Supplementary Table 1 - Odorant Panels Used in Various Experiments

Total Page:16

File Type:pdf, Size:1020Kb

Supplementary Table 1 - Odorant Panels Used in Various Experiments SUPPLEMENTARY TABLE 1 - ODORANT PANELS USED IN VARIOUS EXPERIMENTS 1 (A). INITIAL SCREEN (25 odorants) (-)-carvone 2-pentyl furan benzaldehyde isoeugenol 1,4-cineole 4-allyl anisole citral limonene 1-methyl pyrrole allyl sulfide eucalyptol methyl salicylate 1-octen-3-ol alpha-ionone gamma-heptalactone propionaldehyde 2,3-butanedione alpha-pinene guaiacol trans-3-hexenoic acid 2-ethyl phenol amyl acetate isobutyric acid trans-cinnamaldehyde 2-methyl pyrazine 1 (B). MIXTURE SCREEN (348 odorants, 58 mixtures of 6) hexyl acetate propyl propionate ethyl caprate isoeugenol 6-methylquinoline geraniol 1-nonanol tetrahydrofurfuryl alcohol isobutyraldehyde alpha-pinene ethyl acrylate phenyl actetate 2-methyl-1-propane thiol 1-methyl pyrrole alpha amyl cinnamaldehyde 3-acetyl-2,5-dimethyl furan 4-methyl anisole methyl myristate decanol bacdanol nonanal 2-methyl butyraldehyde trans-3-hexen-1-ol floralozone pyridine 2-tert-butyl cyclohexanone 1,4-butane dithiol veratrole ethyl heptanoate (+)-rose oxide 2-methyl pyrazine (+/-)-4-heptanolide pelargonic acid heptyl isobutyrate (-)-2-butanol acetophenone cis-3-hexen-1-ol ethyl acetate 3-methylcyclopentanone p-anisaldehyde 3-heptanone eucalyptol pentyl propionate 2-acetyl thiazole isoamyl amine 3-decanone bis-(methylthio) methane 2-phenyl ethanol valeraldehyde 2,5-dimethyl pyrazine 2-methyl anisole styralyl propionate phenetole (+/-)-citronellal 2-methoxy pyrazine ethyl ortho methoxy benzoate alpha-amyl cinnamaldehyde dimethyl acetal 2-nonanone acetaldehyde 2-propenyl phenol 1,3-butane dithiol diethyl sebacate 1-mercapto-2-propanol ethyl palmitate methyl laurate cyclohexanol piperidine myrcene geranyl acetone (-)-isopulegol 2-methyl-2-hexanol gamma-heptalactone dihydrocoumarin propionic acid benzyl mercaptan damascenone (-)-carvone isobutyl isobutyrate 5-methyl-3-heptanone orange terpene isovaleric acid 1-heptaldehyde ethyl caprylate acetyl acetone 2-nonanol 1-butanol triethyl citrate 1-propanethiol 2-acetyl-5-methyl furan 1,4-cineole allyl benzene octane ethyl propionate 3-hexanol methyl salicylate diethyl amine 1,3-propane dithiol thiazole ethyl formate andrane butyl acetate propionaldehyde methyl disulfide lyrame valeric acid amyl butyrate allyl butyrate methyl-2-octynoate 2,6-lutidine eugenol (-)-beta-citronellol ethyl benzoylacetate pyrrole ethyl salicylate 2,3-diethyl-5-methyl pyrazine gamma-caprolactone 4-heptanone 2-propanol cis-3-hexenyl formate dihydrojasmonate p-cymene toluene dicyclohexyl disulfide tobacarol benzyl alcohol alpha-ionone allyl phenyl acetate kohinool methyl dihydrojasmonate 3-ethyl phenol cis-4-hepten-1-al cinnamyl nitrile (+)-fenchone 2-acetyl thiophene (-)-2-octanol 6-amyl-alpha-pyrone (-)-rose oxide butyl butyrate linalyl isovalerate alpha-bisabolol 2-cyclohexen-1-one isobutyric acid ethyl nonanoate linalool oxide methyl butyrate dimethyl trisulfide methyl caproate maritima phenethyl amine citral thiophenol grisalva laurinaldehyde 3-octanol benzaldehyde alpha-phellandrene 2-ethyl phenol benzene trans-2-hexen-1-ol maple furanone linalool 2,3-hexanedione 