DOCSLIB.ORG

JMPR/WHO Report 1999

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
JMPR/WHO Report 1999 iii CONTENTS PARTICIPANTS ..................................................................................................................... v ABBREVIATIONS ................................................................................................................ xv USE OF JMPR REPORTS AND EVALUATIONS BY REGISTRATION AUTHORITIES ......................................................................................................................xix 1. INTRODUCTION ............................................................................................................... 1 2. GENERAL CONSIDERATIONS ....................................................................................... 3 2.1. Increasing workload of JMPR participants..............................................................3 2.2 Maximum residue limits for monitoring (MRLM)..................................................4 2.3. Consideration of recommendations arising from the informal JMPR/JECFA harmonization meeting (February 1999, Rome)..................................................... 6 2.4 Progress on acute dietary intake estimation-International Estimate of Short Term Dietary Intake (IESTI) .................................................................................. 9 2.5 OECD Working Group on Pesticides - Workshop on developing minimum residue data requirements for estimating MRLs and import tolerances11 2.6 Issues affecting studies of the effects of processing on residues 12 2.7 Sensitivity of infants and children to pesticides16 2.8 Relevance of pesticide specifications for JMPR evaluations ................................16 2.9 Statistical evaluation of residues data17 2.10 Periodic review of residue data for compounds currently under national re- registration .............................................................................................................18 3. DIETARY RISK ASSESSMENT FOR PESTICIDE RESIDUES IN FOOD ....................21 4. EVALUATION OF DATA FOR ADIs FOR HUMANS, MAXIMUM RESIDUE LEVELS, STMR LEVELS AND DAILY INTAKES 1 .................................................... 27 4.1 Bentazone (R) ....................................................................................................... 27 4.2 Bitertanol** (R).....................................................................................................28 4.3 Bufrofezin (R)........................................................................................................39 4.4 Carbofuran (R)...................................................................................................... 44 4.5 Carbosulfan (R) .....................................................................................................46 4.6 Chlormequat (Acute RfD)..................................................................................... 47 4.7 Chlorpyrifos** (T)................................................................................................ 48 4.8 Clethodim (R)........................................................................................................55 4.9 Diazinon (R)..........................................................................................................60 ________________________________ 1 T= Toxicology * New compound R= Residue and analytical aspects ** Evaluation in CCPR periodic review programme E = Evaluation of effects on the environment iv 4.10 Dimethipin**(T)64 4.11 Dinocap 1(T, R)69 4.12 Ethephon (R)73 4.13 Ethoprophos **(T)78 4.14 Ethoxyquin** (R)83 4.15 Fenamiphos **(R) 87 4.16 Fenpropimorph (R)103 4.17 Fenpyroximate (R)108 4.18 Folpet (R)114 4.19 Glufosinate-ammonium (T, R)121 4.20 Malathion **(R)129 4.21 Methiocarb **(R)144 4.22 Oxydemeton methyl (R) 156 4.23 Permethrin ** (T) 157 4.24 2-Phenylphenol **(T,R)162 4.25 Phosalone (R)172 4.26. Propargite **(T)...................................................................................................176 4.27. Propylenethiourea(T) ...........................................................................................181 4.28. Pyrethrum extract **(Pyrethrins) (T) ..................................................................183 4.29. Pyriproxyfen* (T, R)............................................................................................188 4.30. Tebufenozide (R) .................................................................................................200 5. RECOMMENDATIONS203 6. FUTURE WORK...............................................................................................................205 6.1 2000 Meeting205 6.2 2001 Meeting206 7. REFERENCES ..................................................................................................................207 CORRECTIONS TO REPORT OF 1998 JMPR ...................................................................215 ANNEX I: ADIs, acute RfDs, recommended MRLs, STMRs, GLs .....................................217 ANNEX II: Index of reports and evaluations ........................................................................229 ANNEX III: Dietary intakes of pesticides in relation to ADIs..............................................243 ANNEX IV: Estimates of acute dietary intake ....................................................................267 ANNEX V: Draft report of an ad- hoc expert meeting on acute dietary intake of pesticide residues ........................ .....................................................................289 ________________________________ 1Evaluated in 1998 JMPR but omitted from the report v 1999 Joint FAO/WHO Meeting on Pesticide Residues Rome, 20-29 September 1999 PARTICIPANTS WHO Members Professor A.R. Boobis Section on Clinical Pharmacology Division of Medicine Imperial College School of Medicine Hammersmith Campus Ducane Road London W12 0NN UK Tel: (44 20) 383 3221 Fax: (44 20) 383 2066 E-mail: [email protected] Professor Joseph F. Borzelleca (Vice-chairman) Dept. of Pharmacology & Toxicology Virginia Commonwealth University Medical College of Virginia (H) 8718 September Drive Richmond VA 23229-7319 USA Tel: (001) 804 285 2004 Fax: (001) 804 285 1401 E-mail: [email protected] Dr Penelope Fenner-Crisp Senior Science Advisor to the Director Office of Pesticide Programs (750/C) US Environmental Protection Agency 401 M Street, S.W. Washington, D.C. 20460 USA Tel: (1 703) 605 0654 Fax: (1 703) 308 4776 E-mail: [email protected] vi Participants Dr A. Moretto Istituto di Medicina del Lavoro Università di Padova Via Giustiniani 2 35128 Padova Italy Tel: (39 049) 821 2549/1 Fax: (39 049) 821 2550 E-mail: [email protected] Professor Olavi Pelkonen Department of Pharmacology and Toxicology University of Oulu P.O. Box 5000 (Kajaanintie 52D) 90401 Oulu Finland Tel: (358 8) 537 5230 Fax: (358 8) 537 5247 E-mail: [email protected] Dr Brian G. Priestly (Rapporteur) Scientific Director Chemicals & Non-Prescription Medicines Branch Therapeutic Goods Administration Commonwealth Department of Health and Aged Care P.O. Box 100 Woden, ACT 2606 Australia Tel: (61 2) 6289 7040 Fax: (61 2) 6289 7211 E-mail: [email protected] Professor Salah A. Soliman Department of Pesticide Chemistry Faculty of Agriculture Alexandria University El-Shatby Alexandria 21545 Egypt Tel: (203) 544 8403 or 455 1500 Fax: (203) 481 7232 or 597 2780 E-mail: Participants vii FAO Members Dr Ursula Banasiak Federal Biological Research Centre for Agriculture and Forestry Stahnsdorfer Damm 81 14532 Kleinmachnow Germany Tel: (49 33203) 48338 Fax: (49 33203) 48425 E-mail: [email protected] Dr Eloisa Dutra Caldas (Rapporteur) University of Brasilia College of Health Sciences Pharmaceutical Sciences Department Campus Universitàrio Darci Ribeiro 70919-970 Brasília/DF Brazil Tel: (55 61) 316 9825 Fax: (55 61) 321-9995 E-mail: [email protected] Dr Stephen Funk Health Effects Division (7509C) US Environmental Protection Agency 401 M Street, S.W. Washington, D.C. 20460 USA Tel: (1 703) 305 5430 Fax: (1 703) 305-5147/5529 E-mail: [email protected] Mr D.J. Hamilton (Chairman) Principal Scientific Officer Animal & Plant Health Service, Floor 3PIB Department of Primary Industries P.O. Box 46 Brisbane, QLD 4001 Australia Tel: (61 7) 3239 3409 Fax: (61 7) 3211 3293 E-mail: [email protected] viii Participants Secretariat Dr Arpad Ambrus Head, Agrochemicals Unit Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture IAEA Wagramer Strasse 5, P.O. Box 100 A-1400 Vienna Austria Tel: (43 1) 2600 28395 Fax: (43 1) 26007 28222 E-mail: [email protected] Dr Rajumati Bhula (FAO Consultant) National Registration Authority for Agricultural and Veterinary Chemicals Chemistry and Residue Evaluation Section 22 Brisbane Avenue P.O. Box E240, Kingston, ACT 2604 Australia Tel: (61 2) 6271 6551 Fax: (61 2) 6272 