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Curriculum Vitae Prof. Dr. John Howard Northrop
Curriculum Vitae Prof. Dr. John Howard Northrop Name: John Howard Northrop Lebensdaten: 5. Juli 1891 ‐ 27. Mai 1987 John Howard Northrop war ein US‐amerikanischer Biochemiker, Biophysiker und Bakteriologe. Er lieferte Arbeiten zur Charakterisierung von Proteinen. Darüber hinaus listete er Grundsätze auf, die bei der Isolierung und Reindarstellung von Enzymen generell beobachtet werden können. Außerdem entwickelte er experimentelle Methoden, mit denen nachgewiesen werden konnte, dass kristallisierte Proteine reine Verbindungen sind, die volle Enzymaktivität besitzen. Für die Darstellung von Enzymen und Virusproteinen in reiner Form wurde er 1946 gemeinsam mit seinem Landsmann, dem Biochemiker Wendell Meredith Stanley, mit dem Nobelpreis für Chemie ausgezeichnet. Akademischer und beruflicher Werdegang John Howard Northrop studierte ab 1908 Chemie und Zoologie an der Columbia University in New York. Die Ausbildung schloss er 1912 mit einem Bachelor of Science ab. Ein Jahr später erhielt er den Master of Arts. 1915 wurde er im Fach Chemie promoviert. Im Anschluss war er mit einem Stipendium am Jacques Loeb Laboratory tätig, das zum Rockefeller Institute gehört. 1916 nahm man ihn in den Mitarbeiterstab des Rockefeller Institute for Medical Research auf, 1924 wurde er Vollmitglied. Northrop blieb dort bis zu seiner Emeritierung im Jahr 1961. Während des Ersten Weltkriegs verpflichtete sich Northrop für den Kriegsdienst. Er war im Rang eines Hauptmanns tätig. Nach Kriegsende wandte er sich wieder seiner Forschungsarbeit am Rockefeller Institute in New York zu. 1939 war Northrop Gastprofessor an der University of California; ein Jahr später Lektor an der John Hopkins University. 1942 wurde er in die National Defense Research Commission berufen, ein Gremium, über das die amerikanische Forschung während des Zweiten Weltkriegs koordiniert Nationale Akademie der Wissenschaften Leopoldina www.leopoldina.org 1 wurde. -
Plant Viruses
Western Plant Diagnostic Network1 First Detector News A Quarterly Pest Update for WPDN First Detectors Spring 2015 edition, volume 8, number 2 In this Issue Page 1: Editor’s Note Dear First Detectors, Pages 2 – 3: Intro to Plant Plant viruses cause many important plant diseases and are Viruses responsible for huge losses in crop production and quality in Page 4: Virus nomenclature all parts of the world. Plant viruses can spread very quickly because many are vectored by insects such as aphids and Page 5 – Most Serious World Plant Viruses & Symptoms whitefly. They are a major pest of crop production as well as major pests of home gardens. By mid-summer many fields, Pages 6 – 7: Plant Virus vineyards, orchards, and gardens will see the effects of plant Vectors viruses. The focus of this edition is the origin, discovery, taxonomy, vectors, and the effects of virus infection in Pages 7 - 10: Grapevine plants. There is also a feature article on grapevine viruses. Viruses And, as usual, there are some pest updates from the West. Page 10: Pest Alerts On June 16 – 18, the WPDN is sponsoring the second Invasive Snail and Slug workshop at UC Davis. The workshop Contact us at the WPDN Regional will be recorded and will be posted on the WPDN and NPDN Center at UC Davis: home pages. Have a great summer and here’s hoping for Phone: 530 754 2255 rain! Email: [email protected] Web: https://wpdn.org Please find the NPDN family of newsletters at: Editor: Richard W. Hoenisch @Copyright Regents of the Newsletters University of California All Rights Reserved Western Plant Diagnostic Network News Plant Viruses 2 Ag, Manitoba Photo courtesy Photo Food, and Rural Initiatives and Food, of APS Photo by Giovanni Martelli, U of byBari Giovanni Photo Grapevine Fanleaf Virus Peanut leaf with Squash Mosaic Virus tomato spotted wilt virus Viruses are infectious pathogens that are too small to be seen with a light microscope, but despite their small size they can cause chaos. -
Timeline of Genomics (1901–1950)*