4-carvomenthenol citronellyl acetate 2-butanone ethyl caproate (+)-pulegone trans-2-decenal allyl sulfide octyl isobutyrate 2-phenethyl acetate vigoflor 2-methyl valeric acid allyl disulfide methyl valerate verdural extra 3-octanone 2-octanone allyl acetic acid gamma-dodecalactone methyl acetate alpha-terpinene 6-methyl-5-hepten-2-one 2-n-butyl furan isovaleraldehyde pyrrolidine 1-hexane thiol mesityl oxide 1,3-dimethoxybenzene carvacryl ethyl ether 2,3-diethyl pyrazine nerol butyl amine farnesene octanal diethyl pyrocarbonate cyclohexanecarboxylic acid diacetyl 1-phenyl ethanol trans-3-hexenoic acid propyl acetate 1-pentanol methyl enanthate 3-methylthio propionaldehyde cis-nerolidol ethyl benzoate 2-methyl-3-hexanone 1-hexyne quinoline cyclohexanone trans-cinnamaldehyde 1-methyl piperidine 1-hexanol isophorone 2-ethyl-5-methyl furan 2-acetoxy-3-butanone trans-2-hexen-1-al beta-ionone carvacrol nonane isobutyl amine 1,2-ethane dithiol L-turpentine 2,4,5-trimethyl thiazole butyl propionate butyraldehyde 3-pentanone (+)-2-heptanol 2-propen-1-thiol ethyl butyrate 3-ethyl pyridine triethylamine 2-decanol 1-propanol tert-butyl propionate methacrolein (-)-verbenone 2-methoxy-3-methyl pyrazine 3-mercapto-1-propanol 3-penten-2-one (-)-fenchone 1-acetonaphthone crotonaldehyde proflora anethole 1-octen-3-ol 3-methyl-2-pentanone dimethyl cyclormol (-)-carveol (L-carveol) 2-sec-butyl cyclohexanone cyclopentanethiol delta-octanolactone 2-methyl valeraldehyde geranyl acetate isoamyl formate perillaldehyde methyl decanoate 3-pentanol caproic acid propiophenone 1-furfuryl pyrrole 3-acetyl-2,5-dimethyl thiophene trans-2-pentenal 2-pentyl furan pentyl acetate 1-heptanol allyl cinnamate 1-methyl naphthalene (+/-)-2-hexanol (+)-carvone 2-methoxy-4-methyl phenol 5-methyl-2-thiophene carboxaldehyde cuminaldehyde octyl acetate (-)-menthone menthyl acetate butyric acid furfuryl mercaptan (+)-limonene cis-jasmone 2,3,10-mercaptopinane thioglycolic acid trans,trans-2-heptadienal cashmeran quinaldine trans-2-nonen-1-al caprylic acid mesitylene oenanthic acid 4-penten-1-ol (-)-myrtenal isomenthone 2-hexanone ethyl valerate 2-methyl-2-pentanol (-)-thujone guaiacol (+)-2-butanol heptyl butyrate ethyl tiglate 4-allyl anisole 4-octanone (-)-5-hydroxy-2-hexanone safrole 3-methyl butanol decanal safranal cyclooctane propyl butyrate S-methyl thiobutanoate (+)-alpha-methylbenzyl amine valencene 2-hydroxyacetophenone allyl phenoxyacetate o-tolyl isobutyrate pentane benzyl acetate styrene 2,2'-dithiodimethylenedifuran gamma-terpinene tributyrin butyl butyryllactate beta-damascone d-piperitone 2-pentanone (+/-)-theaspirane m-cresol m-xylene 3-heptanol ethyl pyruvate S-(+)-phenylbutyric acid 1,4-thioxane butyl methyl ether benzyl salicylate butyl formate 2-octenal (-)-trans-caryophyllene methyl eugenol 1-octanol dibenzyl ether methyl propionate 3-nonanone 5-methyl-2-hexanone tetrahydrofurfuryl acetate (+/-)-2-pentanol 3,7-dimethyl-2,6-octadienenitrile anisole 2-ethyl fenchol 1 (C). AWAKE ANIMAL SCREEN (100 odorants, 25 mixtures of 4) octanal fenchone (-) 2-methyl-3,5-dimethylpyrazine 2-methyl quinoline methyl salicylate 2-methoxypyrazine 3-methylcyclopentanol pyrrolidine isopulegol (-) diethyl amine 1,4-cineole cyclohexanone