also known as the impossible or inconsistent trinity, says a country must choose between free capital mobility, exchange-rate management and monetary autonomy (the three corners of the triangle in the diagram). Only two of the three are possible. A country that wants to fix the value of its currency and have an interest-rate policy that is free from outside influence (side C of the triangle) cannot allow capital to flow freely across its borders. If the exchange rate is fixed but the country is open to cross-border capital flows, it cannot have an independent monetary policy (side A). And if a country chooses free capital mobility and wants monetary autonomy, it has to allow its currency to float (side B). -
Anthony Scott Fonds
Anthony Scott fonds Compiled by Jane Turner (1990) Revised by Erwin Wodarczak (2014) and Stacy Paull (2016) University of British Columbia Archives Table of Contents Fonds Description o Title / Dates of Creation / Physical Description o Biographical Sketch o Scope and Content o Notes Series Descriptions o Correspondence series o Course Notes series o Lecture Notes series o Research Projects o UBC Administration series o Desk Diaries series o Miscellaneous Items series o Publications series File List Catalogue entry (UBC Library catalogue) Fonds Description Anthony Scott fonds. – 1942-2013. 8.65 m of textual materials. ca. 200 b&w photographs. 1 CD. Biographical Sketch Anthony Scott was born on August 2, 1923 in Vancouver. He received a Bachelor of Commerce in 1946, and a Bachelor of Arts in 1947, both from the University of British Columbia. He received a Master of Arts from Harvard University in 1949, and a Doctorate from the London School of Economics in 1953. The title of his dissertation was, "The Economics of Natural Resource Conservation." In 1953, Scott joined the Department of Economics at the University of British Columbia where he remained until his retirement in 1989. He attained the rank of full professor in 1961, and from 1967 to 1971, was chair of the department. Scott was also the recepient of several honours and awards. He is a Fellow of the Royal Society of Canada, received an Honourary Doctorate from the University of Guelph in 1980, and became an Officer of the Order of Canada in 1982. In 1987, he received the Innis-Gerin Medal. -
2. Anthraphane Monomer 23
Research Collection Doctoral Thesis Anthraphanes: a New Class of Potential Monomers for the Synthesis of Two-Dimensional Polymers Author(s): Servalli, Marco Publication Date: 2016 Permanent Link: https://doi.org/10.3929/ethz-a-010832536 Rights / License: In Copyright - Non-Commercial Use Permitted This page was generated automatically upon download from the ETH Zurich Research Collection. For more information please consult the Terms of use. ETH Library DISS. ETH NO. 23866 Anthraphanes: a New Class of Potential Monomers for the Synthesis of Two-Dimensional Polymers A thesis submitted to attain the degree of DOCTOR OF SCIENCES of ETH ZURICH (Dr. sc. ETH Zurich) presented by MARCO SERVALLI MSc, ETH Zurich Chemistry born on 10.07.1986 citizen of Bioggio (TI), Switzerland accepted on the recommendation of Prof. Dr. A. Dieter Schlüter, examiner Prof. Dr. Joost VandeVondele, co-examiner Prof. Dr. Peter Walde, co-examiner Dr. Michael Wörle, co-examiner 2016 ACKNOWLEDGEMENTS Acknowledgements Doing a PhD and writing a thesis is not a stand-alone matter and involves the collaboration of many people. I would like to start my acknowledgements from the scientific and work-related point of view: At first, I would like to thank Prof. A. Dieter Schlüter, for offering me the chance to work on the stimulating, fascinating and challenging topic of two-dimensional polymers. Challenging projects deal specially with a lot of frustration and I therefore appreciate the continuous support I received from him during my PhD, in terms of scientific and non-scientific discussion, as well as the essential ongoing motivation to not give up and to keep pursuing my objectives. -
Balance-Of-Payments Theory, and the International Monetary Problem
ESSAYS IN INTERNATIONAL FINANCE No. 124, November 1977 MONEY, BALANCE-OF-PAYMENTS THEORY, AND THE INTERNATIONAL MONETARY PROBLEM HARRY G. JOHNSON INTERNATIONAL FINANCE SECTION DEPARTMENT OF ECONOMICS PRINCETON UNIVERSITY Princeton, New Jersey This is the one hundred and twenty-fourth number in the series ESSAYS IN INTERNATIONAL FINANCE, published from time to time by the International Finance Section of the Department of Economics of Princeton University. This Essay is based upon the David Horowitz Lectures that Harry G. Johnson gave in Israel in 1975. Some weeks before his death on May 8, 1977, Professor Johnson wrote to ask whether the Section would like to publish a revised version of the Lectures. We do so now with a Foreword that was the obituary notice published