3551 E-mail: [email protected] Dr Elisabeth Bosshard (WHO Temporary Adviser) Federal Office of Agriculture Section Crop Protection Products Mattenhofstrasse 5 3003 Bern Switzerland Tel: (41 31) 324 90 80 Fax: (41 31) 322 70 80 E-mail: [email protected] Dr Susan May F. Calumpang (FAO Consultant) National Crop Protection Center University of the Philippines Los Baños, Laguna Philippines Tel: (63) 49 536 2231/49 536 0983 Fax: (63) 49 536 2409 E-mail: [email protected] Participants ix Dr Ian C. Dewhurst (WHO Temporary Adviser) Pesticides Safety Directorate Ministry of Agriculture, Fisheries and Food Mallard House King’s Pool 3 Peasholme Green York YO1 7PX UK Tel: (44 1904) 455 890 Fax: (44 1904) 455 711 E-mail:
Load more

Recommended publications
  • Cypermethrin
    International Environmental Health Criteria 82 Cypermethrin Published under the joint sponsorship of the United Nations Environment Programme, the International Labour Organisation, and the World Health Organization WORLD HEALTH ORGANIZATION GENEVA 1989 Other titles available in the ENVIRONMENTAL HEALTH CRITERIA series include: 1. Mercury 2. Polychlorinated Biphenyls and Terphenyls 3. Lead 4. Oxides of Nitrogen 5. Nitrates, Nitrites, and N-Nitroso Compounds 6. Principles and Methods for Evaluating the Toxicity of Chemicals, Part 1 7. Photochemical Oxidants 8. Sulfur Oxides and Suspended Particulate Matter 9. DDT and its Derivatives 10. Carbon Disulfide 11. Mycotoxins 12. Noise 13. Carbon Monoxide 14. Ultraviolet Radiation 15. Tin and Organotin Compounds 16. Radiofrequency and Microwaves 17. Manganese 18. Arsenic 19. Hydrogen Sulfide 20. Selected Petroleum Products 21. Chlorine and Hydrogen Chloride 22. Ultrasound 23. Lasers and Optical Radiation 24. Titanium 25. Selected Radionuclides 26. Styrene 27. Guidelines on Studies in Environmental Epidemiology 28. Acrylonitrile 29. 2,4-Dichlorophenoxyacetic Acid (2,4-D) 30. Principles for Evaluating Health Risks to Progeny Associated with Exposure to Chemicals during Pregnancy 31. Tetrachloroethylene 32. Methylene Chloride 33. Epichlorohydrin 34. Chlordane 35. Extremely Low Frequency (ELF) Fields 36. Fluorine and Fluorides 37. Aquatic (Marine and Freshwater) Biotoxins 38. Heptachlor 39. Paraquat and Diquat 40. Endosulfan 41. Quintozene 42. Tecnazene 43. Chlordecone 44. Mirex continued on p. 156
    [Show full text]
  • Historical Perspectives on Apple Production: Fruit Tree Pest Management, Regulation and New Insecticidal Chemistries
    Historical Perspectives on Apple Production: Fruit Tree Pest Management, Regulation and New Insecticidal Chemistries. Peter Jentsch Extension Associate Department of Entomology Cornell University's Hudson Valley Lab 3357 Rt. 9W; PO box 727 Highland, NY 12528 email: [email protected] Phone 845-691-7151 Mobile: 845-417-7465 http://www.nysaes.cornell.edu/ent/faculty/jentsch/ 2 Historical Perspectives on Fruit Production: Fruit Tree Pest Management, Regulation and New Chemistries. by Peter Jentsch I. Historical Use of Pesticides in Apple Production Overview of Apple Production and Pest Management Prior to 1940 Synthetic Pesticide Development and Use II. Influences Changing the Pest Management Profile in Apple Production Chemical Residues in Early Insect Management Historical Chemical Regulation Recent Regulation Developments Changing Pest Management Food Quality Protection Act of 1996 The Science Behind The Methodology Pesticide Revisions – Requirements For New Registrations III. Resistance of Insect Pests to Insecticides Resistance Pest Management Strategies IV. Reduced Risk Chemistries: New Modes of Action and the Insecticide Treadmill Fermentation Microbial Products Bt’s, Abamectins, Spinosads Juvenile Hormone Analogs Formamidines, Juvenile Hormone Analogs And Mimics Insect Growth Regulators Azadirachtin, Thiadiazine Neonicotinyls Major Reduced Risk Materials: Carboxamides, Carboxylic Acid Esters, Granulosis Viruses, Diphenyloxazolines, Insecticidal Soaps, Benzoyl Urea Growth Regulators, Tetronic Acids, Oxadiazenes , Particle Films, Phenoxypyrazoles, Pyridazinones, Spinosads, Tetrazines , Organotins, Quinolines. 3 I Historical Use of Pesticides in Apple Production Overview of Apple Production and Pest Management Prior to 1940 The apple has a rather ominous origin. Its inception is framed in the biblical text regarding the genesis of mankind. The backdrop appears to be the turbulent setting of what many scholars believe to be present day Iraq.
