DOCSLIB.ORG

DTIC) Computer- Generated Bibliography Prepared by Matching the Subject Terms: Epidemic, Coronavirus, Pandemic Against the Technical Report Database, 2020

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
DTIC) Computer- Generated Bibliography Prepared by Matching the Subject Terms: Epidemic, Coronavirus, Pandemic Against the Technical Report Database, 2020 Description of document: Defense Technical Information Center (DTIC) computer- generated bibliography prepared by matching the subject terms: epidemic, coronavirus, pandemic against the Technical Report database, 2020 Requested date: 12-April-2020 Release date: 19-May-2020 Posted date: 01-June-2020 Source of document: Defense Technical Information Center (DTIC-R) ATTN: FOIA Requester Service Center 8725 John J. Kingman Road Fort Belvoir, Virginia 22060-6218 Fax: 703-767-9201 Email Form Contact DTIC FOIA The governmentattic.org web site (“the site”) is a First Amendment free speech web site, and is noncommercial and free to the public. The site and materials made available on the site, such as this file, are for reference only. The governmentattic.org web site and its principals have made every effort to make this information as complete and as accurate as possible, however, there may be mistakes and omissions, both typographical and in content. The governmentattic.org web site and its principals shall have neither liability nor responsibility to any person or entity with respect to any loss or damage caused, or alleged to have been caused, directly or indirectly, by the information provided on the governmentattic.org web site or in this file. The public records published on the site were obtained from government agencies using proper legal channels. Each document is identified as to the source. Any concerns about the contents of the site should be directed to the agency originating the document in question. GovernmentAttic.org is not responsible for the contents of documents published on the website. DEFENSE TECHNICAL INFORMATION CENTER 8725 JOHN J. KINGMAN ROAD FORT BELVOIR, VIRGINIA 22060-6218 ~~::~1 DTIC-R (FOIA 2020-77) May 19, 2020 This is in response to your email dated April 12, 2020, received in this office April 13, 2020, requesting information under the Freedom of Information Act (FOIA) ( enclosure 1). Under Department of Defense rules implementing the FOIA, published at 32 CFR 286, your request was categorized as "other". Enclosure 2 is a computer-generated bibliography prepared by matching the subject terms in your request against our Technical Report database. The bibliography may contain some documents that do not apply to the specific subject areas in which you are interested; however, to eliminate any of the key search terms could also eliminate documents that do apply to your subject area(s) of interest. Enclosure 3 consists of a bibliography that contains unclassified descriptions of classified and/or unclassified/limited distribution documents related to your request. These documents may only be released by the controlling activity. Requests for these documents should be forwarded to the controlling activity, usually identified in the Distribution Statement field of the citation. This office upon request can research documents with no controlling activity identified to determine the appropriate owning agency. NOTE: Although some of the citations listed on the bibliography at attachment 2 may indicate that the document can be viewed and/or downloaded in full text, be advised that these citations/documents are not available to the general public through the DTIC Online Public Technical Reports database. To date, there are no assessable fees for services from DTIC. Please understand that other members of the public may submit a FOIA request for copies of FOIA requests received by this office, or the names of those who have submitted requests. Should such occur, your name and, if asked for, a copy of