01. – 02. D e c e m be r 2010 · Har enbe r g C i t y - c E N t e r · D o r t m u nd · g E r m a n y

01. – 02. December 2010 Harenberg City-Center · ·

TRAVEL INFORMATION venue By plane Harenberg City-Center (HCC) : Airport’s shuttle bus to the train station Holz- Königswall 21 wickede (every 15 min., time of travel 5 min.) or regional train 44137 Dortmund to the main train station of Dortmund (Dortmund Hauptbahnhof, Phone: +49 (0)231 9056-166 every 30 min., time of travel 18 min.) www.harenberg-city-center.de Düsseldorf Airport or Köln-Bonn Airport: Regional/Intercity (IC)/ (ICE) train to the main train station of Dortmund Accomodation (Dortmund Hauptbahnhof, every 30 min., time of travel 40/90 min.) In Dortmund a vast choice of accomodation at moderate and rea- By train sonable prices is available. We will provide attendees with dis­ To the main train station of Dortmund (Dortmund HBF) -> take the counted Conference rates. Please book directly at the Dortmund main exit towards the city -> turn right and walk along the Königs- Tourist office (English-speaking) by mentioning „Biotechnology wall street -> you will find the Harenberg City Center in 200 m. Conference“. A direct link can be found at the Conference web- By car site. A45 exit Do-Hafen (the harbour of Dortmund), towards the city New Biotrends Contact: center (Richtung Do-Innenstadt) -> turn right at the second set Dortmundtourismus / Dortmund Tourist Office of traffic lights –> under the train underpass -> 80 m after the Phone: +49 (0)231 18999-111 railway underpass turn to the parking site next to the Harenberg Fax: +49 (0)231 18999-333 in green chemistry City Center. Email: [email protected] www.dortmund-tourismus.de registration Exploring the potential Online Registration has started in June 2010. Local Organisation Committee Registration fees Early Registration prior Regular Registration after Oliver Kayser Frank Eiden of synthetic biology 30th September 2010 30th September 2010 Andreas Schmid Bruno Bühler Scientists e 150.00 e 200.00 for natural product discovery Students1) e 75.00 e 100.00 International Scientific Commitee Accompanying persons e 90.00 e 120.00 Oliver Kayser Marc Stadler and production 1) the reduced fee is valid for students and graduate students studying for a doc- Andreas Schmid Sarah O´Connor torate. Please submit a copy of the student-ID card on-site. Heribert Warzecha Heiko Rischer The Registration fee for the participants includes: Documenta- Ludger Wessjohann tion including the Abstract book, Coffee breaks, Lunch buffet, Finger food buffet, Lunch box. Dr. Frank Eiden BioChemGate & ChemBioTec All contributions will be published as peer reviewed proceed- Emil-Figge-Straße 66 ings in the journal “Journal of Medicinal & Spice Plants”. 44227 Dortmund Phone: +49 (0)231 755-7391 Cancellation Fax: +49 (0)231 755-7508 Cancellations must be made by writing to BioChemGate. If can- Email: [email protected] st cellation is made before 1 November 2010, all fees will be returned www.chembiotec.de but an administrative charge of 15% will be retained. There is no refund for cancellation requests made after 1st November 2010. www.biotrends.net N ew B i o t r end s i n g r een c he mistry · 01. – 02. D e c e m be r 2010 · Har enbe r g C i t y - c E N t e r · D o r t m u nd · g E r m a n y