Research Resource Timeline of Genomics (1901{1950)* Year Event and Theoretical Implication/Extension Reference 1901 Hugo de Vries adopts the term MUTATION to de Vries, H. 1901. Die Mutationstheorie. describe sudden, spontaneous, drastic alterations in Veit, Leipzig, Germany. the hereditary material of Oenothera. Thomas Harrison Montgomery studies sper- 1. Montgomery, T.H. 1898. The spermato- matogenesis in various species of Hemiptera and ¯nds genesis in Pentatoma up to the formation that maternal chromosomes only pair with paternal of the spermatid. Zool. Jahrb. 12: 1-88. chromosomes during meiosis. 2. Montgomery, T.H. 1901. A study of the chromosomes of the germ cells of the Metazoa. Trans. Am. Phil. Soc. 20: 154-236. Clarence Ervin McClung postulates that the so- McClung, C.E. 1901. Notes on the acces- called accessory chromosome (now known as the \X" sory chromosome. Anat. Anz. 20: 220- chromosome) is male determining. 226. Hermann Emil Fischer(1902 Nobel Prize Laure- 1. Fischer, E. and Fourneau, E. 1901. UberÄ ate for Chemistry) and Ernest Fourneau report einige Derivate des Glykocolls. Ber. the synthesis of the ¯rst dipeptide, glycylglycine. In Dtsch. Chem. Ges. 34: 2868-2877. 1902 Fischer introduces the term PEPTIDES. 2. Fischer, E. 1907. Syntheses of polypep- tides. XVII. Ber. Dtsch. Chem. Ges. 40: 1754-1767. 1902 Theodor Boveri and Walter Stanborough Sut- 1. Boveri, T. 1902. UberÄ mehrpolige Mi- ton found the chromosome theory of heredity inde- tosen als Mittel zur Analyse des Zellkerns. pendently. Verh. Phys -med. Ges. WÄurzberg NF 35: 67-90. 2. Boveri, T. 1903. UberÄ die Konstitution der chromatischen Kernsubstanz. Verh. Zool. -
Federation Member Society Nobel Laureates
FEDERATION MEMBER SOCIETY NOBEL LAUREATES For achievements in Chemistry, Physiology/Medicine, and PHysics. Award Winners announced annually in October. Awards presented on December 10th, the anniversary of Nobel’s death. (-H represents Honorary member, -R represents Retired member) # YEAR AWARD NAME AND SOCIETY DOB DECEASED 1 1904 PM Ivan Petrovich Pavlov (APS-H) 09/14/1849 02/27/1936 for work on the physiology of digestion, through which knowledge on vital aspects of the subject has been transformed and enlarged. 2 1912 PM Alexis Carrel (APS/ASIP) 06/28/1873 01/05/1944 for work on vascular suture and the transplantation of blood vessels and organs 3 1919 PM Jules Bordet (AAI-H) 06/13/1870 04/06/1961 for discoveries relating to immunity 4 1920 PM August Krogh (APS-H) 11/15/1874 09/13/1949 (Schack August Steenberger Krogh) for discovery of the capillary motor regulating mechanism 5 1922 PM A. V. Hill (APS-H) 09/26/1886 06/03/1977 Sir Archibald Vivial Hill for discovery relating to the production of heat in the muscle 6 1922 PM Otto Meyerhof (ASBMB) 04/12/1884 10/07/1951 (Otto Fritz Meyerhof) for discovery of the fixed relationship between the consumption of oxygen and the metabolism of lactic acid in the muscle 7 1923 PM Frederick Grant Banting (ASPET) 11/14/1891 02/21/1941 for the discovery of insulin 8 1923 PM John J.R. Macleod (APS) 09/08/1876 03/16/1935 (John James Richard Macleod) for the discovery of insulin 9 1926 C Theodor Svedberg (ASBMB-H) 08/30/1884 02/26/1971 for work on disperse systems 10 1930 PM Karl Landsteiner (ASIP/AAI) 06/14/1868 06/26/1943 for discovery of human blood groups 11 1931 PM Otto Heinrich Warburg (ASBMB-H) 10/08/1883 08/03/1970 for discovery of the nature and mode of action of the respiratory enzyme 12 1932 PM Lord Edgar D. -
Enzyme Class 1 Download
Enzymes General Introduction MI 201 Unit:2 By: Dr. MohammedAzim Bagban Assistant Professor C. U. Shah Institute of Science Ahmedabad What is an enzyme? globular protein which functions as a biological catalyst, Active speeding up reaction site rate by lowering activation energy without being affected by the reaction it catalyse Enzymes are protein in nature (?) Globular protein. Ribozymes are RNA molecule with enzymatic activity. Catalytic behaviour of any enzyme depends upon its primary, secondary, tertiary or quaternary structure. Enzymes of digestive tract and those found in blood are present in inactive form called zymogen or proezymes. Etymology and history • French chemist Anselme Payen was the first to discover an enzyme, diastase, in 1833. • A few decades later, when studying the fermentation of sugar to alcohol by yeast, Louis Pasteur concluded that this fermentation was caused by a vital force contained within the yeast cells called "ferments", which were thought to function only within living