the ecord U. S. DEPARTMENT OF April 5, 1977 NATIONAL INSTITUTES OF HEALTH HEALTH, EDUCATION, AND WELFARE Vol. XXIX, No. 7 Maureen Miles Named Gov't Officials Are Invited Participants Dr. Thomas Malone contract coordinator, /n flecolI)fc/nonf ON A Research Discussion Civil Rights Concerns On March 28 local, state, and Federal Government representatives met Appointed to Post Maureen B. E. Miles has recently at NIH to hear a discussion of recombinant DNA research issues. been appointed contract compliance Dr. Donald S. Fredrickson, NIH Director, introduced the topics and coordinator in the Division of Con- speakers: As Deputy Director tracts and Grants, Office of the DNA Technology and a Re- NCI; Director. view of Actions Since 1974, Dr. • The NIH Advisory Committee I' Her responsibilities are to de- William Gartland, director, Office and the Guidelines, Dr. DeWitt velop and sustain a viable and of Recombinant DNA Activities; Stetten, NIH Deputy Director for dynamic Civil Rights Program in • Principles of Physical Con- Science; technical assistance, staff education tainment, Dr. Emmett Barkley, • NIH Research Facility Plans, efforts, and data collection related director, Office of Research Safety, Dr. John Nutter, special assistant to compliance activities so that National Cancer Institute; to the deputy director, National affirmative measures are taken to • Principles of Biological Con- Institute of Allergy and Infectious ensure nondiscrimination against tainment, Dr. Susan Gottesman, Diseases. women and other minorities em- Two NIAID researchers de- ployed by NIH contractors and scribed Risk Assessment in repre- grantees. HEW Secretary Califano sentative experiments. Dr. Malcolm Due to the diverse nature of Appoints a Committee Martin discussed present studies; NIH programs and compliance di- To Find New NCP Head Dr. Wallace Rowe, future studies. rectives, there will be some inter- Dr. Philip Leder of the National action with other Federal agencies HEW Secretary Joseph A. Cali- Institute of Child Health and Hu- on contract compliance problems of fano, Jr., has appointed a search man Development and Dr. Maxine mutual concern. committee to find the best qualified Singer, NCI, presented a discussion individual to head the National of free-ranging research. Held EEO Jobs Cancer Program. As Deputy Director, Dr. Malone will Prior to coming to NIH, Ms. Attending were: representatives assist in the administration and man- Dr. Ivan L. Bennett, Jr., Provost of Senator , Sena- Miles was an Equal Opportunity and Dean of the New York Uni- agement of NIH. Specialist for several years with tor , Representative versity Medical Center, will serve Newton Steers, Representative Dr. Thomas E. Malone has been the Office of Federal Contract Com- as chairman. pliance Programs in the Depart- Goodloe Byron, Montgomery appointed Deputy Director of NIH. ment of Labor. Dr. Frank Rauscher, the former County Executive James Gleason, Selection of Dr. Malone, cur- In this position she monitored Director, resigned Oct. 31, 1976. and the Mayor of Fredrick City. rently NIH Associate Director for the Contract Compliance Division's The ad hoc search committee Also present were: the Com- Extramural Research and Train- Program of the Office for Civil represents both public and private manding Officer of Ft. Detrick, the ing, was announced March 24 by Rights in HEW. medical research: acting chairman of the Frederick NIH Director Dr. Donald S. Fred- She has also worked as an Equal Dr. Bruce Ames, department of County Board of Commissioners, rickson. The post had been vacant biochemistry, University of Cali- the Frederick County Health Offi- since September 1976. fornia, Berkeley; Drs. Harold cer, the Montgomery County Health Amos and Mary Ellen Avery, Har- Officer, and members of the Mary- Secretary Califano Comments vard Medical School; Dr. Donald S. land State Health Department and "The designation of Dr. Malone Fredrickson, NIH Director; Dr. the Frederick County Medical as Deputy Director will bring the Leon Jacobs, NIH Associate Direc- Association. top management of NIH to full tor for Collaborative Research strength by promoting one of its (alternate). Town Meeting Tomorrow: leading administrators," said Also, Dr. Robert C. Gallo, Na- NIA Director Is Panelist Joseph A. Califano, Jr., Secretary tional Cancer Institute; Dr. Charles of Health, Education, and Welfare. G. Moertel, Mayo Clinic and Mayo Our Elderly Today and To- "I believe this is a splendid Foundation; and Benno C. Schmidt, morrow is the theme of the choice," Secretary Califano said. J. H. Whitney & Company, N.Y. National Town Meeting to be "Dr. Malone will bring great held tomorrow, April 6 from strength to the number two posi- Dr. Seymour Perry, special as- 10:30 to 11:30 a.m. in the sistant to the NIH Director, will tion because of his extensive ex- Kennedy Center Concert Hall. perience in the extramural pro- serve as executive secretary for the Senator Frank Church and committee. grams which makeup almost 90 Dr. Robert N. Butler, Direc- percent of NIH's activities." tor of the National Institute Before becoming Associate Di- Ms. Miles plans to assure that women's Employment Opportunity Special- on Aging, will comprise the and minority firms may compete for ist with NASA's Goddard Space rector for Extramural Research panel, moderated by Nancy and Training in August 1972, Dr. contracts and grants. She will serve as Flight Center, and the Treasury Hicks. an extension of the Office for Civil Department. Malone was associate director for The program will be carried Extramural Programs at the Na- Rights, HEW, receive compliance in- Ms. Miles is a graduate of Mor- live on radio station WAMU- formation regarding NIH contractors gan State University, and has done tional Institute of Dental Research FM (88.5) and will be re- from October 1969. and grantees, attempt to resolve the graduate work at Howard Univer- broadcast on WETA-FM (90.9) problems and report any specific con- sity, D.C. Teachers' College, and on Sunday, April 9 at 9 p.m. He joined NIH in 1962 as a cerns to OCR for further action. the University of . (See DR. MALONE, Page 5) Page 2 April 5, 1977 THE NIH RECORD Record Published biweekly at Bethesda, Md., by the Editorial Operations Branch, Division of Public Information, for the information of employees of the National Institutes of Health, Department of Health, Education, and Welfare, and circulated by request to interested writers and to investi- gators in the field of biomedical and related research. The content is reprintable without permission. Pictures are available on request. The NIH Record reserves the right to make corrections, changes, or dele- tions in submitted copy in conformity with the policies of the paper and the Department of Health, Education, and Welfare.

NIH Record Office Bldg. 31, Rm. 2B-03. Phone 49-62125

