(12) Patent Application Publication (10) Pub. No.: US 2014/0227686 A1 Saghbini Et Al
US 20140227686A1 (19) United States (12) Patent Application Publication (10) Pub. No.: US 2014/0227686 A1 Saghbini et al. (43) Pub. Date: Aug. 14, 2014 (54) STABILIZED CHEMICAL DEHYDRATION OF Publication Classification BOLOGICAL MATERAL (51) Int. Cl. (71) Applicant: GENTEGRALLC, Pleasanton, CA CI2O I/68 (2006.01) (US) (52) U.S. Cl. CPC .................................... CI2O I/6806 (2013.01) (72) Inventors: Michael Saghbini, Poway, CA (US); USPC ........................................................... 435/6.1 Michael Hogan, Tucson, AZ (US); Chunnian Shi, San Diego, CA (US); (57) ABSTRACT Brian Dalby, Carlsbad, CA (US); David Wong, San Marcos, CA (US) The present invention provides compositions and methods that enable the stabilization and storage of samples by con (73) Assignee: GENTEGRALLC, Pleasanton, CA tacting a sample with an assembly of particles, and reducing (US) the water activity level of the contacted sample. By reducing the water activity level of the sample, the assembly of par (21) Appl. No.: 14/254,478 ticles minimizes the degradation of the sample. Stabilizers may or may not be added to the assembly of particles to (22) Filed: Apr. 16, 2014 further minimize the degradation of the sample. Subsequently to storage in the assembly of particles, the samples are recov Related U.S. Application Data erable by eluting the assembly of particles with a fluid solu tion. In one embodiment, the entire assembly of particles will (63) y apps No. 13/081,436, filed on dissolve into the solution. In another embodiment, only part pr. o. s of the assembly of particles will dissolve into the solution. (60) Provisional application No. 61/321,269, filed on Apr.
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