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About ICBME Conference Series Iv ICBME 2013 The 15th International Conference on Biomedical Engineering The 15 4 – 7 December 2013, Singapore th www.icbme.org Internationalon Biomedical Engineering Conference Jointly organised by 1 ISBN 978-981-07-8365-5 Department of Biomedical Engineering Society 9 789810 783655 www.icbme.org Biomedical Engineering (Singapore) Copyright © 2013 Biomedical Engineering Society (Singapore). All rights reserved. Design, Typeset & Printed by Research Publishing Services | Email: [email protected] PROGRAMME & ABSTRACTS ICBME2013_Front-Matter.qxd 11/26/2013 6:20 PM Page i The 15th International Conference on Biomedical Engineering (ICBME 2013) 4 – 7 December 2013, Singapore Foreword On behalf of the organising committee of the International Conference on Biomedical Engineering (ICBME) 2013, we would like to warmly welcome you to this meeting. This conference is part of a series that began in 1983 and is jointly organised by the Faculty of Engineering of the National University of Singapore (NUS) and the Biomedical Engineering Society (Singapore) (BES). This con- ference is also endorsed by the International Federation for Medical and Biological Engineering (IFMBE). We are happy to report that we have more than 600 participants from 35 countries. We have received very high quality papers and as a result, we had to decline a substantial number of papers. In this conference proceedings, we have published 245 papers with 6 being symposium papers, 11 Young Investigator Awards (YIA) papers, 118 oral presentation papers and 110 Poster papers. We are also very honoured to have invited very prominent speakers. Each of these speakers is an authority in their own field of expertise and we are grateful that they are able to take time to participate in this conference. In this conference, we have also included a design competition jointly organised by the BES and the Society of Engineers for the Community (SEC). The focus of the competition is on the design of a low-cost medical device to improve healthcare in resource-scarce communities. The competition is opened to teams comprising up to five bona-fide students. We are pleased to report that we have 12 entries from 8 countries. While the success of this conference lies in the participation of the delegates and the quality of papers presented, we are also mindful of the efforts put in by many of the volunteers, reviewers, as well as the members of the Organising Committee and the International Advisory Committee. Their dedicated contributions to this meeting are very much acknowledged and appreciated. We would also like to sincerely thank our sponsors, supporters and exhibitors for contributing to the success of this con- ference. Finally, we would like to thank the staff of INMEET CMS who has ensured the smooth running of the conference. Finally, to all our delegates, I hope the 15th ICBME 2013 will not only be one where excellent scientific exchanges are facilitated, but also one where old friendships are renewed and new friends made. Do enjoy the conference as well as the sights and sounds of Singapore! Best wishes, Prof. James GOH Chairman Prof. Chwee Teck LIM Scientific Program Chair 15th ICBME Organising Committee i ICBME2013_Front-Matter.qxd 11/26/2013 6:20 PM Page ii ICBME2013_Front-Matter.qxd 11/26/2013 6:20 PM Page iii The 15th International Conference on Biomedical Engineering (ICBME 2013) 4 – 7 December 2013, Singapore Table of Contents Foreword i About ICBME Conference Series iv Organisers iv Committees vii Themes & Topics x Speakers xi Symposia xiii Acknowledgements xv General Information xvi Programme Day 1 — Wednesday, 4 December 2013 P-3 Day 2 — Thursday, 5 December 2013 P-15 Day 3 — Friday, 6 December 2013 P-28 Day 4 — Saturday, 7 December 2013 P-41 Abstracts Day 1 — Wednesday, 4 December 2013 3 Day 2 — Thursday, 5 December 2013 44 Day 3 — Friday, 6 December 2013 88 Day 4 — Saturday, 7 December 2013 130 Poster Abstracts Day 1 — Wednesday, 4 December 2013 155 Day 2 — Thursday, 5 December 2013 180 Day 3 — Friday, 6 December 2013 204 Author Index 231 iii ICBME2013_Front-Matter.qxd 11/27/2013 11:46 AM Page iv The 15th International Conference on Biomedical Engineering (ICBME 2013) 4 – 7 December 2013, Singapore About ICBME Conference Series The ICBME is a series of international conference in biomedical engineering held in Singapore. Our past conferences have been successful in attracting over 600 participants from more than 40 countries. The next conference will be hosted from 4–7 December 2013 in Singapore. Biomedical engineering is applied in most aspects of our healthcare ecosystem. From electronic health records to diagnostic tools to therapeutic, rehabilitative and regenerative treatments, the work of biomedical engineers is evident. Biomedical