your request will be released; however, your home address and home telephone number will not be released. Other private citizens who have obtained your name by using such a request may contact you; however, DTIC-R (FOIA 2020-77) Page 2 correspondence from the DoD about your request will be on official letterhead. Please contact me at (571) 448-9702 if you have any questions. Thank you for your interest in obtaining information from DTIC. Sincerely, 3 Enclosures Michael Hamilton FOIA Program Manager Unclassified citations to Classified documents Highest Classification: Unclassified Search: (epidemic OR coronavirus OR pandemic) Accession Report Distribution Title Corporate Author Personal Authors Report Date Pagination Report Numbers Monitor Series Distribution Statement Descriptive Note Number" Classification Codes ADC076414" The Navy CM Mission, CENTER FOR NAVAL Savitz, Scott,Speers, 5/1/2008 112 CIM- CNO/AD S E - 04 Distribution authorized to Not available Installation CBRNE ANALYSES ALEXANDRIA Rosemary,Hughes, D0015379.A4-REV- DoD only; Specific Preparedness, and Joint VA Christine,Dickey, 1 Authority; MAY 2008. Program Guardian IPP. Brad,Grund, Matthew R. Other requests shall be Appendices referred to Office of the Chief of Naval Operations, Assessment Div. (N81B), Washington, DC 20350. AD0377138" LABORATORY EVALUATION FORT DETRICK FREDERICK Beck, Earl S.,Miller, Helen 10/1/1966 47 TS-52 ABL/MD C C - 02 Distribution authorized to TECHNICAL STUDY OF O'NYONG-NYONG FEVER MD V.,Hearn, Jr, Henry J. U.S. Gov't. agencies and their contractors; Administrative/Operation al Use; OCT 1966. Other requests shall be referred to Army Biological Laboratory, Attn: Technical Releases Branch, Technical Information Div., Fort Detrick, Frederick, MD 21701. ADC004340" An Evaluation of the Implicit NAVAL RADIOLOGICAL Alderson,D. M.,Spotts,R. 4/26/1967 100 USNRDL-TR-67-43 Not available C C - 09 Distribution authorized to Not available Risk of Sole-Source DEFENSE LAB SAN L.,Freund,D.,Hesser,R. U.S. Gov't. agencies and Procurement of the DX/DXG FRANCISCO CALIF L.,Sullivan,M. A. their contractors; in the Event of National or Administrative/Operation Local Disaster, al Use; APR 196. Other requests shall be referred to NAVAL RADIOLOGICAL DEFENSE LAB SAN FRANCISCO CALIF Highest Classification: Unclassified Page 1 of 1 Pages Unclassified/Limited Distribution Highest Classification: Unclassified Search: (epidemic OR coronavirus OR pandemic) Accession Report Distribution Title Corporate Author Personal Authors Report Date Pagination Report Numbers Monitor Series Distribution Statement Descriptive Note Number" Classification Codes AD0852697" Quarterly Report Number 3- NATIONAL Brachman, Philip S. 4/1/1969 31 Not available ABL/MD U C - 02 Distribution authorized to Rept. for 1 Jan-31 Mar 1969 FY 1969 COMMUNICABLE U.S. Gov't. agencies and DISEASE CENTER their contractors; ATLANTA GA Administrative/Operational Use; APR 1969. Other requests shall be referred to Commanding Officer, Fort Detrick, Attn: Technical Releases Branch. Frederick, MD 21701., Availability: Document partially illegible. AD0874390" Etiology of Acute Respiratory CALIFORNIA STATE DEPT Lennette,Edwin 8/15/1970 19 Not available Not available U E - 04 Distribution: DoD only: Annual rept. 1 Oct 69-31 Diseases. OF PUBLIC HEALTH H.,Schieble,Jack others to Commanding May 70, BERKELEY VIRAL AND H.,Magoffin,Robert L. General, Army Medical RICKETTSIAL DISEASE Research and Development LAB Command, Attn: MEDDH-SI. Washington, D. C. 20314. ADB340157" A Point-of-Care Assay for the INBIOS INTERNATIONAL Morrow, W. J. 5/17/2008 24 Not available USAMRMC U B - 03 Distribution authorized to Final rept. 18 Oct 2007-17 Detection of Spotted Fever INC SEATTLE WA U.S. Gov't. agencies only; Apr 2008 Group and Typhus Group Proprietary Information; Rickettsia MAY 2008. Other requests shall be referred to US Army Medical and Materiel Command, 504 Scott Street, Ft. Detrick, MD 