    [Show full text]
  • Determination of Age-Related Differences in Activation and Detoxication of Organophosphates in Rat and Human Tissues
    Mississippi State University Scholars Junction Theses and Dissertations Theses and Dissertations 8-10-2018 Determination of Age-Related Differences in Activation and Detoxication of Organophosphates in Rat and Human Tissues Edward Caldwell Meek Follow this and additional works at: https://scholarsjunction.msstate.edu/td Recommended Citation Meek, Edward Caldwell, "Determination of Age-Related Differences in Activation and Detoxication of Organophosphates in Rat and Human Tissues" (2018). Theses and Dissertations. 1339. https://scholarsjunction.msstate.edu/td/1339 This Dissertation - Open Access is brought to you for free and open access by the Theses and Dissertations at Scholars Junction. It has been accepted for inclusion in Theses and Dissertations by an authorized administrator of Scholars Junction. For more information, please contact [email protected]. Template A v3.0 (beta): Created by J. Nail 06/2015 Determination of age-related differences in activation and detoxication of organophosphates in rat and human tissues By TITLE PAGE Edward Caldwell Meek A Dissertation Submitted to the Faculty of Mississippi State University in Partial Fulfillment of the Requirements for the Degree of Doctor of Philosophy in Environmental Toxicology in the College of Veterinary Medicine Mississippi State, Mississippi August 2018 Copyright by COPYRIGHT PAGE Edward Caldwell Meek 2018 Determination of age-related differences in activation and detoxication of organophosphates in rat and human tissues By APPROVAL PAGE Edward Caldwell Meek
    [Show full text]
  • 1 Chiral Analysis of Pollutants and Their Metabolites by Capillary
    View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by Digital.CSIC Chiral analysis of pollutants and their metabolites by capillary electromigration methods Javier Hernández-Borges1, Miguel Ángel Rodríguez-Delgado1, Francisco J. García-Montelongo1, Alejandro Cifuentes2,* 1Department of Analytical Chemistry, Nutrition and Food Science, University of La Laguna, Avda. Astrofísico Fco. Sánchez s/n, 38071 La Laguna, Tenerife, Spain. 2 Department of Food Analysis, Institute of Industrial Fermentations (CSIC), Juan de la Cierva 3, 28006 Madrid, Spain. Keywords: capillary electrophoresis; enantiomers; pollutants; pesticides; review; chiral analysis; CE; MEKC; CEC. Corresponding author: Dr. Alejandro Cifuentes E-mail: [email protected] Fax: +34-91-5644853; Tel: +34-91-5622900 1 Abbreviations: allyl-TER: 1-allylterguride; ANDSA: 7-aminonaphthalene-1,3-disulfonic acid; ANSA: 5-aminonaphthalene-1-sulfonic acid; ANTS: 8-aminonaphthalene-1,3,6-trisulfonic acid; BGE: background electrolyte; CM-γ-CD: carboxymethylated-γ-cyclodextrin; MCPA: (4-chloro-2-methylphenoxy)-acetic acid; MCPB: (4-chloro-2-methylphenoxy)butyric acid; 2,2-CPPA: 2-(2-chlorophenoxy)-propionic acid; 2,3-CPPA: 2-(3- chlorophenoxy)propionic acid; 2,4-CPPA: 2-(4-chlorophenoxy)-propionic acid; CMBA: 2-(4-chlorophenyl)-3-methylbutanoic acid; CA: chrysanthemic acid; MEGA: decanoyl-N-methylglucamide; DCA: dichorochrysanthemic acid; 2,4-D: (2,4- dichlorophenoxy)acetic acid; 2,4-DB: 4-(2,4-dichlorophenoxy)butiric acid; 2,4- DCPPA: 2-(2,4-dichlorophenoxy)propionic
    [Show full text]
  • Manual for Certificate Course on Plant Protection & Pesticide Management
