Religion, Morality, and Childhood Vaccination Law Ross D
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The Implementation of Mass-Vaccination Against SARS-Cov-2: a Systematic Review of Existing Strategies and Guidelines
Review The Implementation of Mass-Vaccination against SARS-CoV-2: A Systematic Review of Existing Strategies and Guidelines Tasnim Hasan 1,2, Justin Beardsley 1, Ben J. Marais 3 , Thu Anh Nguyen 2 and Greg J. Fox 1,2,* 1 Faculty of Medicine and Health, The University of Sydney, Sydney, NSW 2006, Australia; [email protected] (T.H.); [email protected] (J.B.) 2 The Woolcock Institute of Medical Research, Glebe, NSW 2037, Australia; [email protected] 3 Marie Bahir Institute, The University of Sydney, Westmead, NSW 2145, Australia; [email protected] * Correspondence: [email protected] Abstract: The global drive to vaccinate against severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) began in December 2020 with countries in Europe, Middle East, and North America leading the roll out of a mass-vaccination program. This systematic review synthesised all available English-language guidelines and research regarding mass-vaccination for COVID-19 until 1 March 2021—the first three months of the global mass-vaccination effort. Data were extracted from national websites, PubMed, Embase, Medline and medRxiv, including peer and non-peer review research findings. A total of 15 national policy documents were included. Policies were summarised according to the World Health Organisation (WHO) framework for mass vaccination. All included policies prioritised front-line health care workers and the elderly. Limited information was available regarding staffing, cold chain, communication strategies and infrastructure requirements for effective vaccine Citation: Hasan, T.; Beardsley, J.; delivery. A total of 26 research studies were identified, reporting roll-out strategies, vaccine uptake Marais, B.J.; Nguyen, T.A.; Fox, G.J. -
From the Factory to the Frontlines the Operation Warp Speed Strategy for Distributing a COVID-19 Vaccine
From the Factory to the Frontlines The Operation Warp Speed Strategy for Distributing a COVID-19 Vaccine What This Strategy Aims to Do This report to Congress details a strategy to achieve the principal purpose and objective of Operation Warp Speed (OWS): ensuring that every American who wants to receive a COVID-19 vaccine can receive one, by delivering safe and effective vaccine doses to the American people beginning January 2021. The leadership of OWS has committed to being transparent with Congress, the media, and the American people. OWS has provided regular briefings on topics of interest to Congress and the media and will continue to provide updates and announcements as OWS reaches new milestones. Congress has been a vital partner in the all-of-America response to the COVID-19 pandemic. With support provided through emergency supplemental and flexible discretionary funding, OWS has now made strong progress toward a safe and effective COVID-19 vaccine, with multiple candidates in Phase 3 clinical trials. Simultaneously, OWS and partners are developing a plan for delivering a safe and effective product to Americans as quickly and reliably as possible. Experts from the Department of Health and Human Services (HHS) are leading vaccine development, while experts from the Department of Defense (DoD) are partnering with the Centers for Disease Control and Prevention (CDC) and other parts of HHS to coordinate supply, production, and distribution of vaccines. Successful implementation of the national COVID-19 vaccination program requires precise coordination across federal, state, local, tribal, and territorial governments and among many public and private partners. -
Program Evaluation Key Outcomes and Addressing Remaining