21702-5012. Page 1 of 95 Pages Unclassified/Limited Distribution ADB356993" Theory of Epidemic Spreading CERTUS LLC WEST UNIV Deem, Michael W. 2/22/2010 30 Not available DARPA/DSO U B - 03 Distribution authorized to Final rept. Jul 2009-Feb 2010 and Topological Data Analysis PLACE TX U.S. Gov't. agencies only; of the H1N1 (novel) Pandemic Critical Technology; Premature Dissemination; Proprietary Information; FEB 2010. Other requests shall be referred to Defense Advanced Research Projects Agency, Defense Science Office, 3701 North Fairfax Dr., Arlington, VA 22203- 1714. This document contains export-controlled technical data. AD0819597" GENETIC RELATIONSHIPS CALIFORNIA UNIV LOS Rasmussen,A. Frederick , 8/1/1967 79 Not available Not available U E - 04 Distribution: DoD only: Annual progress rept. 1 Nov AMONG HUMAN AND ANGELES Jr others to Commanding 66-30 Jun 67 and final rept. 1 ANIMAL STRAINS OF General, Army Medical Sep 63-30 Jun 67, INFLUENZA VIRUS. Research and Development Command, Attn: MEDDHSI. Washington, D. C. 20315. ADB330155" Medical Vanguard Disease GEORGETOWN UNIV Mun, Seong K. 10/1/2006 99 Not available USAMRMC U B - 03 Distribution authorized to Final rept. Surveillance Phase IV: West WASHINGTON DC U.S. Gov't. agencies only; Nile Virus Phase 3 Proprietary Information; AUG 2005. Other requests shall be referred to U.S. Army Medical Research and Materiel Command, 504 Scott Street, Fort Detrick, MD 21702-5012. ADB337499" Review of Pandemic Influenza CENTER FOR NAVAL Speers, 2/1/2008 75 CRM- SF(C6F) U E - 04 Distribution authorized to Final rept. Planning and Coordination ANALYSES ALEXANDRIA Rosemary,Stewart, D0017584.A2 DoD only; Specific Authority; Requirements for CNE-C6F VA Jessica,Grund, Matthew FEB 2008. Other requests shall be referred to Navy Europe Plans and Operations, PSC 817, Box 70, FPO, AE 09622-0002. Page 2 of 95 Pages Unclassified/Limited Distribution ADB137089" Epidemiological ARMED FORCES Drndarevic, 10/16/1989 10 AFMIC-HT-087-89 Not available U B - 03 Distribution authorized to Not available Characteristics
Load more

Recommended publications
  • SIP Newsletter 2015 June V4.Pages
    Society for Invertebrate Pathology Newsletter Volume 48 Issue 2 June, 2015 Downtown Vancouver at Sunset. Photo Credit: Magnus3D Meeting Events: Saturday Tuesday Registration (2 pm - 8 pm) Concurrent Sessions Sunday Excursions and 5K Race BBQ at the Cheakamus Center SIP Council Meeting OECD Satellite Symposium Wednesday Bacteria Workshop Concurrent Sessions Opening Mixer Posters Monday Division Business Meetings Founders’ Lecture Thursday Plenary Symposium Concurrent Sessions Concurrent Sessions SIP Annual & Student Business Division Business Meetings Meetings Award Ceremonies and Banquet !1 From the President Dear SIP Colleagues, This communiqué is threefold. First, I would like to encourage those of you President who have yet to do so to register for the Peter Krell, Canada 2015 SIP in Vancouver Canada, second, convince those with a flair for Vice President writing to step up to replace Eric Haas Johannes Jehle, Germany Stapleton as SIP Newsletter Editor and Past President third, inform you about our Golden Jørgen Eilenberg, Denmark Jubilee Committee. The 48th SIP meeting is just around Secretary the corner, August 9 to 13, all in the Mary Barbercheck, USA newly opened “The Nest” at the beautiful University of British Treasurer Columbia campus, overlooking the Strait of Georgia between Stefan Jaronski, USA Vancouver and Vancouver Island, and only a short bicycle ride of about 90 miles (150 km) north of Seattle. There are many reasons Trustees to attend, just check out the meeting’s website on the SIP home Surendra Dara, USA Albrecht Koppenhofer, USA page. Famous for its natural beauty with great opportunities for Ed Lewis, USA hiking, canoeing and nature photography, along with both classical Monique van Oers, The Netherlands and aboriginal culture with a mixed east/west cuisine.