by the Times of Lon- don; it was written by Professor W. M. Corden of the Australian National University. We are grateful to the Association of Banks in Israel for permission to publish the Horowitz Lectures, to Professor Corden, to the Times of London for permission to publish the obituary notice, to Elizabeth Johnson for reviewing the edited manuscript, and to Professor Jacob A. Frenkel for reading the proofs. The Section sponsors the essays in this series but takes no further responsibility for the opinions expressed in them. The writers are free to develop their topics as they wish. PETER B. KENEN, Director International Finance Section ESSAYS IN INTERNATIONAL FINANCE No. 124, November 1977 MONEY, BALANCE-OF-PAYMENTS THEORY, AND THE INTERNATIONAL MONETARY PROBLEM HARRY G. JOHNSON INTERNATIONAL FINANCE SECTION DEPARTMENT OF ECONOMICS PRINCETON UNIVERSITY Princeton, New Jersey Copyright © 1977, by International Finance Section Department of Economics, Princeton University Library of Congress Cataloging in Publication Data Johnson, Harry Gordon, 1923-1977. -
Douglas Views Effect of Automation by BRIAN MALCOLM “The First Prerequisite to Being an MP Is a Cast Iron Bottom.” So Said NDP Leader T
------ See You SieorgiQaiirD Invigilator Later SIR GEORGE WILLIAMS UNIVERSITY Volume XXVIII \ DECEMBER 8, 1964 No. 12 Discloses MIP's Deep-Seated Need Douglas Views Effect Of Automation By BRIAN MALCOLM “The first prerequisite to being an MP is a cast iron bottom.” So said NDP leader T. C. Douglas in an address to Johnson the Arts Faculty Association last Friday. In addition to cast iron posteriors, Mr. Douglas discussed automation and its effect on the economy. Outlines advocated solid bottoms A t Queen Elizabeth for the weary hours of endless parliamentary debate on such minor issues as Canada's new Lectures flag. When asked if he would By GIL BLOCK Xmas Bail support a motion of closure should Prime Minister Pearson At a Press Conference The University’s annual resort to this technique in ful held last Monday (Novem Christmas Ball will be held filling his promise of a “flag by ber 30) prior to his three day this year on Friday, Decem Christmas", Mr. Douglas said that lie would definitely not sup lecture series, Dr. Harry ber 11, at 9 p.m. port such a motion. Gordon Johnson, a leading “Due to the overwhelming suc economist, briefly outlined cess ot the Christm as Ball in “Closure.” he said, “is a pow past years, it has become both erful parliamentary weapon and each of the texts to be necessary and feasible for the should only be used for vital delivered. issues: we have been waiting 97 Students Undergraduate Society Dr. Johnson stated that each to obtain Galleries I, II, and III years for a flag, surely we can wait another 97 days ?” lecture would center upon a spe at the Queen Elizabeth Hotel,” cific institution, the theme for Mr. -
Johnson's Conversion from Keynesianism at Chicago
Johnson’s Conversion from Keynesianism at Chicago Russell S. Boyer* Department of Economics University of Western Ontario September 12, 2010 *The author would like to thank David Laidler for correspondence during the course of writing this paper, and Dave Burgess and Bob Solow for conversations about this topic. Comments from Dror Goldberg led to substantial revisions to a very preliminary first draft. Editing suggestions by Warren Young improved the exposition significantly. None of these individuals is responsible for the point of view expressed in this paper. 2 Abstract: “Johnson’s Conversion from Keynesianism at Chicago,” Russell S. Boyer, September 12, 2010 Johnson arrived at Chicago in 1959 identifying himself as a Keynesian, but during his period there he began to speak in derogatory terms about Keynes and about Keynesians. This paper analyzes the role that Friedman and Mundell played in this conversion. Our argument is that Johnson moved towards “the monetarist position,” but he denied that this was due to Friedman’s influence. Mundell’s thinking followed a similar path, both in his economics and in his assertion of independence from their distinguished colleague. The effect of these claims is to hide the fact that Friedman’s impact on their work was much greater than has generally been recognized. 3 1. Introduction Harry Johnson’s thinking concerning macroeconomic topics evolved markedly during the years 1959-1977, while he was at the University of Chicago. His move from Keynesianism towards “the monetarist position”1 over this period has been noted by numerous observers, including such well-known economists as Bhagwati (1977) and Polak (2002). -
201120 111111