carvone (-) gamma-terpinene 2-phenethyl acetate citronellal (+/-) isobutyric acid 3-(methylthio)propionaldehyde 1-octen-3-ol 4-allyl anisole rose oxide (-) 1,4-thioxane 3-heptanone 2-nonanone hexanol 2-pentyl furan methyl laurate allyl sulfide isophorone valencene cuminaldehyde 1-butanol maritima menthone (-) 2-methyl pyrazine kohinool p-cymene pentane menthyl acetate cyclooctane p-anisaldehyde myrcene 1-hexene limonene (R) (+) grisalva amyl acetate phenetole 5-methyl-2-thiophenecarboxaldehyde mesitylene cashmeran 2,6-lutidine cis-jasmone 1-hexyne isovaleraldehyde butyric acid valeraldehyde alpha-phellandrene 1-methyl pyrrole heptaldehyde eucalyptol ethyl vinyl ketone carvacrol linalool ethyl propionate 1-methylnaphthalene citral isobutyl isobutyrate 1-octanol valeric acid 2-acetylthiazole propionaldehyde alpha-pinene safrole octyl acetate anethole trans-2-cis-6-nonadienal thujone (-) 2-decanol 2-pentanol (+/-) trans-3-hexenoic acid trans-cinnamaldehyde 2-ethyl phenol geraniol benzene guaiacol methyl-2-octynoate alpha-ionone butyl butyrate 3,7-dimethyl-2,6-octadienenitrile 2-butanone veratrole 2,3-butanedione tobacarol methyl disulfide benzaldehyde floralozone gamma-heptalactone cis-nerolidol farnesene isoeugenol.
Recommended publications
  • Retention Indices for Frequently Reported Compounds of Plant Essential Oils
    Retention Indices for Frequently Reported Compounds of Plant Essential Oils V. I. Babushok,a) P. J. Linstrom, and I. G. Zenkevichb) National Institute of Standards and Technology, Gaithersburg, Maryland 20899, USA (Received 1 August 2011; accepted 27 September 2011; published online 29 November 2011) Gas chromatographic retention indices were evaluated for 505 frequently reported plant essential oil components using a large retention index database. Retention data are presented for three types of commonly used stationary phases: dimethyl silicone (nonpolar), dimethyl sili- cone with 5% phenyl groups (slightly polar), and polyethylene glycol (polar) stationary phases. The evaluations are based on the treatment of multiple measurements with the number of data records ranging from about 5 to 800 per compound. Data analysis was limited to temperature programmed conditions. The data reported include the average and median values of retention index with standard deviations and confidence intervals. VC 2011 by the U.S. Secretary of Commerce on behalf of the United States. All rights reserved. [doi:10.1063/1.3653552] Key words: essential oils; gas chromatography; Kova´ts indices; linear indices; retention indices; identification; flavor; olfaction. CONTENTS 1. Introduction The practical applications of plant essential oils are very 1. Introduction................................ 1 diverse. They are used for the production of food, drugs, per- fumes, aromatherapy, and many other applications.1–4 The 2. Retention Indices ........................... 2 need for identification of essential oil components ranges 3. Retention Data Presentation and Discussion . 2 from product quality control to basic research. The identifi- 4. Summary.................................. 45 cation of unknown compounds remains a complex problem, in spite of great progress made in analytical techniques over 5.