    [Show full text]
  • GAO-09-878R Project Bioshield Act: HHS Has Supported Development
    United States Government Accountability Office Washington, DC 20548 July 24, 2009 Congressional Committees Subject: Project BioShield Act: HHS Has Supported Development, Procurement, and Emergency Use of Medical Countermeasures to Address Health Threats This report formally transmits the attached briefing in response to section 247d-6c of title 42 of the United States Code. (See the enclosure.) The statute required the Comptroller General to examine the Department of Health and Human Services’ (HHS) support for the development and procurement of and authority for the emergency use of medical countermeasures to address chemical, biological, radiological, and nuclear threats to public health, and provide the results to the congressional committees by July 21, 2009.1 HHS determines priorities for medical countermeasure procurement based on those chemical, biological, radiological, and nuclear agents that have been identified by the Department of Homeland Security as posing a material threat to the U.S. population that could affect national security. We provided the briefing to staff of your committees to satisfy the mandate reporting requirement on July 20, 2009, and July 21, 2009. – – – – – We are sending copies of this report to the Secretary of HHS, the Secretary of Homeland Security, and other interested parties. In addition, the report will be available at no charge on the GAO Web site at http://www.gao.gov. If you or your staff have any questions regarding this report, please contact me at (202) 512- 7114 or [email protected]. Contact points for our Offices of Congressional Relations and Public Affairs may be found on the last page of this report.
    [Show full text]
  • Necessary Fictions”: Authorship and Transethnic Identity in Contemporary American Narratives
    MILNE, LEAH A., PhD. “Necessary Fictions”: Authorship and Transethnic Identity in Contemporary American Narratives. (2015) Directed by Dr. Christian Moraru. 352 pp. As a theory and political movement of the late 20th century, multiculturalism has emphasized recognition, tolerance, and the peaceful coexistence of cultures, while providing the groundwork for social justice and the expansion of the American literary canon. However, its sometimes uncomplicated celebrations of diversity and its focus on static, discrete ethnic identities have been seen by many as restrictive. As my project argues, contemporary ethnic American novelists are pushing against these restrictions by promoting what I call transethnicity, the process by which one formulates a dynamic conception of ethnicity that cuts across different categories of identity. Through the use of self-conscious or metafictional narratives, authors such as Louise Erdrich, Junot Díaz, and Percival Everett mobilize metafiction to expand definitions of ethnicity and to acknowledge those who have been left out of the multicultural picture. I further argue that, while metafiction is often considered the realm of white male novelists, ethnic American authors have galvanized self-conscious fiction—particularly stories depicting characters in the act of writing—to defy multiculturalism’s embrace of coherent, reducible ethnic groups who are best represented by their most exceptional members and by writing that is itself correct and “authentic.” Instead, under the transethnic model, ethnicity is self-conflicted, forged through ongoing revision and contestation and in ever- fluid responses to political, economic, and social changes. “NECESSARY FICTIONS”: AUTHORSHIP AND TRANSETHNIC IDENTITY IN CONTEMPORARY AMERICAN NARRATIVES by Leah A. Milne A Dissertation Submitted to the Faculty of The Graduate School at The University of North Carolina at Greensboro in Partial Fulfillment of the Requirements for the Degree Doctor of Philosophy Greensboro 2015 Approved by _____________________ Committee Chair ©2015 Leah A.