Instituto de Física de São Carlos Universidade de São Paulo Departamento de Física e Ciência dos Materiais RELATÓRIO DE ATIVIDADES 2020201120 111111 CChheeffee::: PPPPPPrrrrrrrrrooooooffffff......... DDDDDDrrrrrrr......... LLLLLLuuuuuuiiiiiiiiizzzzzz AAAAAAggggggoooooossssssttttttiiiiiiiiinnnnnnhhhhhhoooooo FFFFFFeeeeeerrrrrrrrrrrrrrrrrreeeeeeiiiiiiiiirrrrrrrrraaaaaa SSuupplleennttee::: PPPPPPrrrrrrrooooooffffff......... DDDDDDrrrrrrr......... LLLLLLuuuuuuiiiiiiiiissssss GGGGGGuuuuuussssssttttttaaaaaavvvvvvoooooo MMMMMMaaaaaarrrrrrrccccccaaaaaassssssssssssaaaaaa Ficha catalográfica elaborada pelo Serviço de Biblioteca e Informação Universidade de São Paulo. Instituto de Física de São Carlos. Relatório de atividades do ano de 2011 do Departamento de Física e Ciências dos Materiais/IFSC/USP./Organizado por Isabel Rosani Constantino...[ et al]. São Carlos: Departamento de Física e Ciência dos Materiais, 2012. 320p. 1.Relatório de atividades. I. Constantino, Isabel Rosani. II. Cagnin, Cristiane A. III. Lopes, Yvone A. B. IV. Monzane, Thaís Fernanda G. S. V. Oliveira, Rosangela M. M. VI. Pereira, Daniel F. VII. Reis, Simone F. VIII. Sertori, Isabel C. De Vitro. IX. Signini, Érica R. F. X.Título. INTRODUÇÃO a) Perfiill do Departamento de Físiica e Ciiênciia dos Materiiaiis ii b) Atiiviidades de Ensiino iiv c) Produção Técniico-Ciientífiica v d) Orientações e Teses Defendiidas iix e) Atiiviidades de Extensão xiiii f) Recursos Fiinanceiiros Obtiidos xiiii g) Resumo Quantiitatiivo da Produção Ciientífiica xv h) Atiiviidades de Ensiino e Pesquiisa -
Richard Stone: an Annotated Bibliography
Mauro Baranzini GianDemetrio Marangoni Richard Stone: an Annotated Bibliography Mauro Baranzini GianDemetrio Marangoni University of Lugano and University of Verona and Accademia dei Lincei - Rome University of Lugano Richard Stone: an Annotated Bibliography USI First edition: 2015 ISBN 978-88-6101-014-7 Copyright © 2014 Università della Svizzera italiana CH-6900 Lugano The ‘Stone Collection’ at the Central Library of the University of Lugano comprises Richard Stone’s complete works in the field of economics. The collection consists of approximately 200 articles and books, published between 1936 and 1991, the year of his death, as well as some posthumous works, manuscripts and secondary literature. Much of the material comes from a donation by Richard Stone’s wife, Giovanna. The remaining part has been assembled and made available by the authors of this bibliography and by the Library of the University of Lugano (BUL). This Annotated Bibliography is also part of the Collection. It presents brief comments on each item in the collection, biographical notes and some more general considerations. The authors would like to thank Domenico Rossignoli for bibliographical research and Nigel and Caroline Webb for text revision. Particular thanks are due to the Director of the University Library, Giuseppe Origgi, for his valuable collaboration with this project. 1 The task of presenting the contributions of Richard Stone to economics, and in particular to the theory of income distribution, is facilitated, to some extent, by the existence of a number of complete lists of his publications, issued in books and international journals [see, for instance, Bibliography of Richard Stone’s Works, 1936-1984, The Scandinavian Journal of Economics , Vol. -
Harry Gordon Johnson 1923-1977 (The One and Only Harry, 2004)
THE ONE AND ONLY HARRY To be published in the New Dictionary of National Biography, Oxford: Oxford University Press, about 2004 Harry Gordon Johnson (l923-l977) JOHNSON, HARRY GORDON (1923-1977), economist, was born 26 May 1923 in Toronto, Canada, the elder son of Henry Herbert Johnson, newspaperman and later secretary of the Liberal Party of Ontario, and his wife Frances Lily Muat, lecturer in Child Psychology at the Institute of Child Study of the University of Toronto. There were two children, both sons. He was educated at the University of Toronto schools and then obtained scholarships to the University of Toronto. After considering law, favored by his father, he entered the Honours course in Political Science and Economics. He developed an interest in the history of thought and was much influenced by Harold Innes' lectures and ideas on Canadian and general economic history. He later wrote that they remained an integral part of his intellectual equipment ever since. He graduated in l943 and then, at age 2l, became, for one year, acting professor and sole member of the economics staff at St. Francis Xavier University in Antigonish, Nova Scotia. In l944, he volunteered for active service in the Canadian armed forces and, after training, was sent to England in l945, eventually doing clerical work in Canada House. Being demobilized in Britain, he was sent by the army to Cambridge, 1 became an affiliated student of Jesus College, and took another bachelor's degree, obtaining the top first class in the economics tripos. Maurice Dobb was his supervisor. He became a member of the Political Economy Club, and at his first meeting heard J.M.