    Manual for Certificate Course on Plant Protection & Pesticide Management (for Pesticide Dealers) For Internal circulation only & has no legal validity Compiled by NIPHM Faculty Department of Agriculture , Cooperation& Farmers Welfare Ministry of Agriculture and Farmers Welfare Government of India National Institute of Plant Health Management Hyderabad-500030 TABLE OF CONTENTS Theory Practical CHAPTER Page No. class hours hours I. General Overview and Classification of Pesticides. 1. Introduction to classification based on use, 1 1 2 toxicity, chemistry 2. Insecticides 5 1 0 3. fungicides 9 1 0 4. Herbicides & Plant growth regulators 11 1 0 5. Other Pesticides (Acaricides, Nematicides & 16 1 0 rodenticides) II. Pesticide Act, Rules and Regulations 1. Introduction to Insecticide Act, 1968 and 19 1 0 Insecticide rules, 1971 2. Registration and Licensing of pesticides 23 1 0 3. Insecticide Inspector 26 2 0 4. Insecticide Analyst 30 1 4 5. Importance of packaging and labelling 35 1 0 6. Role and Responsibilities of Pesticide Dealer 37 1 0 under IA,1968 III. Pesticide Application A. Pesticide Formulation 1. Types of pesticide Formulations 39 3 8 2. Approved uses and Compatibility of pesticides 47 1 0 B. Usage Recommendation 1. Major pest and diseases of crops: identification 50 3 3 2. Principles and Strategies of Integrated Pest 80 2 1 Management & The Concept of Economic Threshold Level 3. Biological control and its Importance in Pest 93 1 2 Management C. Pesticide Application 1. Principles of Pesticide Application 117 1 0 2. Types of Sprayers and Dusters 121 1 4 3. Spray Nozzles and Their Classification 130 1 0 4.
    [Show full text]
  • Genetically Modified Baculoviruses for Pest
    INSECT CONTROL BIOLOGICAL AND SYNTHETIC AGENTS This page intentionally left blank INSECT CONTROL BIOLOGICAL AND SYNTHETIC AGENTS EDITED BY LAWRENCE I. GILBERT SARJEET S. GILL Amsterdam • Boston • Heidelberg • London • New York • Oxford Paris • San Diego • San Francisco • Singapore • Sydney • Tokyo Academic Press is an imprint of Elsevier Academic Press, 32 Jamestown Road, London, NW1 7BU, UK 30 Corporate Drive, Suite 400, Burlington, MA 01803, USA 525 B Street, Suite 1800, San Diego, CA 92101-4495, USA ª 2010 Elsevier B.V. All rights reserved The chapters first appeared in Comprehensive Molecular Insect Science, edited by Lawrence I. Gilbert, Kostas Iatrou, and Sarjeet S. Gill (Elsevier, B.V. 2005). All rights reserved. No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publishers. Permissions may be sought directly from Elsevier’s Rights Department in Oxford, UK: phone (þ44) 1865 843830, fax (þ44) 1865 853333, e-mail [email protected]. Requests may also be completed on-line via the homepage (http://www.elsevier.com/locate/permissions). Library of Congress Cataloging-in-Publication Data Insect control : biological and synthetic agents / editors-in-chief: Lawrence I. Gilbert, Sarjeet S. Gill. – 1st ed. p. cm. Includes bibliographical references and index. ISBN 978-0-12-381449-4 (alk. paper) 1. Insect pests–Control. 2. Insecticides. I. Gilbert, Lawrence I. (Lawrence Irwin), 1929- II. Gill, Sarjeet S. SB931.I42 2010 632’.7–dc22 2010010547 A catalogue record for this book is available from the British Library ISBN 978-0-12-381449-4 Cover Images: (Top Left) Important pest insect targeted by neonicotinoid insecticides: Sweet-potato whitefly, Bemisia tabaci; (Top Right) Control (bottom) and tebufenozide intoxicated by ingestion (top) larvae of the white tussock moth, from Chapter 4; (Bottom) Mode of action of Cry1A toxins, from Addendum A7.
