life Article Protective Effects of Probiotics on Cognitive and Motor Functions, Anxiety Level, Visceral Sensitivity, Oxidative Stress and Microbiota in Mice with Antibiotic-Induced Dysbiosis Alisa Arslanova 1, Aksiniya Tarasova 1, Anastasia Alexandrova 2, Vera Novoselova 2, Ilnar Shaidullov 1 , Dilyara Khusnutdinova 3, Tatiana Grigoryeva 3, Dina Yarullina 2, Olga Yakovleva 1 and Guzel Sitdikova 1,* 1 Department of Human and Animal Physiology, Institute of Fundamental Medicine and Biology, Kazan Federal University, 420008 Kazan, Republic of Tatarstan, Russia;
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[email protected] Citation: Arslanova, A.; Tarasova, A.; Abstract: Accumulating clinical and preclinical data indicate a prominent role of gut microbiota in Alexandrova, A.; Novoselova, V.; regulation of physiological functions. The gut-brain axis imbalance due to gut dysbiosis is associated Shaidullov, I.; Khusnutdinova, D.; with a range of neurodegenerative diseases. Probiotics were suggested not only to restore intestinal Grigoryeva, T.; Yarullina, D.; dysbiosis but also modulate stress response and improve mood and anxiety symptoms. In this study, Yakovleva, O.; Sitdikova, G. we assessed the effects of probiotic lactobacilli on behavioral reactions, the level of oxidative stress Protective Effects of Probiotics on and microbiota content in mice administered to broad-spectrum antibiotics.