Computer Program for Diagnosing and Teaching Geographic Me Dic Ine Stephen A

Total Page:16

File Type:pdf, Size:1020Kb

Computer Program for Diagnosing and Teaching Geographic Me Dic Ine Stephen A Computer Program for Diagnosing and Teaching Geographic Me dic ine Stephen A. Berger and Uri Blackman One of the unique aspects of infectious disease is its neighboring countries and previous years when neces- wide variety, both in time and place.The specialist prac- sary (Table 1). In cases where the accuracy of disease ticing in India may have little or no expertise in Peru- reporting was suspect (e.g.,AIDS in Africa), more real- vian disease.A colleague in NewYork may be called upon istic published estimates were used. to diagnose and treat conditions originating in Africa,Asia, The data base is limited to infectious diseases South America, Fiji and Papua, New Guinea. At the (Table 2). It does not include slow viral illnesses and a same time, this colleague must be familiar with the number of self-defined and obvious conditions such as pathogens that originate in Texas, Hawaii, and Canada. otitis externa and furunculosis.As the program is designed Indeed, even the full-time infectious diseases specialist may to diagnose clinically apparent disease, data regarding not be conversant in diseases such as lagochilascariasis, asymptomatic carriage or infestation were adjusted louping ill, and lobomycosis. War, famine, education, accordingly. Figures regarding the incidence of signs and immigration, and business travel have contributed to the symptoms within each specific disease were derived advent of specialists in Geographic Medicine and Empo- from standard textbooks and reviews. Clinical and epi- riatrics, otherwise known as Travel medicine. demiologic data are updated on a continous basis. The “art” of diagnosis is largely an ability (albeit sub- The program user is first requested to indicate the conscious) to rank probabilities based on the incidences country of disease origin and is then presented with a of likely diseases and the chance of encountering given list of 22 basic clinical parameters, which are grouped clinical features within each disease. In theory, Bayesian according to body system.A + or - response to each of analysis could be employed to diagnose disease accurately the latter is indicated by using any of a variety of com- when given proper input.A multicenter study was under- puter keystr0kes.A + response automatically opens a com- taken to test a comprehensive computer driven-soft- puter window that requests further details.Thus, if the ware program that incorporates worldwide epidemiologic user indicates that a rash is present, he will be asked to and clinical parameters. further define the nature and distribution of the skin lesions. An additional window is available for the entry Materials and Methods of laboratory test results (hematologic, cerebrospin, hepatic, or renal) if available. Computer Program Design User input is processed by a Bayesian matrix, and Interactive data bases that represent rates and clin- compatible diagnoses are presented in order of probability ical probabilities were constructed for 308 diseases; 127 in a bar graph and numerical format.Ancillary clues for symptoms, signs, and laboratory findings; and 205 coun- all listed diseases are accessed by specified key strokes as tries. Reported statistics published by the World Health follows: incubation period, clinical hints, geographic dis- Organization and national health ministries were used tribution, vector, vehicle, reservoir, etc.Additionally,drugs where available.These were supplemented by data for of choice and dosages for adult or pediatric therapy are 1isted.The diagnosis list is accompanied by an ancillary screen, which indicates rare (albeit compatible) clinical findings in each disease listed for the patient in question. Stephen A. Berger, MD, The Infectious Diseases Division, An additional interactive screen lists all additional clin- Tel-Aviv Sourasky Medical Center, and Uri Blackman, BS, The Department of Computer Science, University of Tel-Aviv, ical findings that could improve diagnostic specificity. Tel-Aviv, Israel Separate computer modules allow the user to study Participating study institutions: Soroka Medical