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Supplementary Information for 'Effect of Common Infections on the Incidence of Post-Stroke Dementia: a Cohort Study Using

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Supplementary Information for 'Effect of Common Infections on the Incidence of Post-Stroke Dementia: a Cohort Study Using Supplementary information for ‘Effect of common infections on the incidence of post-stroke dementia: a cohort study using the Clinical Practice Research Datalink’ Contents Appendix 1: Read code lists for major infections (lower respiratory tract infection, urinary tract infection, skin and soft tissue infection) ........................................................................... 2 LRTI codelist ........................................................................................................................... 2 UTI codelist ............................................................................................................................ 7 SSTI codelist ........................................................................................................................... 9 Appendix 2: Read code list for dementia................................................................................. 15 Appendix 3: Multivariable Cox regression models for early and late dementia by all characteristics included in analysis .......................................................................................... 19 Appendix 4: Multivariable Cox regression model for sensitivity analysis excluding infections in first 3 months ....................................................................................................................... 20 Appendix 5: Multivariable Cox regression model for effect of first infection type on dementia .................................................................................................................................. 21 Appendix 1: Read code lists for major infections (lower respiratory tract infection, urinary tract infection, skin and soft tissue infection) LRTI codelist Read code Read term HYU1100 [x]acute bronchiolitis due to other specified organisms HYU1000 [x]acute bronchitis due to other specified organisms HYU0600 [x]influenza+oth respiratory manifestatns,virus not identifd HYU0700 [x]influenza+other manifestations, virus not identified HYU0500 [x]influenza+other manifestations,influenza virus identified HYU0A00 [x]other bacterial pneumonia HYU0H00 [x]other pneumonia, organism unspecified HYU0800 [x]other viral pneumonia HYU0B00 [x]pneumonia due to other specified infectious organisms HYU0C00 [x]pneumonia in bacterial diseases classified elsewhere HYU0D00 [x]pneumonia in viral diseases classified elsewhere HYU6.00 [x]suppurative & necrotic conditions of lower respir tract AYU3A00 [x]whooping cough, unspecified H530.00 abscess of lung H53..00 abscess of lung and mediastinum H53Z.00 abscess of lung and mediastinum nos H530Z00 abscess of lung nos H530300 abscess of lung with pneumonia H060X00 acute bacterial bronchitis unspecified H061.00 acute bronchiolitis H061700 acute bronchiolitis due to human metapneumovirus H061600 acute bronchiolitis due to other specified organisms H061500 acute bronchiolitis due to respiratory syncytial virus H061Z00 acute bronchiolitis nos H061200 acute bronchiolitis with bronchospasm H060.00 acute bronchitis H06..00 acute bronchitis and bronchiolitis H060B00 acute bronchitis due to coxsackievirus H060F00 acute bronchitis due to echovirus H060A00 acute bronchitis due to mycoplasma pneumoniae H060C00 acute bronchitis due to parainfluenza virus H060D00 acute bronchitis due to respiratory syncytial virus H060E00 acute bronchitis due to rhinovirus H060Z00 acute bronchitis nos H06Z.00 acute bronchitis or bronchiolitis nos H060400 acute croupous bronchitis H061300 acute exudative bronchiolitis H060800 acute haemophilus influenzae bronchitis H06Z112 acute lower respiratory tract infection H062.00 acute lower respiratory tract infection H060100 acute membranous bronchitis H060900 acute neisseria catarrhalis bronchitis H060600 acute pneumococcal bronchitis H060200 acute pseudomembranous bronchitis H060300 acute purulent bronchitis H060700 acute streptococcal bronchitis H060500 acute tracheobronchitis H060W00 acute viral bronchitis unspecified H060.11 acute wheezy bronchitis A054.00 amoebic lung abscess AB63600 aspergillus bronchitis H470.11 aspiration pneumonia H470312 aspiration pneumonia due to vomit H28..00 atypical pneumonia H29..00 avian influenza 43JQ.00 avian influenza virus nucleic acid detection H511.00 bacterial pleurisy with effusion H511Z00 bacterial pleurisy with effusion nos H22Z.00 bacterial pneumonia nos H261.00 basal pneumonia due to unspecified organism A330.00 bordetella pertussis 43WE.00 bordetella pertussis deoxyribonucleic acid detection H30Z.00 bronchitis nos H30..00 bronchitis unspecified H25..00 bronchopneumonia due to unspecified organism H07..00 chest