DTIC) Computer- Generated Bibliography Prepared by Matching the Subject Terms: Epidemic, Coronavirus, Pandemic Against the Technical Report Database, 2020
Total Page：16
File Type：pdf, Size：1020Kb
Load more
Recommended publications
-
SIP Newsletter 2015 June V4.Pages
Society for Invertebrate Pathology Newsletter Volume 48 Issue 2 June, 2015 Downtown Vancouver at Sunset. Photo Credit: Magnus3D Meeting Events: Saturday Tuesday Registration (2 pm - 8 pm) Concurrent Sessions Sunday Excursions and 5K Race BBQ at the Cheakamus Center SIP Council Meeting OECD Satellite Symposium Wednesday Bacteria Workshop Concurrent Sessions Opening Mixer Posters Monday Division Business Meetings Founders’ Lecture Thursday Plenary Symposium Concurrent Sessions Concurrent Sessions SIP Annual & Student Business Division Business Meetings Meetings Award Ceremonies and Banquet !1 From the President Dear SIP Colleagues, This communiqué is threefold. First, I would like to encourage those of you President who have yet to do so to register for the Peter Krell, Canada 2015 SIP in Vancouver Canada, second, convince those with a flair for Vice President writing to step up to replace Eric Haas Johannes Jehle, Germany Stapleton as SIP Newsletter Editor and Past President third, inform you about our Golden Jørgen Eilenberg, Denmark Jubilee Committee. The 48th SIP meeting is just around Secretary the corner, August 9 to 13, all in the Mary Barbercheck, USA newly opened “The Nest” at the beautiful University of British Treasurer Columbia campus, overlooking the Strait of Georgia between Stefan Jaronski, USA Vancouver and Vancouver Island, and only a short bicycle ride of about 90 miles (150 km) north of Seattle. There are many reasons Trustees to attend, just check out the meeting’s website on the SIP home Surendra Dara, USA Albrecht Koppenhofer, USA page. Famous for its natural beauty with great opportunities for Ed Lewis, USA hiking, canoeing and nature photography, along with both classical Monique van Oers, The Netherlands and aboriginal culture with a mixed east/west cuisine. -
GAO-09-878R Project Bioshield Act: HHS Has Supported Development
United States Government Accountability Office Washington, DC 20548 July 24, 2009 Congressional Committees Subject: Project BioShield Act: HHS Has Supported Development, Procurement, and Emergency Use of Medical Countermeasures to Address Health Threats This report formally transmits the attached briefing in response to section 247d-6c of title 42 of the United States Code. (See the enclosure.) The statute required the Comptroller General to examine the Department of Health and Human Services’ (HHS) support for the development and procurement of and authority for the emergency use of medical countermeasures to address chemical, biological, radiological, and nuclear threats to public health, and provide the results to the congressional committees by July 21, 2009.1 HHS determines priorities for medical countermeasure procurement based on those chemical, biological, radiological, and nuclear agents that have been identified by the Department of Homeland Security as posing a material threat to the U.S. population that could affect national security. We provided the briefing to staff of your committees to satisfy the mandate reporting requirement on July 20, 2009, and July 21, 2009. – – – – – We are sending copies of this report to the Secretary of HHS, the Secretary of Homeland Security, and other interested parties. In addition, the report will be available at no charge on the GAO Web site at http://www.gao.gov. If you or your staff have any questions regarding this report, please contact me at (202) 512- 7114 or [email protected]. Contact points for our Offices of Congressional Relations and Public Affairs may be found on the last page of this report. -
Necessary Fictions”: Authorship and Transethnic Identity in Contemporary American Narratives