Vaccine 31S (2013) J73–J78 Contents lists available at ScienceDirect Vaccine jou rnal homepage: www.elsevier.com/locate/vaccine Key outcomes and addressing remaining challenges—Perspectives from a final ଝ evaluation of the China GAVI project a,1 a,1 a,1 a,1 b c Weizhong Yang , Xiaofeng Liang , Fuqiang Cui , Li Li , Stephen C. Hadler , Yvan J. Hutin , d a,∗ Mark Kane , Yu Wang a Chinese Center for Disease Control and Prevention, Beijing, China b Centers for Disease Control and Prevention, Atlanta, USA c Europe Center for Disease Control and Prevention, Stockholm, Sweden d Mercer Island, Washington, USA a r t a b i c s t l r e i n f o a c t Article history: During the China GAVI project, implemented between 2002 and 2010, more than 25 million children Received 6 June 2012 received hepatitis B vaccine with the support of project, and the vaccine proved to be safe and effective. Received in revised form 24 July 2012 With careful consideration for project savings, China and GAVI continually adjusted the budget, addi- Accepted 24 September 2012 tionally allowing the project to spend operational funds to support demonstration projects to improve timely birth dose (TBD), conduct training of EPI staff, and to monitor the project impact. Results from the final evaluation indicated the achievement of key outcomes. As a result of government co-investment, Keywords: human resources at county level engaged in hepatitis B vaccination increased from 29 per county on GAVI Project average in 2002 to 66 in 2009. All project counties funded by the GAVI project use auto-disable syringes Outcomes for hepatitis B vaccination and other vaccines. -
Provided By: Techserve Alliance
Provided by: TechServe Alliance Table of Contents Introduction .............................................................................................. 4 Return-to-Work at a Glance ....................................................................... 5 COVID-19 Return-to-Work Plans ..................................................................................... 5 Other Return-to-Work Considerations ........................................................................... 7 COVID-19 Vaccine Overview ....................................................................... 8 COVID-19 Vaccines and the Workplace ..................................................... 11 Government Guidance Related to COVID-19 Vaccines and Workplaces ...................11 OSHA Perspective ............................................................................... 11 EEOC Perspective ................................................................................ 11 Deciding Between a Mandatory or Voluntary Vaccination Policy ..............................13 General Employer Considerations ..................................................... 13 The Case for Mandatory Workplace Vaccination............................. 14 The Case for Voluntary Workplace Vaccination ............................... 14 Developing a Workplace Vaccination Plan ...................................................................16 Step 1: Gauge the Situation .............................................................. 16 Step 2: Make the Choice ................................................................... -
Would Parents Get Their Children Vaccinated Against SARS-Cov-2? Rate and Predictors of Vaccine Hesitancy According to a Survey Over 5000 Families from Bologna, Italy
Article Would Parents Get Their Children Vaccinated Against SARS-CoV-2? Rate and Predictors of Vaccine Hesitancy According to a Survey over 5000 Families from Bologna, Italy Marco Montalti 1,* , Flavia Rallo 1, Federica Guaraldi 2, Lapo Bartoli 3, Giulia Po 4 , Michela Stillo 5, Paola Perrone 5, Lorena Squillace 5, Laura Dallolio 1 , Paolo Pandolfi 5, Davide Resi 5, Maria Pia Fantini 1 , Chiara Reno 1 and Davide Gori 1 1 Unit of Hygiene, Department of Biomedical and Neuromotor Sciences, Public Health and Medical Statistics, University of Bologna, 40126 Bologna, Italy; fl[email protected] (F.R.); [email protected] (L.D.); [email protected] (M.P.F.); [email protected] (C.R.); [email protected] (D.G.) 2 IRCCS Istituto delle Scienze Neurologiche di Bologna, 40139 Bologna, Italy; [email protected] 3 Unit of Primary Health Care, Department of Medical and Surgical Sciences, University of Bologna, 40126 Bologna, Italy; [email protected] 4 School of Hygiene and Preventive Medicine, University of Ferrara, 44121 Ferrara, Italy; [email protected] 5 Department of Public Health, Bologna Local Health Authority, 40124 Bologna, Italy; [email protected] (M.S.); [email protected] (P.P.); [email protected] (L.S.); paolo.pandolfi@ausl.bologna.it (P.P.); [email protected] (D.R.) * Correspondence: [email protected]; Tel.: +39-051-209-4802 Citation: Montalti, M.; Rallo, F.; Guaraldi, F.; Bartoli, L.; Po, G.; Stillo, Abstract: In the near future, COVID-19 vaccine efficacy trials in larger cohorts may offer the possibility M.; Perrone, P.; Squillace, L.; Dallolio, to implement child and adolescent vaccination. -