Center, Beer specific diseases and antiinfective agents without regard Sheva [Pediatrics and Internal Medicine]; Edith Wolfson to a specific patient.The user may, for example, request Medical Center, Holon; Haemek Hospital, Afula; Chaim a listing for all parasitic diseases acquired in Togo from Sheba Medical Center, Tel Hashomer; Carmel Hospital, Haifa the bites of mosquitoes; or of all drugs which interact with Reprint requests: Stephen A. Berger, MD, Dept. of alcohol. In addition to the epidemiologic and clinical para- Microbiology, Tel Aviv Medical Center, 6 Weitzman Street, meters outlined above, screens are available that outline Tel Aviv 64239, Israel the worldwide distribution of each disease, as well as the J Travel Med 1995; 2199-203 current status ofAIDS, malaria, tuberculosis,yellow fever, 199 200 Journal of Travel Medicine, Volume 2, Number 3 Table 1 Sources Used in Maintaining The Epidemiologic Database Official Health Ministry Reports Archives of Internal Medicine Bericht Uber dat Gesundheitswesen in Osterreich British Melcal Journal [Austria] Bulletin of the World Health Organization Boletin Epidemiologico de Chile Clinical Infectious Diseases Boletin Epidemiologico Nacional [Argentina] Clinical Microbiology Reviews Boletin Epidemiologico y Microbiologico [Spain] European journal of Microbiology and Infectious Boletin lnformativo [Bolivia] Diseases Bulletin Epidemiologique Hebdomadaire [France] Harefuah Canada Communicable Disease Report [Canada] Infectious Disease Clinics CDR Weekly [United Kingdom] Infectious Disease Clinics of North America Choroby Zakazne I Zatrucia W Polsce [Poland] International Journal of Systematic Bacteriology Communicable Diseases Intelligence [Australia] Israel Journal of Medical Sciences Community Health & Disease Surveillance News Letter JAMA [Oman] journal of Antimicrobial Chemotherapy Comportamiento de Patologias Immunoprevenibles journal of Clinical Microbiology [Argentina] Journal of Clinical Pathology Daten des Gesundheitswesens [Germany] Journal of Hospital Infection EpidAktuellt [Sweden] Journal of Internal Medicine Epidemiology Bulletin [Taiwan] Journal of Infectious Diseases EPI-NYT [Denmark] Journal of Pediatrics Heilbrigdisskyrslur [Iceland] Journal ofTravel Medicine IASR Uapan] Lancet Health Statistics Ireland [Ireland] Medical Journal of Australia Monthly Epidemiological Bulletin [Israel] Medicine Morbidity and Mortality Weekly Report [USA] Morbidity and Mortality Weekly Report (CDC) MSIS-rapport [Norway] New England Journal of Medicine Notiziario dell’Instituto Superiore de Sanita [Italy] Pediatric Clinics of North America Terveys [Finland] The Pediatric Infectious Disease Journal Weekly Epidemiological Record [WHO] Pediatrics Journals and Periodicals Reviews of Infectious Diseases AIDS Scandinavian Journal of Infectious Diseases American Journal of Clinical Pathology South African Medical Journal American Journal of Diseases of Children Southern Medical Journal American Journal of Epidemiology The Medical Letter American Journal of Medicine Transactions of the Royal Society ofTropical Medicine American Journal of Public Health and Hygiene American Journal ofTropical Medicine and Hygiene Tubercle Annals of Internal Medicine World Health Statistics Quarterly Antimicrobial Agents and Chemotherapy Applied Microbiology and cholera. The therapeutic spectrum, toxicity, dosage results were collated and entered into a data base (dBase and other characteristics of anti-infective agents and III+) prior to to review of the clinical diagnoses. vaccines are also available. Statistical analysis employed the chi-square test for unpaired proportions. Multicenter Study Questionnaires reflecting the computer input screen Results were distributed to six senior full-time infectious dis- ease specialists. (The authors’ own institution was Four hundred ninety and five of 513 cases submit- excluded). Participants were requested to record all pos- ted were suitable for analysis (Table 3). Ninety four itive and negative clinical data for consecutive patients individual infectious diseases were represented among with established diagnoses. Since the majority of cases these cases (Table 2).The computer program accurately were anticipated to represent disease acquired in the study identified the