Editor Frances W. Davis Associate Editor Fay Leviero Associate Editor Heather Banks A NEW LOOK has been added to the Bldg. 31 Blind Stand, now doubled in size and returned to its "old place" next to the cafeteria. Robert Mackinson (I), Staff Correspondents business counselor with Blind Industries and Services of Maryland, discusses the ADA, Judy Fouche; CC, Susan Gerhold; DCRT, Frances Sarles; DRG, toys, games, and greater selection of greeting cards and snacks now available. Sue Meadows; DRR, Jerry Gordon; DRS, Arthur F. Moore; FIC; George Catherine Reilly (r)—operator of the stand since May 1976—says many Presson; NCI, Dr. Robert M. Hadsell; NEI, Julian Morris; NHLBI, Bill people never found its temporary 3-month location around the corner. Well- Sanders; NIA, Ann Shalowitz; NIAID, Jeanne Winnick; NIAMDD, known by many NIH'ers, she operated the stand in Bldg. 35 for 6 years and one Pat Sheridan; NICHD, Tina Mclntosh; NIDR, Sue Hannon; NIEHS, at the AEC for 6 years previously. Elizabeth Y. James; NIGMS, Wanda Warddell; NIMH, Betty Zubovic; NINCDS, Jeannette Belliveau; NLM, Roger L. Gilkeson. Blue Cross/Blue Shield, TRAINING TIPS Third Symposium Hosted Mark Season Opening Aetna Will Provide Aid In Filing Claims, April! 8 The Training and Education By CC Nursing Dept. Of Men's Golf League: Branch will offer the following On Issues and Answers Representatives of Blue Cross/ Communications courses. HEW April 20 at First Tee Blue Shield and Aetna Life and Form 350 is required. The Clinical Center Nursing De- Casualty Company will be at NIH Courses, dates, and application partment's third annual research The R&W Golf Association will to assist employees in filing claims deadlines are: symposium was held March 16 in begin the 1977 season April 20 at for benefits provided under the Basic Time and Attendance, the Masur Auditorium. Bretton Woods in Seneca—one of Federal Employees Health Benefits April 21; April 11 Vernice Ferguson, chief of the the finest conditioned golf courses Program. Scientific Terminology, May 3- department, hosted the 180 guests in metropolitan Washington, ac- Upon request, assistance will June 21; April 25 and employees attending the sym- cording to new NIHGA president also be available for claims sub- Basic Mag Card I (MCST), symposium was held March 16. Larry Willhite. mission under any of the other May 5 and May 6; April 26 Lindeman Is Keynoter Following recent planning meet- plans under FEHBP. ings, two playing formats popular Advanced Mag Card I (MCST), Dr. Carol Lindeman, Dean, School The representatives will be in May 5 and May 6; April 26 in previous years will be combined Bldg. 31, Rm. 11A10 on Monday, of Nursing, University of Oregon, into a new format featuring team Basic Memory Typewriter, May Portland, gave the keynote address. April 18 from 9 a.m. to 12:15 p.m. 4; April 26 play with eight teams: Employees seeking assistance are Advanced Memory Typewriter, Susan Molloy Hubbard of the • Four 18-hole stroke play out- Cancer Nursing Service moderated asked to call the Employee Rela- May 4; April 26 ings open to all members, with the tions and Recognition Branch, the five panelists: Dr. Rita Chow, lowest five net scores on each team Small Purchase Procedures, May deputy chief officer and deputy di- DPM, on Ext. 64973 for an appoint- 17-19; May 5 counting toward an aggregate ment. rector, Office of Long Term Care, team score. The eight teams will The following Civil Service Com- P.H.S.; Dr. Laurel Archer Copp, compete for the championship. mission Course requires HEW Dean and professor, School of Form 350 and OF 37. Nursing, University of North Car- 7 Match Play Rounds Decision Making for Secretaries, olina at Chapel Hill. • Seven 18-hole match play June 6-9; application deadline: Also, Dr. Susan Gortner, chief, rounds involving only six players May 7. nursing research branch, Division per round from each team. In Further information is available of Nursing, Bureau of Health Man- match play competition, each team from B/I/D personnel offices or by power; Col. Rosemary McCarthy, will play each of the other seven calling Training and Education D.N.Sc, nursing consultant to the teams once. The same eight teams Branch, Ext. 62146. Surgeon General of the Army; and will compete for the match play Dr. Margaret McCarkle, assistant championship. FAES Series Adds Memorial professor, department of compara- Dues will continue at $5. The Cello Concert on Sun., April 17 tive nursing care systems, School eight teams will be formed insofar of Nursing, University of Wash- as possible from 1976 team rosters. Stephen Kates—accompanied by ington, Seattle. pianist Samuel Sanders—will play The rules committee, chaired by cello sonatas by Francoeur, Bee- Ralph Stork, will consider revi- thoven, Debussy, and Rachmaninoff Run! Be an R&W Officer sions to the NIHGA rules and re- in an additional concert in this Join those running for one of port to the Board. year's series sponsored by the the offices vacant in the Recre- A banquet and awards ceremony THE HIGH WINDS of March 24 Foundation for Advanced Educa- ation and Welfare Association: will be held after the 1977 season, cracked a window in the Editorial Op- tion in the Sciences. president, second vice-presi- but no later than Nov. 30. erations Branch, OD, in Bldg. 31. dent, and assistant treasurer. News items and suggestions are Fortunately, no one was injured. Re- Piatigorsky Remembered Send your name—as soon as welcome and can be phoned in to ponding quickly to tape up the casu- The concert, in memory of cellist possible; by April 26 at the Bill Quinlan, Ext. 62308. New alty were (I to r) Roger Thompson, Gregor Piatigorsky, will be held latest^to the R&W Office, NIHGA members—always welcome Robert Bell, and Orville Smith of the Sunday, April 17 at 4 p.m. in the Bldg. 31, Rm. 1A17. —should contact any NIHGA mem- North Building Unit, Plant Engineering Masur Auditorium. Admission is ber or Larry Willhite, Ext. 63381. Branch, DAS. by ticket only. THE NIH RECORD April 5, 1977 Page 3 New Construction at CC Two Groups Study Employee Conflicts, Bruno Vasta Is Named Will Cause Alterations Dissatisfaction, Look to NewApproaches Branch Chief at NLM Two groups of NIH employees are currently working together to design In Parking and Traffic a study which will identify causes of employee dissatisfaction and con- Site preparation for the new flict at NIH, and approaches for dealing more effectively with such Ambulatory Care Research Facility problems. —to be located in front of the These groups—designated as the Panel Listed Clinical Center—is scheduled to be- Task Force for the Study of Em- The Panel members and the con- gin about April 16. Actual con- ployee Conflict, and the Review stituencies they represent are: struction will start about 1 month Panel for the Study of Employee J. Harrison Ager, Ext. 63670, later. Conflict—were established under EEO Coordinators; Site preparation will cause three charters approved by the NIH Ann Marie Doran, Ext. 63253, major traffic changes on the cam- Deputy Director in August 1976. Non-supervisory Registered pus beginning April 16: Nurses; 1) The front entrance of the CC Concerns Detailed Sol del Ande Eaton, Ext. 65141, will close and remain closed Their areas of concern range NIH Women's