    [Show full text]
  • Sassafras Tea: Using a Traditional Method of Preparation to Reduce the Carcinogenic Compound Safrole Kate Cummings Clemson University, [email protected]
    Clemson University TigerPrints All Theses Theses 5-2012 Sassafras Tea: Using a Traditional Method of Preparation to Reduce the Carcinogenic Compound Safrole Kate Cummings Clemson University, [email protected] Follow this and additional works at: https://tigerprints.clemson.edu/all_theses Part of the Forest Sciences Commons Recommended Citation Cummings, Kate, "Sassafras Tea: Using a Traditional Method of Preparation to Reduce the Carcinogenic Compound Safrole" (2012). All Theses. 1345. https://tigerprints.clemson.edu/all_theses/1345 This Thesis is brought to you for free and open access by the Theses at TigerPrints. It has been accepted for inclusion in All Theses by an authorized administrator of TigerPrints. For more information, please contact [email protected]. SASSAFRAS TEA: USING A TRADITIONAL METHOD OF PREPARATION TO REDUCE THE CARCINOGENIC COMPOUND SAFROLE A Thesis Presented to the Graduate School of Clemson University In Partial Fulfillment of the Requirements for the Degree Master of Science Forest Resources by Kate Cummings May 2012 Accepted by: Patricia Layton, Ph.D., Committee Chair Karen C. Hall, Ph.D Feng Chen, Ph. D. Christina Wells, Ph. D. ABSTRACT The purpose of this research is to quantify the carcinogenic compound safrole in the traditional preparation method of making sassafras tea from the root of Sassafras albidum. The traditional method investigated was typical of preparation by members of the Eastern Band of Cherokee Indians and other Appalachian peoples. Sassafras is a tree common to the eastern coast of the United States, especially in the mountainous regions. Historically and continuing until today, roots of the tree are used to prepare fragrant teas and syrups.
    [Show full text]
  • Precursors and Chemicals Frequently Used in the Illicit Manufacture of Narcotic Drugs and Psychotropic Substances 2017
    INTERNATIONAL NARCOTICS CONTROL BOARD Precursors and chemicals frequently used in the illicit manufacture of narcotic drugs and psychotropic substances 2017 EMBARGO Observe release date: Not to be published or broadcast before Thursday, 1 March 2018, at 1100 hours (CET) UNITED NATIONS CAUTION Reports published by the International Narcotics Control Board in 2017 The Report of the International Narcotics Control Board for 2017 (E/INCB/2017/1) is supplemented by the following reports: Narcotic Drugs: Estimated World Requirements for 2018—Statistics for 2016 (E/INCB/2017/2) Psychotropic Substances: Statistics for 2016—Assessments of Annual Medical and Scientific Requirements for Substances in Schedules II, III and IV of the Convention on Psychotropic Substances of 1971 (E/INCB/2017/3) Precursors and Chemicals Frequently Used in the Illicit Manufacture of Narcotic Drugs and Psychotropic Substances: Report of the International Narcotics Control Board for 2017 on the Implementation of Article 12 of the United Nations Convention against Illicit Traffic in Narcotic Drugs and Psychotropic Substances of 1988 (E/INCB/2017/4) The updated lists of substances under international control, comprising narcotic drugs, psychotropic substances and substances frequently used in the illicit manufacture of narcotic drugs and psychotropic substances, are contained in the latest editions of the annexes to the statistical forms (“Yellow List”, “Green List” and “Red List”), which are also issued by the Board. Contacting the International Narcotics Control Board The secretariat of the Board may be reached at the following address: Vienna International Centre Room E-1339 P.O. Box 500 1400 Vienna Austria In addition, the following may be used to contact the secretariat: Telephone: (+43-1) 26060 Fax: (+43-1) 26060-5867 or 26060-5868 Email: [email protected] The text of the present report is also available on the website of the Board (www.incb.org).
    [Show full text]
  • Electrophysiological and Behavioral Characterization Of
    Deletre et al. Parasites & Vectors (2015) 8:316 DOI 10.1186/s13071-015-0934-y RESEARCH Open Access Electrophysiological and behavioral characterization of bioactive compounds of the Thymus vulgaris, Cymbopogon winterianus, Cuminum cyminum and Cinnamomum zeylanicum essential oils against Anopheles gambiae and prospects for their use as bednet treatments Emilie Deletre1* , Fabrice Chandre2, Livy Williams3, Claire Duménil1, Chantal Menut4 and Thibaud Martin1,5 Abstract Background: Laboratory and field studies showed that repellent, irritant and toxic actions of common public health insecticides reduce human-vector contact and thereby interrupt disease transmission. One of the more effective strategies to reduce disease risk involves the use of long-lasting treated bednets. However, development of insecticide resistance in mosquito populations makes it imperative to find alternatives to these insecticides. Our previous study identified four essential oils as alternatives to pyrethroids: Thymus vulgaris, Cymbopogon winterianus, Cuminum cyminum, Cinnamomum zeylanicum. The objectives of this study were to identify active compounds of these essential oils, to characterize their biological activity, and to examine their potential as a treatment for bednets. Methods: We evaluated the electrophysiological, behavioural (repellency, irritancy) and toxic effects of the major compounds of these oils against Anopheles gambiae strain ‘Kisumu’. Results: Aldehydes elicited the strongest responses and monoterpenes the weakest responses in electroantennogram (EAG) trials. However, EAG responses did not correlate consistently with results of behavioral assays. In behavioral and toxicity studies, several of the single compounds did exhibit repellency, irritancy or toxicity in An. gambiae; however, the activity of essential oils did not always correlate with activity expected from the major components. On the contrary, the biological activity of essential oils appeared complex, suggesting interactions between individual compounds and the insect under study.