clinical diagnosis in 75.3% of actual cases country (Israel) a similar number 0f“hypothetical” cases and in 64.0% of hypothetical cases (p = .009).The clin- acquired abroad was also elicited. Questionnaires were ical diagnosis was included in the computer differential assigned code numbers and submitted in a blinded fash- diagnosis list in 94.7%. The accuracy of diagnosis was ion, with diagnoses recorded on a separate sheet.AU highest for parasitic disease (p = .04) and diseases acquired Berger and Blackman, Computer Program for Diagnosing & Teaching Geographic Medicine 201 Table 2 Diseases and Pathogens Included in the Data Base Abscess, intraabdominal* Cutaneous larva migrans" Herpes simplex infection* Mycobacteriosis - M. Actinomycosis Cutaneous leishmaniasis* Herpes simplex encephalitis* ulcerans Adenovirus infection Cyclospora infection Herpesvirus simiae infection Mycobacteriosis - systemic* Aeromonas & marine Cysticercosis* Herpes zoster* Mycoplasma pneunioniae Vibrio infx. Cytomegalovirus infection* Heterophyiasis infec.* Myiasis* AIDS* Dengue* Histoplasmosis* Nanophyetiasis Amebiasis* Derniatophytosis Histoplasmosis - African Necrotizing skidsoft tissue Amoeba - free
Recommended publications
  • Diagnostic Code Descriptions (ICD9)
    INFECTIONS AND PARASITIC DISEASES INTESTINAL AND INFECTIOUS DISEASES (001 – 009.3) 001 CHOLERA 001.0 DUE TO VIBRIO CHOLERAE 001.1 DUE TO VIBRIO CHOLERAE EL TOR 001.9 UNSPECIFIED 002 TYPHOID AND PARATYPHOID FEVERS 002.0 TYPHOID FEVER 002.1 PARATYPHOID FEVER 'A' 002.2 PARATYPHOID FEVER 'B' 002.3 PARATYPHOID FEVER 'C' 002.9 PARATYPHOID FEVER, UNSPECIFIED 003 OTHER SALMONELLA INFECTIONS 003.0 SALMONELLA GASTROENTERITIS 003.1 SALMONELLA SEPTICAEMIA 003.2 LOCALIZED SALMONELLA INFECTIONS 003.8 OTHER 003.9 UNSPECIFIED 004 SHIGELLOSIS 004.0 SHIGELLA DYSENTERIAE 004.1 SHIGELLA FLEXNERI 004.2 SHIGELLA BOYDII 004.3 SHIGELLA SONNEI 004.8 OTHER 004.9 UNSPECIFIED 005 OTHER FOOD POISONING (BACTERIAL) 005.0 STAPHYLOCOCCAL FOOD POISONING 005.1 BOTULISM 005.2 FOOD POISONING DUE TO CLOSTRIDIUM PERFRINGENS (CL.WELCHII) 005.3 FOOD POISONING DUE TO OTHER CLOSTRIDIA 005.4 FOOD POISONING DUE TO VIBRIO PARAHAEMOLYTICUS 005.8 OTHER BACTERIAL FOOD POISONING 005.9 FOOD POISONING, UNSPECIFIED 006 AMOEBIASIS 006.0 ACUTE AMOEBIC DYSENTERY WITHOUT MENTION OF ABSCESS 006.1 CHRONIC INTESTINAL AMOEBIASIS WITHOUT MENTION OF ABSCESS 006.2 AMOEBIC NONDYSENTERIC COLITIS 006.3 AMOEBIC LIVER ABSCESS 006.4 AMOEBIC LUNG ABSCESS 006.5 AMOEBIC BRAIN ABSCESS 006.6 AMOEBIC SKIN ULCERATION 006.8 AMOEBIC INFECTION OF OTHER SITES 006.9 AMOEBIASIS, UNSPECIFIED 007 OTHER PROTOZOAL INTESTINAL DISEASES 007.0 BALANTIDIASIS 007.1 GIARDIASIS 007.2 COCCIDIOSIS 007.3 INTESTINAL TRICHOMONIASIS 007.8 OTHER PROTOZOAL INTESTINAL DISEASES 007.9 UNSPECIFIED 008 INTESTINAL INFECTIONS DUE TO OTHER ORGANISMS
    [Show full text]
  • WO 2014/134709 Al 12 September 2014 (12.09.2014) P O P C T
    (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (10) International Publication Number (43) International Publication Date WO 2014/134709 Al 12 September 2014 (12.09.2014) P O P C T (51) International Patent Classification: (81) Designated States (unless otherwise indicated, for every A61K 31/05 (2006.01) A61P 31/02 (2006.01) kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, (21) International Application Number: BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, PCT/CA20 14/000 174 DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, (22) International Filing Date: HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, 4 March 2014 (04.03.2014) KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, (25) Filing Language: English OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, (26) Publication Language: English SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, (30) Priority Data: ZW. 13/790,91 1 8 March 2013 (08.03.2013) US (84) Designated States (unless otherwise indicated, for every (71) Applicant: LABORATOIRE M2 [CA/CA]; 4005-A, rue kind of regional protection available): ARIPO (BW, GH, de la Garlock, Sherbrooke, Quebec J1L 1W9 (CA). GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, (72) Inventors: LEMIRE, Gaetan; 6505, rue de la fougere, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, Sherbrooke, Quebec JIN 3W3 (CA).
