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Emtree Updates

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Emtree Updates Emtree Terms Changed in May 2019 1 Emtree Terms Added and Changed (May 2019) This is an overview of new terms added and changes made in the second Emtree release in 2019. Overall, Emtree has grown by 526 preferred terms (155 drug terms and 371 non-drug terms) compared with the previous version released in January 2019. In total Emtree now counts 82970 preferred terms. Because the terms added include replacements for existing preferred terms (which become synonyms of the new terms) as well as completely new concepts, the number of terms added exceeds the net growth in Emtree. Other changes could include the merging of two or more existing preferred terms into a single concept. The terms added and changed are summarized below and specified in detail on the following pages. Emtree Terms Added in May 2019 567 new terms (including 41 replacement terms and promoted synonyms) have been added to Emtree as preferred terms in version May 2019 (compared to January 2019): ◼ 176 drug terms (terms assigned to the Chemicals and Drugs facet). ◼ 391 non-drug terms (terms not assigned as Chemicals and Drugs). The new terms (including the replacement terms and the promoted synonyms) are listed as Terms Added on the following pages. Note that many of these terms will have been indexed prior to 2019 (typically as candidate terms), sometimes for several years, before they were added to Emtree. Emtree Terms Changed in May 2019 41 terms (21 drug terms and 20 non-drug terms) from Emtree January 2019 have been replaced by 39 different terms in May 2019 (21 drug terms and 18 non-drug terms). Of these, 32 terms (16 drug terms and 16 non-drug terms) are new (e.g. new generic names for drug chemical names) and have been assigned creation date 2019; the remaining 7 replacement terms (5 drug terms and 2 non-drug terms) were already present in Emtree. No drug terms were replaced by a non-drug term, no non-drug term were replaced by a drug term. No preferred terms were deleted. Changes are presented in alphabetical order of the new terms. Emtree Terms Added in May 2019 2 Drug terms ABC-type alpha-factor-pheromone transporter dersimelagon ABC-type beta-glucan transporter deruxtecan ABC-type capsular-polysaccharide transporter diclofenac plus paracetamol ABC-type Cd2+ transporter dilpacimab ABC-type dipeptide transporter dm1 (drug) ABC-type fatty-acyl-CoA transporter dm4 ABC-type Fe3+ transporter dostarlimab ABC-type ferric citrate transporter duocarmazine ABC-type ferric enterobactin transporter durlobactam ABC-type ferric hydroxamate transporter eftozanermin alfa ABC-type glycerol 3-phosphate transporter eladocagene exuparvovec ABC-type guanine transporter eluforsen ABC-type heme transporter emtansine ABC-type lipid A-core oligosaccharide transporter encequidar ABC-type lipopolysaccharide transporter ensifentrine ABC-type maltose transporter epinephrine plus mepivacaine ABC-type Mn2+ transporter etokimab ABC-type molybdate transporter exicorilant ABC-type Na+ transporter ferredoxin-NAD+ oxidoreductase (Na+- ABC-type Ni2+ transporter transporting) ABC-type nitrate transporter fosgemcitabine palabenamide ABC-type nonpolar-amino-acid transporter fosifloxuridine nafalbenamide ABC-type oligopeptide transporter foslinanib ABC-type oligosaccharide transporter fosmanogepix ABC-type phosphate transporter futibatinib ABC-type phosphonate transporter galicaftor ABC-type polar-amino-acid transporter gallium 68 plus germanium 68 ABC-type polyamine transporter garetosmab ABC-type protein transporter gentamicin plus hydrocortisone aceponate plus ABC-type quaternary amine transporter miconazole ABC-type sulfate transporter gleptoferron plus toltrazuril ABC-type taurine transporter golexanolone ABC-type teichoic-acid transporter gremubamab ABC-type tungstate transporter H+-exporting diphosphatase ABC-type vitamin B12 transporter hexapneumine anetumab hyaluronidase plus trastuzumab apamistamab i 131 iadademstat ascorbate ferrireductase (transmembrane) idecabtagene vicleucel atoltivimab ilginatinib avexitide indatuximab avian infectious bronchitis virus vaccine lenzumestrocel barzuxetan leriglitazone bermekimab lorvotuzumab betamethasone acetate plus florfenicol plus maftivimab terbinafine masupirdine biclotymol maytansine derivative biotin-dependent malonate decarboxylase menaquinol oxidase (H+-transporting) branebrutinib mertansine caldariellaquinol oxidase (H+-transporting) miricorilant cantuzumab mitochondrial protein-transporting ATPase carboxybiotin decarboxylase mivavotinib chloroplast protein-transporting ATPase murlentamab cobolimab Na+-transporting two-sector ATPase coccidiosis vaccine NADH:ubiquinone reductase (Na+-transporting) coltuximab nanatinostat danicopan neluxicapone Emtree Terms Added in May 2019 3 