organisms. • The conclusion that pure proteins can be enzymes was definitively demonstrated by John Howard Northrop and Wendell Meredith Stanley, who worked on the digestive enzymes pepsin (1930), trypsin and chymotrypsin. These three scientists were awarded the 1946 Nobel Prize in Chemistry. Enzyme Nomenclature . An enzyme's name is often derived from its substrate or the chemical reaction it catalyzes, with the word ending in -ase. Examples are lactase, alcohol dehydrogenase and DNA polymerase. Different enzymes that catalyze the same chemical reaction are called isozymes. The International Union of Biochemistry and Molecular Biology have developed a nomenclature for enzymes, the EC numbers; each enzyme is described by a sequence of four numbers preceded by "EC", which stands for "Enzyme Commission". -
The Beginnings of Pancreatology As a Field of Experimental and Clinical Medicine
Hindawi Publishing Corporation BioMed Research International Volume 2015, Article ID 128095, 5 pages http://dx.doi.org/10.1155/2015/128095 Review Article The Beginnings of Pancreatology as a Field of Experimental and Clinical Medicine Piotr Ceranowicz,1 Jakub Cieszkowski,1 Zygmunt Warzecha,1 Beata KuVnierz-Cabala,2 and Artur DembiNski1 1 Department of Physiology, Jagiellonian University Medical College, 16 Grzegorzecka Street, 31-531 Krakow, Poland 2Department of Diagnostics, Chair of Clinical Biochemistry, Jagiellonian University Medical College, 15 A Kopernika Street, 31-501 Krakow, Poland Correspondence should be addressed to Piotr Ceranowicz; [email protected] Received 23 March 2015; Accepted 24 April 2015 Academic Editor: Flavia Prodam Copyright © 2015 Piotr Ceranowicz et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. This review presents the history of discoveries concerning the pancreas. In antiquity and the Middle Ages knowledge aboutthe anatomy of the pancreas was very limited and its function was completely unknown. Significant progress was first made in the seventeenth and eighteenth centuries. Johann Georg Wirsung,¨ the prosector of the University of Padua, discovered the main pancreatic duct, and Giovanni Santorini discovered the accessory duct. Regnier de Graaf was the first to perform pancreatic exocrine studies, and Paul Langerhans’s 1869 discovery of pancreatic islets was the first step toward recognizing the pancreas as an endocrine gland. The twentieth century brought the discovery of insulin and other pancreatic hormones. To date, histochemical staining, transmission electron microscopy, and immunohistochemistry enabled the discovery of five cell types with identified hormonal products in adult human pancreatic islets. -
24 August 2013 Seminar Held
PROCEEDINGS OF THE NOBEL PRIZE SEMINAR 2012 (NPS 2012) 0 Organized by School of Chemistry Editor: Dr. Nabakrushna Behera Lecturer, School of Chemistry, S.U. (E-mail: [email protected]) 24 August 2013 Seminar Held Sambalpur University Jyoti Vihar-768 019 Odisha Organizing Secretary: Dr. N. K. Behera, School of Chemistry, S.U., Jyoti Vihar, 768 019, Odisha. Dr. S. C. Jamir Governor, Odisha Raj Bhawan Bhubaneswar-751 008 August 13, 2013 EMSSSEM I am glad to know that the School of Chemistry, Sambalpur University, like previous years is organizing a Seminar on "Nobel Prize" on August 24, 2013. The Nobel Prize instituted on the lines of its mentor and founder Alfred Nobel's last will to establish a series of prizes for those who confer the “greatest benefit on mankind’ is widely regarded as the most coveted international award given in recognition to excellent work done in the fields of Physics, Chemistry, Physiology or Medicine, Literature, and Peace. The Prize since its introduction in 1901 has a very impressive list of winners and each of them has their own story of success. It is heartening that a seminar is being organized annually focusing on the Nobel Prize winning work of the Nobel laureates of that particular year. The initiative is indeed laudable as it will help teachers as well as students a lot in knowing more about the works of illustrious recipients and drawing inspiration to excel and work for the betterment of mankind. I am sure the proceeding to be brought out on the occasion will be highly enlightening. -
The College of Chemistry 1948