    [Show full text]
  • Rhinoscleroma in an Immigrant from Egypt: a Case Report
    387 BRIEF COMMUNICATION Rhinoscleroma in an Immigrant From Egypt: A Case Report Edgardo Bonacina, MD,∗ Leonardo Chianura, MD, DTM&H,† Maurizio Sberna, MD,‡ Giuseppe Ortisi, MD,§ Giovanna Gelosa, MD,|| Alberto Citterio, MD,‡ Giovanni Gesu, MD,§ and Massimo Puoti, MD† Downloaded from https://academic.oup.com/jtm/article/19/6/387/1795562 by guest on 23 September 2021 Departments of ∗Pathological Anatomy; †Infectious Diseases; ‡Neuroradiology; §Microbiology, and; ||Otorinolaringoiatry, Niguarda Ca` Granda Hospital, Milano, Italy DOI: 10.1111/j.1708-8305.2012.00659.x Rhinoscleroma is a chronic indolent granulomatous infection of the nose and the upper respiratory tract caused by Klebsiella rhinoscleromatis; this condition is endemic to many regions of the world including North Africa. We present a case of rhinoscleroma in a 51-year-old Egyptian immigrant with 1-month history of epistaxis. We would postulate that with increased travel from areas where rhinoscleroma is endemic to other non-endemic areas, diagnosis of this condition will become more common. hough rarely observed, rhinoscleroma has to be nasal fossae and ethmoid sinuses with complete bony T taken into consideration in travelers returning destruction of bilateral nasal turbinates (Figure 1). with ear, nose, and throat presentations, particularly Endoscopic biopsy was performed under local anesthe- after traveling to developing countries or regions where sia. Histopathologic examination revealed numerous this condition is endemic.1,2 foamy macrophages (Mikulicz cells) containing bacteria (Figure 2); no fungal hyphae were found.3 Staphylococcus Case Report aureus and Klebsiella rhinoscleromatis were isolated by culture of the tissue biopsy. A diagnosis of rhinoscle- A 51-year-old Egyptian male immigrant presented on roma was made.