Advisory Council; throughout the construction period. from circumstances which gener- Anthony Gaetano, Ext. 66391, The new major entrance will be ate complaints of unfair treatment National Association of Super- at the rear (south side) of the visors membership at NIH; building, between the NIH library and discrimination to environ- mental factors and supervisory William 0. Mitchell, Ext. 62787, In his new position, Mr. Vasta will be and Masur Auditorium. The new Research Support Staff; responsible for the Library's indexing outpatient entrance is near the practices which produce good working relationships. Dr. Marie U. Nylen, Ext. 61483, operations, on-line training and serv- Blood Bank. Senior B/I/D Staff; ice activities, and the preparation of 2) The parking lots located The Task Force is a small work Adeline J. Obot, Ext. 64494, Index Medicus and specialized bibli- north of Bldg. 10—between Con- group consisting of: SHER; ographies. vent Drive and Memorial Drive— James S. Alexander, Clinical Virginia T. Ono, Ext. 65231, will close. All reserved parking Center EEO Coordinator; Secretaries; Bruno M. Vasta, formerly chief (red permits, volunteers, and out- Raymond J. Jackson, Director, Bruce K. Schrier, Ext. 63298, of the Toxicology Information patient lots) will be replaced by Division of Equal Opportunity; Research Investigators; Services Branch, Specialized Infor- marked areas to the rear of the Linnie C. Sloan, Ext. 67467, EEO mation Services at the National building. Rosalind B. Marimont, research Library of Medicine, has been ap- mathematician, NINCDS; Counselors; Other Spaces Available Kent A. Smith, Ext. 66491, Ex- pointed chief of the NLM Biblio- Edward E. Nicholas, Jr., Direc- graphic Services Division, Library Other spaces lost due to the con- tor, Division of Personnel Manage- ecutive Officers; struction will be replaced by the Charles E. Walker, FTS 8-629- Operations. same number of spaces in other ment; and three staff members. 3315, Personnel Specialists; He succeeds William Caldwell, lots throughout the reservation. The Review Panel serves as an Brenda Watts, Ext. 61988, Wage now devoting full time to technical 3) METRO buses will be re- advisory group to the Task Force Grade Employees; and processing of the literature. routed to South Drive, just behind and consists of 14 members ap- Mary L. White, Ext. 65385, Metal Mr. Vasta has been at NLM for the CC. Pull-offs and passenger pointed by the NIH Director to Trades Council membership at 7 years, heading the SIS branch shelters have been constructed, represent segments of the NIH NIH. responsible for TOXLINE and along with walks and additional community which have a special CHEMLINE services. Before join- lights. interest in the content of the study. Mark J. Lombard! Dies; ing the Library, he was associated Further details will be available with the then National Heart In- within the next few weeks. Met Feb. 8 Was Technician in NIDR stitute, the Department of Agri- The Review Panel and the Task Mark J. Lombardi, biological culture, and the Food and Drug Force met together on Feb. 8 to dis- laboratory technician of the Labo- Administration. cuss a first draft of the study out- ratory of Oral Medicine, National For the last 12 years, he has line. They will meet again in late Institute of Dental Research, died been involved in the information April or early May to reach final of a heart attack at his home in science field. agreement on study objectives and Brunswick, Md., on Feb. 10. Active in many professional so- to discuss study methodology and Mr. Lombardi joined the NIDR cieties, he has just completed a criteria for selection of a manage- staff in 1964 after completing 22 term as chairman of the American ment consultant contractor. years of military service. In 1972, Chemical Society's Division of while working with the Institute's Chemical Information. In preparation for that meeting, Laboratory of Microbiology and Review Panel members are inter- Immunology, he received special Executive of the Week — ested in hearing from other NIH recognition for his major contribu- employees who could contribute to tions to the program of the Virol- WGMS Honor Bestowed the study design or have informa- ogy Section. On Dr. E. Hasselmeyer tion that should be picked up dur- ing the data gathering phase. Dr. Eileen G. Hasselmeyer was DNA Policy: Topic of STEP recently selected as Executive of Lecture by Dr. Perpich the Week on radio station WGMS' MC Youth Advocacy Program Dr. Joseph G. Perpich, NIH Executive Salute. Seeks Volunteers This Month Associate Director for Pro- Chief of the Pregnancy and In- The Youth Advocacy Program is gram Planning and Evalua- fancy Branch, Center for Research accepting applications from volun- tion, will discuss Recombinant for Mothers and Children in the teers at least 18 years of age for DNA Research—Public Policy National Institute of Child Health Rayna J. Blake, financial management training to begin April 25. Needed Aspects at a lecture Thursday, and Human Development, she was specialist, has been appointed Wom- are volunteers with spare time on April 14 from 9:15 to 10:15 nominated for the tribute by co- en's Program Coordinator for NICHD. weekends and able to establish sup- a.m. in Wilson Hall, Bldg. 1. workers Sheri Birnbaum, Linda The only coordinator at the Institute The lecture—open to all—is Childs, Linda Payne, Karen Chew- level, she is a link between the NICHD portive relationships with youth on part of a series in the Con- ning and Joan Swaney, who praised EEO Coordinator and the NICHD a one-to-one basis—especially males tinuing Education Program her as ". . . much more than a boss. • Women's Organization, serves as an as role models for adolescent boys. sponsored by the Staff Train- Dr. Hasselmeyer is our friend. . . ." EEO counselor, and maintains contact The application deadline is April ing Extramural Program. As a tribute from the sponsors with the Federal Women's Program 18. For applications and more in- of the program, Dr. Hasselmeyer Coordinator and NICHD delegates to formation, call the Mental Health There is no cure for birth and was given an office plant plus a the NIH Women's Advisory Com- Association of Montgomery County, death save to enjoy the interval.— complimentary dinner at a local mittee. 