MILNE, LEAH A., PhD. “Necessary Fictions”: Authorship and Transethnic Identity in Contemporary American Narratives. (2015) Directed by Dr. Christian Moraru. 352 pp. As a theory and political movement of the late 20th century, multiculturalism has emphasized recognition, tolerance, and the peaceful coexistence of cultures, while providing the groundwork for social justice and the expansion of the American literary canon. However, its sometimes uncomplicated celebrations of diversity and its focus on static, discrete ethnic identities have been seen by many as restrictive. As my project argues, contemporary ethnic American novelists are pushing against these restrictions by promoting what I call transethnicity, the process by which one formulates a dynamic conception of ethnicity that cuts across different categories of identity. Through the use of self-conscious or metafictional narratives, authors such as Louise Erdrich, Junot Díaz, and Percival Everett mobilize metafiction to expand definitions of ethnicity and to acknowledge those who have been left out of the multicultural picture. I further argue that, while metafiction is often considered the realm of white male novelists, ethnic American authors have galvanized self-conscious fiction—particularly stories depicting characters in the act of writing—to defy multiculturalism’s embrace of coherent, reducible ethnic groups who are best represented by their most exceptional members and by writing that is itself correct and “authentic.” Instead, under the transethnic model, ethnicity is self-conflicted, forged through ongoing revision and contestation and in ever- fluid responses to political, economic, and social changes. “NECESSARY FICTIONS”: AUTHORSHIP AND TRANSETHNIC IDENTITY IN CONTEMPORARY AMERICAN NARRATIVES by Leah A. Milne A Dissertation Submitted to the Faculty of The Graduate School at The University of North Carolina at Greensboro in Partial Fulfillment of the Requirements for the Degree Doctor of Philosophy Greensboro 2015 Approved by _____________________ Committee Chair ©2015 Leah A. -
Medical Management of Biological Casualties Handbook
USAMRIID’s MEDICAL MANAGEMENT OF BIOLOGICAL CASUALTIES HANDBOOK Sixth Edition April 2005 U.S. ARMY MEDICAL RESEARCH INSTITUTE OF INFECTIOUS DISEASES FORT DETRICK FREDERICK, MARYLAND Emergency Response Numbers National Response Center: 1-800-424-8802 or (for chem/bio hazards & terrorist events) 1-202-267-2675 National Domestic Preparedness Office: 1-202-324-9025 (for civilian use) Domestic Preparedness Chem/Bio Helpline: 1-410-436-4484 or (Edgewood Ops Center – for military use) DSN 584-4484 USAMRIID’s Emergency Response Line: 1-888-872-7443 CDC'S Emergency Response Line: 1-770-488-7100 Handbook Download Site An Adobe Acrobat Reader (pdf file) version of this handbook can be downloaded from the internet at the following url: http://www.usamriid.army.mil USAMRIID’s MEDICAL MANAGEMENT OF BIOLOGICAL CASUALTIES HANDBOOK Sixth Edition April 2005 Lead Editor Lt Col Jon B. Woods, MC, USAF Contributing Editors CAPT Robert G. Darling, MC, USN LTC Zygmunt F. Dembek, MS, USAR Lt Col Bridget K. Carr, MSC, USAF COL Ted J. Cieslak, MC, USA LCDR James V. Lawler, MC, USN MAJ Anthony C. Littrell, MC, USA LTC Mark G. Kortepeter, MC, USA LTC Nelson W. Rebert, MS, USA LTC Scott A. Stanek, MC, USA COL James W. Martin, MC, USA Comments and suggestions are appreciated and should be addressed to: Operational Medicine Department Attn: MCMR-UIM-O U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID) Fort Detrick, Maryland 21702-5011 PREFACE TO THE SIXTH EDITION The Medical Management of Biological Casualties Handbook, which has become affectionately known as the "Blue Book," has been enormously successful - far beyond our expectations. -
Fort Detrick, Frederick, MD
Fort Detrick, Frederick, MD FACT SHEET as of February 2018 Background: Fort Detrick encompasses approximately 1,200 acres divided among three areas in Frederick, Md. Area A is the largest, comprised of approximately 800 acres, and the primary area of construction activity. Most of the Fort Detrick facilities, tenants, post housing, and community facilities are located in Area A. The Forest Glen Annex, Silver Spring, Md., also falls under the operational control of Fort Detrick. The current Corps of Engineers design/construction program on Fort Detrick is approximately $724 million, featuring the $678-million U.S. Army Institute of Infectious Diseases (USAMRIID) Replacement project, the only Department of Defense high-containment biological laboratory. Fort Detrick, originally named Camp Detrick until 1956, was established in 1931 as a military training airfield named after Maj. Frederick Detrick, a squadron surgeon. In 1943, the U.S. Biological Laboratories were established, pioneering efforts in decontamination, gaseous sterilization and agent purification. In 1969, Fort Detrick’s biological warfare research center mission was terminated and 69 acres of the installation were transferred to the Department of Health and Human