G r ee t i n g s Wednesday, 01 December 2010 thursday, 02 December 2010

Lord Mayor City of Dortmund – Ullrich Sierau 08:00 Registration 08:30 The cell as factory Chairman: Oliver Kayser, TU Dortmund Biomedicine and biotechnology are certainly going to 10:00 Welcome be growth sectors for the next few decades. Dort- Opening by Oliver Kayser Keynote Speech mund recognized this at an early stage and paved the Welcome by the Mayor of the city of Dortmund Heiko Rischer, VTT Technical Research Centre way for developments at this location: Biotechnology Welcome by the Minister of Innovation of NRW 10:00 coffee Break is on course for growth. It has only taken a few years for Welcome by the Deutsche Bundesstiftung Umwelt (DBU) a cluster to become well-established in Dortmund which Welcome by Rector of the TU Dortmund 10:30 In vitro-cultivation of medicinal plants – sustainability already enjoys recognition in Germany and beyond. Welcome by the Dean of the faculty Bio- and Chemical and quality control Engineering Christoph Wawrosch, University of Vienna, Austria The “New BioTrends 2010 in Green Chemistry” with many renow- ned national and international scientists is an ideal platform for 11:00 Keynote Speech 11:00 Ecoefficiency and metabolic evaluation of recombinant the scientific as well as the business community to explore the Chairman: Andreas Schmid, TU Dortmund microbial biocatalysts for specific carbon oxyfunctio­ new perspectives and potentials in synthetic biology for natural Understanding and Engineering Alkaloid Biosynthesis nalization Bruno Bühler, TU Dortmund products. Sarah O´Connor, MIT, USA 12:00 Lunch buffet and poster discussion 11:30 Biocompetence@Evonik – From APIs to fine chemicals Jan Pfeffer, Evonik, Germany The organizer – Oliver Kayser 13:00 The Potential of Natural Products in Pharma Biotechnology Natural Products are in use for the treatment of di- VTT, Helsinki, Finland 12:00 Closing of the Conference and delivery of lunch boxes seases, as cosmetics or simply as food compounds. Chairman: Heiko Rischer, VTT Technical Research Centre Today, more than 50% of the clinically used drugs are Keynote Speech derived from plants or microorganisms. Recent at- Plant biotechnology and metabolic engineering for novel tempts to solve these problems by plant cell cultures pharmaceuticals – past accomplishments and a vision or isolation from plant sources could not overcome for the future the bottleneck of sufficient supply. With todays ge- Heribert Warzecha, TU Darmstadt netic and biotechnological methods we are aware to have new 14:00 Fungi as biological source for drug discovery opportunities shaping a new approach to biosynthesize desired Marc Stadler, Intermed Discovery, Germany products. We read about Synthetic Biology, Metabolic Engineering 14:30 The application of metabolomics for the study of the bio- and Combinatorial Biosynthesis, but to implement these techni- synthesis of bioactive compounds in plants and fungi ques for directed modification of medical secondary constituents, Albert Koulman, MRC HNR, United Kingdom our knowledge about producing host is still rather poor. To our surprise challenging questions have not been addressed to me- 15:00 coffee Break Foyer dicinally used natural products. The development of natural pro- 16:00 Metabolic Engineering and pathway design ducts and related production processes all the way from the idea TU Darmstadt over R & D to marketing is a complex and time-consuming task Chairman: Hansjörg Hagels, Boehringer Ingelheim and requires continuous economic and quality-assuring decision- Mechanistic and Appliciation Aspects of Alkylating making along the value added chain. Even more eco-efficiency Enzymes thereby comes also into consideration, serving as a basis for the Ludger Wessjohann, IPB Halle, Germany decision-making process. 16:30 Microorganisms as factory for synthesis of bioactive The meeting in Dortmund is an excellent opportunity in time and flavonoids place to meet the experts in this field and to work out a regional Stefan Martens, FEM-IASMA, San Michele all´Adige, Italy or even global vision. In an extraordinarily stimulating environment 17:00 Metabolic engineering of terpenoids for green surrounded by leading industrial partners situated at the Techni- pharmaceuticals cal University Dortmund, world leading academic and institutional Harro Bouwmeester, U Wageningen, Netherlands partners come together to work out visions and engineering stra- 17:30 Title to be announced tegies to provide solutions for exploring nature’s Bounty to explore To be selected from attendees the hidden green gold. 18:00 Welcome Reception with buffet