    [Show full text]
  • Medical Management of Biological Casualties Handbook
    USAMRIID’s MEDICAL MANAGEMENT OF BIOLOGICAL CASUALTIES HANDBOOK Sixth Edition April 2005 U.S. ARMY MEDICAL RESEARCH INSTITUTE OF INFECTIOUS DISEASES FORT DETRICK FREDERICK, MARYLAND Emergency Response Numbers National Response Center: 1-800-424-8802 or (for chem/bio hazards & terrorist events) 1-202-267-2675 National Domestic Preparedness Office: 1-202-324-9025 (for civilian use) Domestic Preparedness Chem/Bio Helpline: 1-410-436-4484 or (Edgewood Ops Center – for military use) DSN 584-4484 USAMRIID’s Emergency Response Line: 1-888-872-7443 CDC'S Emergency Response Line: 1-770-488-7100 Handbook Download Site An Adobe Acrobat Reader (pdf file) version of this handbook can be downloaded from the internet at the following url: http://www.usamriid.army.mil USAMRIID’s MEDICAL MANAGEMENT OF BIOLOGICAL CASUALTIES HANDBOOK Sixth Edition April 2005 Lead Editor Lt Col Jon B. Woods, MC, USAF Contributing Editors CAPT Robert G. Darling, MC, USN LTC Zygmunt F. Dembek, MS, USAR Lt Col Bridget K. Carr, MSC, USAF COL Ted J. Cieslak, MC, USA LCDR James V. Lawler, MC, USN MAJ Anthony C. Littrell, MC, USA LTC Mark G. Kortepeter, MC, USA LTC Nelson W. Rebert, MS, USA LTC Scott A. Stanek, MC, USA COL James W. Martin, MC, USA Comments and suggestions are appreciated and should be addressed to: Operational Medicine Department Attn: MCMR-UIM-O U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID) Fort Detrick, Maryland 21702-5011 PREFACE TO THE SIXTH EDITION The Medical Management of Biological Casualties Handbook, which has become affectionately known as the "Blue Book," has been enormously successful - far beyond our expectations.
    [Show full text]
  • Fort Detrick, Frederick, MD
    Fort Detrick, Frederick, MD FACT SHEET as of February 2018 Background: Fort Detrick encompasses approximately 1,200 acres divided among three areas in Frederick, Md. Area A is the largest, comprised of approximately 800 acres, and the primary area of construction activity. Most of the Fort Detrick facilities, tenants, post housing, and community facilities are located in Area A. The Forest Glen Annex, Silver Spring, Md., also falls under the operational control of Fort Detrick. The current Corps of Engineers design/construction program on Fort Detrick is approximately $724 million, featuring the $678-million U.S. Army Institute of Infectious Diseases (USAMRIID) Replacement project, the only Department of Defense high-containment biological laboratory. Fort Detrick, originally named Camp Detrick until 1956, was established in 1931 as a military training airfield named after Maj. Frederick Detrick, a squadron surgeon. In 1943, the U.S. Biological Laboratories were established, pioneering efforts in decontamination, gaseous sterilization and agent purification. In 1969, Fort Detrick’s biological warfare research center mission was terminated and 69 acres of the installation were transferred to the Department of Health and Human Services to conduct cancer research. The installation has now matured into a multi-interagency campus (four cabinet level tenants) focusing on advanced bio-medical research and development, medical materiel management, and long-haul telecommunications for the White House, Department of Defense, and other governmental agencies. The National Interagency Biodefense Campus (NIBC) is currently the focal point of all activities on the installation, and the new USAMRIID project is the cornerstone of the campus. Names and phone numbers for significant installation points of contact are as follows: Congressional Rep (D-6th) John Delaney Congressional Rep (D-8th) Jamie Raskin Installation/MRMC Commander MG Barbara R.