Services to conduct cancer research. The installation has now matured into a multi-interagency campus (four cabinet level tenants) focusing on advanced bio-medical research and development, medical materiel management, and long-haul telecommunications for the White House, Department of Defense, and other governmental agencies. The National Interagency Biodefense Campus (NIBC) is currently the focal point of all activities on the installation, and the new USAMRIID project is the cornerstone of the campus. Names and phone numbers for significant installation points of contact are as follows: Congressional Rep (D-6th) John Delaney Congressional Rep (D-8th) Jamie Raskin Installation/MRMC Commander MG Barbara R. -
Gene Gain and Loss Events in Rickettsia and Orientia Species Kalliopi Georgiades1,2, Vicky Merhej1, Khalid El Karkouri1, Didier Raoult1, Pierre Pontarotti2*
Georgiades et al. Biology Direct 2011, 6:6 http://www.biology-direct.com/content/6/1/6 RESEARCH Open Access Gene gain and loss events in Rickettsia and Orientia species Kalliopi Georgiades1,2, Vicky Merhej1, Khalid El Karkouri1, Didier Raoult1, Pierre Pontarotti2* Abstract Background: Genome degradation is an ongoing process in all members of the Rickettsiales order, which makes these bacterial species an excellent model for studying reductive evolution through interspecies variation in genome size and gene content. In this study, we evaluated the degree to which gene loss shaped the content of some Rickettsiales genomes. We shed light on the role played by horizontal gene transfers in the genome evolution of Rickettsiales. Results: Our phylogenomic tree, based on whole-genome content, presented a topology distinct from that of the whole core gene concatenated phylogenetic tree, suggesting that the gene repertoires involved have different evolutionary histories. Indeed, we present evidence for 3 possible horizontal gene transfer events from various organisms to Orientia and 6 to Rickettsia spp., while we also identified 3 possible horizontal gene transfer events from Rickettsia and Orientia to other bacteria. We found 17 putative genes in Rickettsia spp. that are probably the result of de novo gene creation; 2 of these genes appear to be functional. On the basis of these results, we were able to reconstruct the gene repertoires of “proto-Rickettsiales” and “proto-Rickettsiaceae”, which correspond to the ancestors of Rickettsiales and Rickettsiaceae, respectively. Finally, we found that 2,135 genes were lost during the evolution of the Rickettsiaceae to an intracellular lifestyle. Conclusions: Our phylogenetic analysis allowed us to track the gene gain and loss events occurring in bacterial genomes during their evolution from a free-living to an intracellular lifestyle. -
Scrub Typhus and Molecular Characterization of Orientia Tsutsugamushi from Central Nepal
pathogens Article Scrub Typhus and Molecular Characterization of Orientia tsutsugamushi from Central Nepal Rajendra Gautam 1, Keshab Parajuli 1, Mythili Tadepalli 2, Stephen Graves 2, John Stenos 2,* and Jeevan Bahadur Sherchand 1 1 Department of Microbiology, Maharajgunj Medical Campus, Institute of Medicine, Kathmandu 44600, Nepal; [email protected] (R.G.); [email protected] (K.P.); [email protected] (J.B.S.) 2 Australian Rickettsial Reference Laboratory, Geelong, VIC 3220, Australia; [email protected] (M.T.); [email protected] (S.G.) * Correspondence: [email protected]; Tel.: +61-342151357 Abstract: Scrub typhus is a vector-borne, acute febrile illness caused by Orientia tsutsugamushi. Scrub typhus continues to be an important but neglected tropical disease in Nepal. Information on this pathogen in Nepal is limited to serological surveys with little information available on molecular methods to detect O. tsutsugamushi. Limited information exists on the genetic diversity of this pathogen. A total of 282 blood samples were obtained from patients with suspected scrub typhus from central Nepal and 84 (30%) were positive for O. tsutsugamushi by 16S rRNA qPCR. Positive samples were further subjected to 56 kDa and 47 kDa molecular typing and molecularly compared to other O. tsutsugamushi strains. Phylogenetic analysis revealed that Nepalese O. tsutsugamushi strains largely cluster together and cluster away from other O. tsutsugamushi strains from Asia and elsewhere. One exception was the sample of Nepal_1, with its partial 56 kDa sequence clustering Citation: Gautam, R.; Parajuli, K.; more closely with non-Nepalese O. tsutsugamushi 56 kDa sequences, potentially indicating that Tadepalli, M.; Graves, S.; Stenos, J.; homologous recombination may influence the genetic diversity of strains in this region. -