949-1255. George Santayana. restaurant. Page 4 April 5, 1977 THE NIH RECORD NIGMS Extends MARC Program, Training30-Year NIH Employee Gustav Stern Symposium Charles King Dies; Was Speakers and Awardees MinoritiesEntering Biomedical Careers Chem. Stores Unit Head A new program of awards to help minority schools train undergraduate Include Several NIH'ers honor students for careers in biomedical research and teaching has been The 10th Gustav Stern Sympo- announced by the National Institute of General Medical Sciences. sium on Perspectives in Virology, Dr. Ruth Kirschstein, NIGMS Director, says the awards are intended held recently in New York, this to increase the number of minority students who can compete successfully year honored Drs. Werner and Ger- for entry into graduate programs trude Henle, NCI grantees at Chil- leading to the Ph.D. degree in bio- chosen from honor students in dren's Hospital, Philadelphia, who medical sciences. either their third or fourth year of identified the Bpstein-Barr virus Grants Are Competitive college. Funds may be requested as the cause of infectious mononu- Grants will be made to qualify- for stipends, tuition, and fees. cleosis, and have contributed to the ing institutions on a competitive The Honors Undergraduate basis to develop a strong science Award Program is an extension of understanding of hepatitis and per- biomedical science training support sistent viral infections. curriculum, enhance laboratory and administered by the sponsoring In- The 1977 Gustav Stern Award— faculty capabilities, and assist stu- stitute's Minority Access to Re- for outstanding achievement by a dents with tuition and stipend sup- search Careers (MARC) program. port. scientist aged 35 or less—was pre- Mr. King Eligible institutions include those sented to Dr. Wade Parks of the Other Support Offered On March 22 Charles T. King, 4-year colleges and universities and Other forms of support offered National Cancer Institute. health professional schools within an NIH employee for 30 years, Dr. Parks spoke to symposium by the MARC program are Faculty succumbed to a heart attack while the U.S. and its territories whose Fellowship Awards, which further participants on The Use of RNA student enrollments are drawn sub- performing his duties as head of the training of minority institution the Chemical Stores Unit in the Tumor Viruses to Investigate Cell- stantially from ethnic minority bioscience faculties, and Visiting ular Regulatory Processes, focus- groups—American Indians, Blacks, Division of Administrative Serv- Scientist Awards, which help mi- ices—a position he held since 1954. ing on his research on the RNA Hawaiians, Mexican Americans, nority schools bring outstanding breast cancer and sarcoma viruses and Puerto Ricans. Each grant will Mr. King came to NIH in 1946 scholars to their campuses to and joined the Supply Operations of the mouse. have a commitment of continuing strengthen health science research support, up to a maximum of 5 Branch, DAS, in 1951. Nobel Prize recipients Drs. David and teaching. " 'Rocky,' as I've called him for Baltimore, Salvador E. Luria, and years. Minority institutions wishing to 24 years, was a rare breed," said Thomas H. Weller were among the Schools Select Students apply for the undergraduate Otis Ducker, Director of DAS. "His participants, as were Dr. D. Carle- The selection of students for awards should request application dedication and dependability were ton Gajdusek, 1976 Nobelist, and training will be a prerogative of forms, guidelines, and additional unsurpassed." co-author Dr. Clarence J. Gibbs, the grantee school. On average, information by writing to Elward Mr. King also operated his own Jr., both of the National Institute each grant will encompass training Bynum, MARC Program Director, business in Rockville, Md. He was of Neurological and Communica- for five to ten students, as a rule NIGMS, Bethesda, Md. 20014 or by a member of the VFW and the tive Disorders and Stroke. calling (301) 496-7357. American Legion, and an active Dr. Gibbs reported on their ef- diseases, including kuru and Creutz- member of Clinton AME Zion feldt-Jakob disease. Deadline Is May 15 Church, Rockville, serving on the forts in identifying the manner in Among other leaders of sympo- Completed applications should be which a new group of infective Board of Stewards at the time of sium sessions was Dr. Richard received by the NIH Division of his death. agents—the so-called slow viruses Wyatt of the National InstituU of Research Grants no later than —reproduce. Mr. King planned to retire in Allergy and Infectious Diseases, May 15. July after 34 years of Federal Unique chemical and biological who discussed reovirus-like agents service. characteristics make it possible for (rota viruses) associated with NIH Visiting Scientists He is survived by his wife, Cath- these organisms to produce spor- diarrheal illnesses in animals and erine, two daughters, and one adic, epidemic, and familial chronic man. Program Participants grandchild. 3/4—Dr. Nigel A. Brown, United Kingdom, Environmental Toxicol- NCI Report Is Available ogy Branch. Sponsor: Dr. Robert L. Dixon, NIEHS, Research Tri- On Carcinogenesis Test angle Park, N.C. Availability of a report on ani- 3/6—Dr. Cyril P. Legum, Israel, mal tests of 1,1,1-trichloroethane Neonatal and Pediatric Medicine for cancer-causing activity was an- Branch. Sponsor: Dr. Norman nounced by the National Cancer Kretchmer, NICHD, Bg. 31, Rm. Institute in the March 15 Federal 2A03. Register. The compound was given orally 3/9—Dr. Krishnamoorthy Ven- to rats and mice on a daily basis katasubramanian, India, Labora- for more than a year. According tory of Developmental Biology and to a summary included in the an- Anomalies. Sponsor: Dr. Elliott nouncement, "The neoplasms ob- Schiffmann, NIDR, Bg. 30, Rm. served are not believed attributable 410. to 1,1,1-trichloroethane exposure. 3/13—Dr. Giorgio Bronzetti, It- "Even if such a relationship aly, Laboratory of Environmental were inferred, it would be inappro- Mutagenesis. Sponsor: Dr. Errol priate to make an assessment of Zeiger, NIEHS, Research Triangle carcinogenicity of 1,1,1-trichloro- Park, N.C. ethane on the basis of this test, Dr. Harold S. Ginsberg (1) of Columbia University and Dr. Sarah H. Sell of 3/14—Dr. Ashok Agrawal, India, because of the abbreviated life Vanderbilt University—members of the NIAID Infectious Disease Committee— Environmental Toxicology Branch. spans of both the rats and the chat with Dr. King K. Holmes (r) director of the NIAID Venereal Disease Sponsor: Dr. William E. Wilson, mice." Research Center in Seattle. Dr. Ginsberg chairs the Committee, which met at NIEHS, Research Triangle Park, The tests were part of the NCI NIH March 17-18 to evaluate NlAID's Special Emphasis Program on Biology N.C. Carcinogenesis Bioassay Program. of Sexually Transmitted Diseases and to hear reports from grantees and from the 3/18—Dr. Akio Toh-e, Japan, Copies of the report are available directors of the four VD Research Centers supported by this program in Seattle, Laboratory of Biochemical Phar- from the Office of Cancer Commu- and at Harvard University, Baylor College of Medicine, and Cornell University macology. Sponsor: Dr. Reed B. nications, NCI, Bethesda, Md. in New York. Wickner, NIAMDD, Bg. 4, Rm. 103. 