    [Show full text]
  • Gene Gain and Loss Events in Rickettsia and Orientia Species Kalliopi Georgiades1,2, Vicky Merhej1, Khalid El Karkouri1, Didier Raoult1, Pierre Pontarotti2*
    Georgiades et al. Biology Direct 2011, 6:6 http://www.biology-direct.com/content/6/1/6 RESEARCH Open Access Gene gain and loss events in Rickettsia and Orientia species Kalliopi Georgiades1,2, Vicky Merhej1, Khalid El Karkouri1, Didier Raoult1, Pierre Pontarotti2* Abstract Background: Genome degradation is an ongoing process in all members of the Rickettsiales order, which makes these bacterial species an excellent model for studying reductive evolution through interspecies variation in genome size and gene content. In this study, we evaluated the degree to which gene loss shaped the content of some Rickettsiales genomes. We shed light on the role played by horizontal gene transfers in the genome evolution of Rickettsiales. Results: Our phylogenomic tree, based on whole-genome content, presented a topology distinct from that of the whole core gene concatenated phylogenetic tree, suggesting that the gene repertoires involved have different evolutionary histories. Indeed, we present evidence for 3 possible horizontal gene transfer events from various organisms to Orientia and 6 to Rickettsia spp., while we also identified 3 possible horizontal gene transfer events from Rickettsia and Orientia to other bacteria. We found 17 putative genes in Rickettsia spp. that are probably the result of de novo gene creation; 2 of these genes appear to be functional. On the basis of these results, we were able to reconstruct the gene repertoires of “proto-Rickettsiales” and “proto-Rickettsiaceae”, which correspond to the ancestors of Rickettsiales and Rickettsiaceae, respectively. Finally, we found that 2,135 genes were lost during the evolution of the Rickettsiaceae to an intracellular lifestyle. Conclusions: Our phylogenetic analysis allowed us to track the gene gain and loss events occurring in bacterial genomes during their evolution from a free-living to an intracellular lifestyle.
    [Show full text]
  • Scrub Typhus and Molecular Characterization of Orientia Tsutsugamushi from Central Nepal
    pathogens Article Scrub Typhus and Molecular Characterization of Orientia tsutsugamushi from Central Nepal Rajendra Gautam 1, Keshab Parajuli 1, Mythili Tadepalli 2, Stephen Graves 2, John Stenos 2,* and Jeevan Bahadur Sherchand 1 1 Department of Microbiology, Maharajgunj Medical Campus, Institute of Medicine, Kathmandu 44600, Nepal; [email protected] (R.G.); [email protected] (K.P.); [email protected] (J.B.S.) 2 Australian Rickettsial Reference Laboratory, Geelong, VIC 3220, Australia; [email protected] (M.T.); [email protected] (S.G.) * Correspondence: [email protected]; Tel.: +61-342151357 Abstract: Scrub typhus is a vector-borne, acute febrile illness caused by Orientia tsutsugamushi. Scrub typhus continues to be an important but neglected tropical disease in Nepal. Information on this pathogen in Nepal is limited to serological surveys with little information available on molecular methods to detect O. tsutsugamushi. Limited information exists on the genetic diversity of this pathogen. A total of 282 blood samples were obtained from patients with suspected scrub typhus from central Nepal and 84 (30%) were positive for O. tsutsugamushi by 16S rRNA qPCR. Positive samples were further subjected to 56 kDa and 47 kDa molecular typing and molecularly compared to other O. tsutsugamushi strains. Phylogenetic analysis revealed that Nepalese O. tsutsugamushi strains largely cluster together and cluster away from other O. tsutsugamushi strains from Asia and elsewhere. One exception was the sample of Nepal_1, with its partial 56 kDa sequence clustering Citation: Gautam, R.; Parajuli, K.; more closely with non-Nepalese O. tsutsugamushi 56 kDa sequences, potentially indicating that Tadepalli, M.; Graves, S.; Stenos, J.; homologous recombination may influence the genetic diversity of strains in this region.