Nov03 POSTER1106.Indd
The National Cancer Institute Ft. Detrick’s 60th Anniversary story on page 3. News from the NCI-Frederick NOVEMBER 2003 Offi ce of Scientifi c Operations IN THIS ISSUE This year we celebrate the 60th Owned-Contractor Operated (GOCO) Ft. Detrick’s 60th Anniversary 3 anniversary of Fort (Ft.) Detrick. facility. Ft. Detrick’s roots can be traced to The fi rst employees of the NCI- Major Construction Projects 4 a small municipal airport known as Frederick (then known as the Detrick Field1, The Field was named Frederick Cancer Research Center) Building 470 Update 5 to honor Major Frederick L. Detrick, appeared on campus in June 1972 and who served in France during World numbered around 20 by the end of Scientifi c Publications, War I. The fi rst military presence at that month. By 1976 these numbers Graphics & Media News 6 the airfi eld was in 1931 when the had grown to about 750 individuals, Maryland National Guard established and by 1987 the staff numbered over Awards 6 a cadet pilot training center at Detrick 1,400 with a budget of nearly $100 Field and subsequently Platinum Publications 8 changed the name to Camp Detrick. Poster-Script 11 As we pause to think about the history of Ft. Did You Know? 12 Detrick and the many contributions that the Transfer Technology Branch 14 staff of Ft. Detrick has made in the areas of Community Outreach 15 infectious disease and national defense, it Offi ce of Diversity and seems that now is an Employee Programs 16 appropriate time to also look back at the history Environment, Health, and Safety of the NCI here at Ft. -
Scientific Program Table of Contents
Scientific Program Table of Contents Scheduling and locations are subject to change without notice. Please check the onsite newsletter each morning for changes Sunday, July 15 SYMPOSIA AND ORAL SESSIONS ASN-ADSA-ASAS Preconference: Regulation of Nutritional Intake and Metabolism ................................................................49 Triennial Reproduction Symposium: Impediments to Fertility in Domestic Animals ...............................................................49 Monday, July 16 POSTER PRESENTATIONS Animal Health I ...................................................................................................................................................................................................51 Breeding and Genetics: Fertility and Early-Life Traits ............................................................................................................................52 Companion Animals .........................................................................................................................................................................................53 Dairy Foods ..........................................................................................................................................................................................................54 Forages and Pastures I ......................................................................................................................................................................................55 Graduate -
Persistence of Orientia Tsutsugamushiin Humans
ORIGINAL ARTICLE Infectious Diseases, Microbiology & Parasitology http://dx.doi.org/10.3346/jkms.2012.27.3.231 • J Korean Med Sci 2012; 27: 231-235 Persistence of Orientia tsutsugamushi in Humans Moon-Hyun Chung1, Jin-Soo Lee1, We investigated the persistence of viable Orientia tsutsugamushi in patients who had Ji-hyeon Baek1, Mijeong Kim1, recovered from scrub typhus. Blood specimens were available from six patients with scrub and Jae-Seung Kang2 typhus who were at 1 to 18 months after the onset of the illness. The EDTA-treated blood specimens were inoculated into ECV304 cells, and cultures were maintained for 7 months. 