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RIKEN IMS Annual Report  RIKEN Center for Integrative Medical Sciences  T Jp English/ Cells

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RIKEN IMS Annual Report  RIKEN Center for Integrative Medical Sciences  T Jp English/ Cells RIKEN IMS Annual RIKEN Center for Repo Integrative Medical Sciences http://www.ims.riken.jp/english/ r t RIKEN Yokohama Campus 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, 230-0045, Japan RIKEN Center for Integrative Medical Sciences Integrative Medical for Center RIKEN Tel : 045-503-9111 Fax : 045-503-9113 Email : [email protected] RIKEN IMS Annual Report RIKEN IMS Annual Report RIKEN Center for Integrative Medical Sciences Cover image: Preparation of glass-supported lipid bilayers for analyzing molecular dynamics of microclusters in Jurkat T cells. Image courtesy of Laboratory for Molecular Live-cell Quantification. RIKEN - RIKEN Center for Integrative Medical Sciences Access to RIKEN Yokohama Campus Organization Chart Local Access RIKEN President By Bus Ryoji Noyori Director Take the #08 bus from Platform 8 at the East Exit of Tsurumi Station (also accessible from the West Exit of Keikyu Tsurumi Station) and get off at the RIKEN Shigeo Koyasu Shidai Daigakuin Mae bus stop. The institute is across the street. All buses from this platform are bound for Fureyu. Buses depart Tsurumi every 5–15 minutes. It takes about 15 minutes to arrive at RIKEN Yokohama. The fare is 220 yen in cash. Deputy Director By Train A 15-minute walk from JR Tsurumi-Ono Station (JR Michiaki Kubo Tsurumi Line), which is directly accessible by transfer from JR Tsurumi Station. Takashi Saito Haruhiko Koseki Trains run about every 10 minutes during morning and evening rush hour, but less frequently at other times. Integrative Medical Sciences Toshihiro Tanaka Planning Oce Searchable train timetables in English are available at http://www.hyperdia.com/en/ By Taxi Use the taxi stand at the East Exit of JR Tsurumi Station or the West Exit of Keikyu Tsurumi Station. The trip takes about 10 minutes and costs around 1,200 yen. Core for Homeostatic Core for Precise Measuring From the Airport Regulation and Modeling From Haneda Airport From Narita Airport Lab. for Cell Signaling: Takashi Saito Lab. for Developmental Genetics: Haruhiko Koseki Route 1 From Narita Airport Station take the JR Sobu Line Lab. for Lymphocyte Dierentiation: Tomohiro Kurosaki Lab. for Integrative Genomics: Osamu Ohara Take the Keikyu Railways Airport Express* (blue kanji (Rapid Express), Airport Limousine Bus or JR Narita sign) for Yokohama and get off at Keikyu Tsurumi Express* to JR Shinagawa Station. (JR Sobu Line is the Lab. for Transcriptional Regulation: Ichiro Taniuchi Lab. for Disease Systems Modeling: Hiroaki Kitano Station (27–29 minutes). Airport Express trains run most inexpensive option and takes about 1 hour and 15 every 10-15 minutes between 9:30 a.m. and 9:30 p.m. minutes). From JR Shinagawa Station take the JR Keihin Lab. for Immune Cell Systems: Shigeo Koyasu Lab. for Cell Functional Imaging: Shigeo Koyasu Next, follow the Local Access directions above to get to Tohoku Line (Yokohama direction) to JR Tsurumi Station RIKEN Yokohama. (18 minutes). Next, follow the Local Access directions Lab. for Human Disease Models: Fumihiko Ishikawa Lab. for Immunogenetics: Hisahiro Yoshida above to get to RIKEN Yokohama. Lab. for Intestinal Ecosystem: Hiroshi Ohno Lab. for Integrated Bioinformatics: Todd Duane Taylor Route 2 * A reserved seat express that requires payment of a Take any train marked with a green (express), red or surcharge in addition to train fare. Lab. for Mucosal Immunity: Sidonia Fagarasan Lab. for Tissue Dynamics: Takaharu Okada dark grey kanji sign to Keikyu Kamata Station. Transfer to the Keikyu Main Line and take a local train* toward Searchable train timetables in English are available at Lab. for Gut Homeostasis: Kenya Honda Lab. for Integrated Cellular Systems: Mariko Okada Yokohama until Keikyu Tsurumi Station* (12 minutes). http://www.hyperdia.com/en/ Shohei Hori Makio Tokunaga Lab. for Immune Homeostasis: Lab. for Molecular Live-Cell Quantication: *Only Airport Express (blue kanji sign) and local trains (dark grey kanji sign) stop at Keikyu Tsurumi Station. Lab. for Skin Homeostasis: Masayuki Amagai Lab. for Metabolomics: Makoto Arita Note that Keikyu Tsurumi Station and JR Tsurumi Station are two different railway stations and are separated by Lab. for Metabolic Homeostasis: Naoto Kubota a bus rotary (the stations are about 150 meters apart). Lab. for Immune Crosstalk: Hilde Cheroutre Lab. for Inammatory Regulation: Takashi Tanaka Lab. for Cytokine Regulation: Masato Kubo Lab. for Homeostatic Network: Shigeo Koyasu RIKEN Center for Integrative Medical Sciences Advisory Council Max Cooper (chair) Peter Sorger Mark Lathrop (vice chair) Rudi Balling Ronald N. Germain Kiyoshi Takatsu Paul