UNHCR COVID-19 Global Emergency Response
GLOBAL COVID-19 EMERGENCY RESPONSE 17 February 2021 UNHCR COVID-19 Preparedness and Response Highlights COVID-19 update ■ UNHCR and Gavi, the Vaccine Alliance, signed a Memorandum of Over 46,000 Understanding (MoU) on 03 February 2020, with the overall goal of ensuring reported cases refugees and other forcibly displaced can access vaccines on par with of COVID-19 nationals. The MoU also looks at expanding coverage and quality of among forcibly displaced people immunization services, promoting equity in access and uptake of vaccines, and strengthening health systems at community and primary care level. across 103 countries ■ Jordan has become one of the world’s first countries to start COVID-19 vaccinations for refugees, including vaccinations in Za’atari refugee camp on 15 February. UNHCR has been working with the Jordanian government to increase of vaccinate refugees and provide critical health, sanitation, hygiene and logistical some 7,500 cases compared support. UNHCR appeals to all countries to follow suit and include refugees in to the previous their national vaccination drives in line with COVAX allocation principles. reporting period ■ In 2020, 39.4 million persons of concern received COVID-19 assistance (numbers as of 08 February including access to protection services, shelter, health, and education. This 2021) includes over 8.5 million individuals who received cash assistance. ■ Despite an estimated 1.44 million refugees in urgent need of resettlement globally, less than 23,000 were resettled through UNHCR last year. These are the lowest refugee resettlement numbers UNHCR has witnessed in almost two decades. The drop stems from low quotas put forward by states, as well as the impact of COVID-19, which delayed departures and programmes. -
Vaccine Hesitancy
WHY CHILDREN WORKSHOP ON IMMUNIZATIONS ARE NOT VACCINATED? VACCINE HESITANCY José Esparza MD, PhD - Adjunct Professor, Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD, USA - Robert Koch Fellow, Robert Koch Institute, Berlin, Germany - Senior Advisor, Global Virus Network, Baltimore, MD, USA. Formerly: - Bill & Melinda Gates Foundation, Seattle, WA, USA - World Health Organization, Geneva, Switzerland The value of vaccination “The impact of vaccination on the health of the world’s people is hard to exaggerate. With the exception of safe water, no other modality has had such a major effect on mortality reduction and population growth” Stanley Plotkin (2013) VACCINES VAILABLE TO PROTECT AGAINST MORE DISEASES (US) BASIC VACCINES RECOMMENDED BY WHO For all: BCG, hepatitis B, polio, DTP, Hib, Pneumococcal (conjugated), rotavirus, measles, rubella, HPV. For certain regions: Japanese encephalitis, yellow fever, tick-borne encephalitis. For some high-risk populations: typhoid, cholera, meningococcal, hepatitis A, rabies. For certain immunization programs: mumps, influenza Vaccines save millions of lives annually, worldwide WHAT THE WORLD HAS ACHIEVED: 40 YEARS OF INCREASING REACH OF BASIC VACCINES “Bill Gates Chart” 17 M GAVI 5.6 M 4.2 M Today (ca 2015): <5% of children in GAVI countries fully immunised with the 11 WHO- recommended vaccines Seth Berkley (GAVI) The goal: 50% of children in GAVI countries fully immunised by 2020 Seth Berkley (GAVI) The current world immunization efforts are achieving: • Equity between high and low-income countries • Bringing the power of vaccines to even the world’s poorest countries • Reducing morbidity and mortality in developing countries • Eliminating and eradicating disease WHY CHILDREN ARE NOT VACCINATED? •Vaccines are not available •Deficient health care systems •Poverty •Vaccine hesitancy (reticencia a la vacunacion) VACCINE HESITANCE: WHO DEFINITION “Vaccine hesitancy refers to delay in acceptance or refusal of vaccines despite availability of vaccination services. -
Predictors of Vaccine Hesitancy: Implications for COVID-19 Public Health Messaging