1Departments of Internal Medicine, and 2Microbiology, Inha University School of Sequencing of the 56-kDa type-specific antigen gene ofO. tsutsugamushi was performed Medicine, Incheon, Korea to ascertain the homology of isolates. O. tsutsugamushi was isolated from all six patients, and nucleotide sequences of isolates serially collected from each patient were identical in Received: 9 October 2011 all five patients in whom nucleotide sequences were compared. One patient relapsed 2 Accepted: 3 January 2012 days after completion of antibiotic therapy; two patients complained of weakness for 1 to Address for Correspondence: 2.5 months after the illness; one patient underwent coronary angioplasty 6 months later; Jae-Seung Kang, MD and one patient suffered from a transient ischemic attack 8 months later. This finding Department of Microbiology, Inha University School of Medicine, 27 Inhang-ro, Jung-gu, Incheon 400-712, Korea suggests that O. tsutsugamushi causes chronic latent infection, which may be associated Tel: +82.32-890-0952, Fax: +82.32-881-8559 with certain clinical illnesses, preceded by scrub typhus. -
Bioterrorism, Biological Weapons and Anthrax
Bioterrorism, Biological Weapons and Anthrax Part IV Written by Arthur H. Garrison Criminal Justice Planning Coordinator Delaware Criminal Justice Council Bioterrorism and biological weapons The use of bio-terrorism and bio-warfare dates back to 6th century when the Assyrians poisoned the well water of their enemies. The goal of using biological weapons is to cause massive sickness or death in the intended target. Bioterrorism and biological weapons The U.S. took the threat of biological weapons attack seriously after Gulf War. Anthrax vaccinations of U.S. troops Investigating Iraq and its biological weapons capacity The Soviet Union manufactured various types of biological weapons during the 1980’s • To be used after a nuclear exchange • Manufacturing new biological weapons – Gene engineering – creating new types of viruses/bacteria • Contagious viruses – Ebola, Marburg (Filoviruses) - Hemorrhagic fever diseases (vascular system dissolves) – Smallpox The spread of biological weapons after the fall of the Soviet Union •Material • Knowledge and expertise •Equipment Bioterrorism and biological weapons There are two basic categories of biological warfare agents. Microorganisms • living organic germs, such as anthrax (bacillus anthrax). –Bacteria –Viruses Toxins • By-products of living organisms (natural poisons) such as botulism (botulinum toxin) which is a by- product of growing the microorganism clostridium botulinum Bioterrorism and biological weapons The U.S. was a leader in the early research on biological weapons Research on making -
Identification of Trombiculid Chigger Mites Collected on Rodents from Southern Vietnam and Molecular Detection of Rickettsiaceae Pathogen
ISSN (Print) 0023-4001 ISSN (Online) 1738-0006 Korean J Parasitol Vol. 58, No. 4: 445-450, August 2020 ▣ ORIGINAL ARTICLE https://doi.org/10.3347/kjp.2020.58.4.445 Identification of Trombiculid Chigger Mites Collected on Rodents from Southern Vietnam and Molecular Detection of Rickettsiaceae Pathogen 1, 2, 1 3 4,5, 4,5, Minh Doan Binh †, Sinh Cao Truong †, Dong Le Thanh , Loi Cao Ba , Nam Le Van * , Binh Do Nhu * 1Ho Chi Minh Institute of Malariology-Parasitology and Entomology, Ho Chi Minh Vietnam; 2Vinh Medical University, Nghe An, Vietnam; 3National Institute of Malariology-Parasitology and Entomology, Ha Noi, Vietnam; 4Military Hospital 103, Ha Noi, Vietnam; 5Vietnam Military Medical University, Ha Noi, Vietnam Abstract: Trombiculid “chigger” mites (Acari) are ectoparasites that feed blood on rodents and another animals. A cross- sectional survey was conducted in 7 ecosystems of southern Vietnam from 2015 to 2016. Chigger mites were identified with morphological characteristics and assayed by polymerase chain reaction for detection of rickettsiaceae. Overall chigger infestation among rodents was 23.38%. The chigger index among infested rodents was 19.37 and a mean abun- dance of 4.61. A total of 2,770 chigger mites were identified belonging to 6 species, 3 genera, and 1 family, and pooled into 141 pools (10-20 chiggers per pool). Two pools (1.4%) of the chiggers were positive for Orientia tsutsugamushi. Rick- etsia spp. was not detected in any pools of chiggers. Further studies are needed including a larger number and diverse hosts, and environmental factors to assess scrub typhus. Key words: Oriental tsutsugamushi, Rickettsia sp., chigger mite, ectoparasite INTRODUCTION Orientia tsutsugamushi is a gram-negative bacteria and caus- ative agent of scrub typhus, is a vector-borne zoonotic disease Trombiculid mites (Acari: Trombiculidae) are ectoparasites with the potential of causing life-threatening febrile infection that are found in grasses and herbaceous vegetation.