20014. THE NIH RECORD April 5, 1977 Page 5 HI AID Assists Cholera Research in Dacca DR. MALONE X-Ray Mammography (Continued from Page 1) With Recycled NIH Intravenous Bottles Grants Associate, Division of Re- Breast Cancer Screening search Grants. In 1963 he became assistant chief, Research Grants Reports Now Available Section, Extramural Programs, Three scientists, appointed in NIDR, and from 1964 to 1966 October 1975 by the Director of the served as deputy chief, Extramural National Cancer Institute to assess Program Branch, NIDR. the benefits and risks of using From 1967 to 1969, Dr. Malone X-ray mammography in routine was chairman of the department of screening of women for breast can- biology, American University of cer, delivered their individual final Beirut, Lebanon. reports and a set of joint recom- He was born in Henderson, N.C., mendations to NCI March 9. and received the B.S. and M.S. de- Information in two of the three gree from North Carolina College, reports is based on evaluation of Durham, and his Ph.D. from Har- data developed by the Health In- vard University. surance Plan (HIP) study con- ducted in the 1960s. The third re- Recognition Received port is based on many studies of He is a member of numerous pro- exposure to ionizing radiation. fessional organizations in the fields Dr. Lester Breslow, dean of the of health and research administra- School of Public Health, UCLA, re- tion. viewed the benefits of adding mam- Dr. Malone received the DHEW mography to history and physical Superior Service Award in 1970 examination in the HIP study. William Brown, Milton Gross, Ben Burritt, and Dr. Herman (I to r) inspect a Dr. Louis B. Thomas, chief of cart of I.V. bottles prior to boxing, crating, and shipping them to Dacca. and the DHEW Distinguished Service Award in 1974. the NCI Laboratory of Pathology, On a recent site visit to the Cholera Research Laboratory in Dacca, reviewed the tissue samples of Bangladesh, Dr. Carl Miller of the National Institute of Allergy and breast cancer cases discovered in Infectious Diseases witnessed delivery of the first of 15,000 life-saving the HIP study. I.V. bottles contributed by NIH. Dr. Arthur C. Upton, dean of These bottles are part of a unique recycling project which began in Basic Sciences, Health Sciences August 1976 and was the brain- Center, State University of New child of Dr. Miller and Dr. Lloyd about to be disposed of as solid York, Stony Brook, evaluated the Herman, Environmental Safety waste by the Clinical Center. relationship between benefit and Branch of the Division of Research They enlisted the aid of nurses, risk in mammographic screening Services. workers in housekeeping, phar- for breast cancer. Need Known macy, sterile supply, and trans- Each scientist was assisted by portation units in the CC, and the several colleagues. As Cholera Program Officer for packing and shipping department, the Cholera Research Laboratory Supply and Operations Branch, in Direct Inquiries to Dr. Fink in Dacca—supported in part by Bldg. 13. Inquiries about these reports NIAID—Dr. Miller knew first-hand should be directed to Dr. Diane J. the desperate need for special I.V. Worked Extra Hours Fink, Director of the Division of fluids in treating cholera patients. These workers not only made the Cancer Control and Rehabilitation, Cholera—a disease that causes empty bottles available, but also Dr. Miller holds one of the I.V. bottles NCI, (301) 427-7996. intense diarrhea and vomiting—is collected the original shipping car- —formerly discarded—which will be The use of mammography for endemic in Bangladesh, as well as tons, in which the bottles could be sterilized and reused many times for the diagnosis of women who have much of Asia. When a person is stored until crated for shipment to treatment of cholera in Bangladesh. symptoms of breast disease has not stricken with this disease, large Dacca. Many of these employees been questioned and was not con- On arrival in Dacca, the bottles sidered in the studies. amounts of special I.V. fluids must worked on weekends, before and will be sterilized and filled with the be administered promptly or death after hours, and on their lunch special "Dacca solution" used for The reports by Drs. Breslow, may result. hours. the treatment of cholera patients. Upton, and Thomas, now under re- Together, Drs. Miller and Her- Three employees of the packing Since cholera is endemic there, the view at NCI, will be supplemented man worked out the logistics for and crating section in DAS were bottles will be cleaned, refilled, and with a fourth report which will re- salvaging, crating, and shipping responsible for getting the bottles sterilized over and over again, as view and evaluate data from the empty, uncontaminated I.V. bottles and boxes ready for shipment. current Breast Cancer Detection required. Demonstration Project. Proper arrangements were made The fourth report, to be devel- with Abbott Laboratories for the oped by a Working Group led by purchase of the new stoppers and Dr. Oliver Beahrs of the Mayo seals to be used in sealing the bot- Clinic, is expected in June. tles of Dacca solution in Bangla- Together, the four reports will desh. form the basis for a meeting to be Costs Saved held in July to develop a consensus . on the use of X-ray mammography The standard one liter I.V. bottle for routine breast cancer screening. f costs the original user approxi- Neither the structure nor the par- mately $1.40 plus the cost of dis- ticipants in this meeting have yet posal. Since a total of 15,000 bottles been determined. i L i were salvaged for reuse, the joint effort in recycling these bottles by Copies of the "Final Reports of NIH and NIAID is estimated to the National Cancer Institute Ad J144 Hoc Working Groups on Mammog- "OTTl.ES have saved the U.S. Government a total of $25,000. raphy Screening for Breast Cancer and a Summary Report of the Joint Findings and Recommenda- He has an incurable disease who tions" are available from the Office believes all he hears.—Arabic of Cancer Communications, NCI, Mr. Brown packs the boxes in marked crates for shipment to Bangladesh. Proverb. Bethesda, Md. 20014. Page 6 April 5, 1977 THE NIH RECORD More Effective Rabies Vaccine Requires Fewer Injections, U.S.-lran Team Finds A new rabies vaccine used successfully to treat 45 people bitten by rabid animals—called a major medical advance—is made from rabies virus grown in human cells, has no side effects, and protects with only six injections, making it the first completely effective weapon for protecting man against this generally fatal viral infection. in the reported study set out to A team of U.S. and Iranian re- test HDCV in an area of the world searchers, partially supported by where rabies is a serious problem. the National Institute of Allergy Physicians at the Pasteur Insti- and Infectious Diseases, reported tute in Iran collaborated with the their research in the Dec. 13, 1976 U.S. group in using the new vac- issue of the Journal of the Ameri- cine, coupled with antirabies serum, can Medical Association. to treat a group of people severely bitten by rabid dogs and wolves No Cure After Symptoms between June 1975 and January Once symptoms appear, there is 1976. no reliable treatment for rabies. Prompt, post-exposure vaccination As soon as the rabies-exposed ¥ can often prevent development of victims could be reached, 44 of the the disease, but not without poten- 45 were given the antirabies serum At a recent surgery seminar held at the Oregon Regional Primate Center, tially serious risks. for immediate protection. Dr. Gary