    [Show full text]
  • ACTION: Original DATE: 08/20/2020 9:51 AM
    ACTION: Original DATE: 08/20/2020 9:51 AM TO BE RESCINDED 3745-100-10 Applicable chemicals and chemical categories. [Comment: For dates of non-regulatory government publications, publications of recognized organizations and associations, federal rules, and federal statutory provisions referenced in this rule, see paragraph (FF) of rule 3745-100-01 of the Administrative Code titled "Referenced materials."] The requirements of this chapter apply to the following chemicals and chemical categories. This rule contains three listings. Paragraph (A) of this rule is an alphabetical order listing of those chemicals that have an associated "Chemical Abstracts Service (CAS)" registry number. Paragraph (B) of this rule contains a CAS registry number order list of the same chemicals listed in paragraph (A) of this rule. Paragraph (C) of this rule contains the chemical categories for which reporting is required. These chemical categories are listed in alphabetical order and do not have CAS registry numbers. (A) Alphabetical listing: Chemical Name CAS Number abamectin (avermectin B1) 71751-41-2 acephate (acetylphosphoramidothioic acid o,s-dimethyl ester) 30560-19-1 acetaldehyde 75-07-0 acetamide 60-35-5 acetonitrile 75-05-8 acetophenone 98-86-2 2-acetylaminofluorene 53-96-3 acifluorfen, sodium salt [5-(2-chloro-4-(trifluoromethyl)phenoxy)-2- 62476-59-9 nitrobenzoic acid, sodium salt] acrolein 107-02-8 acrylamide 79-06-1 acrylic acid 79-10-7 acrylonitrile 107-13-1 [ stylesheet: rule.xsl 2.14, authoring tool: RAS XMetaL R2_0F1, (dv: 0, p: 185720, pa:
    [Show full text]
  • (12) United States Patent (10) Patent No.: US 8,852,618 B2 Clough (45) Date of Patent: Oct
    USOO8852618B2 (12) United States Patent (10) Patent No.: US 8,852,618 B2 Clough (45) Date of Patent: Oct. 7, 2014 (54) INSECTICIDAL MIXTURE CONTAINING CA 2429218 A1 6, 2002 GAMMA-CYHALOTHRN CH 689326 A5 4f1995 EP O237227 A1 9, 1987 EP 0771526 A2 5, 1997 (75) Inventor: Martin Stephen Clough, Bracknell EP O988788 A1 3f2000 (GB) FR 272O230 A1 12/1995 JP 63. 126805 A2 5, 1988 (73) Assignee: Syngenta Limited, Guildford (GB) JP 63126805 A2 5, 1988 JP 63126805 5, 1998 c - r WO WO 86 O7525 A1 12, 1986 (*) Notice: Subject to any disclaimer, the term of this WO WO 93 03618 A2 3, 1993 patent is extended or adjusted under 35 WO WO95 229O2 A1 8/1995 U.S.C. 154(b) by 824 days. WO WO9533380 A1 12, 1995 WO WO 96 16543 A2 6, 1996 (21) Appl. No.: 12/633,063 WO WO97 06687 A1 2/1997 WO WO974O692 A1 11, 1997 (22) Filed: Dec.a V88, 2009 WO WOOOO2453 A1 1, 2000 OTHER PUBLICATIONS (65) Prior Publication Data US 201O/OO81714 A1 Apr. 1, 2010 Canadian Office Action (Applin. No. 2,452,515 filed: Jul. 10, 2002) mailing date Oct. 1, 2010 (pp. 1-2). Related U.S. Application Data Allen et al. Transgenic & Conventional Insect & Weed Control Sys tems; Proceedings of the Beltwide Cotton Conference, vol. 2, 1065 (62) Division of application No. 10/484.745, filed as 1068 (1999), USA. application No. PCT/GB02/03181 on Jul. 10, 2002, Anonymous; Pesticide Mixtures for Control of Insect and Acarid now Pat. No.