    [Show full text]
  • Unusual Presentation of Rhinoscleroma Dehadaray A1, Patel M2, Kaushik M3, Agrawal D4
    Case Report Unusual presentation of Rhinoscleroma Dehadaray A1, Patel M2, Kaushik M3, Agrawal D4 ABSTRACT Rhinoscleroma or respiratory scleroma is a chronic, slowly progressive, inflammatory disease of the upper respiratory tract. Here we present a 35 year old male presenting with unilateral orbital complaints and non- specific findings on radiological examination, diagnosed only by histopathology as Rhinoscleroma. Due to the low incidence of this disease and its rare presentation in this case, diagnosis was a challenge, but outcome was successful. Keywords- Rhinoscleroma, Orbit 1 MS ENT, Professor, 2 MS DNB ENT, Assistant Professor, 3 MS ENT, Professor and Head, 4 PG student, Department of ENT and HNS, Bharati Vidyapeeth Deemed University Medical College, Pune-411043. Corresponding Author: Dr. Monika Patel, Assistant Professor, Bharati Vidyapeeth Deemed University Medical College, Pune, Maharashtra. Mob: +919028738326 Email: [email protected] 32 The Indian Practitioner q Vol.70 No.11. November 2017 Case Report Introduction hinoscleroma is a chronic progressive, specific granulomatous infectious disease affecting the Rupper respiratory tract associated with Klebsiella rhinoscleromatis infection. It is endemic in Central and South America, Central Africa, Middle East, parts of Europe, India, and Indonesia [1]. It most commonly af- fects the nose [2]. Cases of Rhinoscleroma with invasion into the or- bits are rare, with very few cases reported in litera- ture. Ophthalmologists should also be aware of the Fig 1a Fig 1b disease and the problems in its management. We pres- ent a case of Rhinoscleroma which posed difficulty in with reduced movements in all directions, and vision diagnosing due to its clinical resemblance with other of 6/18.
    [Show full text]
  • Rhinoscleroma
    Eur J Rhinol Allergy 2020; 3(2): 53-4 Image of Interest Rhinoscleroma Seepana Ramesh , Satvinder Singh Bakshi Department of ENT and Head & Neck Surgery, AIIMS Mangalagiri, Guntur, India A 22-year-old man presented with a 6-month history of bilateral nasal obstruction and nasal discharge that was associated with intermittent mild episodes of blood-tinged nasal discharge since 2 months. On examination, a pinkish irregular mass was observed in both the nostrils with complete obstruction of the right nostril. Computed tomography revealed a non-en- hanced homogeneous mass in the left frontal, ethmoid, and maxillary sinuses that extended to both the nasal cavities (Figure 1). Histopathology revealed fragments of granulation tissue with inflammatory cells comprising several foamy to vacuolated histiocytes and plasma cells, suggestive of rhinoscleroma (Figure 2). The patient underwent surgical debridement of the mass and received ciprofloxacin 500 mg twice daily for 6 weeks. He was asymptomatic at 4 months of follow-up. Rhinoscleroma is a chronic granulomatous disease affecting the region between the nose and the subglottis. It is caused by the gram-negative bacillus Klebsiella rhinoscleromatis and spreads by inhalation of contaminated droplets (1). The symptoms depend on the stage of the disease. In the atrophic stage, patients present with fetid nasal dis- charge and crusting, followed by the granulomatous stage, wherein patients develop epistaxis and nasal deformity, secondary to the destruction of the nasal cartilages (1). The final stage is the sclerotic stage, in which patients present with thick dense scars in the nose and upper airway, leading to complete nasal obstruction and even stridor due to laryngeal stenosis (1).
    [Show full text]
  • A Novel Murine Model of Rhinoscleroma Identifies Mikulicz Cells, the Disease Signature, As IL-10 Dependent Derivatives of Inflammatory Monocytes
    OPEN TRANSPARENT Research Article ACCESS PROCESS IL-10 controls maturation of Mikulicz cells A novel murine model of rhinoscleroma identifies Mikulicz cells, the disease signature, as IL-10 dependent derivatives of inflammatory monocytes Cindy Fevre1y, Ana S. Almeida2,3y, Solenne Taront2,3, Thierry Pedron2,3, Michel Huerre4, Marie-Christine Prevost5, Aure´lie Kieusseian6,7, Ana Cumano6,7, Sylvain Brisse1, Philippe J. Sansonetti2,3,8,Re´gis Tournebize2,3* Keywords: IL-10; inflammatory Rhinoscleroma is a human specific chronic disease characterized by the monocytes; Klebsiella; Mikulicz cell; formation of granuloma in the airways, caused by the bacterium Klebsiella rhinoscleroma pneumoniae subspecies rhinoscleromatis, a species very closely related to K. pneumoniae subspecies pneumoniae. It is characterized by the appearance of specific foamy macrophages called Mikulicz cells. However, very little is known DOI 10.1002/emmm.201202023 about the pathophysiological processes underlying rhinoscleroma. Herein, we Received September 14, 2012 characterized a murine model recapitulating the formation of Mikulicz cells in Revised January 31, 2013 lungs and identified them as atypical inflammatory monocytes specifically Accepted February 14, 2013 recruited from the bone marrow upon K. rhinoscleromatis infection in a CCR2- independent manner. While K. pneumoniae and K. rhinoscleromatis infections induced a classical inflammatory reaction, K. rhinoscleromatis infection was characterized by a strong production of IL-10 concomitant to the appearance of Mikulicz cells. Strikingly, in the absence of IL-10, very few Mikulicz cells were observed, confirming a crucial role of IL-10 in the establishment of a proper environment leading to the maturation of these atypical monocytes. This is the first characterization of the environment leading to Mikulicz cells maturation and their identification as inflammatory monocytes.