D. Hodgen of NICHD explains the anatomy involved in a surgical Typically, administration of the At that time—4 to 14 days after technique following a presentation on current research in the Rhesus monkey current rabies vaccine—grown in exposure—they were also given on hormonal changes during pregnancy. NICHD's Donald Lee Barber (rear) duck embryo cells—requires any- their first injection of vaccine, fol- demonstrated new techniques for surgical removal of the pituitary gland. Center where from 14 to 21 injections, lowed by five more shots over a staff members shown are (I to r) : Bill Baughman, Dr. John Hill, and John with no guarantee of adequate im- 3-month period. Ochsner. munological protection. None Developed Rabies In addition, some people experi- Six to 12 months after treatment Nutrition and Reproduction Are Examined, ence allergic reactions to the for- was initiated, the investigators re- eign animal protein, ranging from ported that none of the victims de- Conference Proceedings to Be Published painful swelling to paralysis and veloped rabies or experienced any death. adverse reactions to the vaccine. Considerable research has focused on the relationship between popula- Developed in Philadelphia According to previous rabies sta- tion growth and nutrition. However, interest has centered mainly on food tistics, about 35 percent would have availability, nutrition levels, and death rates. The major role nutrition The new vaccine, developed by died had they not been treated. plays as a birth rate determinant is only now being recognized. Dr. Hilary Koprowski and his co- Scientists and administrators — workers at the Wistar Institute of What is even more striking, say Anatomy and Biology in Philadel- the researchers, is the fact that from the U.S. and foreign coun- tor promoting prolactin release treatment in some cases was tries, together with NIH investiga- from the pituitary to stimulate phia, is made from rabies virus tors, assembled here recently to milk production, indicate it may cultured in Wl-38 cells—fetal hu- started as late as 14 days after exposure. clarify issues and to identify re- have potential as a 'pill' to main- man lung cells widely used in the search needs at a conference on tain lactational amenorrhea. production of other vaccines. Pre- In the past, such delays have in- vious studies indicate that the new variably resulted in failure to pro- Nutrition and Reproduction. ,,,... .,. ,. ., , , human diploid cell vaccine (HDCV) tect some of the exposed people T , „ , K. , Additional Studies Needed The 3-day conference—open to causes virtually no side effects and from rabies death. Such an is highly immunogenic. the public—was sponsored by the approach might both Must Use Immediately Center for Population Research, Promote infant health and prolong Convinced of the vaccine's safety blrth The scientists strongly recom- National Institute of Child Health spacing. It was the consensus and effectiveness, the investigators of the rou that mend the use of antirabies serum and Human Development. g P additional studies with the vaccine for immediate, During the conference, it became are needed on the effects on the passive immunity during the criti- clear that nutrition influences the mother and infant of prolonged ' span of reproductive life. For in- lactational amenorrhea. cal post-exposure period. Other areas They suggest that the next step stance, poor nutrition is associated requiring further with delayed onset of menarche and research, according to participants, in improving rabies treatment is lnclude to produce immune-globulin from premature menopause. Another the effects of nutrition im- human cells to replace the anti- participant presented data indicat- provement on reproductive per- serum of animal origin. ing the relationship between nutri- *°rmance in malnourished popula- tional factors and the ability to tl . ons and their implications for This procedure is limited only by produce children. birth rates, and on contraceptive the availability of donors, such as technology and nutrition, and im- the successfully treated persons in Breastfeeding Discussed plications for fertility intervention the present study. For example, starvation may af- programs. feet libido in both sexes, or cause Finally, the conference stressed Researcher Named decreased potency in males, or the need for clarification of termi- Drs. Mahmoud Bahmanyar, Ah- amenorrhea—absence of menses— nology in order to facilitate under- mad Fayaz, Shokrollah Hour- in females. Other presentations ad- standing across disciplines, cul- Salehi, and Manouchehr Moham- dressed the effect of breastfeeding tures, and nations, madi collaborated with Dr. Kop- on infant survival in developing _ . _ . rowski. Both Institutes are World societies. 0Hier ToP les Listed Health Organization Collaborating The proceedings also noted the Other topics included: hormonal Diane Randolph, of Seneca Valley Centers for Reference and Re- influence of breastfeeding on fer- control of ovulation and lactation; High School, is a 17-year-old Stay-in- search in Rabies. tility. Field study data was de- reproductive endocrinology and School worker for the National Cancer scribed to indicate that some malnutrition; steroid contracep- Institute. On March 11 she was stand- A man's soul may be buried and women who breastfeed may be in- tives and nutrition consequences; fertile for a year or more because f°od intake and fatness as they re- ing in the Clinical Center lobby as perish under a dungheap or in a ate Rosalynn Carter was leaving NIH. furrow of the field, just as well as of lactational amenorrhea. l to fertility; economic determi- Diane asked for and received the First under a pile of money.—Nathaniel According to participants, find- nants of breastfeeding; interna- Lady's autograph. Hawthorne. ings on thyrotropin releasing hor- tional field studies; quantitative mone, TRH, the hypothalamic f ac- (See NUTRITION, Page 7) THE NIH RECORD April 5, 1977 Page 7

Angina Clinical Study Compares Medical NUTRITION (Continued from Page 6) Therapy and Coronary By-Pass Surgery and analytical models of nutrition- Preliminary results of the National Cooperative Study to Compare fertility correlates, and policy Medical and Surgical Therapy for Unstable Angina Pectoris were an- implications. nounced March 9 during the annual meeting of the American College of The proceedings will be pub- Cardiology which was held in Las Vegas, Nevada. lished, edited by Dr. W. Henry Angina pectoris is the chest pain Mosley, professor and chairman, caused when the heart muscle fails that they had experienced chest department of Population Dy- to get enough oxygen to meet its pain of a variable nature occurring namics, Johns Hopkins School of energy demands. "Unstable an- from 12 hours to 4 weeks before Hygiene and Public Health, who gina" describes a changing situa- their actual heart attack. chaired the organizing committee: tion which may imply either chest Thus, some doctors use the term Dr. Corf man, NICHD; Dr. Jean- pain of new onset or a changing "impending heart attack" and Pierre Habicht, Health Resources pattern. "threatened heart attack" or "pre- Administration, PHS; Dr. Robert The randomized study shows sur- infarction angina" in place of un- G. Porter, Brown University; Dr. vival patterns of 149 patients un- stable angina. Jeanne Clare Ridley, Georgetown Arthur D. Fried was recently appointed der medical management for un- Presenting data and background University; Dr. John Standbury, NICHD budget officer. Previously, he stable angina pectoris as opposed on the study conducted by the Massachusetts Institute of Tech- was a budget analyst in NHLBI and a to 141 patients who underwent National Heart, Lung, and Blood nology ; and Dr. Joe Wray, Harvard program specialist with the Bureau of coronary artery by-pass surgery. Institute were: NHLBI Director University. Health Manpower Education, then an Recently the prinicpal investiga- Dr. Robert I. Levy; Dr. Peter L. NIH component. Mr. Fried came to tors in this study convened in Frommer,, NHLBI associate direc- along with the nitrates but some- NIH in 1970 as a management in- Bethesda to discuss this data. In tor for Cardiology; Dr. Michael B. times alone is propranolol. Pro- tern, after graduate work in finance at summary: Mock, project officer, Unstable An- pranolol works in a complex man- the University of Miami. • Mortality was low and equal g-inal Trial, NHLBI; Dr. C. Richard ner, not entirely understood, to in both groups; Conti, University of Florida; Dr. reduce both the heart rate and the passes oxygen carrying blood • Myocardial infarctions oc- Adolph M. Hutter, Massachusetts force of the contractions of the around a narrowing in a coronary curred more often in the surgi- General Hospital; and Dr. Richard heart muscle, reducing the require- artery. cally treated group than in the O. Russell, University of Alabama. ment for oxygen used by the heart Careful follow-up studies on pa- medically treated group; The conservative approach to muscle per unit of time and estab- tients in both groups—in-hospital • The medical group had more treatment of unstable angina in- lishing a more normal balance be- and during the post-hospital phase persistent angina than the surgical cludes hospitalization of the pa- tween oxygen supply and demand. —included, apart from routine group. tient with bed rest and constant In the late 1960's the technique physical examinations, resting elec- The clinical investigators con- monitoring of the EKG. of coronary artery by-pass surgery trocardiograms, chest X-ray films, cluded that patients presenting was introduced. This operation was and graded exercise tolerance tests with unstable angina may be safely Nitrates Dilate developed to mechanically reestab- at 6 months and 12 months. treated with careful intensive Medication in the form of vari- lish a more normal blood supply to The results of the study revealed pharmacologic therapy. ous types of nitrates are frequently areas of heart muscle beyond ob- that mortality was comparable and Those with persistent pain may used because of their ability to structed areas in the coronary low in both groups in the hospital be studied by coronary angiogra- cause a dilating effect on blood artery system. (medical mortality 4.1 percent, phy, and those patients with left vessels. This benefits the oxygen In the coronary by-pass graft surgical 5.0 percent) and in the main coronary artery obstruction starved heart muscle in two ways. procedure the surgeon removes an post-hospital phase, with average and continued intractable pain may Generalized peripheral vascular expendable unobstructed vessel follow-up of 24 months (medical require surgery. Otherwise, pro- dilatation causes a decreased work- from the patient's own body—most mortality 5.0 percent, surgical mor- phylactic surgery to prevent a load on the heart indirectly; and commonly the saphenous vein in tality 5.2 percent). myocardial infarction or death is by direct dilatation of the coronary the leg—and uses this to form a Surgery Increases Incidence not necessary. arteries, the amount of oxygenated new conduit from the aorta to a During the in-hospital period the About one-half of the patients blood delivered to the heart muscle site in the coronary vascular tree surgically treated patients had a who suffer an acute heart attack is increased. beyond the narrowing. By this higher incidence of myocardial in- reveal—on careful questioning— Another medication often used method the surgeon detours or by- farction, 18 percent, compared to an incidence rate of 10 percent in the medically treated group. M Most of the myocardial infarc- tions in the surgically treated group were perioperative in that they occurred in relationship to the surgical procedure. In the post-hospital phase of the study, with an average follow-up of 24 months, the incidence rate of myocardial infarction was equal in the medically treated and surgi- cally treated groups (13 percent). In evaluating post-hospital an- gina pain, 15 percent of the sur- gically treated patients were re- ported to have Class III or IV angina during at least one follow- Members of the Student Government Council were intro- treasurer. Neil French, a UMC graduate, showed color up compared to 45 percent of the duced March 1 8 to students in the Upward Mobility Col- slides of his recent trip to China, sponsored by the Founda- medical group. I lege when all Upward Mobility College students met. tion for Advanced Education in the Sciences. Mr. French, However, the general assessment Members of the Student Government Council were intro- a staff technologist in the Clinical Center Radiology De- of angina is difficult to evaluate . duced. L to r, top row: Jill Fought, Robert Chames, Robert partment, was among 19 medical personnel—no physicians post-surgery for several reasons, LitHejohn, Lulie Terry, Guy Johnson, Carolyn Coleman, —invited by the Chinese government. The month-long tour including the placebo effect of Richard Munford, Carole Brown (Parklawn campus Student to Peking, Nanking, Wushi, Shanghai, Palating, Kwang- surgery. Government president) and James Toliver. Bottom row, chow, and Shumcum included medical facilities, tourist Eight medical centers partici- I to r: Susan Harwood, assistant secretary; Calvin Bussey, attractions, and visits with families in their homes. Mrs. pate in the Myocardial Infarction vice president; Delores Nolanjd, secretary; Cecil Grandy, Molly Schuchet, one of Mr. French's UMC instructors, Research Units with NHLBI coop- parliamentarian; Ellen Gross, president; and George Martin, submitted his name for inclusion on the tour. eration and support. Page 8 April 5, 1977 THE NIH RECORD Drs. Fredrickson, Butler, and Alexander NASA Seeks Applicants NHLBI Pharmacologist Dr. Jerry Mitchell Is Address Minority Biomedical Symposium For Astronaut Program Abel Award Recipient The National Aeronautics and Space Administration (NASA) has Dr. Jerry R. Mitchell, chief of announced the availability of a the Section on Clinical Pharma- minimum of 15 astronaut (mission cology and Metabolism