    [Show full text]
  • Aldrich Vapor
    Aldrich Vapor Library Listing – 6,611 spectra This library is an ideal tool for investigator using FT-IR to analyze gas phase materials. It contains gas phase spectra collected by Aldrich using a GC-IR interface to ensure chromatographically pure samples. The Aldrich FT-IR Vapor Phase Library contains 6,611 gas phase FT-IR spectra collected by Aldrich Chemical Company using a GC interface. The library includes compound name, molecular formula, CAS (Chemical Abstract Service) registry number, Aldrich catalog number, and page number in the Aldrich Library of FT-IR Spectra, Edition 1, Volume 3, Vapor-Phase. Aldrich Vapor Index Compound Name Index Compound Name 6417 ((1- 3495 (1,2-Dibromoethyl)benzene; Styrene Ethoxycyclopropyl)oxy)trimethylsilane dibromide 2081 (+)-3-(Heptafluorobutyryl)camphor 3494 (1-Bromoethyl)benzene; 1-Phenylethyl 2080 (+)-3-(Trifluoroacetyl)camphor bromide 262 (+)-Camphene; 2,2-Dimethyl-3- 6410 (1-Hydroxyallyl)trimethylsilane methylenebicyclo[2.2.1]heptane 6605 (1-Methyl-2,4-cyclopentadien-1- 2828 (+)-Diisopropyl L-tartrate yl)manganese tricarbonyl 947 (+)-Isomenthol; [1S-(1a,2b,5b)]-2- 6250 (1-Propynyl)benzene; 1-Phenylpropyne Isopropyl-5-methylcyclohexano 2079 (1R)-(+)-3-Bromocamphor, endo- 1230 (+)-Limonene oxide, cis + trans; (+)-1,2- 2077 (1R)-(+)-Camphor; (1R)-(+)-1,7,7- Epoxy-4-isopropenyl-1- Trimethylbicyclo[2.2.1]heptan- 317 (+)-Longifolene; (1S)-8-Methylene- 976 (1R)-(+)-Fenchyl alcohol, endo- 3,3,7-trimethyltricyclo[5.4.0 2074 (1R)-(+)-Nopinone; (1R)-(+)-6,6- 949 (+)-Menthol; [1S-(1a,2b,5a)]-(+)-2- Dimethylbicyclo[3.1.1]heptan-2-
    [Show full text]
  • Pdf 462.69 K
    Journal of Oil, Gas and Petrochemical Technology Vol. 5, No. 1 , pp. 63 - 75 6 3 The Investigation of Purity Improvement for the Production of Methyl Propionate in Different Types of Batch Distillation Systems Dhia Y. Aqar * 1 , Hassan H. Al Alak 2 , N. Rahmanian 3 , I.M. Mujtaba 3 1 Ministry of Oil, South Refineries Company, Basra, Iraq 2 Department of Materials Engineering, Faculty of Engineering, University of Kufa, Najaf, Iraq 3 Faculty of Engineering and Informatics, University of Bradford, Bradford, UK ARTICLE INFO ABSTRACT Received: January 06, 2018 Methyl propionate, also known as methyl propanoate, Accepted: September 08, 2018 is a clear colourless liquid with a characteristic odour (fruity smel l and taste). In this study , the formation of methyl propionate through the esterification o Keywords : propionic acid and methanol was inves tigated in the Methyl propionate reactive distillation system using a conventional (CBD), CBD single feed (SF - SBD), and double feed semi - batch SF - SBD distillatio n (DF - SBD) columns for the first time . The Double feed semi - batch distillation performances measure o f these distillation systems (DF - SBD) were evaluated in terms of min imum batch time for a given separation task. The optimization results clearly * Corresponding author: show ed that the DF - SBD system is a more attractive E - mail: : [email protected] operation in terms of reaction conversion, and maximum achievable purity as compared to the SF SBD, and CBD processes. 64 Dhia Y. Aqar et al. 1. Introduction Methyl propionate is a very important component which has useful applications in a variety of areas in the chemical industry such as solvents for cellulose nitrate, lacquers, plasticizers, chemical intermediates, fragrances, flavors, a raw material in organic synthesis for the production of varnishes, paints, and other chemical compound s such as methyl methacrylate [1] .