W. Kincade Hajime Karasuyama Bernard Malissen Yutaka Kawakami William E. Paul Michel Georges Senior Advisor Dale Umetsu Edison Tak-Bun Liu Arthur Weiss Katsushi Tokunaga Masaru Taniguchi John O’Shea Hiroyuki Aburatani Shizuo Akira Fiona Powrie Core for Genomic Medicine Program for Medical Innovations Lab. for Genotyping Development: Michiaki Kubo Lab. for Immune Regulation: Masaru Taniguchi Lab. for Genome Sequencing Analysis: Hidewaki Nakagawa Lab. for Immunotherapy: Shin-ichiro Fujii Lab. for Medical Science Mathematics: Tatsuhiko Tsunoda Lab. for Vaccine Design: Yasuyuki Ishii Lab. for Statistical Analysis: Atsushi Takahashi Lab. for Allergic Disease: Toshiaki Kawakami Lab. for Pharmacogenomics: Taisei Mushiroda RIKEN-TORII Joint Research Team: Masaru Taniguchi Lab. for International Alliance on Genomic Research: Drug Discovery Antibody Platform Unit: Toshitada Takemori Ming Ta Michael Lee Lab. for Cardiovascular Diseases: Toshihiro Tanaka Lab. for Autoimmune Diseases: Kazuhiko Yamamoto Lab. for Digestive Diseases: Kazuaki Chayama Lab. for Bone and Joint Diseases: Shiro Ikegawa Lab. for Endocrinology, Metabolism and Kidney Diseases: Shiro Maeda Lab. for Respiratory and Allergic Diseases: Mayumi Tamari Contents Organization .......................................................................... Director’s Report ................................................................... Contents ................................................................................. Part 1 Lab Activities Core for Homeostatic Regulation ........................... Laboratory for Digestive Diseases ................................ Laboratory for Cell Signaling ........................................ Laboratory for Bone and Joint Diseases ....................... Laboratory for Lymphocyte Dierentiation ................ Laboratory for Endocrinology, Metabolism and Laboratory for Transcriptional Regulation .................. Kidney Diseases ........................................................ Laboratory for Immune Cell Systems .......................... Laboratory for Respiratory and Allergic Diseases ...... Laboratory for Human Disease Models ....................... Program for Medical Innovations .......................... Laboratory for Intestinal Ecosystem ............................ Laboratory for Immune Regulation ............................. Laboratory for Mucosal Immunity ............................... Laboratory for Immunotherapy .................................... Laboratory for Gut Homeostasis .................................. Laboratory for Vaccine Design ..................................... Laboratory for Immune Homeostasis .......................... Laboratory for Allergic Disease .................................... Laboratory for Skin Homeostasis ................................. RIKEN-TORII Joint Research Team ............................ Laboratory for Metabolic Homeostasis ........................ Drug Discovery Antibody Platform Unit .................... Laboratory for Immune Crosstalk ................................ Central Facilities Laboratory for Inammatory Regulation .................... FACS Laboratory ............................................................ Laboratory for Cytokine Regulation ............................ Confocal Laboratory ...................................................... Core for Precise Measuring and Modeling ......... Genomics Laboratory ..................................................... Laboratory for Developmental Genetics ...................... Animal Facility ................................................................ Laboratory for Integrative Genomics ........................... Young Chief Investigator Program ......................... Laboratory for Disease Systems Modeling (LDSM) ... YCI Laboratory for Mathematical Modeling of Laboratory for Immunogenetics ................................... Immune System ........................................................ Laboratory for Integrated Bioinformatics .................... YCI Laboratory for Stem Cell Competency ................ Laboratory for Tissue Dynamics .................................. YCI Laboratory for Immune Regeneration ................. Laboratory for Integrated Cellular Systems ................. YCI Laboratory for Quantitative Omics ...................... Laboratory for Molecular Live-Cell Quantication ... YCI Laboratory for Cellular Bioenergetic Network ... Laboratory for Metabolomics ....................................... Award Winners 2014 .................................................... Core for Genomic Medicine ....................................... Other Programs Laboratory for Genotyping Development ................... RIKEN International Program Associate (IPA) .......... Laboratory for Genome Sequencing Analysis ............. RIKEN Foreign Postdoctoral
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