Human General Histology
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116 شپږم څپرکي پوست )جلد( Skin & its Appendages stratified squamous Epidermis dermis epithelium subcutis dermis (wave) (straight) dermal papillae epidermal papillae epidermis epidermis 117 شپږم څپرکي پوست )جلد( (print) Epidermis stratified squamous epidermis Stratum basale (Basal lamina) stratum basale basal layer stem cells keratinocytes mitosis stratum germinal layer germinativum basal Stratum spinosum desmosome (keratinocytes) desmosome stratum spinosum (spines) stratum spinosum prickle cells keratinocytes keratin felaments (fibrils) desmosome fibrils stratum spinosum germinative zone epidermis stratum basalae stratum spinosum stratum granulosum 118 شپږم څپرکي پوست )جلد( keratohyalin keratin (pyknotic) filametns keratohyalin lucid=clear stratum granulosum stratum lucidum stratum corneum keratin filaments carbohydrates epidermis zone stratum granulosum stratum lucidum Stratum corneum stratum lucidum stratum granulosum of keratinization dermis 119 شپږم څپرکي پوست )جلد( Dermis epidermis papillary (reticular layer) papillary papillae dermal papilla tactile papillae (capillaries) corpuscles dermis (elastic fibers) dermis (adipose tissues) (superficial fascia) 1,9,3 (stratified stratum squamous epi) corneum Keratinocyte stem keratinocytes stem cells stratum spinosum keratinocytes intermediate cells keratinocytes (keratin) (intermediate filaments) epidermis a tonofibrils cytokeratin filaments stratum spinosum 120 شپږم څپرکي پوست )جلد( keratin filaments tonofibrils stratum granulosum epidermal b keratohyalin granules cysteine histidine (keratin filaments) c stratum granulosum keratohyaline granular d lamellated glycophospholipids keratosome bodies epidermis stratum corneum epidermis stem keratinocytes stem stem epidermis epidermal proliferation unite dendritic 121 شپږم څپرکي پوست )جلد( (pigmentation of the skin) stratum spinosum melanin melanoblasts melanocytes melanocytes neural crest epidermis dermis germinative zone germinative zone melanocytes melanocytes dendritic (melanocytes) melanocytes dendritic macrophages cells tyrosine (eumelanin) dihydroxy-phenylalanine (DOPA) tyrosine DOPA DOPA melanocytes melanin DOPA melanocytes melanin DOPA melanocytes DOPA melanosome melanocytes melanosome keratinocytes germinative zone (pigments) haemoglonin epidermis oxyheamoglobin 122 شپږم څپرکي پوست )جلد( (pale) Epidermis Dendritic cells of langherhance Stratum spinosum dendritic melanocytes keratinocytes melanocytes Dendritic Dendritic cells of langherhance bone marrow mononuclear phagocyte system T-lymphocytes birbeck bodies langherhance bodies Epidermis (chronic skin disorder) allergy Cells of Merkel Epidermis Dermis dermis cleavage line 123 شپږم څپرکي پوست )جلد( dermis elastic dermis Scar tissue lineagravidarum (arterial plexus) deep fascia rete (plexus) dermis reticular plexus plexus dermal papillae rete subpapillare plexus papillary plexux capillaries loops dermal papilla epidermis epidermis dermal diffusion dermal plexus papillae deep fascia arterio-venous anastomoses 124 شپږم څپرکي پوست )جلد( dermis autonomic epidermis erector pilli myoepilthial scrotum (nipple) dermis 9,12,3 : microorganisms poisons (melanin) Ultra violate vitamin D arterio-venous anastomoses (capillaries) 125 شپږم څپرکي پوست )جلد( 5,12,3 (appendages the skin) mammary sebaceous glands (Hair) eyelids shaft Root (root) Bulb 126 شپږم څپرکي پوست )جلد( hair papilla dermis bulb hair follicle tubular Bulb follicles shaft stratum corneum (cortex) (Medulla) medulla medulla cuticle 127 شپږم څپرکي پوست )جلد( medulla cornified (bubbles) Follicle epidermis follicles follicle stratum corneum dermis follicles (Inner root sheath): –I stratum spinosum (outer root sheath) II dermis III follicles cuticle cuticle cornified stratum Huxley’s epithelialegranuloferum trichohyaline granules eosinophilic inner root sheath stratum epithelialepallidum henle’s (outer root sheath) stratum spinosum epidermis bulb 128 شپږم څپرکي پوست )جلد( germinative matrix stratum spinosum bulb mitotic keratinization papilla inner root sheath follicle germinatve matrix outer root sheath (connective outer root sheath (Basal layer) (basal lamina) tissue sheath) glassy membrane PAS-positive eosinophilic dermis connective tissue sheath sebaceous glands sebaceous follicle (insertion) epidermis dermis follicles Fundus sebaceous gland Infundibulum Arector pili infundibulum Isthmus 1,3,9 inferior segment Inferior segment Arector pili muscles dermal papilla dermis connective tissue sheath follicle hair follicle sebaceous 129 شپږم څپرکي پوست )جلد( sebaceous sympathetic Arrectorpili muscle Sebaceous glands (hair follicles) alveoli alveoli alveoli follicle alveoli BM alveoli alveoli sebaceous Sebum sebaceous holocrine sebum sebum cholesterol esters triglyceride cholesterol sebaceous Meibonian tarsal glands eyelids montgomery’s sebaceous sebaceous (breast) tubercles sebaceous glands 3,1,12 130 شپږم څپرکي پوست )جلد( (Nails) proximal distal (body) nail bed Radix(root) (nail groove) keratinizing stratum lucidum stratum corneum keratin germinatve zone stratum basale stratum spinosum germinal matrix germinative zone proximal nail folds germinal matrix germinal matrix proximal nail folds lunule germinal matrix (thumb ) (fibrous tissues) (distal phalanx) germinal matrix germinative zone (nail bed) sterile matrix sterile dermis matrix dermal papillae matrix dermal papillae 131 شپږم څپرکي پوست )جلد( (roots) proximal nail folds lateral nails folds lateral nail folds stratum proximal nail folds lateral nail groove stratum corneum corneum eponychium stratum corneum nail bed hyponychium (distal phalanx) dermis dermis (arterio-venous anastomoses) germinal matrix nail bed nail root germinal matrix 132 شپږم څپرکي پوست )جلد( (Sweat glands) Typical sweat glands holocrine apocrine merocine(ecrine) merocrine (tube) fundus (body) dermis duct epidermis dermis epidermis tube pseudostratifiedEpi- BM RNA BM 133 شپږم څپرکي پوست )جلد( PAS-positive mucopoysacchrides mucoid microvilli myoepithelial basal lamina duct epidermal epidermis cholinergic myoepithelial Atypical sweat glands merocrine typical apocrine apocrine Apocrine (glans penis) (penis) (areola) Merocrine apocrine apocrine a b (hair follicles) c d 134 شپږم څپرکي پوست )جلد( merocrine holocrine apocrine e f adrenergic cholinergic typical cercuminous glands ciliary eyelids (wax) 1,5,9, glands.