    [Show full text]
  • Experimental and Modeling Study of the Thermal Decomposition of Methyl Decanoate Olivier Herbinet, Pierre Alexandre Glaude, Valérie Warth, Frédérique Battin-Leclerc
    Experimental and modeling study of the thermal decomposition of methyl decanoate Olivier Herbinet, Pierre Alexandre Glaude, Valérie Warth, Frédérique Battin-Leclerc To cite this version: Olivier Herbinet, Pierre Alexandre Glaude, Valérie Warth, Frédérique Battin-Leclerc. Experimental and modeling study of the thermal decomposition of methyl decanoate. Combustion and Flame, Elsevier, 2011, 158 (7), pp.1288-1300. 10.1016/j.combustflame.2010.11.009. hal-00724939 HAL Id: hal-00724939 https://hal.archives-ouvertes.fr/hal-00724939 Submitted on 23 Aug 2012 HAL is a multi-disciplinary open access L’archive ouverte pluridisciplinaire HAL, est archive for the deposit and dissemination of sci- destinée au dépôt et à la diffusion de documents entific research documents, whether they are pub- scientifiques de niveau recherche, publiés ou non, lished or not. The documents may come from émanant des établissements d’enseignement et de teaching and research institutions in France or recherche français ou étrangers, des laboratoires abroad, or from public or private research centers. publics ou privés. Experimental and modeling study of the thermal decomposition of methyl decanoate Olivier Herbineta,*, Pierre-Alexandre Glaudea, Valérie Wartha and Frédérique Battin-Leclerca a Laboratoire Réactions et Génie des Procédés, Nancy Université, CNRS UPR 3349, BP 20451, 1 rue Grandville, 54001 Nancy, France Abstract The experimental study of the thermal decomposition of methyl decanoate was performed in a jet-stirred reactor at temperatures ranging from 773 to 1123 K, at residence times between 1 and 4 s, at a pressure of 800 Torr (106.6 kPa) and at high dilution in helium (fuel inlet mole fraction of 0.0218).
    [Show full text]
  • Methyleugenol (4-Allyl-1,2-Dimethoxybenzene)
    EUROPEAN COMMISSION HEALTH & CONSUMER PROTECTION DIRECTORATE-GENERAL Directorate C - Scientific Opinions C2 - Management of scientific committees II; scientific co-operation and networks Scientific Committee on Food SCF/CS/FLAV/FLAVOUR/4 ADD1 FINAL 26 September 2001 Opinion of the Scientific Committee on Food on Methyleugenol (4-Allyl-1,2-dimethoxybenzene) (adopted on 26 September 2001) Rue de la Loi 200, B-1049 Bruxelles/Wetstraat 200, B-1049 Brussel - Belgium - Office: F101 - 6/172 Telephone: direct line (+32-2) 295.4861, switchboard 299.11.11. Fax: (+32-2) 299.4891 Telex: COMEU B 21877. Telegraphic address: COMEUR Brussels http://europa.eu.int/comm/food/fs/sc/scf/index_en.html SCF/CS/FLAV/FLAVOUR/4 ADD1 FINAL Opinion of the Scientific Committee on Food on Methyleugenol (4-Allyl-1,2-dimethoxybenzene) (adopted on 26 September 2001) Terms of reference The Committee is asked to advise the Commission on substances used as flavouring substances or present in flavourings or present in other food ingredients with flavouring properties for which existing toxicological data indicate that restrictions of use or presence might be necessary to ensure safety for human health. In particular, the Committee is asked to advise the Commission on the implications for human health of methyleugenol (4-allyl-1,2-dimethoxybenzene) in the diet. Introduction In 1999 methyleugenol was evaluated by the Committee of Experts on Flavouring Substances of the Council of Europe. The conclusions of this Committee were: "Available data show that methyleugenol is a naturally-occurring genotoxic carcinogen compound with a DNA-binding potency similar to that of safrole. Human exposure to methyleugenol may occur through the consumption of foodstuffs flavoured with aromatic plants and/or their essential oil fractions which contain methyleugenol.