in the Na- specialist) candidate positions at tional Heart, Lung, and Blood the Lyndon B. Johnson Space Cen- Institute, is the recipient of the ter in Houston, Tex. 1977 John J. Abel Award in These positions are available to Pharmacology. individuals with backgrounds in en- The award, presented each year gineering and the sciences. in recognition of original and out- Successful applicants will be standing research in the field of placed in responsible technical or pharmacology and/or experimental scientific positions for a period of threapeutics, is sponsored by Eli up to 2 years, receiving assign- Lilly and Company, Indianapolis. Dr. Fredrickson (I) will address symposium participants, concerning the com- ments allowing them to contribute Presented In Chicago mitment of NIH to providing opportunities for minorities in biomedical research. substantially to the Shuttle Pro- Candidates are selected by the Dr. Robert N. Butler (c). Director of the National Institute on Aging, the detail gram and to continue work in their some of the special problems of aging among minorities and will discuss access American Society for Pharmacol- scientific or technical fields. ogy and Experimental Therapeut- to careers in geriatric medicine for minority members. Dr. Benjamin Alexander They will also be enrolled in the ics. Dr. Mitchell will receive the (r), president of Chicago State University and former program chief of the MBS basic astronaut training program award April 6 in Chicago at the Program, will present the topic. Will Man Survive His Polluted Environment, allowing development of back- Society's spring meeting during the including over-population and the strain placed on the earth's water supply. ground knowledge and skills that FASEB convention. Dr. Donald Fredrickson, Director of NIH, will be the keynote speaker will be required for their formal He was cited for his research on at the Fifth Annual Minority Biomedical Support (MBS) Program- mission training upon selection for Xavier University Symposium in New Orleans, April 11-13. their first flight. Approximately 1,200 biomedical Selection as astronaut candidates researchers of minority origin— of the Harvard Medical School; does not insure selection as astro- Black, Spanish-speaking, American Dr. Luis Gabriel Navar of the Uni- nauts. Final selection will depend Indian, and Hawaiian/Polynesian versity of Alabama Medical Center; on satisfactory completion of the —are expected to attend the sym- Dr. Richard Lumsden of Tulane 2-year evaluation period. posium, making it the largest mi- University; Dr. Edward Haw- Applicants must have at least a nority biomedical research meeting. thorne, dean of Howard University bachelor's and preferably an ad- The symposium is co-sponsored Graduate School, and Dr. Charles vanced degree in engineering, bio- by New Orleans' Xavier University Proctor of Meharry Med. College. logical or physical science, or of Louisiana and the Division of mathematics. Research Resources, through its Minority Biomedical Support Pro- Women, Minorities May Apply gram. Women and minority candidates are encouraged to apply. Began in 1972 For further information write The MBS Program, launched by to: Astronaut (Mission Specialist) Dr. Mitchell's other honors have in- DRR in 1972, is intended to en- Candidate Program, Code AHX, cluded the Borden Medical Research courage increased involvement of NASA Johnson Space Center, Award at Vanderbilt University. In ethnic minority students and fac- Houston, Tex. 77058. April 1976 he served as the William ulty in the biomedical sciences and The closing date for filing for N. Creasy-Burroughs Wellcome Visit- health professions. these positions is June 30, 1977. ing Professor at the Albert Einstein The funding allows grantee in- College of Medicine. stitutions to purchase necessary active substances, some of them laboratory equipment, to free fac- Thousands Are Participating highly toxic to the liver, kidney, ulty scientists for research by hir- In FASEB Meeting in Chicago and other organs. ing additional teachers, to conduct The largest scientific meeting in Many therapeutic agents owe research programs, to pay the the world—the 61st Annual Meet- their effectiveness to metabolites salaries of research personnel, and ing of the Federation of American produced from the parent drug by to participate in biomedical sym- Societies for Experimental Biology enzyme systems of liver micro- posia, such as the New Orleans —is being held in Chicago, April somes and possibly intracellular meeting. organelles. A student chemistry researcher at 1-8. There are now 80 colleges and Unfortunately, the same orga- universities participating in the Xavier University of Louisiana works April 4 Is NIH Night on a research project which he will nelles and the same enzymes may program. Last year, approximately On a special NIH night, Mon- be responsible for serious and occa- 1,800 researchers, including 970 report on during the symposium, the day, April 4, NIH Director Dr. largest gathering of minority bio- sionally fatal reactions to certain undergraduates, 617 faculty and Donald S. Fredrickson addressed drugs. staff members, 176 graduate stu- medical researchers. the convention. A native of Detroit, Dr. Mitchell dents, and 3 postdoctoral trainees Mr. Elward Bynum, program About 20,000 persons, including received program support. received his B.A., M.D., and Ph.D. chief of the Minority Access to 15,000 biomedical researchers will in pharmacology from Vanderbilt U. At this year's symposium, at the Research Careers (MARC) Pro- attend, and more than 5,600 papers Fountainebleau Motor Hotel, about After residency training in in- gram, National Institute of Gen- will be presented. ternal medicine, at the New York 100 universities and colleges will be eral Medical Sciences, will describe Approximately 650 exhibits at represented. Hospital-Cornell Medical Center, the MARC Program which awards McCormick Place will represent he joined the scientific staff of the Approximately 350 scientific re- individual and institutional fellow- some 370 organizations. NHLBI Laboratory of Chemical search papers will be presented in ships to minorities for predoctoral FASEB is a nonprofit scientific Pharmacology in 1970. He served biochemistry, microbiology, chem- and postdoctoral training. organization to develop and dis- for 3 years as chief of its Section istry, physiology, pharmacology, The symposium is being organ- seminate new knowledge in the life on Clinical Pharmacology before parasitology, and other biomedical ized and administered by Dr. Joyce sciences through its annual meet- assuming his present position in research areas, most by student- Corrington, director of Research in ings and publications, principally the Institute's Office of the Director researchers. Science for Xavier University, and Federation Proceedings. for Intramural Research in 1976. Well-known scientists presenting Dr. Ciriaco Gonzales, MBS pro- papers include: Dr. Harold Amos gram director, DRR. •& U.S. GOVERNMENT PRINTING OFFICE: 1977 341-163/12