nerinetide rolinsatamab nimacimab rolinsatamab talirine obexelimab rovafovir etalafenamide odevixibat ruxotemitide olenasufligene relduparvovec samotolisib olinvacimab selatogrel omega interferon seprehvir ontamalimab serdexmethylphenidate orilanolimab setamevetcel osocimab setogepram oxaloacetate decarboxylase (Na+ extruding) sintilimab oxymetazoline plus tetracaine siremadlin P-type Ag+ transporter soticlestat P-type Cu+ transporter spesolimab P-type Cu2+ transporter tabituximab P-type K+ transporter tabituximab barzuxetan P-type Mg2+ transporter tafasitamab P-type Na+ transporter taniborbactam P-type phospholipid transporter telaglenastat P-type Zn2+ transporter temelimab pegbelfermin teserpaturev porcine atrophic rhinitis vaccine tildacerfont porcine circovirus porcine enzootic pneumonia tirbanibulin vaccine toripalimab porcine parvovirosis vaccine translocase pozelimab ubiquinol oxidase (electrogenic, proton-motive prademagene zamikeracel force generating) prolgolimab ubiquinol oxidase (H+-transporting) protein-secreting ATPase umibecestat proton-translocating NAD(P)+ transhydrogenase vafidemstat ravtansine valecobulin repotrectinib vofatamab resamirigene bilparvovec volrubigene ralaparvovec resmetirom zampilimab rocacetrapib Emtree Terms Added in May 2019 4 Non-drug terms brushite stone bulbar conjunctiva calcaneonavicular coalition calcium carbonate urolithiasis A Measurement Tool to Assess Systematic Reviews calcium oxalate dihydrate stone abdominal aortic wall calcium oxalate monohydrate stone Acarapis calcium oxalate urolithiasis Aceria calcium phosphate urolithiasis adactylia calcium stone (cholelithiasis) adult neuronal ceroid lipofuscinosis calcium stone (urolithiasis) Alocasia macrorrhizos canalolithiasis alveolar crest cancer free survival amebic keratitis Candida haemulonis amnesic shellfish poisoning cardiovascular calcification Amorphophallus konjac Caretta Amorphophallus paeoniifolius carotid artery calcification Amorphophallus paeoniifolius var. campanulatus carpal coalition amputation free survival caudal ventrolateral medulla anhydramnios CC50 (cytotoxic concentration) animal parameters CD50 (cytotoxic dose) anterior vena cava cerebral ischemia reperfusion injury aorta stripping cerebrospinal fluid-to-serum ratio aortic arch aneurysm Chelonia aortic calcification chemical fingerprinting aortic root calcification Cheyletiella aortic valve calcification choline deficiency apatite stone chromium deficiency Arbutus chronic pulmonary aspergillosis Arbutus unedo Clinacanthus arginine deficiency Clinacanthus nutans Arum maculatum Codex Alimentarius Arum palaestinum comet parameters ascending aortic aneurysm concanavalin A-induced liver injury Australopithecus conformity (social behavior) avoidant restrictive food intake disorder congenital amputation B-3 cell line (lens epithelium) congenital hereditary endothelial dystrophy B12 deficiency coprolite bacteriotherapy cupulolithiasis band keratopathy cutting stapler behavioral test parameters cystine stone benzo[a]pyrene-resistant cell line cytotoxic dose Bietti crystalline dystrophy dacryolithiasis bioabsorbable mesh data accuracy biochemical disease free survival data completeness biochemical progression free survival data consistency biotin deficiency data paper bladder contractility index data quality bladder intercontraction interval data quality assessment bladder outlet obstruction index data validity bladder strip Demodex brevis Blighia sapida descending aortic aneurysm bone hydatidosis diabetic eye disease bone surface density diabetic keratopathy bone volume diabetic ophthalmoplegia bone volume fraction diarrhetic shellfish poisoning brain echinococcosis disability free survival brain-to-serum ratio distant disease free survival breast tomosynthesis system distant progression free survival bromine poisoning distant recurrence free survival broncholithiasis dolichostenomelia Emtree Terms Added in May 2019 5 dose volume histogram Homo denisovan Dracocephalum Homo erectus Dracocephalum kotschyi Homo heidelbergensis Dracocephalum moldavica hot yoga emotional eating humeral component of shoulder prosthesis end-diastolic pressure-volume relationship humeral cup end-systolic pressure-volume relationship humeral stem endothelium-intact aortic ring humeroradial synostosis enterolithiasis hypocupremia EO771 cell line hypoferremia epithelial basement membrane dystrophy hypophalangia erectile tissue (penis) infantile neuronal ceroid lipofuscinosis Eretmochelys infrarenal aortic aneurysm Eriophyidae inner retina experimental Chagas disease internal limiting membrane experimental protozoal infection International Federation of Red Cross and Red experimental Staphylococcus aureus infection Crescent Societies experimental Staphylococcus infection intestinal stasis external limiting membrane intoeing
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