    [Show full text]
  • FEMA GRAS 29 December 2019 SUPPLEMENTARY INFORMATION 1
    SUPPLEMENTARY INFORMATION 1: Identity for Natural Flavor Complexes as Evaluated by the Expert Panel The Identification Description as Reviewed by the FEMA FEMA No.1 FEMA Primary Name Expert Panel Rebaudioside M ≥80%; Rebaudioside D 5-20%; Total 4895 Rebaudioside M steviol glycosides ≥95%. Glutamic acid 35-40%; Other amino acids 1-2%; Total Corynebacterium glutamicum corn nitrogen 6-7%; Aliphatic primary alcohols, aldehydes, 4907 syrup fermentation product carboxylic acids, acetals and esters containing additional oxygenated functional groups 1-2%; Minerals 9-11% Inosine 5´-monophosphate 20-25%; Amino acids 7-8%; Corynebacterium stationis corn 4908 Minerals 23-25%; water 28-37%; Other nucleotides 1-2%; syrup fermentation product Total nitrogen 5-8% Supraglucosylated steviol glycosides 70-80%; Rebaudioside Glucosylated steviol glycosides, 4909 A 14-20%; Steviol glycosides not further glucosylated, each 70-80% individually, not to exceed 3%; Maltodextrin 3-10% Supraglucosylated steviol glycosides 30-40%; Rebaudioside Glucosylated steviol glycosides, A 5-8%; Not more than 4% stevioside; All other individual 4910 40% steviol glycosides not further glucosylated <3%; Maltodextrin 45-60% Stevioside 70-80%; Rebaudioside A 13-18%; Steviobioside 1- 3%; Rebaudioside C 2-3%; Total glycosides (including 4911 Stevia extract stevioside, 70% Rebaudioside D, Rebaudioside B, Rebaudioside F, Dulcoside A, and Rubusoside) <3% Derived from hibiscus blossom calyces (Hibiscus sabdariffa L.) , Hibiscus blossom extract is measured as water 30-60%; 4912 Hibiscus
    [Show full text]
  • From Ultrathin Coatings to Laser Lithography
    Designing Functional 2D and 3D Structures: From Ultrathin Coatings to Laser Lithography Zur Erlangung des akademischen Grades eines DOKTORS DER NATURWISSENSCHAFTEN (Dr. rer. nat.) von der KIT-Fakultät für Chemie und Biowissenschaften des Karlsruher Instituts für Technologie (KIT) genehmigte DISSERTATION von M. Sc. Markus Michael Zieger aus Pforzheim, Deutschland 1. Referent: Prof. Dr. Christopher Barner-Kowollik 2. Referent: Prof. Dr. Hans-Achim Wagenknecht Tag der mündlichen Prüfung: 18.07.2018 Die vorliegende Arbeit wurde vom Februar 2015 bis Juni 2018 unter der Anleitung von Prof. Dr. Christopher Barner-Kowollik und Prof. Dr. Martin Wegener am Karlsruher Institut für Technologie (Universitätsbereich) angefertigt. iii Introduction In tiefer Dankbarkeit meiner Familie gewidmet. iv Hiermit erkläre ich wahrheitsgemäß, dass die vorliegende Doktorarbeit im Rahmen der Betreuung durch Prof. Dr. Christopher Barner-Kowollik von mir verfasst wurde und keine anderen als die angegebenen Quellen und Hilfsmittel verwendet wurden. Wörtlich oder inhaltlich übernommene Passagen sind mit dem entsprechenden Zitat kenntlich gemacht. Darüber hinaus wurde die Satzung des Karlsruher Instituts für Technologie (KIT) zur Sicherung guter wissenschaftlicher Praxis beachtet, insbesondere die Abgabe und Archivierung der Primärdaten gemäß Abs. A (6). Ebenfalls bestätige ich, dass die elektronische Version der Arbeit mit der schriftlich abgegebenen übereinstimmt. Des Weiteren erkläre ich, dass ich mich derzeit in keinem weiteren laufenden Promotionsverfahren befinde
    [Show full text]