UC Berkeley College History Title The College of Chemistry, UC Berkeley, 1948-1966 Permalink https://escholarship.org/uc/item/6g9228zg Author Myers, Rollie J. Publication Date 1990 Peer reviewed eScholarship.org Powered by the California Digital Library University of California The College of Chemistry University of California, Berkeley 1948-1966 By Professor of Chemistry Rollie J. Myers Preface Several people have asked me to put down some history about the College of Chemistry. William Jolly has already done this in great detail, but this discourse will be more of a narrative and at times more of a worm’s eye view of the college all from the viewpoint of a graduate student who arrived in 1948 and who then stayed on as a faculty member. Lewis Hall was first occupied in 1948, and by 1966 Latimer and Hildebrand Halls were finished. The Chemistry Plaza that we know today was then complete. Rollie J. Myers (1924-2016) By 1948 the College had fully recovered from G.N. Lewis’s death and from World War II. It was an important year since Lewis Hall, the first substantial College building built since Gilman Hall, was made ready for use. After Lewis stepped down in 1941, the College was first led by two of Lewis’ old associates, Wendell Latimer and Joel Hildebrand. Latimer came to Berkeley as a graduate student and as a young faculty member in 1921, and he built the first apparatus in the United States for the liquefaction of hydrogen. His interests were rather broad, and his book, “Oxidation States of the Elements and their Potentials in Aqueous Solutions”, aka Ox-Pot, was very well known. -
Le Facteur Moléculaire
Le Facteur Moléculaire Le bulletin des étudiantes et des étudiants en biochimie de Sherbrooke Automne 2010 No 5 lien Internet http://www.usherbrooke.ca/bac-biochimie/bulletin/ Distribué gratuitement aux Collèges du Québec et aux diplômé(e)s du Programme de biochimie SOMMAIRE Le baccalauréat change de nom… Enfin! Biochimie de la santé.……. 1 Pour affirmer son orientation auprès des collégiens, la nomenclature du programme change en 2010: Biochimie de la santé. Blogue…………………………… 1 Génétique des médicaments. 2 Le programme de 1er cycle en biochimie de l’UdeS recrute une Gastronomie moléculaire… 3 quarantaine de nouveaux étudiants à chaque année. Au terme de la Nobel de biochimie ………… 5 formation, les compétences singulières des finissants sont éminem- Liste des nobélisés ………….6 ment reconnues au Québec et ailleurs (Canada, USA) : des Daniel Lafontaine…………….10 connaissances étendues de la biochimie générale, de la chimie pratique, de la biologie moléculaire, de la génomique et de la No 5 génétique médicale, conjuguées à des habiletés pratiques acquises en NoNo 55 symposium, en laboratoire ou en stage (régime coopératif études- stages). Cette formation est dispensée au sein de deux facultés – Journal étudiant sciences (campus principal) et médecine/sciences de la santé (campus de la santé) – au contact de plusieurs professeurs-chercheurs œuvrant Le cinquième numéro du Facteur dans une dizaine de départements où l’enseignement et la recherche Moléculaire marque un tournant. s’orientent vers les applications biomédicales de la biochimie. Visitez le Ce Bulletin est maintenant produit par site pour mieux distinguer notre caractère unique et notre mission : les étudiantes et les étudiants en www.usherbrooke.ca/bac-biochimie/ biochimie de l’Université de Sherbrooke, de 1er, 2e et 3e cycles. -
Century Association Nobelists
CENTURY ASSOCIATION NOBELISTS INTRODUCTION In 1906, five years after the Nobel Prize was first awarded, an American finally won one: President Theodore Roosevelt captured the Peace Prize for brokering the treaty that ended the Russo-Japanese War. Long before that, the hyperactive T.R. had become one of us; he joined the Century in 1884. Remarkably, Roosevelt started what became an amazing run for Centurions. Twenty- eight others have also been named Nobel laureates, each chosen—as Swedish dynamite inventor Alfred Nobel dictated in his will—as one who “during the preceding year, shall have conferred the greatest benefit to mankind.” Centurions have won in all six prize categories, most recently in 2000. We celebrate them all in this booklet as well as in an exhibition in the President’s Room of the club (September 15–October 22, 2014). Like the