International Journal of Environmental Research and Public Health Review Predictors of Vaccine Hesitancy: Implications for COVID-19 Public Health Messaging Amanda Hudson 1,2,* and William J. Montelpare 3 1 Department of Mental Health and Addiction, Health PEI, Charlottetown, PE C1C 1M3, Canada 2 Department of Health Management, University of Prince Edward Island, Charlottetown, PE C1A 4P3, Canada 3 Department of Applied Human Sciences, University of Prince Edward Island, Charlottetown, PE C1A 4P3, Canada; [email protected] * Correspondence: [email protected] Abstract: Objectives: Successful immunization programs require strategic communication to increase confidence among individuals who are vaccine-hesitant. This paper reviews research on determinants of vaccine hesitancy with the objective of informing public health responses to COVID-19. Method: A literature review was conducted using a broad search strategy. Articles were included if they were published in English and relevant to the topic of demographic and individual factors associated with vaccine hesitancy. Results and Discussion: Demographic determinants of vaccine hesitancy that emerged in the literature review were age, income, educational attainment, health literacy, rurality, and parental status. Individual difference factors included mistrust in authority, disgust sensitivity, and risk aversion. Conclusion: Meeting target immunization rates will require robust public health campaigns that speak to individuals who are vaccine-hesitant in their attitudes and behaviours. Based on the assortment of demographic and individual difference factors that contribute Citation: Hudson, A.; Montelpare, to vaccine hesitancy, public health communications must pursue a range of strategies to increase W.J. Predictors of Vaccine Hesitancy: public confidence in available COVID-19 vaccines. Implications for COVID-19 Public Health Messaging. -
Building Global Momentum for Adult Vaccination Policy Within COVID-19 Series: Making COVID-19 a Springboard for Adult Vaccinations
Building Global Momentum for Adult Vaccination Policy within COVID-19 Series: Making COVID-19 a Springboard for Adult Vaccinations Executive Summary Dr. Michael Moore Dr. Monika Arora Past-President Chair World Federation of Public Health NCD Alliance India Associations (WFPHA) 08 June 2021 This project is supported by an unrestricted educational grant from Pfizer Global. Context Successful national immunization programmes depend on up-to-date policies and effective strategies in order to achieve and sustain their goals. While many national programmes are built on a life course approach from birth to end-of-life, at-risk populations frequently defined by older age and those with co-morbidities have until very recently received much less attention than the pediatric program. This is most starkly noted with the WHO influenza targets of 90% for children and 75% for older people¹. The reasons for the disparity could be grounded in a lack of data, or even the scientific debate on the effectiveness of vaccines in older age, the optics of inequality are evident. The COVID-19 pandemic has without question exposed the brutal consequences of infectious diseases for the most at-risk populations which includes healthy older people as well as those with chronic conditions². The pandemic has also unearthed an uncomfortable structural and societal ageism affecting the human rights of millions of people around the world. From hospital triaging guidelines to chronic understaffing of long-term care facilities, national health systems did not take the necessary steps to ensure that vulnerable people had access to life-saving health services, regardless of age or socioeconomic background³. -
COVID-19 Vaccines: Summary of Current State-Of-Play Prepared Under Urgency 21 May 2020 – Updated 16 July 2020