  • Nicolet Condensed Phase Academic Sampler
    Nicolet Condensed Phase Academic Sampler Library Listing – 1,000 spectra This high resolution format library is suited to the needs of academic institutions and small QC labs. Chosen by chemistry professors from many disciplines, it includes spectra of chemicals used in a wide range of common laboratory experiments. The Nicolet Condensed Phase Academic Sampler includes 1,000 spectra of common chemicals representing the major functional groups and combinations of functional groups which are most likely to be observed in academic chemistry laboratories. These chemicals are also important building blocks commonly found in industrial applications. Thermo Nicolet Condensed Phase Academic Sampler Index Compound Name Index Compound Name 353 (+)-2-Phenyl-1-propanol, 97% 164 1,2,4,5-Tetramethylbenzene, 98% 768 (+)-4-Cholesten-3-one 161 1,2,4-Trimethylbenzene, 99+% 290 (+)-a-Lactose 254 1,2-Butanediol, 98% 262 (+)-b-Citronellol, 95% 499 1,2-Diaminopropane, 99% 344 (+/-)-1-Phenyl-1-propanol, 99% 128 1,2-Dibromoethylene, 98%, (Z) + (E) 101 (+/-)-2-Bromopentane, 97% 106 1,2-Dichloroethane, 99+% 228 (+/-)-2-Butanol, 99% 110 1,2-Dichloropropane, 99% 233 (+/-)-2-Heptanol, 96% 258 1,2-Pentanediol, tech., 95% 402 (+/-)-Camphor, 97% 550 1,2-Phenylenediamine, 98% 553 (+/-)-Epinephrine, 99% 77 1,3,5,7-Cyclooctatetraene, 98% 280 (+/-)-Isoborneol, 85% 45 1,3,5-Hexatriene 706 (+/-)-Warfarin, 98% 74 1,3-Cycloheptadiene, 97% 648 (+/-)-sec-Butyl acetate, 99% 72 1,3-Cyclohexadiene, 96% 490 (+/-)-sec-Butylamine, 99% 388 1,3-Cyclohexanedione, 97% 279 (-)-Borneol,
    [Show full text]
  • New Natural Agonists of the Transient Receptor Potential Ankyrin 1 (TRPA1
    www.nature.com/scientificreports OPEN New natural agonists of the transient receptor potential Ankyrin 1 (TRPA1) channel Coline Legrand, Jenny Meylan Merlini, Carole de Senarclens‑Bezençon & Stéphanie Michlig* The transient receptor potential (TRP) channels family are cationic channels involved in various physiological processes as pain, infammation, metabolism, swallowing function, gut motility, thermoregulation or adipogenesis. In the oral cavity, TRP channels are involved in chemesthesis, the sensory chemical transduction of spicy ingredients. Among them, TRPA1 is activated by natural molecules producing pungent, tingling or irritating sensations during their consumption. TRPA1 can be activated by diferent chemicals found in plants or spices such as the electrophiles isothiocyanates, thiosulfnates or unsaturated aldehydes. TRPA1 has been as well associated to various physiological mechanisms like gut motility, infammation or pain. Cinnamaldehyde, its well known potent agonist from cinnamon, is reported to impact metabolism and exert anti-obesity and anti-hyperglycemic efects. Recently, a structurally similar molecule to cinnamaldehyde, cuminaldehyde was shown to possess anti-obesity and anti-hyperglycemic efect as well. We hypothesized that both cinnamaldehyde and cuminaldehyde might exert this metabolic efects through TRPA1 activation and evaluated the impact of cuminaldehyde on TRPA1. The results presented here show that cuminaldehyde activates TRPA1 as well. Additionally, a new natural agonist of TRPA1, tiglic aldehyde, was identifed
    [Show full text]