    [Show full text]
  • Lecture 1 ― INTRODUCTION INTO MICROBIOLOGY
    МИНИСТЕРСТВО ЗДРАВООХРАНЕНИЯ РЕСПУБЛИКИ БЕЛАРУСЬ УЧРЕЖДЕНИЕ ОБРАЗОВАНИЯ «ГОМЕЛЬСКИЙ ГОСУДАРСТВЕННЫЙ МЕДИЦИНСКИЙ УНИВЕРСИТЕТ» Кафедра микробиологии, вирусологии и иммунологии А. И. КОЗЛОВА, Д. В. ТАПАЛЬСКИЙ МИКРОБИОЛОГИЯ, ВИРУСОЛОГИЯ И ИММУНОЛОГИЯ Учебно-методическое пособие для студентов 2 и 3 курсов факультета по подготовке специалистов для зарубежных стран медицинских вузов MICROBIOLOGY, VIROLOGY AND IMMUNOLOGY Teaching workbook for 2 and 3 year students of the Faculty on preparation of experts for foreign countries of medical higher educational institutions Гомель ГомГМУ 2015 УДК 579+578+612.017.1(072)=111 ББК 28.4+28.3+28.073(2Англ)я73 К 59 Рецензенты: доктор медицинских наук, профессор, заведующий кафедрой клинической микробиологии Витебского государственного ордена Дружбы народов медицинского университета И. И. Генералов; кандидат медицинских наук, доцент, доцент кафедры эпидемиологии и микробиологии Белорусской медицинской академии последипломного образования О. В. Тонко Козлова, А. И. К 59 Микробиология, вирусология и иммунология: учеб.-метод. пособие для студентов 2 и 3 курсов факультета по подготовке специалистов для зарубежных стран медицинских вузов = Microbiology, virology and immunology: teaching workbook for 2 and 3 year students of the Faculty on preparation of experts for foreign countries of medical higher educa- tional institutions / А. И. Козлова, Д. В. Тапальский. — Гомель: Гом- ГМУ, 2015. — 240 с. ISBN 978-985-506-698-0 В учебно-методическом пособии представлены тезисы лекций по микробиоло- гии, вирусологии и иммунологии, рассмотрены вопросы морфологии, физиологии и генетики микроорганизмов, приведены сведения об общих механизмах функциони- рования системы иммунитета и современных иммунологических методах диагности- ки инфекционных и неинфекционных заболеваний. Приведены сведения об этиоло- гии, патогенезе, микробиологической диагностике и профилактике основных бакте- риальных и вирусных инфекционных заболеваний человека. Может быть использовано для закрепления материала, изученного в курсе микро- биологии, вирусологии, иммунологии.