    [Show full text]
  • Nov03 POSTER1106.Indd
    The National Cancer Institute Ft. Detrick’s 60th Anniversary story on page 3. News from the NCI-Frederick NOVEMBER 2003 Offi ce of Scientifi c Operations IN THIS ISSUE This year we celebrate the 60th Owned-Contractor Operated (GOCO) Ft. Detrick’s 60th Anniversary 3 anniversary of Fort (Ft.) Detrick. facility. Ft. Detrick’s roots can be traced to The fi rst employees of the NCI- Major Construction Projects 4 a small municipal airport known as Frederick (then known as the Detrick Field1, The Field was named Frederick Cancer Research Center) Building 470 Update 5 to honor Major Frederick L. Detrick, appeared on campus in June 1972 and who served in France during World numbered around 20 by the end of Scientifi c Publications, War I. The fi rst military presence at that month. By 1976 these numbers Graphics & Media News 6 the airfi eld was in 1931 when the had grown to about 750 individuals, Maryland National Guard established and by 1987 the staff numbered over Awards 6 a cadet pilot training center at Detrick 1,400 with a budget of nearly $100 Field and subsequently Platinum Publications 8 changed the name to Camp Detrick. Poster-Script 11 As we pause to think about the history of Ft. Did You Know? 12 Detrick and the many contributions that the Transfer Technology Branch 14 staff of Ft. Detrick has made in the areas of Community Outreach 15 infectious disease and national defense, it Offi ce of Diversity and seems that now is an Employee Programs 16 appropriate time to also look back at the history Environment, Health, and Safety of the NCI here at Ft.
    [Show full text]
  • Scientific Program Table of Contents
    Scientific Program Table of Contents Scheduling and locations are subject to change without notice. Please check the onsite newsletter each morning for changes Sunday, July 15 SYMPOSIA AND ORAL SESSIONS ASN-ADSA-ASAS Preconference: Regulation of Nutritional Intake and Metabolism ................................................................49 Triennial Reproduction Symposium: Impediments to Fertility in Domestic Animals ...............................................................49 Monday, July 16 POSTER PRESENTATIONS Animal Health I ...................................................................................................................................................................................................51 Breeding and Genetics: Fertility and Early-Life Traits ............................................................................................................................52 Companion Animals .........................................................................................................................................................................................53 Dairy Foods ..........................................................................................................................................................................................................54 Forages and Pastures I ......................................................................................................................................................................................55 Graduate
    [Show full text]
  • Persistence of Orientia Tsutsugamushiin Humans
    ORIGINAL ARTICLE Infectious Diseases, Microbiology & Parasitology http://dx.doi.org/10.3346/jkms.2012.27.3.231 • J Korean Med Sci 2012; 27: 231-235 Persistence of Orientia tsutsugamushi in Humans Moon-Hyun Chung1, Jin-Soo Lee1, We investigated the persistence of viable Orientia tsutsugamushi in patients who had Ji-hyeon Baek1, Mijeong Kim1, recovered from scrub typhus. Blood specimens were available from six patients with scrub and Jae-Seung Kang2 typhus who were at 1 to 18 months after the onset of the illness. The EDTA-treated blood specimens were inoculated into ECV304 cells, and cultures were maintained for 7 months. 1Departments of Internal Medicine, and 2Microbiology, Inha University School of Sequencing of the 56-kDa type-specific antigen gene ofO. tsutsugamushi was performed Medicine, Incheon, Korea to ascertain the homology of isolates. O. tsutsugamushi was isolated from all six patients, and nucleotide sequences of isolates serially collected from each patient were identical in Received: 9 October 2011 all five patients in whom nucleotide sequences were compared. One patient relapsed 2 Accepted: 3 January 2012 days after completion of antibiotic therapy; two patients complained of weakness for 1 to Address for Correspondence: 2.5 months after the illness; one patient underwent coronary angioplasty 6 months later; Jae-Seung Kang, MD and one patient suffered from a transient ischemic attack 8 months later. This finding Department of Microbiology, Inha University School of Medicine, 27 Inhang-ro, Jung-gu, Incheon 400-712, Korea suggests that O. tsutsugamushi causes chronic latent infection, which may be associated Tel: +82.32-890-0952, Fax: +82.32-881-8559 with certain clinical illnesses, preceded by scrub typhus.