city of New York, and the club membership, these Centurions are a diverse lot. Some came from wealthy, established families and were educated at the best schools and universities. Others emigrated here and climbed their way to the top. Each possessed not only a brilliant, original mind, but also the grit and the drive to rise above others in highly competitive fields and often to effect great change. Some were single-minded, totally focused on their work; others managed to pursue avocations. They all found fellowship here. These uncommon minds shared common ground at 7 West 43d Street. In 2003, New York City erected a monument honoring Alfred Nobel and all American Nobel winners in the little park, named for Roosevelt, that is adjacent to the American Museum of Natural History. -
Prix Nobel De Chimie
Physique Secondaire Prix Nobel de Chimie 1901 Jacobus Henricus van't Hoff 1902 Hermann Emil Fischer 1903 Svante August Arrhenius 1904 Sir William Ramsay 1905 Johann Friedrich Wilhelm Adolf von Baeyer 1906 Henri Moissan 1907 Eduard Buchner 1908 Ernest Rutherford 1909 Wilhelm Ostwald 1910 Otto Wallach 1911 Marie Skłodowska-Curie 1912 Victor Grignard et Paul Sabatier 1913 Alfred Werner 1914 Theodore William Richards 1915 Richard Martin Willstätter 1916 Non décerné 1917 Non décerné 1918 Fritz Haber 1919 Non décerné 1920 Walther Hermann Nernst 1921 Frederick Soddy 1922 Francis William Aston 1923 Fritz Pregl 1924 Non décerné 1925 Richard Adolf Zsigmondy 1926 Theodor Svedberg 1927 Heinrich Otto Wieland 1928 Adolf Otto Reinhold Windaus 1929 Arthur Harden et Hans Karl August Simon von Euler-Chelpin 1930 Hans Fischer 1931 Carl Bosch, Friedrich Bergius 1932 Irving Langmuir 1933 Non décerné 1934 Harold Clayton Urey 1935 Frédéric Joliot et Irène Joliot-Curie 1936 Petrus (Peter) Josephus Wilhelmus Debye 1937 Walter Norman Haworth et Paul Karrer 1938 Richard Kuhn 1939 Adolf Friedrich Johann Butenandt et Leopold Ruzicka 1940 Non décerné 1941 Non décerné 1942 Non décerné 1943 George de Hevesy 1944 Otto Hahn 1945 Artturi Ilmari Virtanen 1946 James Batcheller Sumner, John Howard Northrop et Wendell Meredith Stanley 1947 Sir Robert Robinson 1948 Arne Wilhelm Kaurin Tiselius 1949 William Francis Giauque www.physiquechimie.org Page 1 sur 3 Document Physique Secondaire 1950 Otto Paul Hermann Diels et Kurt Alder 1951 Edwin Mattison McMillan et Glenn Theodore Seaborg 1952 Archer John Porter Martin, Richard Laurence Millington Synge 1953 Hermann Staudinger 1954 Linus Carl Pauling 1955 Vincent du Vigneaud 1956 Sir Cyril Norman Hinshelwood et Nikolay Nikolaevich Semenov 1957 Lord Alexander R. -
The Development of Catalysis
Trim Size: 6.125in x 9.25in Single Columnk Zecchina ffirs.tex V2 - 02/20/2017 1:50pm Page i The Development of Catalysis k k k Trim Size: 6.125in x 9.25in Single Columnk Zecchina ffirs.tex V2 - 02/20/2017 1:50pm Page iii The Development of Catalysis A History of Key Processes and Personas in Catalytic Science and Technology Adriano Zecchina Salvatore Califano k k k Trim Size: 6.125in x 9.25in Single Columnk Zecchina ffirs.tex V2 - 02/20/2017 1:50pm Page iv Copyright © 2017 by John Wiley & Sons, Inc. All rights reserved Published by John Wiley & Sons, Inc., Hoboken, New Jersey Published simultaneously in Canada No part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, recording, scanning, or otherwise, except as permitted under Section 107 or 108 of the 1976 United States Copyright Act, without either the prior written permission of the Publisher, or authorization through payment of the appropriate per-copy fee to the Copyright Clearance Center, Inc., 222 Rosewood Drive, Danvers, MA 01923, (978) 750-8400, fax (978) 750-4470, or on the web at www.copyright.com. Requests to the Publisher for permission should be addressed to the Permissions Department, John Wiley & Sons, Inc., 111 River Street, Hoboken, NJ 07030, (201) 748-6011, fax (201) 748-6008, or online at http://www.wiley.com/go/permissions. Limit of Liability/Disclaimer of Warranty: While the publisher and author have used their best efforts in preparing this book, they make no representations or warranties with respect to the accuracy or completeness of the contents of this book and specifically disclaim any implied warranties of merchantability or fitness for a particular purpose.