    [Show full text]
  • Diagnosis One To
    Diagnosis One-to-One I9cm I9 Long Desc I10cm I10 Long Desc 0010 Cholera due to vibrio cholerae A000 Cholera due to Vibrio cholerae 01, biovar cholerae 0011 Cholera due to vibrio cholerae el tor A001 Cholera due to Vibrio cholerae 01, biovar eltor 0019 Cholera, unspecified A009 Cholera, unspecified 0021 Paratyphoid fever A A011 Paratyphoid fever A 0022 Paratyphoid fever B A012 Paratyphoid fever B 0023 Paratyphoid fever C A013 Paratyphoid fever C 0029 Paratyphoid fever, unspecified A014 Paratyphoid fever, unspecified 0030 Salmonella gastroenteritis A020 Salmonella enteritis 0031 Salmonella septicemia A021 Salmonella sepsis 00320 Localized salmonella infection, unspecified A0220 Localized salmonella infection, unspecified 00321 Salmonella meningitis A0221 Salmonella meningitis 00322 Salmonella pneumonia A0222 Salmonella pneumonia 00323 Salmonella arthritis A0223 Salmonella arthritis 00324 Salmonella osteomyelitis A0224 Salmonella osteomyelitis 0038 Other specified salmonella infections A028 Other specified salmonella infections 0039 Salmonella infection, unspecified A029 Salmonella infection, unspecified 0040 Shigella dysenteriae A030 Shigellosis due to Shigella dysenteriae 0041 Shigella flexneri A031 Shigellosis due to Shigella flexneri 0042 Shigella boydii A032 Shigellosis due to Shigella boydii 0043 Shigella sonnei A033 Shigellosis due to Shigella sonnei 0048 Other specified shigella infections A038 Other shigellosis 0049 Shigellosis, unspecified A039 Shigellosis, unspecified 0050 Staphylococcal food poisoning A050 Foodborne staphylococcal
    [Show full text]
  • Infectious Diseases of the Philippines
    INFECTIOUS DISEASES OF THE PHILIPPINES Stephen Berger, MD Infectious Diseases of the Philippines - 2013 edition Infectious Diseases of the Philippines - 2013 edition Stephen Berger, MD Copyright © 2013 by GIDEON Informatics, Inc. All rights reserved. Published by GIDEON Informatics, Inc, Los Angeles, California, USA. www.gideononline.com Cover design by GIDEON Informatics, Inc No part of this book may be reproduced or transmitted in any form or by any means without written permission from the publisher. Contact GIDEON Informatics at [email protected]. ISBN-13: 978-1-61755-582-4 ISBN-10: 1-61755-582-7 Visit http://www.gideononline.com/ebooks/ for the up to date list of GIDEON ebooks. DISCLAIMER: Publisher assumes no liability to patients with respect to the actions of physicians, health care facilities and other users, and is not responsible for any injury, death or damage resulting from the use, misuse or interpretation of information obtained through this book. Therapeutic options listed are limited to published studies and reviews. Therapy should not be undertaken without a thorough assessment of the indications, contraindications and side effects of any prospective drug or intervention. Furthermore, the data for the book are largely derived from incidence and prevalence statistics whose accuracy will vary widely for individual diseases and countries. Changes in endemicity, incidence, and drugs of choice may occur. The list of drugs, infectious diseases and even country names will vary with time. Scope of Content: Disease designations may reflect a specific pathogen (ie, Adenovirus infection), generic pathology (Pneumonia - bacterial) or etiologic grouping (Coltiviruses - Old world). Such classification reflects the clinical approach to disease allocation in the Infectious Diseases Module of the GIDEON web application.
