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Literatur 663 Cavus Und Kyphoskoliose Sowie Generalisierten Krampfanfallen Gekennzeichnet Literatur 663 cavus und Kyphoskoliose sowie generalisierten Krampfanfallen gekennzeichnet. Die klini­ sche Manifestation der Erkrankung korrelierte mit einem Befall nahezu aller neuronaler Systeme. Intranukleiire eosinophile hyaline Einschliisse lieBen sich in nahezu allen zentralen, peripheren und autonomen Neuronen nachweisen. Die Pathogenese der neuronalen Ein­ schliisse ist unklar, doch vermuten die Autoren, daB es sich urn eine metabolische Starung handelt, die das nukleiire Protein der Neurone betrifft und nicht auf eine Virusinfektion zuriickzufiihren ist. Die hyalinen Einschliisse bestehen allerdings bei dem Fall von SUNG et al. (1980) elektronenmikroskopisch aus geraden Filamenten, die in verschiedenen Richtungen angeordnet sind, bei unserem Fall aber aus granuUiren, nicht fila­ mentosen Substanzen. 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Churchill, London pp 143-202 Adams RD (1975) Diseases of muscle. A study in pathology, 3rd edn. Harper & Row, New York 588 p Adams RD, Denny-Brown D, Pearson CM (1962) Diseases of muscle. A study in pathology, 2nd edn. Harper & Row, New York, 735 p. Reprinted 1965 Adams RD, Rebeiz J (1966) Histopathologie der myotonischen Erkrankungen. In: Kuhn E (Hrsg) Progressive Muskeldystrophie, Myotonie, Myasthenie. Springer Berlin Heidel­ berg New York, S 191-203 Adornato BT, Kagen LJ, Garver FA, Engel WK (1978) Depletion of serum hemopexin in fulminant rhabdomyolysis. Arch Neurol 35, 547-548 Adrian ED, Umrath K (1929) The impulse discharge from the Pacinian corpuscle. J Physiol (Lond) 68, 139-154 Afifi AK, Aleu FP, Goodgold J, MacKay B (1966) Ultrastructure of atrophic muscle in amyotrophic lateral sclerosis. Neurology (Minneap) 16, 475--481 664 Literatur Afifi AK, Bergman RA, Zellweger H (1973) A possible role for electron microscopy in detection of carriers of Duchenne type muscular dystrophy. J Neurol Neurosurg Psychiat 36,643-650 Afifi AK, Der Kaloustian VM, Bahuth NB, Mire-Salman J (1974) Concentrically laminated membranous inclusions in myofibres of Dygve-Melchior-Clausen syndrome. J neurol Sci 21, 335-340 Afifi AK, Frayha RA, Bahuth NB, Tekian A (1980) The myopathology of Behcet's disease A histochemical light, and electron-microscopic study. J neurol Sci 48, 333-342 Afifi AK, Ibrahim MZM, Bergman RA, Abu Haydar N, Mire J, Bahuth N, Kaylani F (1972) Morphologic features of hypermetabolic mitochondrial disease. A light micro­ scopic, histochemical and electron microscopic study. J neurol Sci 15, 271-290 Afifi AK, Rebeiz J, Mire J, Andonian SJ, Der Kaloustian VM (1972) The myopathology of the prune belly syndrome. 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