    [Show full text]
  • 20110628140658587.Pdf
    1210 YUE ET AL.:JOURNAL OF AOAC INTERNATIONAL VOL. 91, NO. 5, 2008 SPECIAL GUEST EDITOR SECTION High-Performance Thin-Layer Chromatographic Analysis of Selected Organophosphorous Pesticide Residues in Tea YONGDE YUE International Center for Bamboo and Rattan, 100102, Beijing, People’s Republic of China RONG ZHANG and WEI FAN Key Laboratory for Agri-Food Safety of Anhui Province, School of Resources and Environment, Anhui Agricultural University, Hefei, Anhui, 230036, People’s Republic of China FENG TANG International Center for Bamboo and Rattan, 100102, Beijing, People’s Republic of China The separation of 9 organophosphates determination procedure. In many cases, searching for a fast (monocrotophos, quinalphos, triazophos, and efficient method for enrichment and determination of parathion-methyl, isofenphos-methyl, temephos, organophosphorous residues from complex matrixes is still a parathion, phoxim-ethyl, and chlorpyrifos) by challenge for many researchers. high-performance thin-layer chromatography In many analytical situations, modern quantitative (HPTLC) with automated multiple development was high-performance thin-layer chromatography (HPTLC), studied. The HPTLC method was developed and when properly performed by well-trained analysts, has many validated for analysis of residues of phoxim-ethyl advantages over HPLC or GC. These advantages include and chlorpyrifos in tea. The sample was extracted simplicity of operation, the availability of many sensitive and with acetonitrile and cleaned up by ENVI-CARB selective reagents for detection and confirmation without solid-phase extraction. The extract was directly interference from the mobile phase, the ability to repeat applied as bands to glass-backed silica gel 60F254 detection and quantification at any time with changed HPTLC plates.
    [Show full text]
  • Assessing the Single and Combined Toxicity of Chlorantraniliprole And
    toxins Article Assessing the Single and Combined Toxicity of Chlorantraniliprole and Bacillus thuringiensis (GO33A) against Four Selected Strains of Plutella xylostella (Lepidoptera: Plutellidae), and a Gene Expression Analysis Muhammad Zeeshan Shabbir 1,2, Ling He 1,2, Changlong Shu 3, Fei Yin 1,2, Jie Zhang 3 and Zhen-Yu Li 1,2,* 1 Institute of Plant Protection, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China; [email protected] (M.Z.S.); [email protected] (L.H.); [email protected] (F.Y.) 2 Guangdong Provincial Key Laboratory of High Technology for Plant Protection, Guangzhou 510640, China 3 State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100094, China; [email protected] (C.S.); [email protected] (J.Z.) * Correspondence: [email protected] Abstract: Concerns about resistance development to conventional insecticides in diamondback moth (DBM) Plutella xylostella (L.), the most destructive pest of Brassica vegetables, have stimulated interest in alternative pest management strategies. The toxicity of Bacillus thuringiensis subsp. aizawai (Bt GO33A) combined with chlorantraniliprole (Chl) has not been documented. Here, we examined sin- gle and combined toxicity of chlorantraniliprole and Bt to assess the levels of resistance in four DBM strains. Additionally, enzyme activities were tested in field-original highly resistant (FOH-DBM), Bt-resistant (Bt-DBM), chlorantraniliprole-resistant (CL-DBM), and Bt + chlorantraniliprole-resistant (BtC-DBM) strains. The Bt product had the highest toxicity to all four DBM strains followed by the Citation: Shabbir, M.Z.; He, L.; Shu, mixture of insecticides (Bt + Chl) and chlorantraniliprole.