engineers work at the intersection of engineering, life sciences and healthcare. The engineers would use principles from applied science including mechanical, electrical, chemical and computer engineering together with physical sciences including physics, chemistry and mathematics to apply them to biology and medicine. Applying such concepts to the human body is very much the same concepts that go into building and programming a machine. The goal is to better understand, replace or fix a target system to ultimately improve the quality of healthcare. With this understanding, we have created the International Conference in BioMedical Engineering to offer a single platform for individuals and organisations working in the biomedical engineering related field to gather and network with each other in so doing create the catalyst for future development of biomedical engineering in Asia. The 15th International Conference on Biomedical Engineering is endorsed by the International Federation for Medical and Biological Engineering (IFMBE). iv ICBME2013_Front-Matter.qxd 11/26/2013 6:21 PM Page v The 15th International Conference on Biomedical Engineering (ICBME 2013) 4 – 7 December 2013, Singapore Organisers Biomedical Engineering Society (Singapore) The Biomedical Engineering Society (Singapore) had its humble beginning in 1991, when a group of doctors and engineers who had been working together on biomedical engineering research projects decided to form a society to promote the field of Biomedical Engineering in Singapore. The Founding President was Prof Kamal Bose an Orthopaedic Surgeon with a passion for interdisciplinary collaboration. He steered the Society during its early years and set the sight for academic excellence in biomedical engineering. He left a lasting legacy of successful conferences on biomedical engineering organised by the Society. Prof Chew Yong Tian succeeded Prof Bose as the second President of BES. Prof Chew, a Mechanical Engineer led the Society to greater heights. The conferences organised by the Society achieved international status. Indeed, BES successfully hosted the 6th World Congress on Biomechanics in 2010 which saw 1600 participants from 42 countries around the world congregating in Singapore’s Suntec City Convention Centre. Prof Bose and Prof Chew had laid the strong foundation for the building of the Society. In view of BES’ academic strength and its association to the various tertiary institutions, BES set up a Student Chapter in 2009. The Student Chapter organises the BES’ Scientific Meetings with participation of students from Junior Colleges, Polytechnics and Universities. BES launched the Industry Chapter on the 12th November 2011 as part of its 20th Anniversary Celebration. Apart from creating these two synergistic platforms to address human capital development for the biomedical industry locally and regionally, BES is also well connected around the world. BES is affiliated to the International Federation of Medical and Biological Engineering (IFMBE) since 1994. It allows the Society to plug into 65 sister societies around the world, boasting a total membership of 120,000 biomedical engineers. National University of Singapore, Department of Biomedical Engineering, Faculty of Engineering The NUS’ Department of Biomedical Engineering is a University Department which was established in 2002. Our talented academic staff has varied background in engineering, life sciences and medicine. Many of whom has joint appointments with either the YLL School of Medicine, Faculty of Science, Faculty of Engineering, Mechanobiology Institute or A*STAR Research Institutes. This is a reflection of the multidisciplinary and integrative approach we take in bioengineering research and education. Broadly speaking, the core research expertise available in the department include Biomaterials, Biomechanics, Bionanotechnology, Biosignal Processing, Biosensors, Biomicrofluidics, Computational Methods with application in areas of Tissue Engineering, Therapeutic Delivery Systems, Biomedical Imaging and Instrumentation, and Medical Devices just to name a few. Last v ICBME2013_Front-Matter.qxd 11/26/2013 6:21 PM Page vi The 15th International Conference on Biomedical Engineering (ICBME 2013) 4 – 7 December 2013, Singapore year, the total research funding received was more than S$4.5 million. Several breakthrough projects were undertaken, for example, Associate Professor Zhang Yong led a team to develop a user-friendly method to produce nanocrystals with strong “up-conversion” fluorescence at low temperature which could be used for treating malignant melanoma. Another team led by Assistant Professor Chen Nanguang made significant headway in the development of diffuse optical tomography which may lead to a potential clinical
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