cold H06Z011 chest infection H270.11 chest infection - influenza with pneumonia H22..11 chest infection - other bacterial pneumonia H26..11 chest infection - pnemonia due to unspecified organism H21..11 chest infection - pneumococcal pneumonia H23..11 chest infection - pneumonia organism os H30..11 chest infection - unspecified bronchitis H25..11 chest infection - unspecified bronchopneumonia H20..11 chest infection - viral pneumonia H06Z000 chest infection nos H24..11 chest infection with infectious disease ec H233.00 chlamydial pneumonia H3Y0.00 chronic obstruct pulmonary dis with acute lower resp infectn H2B..00 community acquired pneumonia Q310.00 congenital pneumonia Q310600 congenital pneumonia due to chlamydia Q310300 congenital pneumonia due to escherichia coli Q310100 congenital pneumonia due to group a haemolytic streptococcus Q310200 congenital pneumonia due to group b haemolytic streptococcus Q310400 congenital pneumonia due to pseudomonas Q310000 congenital pneumonia due to staphylococcus Q310500 congenital pneumonia due to viral agent Q310Z00 congenital pneumonia nos H564.11 cryptogenic organising pneumonia A785000 cytomegaloviral pneumonitis H22Y011 e.coli pneumonia H312100 emphysematous bronchitis H50..00 empyema H50Z.00 empyema nos H500000 empyema with bronchocutaneous fistula H500100 empyema with bronchopleural fistula H500.00 empyema with fistula H500Z00 empyema with fistula nos H501.00 empyema with no fistula H500400 empyema with pleural fistula nos H27Z.11 flu like illness H530200 gangrenous pneumonia A54X400 herpes simplex pneumonia AB40500 histoplasma capsulatum with pneumonia AB41500 histoplasma duboisii with pneumonia A789300 hiv disease resulting in pneumocystis carinii pneumonia A789311 hiv disease resulting in pneumocystis jirovecii pneumonia H2C..00 hospital acquired pneumonia 4JUF.00 human parainfluenza virus detected H540100 hypostatic bronchopneumonia H540000 hypostatic pneumonia H27..00 influenza H2A..11 influenza a (h1n1) swine flu 43W6.00 influenza a nucleic acid detection 4J3L.00 influenza a virus h1n1 subtype detected 9OXC000 influenza a virus subtype h1n1 vac inv sms text message sent 4JU4.00 influenza a virus, other or untyped strain detected 43WD.00 influenza b nucleic acid detection 4JU5.00 influenza b virus detected H2A..00 influenza due to influenza a virus subtype h1n1 4JU0.00 influenza h1 virus detected 4JU1.00 influenza h2 virus detected 4JU2.00 influenza h3 virus detected 4JU3.00 influenza h5 virus detected H27Z.12 influenza like illness H27Z.00 influenza nos H270000 influenza with bronchopneumonia H27Y000 influenza with encephalopathy H27Y100 influenza with gastrointestinal tract involvement H271000 influenza with laryngitis H27Y.00 influenza with other manifestations H27YZ00 influenza with other manifestations nos H271.00 influenza with other respiratory manifestation H271100 influenza with pharyngitis H270.00 influenza with pneumonia H270Z00 influenza with pneumonia nos H270100 influenza with pneumonia, influenza virus identified H271Z00 influenza with respiratory manifestations nos 16L..00 influenza-like symptoms H301.00 laryngotracheobronchitis H21..00 lobar (pneumococcal) pneumonia H260.00 lobar pneumonia due to unspecified organism H06Z100 lower resp tract infection H260000 lung consolidation H501300 lung empyema nos H530100 multiple lung abscess 4JUK.00 mycoplasma pneumoniae detected 65VA.00 notification of whooping cough A730.00 ornithosis with pneumonia SP13100 other aspiration pneumonia as a complication of care H22..00 other bacterial pneumonia Q310Y00 other specified congenital pneumonia H2Y..00 other specified pneumonia or influenza A33YZ00 other whooping cough nos 43JX.00 parainfluenza type 1 nucleic acid detection 43JY.00 parainfluenza type 2 nucleic acid detection 43JZ.00 parainfluenza type 3 nucleic acid detection 43W9.00 parainfluenza type 4 nucleic acid detection H501200 pleural empyema A3BY400 pleuropneumonia-like organism (pplo) infection H511000 pneumococcal pleurisy with effusion AB24.11 pneumonia - candidal H22Y200 pneumonia - legionella H2...00 pneumonia and influenza H200.00 pneumonia due to adenovirus H22YZ00 pneumonia due to bacteria nos H230.00 pneumonia due to eaton's agent H22Y000 pneumonia due to escherichia coli H222.00 pneumonia due to haemophilus influenzae H222.11 pneumonia due to haemophilus influenzae H203.00 pneumonia due to human metapneumovirus H220.00 pneumonia due to klebsiella pneumoniae H231.00 pneumonia due to mycoplasma pneumoniae H22YX00 pneumonia due to other aerobic gram-negative bacteria H22Y.00 pneumonia due to other specified bacteria H23..00 pneumonia due to other specified organisms H202.00 pneumonia due to parainfluenza virus H232.00 pneumonia due to pleuropneumonia like organisms H22Y100 pneumonia due to proteus H221.00 pneumonia due to pseudomonas H201.00 pneumonia due to respiratory syncytial virus H23Z.00 pneumonia due to specified organism nos H224.00
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