    [Show full text]
  • Bioterrorism, Biological Weapons and Anthrax
    Bioterrorism, Biological Weapons and Anthrax Part IV Written by Arthur H. Garrison Criminal Justice Planning Coordinator Delaware Criminal Justice Council Bioterrorism and biological weapons The use of bio-terrorism and bio-warfare dates back to 6th century when the Assyrians poisoned the well water of their enemies. The goal of using biological weapons is to cause massive sickness or death in the intended target. Bioterrorism and biological weapons The U.S. took the threat of biological weapons attack seriously after Gulf War. Anthrax vaccinations of U.S. troops Investigating Iraq and its biological weapons capacity The Soviet Union manufactured various types of biological weapons during the 1980’s • To be used after a nuclear exchange • Manufacturing new biological weapons – Gene engineering – creating new types of viruses/bacteria • Contagious viruses – Ebola, Marburg (Filoviruses) - Hemorrhagic fever diseases (vascular system dissolves) – Smallpox The spread of biological weapons after the fall of the Soviet Union •Material • Knowledge and expertise •Equipment Bioterrorism and biological weapons There are two basic categories of biological warfare agents. Microorganisms • living organic germs, such as anthrax (bacillus anthrax). –Bacteria –Viruses Toxins • By-products of living organisms (natural poisons) such as botulism (botulinum toxin) which is a by- product of growing the microorganism clostridium botulinum Bioterrorism and biological weapons The U.S. was a leader in the early research on biological weapons Research on making
    [Show full text]
  • Identification of Trombiculid Chigger Mites Collected on Rodents from Southern Vietnam and Molecular Detection of Rickettsiaceae Pathogen
    ISSN (Print) 0023-4001 ISSN (Online) 1738-0006 Korean J Parasitol Vol. 58, No. 4: 445-450, August 2020 ▣ ORIGINAL ARTICLE https://doi.org/10.3347/kjp.2020.58.4.445 Identification of Trombiculid Chigger Mites Collected on Rodents from Southern Vietnam and Molecular Detection of Rickettsiaceae Pathogen 1, 2, 1 3 4,5, 4,5, Minh Doan Binh †, Sinh Cao Truong †, Dong Le Thanh , Loi Cao Ba , Nam Le Van * , Binh Do Nhu * 1Ho Chi Minh Institute of Malariology-Parasitology and Entomology, Ho Chi Minh Vietnam; 2Vinh Medical University, Nghe An, Vietnam; 3National Institute of Malariology-Parasitology and Entomology, Ha Noi, Vietnam; 4Military Hospital 103, Ha Noi, Vietnam; 5Vietnam Military Medical University, Ha Noi, Vietnam Abstract: Trombiculid “chigger” mites (Acari) are ectoparasites that feed blood on rodents and another animals. A cross- sectional survey was conducted in 7 ecosystems of southern Vietnam from 2015 to 2016. Chigger mites were identified with morphological characteristics and assayed by polymerase chain reaction for detection of rickettsiaceae. Overall chigger infestation among rodents was 23.38%. The chigger index among infested rodents was 19.37 and a mean abun- dance of 4.61. A total of 2,770 chigger mites were identified belonging to 6 species, 3 genera, and 1 family, and pooled into 141 pools (10-20 chiggers per pool). Two pools (1.4%) of the chiggers were positive for Orientia tsutsugamushi. Rick- etsia spp. was not detected in any pools of chiggers. Further studies are needed including a larger number and diverse hosts, and environmental factors to assess scrub typhus. Key words: Oriental tsutsugamushi, Rickettsia sp., chigger mite, ectoparasite INTRODUCTION Orientia tsutsugamushi is a gram-negative bacteria and caus- ative agent of scrub typhus, is a vector-borne zoonotic disease Trombiculid mites (Acari: Trombiculidae) are ectoparasites with the potential of causing life-threatening febrile infection that are found in grasses and herbaceous vegetation.
    [Show full text]