    [Show full text]
  • PCR-Based Identification of Klebsiella Pneumoniae Subsp
    PCR-based identification of Klebsiella pneumoniae subsp. rhinoscleromatis, the agent of rhinoscleroma. Cindy Fevre, Virginie Passet, Alexis Deletoile, Valérie Barbe, Lionel Frangeul, Ana Almeida, Philippe Sansonetti, Régis Tournebize, Sylvain Brisse To cite this version: Cindy Fevre, Virginie Passet, Alexis Deletoile, Valérie Barbe, Lionel Frangeul, et al.. PCR-based identification of Klebsiella pneumoniae subsp. rhinoscleromatis, the agent of rhinoscleroma.. PLoS Neglected Tropical Diseases, Public Library of Science, 2011, 5 (5), pp.e1052. 10.1371/jour- nal.pntd.0001052. inserm-00691408 HAL Id: inserm-00691408 https://www.hal.inserm.fr/inserm-00691408 Submitted on 26 Apr 2012 HAL is a multi-disciplinary open access L’archive ouverte pluridisciplinaire HAL, est archive for the deposit and dissemination of sci- destinée au dépôt et à la diffusion de documents entific research documents, whether they are pub- scientifiques de niveau recherche, publiés ou non, lished or not. The documents may come from émanant des établissements d’enseignement et de teaching and research institutions in France or recherche français ou étrangers, des laboratoires abroad, or from public or private research centers. publics ou privés. PCR-Based Identification of Klebsiella pneumoniae subsp. rhinoscleromatis, the Agent of Rhinoscleroma Cindy Fevre1, Virginie Passet1, Alexis Deletoile1, Vale´ rie Barbe2, Lionel Frangeul3, Ana S. Almeida4,5, Philippe Sansonetti4,5,Re´gis Tournebize4,5, Sylvain Brisse1* 1 Institut Pasteur, Genotyping of Pathogens and Public Health, Paris, France, 2 CEA-IG, Genoscope, Evry, France, 3 Institut Pasteur, Inte´gration et Analyse Ge´nomique, Paris, France, 4 Institut Pasteur, Unite´ de Pathoge´nie Microbienne Mole´culaire, Paris, France, 5 Unite´ INSERM U786, Institut Pasteur, Paris, France Abstract Rhinoscleroma is a chronic granulomatous infection of the upper airways caused by the bacterium Klebsiella pneumoniae subsp.
    [Show full text]
  • Infectious Diseases of the Dominican Republic
    INFECTIOUS DISEASES OF THE DOMINICAN REPUBLIC Stephen Berger, MD 2018 Edition Infectious Diseases of the Dominican Republic Copyright Infectious Diseases of the Dominican Republic - 2018 edition Stephen Berger, MD Copyright © 2018 by GIDEON Informatics, Inc. All rights reserved. Published by GIDEON Informatics, Inc, Los Angeles, California, USA. www.gideononline.com Cover design by GIDEON Informatics, Inc No part of this book may be reproduced or transmitted in any form or by any means without written permission from the publisher. Contact GIDEON Informatics at [email protected]. ISBN: 978-1-4988-1759-2 Visit www.gideononline.com/ebooks/ for the up to date list of GIDEON ebooks. DISCLAIMER Publisher assumes no liability to patients with respect to the actions of physicians, health care facilities and other users, and is not responsible for any injury, death or damage resulting from the use, misuse or interpretation of information obtained through this book. Therapeutic options listed are limited to published studies and reviews. Therapy should not be undertaken without a thorough assessment of the indications, contraindications and side effects of any prospective drug or intervention. Furthermore, the data for the book are largely derived from incidence and prevalence statistics whose accuracy will vary widely for individual diseases and countries. Changes in endemicity, incidence, and drugs of choice may occur. The list of drugs, infectious diseases and even country names will vary with time. Scope of Content Disease designations may reflect a specific pathogen (ie, Adenovirus infection), generic pathology (Pneumonia - bacterial) or etiologic grouping (Coltiviruses - Old world). Such classification reflects the clinical approach to disease allocation in the Infectious Diseases Module of the GIDEON web application.
    [Show full text]
  • Report for the Hemodialysis Vascular Access: Standardized Fistula Rate
    ESRD Quality Measure Development, Maintenance, and Support Contract Number HHSM-500-2013-13017I Report for the Hemodialysis Vascular Access: Standardized Fistula Rate (SFR) NQF #2977 Submitted to CMS by the University of Michigan Kidney Epidemiology and Cost Center June 21, 2017 Produced by UM-KECC Submitted: 6.21.2017 1 ESRD Quality Measure Development, Maintenance, and Support Contract Number HHSM-500-2013-13017I Table of Contents Introduction .................................................................................................................................................. 3 Methods ........................................................................................................................................................ 3 Overview ................................................................................................................................................... 3 Data Sources ............................................................................................................................................. 4 Outcome Definition .................................................................................................................................. 4 Denominator Definition ............................................................................................................................ 5 Risk Adjustment ........................................................................................................................................ 5 Choosing Adjustment Factors
    [Show full text]