    [Show full text]
  • Sister Chromatid Exchanges Induced by the Organophosphorus Insecticides Methyl Parathion, Dimethoate, Phoxim and Methyl Azinfos in Cultured Human Lymphocytes
    Contam. Arnbient. 3. 63-70. 1981 SISTER CHROMATID EXCHANGES INDUCED BY THE ORGANOPHOSPHORUS INSECTICIDES METHYL PARATHION, DIMETHOATE, PHOXIM AND METHYL AZINFOS IN CULTURED HUMAN LYMPHOCYTES SANDRAGOMEZ-ARROYO, NORMANORIEGA-ALDANA, DOLORESJUAREZ-RODRI- GUEZ and RAFAELVILLALOBOS-PIETRINI Laboratorio de Citogenética y Mutagénesis Ambientales, Centro de Ciencias de la Atmós- fera, Universidad Nacional Autánoma de México, Coyoacán 04510, México, D.F. México (Recibido septiembre 1987, Aceptado diciembre 1987) ABSTRACT The cytogenetic effect of the organophosphorus insecticides methyl parathion or folidol. dimethoate or rogor. phoxirn or bay 77488 and methyl azinfos or gusathion was evahiated by means of the productions of sister chromatid exchanges (SCE) in cultured human lymphocytes. Positive results were obtained with methyl parathion, dimethoate and phoxim, while a negative response was achieved with methyl azinfos. The highest con- centrations of all substances decreased the SCE. possibly due to their toxicity, produ- cing the death of the damaged cells and therefore eiiminating the SCE expression. RESUMEN Se evaluó el afecto citogenbtico de los insecticidas organofosforados metil paration o foiidol, dimetoato o rogor. foxim o bay 77488 y metil azinfos o gusation mediante el anáiisis de intercambio de cromátidas hermanas (ICH) en cultivo de linfocitos humanos. Se obtuvieron resultados positivos con metil paratión, dimetoato y foxim, en tanto que con metil azinfos la respuesta fue negativa. A las concentraciones más altas de todas las sustancias empleadas disminuyeron los ICH, debido posiblemente a su elevada to- xicidad, provocando la muerte de las células más dañadas e impidiendo de esta manera la expresión del ICH. INTRODUCTION The organophosphorus insecticides appear for the first time in 1945 in Gerrnany.
    [Show full text]
  • NASTTPO CFATS Information 2Nd Edition
    National Association of SARA Title III Program Officials Concerned with the Emergency Planning and Community Right-to-Know Act January 13, 2008 Issue 07-01 2nd Edition The Department of Homeland Security has adopted 6 CFR Part 27, a new regulation mandated by Congress, known as Chemical Facility Anti-Terrorism Standards (CFATS). The regulation is intended to fill a security gap in our country’s anti-terrorism efforts by identifying and improving the security of chemicals that are potentially at a high level of risk for release, theft, or sabotage. LEPCs and SERCs should alert EPCRA & RMP reporting facilities about these requirements. No reports are due to the LEPCs and SERCs under these requirements; however, given the potential for security requirements to have an impact on facility access for emergency responders and on emergency plans, it is critical for local planners, responders and facilities to communicate in order for a facility to satisfy the regulatory requirements. In order to aid LEPCs, SERCs and facilities in understanding these new requirements we have prepared some short-hand aids. Following this cover page is a key issue comparison between EPCRA, RMP and the CFATS regulation. As requirements may change the user is counseled to look for updated information. Following the side-by-side comparison we have edited the EPA “List of Lists” to add the Appendix A list of chemicals and thresholds from the CFATS program. This list may change and we will update these materials when that happens. The initial requirement for a facility with an Appendix A chemical at or over the threshold is to submit a Top-Screen.
    [Show full text]