Office of the Prime Minister’s Chief Science Advisor Kaitohutohu Mātanga Pūtaiao Matua ki te Pirimia COVID-19 vaccines: Summary of current state-of-play Prepared under urgency 21 May 2020 – updated 16 July 2020 The COVID-19 pandemic has spurred a global effort to find a vaccine to protect people from SARS- CoV-2 infection. This summary highlights selected candidates, explains the different types of vaccines being investigated and outlines some of the potential issues and risks that may arise during the clinical testing process and beyond. Key points • There are at least 22 vaccine candidates registered in clinical (human) trials, out of a total of at least 194 in various stages of active development. • It is too early to choose a particular frontrunner as we lack safety and efficacy information for these candidates. • It is difficult to predict when a vaccine will be widely available. The fastest turnaround from exploratory research to vaccine approval was previously 4–5 years (ebolavirus vaccine), although it is likely that current efforts will break this record. • There are a number of challenges associated with accelerated vaccine development, including ensuring safety, proving efficacy in a rapidly changing pandemic landscape, and scaling up manufacture. • The vaccine that is licensed first will not necessarily confer full or long-lasting protection. 1 Contents Key points .................................................................................................................................. 1 1. Types of vaccines ............................................................................................................... -
Vaccine Adjuvants: from 1920 to 2015 and Beyond
Vaccines 2015, 3, 320-343; doi:10.3390/vaccines3020320 OPEN ACCESS vaccines ISSN 2076-393X www.mdpi.com/journal/vaccines Review Vaccine Adjuvants: from 1920 to 2015 and Beyond Alberta Di Pasquale 1,*, Scott Preiss 1, Fernanda Tavares Da Silva 1 and Nathalie Garçon 2 1 GSK Vaccines, Avenue Fleming, 1300 Wavre, Belgium; E-Mails: [email protected] (S.P.); [email protected] (F.T.D.S.) 2 Bioaster, 321 Avenue Jean Jaurès, 6700 Lyon, France; E-Mail: [email protected] * Author to whom correspondence should be addressed; E-Mail: [email protected]; Tel.: +32-10-85-3573. Academic Editor: Diane M. Harper Received: 23 February 2015 / Accepted: 9 April 2015 / Published: 16 April 2015 Abstract: The concept of stimulating the body’s immune response is the basis underlying vaccination. Vaccines act by initiating the innate immune response and activating antigen presenting cells (APCs), thereby inducing a protective adaptive immune response to a pathogen antigen. Adjuvants are substances added to vaccines to enhance the immunogenicity of highly purified antigens that have insufficient immunostimulatory capabilities, and have been used in human vaccines for more than 90 years. While early adjuvants (aluminum, oil-in-water emulsions) were used empirically, rapidly increasing knowledge on how the immune system interacts with pathogens means that there is increased understanding of the role of adjuvants and how the formulation of modern vaccines can be better tailored towards the desired clinical benefit. Continuing safety evaluation of licensed vaccines containing adjuvants/adjuvant systems suggests that their individual benefit-risk profile remains favorable. -
National Deployment & Vaccination Plan
NATIONAL DEPLOYMENT & VACCINATION EPI PLAN (NDVP)FOR COVID-19 VACCINES 24th June 2021 (2021) Expanded Program on Immunization | Ministry of National Health Services Regulations & Coordination Islamabad 1 Table of Contents Introduction Country Profile Planning and Coordination Regulatory Preparedness Identification of Target Population Costing and Funding Vaccine Delivery Strategy Supply Chain Management Microplanning Human Resource Management and Training Recording and Reporting Healthcare Waste Management RCCE, Vaccine Acceptance and Uptake Monitoring Surveillance and AEFI Evaluation 2 List of Acronyms Acronym Full name ADB Asian Development Bank AEFI Adverse Event Following Immunization AJK Azad Jammu and Kashmir BAL Balochistan BHU Basic Health Unit CBV Community Based Volunteer CDA Capital Development Authority CEPI Coalition for Epidemic Preparedness Innovations CHWs Community Health Workers CMW Community Midwife COVID Coronavirus Disease CSOs Civil Society Organizations CVC COVID-19 Vaccination Counter CVT COVID-19 Vaccination Team CVIC COVID-19 Vaccine Introduction Costing Tool DHO District Health Officer DHQ District Headquarter DQA Data Quality Assessment DRAP Drug Regulatory Authority of Pakistan EMRO Eastern Mediterranean Regional Office EOC Emergency Operation Center EPI Expanded Program on Immunization FATA Federally Administered Tribal Areas FIC Fully Immunized Child GAVI The Vaccine Alliance GACVS Global Advisory Committee on Vaccine Safety GB Gilgit-Baltistan GF Gates Foundation HCP Health Care Provider ICC Inter-Agency